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David Lewis Perez, M.D.

Title
Institution
Department
Address

Biography
Columbia UniversityBA05/2003Neuroscience & Behavior
New York University School of MedicineMD05/2007Medicine
MGH/BWH Partners Neurology Residency06/2011Neurology
BIDMC/BWH Harvard Longwood Psychiatry Residency06/2014Psychiatry - Research Concentration
Harvard Medical SchoolMMSc05/2016Clinical & Translational Investigation
2003
Cum Laude, Columbia University
2007
Alpha Omega Alpha, New York University School of Medicine
2012
Outstanding Psychiatry Resident Teacher, Harvard Medical School
2012
Young Investigator Award, American Neuropsychiatric Association (ANPA)
2013
Joseph J. Schildraut Psychiatry Research Award
2013
Partners in Excellence Team Award - Spanish Neurology Program
2014
Career Development Award, American Neuropsychiatric Association (ANPA)
2016
MGH ECOR Clinician-Scientist Career Development Award
2018
Diplomate - UCNS Behavioral Neurology-Neuropsychiatry
2021
Fellow - American Academy of Neurology (FAAN)
2022
Fellow - American Neuropsychiatric Association (FANPA)

Overview
David L. Perez MD, MMSc, a dual-trained neurologist-psychiatrist, is a faculty member in the Departments of Neurology and Psychiatry at the Massachusetts General Hospital. Dr. Perez is the Founding Director of the multidisciplinary Functional Neurological Disorder (FND) Unit. The FND Unit includes neurologists, psychiatrists, psychotherapists, physiotherapists, occupational therapists, speech and language pathologists, neuropsychologists, and research scientists. In the MGH outpatient FND Clinical Program, specialized, integrated neurologic and psychiatric consultations are provided for patients experiencing FND, including individuals with functional/dissociative seizures, functional movement disorder, functional limb weakness, functional cognitive disorder and persistent postural perceptual dizziness.

Dr. Perez is also the Director of the MGH Functional Neurological Disorder Research Program, which is dedicated to the comprehensive clinical and neurobiological investigation of FND. Currently, the laboratory uses neuropsychiatric research assessments and advanced structural and functional magnetic resonance imaging (MRI) techniques to investigate clinical and neurobiological markers of symptom severity, disease-risk, subtype and clinical outcomes across individuals with functional seizures, functional movement disorder and functional limb weakness.

Dr. Perez is affiliated with the MGH/HST Athinoula A. Martinos Center for Biomedical Imaging, and collaborates with other investigators within the Harvard Medical School Hospital system. Dr. Perez is a member of the Cognitive Behavioral Neurology and Neuropsychiatry Divisions at the Massachusetts General Hospital.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01MH125802 (PEREZ, DAVID LEWIS) Apr 1, 2021 - Mar 31, 2026
    NIH
    Defining Neurobiological Subtypes of Motor Functional Neurological Disorder
    Role: Principal Investigator
  2. K23MH111983 (PEREZ, DAVID LEWIS) Sep 14, 2017 - Aug 31, 2022
    NIH
    Neuroimaging Biomarkers of Symptom Severity, Adverse Life Events and Prognosis in Motor Functional Neurological Disorders
    Role: Principal Investigator
  3. R25NS065743 (PEREZ, DAVID LEWIS) Jul 1, 2013 - Jun 30, 2015
    NIH
    Functional and Structural Biomarkers of Psychogenic Nonepileptic Seizures
    Role: Principal Investigator

Featured Content

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Jungilligens J, Popkirov S, Perez DL, Diez I. Linking gene expression patterns and brain morphometry to trauma and symptom severity in patients with functional seizures. Psychiatry Res Neuroimaging. 2022 Aug 27; 326:111533. PMID: 36055038.
    Citations:    
  2. Jungilligens J, Paredes-Echeverri S, Popkirov S, Barrett LF, Perez DL. A new science of emotion: implications for functional neurological disorder. Brain. 2022 08 27; 145(8):2648-2663. PMID: 35653495.
    Citations:    Fields:    
  3. Picon EL, Todorova EV, Palombo DJ, Perez DL, Howard AK, Silverberg ND. Memory Perfectionism is Associated with Persistent Memory Complaints after Concussion. Arch Clin Neuropsychol. 2022 Aug 23; 37(6):1177-1184. PMID: 35443277; PMCID: PMC9396453.
    Citations:    Fields:    
  4. Maggio J, Kyle K, Stephen CD, Perez DL. Lessons Learned in Outpatient Physical Therapy for Motor Functional Neurological Disorder. J Neurol Phys Ther. 2022 Aug 16. PMID: 35980727.
    Citations:    
  5. Saxena A, Perez DL. Neuropsychiatry for the Neurologist. Semin Neurol. 2022 04; 42(2):78-79. PMID: 35675819.
    Citations:    Fields:    Translation:Humans
  6. Sojka P, Slovák M, Vechetová G, Jech R, Perez DL, Serranová T. Bridging structural and functional biomarkers in functional movement disorder using network mapping. Brain Behav. 2022 05; 12(5):e2576. PMID: 35429407; PMCID: PMC9120728.
    Citations: 1     Fields:    Translation:Humans
  7. LaFaver K, Maurer CW, Nicholson TR, Perez DL. Current Clinical Neurology. Functional Movement Disorder: An Interdisciplinary Case-Based Approach. 2022; 463. View Publication.
  8. Anderson JR, Perez DL, Price BH. Functional Movement Disorder: An Interdisciplinary Case-Based Approach. Integrating Neurologic and Psychiatric Perspectives in Functional Movement Disorder. 2022; 39-49. View Publication.
  9. Adams C, Perez DL. Functional Movement Disorder: An Interdisciplinary Case-Based Approach. Beyond Functional Movements: The Spectrum of Functional Neurological and Somatic Symptoms. 2022; 169-181. View Publication.
  10. LaFaver K, Maurer CW, Nicholson TR, Perez DL. Functional Movement Disorder: An Interdisciplinary Case-Based Approach. Choosing a Career in Functional Movement Disorder. 2022; 451-457. View Publication.
  11. Finkelstein SA, Adams C, Tuttle M, Saxena A, Perez DL. Neuropsychiatric Treatment Approaches for Functional Neurological Disorder: A How to Guide. Semin Neurol. 2022 04; 42(2):204-224. PMID: 35189644.
    Citations:    Fields:    Translation:Humans
  12. Zelinski L, Diez I, Perez DL, Kotz SA, Wellmer J, Schlegel U, Popkirov S, Jungilligens J. Cortical thickness in default mode network hubs correlates with clinical features of dissociative seizures. Epilepsy Behav. 2022 03; 128:108605. PMID: 35152170.
    Citations:    Fields:    Translation:Humans
  13. Oriuwa C, Mollica A, Feinstein A, Giacobbe P, Lipsman N, Perez DL, Burke MJ. Neuromodulation for the treatment of functional neurological disorder and somatic symptom disorder: a systematic review. J Neurol Neurosurg Psychiatry. 2022 03; 93(3):280-290. PMID: 35115389.
    Citations: 1     Fields:    Translation:Humans
  14. Saxena A, Paredes-Echeverri S, Michaelis R, Popkirov S, Perez DL. Using the Biopsychosocial Model to Guide Patient-Centered Neurological Treatments. Semin Neurol. 2022 04; 42(2):80-87. PMID: 35114695.
    Citations: 1     Fields:    Translation:Humans
  15. Aybek S, Perez DL. Diagnosis and management of functional neurological disorder. BMJ. 2022 01 24; 376:o64. PMID: 35074803.
    Citations: 2     Fields:    Translation:Humans
  16. MacLean J, Finkelstein SA, Paredes-Echeverri S, Perez DL, Ranford J. Sensory Processing Difficulties in Patients with Functional Neurological Disorder: Occupational Therapy Management Strategies and Two Cases. Semin Pediatr Neurol. 2022 04; 41:100951. PMID: 35450672.
    Citations:    Fields:    Translation:Humans
  17. Thurin K, Patel V, Perez DL, Dickerson BC, Hochberg D, Quimby M, Miller MB, Feany M, Silbersweig D, McGinnis SM, Daffner KR, Gale SA. Case Study 2: A 60-Year-Old Man With Progressive Deficits in Language Output. J Neuropsychiatry Clin Neurosci. 2022; 34(3):196-203. PMID: 35921620.
    Citations:    
  18. Hebb C, Raynor G, Perez DL, Nappi-Kaehler J, Polich G. The use of rhythmic auditory stimulation for functional gait disorder: A case report. NeuroRehabilitation. 2022; 50(2):219-229. PMID: 35213331.
    Citations:    Fields:    Translation:Humans
  19. Polich G, Zalanowski S, Maney J, Perez DL, Baslet G, Maggio J, O'Neal MA, Dworetzky B, Herman S. Development of an inpatient rehabilitation pathway for motor functional neurological disorders: Initial reflections. NeuroRehabilitation. 2022; 50(2):231-243. PMID: 35213332.
    Citations:    Fields:    Translation:Humans
  20. Molton IR, Keatley E, Jaywant A, Josephy-Hernandez S, Rivas-Grajales AM, Perez DL, Mukherjee D. Ethical issues in the treatment of functional neurological disorder. PM R. 2022 01; 14(1):112-119. PMID: 34958180.
    Citations:    Fields:    Translation:Humans
  21. Sojka P, Paredes-Echeverri S, Perez DL. Are Functional (Psychogenic Nonepileptic) Seizures the Sole Expression of Psychological Processes? Curr Top Behav Neurosci. 2022; 55:329-351. PMID: 33768494.
    Citations: 1     Fields:    Translation:Humans
  22. Godena EJ, Perez DL, Crain LD, Fishel AK, Flaherty A, Harley R, Cohen JN. Psychotherapy for Functional Neurological (Conversion) Disorder: A Case Bridging Mind, Brain, and Body. J Clin Psychiatry. 2021 11 02; 82(6). PMID: 34727420.
    Citations:    Fields:    Translation:Humans
  23. Perez DL. Expanding Access to Specialty Care Using Video-Telehealth: The Case for Functional Neurological Disorder. J Acad Consult Liaison Psychiatry. 2021 Nov-Dec; 62(6):667-668. PMID: 34806594.
    Citations: 1     Fields:    Translation:Humans
  24. Picon EL, Perez DL, Burke MJ, Debert CT, Iverson GL, Panenka WJ, Silverberg ND. Unexpected symptoms after concussion: Potential links to functional neurological and somatic symptom disorders. J Psychosom Res. 2021 12; 151:110661. PMID: 34739941.
    Citations: 1     Fields:    Translation:Humans
  25. Paredes-Echeverri S, Maggio J, Bègue I, Pick S, Nicholson TR, Perez DL. Autonomic, Endocrine, and Inflammation Profiles in Functional Neurological Disorder: A Systematic Review and Meta-Analysis. J Neuropsychiatry Clin Neurosci. 2022; 34(1):30-43. PMID: 34711069; PMCID: PMC8813876.
    Citations:    Fields:    Translation:Humans
  26. Wardrope A, Dworetzky BA, Barkley GL, Baslet G, Buchhalter J, Doss J, Goldstein LH, Hallett M, Kozlowska K, LaFrance WC, McGonigal A, Mildon B, Oto M, Perez DL, Riker E, Roberts NA, Stone J, Tolchin B, Reuber M. How to do things with words: Two seminars on the naming of functional (psychogenic, non-epileptic, dissociative, conversion, …) seizures. Seizure. 2021 Dec; 93:102-110. PMID: 34740139; PMCID: PMC9308960.
    Citations:    Fields:    Translation:Humans
  27. Tolchin B, Baslet G, Carson A, Dworetzky BA, Goldstein LH, LaFrance WC, Martino S, Perez DL, Reuber M, Stone J, Szaflarski JP. The role of evidence-based guidelines in the diagnosis and treatment of functional neurological disorder. Epilepsy Behav Rep. 2021; 16:100494. PMID: 34877515; PMCID: PMC8627961.
    Citations: 2     
  28. Perez DL. Expanding the therapeutic toolkit in functional neurological disorder: consensus recommendations for speech and language therapy. J Neurol Neurosurg Psychiatry. 2021 10; 92(10):1026. PMID: 34210803.
    Citations: 2     Fields:    Translation:Humans
  29. Kim DD, Kung CS, Perez DL. Helping the Public Understand Adverse Events Associated With COVID-19 Vaccinations: Lessons Learned From Functional Neurological Disorder. JAMA Neurol. 2021 07 01; 78(7):789-790. PMID: 33835153.
    Citations: 14     Fields:    Translation:HumansPHPublic Health
  30. Bègue I, Nicholson TR, Kozlowska K, LaFrance WC, Levenson JL, Rapaport MH, Carson AJ, Perez DL. Psychiatry's modern role in functional neurological disorder: join the renaissance. Psychol Med. 2021 Jun 24; 1-3. PMID: 34167595.
    Citations: 1     Fields:    
  31. Madva EN, Perez DL. Ferri’s Clinical Advisor 2022. Functional Neurological (Conversion) Disorder. 2021.
  32. Stephen CD, Perez DL, Chibnik LB, Sharma N. Functional dystonia: A case-control study and risk prediction algorithm. Ann Clin Transl Neurol. 2021 04; 8(4):732-748. PMID: 33724724.
    Citations: 3     Fields:    Translation:Humans
  33. Asadi-Pooya AA, Brigo F, Kozlowska K, Perez DL, Pretorius C, Sawchuk T, Saxena A, Tolchin B, Valente KD. Social aspects of life in patients with functional seizures: Closing the gap in the biopsychosocial formulation. Epilepsy Behav. 2021 04; 117:107903. PMID: 33740497.
    Citations: 4     Fields:    Translation:Humans
  34. Perez DL, Edwards MJ, Nielsen G, Kozlowska K, Hallett M, LaFrance WC. Decade of progress in motor functional neurological disorder: continuing the momentum. J Neurol Neurosurg Psychiatry. 2021 Mar 15. PMID: 33722822; PMCID: PMC8440656.
    Citations: 9     Fields:    
  35. Perez DL, Nicholson TR, Asadi-Pooya AA, Bègue I, Butler M, Carson AJ, David AS, Deeley Q, Diez I, Edwards MJ, Espay AJ, Gelauff JM, Hallett M, Horovitz SG, Jungilligens J, Kanaan RAA, Tijssen MAJ, Kozlowska K, LaFaver K, LaFrance WC, Lidstone SC, Marapin RS, Maurer CW, Modirrousta M, Reinders AATS, Sojka P, Staab JP, Stone J, Szaflarski JP, Aybek S. Neuroimaging in Functional Neurological Disorder: State of the Field and Research Agenda. Neuroimage Clin. 2021; 30:102623. PMID: 34215138.
    Citations: 13     Fields:    Translation:Humans
  36. Eldaief MC, Perez DL, Quimby M, Hochberg D, Touroutoglou A, Feldman Barrett L, Dickerson BC. Atrophy in Distinct Corticolimbic Networks Subserving Socioaffective Behavior in Semantic Variant Primary Progressive Aphasia. Dement Geriatr Cogn Disord. 2020; 49(6):589-597. PMID: 33691310; PMCID: PMC8812818.
    Citations:    Fields:    Translation:Humans
  37. Frucht L, Perez DL, Callahan J, MacLean J, Song PC, Sharma N, Stephen CD. Functional Dystonia: Differentiation From Primary Dystonia and Multidisciplinary Treatments. Front Neurol. 2020; 11:605262. PMID: 33613415.
    Citations: 5     
  38. Perez DL, Murray ED, Forester BP, Price BH. Bradley's Neurology in Clinical Practice - 8th Edition. Chapter 10: Depression and Psychosis in Neurological Practice. 2021.
  39. Saxena A, Perez DL. A transdiagnostic and biopsychosocial-informed perspective across functional seizures and functional movement disorder. Epilepsy Behav. 2021 04; 117:107749. PMID: 33509632.
    Citations:    Fields:    Translation:Humans
  40. Price BH, Perez DL, Rapalino O, Oakley DH. Case 41-2020: A 62-Year-Old Man with Memory Loss and Odd Behavior. N Engl J Med. 2020 Dec 31; 383(27):2666-2675. PMID: 33382934.
    Citations:    Fields:    Translation:Humans
  41. Sojka P, Diez I, Bareš M, Perez DL. Individual differences in interoceptive accuracy and prediction error in motor functional neurological disorders: A DTI study. Hum Brain Mapp. 2021 04 01; 42(5):1434-1445. PMID: 33615622.
    Citations: 3     Fields:    Translation:Humans
  42. Perez DL, Hunt A, Sharma N, Flaherty A, Caplan D, Schmahmann JD. Cautionary notes on diagnosing functional neurologic disorder as a neurologist-in-training. Neurol Clin Pract. 2020 Dec; 10(6):484-487. PMID: 33520411.
    Citations: 3     
  43. Maggio J, Alluri PR, Paredes-Echeverri S, Larson AG, Sojka P, Price BH, Aybek S, Perez DL. Briquet syndrome revisited: implications for functional neurological disorder. Brain Commun. 2020; 2(2):fcaa156. PMID: 33426523.
    Citations: 5     
  44. Saxena A, Godena E, Maggio J, Perez DL. Towards an Outpatient Model of Care for Motor Functional Neurological Disorders: A Neuropsychiatric Perspective. Neuropsychiatr Dis Treat. 2020; 16:2119-2134. PMID: 32982250; PMCID: PMC7509337.
    Citations: 1     
  45. Drane DL, Fani N, Hallett M, Khalsa SS, Perez DL, Roberts NA. A framework for understanding the pathophysiology of functional neurological disorder. CNS Spectr. 2020 Sep 04; 1-7. PMID: 32883381; PMCID: PMC7930164.
    Citations: 13     Fields:    
  46. Perez DL, Biffi A, Camprodon JA, Caplan DN, Chemali Z, Kritzer MD, Moo LR, Newhouse AL, Ramirez-Gomez L, Razafsha M, Tanev KS, Schmahmann JD. Telemedicine in Behavioral Neurology-Neuropsychiatry: Opportunities and Challenges Catalyzed by COVID-19. Cogn Behav Neurol. 2020 09; 33(3):226-229. PMID: 32889955.
    Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
  47. Tolchin B, Perez DL, Szaflarski JP, Baslet G, Doss J, Buchhalter J, Sawchuk T, Dworetzky BA. What's in a name? Epilepsy Behav. 2020 11; 112:107364. PMID: 32843303.
    Citations: 3     Fields:    
  48. Baslet G, Bajestan SN, Aybek S, Modirrousta M, D Clin Psy JP, Cavanna A, Perez DL, Lazarow SS, Raynor G, Voon V, Ducharme S, LaFrance WC. Evidence-Based Practice for the Clinical Assessment of Psychogenic Nonepileptic Seizures: A Report From the American Neuropsychiatric Association Committee on Research. J Neuropsychiatry Clin Neurosci. 2021; 33(1):27-42. PMID: 32778006.
    Citations: 9     Fields:    Translation:Humans
  49. Perez DL, Aybek S, Popkirov S, Kozlowska K, Stephen CD, Anderson J, Shura R, Ducharme S, Carson A, Hallett M, Nicholson TR, Stone J, LaFrance WC, Voon V. A Review and Expert Opinion on the Neuropsychiatric Assessment of Motor Functional Neurological Disorders. J Neuropsychiatry Clin Neurosci. 2021; 33(1):14-26. PMID: 32778007.
    Citations: 12     Fields:    Translation:Humans
  50. Perez DL. Persistence of the 'broken escalator' phenomenon in functional gait disorder: mechanistic insights. Brain. 2020 08 01; 143(8):2338-2340. PMID: 32844193.
    Citations:    Fields:    Translation:Humans
  51. Asadi-Pooya AA, Nicholson TR, Pick S, Baslet G, Benbadis SR, Beghi M, Brigo F, Buchhalter J, D'Alessio L, Dworetzky B, Gigineishvili D, Kanaan RA, Kozlowska K, LaFrance WC, Lehn A, Perez DL, Popkirov S, Pretorius C, Szaflarski JP, Tolchin B, Valente K, Stone J, Reuber M. Driving a motor vehicle and psychogenic nonepileptic seizures: ILAE Report by the Task Force on Psychogenic Nonepileptic Seizures. Epilepsia Open. 2020 Sep; 5(3):371-385. PMID: 32913946; PMCID: PMC7469780.
    Citations: 1     Fields:    
  52. Alluri PR, Solit J, Leveroni CL, Goldberg K, Vehar JV, Pollak LE, Colvin MK, Perez DL. Cognitive Complaints in Motor Functional Neurological (Conversion) Disorders: A Focused Review and Clinical Perspective. Cogn Behav Neurol. 2020 06; 33(2):77-89. PMID: 32496293.
    Citations: 6     Fields:    Translation:Humans
  53. Perez DL. The CODES trial for dissociative seizures: a landmark study and inflection point. Lancet Psychiatry. 2020 06; 7(6):464-465. PMID: 32445672.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  54. Pick S, Anderson DG, Asadi-Pooya AA, Aybek S, Baslet G, Bloem BR, Bradley-Westguard A, Brown RJ, Carson AJ, Chalder T, Damianova M, David AS, Edwards MJ, Epstein SA, Espay AJ, Garcin B, Goldstein LH, Hallett M, Jankovic J, Joyce EM, Kanaan RA, Keynejad RC, Kozlowska K, LaFaver K, LaFrance WC, Lang AE, Lehn A, Lidstone S, Maurer CW, Mildon B, Morgante F, Myers L, Nicholson C, Nielsen G, Perez DL, Popkirov S, Reuber M, Rommelfanger KS, Schwingenshuh P, Serranova T, Shotbolt P, Stebbins GT, Stone J, Tijssen MA, Tinazzi M, Nicholson TR. Outcome measurement in functional neurological disorder: a systematic review and recommendations. J Neurol Neurosurg Psychiatry. 2020 06; 91(6):638-649. PMID: 32111637.
    Citations: 19     Fields:    Translation:Humans
  55. Ranford J, MacLean J, Alluri PR, Comeau O, Godena E, LaFrance WC, Hunt A, Stephen CD, Perez DL. Sensory Processing Difficulties in Functional Neurological Disorder: A Possible Predisposing Vulnerability? Psychosomatics. 2020 Jul - Aug; 61(4):343-352. PMID: 32284249.
    Citations: 3     Fields:    Translation:Humans
  56. Diez I, Larson AG, Nakhate V, Dunn EC, Fricchione GL, Nicholson TR, Sepulcre J, Perez DL. Early-life trauma endophenotypes and brain circuit-gene expression relationships in functional neurological (conversion) disorder. Mol Psychiatry. 2021 08; 26(8):3817-3828. PMID: 32051548; PMCID: PMC7423688.
    Citations: 13     Fields:    Translation:Humans
  57. Perez DL, Aybek S, Nicholson TR, Kozlowska K, Arciniegas DB, LaFrance WC. Functional Neurological (Conversion) Disorder: A Core Neuropsychiatric Disorder. J Neuropsychiatry Clin Neurosci. 2020 Winter; 32(1):1-3. PMID: 31964243.
    Citations: 2     Fields:    Translation:Humans
  58. Nicholson TR, Carson A, Edwards MJ, Goldstein LH, Hallett M, Mildon B, Nielsen G, Nicholson C, Perez DL, Pick S, Stone J. Outcome Measures for Functional Neurological Disorder: A Review of the Theoretical Complexities. J Neuropsychiatry Clin Neurosci. 2020; 32(1):33-42. PMID: 31865871.
    Citations: 17     Fields:    Translation:Humans
  59. Perez DL, Mark VW, Stone J. Neuroimaging of US Government Personnel Exposed to Directional Phenomena. JAMA. 2019 12 10; 322(22):2249. PMID: 31821426.
    Citations:    Fields:    
  60. Diez I, Williams B, Kubicki MR, Makris N, Perez DL. Reduced limbic microstructural integrity in functional neurological disorder. Psychol Med. 2021 02; 51(3):485-493. PMID: 31769368; PMCID: PMC7247956.
    Citations: 8     Fields:    Translation:Humans
  61. Khachane Y, Kozlowska K, Savage B, McClure G, Butler G, Gray N, Worth A, Mihailovich S, Perez DL, Helgeland H, Chrousos GP. Twisted in Pain: The Multidisciplinary Treatment Approach to Functional Dystonia. Harv Rev Psychiatry. 2019 Nov/Dec; 27(6):359-381. PMID: 31714467; PMCID: PMC6867659.
    Citations: 3     Fields:    Translation:Humans
  62. Maggio JB, Ospina JP, Callahan J, Hunt AL, Stephen CD, Perez DL. Outpatient Physical Therapy for Functional Neurological Disorder: A Preliminary Feasibility and Naturalistic Outcome Study in a U.S. Cohort. J Neuropsychiatry Clin Neurosci. 2020; 32(1):85-89. PMID: 31564236.
    Citations: 4     Fields:    Translation:Humans
  63. Xin Q, Ortiz-Terán L, Diez I, Perez DL, Ginsburg J, El Fakhri G, Sepulcre J. Sequence Alterations of Cortical Genes Linked to Individual Connectivity of the Human Brain. Cereb Cortex. 2019 08 14; 29(9):3828-3835. PMID: 30307489.
    Citations: 5     Fields:    Translation:HumansCells
  64. Ospina JP, Larson AG, Jalilianhasanpour R, Williams B, Diez I, Dhand A, Dickerson BC, Perez DL. Individual differences in social network size linked to nucleus accumbens and hippocampal volumes in functional neurological disorder: A pilot study. J Affect Disord. 2019 11 01; 258:50-54. PMID: 31394458.
    Citations: 4     Fields:    Translation:Humans
  65. Popkirov S, Nicholson TR, Bloem BR, Cock HR, Derry CP, Duncan R, Dworetzky BA, Edwards MJ, Espay AJ, Hallett M, Lang AE, Leach JP, Lehn A, McGonigal A, Morgante F, Perez DL, Reuber M, Richardson MP, Smith P, Stamelou M, Tijssen MAJ, Tinazzi M, Carson AJ, Stone J. Hiding in Plain Sight: Functional Neurological Disorders in the News. J Neuropsychiatry Clin Neurosci. 2019; 31(4):361-367. PMID: 31117907; PMCID: PMC7291360.
    Citations: 2     Fields:    Translation:Humans
  66. Perez DL, Haller AL, Espay AJ. Should neurologists diagnose and manage functional neurologic disorders? It is complicated. Neurol Clin Pract. 2019 Apr; 9(2):165-167. PMID: 31041133; PMCID: PMC6461419.
    Citations: 3     
  67. Bègue I, Adams C, Stone J, Perez DL. Structural alterations in functional neurological disorder and related conditions: a software and hardware problem? Neuroimage Clin. 2019; 22:101798. PMID: 31146322; PMCID: PMC6484222.
    Citations: 19     Fields:    Translation:Humans
  68. Diez I, Ortiz-Terán L, Williams B, Jalilianhasanpour R, Ospina JP, Dickerson BC, Keshavan MS, LaFrance WC, Sepulcre J, Perez DL. Corticolimbic fast-tracking: enhanced multimodal integration in functional neurological disorder. J Neurol Neurosurg Psychiatry. 2019 08; 90(8):929-938. PMID: 30850473; PMCID: PMC6625895.
    Citations: 17     Fields:    Translation:Humans
  69. Anderson JR, Nakhate V, Stephen CD, Perez DL. Functional (Psychogenic) Neurological Disorders: Assessment and Acute Management in the Emergency Department. Semin Neurol. 2019 Feb; 39(1):102-114. PMID: 30743296.
    Citations: 5     Fields:    Translation:Humans
  70. Ospina JP, Jalilianhasanpour R, Perez DL. The role of the anterior and midcingulate cortex in the neurobiology of functional neurologic disorder. Handb Clin Neurol. 2019; 166:267-279. PMID: 31731915; PMCID: PMC7012371.
    Citations: 5     Fields:    Translation:Humans
  71. Pick S, Goldstein LH, Perez DL, Nicholson TR. Emotional processing in functional neurological disorder: a review, biopsychosocial model and research agenda. J Neurol Neurosurg Psychiatry. 2019 06; 90(6):704-711. PMID: 30455406; PMCID: PMC6525039.
    Citations: 42     Fields:    Translation:Humans
  72. Williams B, Ospina JP, Jalilianhasanpour R, Fricchione GL, Perez DL. Fearful Attachment Linked to Childhood Abuse, Alexithymia, and Depression in Motor Functional Neurological Disorders. J Neuropsychiatry Clin Neurosci. 2019; 31(1):65-69. PMID: 30376786; PMCID: PMC6349486.
    Citations: 8     Fields:    Translation:Humans
  73. Jalilianhasanpour R, Ospina JP, Williams B, Mello J, MacLean J, Ranford J, Fricchione GL, LaFrance WC, Perez DL. Secure Attachment and Depression Predict 6-Month Outcome in Motor Functional Neurological Disorders: A Prospective Pilot Study. Psychosomatics. 2019 Jul - Aug; 60(4):365-375. PMID: 30342702.
    Citations: 4     Fields:    Translation:Humans
  74. Perez DL, Keshavan MS, Scharf JM, Boes AD, Price BH. Bridging the Great Divide: What Can Neurology Learn From Psychiatry? J Neuropsychiatry Clin Neurosci. 2018; 30(4):271-278. PMID: 29939105; PMCID: PMC6309772.
    Citations: 7     Fields:    Translation:Humans
  75. Ranford J, Perez DL, MacLean J. Additional occupational therapy considerations for functional neurological disorders: a potential role for sensory processing. CNS Spectr. 2018 06; 23(3):194-195. PMID: 29781409.
    Citations: 3     Fields:    Translation:Humans
  76. Adams C, Anderson J, Madva EN, LaFrance WC, Perez DL. You've made the diagnosis of functional neurological disorder: now what? Pract Neurol. 2018 Aug; 18(4):323-330. PMID: 29764988; PMCID: PMC6372294.
    Citations: 11     Fields:    Translation:Humans
  77. Williams B, Jalilianhasanpour R, Matin N, Fricchione GL, Sepulcre J, Keshavan MS, LaFrance WC, Dickerson BC, Perez DL. Individual differences in corticolimbic structural profiles linked to insecure attachment and coping styles in motor functional neurological disorders. J Psychiatr Res. 2018 07; 102:230-237. PMID: 29702433.
    Citations: 8     Fields:    Translation:Humans
  78. Peterson KT, Kosior R, Meek BP, Ng M, Perez DL, Modirrousta M. Right Temporoparietal Junction Transcranial Magnetic Stimulation in the Treatment of Psychogenic Nonepileptic Seizures: A Case Series. Psychosomatics. 2018 11; 59(6):601-606. PMID: 29628295; PMCID: PMC6128773.
    Citations: 3     Fields:    Translation:Humans
  79. Jalilianhasanpour R, Williams B, Gilman I, Burke MJ, Glass S, Fricchione GL, Keshavan MS, LaFrance WC, Perez DL. Resilience linked to personality dimensions, alexithymia and affective symptoms in motor functional neurological disorders. J Psychosom Res. 2018 04; 107:55-61. PMID: 29502765.
    Citations: 9     Fields:    Translation:Humans
  80. Perez DL, Williams B, Matin N, Mello J, Dickerson BC, LaFrance WC, Keshavan MS. Anterior hippocampal grey matter predicts mental health outcome in functional neurological disorders: an exploratory pilot study. J Neurol Neurosurg Psychiatry. 2018 11; 89(11):1221-1224. PMID: 29326291; PMCID: PMC6041189.
    Citations: 6     Fields:    Translation:Humans
  81. McKee K, Glass S, Adams C, Stephen CD, King F, Parlman K, Perez DL, Kontos N. The Inpatient Assessment and Management of Motor Functional Neurological Disorders: An Interdisciplinary Perspective. Psychosomatics. 2018 Jul - Aug; 59(4):358-368. PMID: 29628294.
    Citations: 7     Fields:    Translation:Humans
  82. Glass SP, Matin N, Williams B, Mello J, Stephen CD, Young SS, Callahan J, LaFrance WC, Perez DL. Neuropsychiatric Factors Linked to Adherence and Short-Term Outcome in a U.S. Functional Neurological Disorders Clinic: A Retrospective Cohort Study. J Neuropsychiatry Clin Neurosci. 2018; 30(2):152-159. PMID: 29132273.
    Citations: 7     Fields:    Translation:Humans
  83. Perez DL, Matin N, Williams B, Tanev K, Makris N, LaFrance WC, Dickerson BC. Cortical thickness alterations linked to somatoform and psychological dissociation in functional neurological disorders. Hum Brain Mapp. 2018 01; 39(1):428-439. PMID: 29080235.
    Citations: 20     Fields:    Translation:Humans
  84. Stephen CD, Sharma N, Callahan J, Carson AJ, Perez DL. A Case of Functional Dystonia with Associated Functional Neurological Symptoms: Diagnostic and Therapeutic Challenges. Harv Rev Psychiatry. 2017 Sep/Oct; 25(5):241-251. PMID: 28650853.
    Citations: 4     Fields:    Translation:Humans
  85. Perez DL, Williams B, Matin N, LaFrance WC, Costumero-Ramos V, Fricchione GL, Sepulcre J, Keshavan MS, Dickerson BC. Corticolimbic structural alterations linked to health status and trait anxiety in functional neurological disorder. J Neurol Neurosurg Psychiatry. 2017 12; 88(12):1052-1059. PMID: 28844071.
    Citations: 22     Fields:    Translation:Humans
  86. Perez DL, Voon V. Psychogenic Nonepileptic Seizures: Toward the Integration of Care. The Neurobiology of PNES and Other Functional Neurological Symptoms. 2017.
  87. Chandra P, Kozlowska K, Cruz C, Baslet GC, Perez DL, Garralda ME. Hyperventilation-Induced Non-epileptic Seizures in an Adolescent Boy with Pediatric Medical Traumatic Stress. Harv Rev Psychiatry. 2017 Jul/Aug; 25(4):180-190. PMID: 28471819.
    Citations: 3     Fields:    Translation:Humans
  88. Ortiz-Terán L, Diez I, Ortiz T, Perez DL, Aragón JI, Costumero V, Pascual-Leone A, El Fakhri G, Sepulcre J. Brain circuit-gene expression relationships and neuroplasticity of multisensory cortices in blind children. Proc Natl Acad Sci U S A. 2017 06 27; 114(26):6830-6835. PMID: 28607055; PMCID: PMC5495230.
    Citations: 14     Fields:    Translation:HumansCTClinical Trials
  89. Matin N, Young SS, Williams B, LaFrance WC, King JN, Caplan D, Chemali Z, Weilburg JB, Dickerson BC, Perez DL. Neuropsychiatric Associations With Gender, Illness Duration, Work Disability, and Motor Subtype in a U.S. Functional Neurological Disorders Clinic Population. J Neuropsychiatry Clin Neurosci. 2017; 29(4):375-382. PMID: 28449634.
    Citations: 8     Fields:    Translation:Humans
  90. Perez DL, Matin N, Barsky A, Costumero-Ramos V, Makaretz SJ, Young SS, Sepulcre J, LaFrance WC, Keshavan MS, Dickerson BC. Cingulo-insular structural alterations associated with psychogenic symptoms, childhood abuse and PTSD in functional neurological disorders. J Neurol Neurosurg Psychiatry. 2017 06; 88(6):491-497. PMID: 28416565; PMCID: PMC5497745.
    Citations: 32     Fields:    Translation:Humans
  91. Perez DL, Young SS, King JN, Guarino AJ, Dworetzky BA, Flaherty A, Chemali Z, Caplan D, Dickerson BC. Preliminary Predictors of Initial Attendance, Symptom Burden, and Motor Subtype in a US Functional Neurological Disorders Clinic Population. Cogn Behav Neurol. 2016 Dec; 29(4):197-205. PMID: 27984257.
    Citations: 7     Fields:    Translation:Humans
  92. Perez D, Eldaief, M, Epstein J, Silbersweig D, Stern E. Depression in Medical Illness. The Neurobiology of Depression: An Integrated Systems-Level, Cellular–Molecular and Genetic Overview. 2016.
  93. Ortiz-Terán L, Ortiz T, Perez DL, Aragón JI, Diez I, Pascual-Leone A, Sepulcre J. Brain Plasticity in Blind Subjects Centralizes Beyond the Modal Cortices. Front Syst Neurosci. 2016; 10:61. PMID: 27458350; PMCID: PMC4937754.
    Citations: 9     
  94. Perez DL, Torous J, Stern AP, Padmanabhan JL, Keshavan MS. Response to "Tandon et al. Psychiatry is a clinical neuroscience, but how do we move the field". Asian J Psychiatr. 2016 Aug; 22:15-6. PMID: 27520888.
    Citations:    Fields:    Translation:Humans
  95. Perez DL, LaFrance WC. Nonepileptic seizures: an updated review. CNS Spectr. 2016 Jun; 21(3):239-46. PMID: 26996600.
    Citations: 30     Fields:    Translation:Humans
  96. Fischer DB, Perez DL, Prasad S, Rigolo L, O'Donnell L, Acar D, Meadows ME, Baslet G, Boes AD, Golby AJ, Dworetzky BA. Right inferior longitudinal fasciculus lesions disrupt visual-emotional integration. Soc Cogn Affect Neurosci. 2016 06; 11(6):945-51. PMID: 26940563.
    Citations: 6     Fields:    Translation:Humans
  97. Perez DL, Murray ED, Price BH. Bradley's Neurology in Clinical Practice - 7th Edition. Chapter 10: Depression and Psychosis in Neurological Practice. 2016; 92-114.
  98. Perez DL, Vago DR, Pan H, Root J, Tuescher O, Fuchs BH, Leung L, Epstein J, Cain NM, Clarkin JF, Lenzenweger MF, Kernberg OF, Levy KN, Silbersweig DA, Stern E. Frontolimbic neural circuit changes in emotional processing and inhibitory control associated with clinical improvement following transference-focused psychotherapy in borderline personality disorder. Psychiatry Clin Neurosci. 2016 Jan; 70(1):51-61. PMID: 26289141; PMCID: PMC4718821.
    Citations: 18     Fields:    Translation:HumansCTClinical Trials
  99. Perez DL, Pan H, Weisholtz DS, Root JC, Tuescher O, Fischer DB, Butler T, Vago DR, Isenberg N, Epstein J, Landa Y, Smith TE, Savitz AJ, Silbersweig DA, Stern E. Altered threat and safety neural processing linked to persecutory delusions in schizophrenia: a two-task fMRI study. Psychiatry Res. 2015 Sep 30; 233(3):352-66. PMID: 26208746.
    Citations: 11     Fields:    Translation:Humans
  100. Torous J, Stern AP, Padmanabhan JL, Keshavan MS, Perez DL. A proposed solution to integrating cognitive-affective neuroscience and neuropsychiatry in psychiatry residency training: The time is now. Asian J Psychiatr. 2015 Oct; 17:116-21. PMID: 26054985.
    Citations: 6     Fields:    Translation:Humans
  101. Perez DL, Ortiz Teran L, Silbersweig DA. In: Psychiatric Care of the Medical Patient. Edited by Fogel BS, Greenberg DB. Neuroimaging in Psychiatry: The Clinical Radiographic Correlate. 2015; 137-154.
  102. Baslet G, Dworetzky BA, Perez DL. Psychogenic nonepileptic seizures: a new direction. Clin EEG Neurosci. 2015 Jan; 46(1):3. PMID: 25780263.
    Citations:    Fields:    
  103. Reinsberger C, Sarkis R, Papadelis C, Doshi C, Perez DL, Baslet G, Loddenkemper T, Dworetzky BA. Autonomic changes in psychogenic nonepileptic seizures: toward a potential diagnostic biomarker? Clin EEG Neurosci. 2015 Jan; 46(1):16-25. PMID: 25780264.
    Citations: 8     Fields:    Translation:Humans
  104. Dworetzky BA, Weisholtz DS, Perez DL, Baslet G. A clinically oriented perspective on psychogenic nonepileptic seizure-related emergencies. Clin EEG Neurosci. 2015 Jan; 46(1):26-33. PMID: 25780265.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  105. Baslet G, Dworetzky B, Perez DL, Oser M. Treatment of psychogenic nonepileptic seizures: updated review and findings from a mindfulness-based intervention case series. Clin EEG Neurosci. 2015 Jan; 46(1):54-64. PMID: 25465435.
    Citations: 11     Fields:    Translation:Humans
  106. Perez DL, Dworetzky BA, Dickerson BC, Leung L, Cohn R, Baslet G, Silbersweig DA. An integrative neurocircuit perspective on psychogenic nonepileptic seizures and functional movement disorders: neural functional unawareness. Clin EEG Neurosci. 2015 Jan; 46(1):4-15. PMID: 25432161.
    Citations: 39     Fields:    Translation:Humans
  107. Perez DL, Barsky AJ, Vago DR, Baslet G, Silbersweig DA. A neural circuit framework for somatosensory amplification in somatoform disorders. J Neuropsychiatry Clin Neurosci. 2015; 27(1):e40-50. PMID: 25716493.
    Citations: 25     Fields:    Translation:Humans
  108. Perez DL, Fuchs BH, Epstein J. A case of cotard syndrome in a woman with a right subdural hemorrhage. J Neuropsychiatry Clin Neurosci. 2014; 26(1):E29-30. PMID: 24515701.
    Citations: 3     Fields:    Translation:Humans
  109. Cho-Park YA, Perez DL, Milligan TA, Cho PF. Radiographic evolution of a rapidly reversible leukoencephalopathy due to metronidazole. Neurol Clin Pract. 2013 Jun; 3(3):272-274. PMID: 29473640; PMCID: PMC5798518.
    Citations: 1     
  110. Biswas J, Chu JA, Perez DL, Gutheil TG. From the neuropsychiatric to the analytic: three perspectives on dissociative identity disorder. Harv Rev Psychiatry. 2013 Jan-Feb; 21(1):41-51. PMID: 23656761.
    Citations: 1     Fields:    Translation:Humans
  111. Perez DL, Hunt P, Trieu M. A case of dual dissociative and re-experiencing/hyperarousal subtypes in childhood PTSD: a neuropsychiatric formulation. J Neuropsychiatry Clin Neurosci. 2013; 25(1):E24-5. PMID: 23487216.
    Citations: 1     Fields:    Translation:Humans
  112. Perez DL, Dickerson BC, McGinnis SM, Sapolsky D, Johnson K, Searl M, Daffner KR. You don't say: dynamic aphasia, another variant of primary progressive aphasia? J Alzheimers Dis. 2013; 34(1):139-44. PMID: 23168447.
    Citations: 4     Fields:    Translation:Humans
  113. Perez DL, Barsky AJ, Daffner K, Silbersweig DA. Motor and somatosensory conversion disorder: a functional unawareness syndrome? J Neuropsychiatry Clin Neurosci. 2012; 24(2):141-51. PMID: 22772662.
    Citations: 14     Fields:    Translation:Humans
  114. Reinsberger C, Perez DL, Murphy MM, Dworetzky BA. Pre- and postictal, not ictal, heart rate distinguishes complex partial and psychogenic nonepileptic seizures. Epilepsy Behav. 2012 Jan; 23(1):68-70. PMID: 22100065.
    Citations: 15     Fields:    Translation:Humans
  115. Perez DL, Larvie M, Acar D, Daffner K. Teaching NeuroImages: apathetic variant of frontotemporal dementia. Neurology. 2011 Nov 15; 77(20):e117. PMID: 22084280.
    Citations: 1     Fields:    Translation:Humans
  116. Perez DL, Catenaccio E, Epstein J. Journal of Neurology and Neurophysiology. Confusion, Hyperactive Delirium, and Secondary Mania in Right Hemispheric Strokes: A Focused Review of Neuroanatomical Correlates. 2011. View Publication.
  117. Epstein J, Perez DL, Ervin K, Pan H, Kocsis JH, Butler T, Stern E, Silbersweig DA. Failure to segregate emotional processing from cognitive and sensorimotor processing in major depression. Psychiatry Res. 2011 Sep 30; 193(3):144-50. PMID: 21764265.
    Citations: 10     Fields:    Translation:Humans
  118. Woolley AG, Algie M, Samuel W, Harfoot R, Wiles A, Hung NA, Tan PH, Hains P, Valova VA, Huschtscha L, Royds JA, Perez D, Yoon HS, Cohen SB, Robinson PJ, Bay BH, Lasham A, Braithwaite AW. Prognostic association of YB-1 expression in breast cancers: a matter of antibody. PLoS One. 2011; 6(6):e20603. PMID: 21695211; PMCID: PMC3112203.
    Citations: 16     Fields:    Translation:HumansCells
  119. Benbadis SR. Teaching Video NeuroImages: complex partial seizure evolving into a psychogenic nonepileptic seizure. Neurology. 2011 May 10; 76(19):1681; author reply 1681. PMID: 21555740.
    Citations:    Fields:    Translation:Humans
  120. Espinosa PS, Perez DL, Abner E, Ryan M. Association of antiepileptic drugs, vitamin D, and calcium supplementation with bone fracture occurrence in epilepsy patients. Clin Neurol Neurosurg. 2011 Sep; 113(7):548-51. PMID: 21507568.
    Citations: 5     Fields:    Translation:Humans
  121. Perez DL, Haldar A, Rotenberg A, Kothare SV. Teaching Video NeuroImages: complex partial seizure evolving into a psychogenic nonepileptic seizure. Neurology. 2010 Dec 14; 75(24):e98. PMID: 21172839.
    Citations: 1     Fields:    Translation:Humans
  122. Perez DL, Diamond EL, Castro CM, Diaz A, Buonanno F, Nogueira RG, Sheth K. Factor XIII deficiency related recurrent spontaneous intracerebral hemorrhage: a case and literature review. Clin Neurol Neurosurg. 2011 Feb; 113(2):142-5. PMID: 20950938.
    Citations: 2     Fields:    Translation:Humans
  123. Pollak DD, Rogan MT, Egner T, Perez DL, Yanagihara TK, Hirsch J. A translational bridge between mouse and human models of learned safety. Ann Med. 2010 Mar; 42(2):115-22. PMID: 20121549.
    Citations: 27     Fields:    Translation:HumansAnimals
  124. Rogan MT, Leon KS, Perez DL, Kandel ER. Distinct neural signatures for safety and danger in the amygdala and striatum of the mouse. Neuron. 2005 Apr 21; 46(2):309-20. PMID: 15848808.
    Citations: 101     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.