Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Irving Itzkan, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Pettinato G, Coughlan MF, Zhang X, Chen L, Khan U, Glyavina M, Sheil CJ, Upputuri PK, Zakharov YN, Vitkin E, D'Assoro AB, Fisher RA, Itzkan I, Zhang L, Qiu L, Perelman LT. Spectroscopic label-free microscopy of changes in live cell chromatin and biochemical composition in transplantable organoids. Sci Adv. 2021 08; 7(34). PMID: 34407934; PMCID: PMC8373132.
    Citations: 3     Fields:    Translation:HumansCells
  2. Qiu L, Zhang L, Horowitz GL, Turzhitsky V, Coughlan MF, Glyavina M, Khan U, Zakharov YN, Vitkin E, Itzkan I, Perelman LT. Rapid detection and identification of bacteria directly from whole blood with light scattering spectroscopy based biosensor. Sens Actuators B Chem. 2021 Nov 01; 346. PMID: 34483482; PMCID: PMC8415441.
  3. Coughlan MF, Sawhney MS, Pleskow DK, Sheil CJ, Qiu L, Perelman LT. Measuring Droplets Expelled During Endoscopy to Investigate COVID-19 Transmission Risk. Gastroenterology. 2021 11; 161(5):1702-1704.e3. PMID: 34280387; PMCID: PMC8284060.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  4. Pleskow DK, Zhang L, Turzhitsky V, Coughlan MF, Khan U, Zhang X, Sheil CJ, Glyavina M, Chen L, Shinagare S, Zakharov YN, Vitkin E, Itzkan I, Perelman LT, Qiu L. Coherent confocal light scattering spectroscopic microscopy evaluates cancer progression and aggressiveness in live cells and tissue. ACS Photonics. 2021 Jul 21; 8(7):2050-2059. PMID: 34485615; PMCID: PMC8411902.
    Citations: 1     
  5. Sheil CJ, Khan U, Zakharov YN, Coughlan MF, Pleskow DK, Sawhney MS, Berzin TM, Cohen JM, Glyavina M, Zhang L, Itzkan I, Perelman LT, Qiu L. Two-photon polymerization nanofabrication of ultracompact light scattering spectroscopic probe for detection of pre-cancer in pancreatic cyst. Opt Lasers Eng. 2021 Jul; 142. PMID: 34305200; PMCID: PMC8294208.
  6. Turzhitsky V, Zhang L, Horowitz GL, Vitkin E, Khan U, Zakharov Y, Qiu L, Itzkan I, Perelman LT. Picoanalysis of Drugs in Biofluids with Quantitative Label-Free Surface-Enhanced Raman Spectroscopy. Small. 2018 11; 14(47):e1802392. PMID: 30369072; PMCID: PMC6389872.
    Citations: 8     Fields:    
  7. Qiu L, Zhang L, Turzhitsky V, Khan U, Zakharov Y, Kantekure K, Vitkin E, Itzkan I, Pleskow DK, Sawhney M, Berzin TM, Goldsmith JD, Perelman LT. Multispectral Endoscopy with Light Gating for Early Cancer Detection. IEEE J Sel Top Quantum Electron. 2019 Jan-Feb; 25(1). PMID: 31244520; PMCID: PMC6594557.
    Citations: 1     
  8. Qiu L, Chuttani R, Pleskow DK, Turzhitsky V, Khan U, Zakharov YN, Zhang L, Berzin TM, Yee EU, Sawhney MS, Li Y, Vitkin E, Goldsmith JD, Itzkan I, Perelman LT. Multispectral light scattering endoscopic imaging of esophageal precancer. Light Sci Appl. 2018; 7:17174. PMID: 30839534; PMCID: PMC6060057.
    Citations: 8     
  9. Zhang L, Pleskow DK, Turzhitsky V, Yee EU, Berzin TM, Sawhney M, Shinagare S, Vitkin E, Zakharov Y, Khan U, Wang F, Goldsmith JD, Goldberg S, Chuttani R, Itzkan I, Qiu L, Perelman LT. Light scattering spectroscopy identifies the malignant potential of pancreatic cysts during endoscopy. Nat Biomed Eng. 2017; 1. PMID: 29057146.
    Citations: 17     Fields:    
  10. Beskorovaynyy AV, Kopitsyn DS, Novikov AA, Ziangirova M, Skorikova GS, Kotelev MS, Gushchin PA, Ivanov EV, Getmansky MD, Itzkan I, Muradov AV, Vinokurov VA, Perelman LT. Rapid optimization of metal nanoparticle surface modification with high-throughput gel electrophoresis. ACS Nano. 2014 Feb 25; 8(2):1449-56. PMID: 24392839.
    Citations: 1     Fields:    
  11. Turzhitsky V, Qiu L, Itzkan I, Novikov AA, Kotelev MS, Getmanskiy M, Vinokurov VA, Muradov AV, Perelman LT. Spectroscopy of scattered light for the characterization of micro and nanoscale objects in biology and medicine. Appl Spectrosc. 2014; 68(2):133-54. PMID: 24480270.
    Citations: 5     Fields:    
  12. Qiu L, Turzhitsky V, Chuttani R, Pleskow D, Goldsmith JD, Guo L, Vitkin E, Itzkan I, Hanlon EB, Perelman LT. Spectral Imaging with Scattered Light: From Early Cancer Detection to Cell Biology. IEEE J Sel Top Quantum Electron. 2012 May; 18(3):1073-1083. PMID: 23087592.
    Citations: 10     
  13. Vitkin E, Turzhitsky V, Qiu L, Guo L, Itzkan I, Hanlon EB, Perelman LT. Photon diffusion near the point-of-entry in anisotropically scattering turbid media. Nat Commun. 2011 Dec 13; 2:587. PMID: 22158442.
    Citations: 17     Fields:    Translation:HumansCells
  14. Qiu L, Larson TA, Vitkin E, Guo L, Hanlon EB, Itzkan I, Sokolov KV, Perelman LT. Gold nanorod light scattering labels for biomedical imaging. Biomed Opt Express. 2010 Jul 15; 1(1):135-142. PMID: 21258453.
    Citations: 3     
  15. Qiu L, Pleskow DK, Chuttani R, Vitkin E, Leyden J, Ozden N, Itani S, Guo L, Sacks A, Goldsmith JD, Modell MD, Hanlon EB, Itzkan I, Perelman LT. Multispectral scanning during endoscopy guides biopsy of dysplasia in Barrett's esophagus. Nat Med. 2010 May; 16(5):603-6, 1p following 606. PMID: 20383155.
    Citations: 64     Fields:    Translation:Humans
  16. Lim KH, Salahuddin S, Qiu L, Fang H, Vitkin E, Ghiran IC, Modell MD, Takoudes T, Itzkan I, Hanlon EB, Sachs BP, Perelman LT. Light-scattering spectroscopy differentiates fetal from adult nucleated red blood cells: may lead to noninvasive prenatal diagnosis. Opt Lett. 2009 May 01; 34(9):1483-5. PMID: 19412313.
    Citations: 1     Fields:    Translation:HumansCells
  17. Qiu L, Chuttani R, Zhang S, Feng J, Itani S, Fang H, Pleskow D, Sawhney MS, Salahuddin S, Modell MD, Vitkin E, Hanlon EB, Itzkan I, Perelman LT. Diagnostic imaging of esophageal epithelium with clinical endoscopic polarized scanning spectroscopy instrument. Annu Int Conf IEEE Eng Med Biol Soc. 2009; 2009:1997-2000. PMID: 19964032.
    Citations: 1     Fields:    Translation:HumansCells
  18. Itzkan I, Qiu L, Fang H, Zaman MM, Vitkin E, Ghiran IC, Salahuddin S, Modell M, Andersson C, Kimerer LM, Cipolloni PB, Lim KH, Freedman SD, Bigio I, Sachs BP, Hanlon EB, Perelman LT. Confocal light absorption and scattering spectroscopic microscopy monitors organelles in live cells with no exogenous labels. Proc Natl Acad Sci U S A. 2007 Oct 30; 104(44):17255-60. PMID: 17956980.
    Citations: 49     Fields:    Translation:HumansCells
  19. Fang H, Qiu L, Vitkin E, Zaman MM, Andersson C, Salahuddin S, Kimerer LM, Cipolloni PB, Modell MD, Turner BS, Keates SE, Bigio I, Itzkan I, Freedman SD, Bansil R, Hanlon EB, Perelman LT. Confocal light absorption and scattering spectroscopic microscopy. Appl Opt. 2007 Apr 01; 46(10):1760-9. PMID: 17356619.
    Citations: 17     Fields:    
  20. Gurjar RS, Backman V, Perelman LT, Georgakoudi I, Badizadegan K, Itzkan I, Dasari RR, Feld MS. Imaging human epithelial properties with polarized light-scattering spectroscopy. Nat Med. 2001 Nov; 7(11):1245-8. PMID: 11689891.
    Citations: 66     Fields:    Translation:HumansCells
  21. Wallace MB, Perelman LT, Backman V, Crawford JM, Fitzmaurice M, Seiler M, Badizadegan K, Shields SJ, Itzkan I, Dasari RR, Van Dam J, Feld MS. Endoscopic detection of dysplasia in patients with Barrett's esophagus using light-scattering spectroscopy. Gastroenterology. 2000 Sep; 119(3):677-82. PMID: 10982761.
    Citations: 56     Fields:    Translation:Humans
  22. Backman V, Wallace MB, Perelman LT, Arendt JT, Gurjar R, Müller MG, Zhang Q, Zonios G, Kline E, McGilligan JA, Shapshay S, Valdez T, Badizadegan K, Crawford JM, Fitzmaurice M, Kabani S, Levin HS, Seiler M, Dasari RR, Itzkan I, Van Dam J, Feld MS, McGillican T. Detection of preinvasive cancer cells. Nature. 2000 Jul 06; 406(6791):35-6. PMID: 10894529.
    Citations: 99     Fields:    Translation:HumansCells
  23. Dark ML, Perelman LT, Itzkan I, Schaffer JL, Field MS. Physical properties of hydrated tissue determined by surface interferometry of laser-induced thermoelastic deformation. Phys Med Biol. 2000 Feb; 45(2):529-39. PMID: 10701519.
    Citations: 4     Fields:    Translation:Humans
  24. Hanlon EB, Manoharan R, Koo TW, Shafer KE, Motz JT, Fitzmaurice M, Kramer JR, Itzkan I, Dasari RR, Feld MS. Prospects for in vivo Raman spectroscopy. Phys Med Biol. 2000 Feb; 45(2):R1-59. PMID: 10701500.
    Citations: 140     Fields:    Translation:HumansAnimals
  25. Kneipp K, Kneipp H, Itzkan I, Dasari RR, Feld MS. Ultrasensitive chemical analysis by Raman spectroscopy. Chem Rev. 1999 Oct 13; 99(10):2957-76. PMID: 11749507.
    Citations: 133     Fields:    
  26. Hanlon EB, Itzkan I, Dasari RR, Feld MS, Ferrante RJ, McKee AC, Lathi D, Kowall NW. Near-infrared fluorescence spectroscopy detects Alzheimer's disease in vitro. Photochem Photobiol. 1999 Aug; 70(2):236-42. PMID: 10461462.
    Citations: 4     Fields:    Translation:Humans
  27. Berger AJ, Koo TW, Itzkan I, Horowitz G, Feld MS. Multicomponent blood analysis by near-infrared Raman spectroscopy. Appl Opt. 1999 May 01; 38(13):2916-26. PMID: 18319874.
    Citations: 35     Fields:    
  28. Wang TD, Crawford JM, Feld MS, Wang Y, Itzkan I, Van Dam J. In vivo identification of colonic dysplasia using fluorescence endoscopic imaging. Gastrointest Endosc. 1999 Apr; 49(4 Pt 1):447-55. PMID: 10202057.
    Citations: 18     Fields:    Translation:Humans
  29. Koo TW, Berger AJ, Itzkan I, Horowitz G, Feld MS. Reagentless blood analysis by near-infrared Raman spectroscopy. Diabetes Technol Ther. 1999; 1(2):153-7. PMID: 11475287.
    Citations: 5     Fields:    Translation:Humans
  30. Wang TD, Janes GS, Wang Y, Itzkan I, Van Dam J, Feld MS. Mathematical model of fluorescence endoscopic image formation. Appl Opt. 1998 Dec 01; 37(34):8103-11. PMID: 18301704.
    Citations: 5     Fields:    
  31. Dhingra JK, Zhang X, McMillan K, Kabani S, Manoharan R, Itzkan I, Feld MS, Shapshay SM. Diagnosis of head and neck precancerous lesions in an animal model using fluorescence spectroscopy. Laryngoscope. 1998 Apr; 108(4 Pt 1):471-5. PMID: 9546254.
    Citations: 9     Fields:    Translation:Animals
  32. Berger AJ, Koo TW, Itzkan I, Feld MS. An enhanced algorithm for linear multivariate calibration. Anal Chem. 1998 Feb 01; 70(3):623-7. PMID: 9470489.
    Citations: 10     Fields:    
  33. Berger AJ, Itzkan I, Feld MS. Feasibility of measuring blood glucose concentration by near-infrared Raman spectroscopy. Spectrochim Acta A Mol Biomol Spectrosc. 1997 Feb; 53A(2):287-92. PMID: 9097902.
    Citations: 16     Fields:    Translation:Humans
  34. Ingrams DR, Dhingra JK, Roy K, Perrault DF, Bottrill ID, Kabani S, Rebeiz EE, Pankratov MM, Shapshay SM, Manoharan R, Itzkan I, Feld MS. Autofluorescence characteristics of oral mucosa. Head Neck. 1997 Jan; 19(1):27-32. PMID: 9030941.
    Citations: 13     Fields:    Translation:Humans
  35. Dhingra JK, Perrault DF, McMillan K, Rebeiz EE, Kabani S, Manoharan R, Itzkan I, Feld MS, Shapshay SM. Early diagnosis of upper aerodigestive tract cancer by autofluorescence. Arch Otolaryngol Head Neck Surg. 1996 Nov; 122(11):1181-6. PMID: 8906052.
    Citations: 14     Fields:    Translation:Humans
  36. Zângaro RA, Silveira L, Manoharan R, Zonios G, Itzkan I, Dasari RR, Van Dam J, Feld MS. Rapid multiexcitation fluorescence spectroscopy system for in vivo tissue diagnosis. Appl Opt. 1996 Sep 01; 35(25):5211-9. PMID: 21102960.
    Citations: 11     Fields:    
  37. Tanaka K, Pacheco MT, Brennan Iii JF, Itzkan I, Berger AJ, Dasari RR, Feld MS. Compound parabolic concentrator probe for efficient light collection in spectroscopy of biological tissue. Appl Opt. 1996 Feb 01; 35(4):758-63. PMID: 21069066.
    Citations: 8     Fields:    
  38. Wu J, Wang Y, Perelman L, Itzkan I, Dasari RR, Feld MS. Three-dimensional imaging of objects embedded in turbid media with fluorescence and Raman spectroscopy. Appl Opt. 1995 Jun 20; 34(18):3425-30. PMID: 21052155.
    Citations: 3     Fields:    
  39. Perelman LT, Wu J, Wang Y, Itzkan I, Dasari RR, Feld MS. Time-dependent photon migration using path integrals. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 1995 Jun; 51(6):6134-6141. PMID: 9963353.
    Citations: 2     Fields:    
  40. Itzkan I, Albagli D, Dark ML, Perelman LT, von Rosenberg C, Feld MS. The thermoelastic basis of short pulsed laser ablation of biological tissue. Proc Natl Acad Sci U S A. 1995 Mar 14; 92(6):1960-4. PMID: 7892208; PMCID: PMC42402.
    Citations: 5     Fields:    Translation:HumansAnimals
  41. Wu J, Wang Y, Perelman L, Itzkan I, Dasari RR, Feld MS. Time-resolved multichannel imaging of fluorescent objects embedded in turbid media. Opt Lett. 1995 Mar 01; 20(5):489-91. PMID: 19859230.
    Citations: 4     Fields:    
  42. Schaffer JL, Dark M, Itzkan I, Albagli D, Perelman L, von Rosenberg C, Feld MS. Mechanisms of meniscal tissue ablation by short pulse laser irradiation. Clin Orthop Relat Res. 1995 Jan; (310):30-6. PMID: 7641455.
    Citations: 2     Fields:    Translation:HumansAnimals
  43. Albagli D, Dark M, Perelman LT, von Rosenberg C, Itzkan I, Feld MS. Photomechanical basis of laser ablation of biological tissue. Opt Lett. 1994 Nov 01; 19(21):1684-6. PMID: 19855621.
    Citations: 2     Fields:    
  44. Albagli D, Dark M, von Rosenberg C, Perelman L, Itzkan I, Feld MS. Laser-induced thermoelastic deformation: a three-dimensional solution and its application to the ablation of biological tissue. Med Phys. 1994 Aug; 21(8):1323-31. PMID: 7799877.
    Citations: 6     Fields:    Translation:Animals
  45. Perelman LT, Wu J, Itzkan I, Feld MS. Photon migration in turbid media using path integrals. Phys Rev Lett. 1994 Feb 28; 72(9):1341-1344. PMID: 10056688.
    Citations: 1     Fields:    
  46. Albagli D, Banish B, Dark M, Janes GS, von Rosenberg C, Perelman L, Itzkan I, Feld MS. Interferometric surface monitoring of biological tissue to study inertially confined ablation. Lasers Surg Med. 1994; 14(4):374-85. PMID: 8078387.
    Citations: 5     Fields:    Translation:HumansAnimals
  47. Izatt JA, Albagli D, Britton M, Jubas JM, Itzkan I, Feld MS. Wavelength dependence of pulsed laser ablation of calcified tissue. Lasers Surg Med. 1991; 11(3):238-49. PMID: 1861563.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  48. Dagenais DM, Woodroffe JA, Itzkan I. Optical beam shaping of a high power laser for uniform target illumination. Appl Opt. 1985 Mar 01; 24(5):671. PMID: 18217006.
    Citations:    Fields:    
  49. Tang SV, Gilchrest BA, Noe JM, Arndt KA, Bourgelais DB, Itzkan I. In vivo spectrophotometric evaluation of normal, lesional, and laser-treated skin in patients with port-wine stains. J Invest Dermatol. 1983 May; 80(5):420-3. PMID: 6841999.
    Citations: 1     Fields:    Translation:Humans
  50. Arndt KA, Noe JM, Northam DB, Itzkan I. Laser therapy. Basic concepts and nomenclature. J Am Acad Dermatol. 1981 Dec; 5(6):649-54. PMID: 7320259.
    Citations: 4     Fields:    Translation:Humans
  51. Naor D, Flusberg A, Itzkan I. Infrared laser photography with silver-halide emulsion. Appl Opt. 1981 Jul 15; 20(14):2574-84. PMID: 20332993.
    Citations:    Fields:    
  52. Northam DB, Guerra MA, Mack ME, Itzkan I, Deradourian C. High repetition rate frequency-doubled Nd:YAG laser for airborne bathymetry. Appl Opt. 1981 Mar 15; 20(6):968-71. PMID: 20309242.
    Citations:    Fields:    
  53. Morton RG, Mack ME, Itzkan I. Efficient cavity dumped dye laser. Appl Opt. 1978 Oct 15; 17(20):3268-75. PMID: 20203960.
    Citations:    Fields:    
  54. Northam DB, Mack ME, Itzkan I. Unstable resonator mode control in a transverse flow dye laser. Appl Opt. 1978 Mar 15; 17(6):931-5. PMID: 20197902.
    Citations:    Fields:    
  55. Kung RT, Itzkan I. Absolute oil fluorescence conversion efficiency. Appl Opt. 1976 Feb 01; 15(2):409-15. PMID: 20164982.
    Citations:    Fields:    
  56. Myer JA, Itzkan I, Kierstead E. Dye lasers in the ultraviolet. Nature. 1970 Feb 07; 225(5232):544-5. PMID: 16056602.
    Citations: 1     Fields:    
  57. Itzkan I, Pincus G. 1.0621-micro He-Ne gas laser. Appl Opt. 1966 Feb 01; 5(2):349. PMID: 20048847.
    Citations:    Fields:    
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Itzkan's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (146)
Co-Authors (19)
Similar People (60)
Same Department 
Physical Neighbors
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.