Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles

Turgay Dalkara, PH.D., M.D.

Title
Institution
Department
Address
Phone
Fax

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Yapici-Eser H, Dönmez-Demir B, Kiliç K, Eren-Koçak E, Dalkara T. Stress modulates cortical excitability via a-2 adrenergic and glucocorticoid receptors: As assessed by spreading depression. Exp Neurol. 2018 Sep; 307:45-51. PMID: 29856967.
    View in: PubMed
  2. Dönmez-Demir B, Yemisci M, Dalkara T. Data of ascending cortical vein occlusion induced spreading depression. Data Brief. 2018 Jun; 18:1462-1465. PMID: 29900326.
    View in: PubMed
  3. Taskiran-Sag A, Yemisci M, Gursoy-Ozdemir Y, Erdener SE, Karatas H, Yuce D, Dalkara T. Improving Microcirculatory Reperfusion Reduces Parenchymal Oxygen Radical Formation and Provides Neuroprotection. Stroke. 2018 May; 49(5):1267-1275. PMID: 29669868.
    View in: PubMed
  4. Alarcon-Martinez L, Yilmaz-Ozcan S, Yemisci M, Schallek J, Kiliç K, Can A, Di Polo A, Dalkara T. Capillary pericytes express a-smooth muscle actin, which requires prevention of filamentous-actin depolymerization for detection. Elife. 2018 Mar 21; 7. PMID: 29561727.
    View in: PubMed
  5. Yemisci M, Caban S, Fernandez-Megia E, Capan Y, Couvreur P, Dalkara T. Preparation and Characterization of Biocompatible Chitosan Nanoparticles for Targeted Brain Delivery of Peptides. Methods Mol Biol. 2018; 1727:443-454. PMID: 29222804.
    View in: PubMed
  6. Kilic K, Karatas H, Dönmez-Demir B, Eren-Kocak E, Gursoy-Ozdemir Y, Can A, Petit JM, Magistretti PJ, Dalkara T. Inadequate brain glycogen or sleep increases spreading depression susceptibility. Ann Neurol. 2018 Jan; 83(1):61-73. PMID: 29244233.
    View in: PubMed
  7. Cambray S, Portero-Otin M, Jové M, Torreguitart N, Colàs-Campàs L, Sanz A, Benabdelhak I, Yemisci M, Dalkara T, Dönmez-Demir B, Egea J, Purroy F. Metabolomic Estimation of the Diagnosis and Onset Time of Permanent and Transient Cerebral Ischemia. Mol Neurobiol. 2018 Jul; 55(7):6193-6200. PMID: 29270918.
    View in: PubMed
  8. Dönmez-Demir B, Yemisci M, Kiliç K, Gürsoy-Özdemir Y, Söylemezoglu F, Moskowitz M, Dalkara T. Microembolism of single cortical arterioles can induce spreading depression and ischemic injury; a potential trigger for migraine and related MRI lesions. Brain Res. 2018 01 15; 1679:84-90. PMID: 29183666.
    View in: PubMed
  9. Seyrantepe V, Demir SA, Timur ZK, Von Gerichten J, Marsching C, Erdemli E, Oztas E, Takahashi K, Yamaguchi K, Ates N, Dönmez Demir B, Dalkara T, Erich K, Hopf C, Sandhoff R, Miyagi T. Murine Sialidase Neu3 facilitates GM2 degradation and bypass in mouse model of Tay-Sachs disease. Exp Neurol. 2018 01; 299(Pt A):26-41. PMID: 28974375.
    View in: PubMed
  10. Colpak AI, Balci-Peynircioglu B, Can A, Gursoy-Ozdemir Y, Lule S, Kalyoncu U, Dalkara T. Data of indirect immunofluorescence labeling of the mouse brain sections with sera from SLE and MS patients. Data Brief. 2017 Dec; 15:170-173. PMID: 29034286.
    View in: PubMed
  11. Lule S, Colpak AI, Balci-Peynircioglu B, Gursoy-Ozdemir Y, Peker S, Kalyoncu U, Can A, Tekin N, Demiralp D, Dalkara T. Behçet Disease serum is immunoreactive to neurofilament medium which share common epitopes to bacterial HSP-65, a putative trigger. J Autoimmun. 2017 Nov; 84:87-96. PMID: 28844827.
    View in: PubMed
  12. Arsava EM, Arat A, Topcuoglu MA, Peker A, Yemisci M, Dalkara T. Angiographic Microcirculatory Obstructions Distal to Occlusion Signify Poor Outcome after Endovascular Treatment for Acute Ischemic Stroke. Transl Stroke Res. 2018 02; 9(1):44-50. PMID: 28825223.
    View in: PubMed
  13. Lee J, Gursoy-Ozdemir Y, Fu B, Boas DA, Dalkara T. Optical coherence tomography imaging of capillary reperfusion after ischemic stroke. Appl Opt. 2016 Nov 20; 55(33):9526-9531. PMID: 27869849.
    View in: PubMed
  14. Kutluk K, Kaya D, Afsar N, Arsava EM, Ozturk V, Uzuner N, Giray S, Topcuoglu MA, Gungor L, Sirin H, Yaka E, Ozdemir O, Dalkara T. Analyses of the Turkish National Intravenous Thrombolysis Registry. J Stroke Cerebrovasc Dis. 2016 May; 25(5):1041-1047. PMID: 26853139.
    View in: PubMed
  15. Østergaard L, Engedal TS, Moreton F, Hansen MB, Wardlaw JM, Dalkara T, Markus HS, Muir KW. Cerebral small vessel disease: Capillary pathways to stroke and cognitive decline. J Cereb Blood Flow Metab. 2016 Feb; 36(2):302-25. PMID: 26661176.
    View in: PubMed
  16. Attwell D, Mishra A, Hall CN, O'Farrell FM, Dalkara T. What is a pericyte? J Cereb Blood Flow Metab. 2016 Feb; 36(2):451-5. PMID: 26661200; PMCID: PMC4759679 [Available on 02/01/17].
  17. Østergaard L, Dreier JP, Hadjikhani N, Jespersen SN, Dirnagl U, Dalkara T. Neurovascular coupling during cortical spreading depolarization and -depression. Stroke. 2015 May; 46(5):1392-401. PMID: 25882051.
    View in: PubMed
  18. Dalkara T, Alarcon-Martinez L. Cerebral microvascular pericytes and neurogliovascular signaling in health and disease. Brain Res. 2015 Oct 14; 1623:3-17. PMID: 25862573.
    View in: PubMed
  19. Gaudin A, Yemisci M, Eroglu H, Lepetre-Mouelhi S, Turkoglu OF, Dönmez-Demir B, Caban S, Sargon MF, Garcia-Argote S, Pieters G, Loreau O, Rousseau B, Tagit O, Hildebrandt N, Dantec YL, Mougin J, Valetti S, Chacun H, Nicolas V, Desmaële D, Andrieux K, Capan Y, Dalkara T, Couvreur P. Erratum: Squalenoyl adenosine nanoparticles provide neuroprotection after stroke and spinal cord injury. Nat Nanotechnol. 2015 Jan; 10(1):99. PMID: 25559969.
    View in: PubMed
  20. Yemisci M, Caban S, Gursoy-Ozdemir Y, Lule S, Novoa-Carballal R, Riguera R, Fernandez-Megia E, Andrieux K, Couvreur P, Capan Y, Dalkara T. Systemically administered brain-targeted nanoparticles transport peptides across the blood-brain barrier and provide neuroprotection. J Cereb Blood Flow Metab. 2015 Mar; 35(3):469-75. PMID: 25492116; PMCID: PMC4348388.
  21. Yildirim T, Eylen A, Lule S, Erdener SE, Vural A, Karatas H, Ozveren MF, Dalkara T, Gursoy-Ozdemir Y. Poloxamer-188 and citicoline provide neuronal membrane integrity and protect membrane stability in cortical spreading depression. Int J Neurosci. 2015; 125(12):941-6. PMID: 25340256.
    View in: PubMed
  22. Gaudin A, Yemisci M, Eroglu H, Lepetre-Mouelhi S, Turkoglu OF, Dönmez-Demir B, Caban S, Sargon MF, Garcia-Argote S, Pieters G, Loreau O, Rousseau B, Tagit O, Hildebrandt N, Le Dantec Y, Mougin J, Valetti S, Chacun H, Nicolas V, Desmaële D, Andrieux K, Capan Y, Dalkara T, Couvreur P. Squalenoyl adenosine nanoparticles provide neuroprotection after stroke and spinal cord injury. Nat Nanotechnol. 2014 Nov 24; 9(12):1054-1062. PMID: 25420034.
    View in: PubMed
  23. Erdener SE, Dalkara T. Modelling headache and migraine and its pharmacological manipulation. Br J Pharmacol. 2014 Oct; 171(20):4575-94. PMID: 24611635; PMCID: PMC4209933.
  24. Kozlu S, Caban S, Yerlikaya F, Fernandez-Megia E, Novoa-Carballal R, Riguera R, Yemisci M, Gursoy-Ozdemir Y, Dalkara T, Couvreur P, Capan Y. An aquaporin 4 antisense oligonucleotide loaded, brain targeted nanoparticulate system design. Pharmazie. 2014 May; 69(5):340-5. PMID: 24855824.
    View in: PubMed
  25. Dalkara T, Kiliç K. How does fasting trigger migraine? A hypothesis. Curr Pain Headache Rep. 2013 Oct; 17(10):368. PMID: 23996724.
    View in: PubMed
  26. Karatas H, Erdener SE, Gursoy-Ozdemir Y, Lule S, Eren-Koçak E, Sen ZD, Dalkara T. Spreading depression triggers headache by activating neuronal Panx1 channels. Science. 2013 Mar 01; 339(6123):1092-5. PMID: 23449592.
    View in: PubMed
  27. Dericioglu N, Soylemezoglu F, Gursoy-Ozdemir Y, Akalan N, Saygi S, Dalkara T. Cell death and survival mechanisms are concomitantly active in the hippocampus of patients with mesial temporal sclerosis. Neuroscience. 2013 May 01; 237:56-65. PMID: 23384610.
    View in: PubMed
  28. Sevgi EB, Erdener SE, Demirci M, Topcuoglu MA, Dalkara T. Paradoxical air microembolism induces cerebral bioelectrical abnormalities and occasionally headache in patent foramen ovale patients with migraine. J Am Heart Assoc. 2012 Dec; 1(6):e001735. PMID: 23316313; PMCID: PMC3540661.
  29. Gursoy-Ozdemir Y, Yemisci M, Dalkara T. Microvascular protection is essential for successful neuroprotection in stroke. J Neurochem. 2012 Nov; 123 Suppl 2:2-11. PMID: 23050637.
    View in: PubMed
  30. Bas DF, Topcuoglu MA, Gursoy-Ozdemir Y, Saatci I, Bodur E, Dalkara T. Plasma 3-nitrotyrosine estimates the reperfusion-induced cerebrovascular stress, whereas matrix metalloproteinases mainly reflect plasma activity: a study in patients treated with thrombolysis or endovascular recanalization. J Neurochem. 2012 Nov; 123 Suppl 2:138-47. PMID: 23050651.
    View in: PubMed
  31. Dalkara T, Arsava EM. Can restoring incomplete microcirculatory reperfusion improve stroke outcome after thrombolysis? J Cereb Blood Flow Metab. 2012 Dec; 32(12):2091-9. PMID: 23047270; PMCID: PMC3519416.
  32. Yemisci M, Gürsoy-Özdemir Y, Caban S, Bodur E, Capan Y, Dalkara T. Transport of a caspase inhibitor across the blood-brain barrier by chitosan nanoparticles. Methods Enzymol. 2012; 508:253-69. PMID: 22449930.
    View in: PubMed
  33. Caban S, Capan Y, Couvreur P, Dalkara T. Preparation and characterization of biocompatible chitosan nanoparticles for targeted brain delivery of peptides. Methods Mol Biol. 2012; 846:321-32. PMID: 22367822.
    View in: PubMed
  34. Dalkara T, Gursoy-Ozdemir Y, Yemisci M. Brain microvascular pericytes in health and disease. Acta Neuropathol. 2011 Jul; 122(1):1-9. PMID: 21656168.
    View in: PubMed
  35. Erdem SR, Emre-Aydingöz S, Atilla P, Cakar AN, Dalkara T, Bolay H, Tuncer M. Cyclosporine A-induced acute hepatotoxicity in guinea pigs is associated with endothelin-mediated decrease in local hepatic blood flow. Life Sci. 2011 Apr 25; 88(17-18):753-60. PMID: 21356218.
    View in: PubMed
  36. Karatas H, Erdener SE, Gursoy-Ozdemir Y, Gurer G, Soylemezoglu F, Dunn AK, Dalkara T. Thrombotic distal middle cerebral artery occlusion produced by topical FeCl(3) application: a novel model suitable for intravital microscopy and thrombolysis studies. J Cereb Blood Flow Metab. 2011 Jun; 31(6):1452-60. PMID: 21326267; PMCID: PMC3130330.
  37. Ertugrul A, Ozdemir H, Vural A, Dalkara T, Meltzer HY, Saka E. The influence of N-desmethylclozapine and clozapine on recognition memory and BDNF expression in hippocampus. Brain Res Bull. 2011 Feb 01; 84(2):144-50. PMID: 21134422.
    View in: PubMed
  38. Unal-Cevik I, Gursoy-Ozdemir Y, Yemisci M, Lule S, Gurer G, Can A, Müller V, Kahle PJ, Dalkara T. Alpha-synuclein aggregation induced by brief ischemia negatively impacts neuronal survival in vivo: a study in [A30P]alpha-synuclein transgenic mouse. J Cereb Blood Flow Metab. 2011 Mar; 31(3):913-23. PMID: 20877387; PMCID: PMC3063624.
  39. Kilinc M, Gürsoy-Ozdemir Y, Gürer G, Erdener SE, Erdemli E, Can A, Dalkara T. Lysosomal rupture, necroapoptotic interactions and potential crosstalk between cysteine proteases in neurons shortly after focal ischemia. Neurobiol Dis. 2010 Oct; 40(1):293-302. PMID: 20600913.
    View in: PubMed
  40. Dalkara T, Nozari A, Moskowitz MA. Migraine aura pathophysiology: the role of blood vessels and microembolisation. Lancet Neurol. 2010 Mar; 9(3):309-17. PMID: 20170844; PMCID: PMC2921876.
  41. Yüzbasioglu A, Karatas H, Gürsoy-Ozdemir Y, Saygi S, Akalan N, Söylemezoglu F, Dalkara T, Kocaefe YC, Ozgüç M. Changes in the expression of selenoproteins in mesial temporal lobe epilepsy patients. Cell Mol Neurobiol. 2009 Dec; 29(8):1223-31. PMID: 19499324.
    View in: PubMed
  42. Karatas H, Aktas Y, Gursoy-Ozdemir Y, Bodur E, Yemisci M, Caban S, Vural A, Pinarbasli O, Capan Y, Fernandez-Megia E, Novoa-Carballal R, Riguera R, Andrieux K, Couvreur P, Dalkara T. A nanomedicine transports a peptide caspase-3 inhibitor across the blood-brain barrier and provides neuroprotection. J Neurosci. 2009 Nov 04; 29(44):13761-9. PMID: 19889988.
    View in: PubMed
  43. Gürer G, Gursoy-Ozdemir Y, Erdemli E, Can A, Dalkara T. Astrocytes are more resistant to focal cerebral ischemia than neurons and die by a delayed necrosis. Brain Pathol. 2009 Oct; 19(4):630-41. PMID: 18947334.
    View in: PubMed
  44. Yemisci M, Gursoy-Ozdemir Y, Vural A, Can A, Topalkara K, Dalkara T. Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery. Nat Med. 2009 Sep; 15(9):1031-7. PMID: 19718040.
    View in: PubMed
  45. Pinarbasli O, Aktas Y, Dalkara T, Andrieux K, Alonso MJ, Fernandez-Megia E, Novoa-Carballal R, Riguera R, Couvreur P, Capan Y. Preparation and evaluation of alpha-phenyl-n-tert-butyl nitrone (PBN)-encapsulated chitosan and PEGylated chitosan nanoparticles. Pharmazie. 2009 Jul; 64(7):436-9. PMID: 19694179.
    View in: PubMed
  46. Yemisçi M, Sinici I, Ozkara HA, Hayran M, Ay H, Celtikçi B, Onder E, Büyükserbetci G, Kaya EB, Tokgözoglu L, Dalkara T. Protective role of 27bp repeat polymorphism in intron 4 of eNOS gene in lacunar infarction. Free Radic Res. 2009 Mar; 43(3):272-9. PMID: 19184759.
    View in: PubMed
  47. Yalcin-Cakmakli G, Akpinar E, Topcuoglu MA, Dalkara T. Right internal carotid artery occlusion during intravenous thrombolysis for left middle cerebral artery occlusion. J Stroke Cerebrovasc Dis. 2009 Jan; 18(1):74-7. PMID: 19110150.
    View in: PubMed
  48. Arsava EM, Gurer G, Gursoy-Ozdemir Y, Karatas H, Dalkara T. A new model of transient focal cerebral ischemia for inducing selective neuronal necrosis. Brain Res Bull. 2009 Mar 16; 78(4-5):226-31. PMID: 19063950.
    View in: PubMed
  49. Yemisci M, Ay H, Kocaefe C, Qui J, Topalkara K, Ozgüç M, Kirazli S, Ozcebe O, Moskowitz MA, Dalkara T. Statin potentiates human platelet eNOS activity without enhancing eNOS mRNA and protein levels. Cerebrovasc Dis. 2008; 26(2):190-8. PMID: 18628618.
    View in: PubMed
  50. Cetin M, Aktas Y, Vural I, Capan Y, Dogan LA, Duman M, Dalkara T. Preparation and in vitro evaluation of bFGF-loaded chitosan nanoparticles. Drug Deliv. 2007 Nov; 14(8):525-9. PMID: 18027182.
    View in: PubMed
  51. Whalen MJ, Dalkara T, You Z, Qiu J, Bermpohl D, Mehta N, Suter B, Bhide PG, Lo EH, Ericsson M, Moskowitz MA. Acute plasmalemma permeability and protracted clearance of injured cells after controlled cortical impact in mice. J Cereb Blood Flow Metab. 2008 Mar; 28(3):490-505. PMID: 17713463; PMCID: PMC2711980.
  52. Cakmak A, Yemisçi M, Köksoy C, Yazgan U, Dinçer D, Dalkara T. Statin pre-treatment protects brain against focal cerebral ischemia in diabetic mice. J Surg Res. 2007 Apr; 138(2):254-8. PMID: 17275846.
    View in: PubMed
  53. Yemisci M, Bozdag S, Cetin M, Söylemezoglu F, Capan Y, Dalkara T, Vural I. Treatment of malignant gliomas with mitoxantrone-loaded poly (lactide-co-glycolide) microspheres. Neurosurgery. 2006 Dec; 59(6):1296-302; discussion 1302-3. PMID: 17277693.
    View in: PubMed
  54. Yemisci M, Bozdag S, Çetin M, Söylemezoglu F, Çapan Y, Dalkara T, Vural I. Treatment Of Malignant Gliomas With Mitoxantrone-Loaded Poly (Lactide-Co-Glycolide) Microspheres. Neurosurgery. 2006 Dec 01; 59(6):1296-1303. PMID: 28180799.
    View in: PubMed
  55. Dalkara T, Zervas NT, Moskowitz MA. From spreading depression to the trigeminovascular system. Neurol Sci. 2006 May; 27 Suppl 2:S86-90. PMID: 16688636.
    View in: PubMed
  56. Ayata C, Jin H, Kudo C, Dalkara T, Moskowitz MA. Suppression of cortical spreading depression in migraine prophylaxis. Ann Neurol. 2006 Apr; 59(4):652-61. PMID: 16450381.
    View in: PubMed
  57. Ozbas-Gerçeker F, Redeker S, Boer K, Ozgüç M, Saygi S, Dalkara T, Soylemezoglu F, Akalan N, Baayen JC, Gorter JA, Aronica E. Serial analysis of gene expression in the hippocampus of patients with mesial temporal lobe epilepsy. Neuroscience. 2006; 138(2):457-74. PMID: 16413123.
    View in: PubMed
  58. Aktas Y, Yemisci M, Andrieux K, Gürsoy RN, Alonso MJ, Fernandez-Megia E, Novoa-Carballal R, Quiñoá E, Riguera R, Sargon MF, Celik HH, Demir AS, Hincal AA, Dalkara T, Capan Y, Couvreur P. Development and brain delivery of chitosan-PEG nanoparticles functionalized with the monoclonal antibody OX26. Bioconjug Chem. 2005 Nov-Dec; 16(6):1503-11. PMID: 16287248.
    View in: PubMed
  59. Kilic AC, Capan Y, Vural I, Gursoy RN, Dalkara T, Cuine A, Hincal AA. Preparation and characterization of PLGA nanospheres for the targeted delivery of NR2B-specific antisense oligonucleotides to the NMDA receptors in the brain. J Microencapsul. 2005 Sep; 22(6):633-41. PMID: 16401579.
    View in: PubMed
  60. Kaya D, Gürsoy-Ozdemir Y, Yemisci M, Tuncer N, Aktan S, Dalkara T. VEGF protects brain against focal ischemia without increasing blood--brain permeability when administered intracerebroventricularly. J Cereb Blood Flow Metab. 2005 Sep; 25(9):1111-8. PMID: 15829918.
    View in: PubMed
  61. Singhal AB, Lo EH, Dalkara T, Moskowitz MA. Advances in stroke neuroprotection: hyperoxia and beyond. Neuroimaging Clin N Am. 2005 Aug; 15(3):697-720, xii-xiii. PMID: 16360598.
    View in: PubMed
  62. Bozdag S, Capan Y, Vural I, Dalkara T, Dogan AL, Guc D, Hincal AA, Deluca PP. In vitro cytotoxicity of mitoxantrone-incorporated albumin microspheres on acute promyelocytic leukaemia cells. J Microencapsul. 2004 Nov; 21(7):751-60. PMID: 15799225.
    View in: PubMed
  63. Ertas M, Siva A, Dalkara T, Uzuner N, Dora B, Inan L, Idiman F, Sarica Y, Selçuki D, Sirin H, Oguzhanoglu A, Irkeç C, Ozmenoglu M, Ozbenli T, Oztürk M, Saip S, Neyal M, Zarifoglu M. Validity and reliability of the Turkish Migraine Disability Assessment (MIDAS) questionnaire. Headache. 2004 Sep; 44(8):786-93. PMID: 15330825.
    View in: PubMed
  64. Unal-Cevik I, Kilinç M, Gürsoy-Ozdemir Y, Gurer G, Dalkara T. Loss of NeuN immunoreactivity after cerebral ischemia does not indicate neuronal cell loss: a cautionary note. Brain Res. 2004 Jul 23; 1015(1-2):169-74. PMID: 15223381.
    View in: PubMed
  65. Unal-Cevik I, Kilinç M, Can A, Gürsoy-Ozdemir Y, Dalkara T. Apoptotic and necrotic death mechanisms are concomitantly activated in the same cell after cerebral ischemia. Stroke. 2004 Sep; 35(9):2189-94. PMID: 15256676.
    View in: PubMed
  66. Müftüoglu M, Elibol B, Dalmizrak O, Ercan A, Kulaksiz G, Ogüs H, Dalkara T, Ozer N. Mitochondrial complex I and IV activities in leukocytes from patients with parkin mutations. Mov Disord. 2004 May; 19(5):544-8. PMID: 15133818.
    View in: PubMed
  67. Gürsoy-Ozdemir Y, Can A, Dalkara T. Reperfusion-induced oxidative/nitrative injury to neurovascular unit after focal cerebral ischemia. Stroke. 2004 Jun; 35(6):1449-53. PMID: 15073398.
    View in: PubMed
  68. Moskowitz MA, Bolay H, Dalkara T. Deciphering migraine mechanisms: clues from familial hemiplegic migraine genotypes. Ann Neurol. 2004 Feb; 55(2):276-80. PMID: 14755732.
    View in: PubMed
  69. Unal Cevik I, Dalkara T. Intravenously administered propidium iodide labels necrotic cells in the intact mouse brain after injury. Cell Death Differ. 2003 Aug; 10(8):928-9. PMID: 12868000.
    View in: PubMed
  70. Uysal H, Cevik IU, Soylemezoglu F, Elibol B, Ozdemir YG, Evrenkaya T, Saygi S, Dalkara T. Is the cell death in mesial temporal sclerosis apoptotic? Epilepsia. 2003 Jun; 44(6):778-84. PMID: 12790890.
    View in: PubMed
  71. Lo EH, Dalkara T, Moskowitz MA. Mechanisms, challenges and opportunities in stroke. Nat Rev Neurosci. 2003 May; 4(5):399-415. PMID: 12728267.
    View in: PubMed
  72. Eckersley P, Egan GF, Amari S, Beltrame F, Bennett R, Bjaalie JG, Dalkara T, De Schutter E, Gonzalez C, Grillner S, Herz A, Hoffmann KP, Jaaskelainen IP, Koslow SH, Lee SY, Matthiessen L, Miller PL, da Silva FM, Novak M, Ravindranath V, Ritz R, Ruotsalainen U, Subramaniam S, Toga AW, Usui S, van Pelt J, Verschure P, Willshaw D, Wrobel A, Tang Y. Neuroscience data and tool sharing: a legal and policy framework for neuroinformatics. Neuroinformatics. 2003; 1(2):149-65. PMID: 15046238.
    View in: PubMed
  73. Amari S, Beltrame F, Bjaalie JG, Dalkara T, De Schutter E, Egan GF, Goddard NH, Gonzalez C, Grillner S, Herz A, Hoffmann KP, Jaaskelainen I, Koslow SH, Lee SY, Matthiessen L, Miller PL, Da Silva FM, Novak M, Ravindranath V, Ritz R, Ruotsalainen U, Sebestra V, Subramaniam S, Tang Y, Toga AW, Usui S, Van Pelt J, Verschure P, Willshaw D, Wrobel A. Neuroinformatics: the integration of shared databases and tools towards integrative neuroscience. J Integr Neurosci. 2002 Dec; 1(2):117-28. PMID: 15011281.
    View in: PubMed
  74. Atalay B, Bolay H, Dalkara T, Soylemezoglu F, Oge K, Ozcan OE. Transcorneal stimulation of trigeminal nerve afferents to increase cerebral blood flow in rats with cerebral vasospasm: a noninvasive method to activate the trigeminovascular reflex. J Neurosurg. 2002 Nov; 97(5):1179-83. PMID: 12450041.
    View in: PubMed
  75. Bolay H, Gürsoy-Ozdemir Y, Sara Y, Onur R, Can A, Dalkara T. Persistent defect in transmitter release and synapsin phosphorylation in cerebral cortex after transient moderate ischemic injury. Stroke. 2002 May; 33(5):1369-75. PMID: 11988617.
    View in: PubMed
  76. Dalkara T. How to construct a research project. Acta Neurochir Suppl. 2002; 83:7-9. PMID: 12442614.
    View in: PubMed
  77. Yilmaz G, Gursoy-Ozdemir Y, Dogan AI, Gurdal H, Gedikoglu G, Dalkara T, Guc MO. Spleen damage in endotoxaemic mice: the involvement of nitric oxide. J Physiol Pharmacol. 2001 Dec; 52(4 Pt 2):729-44. PMID: 11785769.
    View in: PubMed
  78. Unal I, Gürsoy-Ozdemir Y, Bolay H, Söylemezoglu F, Saribas O, Dalkara T. Chronic daily administration of selegiline and EGb 761 increases brain's resistance to ischemia in mice. Brain Res. 2001 Nov 02; 917(2):174-81. PMID: 11640903.
    View in: PubMed
  79. Ma J, Qiu J, Hirt L, Dalkara T, Moskowitz MA. Synergistic protective effect of caspase inhibitors and bFGF against brain injury induced by transient focal ischaemia. Br J Pharmacol. 2001 Jun; 133(3):345-50. PMID: 11375250; PMCID: PMC1572791.
  80. Elibol B, Söylemezoglu F, Unal I, Fujii M, Hirt L, Huang PL, Moskowitz MA, Dalkara T. Nitric oxide is involved in ischemia-induced apoptosis in brain: a study in neuronal nitric oxide synthase null mice. Neuroscience. 2001; 105(1):79-86. PMID: 11483302.
    View in: PubMed
  81. Ozen S, Usta Y, Sahin-Erdemli I, Orhan D, Gumusel B, Yang B, Gursoy Y, Tulunay O, Dalkara T, Bakkaloglu A, El-Nahas M. Association of nitric oxide production and apoptosis in a model of experimental nephropathy. Nephrol Dial Transplant. 2001 Jan; 16(1):32-8. PMID: 11208990.
    View in: PubMed
  82. Ikinci G, Capan Y, Senel S, Alaaddinoglu E, Dalkara T, Hincal AA. In vitro/in vivo studies on a buccal bioadhesive tablet formulation of carbamazepine. Pharmazie. 2000 Oct; 55(10):762-5. PMID: 11082839.
    View in: PubMed
  83. Bolay H, Gürsoy-Ozdemir Y, Unal I, Dalkara T. Altered mechanisms of motor-evoked potential generation after transient focal cerebral ischemia in the rat: implications for transcranial magnetic stimulation. Brain Res. 2000 Aug 04; 873(1):26-33. PMID: 10915807.
    View in: PubMed
  84. Gürsoy-Ozdemir Y, Bolay H, Saribas O, Dalkara T. Role of endothelial nitric oxide generation and peroxynitrite formation in reperfusion injury after focal cerebral ischemia. Stroke. 2000 Aug; 31(8):1974-80; discussion 1981. PMID: 10926966.
    View in: PubMed
  85. Yamada M, Huang Z, Dalkara T, Endres M, Laufs U, Waeber C, Huang PL, Liao JK, Moskowitz MA. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J Cereb Blood Flow Metab. 2000 Apr; 20(4):709-17. PMID: 10779015.
    View in: PubMed
  86. Anlar B, Söylemezoglu F, Elibol B, Dalkara T, Aysun S, Köse G, Belen D, Yalaz K. Apoptosis in brain biopsies of subacute sclerosing panencephalitis patients. Neuropediatrics. 1999 Oct; 30(5):239-42. PMID: 10598834.
    View in: PubMed
  87. Kilic E, Ozdemir YG, Bolay H, Kelestimur H, Dalkara T. Pinealectomy aggravates and melatonin administration attenuates brain damage in focal ischemia. J Cereb Blood Flow Metab. 1999 May; 19(5):511-6. PMID: 10326718.
    View in: PubMed
  88. Saka E, Elibol B, Erdem S, Dalkara T. Compartmental changes in expression of c-Fos and FosB proteins in intact and dopamine-depleted striatum after chronic apomorphine treatment. Brain Res. 1999 Apr 17; 825(1-2):104-14. PMID: 10216178.
    View in: PubMed
  89. Ozdemir YG, Bolay H, Erdem E, Dalkara T. Occlusion of the MCA by an intraluminal filament may cause disturbances in the hippocampal blood flow due to anomalies of circle of Willis and filament thickness. Brain Res. 1999 Mar 20; 822(1-2):260-4. PMID: 10082907.
    View in: PubMed
  90. Ikinci G, Capan Y, Senel S, Dalkara T, Hincal AA. Formulation and in vitro/in vivo investigation of carbamazepine controlled-release matrix tablets. Pharmazie. 1999 Feb; 54(2):139-41. PMID: 10084159.
    View in: PubMed
  91. Fink K, Zhu J, Namura S, Shimizu-Sasamata M, Endres M, Ma J, Dalkara T, Yuan J, Moskowitz MA. Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activation. J Cereb Blood Flow Metab. 1998 Oct; 18(10):1071-6. PMID: 9778183.
    View in: PubMed
  92. Bolay H, Dalkara T. Mechanisms of motor dysfunction after transient MCA occlusion: persistent transmission failure in cortical synapses is a major determinant. Stroke. 1998 Sep; 29(9):1988-93; discussion 1994. PMID: 9731628.
    View in: PubMed
  93. Dalkara T, Endres M, Moskowitz MA. Mechanisms of NO neurotoxicity. Prog Brain Res. 1998; 118:231-9. PMID: 9932445.
    View in: PubMed
  94. Demirci M, Ayata C, Dalkara T, Erdemli G, Onur R. Monitoring cellular edema at single-neuron level by electrical resistance measurements. J Neurosci Methods. 1997 Apr 04; 72(2):175-81. PMID: 9133582.
    View in: PubMed
  95. Dalkara T, Moskowitz MA. Neurotoxic and neuroprotective roles of nitric oxide in cerebral ischaemia. Int Rev Neurobiol. 1997; 40:319-36. PMID: 8989627.
    View in: PubMed
  96. Panahian N, Yoshida T, Huang PL, Hedley-Whyte ET, Dalkara T, Fishman MC, Moskowitz MA. Attenuated hippocampal damage after global cerebral ischemia in mice mutant in neuronal nitric oxide synthase. Neuroscience. 1996 May; 72(2):343-54. PMID: 8737405.
    View in: PubMed
  97. Moskowitz MA, Dalkara T. Nitric oxide and cerebral ischemia. Adv Neurol. 1996; 71:365-7; discussion 367-9. PMID: 8790812.
    View in: PubMed
  98. Dalkara T, Ayata C, Demirci M, Erdemli G, Onur R. Effects of cerebral ischemia on N-methyl-D-aspartate and dihydropyridine-sensitive calcium currents. An electrophysiological study in the rat hippocampus in situ. Stroke. 1996 Jan; 27(1):127-33. PMID: 8553388.
    View in: PubMed
  99. Irikura K, Huang PL, Ma J, Lee WS, Dalkara T, Fishman MC, Dawson TM, Snyder SH, Moskowitz MA. Cerebrovascular alterations in mice lacking neuronal nitric oxide synthase gene expression. Proc Natl Acad Sci U S A. 1995 Jul 18; 92(15):6823-7. PMID: 7542777; PMCID: PMC41421.
  100. Dalkara T, Irikura K, Huang Z, Panahian N, Moskowitz MA. Cerebrovascular responses under controlled and monitored physiological conditions in the anesthetized mouse. J Cereb Blood Flow Metab. 1995 Jul; 15(4):631-8. PMID: 7790412.
    View in: PubMed
  101. Dalkara T, Yoshida T, Irikura K, Moskowitz MA. Dual role of nitric oxide in focal cerebral ischemia. Neuropharmacology. 1994 Nov; 33(11):1447-52. PMID: 7532828.
    View in: PubMed
  102. Huang Z, Huang PL, Panahian N, Dalkara T, Fishman MC, Moskowitz MA. Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science. 1994 Sep 23; 265(5180):1883-5. PMID: 7522345.
    View in: PubMed
  103. Dalkara T, Morikawa E, Panahian N, Moskowitz MA. Blood flow-dependent functional recovery in a rat model of focal cerebral ischemia. Am J Physiol. 1994 Aug; 267(2 Pt 2):H678-83. PMID: 8067423.
    View in: PubMed
  104. Morikawa E, Moskowitz MA, Huang Z, Yoshida T, Irikura K, Dalkara T. L-arginine infusion promotes nitric oxide-dependent vasodilation, increases regional cerebral blood flow, and reduces infarction volume in the rat. Stroke. 1994 Feb; 25(2):429-35. PMID: 7508154.
    View in: PubMed
  105. Anlar S, Capan Y, Güven O, Gögüs A, Dalkara T, Hincal AA. Formulation and in vitro-in vivo evaluation of buccoadhesive morphine sulfate tablets. Pharm Res. 1994 Feb; 11(2):231-6. PMID: 8165181.
    View in: PubMed
  106. Dalkara T, Moskowitz MA. The complex role of nitric oxide in the pathophysiology of focal cerebral ischemia. Brain Pathol. 1994 Jan; 4(1):49-57. PMID: 7517769.
    View in: PubMed
  107. Sungur A, Ruacan S, Gungen Y, Dalkara T. Myasthenia gravis and primary squamous cell carcinoma of the thymus. Arch Pathol Lab Med. 1993 Sep; 117(9):937-8. PMID: 8368909.
    View in: PubMed
  108. Topaktas S, Dener S, Kenis M, Dalkara T. Myasthenia gravis and vitiligo. Muscle Nerve. 1993 May; 16(5):566-7. PMID: 8515767.
    View in: PubMed
  109. Topaktas S, Dalkara T, Onur R, Ruacan S. Intrathymic injection of D-penicillamine does not induce myasthenia-like disorder in the mouse and rat. Muscle Nerve. 1992 Nov; 15(11):1299-300. PMID: 1488069.
    View in: PubMed
  110. Dalkara T, Erdemli G, Barun S, Onur R. Glycine is required for NMDA receptor activation: electrophysiological evidence from intact rat hippocampus. Brain Res. 1992 Apr 03; 576(2):197-202. PMID: 1387577.
    View in: PubMed
  111. Senel S, Capan Y, Dalkara T, Inanç N, Hincal AA. Formulation, bioavailability, and pharmacokinetics of sustained-release potassium chloride tablets. Pharm Res. 1991 Oct; 8(10):1313-7. PMID: 1796051.
    View in: PubMed
  112. Oztekin NS, Saygi SS, Dalkara T, Senses I, Zileli T. High dose anticholinergic therapy (biperiden) in dystonia. Clin Neurol Neurosurg. 1991; 93(1):35-7. PMID: 1651189.
    View in: PubMed
  113. Dalkara T, Tan E, Erdemli G, Onur R, Zileli T. Electrophysiological evidence for activation of NMDA receptors and its antagonism by MK-801 in cerebral ischemia. Brain Res. 1990 Nov 05; 532(1-2):101-6. PMID: 1980849.
    View in: PubMed
  114. Dalkara T, Onur R, Subutay N, Unol B, Kücükali T, Erbengi T, Zileli T. Acute idiopathic demyelinating polyneuropathy: passive transfer to mice by immunoglobulin. Neuroreport. 1990 Oct; 1(2):145-8. PMID: 2129869.
    View in: PubMed
  115. Erdemli G, Dalkara T, Onur R. Glutamate and glycine induce a negative wave on hippocampal field response through NMDA receptors. Brain Res. 1990 Apr 30; 514(2):293-9. PMID: 1972639.
    View in: PubMed
  116. Dalkara T, Sofuoglu M, Onur R. Glutamate, without GABA antagonists, induces synchronized discharges in intact hippocampus via NMDA receptors. Brain Res. 1989 Sep 25; 498(1):123-30. PMID: 2571393.
    View in: PubMed
  117. Dalkara T, Namer IJ, Onur R, Zileli T. Intravenously and iontophoretically administered naloxone reverses ischemic changes in rat hippocampus. Stroke. 1989 Aug; 20(8):1059-64. PMID: 2547254.
    View in: PubMed
  118. Topaktas S, Onur R, Dalkara T. Calcium channel blockers and essential tremor. Eur Neurol. 1987; 27(2):114-9. PMID: 3622581.
    View in: PubMed
  119. Dalkara T, Onur R. Facilitatory effects of dexamethasone on neuromuscular transmission. Exp Neurol. 1987 Jan; 95(1):116-25. PMID: 3025008.
    View in: PubMed
  120. Dalkara T, Saederup E, Squires RF, Krnjevic K. Iontophoretic studies on rat hippocampus with some novel GABA antagonists. Life Sci. 1986 Aug 04; 39(5):415-22. PMID: 2874465.
    View in: PubMed
  121. Yim CC, Krnjevic K, Dalkara T. Ephaptically generated potentials in CA1 neurons of rat's hippocampus in situ. J Neurophysiol. 1986 Jul; 56(1):99-122. PMID: 3746402.
    View in: PubMed
  122. Dalkara T. Nipecotic acid, an uptake blocker, prevents fading of the gamma-aminobutyric acid effect. Brain Res. 1986 Feb 26; 366(1-2):314-9. PMID: 3008910.
    View in: PubMed
  123. Dalkara T, Krnjevic K, Ropert N, Yim CY. Chemical modulation of ephaptic activation of CA3 hippocampal pyramids. Neuroscience. 1986 Feb; 17(2):361-70. PMID: 2871519.
    View in: PubMed
  124. Krnjevic K, Dalkara T, Yim C. Synchronization of pyramidal cell firing by ephaptic currents in hippocampus in situ. Adv Exp Med Biol. 1986; 203:413-23. PMID: 3788710.
    View in: PubMed
  125. Dalkara T, Onur R, Ruacan SA, Topaktas S. The effects of myasthenic immunoglobulins on neuromuscular transmission and thymus histology in mice. Neurology. 1983 Oct; 33(10):1356-9. PMID: 6310440.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Dalkara's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (578)
Explore
_
Co-Authors (16)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Physical Neighbors
_