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Rodrigo Noseda, PH.D.

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Research
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  1. R01NS104296 (NOSEDA, RODRIGO) Dec 1, 2017 - Nov 30, 2022
    NIH/NINDS
    Pathophysiology of Occipital Migraine
    Role: Principal Investigator
  2. R21NS090254 (NOSEDA, RODRIGO) Jul 15, 2015 - Jun 30, 2017
    NIH/NINDS
    Neural Basis of Occipital Headache
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Bernstein CA, Nir RR, Noseda R, Fulton AB, Huntington S, Lee AJ, Bertisch SM, Hovaguimian A, Buettner C, Borsook D, Burstein R. The migraine eye: distinct rod-driven retinal pathways' response to dim light challenges the visual cortex hyperexcitability theory. Pain. 2019 Mar; 160(3):569-578. PMID: 30376534.
    Citations:    Fields:    
  2. Burstein R, Noseda R, Fulton AB. Neurobiology of Photophobia. J Neuroophthalmol. 2019 Mar; 39(1):94-102. PMID: 30762717.
    Citations:    
  3. Noseda R, Melo-Carrillo A, Nir RR, Strassman AM, Burstein R. Non-Trigeminal Nociceptive Innervation of the Posterior Dura: Implications to Occipital Headache. J Neurosci. 2019 Mar 06; 39(10):1867-1880. PMID: 30622169.
    Citations:    Fields:    
  4. Nir RR, Lee AJ, Huntington S, Noseda R, Bernstein CA, Fulton AB, Bertisch SM, Hovaguimian A, Buettner C, Borsook D, Burstein R. Color-selective photophobia in ictal vs interictal migraineurs and in healthy controls. Pain. 2018 Oct; 159(10):2030-2034. PMID: 29905657.
    Citations:    Fields:    
  5. Younis S, Hougaard A, Noseda R, Ashina M. Current understanding of thalamic structure and function in migraine. Cephalalgia. 2018 Aug 04; 333102418791595. PMID: 30079744.
    Citations:    Fields:    
  6. Noseda R, Copenhagen D, Burstein R. Current understanding of photophobia, visual networks and headaches. Cephalalgia. 2018 Jan 01; 333102418784750. PMID: 29940781.
    Citations: 1     Fields:    
  7. Melo-Carrillo A, Strassman AM, Nir RR, Schain AJ, Noseda R, Stratton J, Burstein R. Fremanezumab-A Humanized Monoclonal Anti-CGRP Antibody-Inhibits Thinly Myelinated (Ad) But Not Unmyelinated (C) Meningeal Nociceptors. J Neurosci. 2017 11 01; 37(44):10587-10596. PMID: 28972120.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  8. Noseda R, Lee AJ, Nir RR, Bernstein CA, Kainz VM, Bertisch SM, Buettner C, Borsook D, Burstein R. Neural mechanism for hypothalamic-mediated autonomic responses to light during migraine. Proc Natl Acad Sci U S A. 2017 07 11; 114(28):E5683-E5692. PMID: 28652355.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  9. Melo-Carrillo A, Noseda R, Nir RR, Schain AJ, Stratton J, Strassman AM, Burstein R. Selective Inhibition of Trigeminovascular Neurons by Fremanezumab: A Humanized Monoclonal Anti-CGRP Antibody. J Neurosci. 2017 07 26; 37(30):7149-7163. PMID: 28642283.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  10. Noseda R, Borsook D, Burstein R. Neuropeptides and Neurotransmitters That Modulate Thalamo-Cortical Pathways Relevant to Migraine Headache. Headache. 2017 May; 57 Suppl 2:97-111. PMID: 28485844.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  11. Hodkinson DJ, Wilcox SL, Veggeberg R, Noseda R, Burstein R, Borsook D, Becerra L. Increased Amplitude of Thalamocortical Low-Frequency Oscillations in Patients with Migraine. J Neurosci. 2016 07 27; 36(30):8026-36. PMID: 27466345.
    Citations: 6     Fields:    Translation:Humans
  12. Noseda R, Bernstein CA, Nir RR, Lee AJ, Fulton AB, Bertisch SM, Hovaguimian A, Cestari DM, Saavedra-Walker R, Borsook D, Doran BL, Buettner C, Burstein R. Migraine photophobia originating in cone-driven retinal pathways. Brain. 2016 07; 139(Pt 7):1971-86. PMID: 27190022.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  13. Burstein R, Noseda R, Borsook D. Migraine: multiple processes, complex pathophysiology. J Neurosci. 2015 Apr 29; 35(17):6619-29. PMID: 25926442.
    Citations: 35     Fields:    Translation:HumansCells
  14. Noseda R, Kainz V, Borsook D, Burstein R. Neurochemical pathways that converge on thalamic trigeminovascular neurons: potential substrate for modulation of migraine by sleep, food intake, stress and anxiety. PLoS One. 2014; 9(8):e103929. PMID: 25090640.
    Citations: 16     Fields:    Translation:AnimalsCells
  15. Noseda R, Burstein R. Migraine pathophysiology: anatomy of the trigeminovascular pathway and associated neurological symptoms, CSD, sensitization and modulation of pain. Pain. 2013 Dec; 154 Suppl 1. PMID: 24347803.
    Citations: 23     Fields:    
  16. Noseda R. Unanswered questions in headache: so what is photophobia, anyway? Headache. 2013 Nov-Dec; 53(10):1679-80. PMID: 24266339.
    Citations: 1     Fields:    Translation:Humans
  17. Noseda R, Burstein R. Migraine pathophysiology: anatomy of the trigeminovascular pathway and associated neurological symptoms, cortical spreading depression, sensitization, and modulation of pain. Pain. 2013 Dec; 154 Suppl 1:S44-53. PMID: 23891892.
    Citations: 72     Fields:    Translation:HumansAnimals
  18. Kagan R, Kainz V, Burstein R, Noseda R. Hypothalamic and basal ganglia projections to the posterior thalamus: possible role in modulation of migraine headache and photophobia. Neuroscience. 2013 Sep 17; 248:359-68. PMID: 23806720.
    Citations: 17     Fields:    Translation:AnimalsCells
  19. Robert C, Bourgeais L, Arreto CD, Condes-Lara M, Noseda R, Jay T, Villanueva L. Paraventricular hypothalamic regulation of trigeminovascular mechanisms involved in headaches. J Neurosci. 2013 May 15; 33(20):8827-40. PMID: 23678125.
    Citations: 22     Fields:    Translation:AnimalsCells
  20. Levy D, Moskowitz MA, Noseda R, Burstein R. Activation of the migraine pain pathway by cortical spreading depression: do we need more evidence? Cephalalgia. 2012 May; 32(7):581-2. PMID: 21996564.
    Citations: 3     Fields:    Translation:Animals
  21. Noseda R, Jakubowski M, Kainz V, Borsook D, Burstein R. Cortical projections of functionally identified thalamic trigeminovascular neurons: implications for migraine headache and its associated symptoms. J Neurosci. 2011 Oct 05; 31(40):14204-17. PMID: 21976505.
    Citations: 36     Fields:    Translation:AnimalsCells
  22. Noseda R, Burstein R. Advances in understanding the mechanisms of migraine-type photophobia. Curr Opin Neurol. 2011 Jun; 24(3):197-202. PMID: 21467933.
    Citations: 23     Fields:    Translation:HumansAnimals
  23. Zhang X, Levy D, Kainz V, Noseda R, Jakubowski M, Burstein R. Activation of central trigeminovascular neurons by cortical spreading depression. Ann Neurol. 2011 May; 69(5):855-65. PMID: 21416489.
    Citations: 66     Fields:    Translation:AnimalsCells
  24. Noseda R, Constandil L, Bourgeais L, Chalus M, Villanueva L. Changes of meningeal excitability mediated by corticotrigeminal networks: a link for the endogenous modulation of migraine pain. J Neurosci. 2010 Oct 27; 30(43):14420-9. PMID: 20980599.
    Citations: 23     Fields:    Translation:AnimalsCells
  25. Zhang X, Levy D, Noseda R, Kainz V, Jakubowski M, Burstein R. Activation of meningeal nociceptors by cortical spreading depression: implications for migraine with aura. J Neurosci. 2010 Jun 30; 30(26):8807-14. PMID: 20592202.
    Citations: 78     Fields:    Translation:AnimalsCells
  26. Noseda R, Kainz V, Jakubowski M, Gooley JJ, Saper CB, Digre K, Burstein R. A neural mechanism for exacerbation of headache by light. Nat Neurosci. 2010 Feb; 13(2):239-45. PMID: 20062053.
    Citations: 105     Fields:    Translation:HumansAnimalsCells
  27. Noseda R, Monconduit L, Constandil L, Chalus M, Villanueva L. Central nervous system networks involved in the processing of meningeal and cutaneous inputs from the ophthalmic branch of the trigeminal nerve in the rat. Cephalalgia. 2008 Aug; 28(8):813-24. PMID: 18498395.
    Citations: 3     Fields:    Translation:Animals
  28. Noseda R, Hernández A, Valladares L, Mondaca M, Laurido C, Soto-Moyano R. Melatonin-induced inhibition of spinal cord synaptic potentiation in rats is MT2 receptor-dependent. Neurosci Lett. 2004 Apr 22; 360(1-2):41-4. PMID: 15082174.
    Citations: 5     Fields:    Translation:AnimalsCells
  29. Mondaca M, Hernández A, Valladares L, Sierralta W, Noseda R, Soto-Moyano R. Involvement of melatonin metabolites in the long-term inhibitory effect of the hormone on rat spinal nociceptive transmission. Pharmacol Biochem Behav. 2004 Feb; 77(2):275-9. PMID: 14751455.
    Citations:    Fields:    Translation:AnimalsCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.