Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Navid Madani, Ph.D.


Knowledge and Attitude of Iranian Dental Students towards HIV/AIDS in Tehran Universities
International, 06/19/06 - 08/15/06

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AI134494 (MADANI, NAVID) Jul 14, 2017 - Jun 30, 2022
    Prevention of HIV-1 transmission by small-molecule CD4-mimetic entry inhibitors
    Role: Principal Investigator
  2. R56AI090682 (MADANI, NAVID) Sep 3, 2010 - May 31, 2012
    Design of dendrimeric HIV-1 transmission inhibitors targeting gp120 Phe-43 cavity
    Role: Principal Investigator
  3. F32NS043260 (MADANI, NAVID) Aug 1, 2001
    Biophysical characterization of chemokine receptors
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Madani N. Be the voice for scientists in Iran. Science. 2022 11 11; 378(6620):578. PMID: 36356158.
    Citations:    Fields:    
  2. Anang S, Richard J, Bourassa C, Goyette G, Chiu TJ, Chen HC, Smith AB, Madani N, Finzi A, Sodroski J. Characterization of Human Immunodeficiency Virus (HIV-1) Envelope Glycoprotein Variants Selected for Resistance to a CD4-Mimetic Compound. J Virol. 2022 09 14; 96(17):e0063622. PMID: 35980207; PMCID: PMC9472635.
    Citations:    Fields:    
  3. Fritschi CJ, Liang S, Mohammadi M, Anang S, Moraca F, Chen J, Madani N, Sodroski JG, Abrams CF, Hendrickson WA, Smith AB. Identification of gp120 Residue His105 as a Novel Target for HIV-1 Neutralization by Small-Molecule CD4-Mimics. ACS Med Chem Lett. 2021 Nov 11; 12(11):1824-1831. PMID: 34795873; PMCID: PMC8591726.
  4. Aghila Rani KG, Hamad MA, Zaher DM, Sieburth SM, Madani N, Al-Tel TH. Drug development post COVID-19 pandemic: toward a better system to meet current and future global health challenges. Expert Opin Drug Discov. 2021 04; 16(4):365-371. PMID: 33356641.
    Citations: 3     Fields:    Translation:HumansCells
  5. Prévost J, Tolbert WD, Medjahed H, Sherburn RT, Madani N, Zoubchenok D, Gendron-Lepage G, Gaffney AE, Grenier MC, Kirk S, Vergara N, Han C, Mann BT, Chénine AL, Ahmed A, Chaiken I, Kirchhoff F, Hahn BH, Haim H, Abrams CF, Smith AB, Sodroski J, Pazgier M, Finzi A. The HIV-1 Env gp120 Inner Domain Shapes the Phe43 Cavity and the CD4 Binding Site. mBio. 2020 05 26; 11(3). PMID: 32457241.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  6. Karamouzian M, Madani N. COVID-19 response in the Middle East and north Africa: challenges and paths forward. Lancet Glob Health. 2020 07; 8(7):e886-e887. PMID: 32416767.
    Citations: 16     Fields:    Translation:HumansPHPublic Health
  7. Joshi VR, Newman RM, Pack ML, Power KA, Munro JB, Okawa K, Madani N, Sodroski JG, Schmidt AG, Allen TM. Gp41-targeted antibodies restore infectivity of a fusion-deficient HIV-1 envelope glycoprotein. PLoS Pathog. 2020 05; 16(5):e1008577. PMID: 32392227; PMCID: PMC7241850.
    Citations:    Fields:    Translation:HumansCells
  8. Zou S, Zhang S, Gaffney A, Ding H, Lu M, Grover JR, Farrell M, Nguyen HT, Zhao C, Anang S, Zhao M, Mohammadi M, Blanchard SC, Abrams C, Madani N, Mothes W, Kappes JC, Smith AB, Sodroski J. Long-Acting BMS-378806 Analogues Stabilize the State-1 Conformation of the Human Immunodeficiency Virus Type 1 Envelope Glycoproteins. J Virol. 2020 05 04; 94(10). PMID: 32161177.
    Citations: 14     Fields:    Translation:HumansCells
  9. Zhao C, Princiotto AM, Nguyen HT, Zou S, Zhao ML, Zhang S, Herschhorn A, Farrell M, Pahil K, Melillo B, Sambasivarao SV, Abrams C, Smith AB, Madani N, Sodroski J. Strain-Dependent Activation and Inhibition of Human Immunodeficiency Virus Entry by a Specific PF-68742 Stereoisomer. J Virol. 2019 11 01; 93(21). PMID: 31391272; PMCID: PMC6803283.
    Citations:    Fields:    Translation:HumansCells
  10. Alipour Darvishi Z, Doroudi F, Madani N. Fuzzy Modeling of the Enactment of Stigma by Healthcare Personnel Toward People Living with HIV in the Frame of Counterfactual Thinking: A Mixed-Method Approach. AIDS Res Hum Retroviruses. 2018 09; 34(9):808-815. PMID: 30129774.
    Citations:    Fields:    Translation:Humans
  11. Princiotto AM, Vrbanac VD, Melillo B, Park J, Tager AM, Smith AB, Sodroski J, Madani N. A Small-Molecule CD4-Mimetic Compound Protects Bone Marrow-Liver-Thymus Humanized Mice From HIV-1 Infection. J Infect Dis. 2018 07 02; 218(3):471-475. PMID: 29617845; PMCID: PMC6049021.
    Citations: 11     Fields:    Translation:AnimalsCells
  12. Madani N, Princiotto AM, Mach L, Ding S, Prevost J, Richard J, Hora B, Sutherland L, Zhao CA, Conn BP, Bradley T, Moody MA, Melillo B, Finzi A, Haynes BF, Smith Iii AB, Santra S, Sodroski J. A CD4-mimetic compound enhances vaccine efficacy against stringent immunodeficiency virus challenge. Nat Commun. 2018 06 18; 9(1):2363. PMID: 29915222.
    Citations: 20     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  13. Castillo-Menendez LR, Witt K, Espy N, Princiotto A, Madani N, Pacheco B, Finzi A, Sodroski J. Comparison of Uncleaved and Mature Human Immunodeficiency Virus Membrane Envelope Glycoprotein Trimers. J Virol. 2018 06 15; 92(12). PMID: 29618643; PMCID: PMC5974486.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  14. Madani N. Gender equality is crucial to the fight for better HIV treatment access and outcomes in the MENA region. J Int AIDS Soc. 2018 03; 21(3). PMID: 29504249; PMCID: PMC5835842.
    Citations:    Fields:    Translation:Humans
  15. Karamouzian M, Madani N, Doroudi F, Haghdoost AA. Tackling HIV in MENA: Talk Is Not Enough-It Is Time for Bold Actions: A Response to Recent Commentaries. Int J Health Policy Manag. 2018 02 01; 7(2):199-200. PMID: 29524947; PMCID: PMC5819383.
    Citations:    Fields:    Translation:Humans
  16. Pancera M, Lai YT, Bylund T, Druz A, Narpala S, O'Dell S, Schön A, Bailer RT, Chuang GY, Geng H, Louder MK, Rawi R, Soumana DI, Finzi A, Herschhorn A, Madani N, Sodroski J, Freire E, Langley DR, Mascola JR, McDermott AB, Kwong PD. Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529. Nat Chem Biol. 2017 Oct; 13(10):1115-1122. PMID: 28825711; PMCID: PMC5676566.
    Citations: 57     Fields:    
  17. Johnson J, Zhai Y, Salimi H, Espy N, Eichelberger N, DeLeon O, O'Malley Y, Courter J, Smith AB, Madani N, Sodroski J, Haim H. Induction of a Tier-1-Like Phenotype in Diverse Tier-2 Isolates by Agents That Guide HIV-1 Env to Perturbation-Sensitive, Nonnative States. J Virol. 2017 08 01; 91(15). PMID: 28490588; PMCID: PMC5512248.
    Citations: 6     Fields:    Translation:HumansCells
  18. Nguyen HT, Madani N, Ding H, Elder E, Princiotto A, Gu C, Darby P, Alin J, Herschhorn A, Kappes JC, Mao Y, Sodroski JG. Evaluation of the contribution of the transmembrane region to the ectodomain conformation of the human immunodeficiency virus (HIV-1) envelope glycoprotein. Virol J. 2017 02 16; 14(1):33. PMID: 28209172; PMCID: PMC5314615.
    Citations: 8     Fields:    Translation:HumansCells
  19. Pacheco B, Alsahafi N, Debbeche O, Prévost J, Ding S, Chapleau JP, Herschhorn A, Madani N, Princiotto A, Melillo B, Gu C, Zeng X, Mao Y, Smith AB, Sodroski J, Finzi A. Residues in the gp41 Ectodomain Regulate HIV-1 Envelope Glycoprotein Conformational Transitions Induced by gp120-Directed Inhibitors. J Virol. 2017 03 01; 91(5). PMID: 28003492; PMCID: PMC5309946.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  20. Karamouzian M, Madani N, Doroudi F, Haghdoost AA. Improving the Quality and Quantity of HIV Data in the Middle East and North Africa: Key Challenges and Ways Forward. Int J Health Policy Manag. 2017 02 01; 6(2):65-69. PMID: 28812781; PMCID: PMC5287931.
    Citations: 14     Fields:    Translation:Humans
  21. Madani N, Princiotto AM, Zhao C, Jahanbakhshsefidi F, Mertens M, Herschhorn A, Melillo B, Smith AB, Sodroski J. Activation and Inactivation of Primary Human Immunodeficiency Virus Envelope Glycoprotein Trimers by CD4-Mimetic Compounds. J Virol. 2017 Feb 01; 91(3). PMID: 27881646; PMCID: PMC5244334.
    Citations: 27     Fields:    Translation:HumansCells
  22. Ding S, Verly MM, Princiotto A, Melillo B, Moody AM, Bradley T, Easterhoff D, Roger M, Hahn BH, Madani N, Smith AB, Haynes BF, Sodroski J, Finzi A. Short Communication: Small-Molecule CD4 Mimetics Sensitize HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity by Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Nonhuman Primates. AIDS Res Hum Retroviruses. 2017 05; 33(5):428-431. PMID: 27846736; PMCID: PMC5439425.
    Citations: 13     Fields:    Translation:AnimalsCells
  23. Ahani R, Roohvand F, Cohan RA, Etemadzadeh MH, Mohajel N, Behdani M, Shahosseini Z, Madani N, Azadmanesh K. Sindbis Virus-Pseudotyped Lentiviral Vectors Carrying VEGFR2-Specific Nanobody for Potential Transductional Targeting of Tumor Vasculature. Mol Biotechnol. 2016 Nov; 58(11):738-747. PMID: 27647452.
    Citations: 9     Fields:    Translation:HumansCells
  24. Bradley T, Trama A, Tumba N, Gray E, Lu X, Madani N, Jahanbakhsh F, Eaton A, Xia SM, Parks R, Lloyd KE, Sutherland LL, Scearce RM, Bowman CM, Barnett S, Abdool-Karim SS, Boyd SD, Melillo B, Smith AB, Sodroski J, Kepler TB, Alam SM, Gao F, Bonsignori M, Liao HX, Moody MA, Montefiori D, Santra S, Morris L, Haynes BF. Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity. EBioMedicine. 2016 Oct; 12:196-207. PMID: 27612593.
    Citations: 22     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  25. Madani N, Princiotto AM, Easterhoff D, Bradley T, Luo K, Williams WB, Liao HX, Moody MA, Phad GE, Vázquez Bernat N, Melillo B, Santra S, Smith AB, Karlsson Hedestam GB, Haynes B, Sodroski J. Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Primates Neutralize Primary Human Immunodeficiency Viruses (HIV-1) Sensitized by CD4-Mimetic Compounds. J Virol. 2016 05 15; 90(10):5031-5046. PMID: 26962221; PMCID: PMC4859707.
    Citations: 24     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  26. Gökengin D, Madani N. Response to letter to the editor re 'HIV Trends: Defining "The Middle East'. Int J Infect Dis. 2016 07; 48:124. PMID: 27109106.
    Citations:    Fields:    Translation:Humans
  27. Gökengin D, Doroudi F, Tohme J, Collins B, Madani N. HIV/AIDS: trends in the Middle East and North Africa region. Int J Infect Dis. 2016 Mar; 44:66-73. PMID: 26948920.
    Citations: 49     Fields:    Translation:HumansPHPublic Health
  28. Himmich H, Madani N. The state of harm reduction in the Middle East and North Africa: A focus on Iran and Morocco. Int J Drug Policy. 2016 05; 31:184-9. PMID: 27012581.
    Citations: 11     Fields:    Translation:Humans
  29. Melillo B, Liang S, Park J, Schön A, Courter JR, LaLonde JM, Wendler DJ, Princiotto AM, Seaman MS, Freire E, Sodroski J, Madani N, Hendrickson WA, Smith AB. Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition. ACS Med Chem Lett. 2016 Mar 10; 7(3):330-4. PMID: 26985324; PMCID: PMC4789667.
    Citations: 43     
  30. Madani N. Visa rules imperil collaboration. Science. 2016 Jan 15; 351(6270):234. PMID: 26816368.
    Citations:    Fields:    
  31. Richard J, Veillette M, Brassard N, Iyer SS, Roger M, Martin L, Pazgier M, Schön A, Freire E, Routy JP, Smith AB, Park J, Jones DM, Courter JR, Melillo BN, Kaufmann DE, Hahn BH, Permar SR, Haynes BF, Madani N, Sodroski JG, Finzi A. CD4 mimetics sensitize HIV-1-infected cells to ADCC. Proc Natl Acad Sci U S A. 2015 May 19; 112(20):E2687-94. PMID: 25941367; PMCID: PMC4443331.
    Citations: 82     Fields:    Translation:HumansCells
  32. Tuyishime M, Danish M, Princiotto A, Mankowski MK, Lawrence R, Lombart HG, Esikov K, Berniac J, Liang K, Ji J, Ptak RG, Madani N, Cocklin S. Discovery and optimization of novel small-molecule HIV-1 entry inhibitors using field-based virtual screening and bioisosteric replacement. Bioorg Med Chem Lett. 2014 Dec 01; 24(23):5439-45. PMID: 25454268; PMCID: PMC4355043.
    Citations: 12     Fields:    Translation:HumansCells
  33. Pancera M, Druz A, Zhou T, O'Dell S, Louder M, Madani N, Herschhorn A, Sodroski J, Mascola JR, Kwong PD. Structure of BMS-806, a Small-molecule HIV-1 Entry Inhibitor, Bound to BG505 SOSIP.664 HIV-1 Env Trimer. AIDS Res Hum Retroviruses. 2014 Oct; 30 Suppl 1:A151. PMID: 25357424.
  34. Madani N, Princiotto AM, Schön A, LaLonde J, Feng Y, Freire E, Park J, Courter JR, Jones DM, Robinson J, Liao HX, Moody MA, Permar S, Haynes B, Smith AB, Wyatt R, Sodroski J. CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies. J Virol. 2014 Jun; 88(12):6542-55. PMID: 24696475.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  35. Chahil-Graf R, Madani N. Women, culture and the HIV epidemic in MENA. J Int AIDS Soc. 2014; 17:19074. PMID: 24629846; PMCID: PMC3955763.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  36. Courter JR, Madani N, Sodroski J, Schön A, Freire E, Kwong PD, Hendrickson WA, Chaiken IM, LaLonde JM, Smith AB. Structure-based design, synthesis and validation of CD4-mimetic small molecule inhibitors of HIV-1 entry: conversion of a viral entry agonist to an antagonist. Acc Chem Res. 2014 Apr 15; 47(4):1228-37. PMID: 24502450.
    Citations: 36     Fields:    Translation:HumansCells
  37. Lalonde JM, Le-Khac M, Jones DM, Courter JR, Park J, Schön A, Princiotto AM, Wu X, Mascola JR, Freire E, Sodroski J, Madani N, Hendrickson WA, Smith AB. Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-Ray and Thermodynamic Characterization. ACS Med Chem Lett. 2013 Mar 14; 4(3):338-343. PMID: 23667716.
    Citations: 32     
  38. Modjarrad K, Mohraz M, Madani N. AIDS epidemic: Iran needs global support to fight HIV. Nature. 2013 Feb 21; 494(7437):314. PMID: 23426315.
    Citations:    Fields:    Translation:HumansPHPublic Health
  39. Tuzer F, Madani N, Kamanna K, Zentner I, LaLonde J, Holmes A, Upton E, Rajagopal S, McFadden K, Contarino M, Sodroski J, Chaiken I. HIV-1 Env gp120 structural determinants for peptide triazole dual receptor site antagonism. Proteins. 2013 Feb; 81(2):271-90. PMID: 23011758.
    Citations: 14     Fields:    Translation:HumansCells
  40. Choi WT, Kumar S, Madani N, Han X, Tian S, Dong CZ, Liu D, Duggineni S, Yuan J, Sodroski JG, Huang Z, An J. A novel synthetic bivalent ligand to probe chemokine receptor CXCR4 dimerization and inhibit HIV-1 entry. Biochemistry. 2012 Sep 11; 51(36):7078-86. PMID: 22897429.
    Citations: 16     Fields:    Translation:Cells
  41. Kortagere S, Madani N, Mankowski MK, Schön A, Zentner I, Swaminathan G, Princiotto A, Anthony K, Oza A, Sierra LJ, Passic SR, Wang X, Jones DM, Stavale E, Krebs FC, Martín-García J, Freire E, Ptak RG, Sodroski J, Cocklin S, Smith AB. Inhibiting early-stage events in HIV-1 replication by small-molecule targeting of the HIV-1 capsid. J Virol. 2012 Aug; 86(16):8472-81. PMID: 22647699.
    Citations: 44     Fields:    Translation:HumansCells
  42. LaLonde JM, Kwon YD, Jones DM, Sun AW, Courter JR, Soeta T, Kobayashi T, Princiotto AM, Wu X, Schön A, Freire E, Kwong PD, Mascola JR, Sodroski J, Madani N, Smith AB. Structure-based design, synthesis, and characterization of dual hotspot small-molecule HIV-1 entry inhibitors. J Med Chem. 2012 May 10; 55(9):4382-96. PMID: 22497421.
    Citations: 51     Fields:    Translation:HumansCells
  43. Dong CZ, Tian S, Madani N, Choi WT, Kumar S, Liu D, Sodroski JG, Huang Z, An J. Role of CXCR4 internalization in the anti-HIV activity of stromal cell-derived factor-1a probed by a novel synthetically and modularly modified-chemokine analog. Exp Biol Med (Maywood). 2011 Dec; 236(12):1413-9. PMID: 22101518.
    Citations: 7     Fields:    Translation:HumansCells
  44. Malavia NK, Zurakowski D, Schroeder A, Princiotto AM, Laury AR, Barash HE, Sodroski J, Langer R, Madani N, Kohane DS. Liposomes for HIV prophylaxis. Biomaterials. 2011 Nov; 32(33):8663-8. PMID: 21862123.
    Citations: 10     Fields:    Translation:HumansAnimals
  45. Haim H, Strack B, Kassa A, Madani N, Wang L, Courter JR, Princiotto A, McGee K, Pacheco B, Seaman MS, Smith AB, Sodroski J. Contribution of intrinsic reactivity of the HIV-1 envelope glycoproteins to CD4-independent infection and global inhibitor sensitivity. PLoS Pathog. 2011 Jun; 7(6):e1002101. PMID: 21731494.
    Citations: 83     Fields:    Translation:HumansCells
  46. Schön A, Madani N, Smith AB, Lalonde JM, Freire E. Some binding-related drug properties are dependent on thermodynamic signature. Chem Biol Drug Des. 2011 Mar; 77(3):161-5. PMID: 21288305.
    Citations: 15     Fields:    Translation:HumansCells
  47. Lalonde JM, Elban MA, Courter JR, Sugawara A, Soeta T, Madani N, Princiotto AM, Kwon YD, Kwong PD, Schön A, Freire E, Sodroski J, Smith AB. Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screening. Bioorg Med Chem. 2011 Jan 01; 19(1):91-101. PMID: 21169023.
    Citations: 34     Fields:    Translation:Cells
  48. Zhukovsky MA, Basmaciogullari S, Pacheco B, Wang L, Madani N, Haim H, Sodroski J. Thermal stability of the human immunodeficiency virus type 1 (HIV-1) receptors, CD4 and CXCR4, reconstituted in proteoliposomes. PLoS One. 2010 Oct 13; 5(10):e13249. PMID: 20967243.
    Citations: 3     Fields:    Translation:Cells
  49. Bird GH, Madani N, Perry AF, Princiotto AM, Supko JG, He X, Gavathiotis E, Sodroski JG, Walensky LD. Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic. Proc Natl Acad Sci U S A. 2010 Aug 10; 107(32):14093-8. PMID: 20660316.
    Citations: 108     Fields:    Translation:Humans
  50. Kassa A, Madani N, Schön A, Haim H, Finzi A, Xiang SH, Wang L, Princiotto A, Pancera M, Courter J, Smith AB, Freire E, Kwong PD, Sodroski J. Transitions to and from the CD4-bound conformation are modulated by a single-residue change in the human immunodeficiency virus type 1 gp120 inner domain. J Virol. 2009 Sep; 83(17):8364-78. PMID: 19535453.
    Citations: 37     Fields:    Translation:HumansCells
  51. Haim H, Si Z, Madani N, Wang L, Courter JR, Princiotto A, Kassa A, DeGrace M, McGee-Estrada K, Mefford M, Gabuzda D, Smith AB, Sodroski J. Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state. PLoS Pathog. 2009 Apr; 5(4):e1000360. PMID: 19343205.
    Citations: 111     Fields:    Translation:HumansAnimalsCells
  52. Madani N, Schön A, Princiotto AM, Lalonde JM, Courter JR, Soeta T, Ng D, Wang L, Brower ET, Xiang SH, Kwon YD, Huang CC, Wyatt R, Kwong PD, Freire E, Smith AB, Sodroski J. Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 gp120. Structure. 2008 Nov 12; 16(11):1689-701. PMID: 19000821.
    Citations: 93     Fields:    Translation:HumansCells
  53. Gopi H, Umashankara M, Pirrone V, LaLonde J, Madani N, Tuzer F, Baxter S, Zentner I, Cocklin S, Jawanda N, Miller SR, Schön A, Klein JC, Freire E, Krebs FC, Smith AB, Sodroski J, Chaiken I. Structural determinants for affinity enhancement of a dual antagonist peptide entry inhibitor of human immunodeficiency virus type-1. J Med Chem. 2008 May 08; 51(9):2638-47. PMID: 18402432.
    Citations: 25     Fields:    Translation:HumansCells
  54. Liu D, Madani N, Li Y, Cao R, Choi WT, Kawatkar SP, Lim MY, Kumar S, Dong CZ, Wang J, Russell JD, Lefebure CR, An J, Wilson S, Gao YG, Pallansch LA, Sodroski JG, Huang Z. Crystal structure and structural mechanism of a novel anti-human immunodeficiency virus and D-amino acid-containing chemokine. J Virol. 2007 Oct; 81(20):11489-98. PMID: 17686848; PMCID: PMC2045531.
    Citations: 11     Fields:    Translation:HumansCells
  55. Schön A, Madani N, Klein JC, Hubicki A, Ng D, Yang X, Smith AB, Sodroski J, Freire E. Thermodynamics of binding of a low-molecular-weight CD4 mimetic to HIV-1 gp120. Biochemistry. 2006 Sep 12; 45(36):10973-80. PMID: 16953583.
    Citations: 85     Fields:    Translation:HumansAnimalsCells
  56. Madani N, Hubicki AM, Perdigoto AL, Springer M, Sodroski J. Inhibition of human immunodeficiency virus envelope glycoprotein- mediated single cell lysis by low-molecular-weight antagonists of viral entry. J Virol. 2007 Jan; 81(2):532-8. PMID: 16943294; PMCID: PMC1797463.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  57. Kumar S, Choi WT, Dong CZ, Madani N, Tian S, Liu D, Wang Y, Pesavento J, Wang J, Fan X, Yuan J, Fritzsche WR, An J, Sodroski JG, Richman DD, Huang Z. SMM-chemokines: a class of unnatural synthetic molecules as chemical probes of chemokine receptor biology and leads for therapeutic development. Chem Biol. 2006 Jan; 13(1):69-79. PMID: 16426973.
    Citations: 17     Fields:    Translation:HumansCells
  58. Dong CZ, Kumar S, Choi WT, Madani N, Tian S, An J, Sodroski JG, Huang Z. Different stereochemical requirements for CXCR4 binding and signaling functions as revealed by an anti-HIV, D-amino acid-containing SMM-chemokine ligand. J Med Chem. 2005 Dec 15; 48(25):7923-4. PMID: 16335916.
    Citations: 8     Fields:    Translation:HumansCells
  59. Choi WT, Tian S, Dong CZ, Kumar S, Liu D, Madani N, An J, Sodroski JG, Huang Z. Unique ligand binding sites on CXCR4 probed by a chemical biology approach: implications for the design of selective human immunodeficiency virus type 1 inhibitors. J Virol. 2005 Dec; 79(24):15398-404. PMID: 16306611; PMCID: PMC1316031.
    Citations: 36     Fields:    Translation:HumansCells
  60. Xiang SH, Farzan M, Si Z, Madani N, Wang L, Rosenberg E, Robinson J, Sodroski J. Functional mimicry of a human immunodeficiency virus type 1 coreceptor by a neutralizing monoclonal antibody. J Virol. 2005 May; 79(10):6068-77. PMID: 15857992; PMCID: PMC1091675.
    Citations: 24     Fields:    Translation:HumansCells
  61. Madani N, Perdigoto AL, Srinivasan K, Cox JM, Chruma JJ, LaLonde J, Head M, Smith AB, Sodroski JG. Localized changes in the gp120 envelope glycoprotein confer resistance to human immunodeficiency virus entry inhibitors BMS-806 and #155. J Virol. 2004 Apr; 78(7):3742-52. PMID: 15016894; PMCID: PMC371073.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  62. Si Z, Madani N, Cox JM, Chruma JJ, Klein JC, Schön A, Phan N, Wang L, Biorn AC, Cocklin S, Chaiken I, Freire E, Smith AB, Sodroski JG. Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins. Proc Natl Acad Sci U S A. 2004 Apr 06; 101(14):5036-41. PMID: 15051887; PMCID: PMC387369.
    Citations: 139     Fields:    Translation:HumansCells
  63. Biorn AC, Cocklin S, Madani N, Si Z, Ivanovic T, Samanen J, Van Ryk DI, Pantophlet R, Burton DR, Freire E, Sodroski J, Chaiken IM. Mode of action for linear peptide inhibitors of HIV-1 gp120 interactions. Biochemistry. 2004 Feb 24; 43(7):1928-38. PMID: 14967033.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  64. LaBonte JA, Madani N, Sodroski J. Cytolysis by CCR5-using human immunodeficiency virus type 1 envelope glycoproteins is dependent on membrane fusion and can be inhibited by high levels of CD4 expression. J Virol. 2003 Jun; 77(12):6645-59. PMID: 12767984; PMCID: PMC156190.
    Citations: 14     Fields:    Translation:HumansCells
  65. Madani N, Millette R, Platt EJ, Marin M, Kozak SL, Bloch DB, Kabat D. Implication of the lymphocyte-specific nuclear body protein Sp140 in an innate response to human immunodeficiency virus type 1. J Virol. 2002 Nov; 76(21):11133-8. PMID: 12368356; PMCID: PMC136615.
    Citations: 23     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.