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Frances J. Hayes, M.B.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DK071168 (PITTELOUD, NELLY) Jul 1, 2006 - Jun 30, 2011
    NIH/NIDDK
    Modulation of Insulin Action by Testosterone in Men
    Role: Co-Principal Investigator
  2. R03DK064276 (HAYES, FRANCES J) Feb 1, 2004 - Nov 30, 2006
    NIH/NIDDK
    INTERPLAY BETWEEN GONADAL STEROIDS AND INSULIN IN MEN
    Role: Principal Investigator
  3. K23DK002858 (HAYES, FRANCES J) Jun 1, 2000 - Mar 31, 2005
    NIH/NIDDK
    INTERPLAY BETWEEN GONADAL STEROIDS AND INSULIN IN MEN
    Role: Principal Investigator
  4. M01RR001066 (SLAVIN, PETER L) Dec 1, 1997 - Nov 30, 2007
    NIH/NCRR
    General Clinical Research Center
    Role: Co-Principal Investigator
  5. P41RR007707 (MOFFAT, JOHN KEITH) Sep 15, 1992 - Jul 31, 2013
    NIH/NCRR
    BioCARS: A Synchroton Structural Biology Resource
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Abbott BP, Abbott R, Abbott TD, Abraham S, Acernese F, Ackley K, Adams C, Adhikari RX, Adya VB, Affeldt C, Agathos M, Agatsuma K, Aggarwal N, Aguiar OD, Aiello L, Ain A, Ajith P, Allen G, Allocca A, Aloy MA, Altin PA, Amato A, Anand S, Ananyeva A, Anderson SB, Anderson WG, Angelova SV, Antier S, Appert S, Arai K, Araya MC, Areeda JS, Arène M, Arnaud N, Aronson SM, Arun KG, Ascenzi S, Ashton G, Aston SM, Astone P, Aubin F, Aufmuth P, AultONeal K, Austin C, Avendano V, Avila-Alvarez A, Babak S, Bacon P, Badaracco F, Bader MKM, Bae S, Baird J, Baker PT, Baldaccini F, Ballardin G, Ballmer SW, Bals A, Banagiri S, Barayoga JC, Barbieri C, Barclay SE, Barish BC, Barker D, Barkett K, Barnum S, Barone F, Barr B, Barsotti L, Barsuglia M, Barta D, Bartlett J, Bartos I, Bassiri R, Basti A, Bawaj M, Bayley JC, Bazzan M, Bécsy B, Bejger M, Belahcene I, Bell AS, Beniwal D, Benjamin MG, Berger BK, Bergmann G, Bernuzzi S, Berry CPL, Bersanetti D, Bertolini A, Betzwieser J, Bhandare R, Bidler J, Biggs E, Bilenko IA, Bilgili SA, Billingsley G, Birney R, Birnholtz O, Biscans S, Bischi M, Biscoveanu S, Bisht A, Bitossi M, Bizouard MA, Blackburn JK, Blackman J, Blair CD, Blair DG, Blair RM, Bloemen S, Bobba F, Bode N, Boer M, Boetzel Y, Bogaert G, Bondu F, Bonnand R, Booker P, Boom BA, Bork R, Boschi V, Bose S, Bossilkov V, Bosveld J, Bouffanais Y, Bozzi A, Bradaschia C, Brady PR, Bramley A, Branchesi M, Brau JE, Breschi M, Briant T, Briggs JH, Brighenti F, Brillet A, Brinkmann M, Brockill P, Brooks AF, Brooks J, Brown DD, Brunett S, Buikema A, Bulik T, Bulten HJ, Buonanno A, Buskulic D, Buy C, Byer RL, Cabero M, Cadonati L, Cagnoli G, Cahillane C, Calderón Bustillo J, Callister TA, Calloni E, Camp JB, Campbell WA, Cannon KC, Cao H, Cao J, Carapella G, Carbognani F, Caride S, Carney MF, Carullo G, Casanueva Diaz J, Casentini C, Caudill S, Cavaglià M, Cavalier F, Cavalieri R, Cella G, Cerdá-Durán P, Cesarini E, Chaibi O, Chakravarti K, Chamberlin SJ, Chan M, Chao S, Charlton P, Chase EA, Chassande-Mottin E, Chatterjee D, Chaturvedi M, Chatziioannou K, Cheeseboro BD, Chen HY, Chen X, Chen Y, Cheng HP, Cheong CK, Chia HY, Chiadini F, Chincarini A, Chiummo A, Cho G, Cho HS, Cho M, Christensen N, Chu Q, Chua S, Chung KW, Chung S, Ciani G, Cieslar M, Ciobanu AA, Ciolfi R, Cipriano F, Cirone A, Clara F, Clark JA, Clearwater P, Cleva F, Coccia E, Cohadon PF, Cohen D, Colleoni M, Collette CG, Collins C, Colpi M, Cominsky LR, Constancio M, Conti L, Cooper SJ, Corban P, Corbitt TR, Cordero-Carrión I, Corezzi S, Corley KR, Cornish N, Corre D, Corsi A, Cortese S, Costa CA, Cotesta R, Coughlin MW, Coughlin SB, Coulon JP, Countryman ST, Couvares P, Covas PB, Cowan EE, Coward DM, Cowart MJ, Coyne DC, Coyne R, Creighton JDE, Creighton TD, Cripe J, Croquette M, Crowder SG, Cullen TJ, Cumming A, Cunningham L, Cuoco E, Canton TD, Dálya G, D'Angelo B, Danilishin SL, D'Antonio S, Danzmann K, Dasgupta A, Da Silva Costa CF, Datrier LEH, Dattilo V, Dave I, Davier M, Davis D, Daw EJ, DeBra D, Deenadayalan M, Degallaix J, De Laurentis M, Deléglise S, Del Pozzo W, DeMarchi LM, Demos N, Dent T, De Pietri R, De Rosa R, De Rossi C, DeSalvo R, de Varona O, Dhurandhar S, Díaz MC, Dietrich T, Di Fiore L, DiFronzo C, Di Giorgio C, Di Giovanni F, Di Giovanni M, Di Girolamo T, Di Lieto A, Ding B, Di Pace S, Di Palma I, Di Renzo F, Divakarla AK, Dmitriev A, Doctor Z, Donovan F, Dooley KL, Doravari S, Dorrington I, Downes TP, Drago M, Driggers JC, Du Z, Ducoin JG, Dupej P, Durante O, Dwyer SE, Easter PJ, Eddolls G, Edo TB, Effler A, Ehrens P, Eichholz J, Eikenberry SS, Eisenmann M, Eisenstein RA, Errico L, Essick RC, Estelles H, Estevez D, Etienne ZB, Etzel T, Evans M, Evans TM, Fafone V, Fairhurst S, Fan X, Farinon S, Farr B, Farr WM, Fauchon-Jones EJ, Favata M, Fays M, Fazio M, Fee C, Feicht J, Fejer MM, Feng F, Fernandez-Galiana A, Ferrante I, Ferreira EC, Ferreira TA, Fidecaro F, Fiori I, Fiorucci D, Fishbach M, Fisher RP, Fishner JM, Fittipaldi R, Fitz-Axen M, Fiumara V, et al. Search for Subsolar Mass Ultracompact Binaries in Advanced LIGO's Second Observing Run. Phys Rev Lett. 2019 Oct 18; 123(16):161102. PMID: 31702344.
    Citations:    
  2. Jafri RZ, McNamara EA, Snyder EA, Shah U, Singh I, Hayes FJ, Lin AE, Levitsky LL. Further Delineation of Liver Involvement in Girls and Women with Turner Syndrome: Case Report of a 2-Year-Old with Liver Dysfunction and Review of Patients Followed in the MassGeneral Hospital Turner Syndrome Clinic. Horm Res Paediatr. 2019; 92(5):328-334. PMID: 31563903.
    Citations:    
  3. Lin AE, Prakash SK, Andersen NH, Viuff MH, Levitsky LL, Rivera-Davila M, Crenshaw ML, Hansen L, Colvin MK, Hayes FJ, Lilly E, Snyder EA, Nader-Eftekhari S, Aldrich MB, Bhatt AB, Prager LM, Arenivas A, Skakkebaek A, Steeves MA, Kreher JB, Gravholt CH. Recognition and management of adults with Turner syndrome: From the transition of adolescence through the senior years. Am J Med Genet A. 2019 10; 179(10):1987-2033. PMID: 31418527.
    Citations:    
  4. Dwyer AA, Chavan NR, Lewkowitz-Shpuntoff H, Plummer L, Hayes FJ, Seminara SB, Crowley WF, Pitteloud N, Balasubramanian R. Functional Hypogonadotropic Hypogonadism in Men: Underlying Neuroendocrine Mechanisms and Natural History. J Clin Endocrinol Metab. 2019 08 01; 104(8):3403-3414. PMID: 31220265.
    Citations:    
  5. O'Connor MJ, Snyder EA, Hayes FJ. Klinefelter Syndrome and Diabetes. Curr Diab Rep. 2019 07 31; 19(9):71. PMID: 31367971.
    Citations:    
  6. Jones KL, McNamara EA, Longoni M, Miller DE, Rohanizadegan M, Newman LA, Hayes F, Levitsky LL, Herrington BL, Lin AE. Dual diagnoses in 152 patients with Turner syndrome: Knowledge of the second condition may lead to modification of treatment and/or surveillance. Am J Med Genet A. 2018 11; 176(11):2435-2445. PMID: 30079495.
    Citations:    
  7. Bhasin S, Brito JP, Cunningham GR, Hayes FJ, Hodis HN, Matsumoto AM, Snyder PJ, Swerdloff RS, Wu FC, Yialamas MA. Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2018 05 01; 103(5):1715-1744. PMID: 29562364.
    Citations: 3     Fields:    Translation:Humans
  8. Bui HN, Sluss PM, Hayes FJ, Blincko S, Knol DL, Blankenstein MA, Heijboer AC. Testosterone, free testosterone, and free androgen index in women: Reference intervals, biological variation, and diagnostic value in polycystic ovary syndrome. Clin Chim Acta. 2015 Oct 23; 450:227-32. PMID: 26327459.
    Citations: 2     Fields:    Translation:Humans
  9. Levitsky LL, Luria AH, Hayes FJ, Lin AE. Turner syndrome: update on biology and management across the life span. Curr Opin Endocrinol Diabetes Obes. 2015 Feb; 22(1):65-72. PMID: 25517026.
    Citations: 5     Fields:    Translation:Humans
  10. Hayes FJ. Widespread use of performance-enhancing drugs-an inconvenient truth. Endocr Rev. 2014 Dec; 35(6):E1-2. PMID: 25423333.
    Citations:    Fields:    Translation:HumansPHPublic Health
  11. Dwyer AA, Sykiotis GP, Hayes FJ, Boepple PA, Lee H, Loughlin KR, Dym M, Sluss PM, Crowley WF, Pitteloud N. Trial of recombinant follicle-stimulating hormone pretreatment for GnRH-induced fertility in patients with congenital hypogonadotropic hypogonadism. J Clin Endocrinol Metab. 2013 Nov; 98(11):E1790-5. PMID: 24037890.
    Citations: 7     Fields:    Translation:Humans
  12. Caronia LM, Dwyer AA, Hayden D, Amati F, Pitteloud N, Hayes FJ. Abrupt decrease in serum testosterone levels after an oral glucose load in men: implications for screening for hypogonadism. Clin Endocrinol (Oxf). 2013 Feb; 78(2):291-6. PMID: 22804876.
    Citations: 9     Fields:    Translation:Humans
  13. Sidhoum VF, Chan YM, Lippincott MF, Balasubramanian R, Quinton R, Plummer L, Dwyer A, Pitteloud N, Hayes FJ, Hall JE, Martin KA, Boepple PA, Seminara SB. Reversal and relapse of hypogonadotropic hypogonadism: resilience and fragility of the reproductive neuroendocrine system. J Clin Endocrinol Metab. 2014 Mar; 99(3):861-70. PMID: 24423288.
    Citations: 24     Fields:    Translation:Humans
  14. King TF, Hayes FJ. Long-term outcome of idiopathic hypogonadotropic hypogonadism. Curr Opin Endocrinol Diabetes Obes. 2012 Jun; 19(3):204-10. PMID: 22499222.
    Citations: 3     Fields:    Translation:Humans
  15. O'Connell J, Hayes F. Radioiodine therapy for hyperthyroidism. Ir Med J. 2012 Mar; 105(3):69-70. PMID: 22558809.
    Citations:    Fields:    Translation:Humans
  16. Dwyer AA, Hayes FJ, Plummer L, Pitteloud N, Crowley WF. The long-term clinical follow-up and natural history of men with adult-onset idiopathic hypogonadotropic hypogonadism. J Clin Endocrinol Metab. 2010 Sep; 95(9):4235-43. PMID: 20591981.
    Citations: 6     Fields:    Translation:Humans
  17. Bhasin S, Cunningham GR, Hayes FJ, Matsumoto AM, Snyder PJ, Swerdloff RS, Montori VM. Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2010 Jun; 95(6):2536-59. PMID: 20525905.
    Citations: 336     Fields:    Translation:Humans
  18. Rabiee A, Dwyer AA, Caronia LM, Hayes FJ, Yialamas MA, Andersen DK, Thomas B, Torriani M, Elahi D. Impact of acute biochemical castration on insulin sensitivity in healthy adult men. Endocr Res. 2010 May; 35(2):71-84. PMID: 20408755.
    Citations: 3     Fields:    Translation:Humans
  19. Sykiotis GP, Hoang XH, Avbelj M, Hayes FJ, Thambundit A, Dwyer A, Au M, Plummer L, Crowley WF, Pitteloud N. Congenital idiopathic hypogonadotropic hypogonadism: evidence of defects in the hypothalamus, pituitary, and testes. J Clin Endocrinol Metab. 2010 Jun; 95(6):3019-27. PMID: 20382682.
    Citations: 20     Fields:    Translation:Humans
  20. Ahern T, Hayes FJ. Cancer: Risk of hypogonadism in male survivors of childhood cancer. Nat Rev Endocrinol. 2010 Mar; 6(3):129-30. PMID: 20173773.
    Citations:    Fields:    Translation:Humans
  21. Raivio T, Sidis Y, Plummer L, Chen H, Ma J, Mukherjee A, Jacobson-Dickman E, Quinton R, Van Vliet G, Lavoie H, Hughes VA, Dwyer A, Hayes FJ, Xu S, Sparks S, Kaiser UB, Mohammadi M, Pitteloud N. Frequency of Impaired Fibroblast Growth Factor Receptor 1 Signaling as a Cause of Normosmic Idiopathic Hypogonadotropic Hypogonadism. Endocr Rev. 2009 Dec 01; 30(7):934. PMID: 28199515.
    Citations: 1     Fields:    
  22. Pitteloud N, Thambundit A, Dwyer AA, Falardeau JL, Plummer L, Caronia LM, Hayes FJ, Lee H, Boepple PA, Crowley WF. Role of seminiferous tubular development in determining the FSH versus LH responsiveness to GnRH in early sexual maturation. Neuroendocrinology. 2009; 90(3):260-8. PMID: 19829004.
    Citations: 3     Fields:    Translation:Humans
  23. Raivio T, Sidis Y, Plummer L, Chen H, Ma J, Mukherjee A, Jacobson-Dickman E, Quinton R, Van Vliet G, Lavoie H, Hughes VA, Dwyer A, Hayes FJ, Xu S, Sparks S, Kaiser UB, Mohammadi M, Pitteloud N. Impaired fibroblast growth factor receptor 1 signaling as a cause of normosmic idiopathic hypogonadotropic hypogonadism. J Clin Endocrinol Metab. 2009 Nov; 94(11):4380-90. PMID: 19820032.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  24. Morrell MJ, Hayes FJ, Sluss PM, Adams JM, Bhatt M, Ozkara C, Warnock CR, Isojärvi J. Hyperandrogenism, ovulatory dysfunction, and polycystic ovary syndrome with valproate versus lamotrigine. Ann Neurol. 2008 Aug; 64(2):200-11. PMID: 18756476.
    Citations: 8     Fields:    Translation:Humans
  25. Kupelian V, Hayes FJ, Link CL, Rosen R, McKinlay JB. Inverse association of testosterone and the metabolic syndrome in men is consistent across race and ethnic groups. J Clin Endocrinol Metab. 2008 Sep; 93(9):3403-10. PMID: 18559915.
    Citations: 24     Fields:    Translation:Humans
  26. Cole LW, Sidis Y, Zhang C, Quinton R, Plummer L, Pignatelli D, Hughes VA, Dwyer AA, Raivio T, Hayes FJ, Seminara SB, Huot C, Alos N, Speiser P, Takeshita A, Van Vliet G, Pearce S, Crowley WF, Zhou QY, Pitteloud N. Mutations in prokineticin 2 and prokineticin receptor 2 genes in human gonadotrophin-releasing hormone deficiency: molecular genetics and clinical spectrum. J Clin Endocrinol Metab. 2008 Sep; 93(9):3551-9. PMID: 18559922.
    Citations: 75     Fields:    Translation:HumansAnimalsCells
  27. Pitteloud N, Dwyer AA, DeCruz S, Lee H, Boepple PA, Crowley WF, Hayes FJ. The relative role of gonadal sex steroids and gonadotropin-releasing hormone pulse frequency in the regulation of follicle-stimulating hormone secretion in men. J Clin Endocrinol Metab. 2008 Jul; 93(7):2686-92. PMID: 18445673.
    Citations: 15     Fields:    Translation:Humans
  28. Boepple PA, Hayes FJ, Dwyer AA, Raivio T, Lee H, Crowley WF, Pitteloud N. Relative roles of inhibin B and sex steroids in the negative feedback regulation of follicle-stimulating hormone in men across the full spectrum of seminiferous epithelium function. J Clin Endocrinol Metab. 2008 May; 93(5):1809-14. PMID: 18270253.
    Citations: 5     Fields:    Translation:Humans
  29. Joffe H, Hayes FJ. Menstrual cycle dysfunction associated with neurologic and psychiatric disorders: their treatment in adolescents. Ann N Y Acad Sci. 2008; 1135:219-29. PMID: 18574228.
    Citations: 7     Fields:    Translation:Humans
  30. Pitteloud N, Dwyer AA, DeCruz S, Lee H, Boepple PA, Crowley WF, Hayes FJ. Inhibition of luteinizing hormone secretion by testosterone in men requires aromatization for its pituitary but not its hypothalamic effects: evidence from the tandem study of normal and gonadotropin-releasing hormone-deficient men. J Clin Endocrinol Metab. 2008 Mar; 93(3):784-91. PMID: 18073301.
    Citations: 23     Fields:    Translation:Humans
  31. Sluss PM, Hayes FJ, Adams JM, Barnes W, Williams G, Frost S, Ramp J, Pacenti D, Lehotay DC, George S, Ramsay C, Doss RC, Crowley WF. Mass spectrometric and physiological validation of a sensitive, automated, direct immunoassay for serum estradiol using the Architect. Clin Chim Acta. 2008 Feb; 388(1-2):99-105. PMID: 18023274.
    Citations: 13     Fields:    Translation:Humans
  32. Raivio T, Falardeau J, Dwyer A, Quinton R, Hayes FJ, Hughes VA, Cole LW, Pearce SH, Lee H, Boepple P, Crowley WF, Pitteloud N. Reversal of idiopathic hypogonadotropic hypogonadism. N Engl J Med. 2007 Aug 30; 357(9):863-73. PMID: 17761590.
    Citations: 86     Fields:    Translation:Humans
  33. Yialamas MA, Dwyer AA, Hanley E, Lee H, Pitteloud N, Hayes FJ. Acute sex steroid withdrawal reduces insulin sensitivity in healthy men with idiopathic hypogonadotropic hypogonadism. J Clin Endocrinol Metab. 2007 Nov; 92(11):4254-9. PMID: 17726076.
    Citations: 47     Fields:    Translation:Humans
  34. Pitteloud N, Quinton R, Pearce S, Raivio T, Acierno J, Dwyer A, Plummer L, Hughes V, Seminara S, Cheng YZ, Li WP, Maccoll G, Eliseenkova AV, Olsen SK, Ibrahimi OA, Hayes FJ, Boepple P, Hall JE, Bouloux P, Mohammadi M, Crowley W. Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism. J Clin Invest. 2007 Feb; 117(2):457-63. PMID: 17235395.
    Citations: 126     Fields:    Translation:HumansCells
  35. Cerrato F, Shagoury J, Kralickova M, Dwyer A, Falardeau J, Ozata M, Van Vliet G, Bouloux P, Hall JE, Hayes FJ, Pitteloud N, Martin KA, Welt C, Seminara SB. Coding sequence analysis of GNRHR and GPR54 in patients with congenital and adult-onset forms of hypogonadotropic hypogonadism. Eur J Endocrinol. 2006 Nov; 155 Suppl 1:S3-S10. PMID: 17074994.
    Citations: 22     Fields:    Translation:Humans
  36. Pitteloud N, Meysing A, Quinton R, Acierno JS, Dwyer AA, Plummer L, Fliers E, Boepple P, Hayes F, Seminara S, Hughes VA, Ma J, Bouloux P, Mohammadi M, Crowley WF. Mutations in fibroblast growth factor receptor 1 cause Kallmann syndrome with a wide spectrum of reproductive phenotypes. Mol Cell Endocrinol. 2006 Jul 25; 254-255:60-9. PMID: 16764984.
    Citations: 52     Fields:    Translation:Humans
  37. Bhasin S, Cunningham GR, Hayes FJ, Matsumoto AM, Snyder PJ, Swerdloff RS, Montori VM. Testosterone therapy in adult men with androgen deficiency syndromes: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2006 Jun; 91(6):1995-2010. PMID: 16720669.
    Citations: 140     Fields:    Translation:Humans
  38. Pitteloud N, Acierno JS, Meysing A, Eliseenkova AV, Ma J, Ibrahimi OA, Metzger DL, Hayes FJ, Dwyer AA, Hughes VA, Yialamas M, Hall JE, Grant E, Mohammadi M, Crowley WF. Mutations in fibroblast growth factor receptor 1 cause both Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism. Proc Natl Acad Sci U S A. 2006 Apr 18; 103(16):6281-6. PMID: 16606836.
    Citations: 68     Fields:    Translation:HumansCells
  39. Kumar PA, Pitteloud N, Andrews PA, Dwyer A, Hayes F, Crowley WF, Dym M. Testis morphology in patients with idiopathic hypogonadotropic hypogonadism. Hum Reprod. 2006 Apr; 21(4):1033-40. PMID: 16396935.
    Citations: 3     Fields:    Translation:Humans
  40. Gill S, Hayes FJ, Sluss PM. Issues in Endocrine Immunoassay. Hall JE, Nieman L (eds) Handbook of Diagnostic Endocrinology. 2006.
  41. Pitteloud N, Mootha VK, Dwyer AA, Hardin M, Lee H, Eriksson KF, Tripathy D, Yialamas M, Groop L, Elahi D, Hayes FJ. Relationship between testosterone levels, insulin sensitivity, and mitochondrial function in men. Diabetes Care. 2005 Jul; 28(7):1636-42. PMID: 15983313.
    Citations: 81     Fields:    Translation:HumansCells
  42. Pitteloud N, Hardin M, Dwyer AA, Valassi E, Yialamas M, Elahi D, Hayes FJ. Increasing insulin resistance is associated with a decrease in Leydig cell testosterone secretion in men. J Clin Endocrinol Metab. 2005 May; 90(5):2636-41. PMID: 15713702.
    Citations: 66     Fields:    Translation:HumansCells
  43. Dighe AS, Moy JM, Hayes FJ, Sluss PM. High-resolution reference ranges for estradiol, luteinizing hormone, and follicle-stimulating hormone in men and women using the AxSYM assay system. Clin Biochem. 2005 Feb; 38(2):175-9. PMID: 15642281.
    Citations: 3     Fields:    Translation:Humans
  44. Pitteloud N, Acierno JS, Meysing AU, Dwyer AA, Hayes FJ, Crowley WF. Reversible kallmann syndrome, delayed puberty, and isolated anosmia occurring in a single family with a mutation in the fibroblast growth factor receptor 1 gene. J Clin Endocrinol Metab. 2005 Mar; 90(3):1317-22. PMID: 15613419.
    Citations: 45     Fields:    Translation:HumansCells
  45. Dighe AS, Hayes FJ, Khosravi J, Bodani U, Sluss PM. Comparison of inhibin A immunoassays: recommendation for adoption of standardized reporting. Clin Chem. 2004 Apr; 50(4):767-9. PMID: 15044338.
    Citations:    Fields:    Translation:Humans
  46. Pitteloud N, Villegas J, Dwyer AA, Crowley WF, McPhaul MJ, Hayes FJ. Acute stress masking the biochemical phenotype of partial androgen insensitivity syndrome in a patient with a novel mutation in the androgen receptor. J Clin Endocrinol Metab. 2004 Mar; 89(3):1053-8. PMID: 15001585.
    Citations:    Fields:    Translation:HumansCells
  47. Yialamas MA, Hayes FJ. Androgens and the ageing male and female. Best Pract Res Clin Endocrinol Metab. 2003 Jun; 17(2):223-36. PMID: 12787549.
    Citations: 10     Fields:    Translation:Humans
  48. Gill S, Hayes FJ, Sluss PM. Issues in Endocrine Immunoassay. Hall JE, Nieman L (eds) Handbook of Diagnostic Endocrinology. 2003.
  49. Pitteloud N, Hayes FJ, Dwyer A, Lee H, Crowley WF, Jr. Inhibin B (IB) and FSH have a logarithmic rather than linear relationship in the human male: Evidence from several human models. Abstract OR28-3, Program of the 85th Annual Meeting of the Endocrine Society, Philadelphia. 2003.
  50. Hayes FJ, Hall JE. Hirsutism and virilization. Harris PE, Bouloux P, (eds). Endocrinology in Clinical Practice. 2003; 201-216.
  51. Yialamas MA, Hayes FJ. Androgens and the Aging Male. Axelrod L (ed). Endocrinology Rounds. 2003; 2:1.
  52. Yialamas M, Hayes FJ. Androgens in the Aging Male and Female. Balliere’s Clinical Endocrinology and Metabolism. 2003.
  53. Pitteloud N, Hayes FJ, Dwyer A, Boepple PA, Lee H, Crowley WF. Predictors of outcome of long-term GnRH therapy in men with idiopathic hypogonadotropic hypogonadism. J Clin Endocrinol Metab. 2002 Sep; 87(9):4128-36. PMID: 12213860.
    Citations: 32     Fields:    Translation:HumansCTClinical Trials
  54. Pitteloud N, Hayes FJ, Boepple PA, DeCruz S, Seminara SB, MacLaughlin DT, Crowley WF. The role of prior pubertal development, biochemical markers of testicular maturation, and genetics in elucidating the phenotypic heterogeneity of idiopathic hypogonadotropic hypogonadism. J Clin Endocrinol Metab. 2002 Jan; 87(1):152-60. PMID: 11788640.
    Citations: 32     Fields:    Translation:Humans
  55. Hayes, FJ, Bubley G. . In: UpToDate, Wellesley, MA 2002. Effects of cytotoxic agents on gonadal function in adult men. UpToDate, Rose, BD (Ed). 2002.
  56. Hayes FJ, Pitteloud N. . In: , . 2002. Hypogonadotropic Hypogonadism and Gonadotropin Therapy. McLachlan R (ed). The Endocrinology of the Male. 2002.
  57. Pitteloud N, Dwyer A, Hayes FJ. Impact of insulin resistance on testosterone secretion in the male: evidence of a dual defect in the HPG axis. Abstract OR26-3, Program of the 84th Annual Meeting of the Endocrine Society, San Francisco. 2002.
  58. Hayes FJ, Gill S, Sluss PM. Reproductive Endocrinology. Lewandrowski K (ed) Clinical Chemistry: Laboratory Management and Clinical Correlations. 2002; 625-638.
  59. Hayes FJ, Pitteloud N, DeCruz S, Crowley WF, Boepple PA. Importance of inhibin B in the regulation of FSH secretion in the human male. J Clin Endocrinol Metab. 2001 Nov; 86(11):5541-6. PMID: 11701733.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  60. Pitteloud N, Boepple PA, DeCruz S, Valkenburgh SB, Crowley WF, Hayes FJ. The fertile eunuch variant of idiopathic hypogonadotropic hypogonadism: spontaneous reversal associated with a homozygous mutation in the gonadotropin-releasing hormone receptor. J Clin Endocrinol Metab. 2001 Jun; 86(6):2470-5. PMID: 11397842.
    Citations: 26     Fields:    Translation:HumansCells
  61. Beranova M, Oliveira LM, Bédécarrats GY, Schipani E, Vallejo M, Ammini AC, Quintos JB, Hall JE, Martin KA, Hayes FJ, Pitteloud N, Kaiser UB, Crowley WF, Seminara SB. Prevalence, phenotypic spectrum, and modes of inheritance of gonadotropin-releasing hormone receptor mutations in idiopathic hypogonadotropic hypogonadism. J Clin Endocrinol Metab. 2001 Apr; 86(4):1580-8. PMID: 11297587.
    Citations: 51     Fields:    Translation:HumansAnimalsCells
  62. Oliveira LM, Seminara SB, Beranova M, Hayes FJ, Valkenburgh SB, Schipani E, Costa EM, Latronico AC, Crowley WF, Vallejo M. The importance of autosomal genes in Kallmann syndrome: genotype-phenotype correlations and neuroendocrine characteristics. J Clin Endocrinol Metab. 2001 Apr; 86(4):1532-8. PMID: 11297579.
    Citations: 43     Fields:    Translation:Humans
  63. Hayes FJ, DeCruz S, Seminara SB, Boepple PA, Crowley WF. Differential regulation of gonadotropin secretion by testosterone in the human male: absence of a negative feedback effect of testosterone on follicle-stimulating hormone secretion. J Clin Endocrinol Metab. 2001 Jan; 86(1):53-8. PMID: 11231978.
    Citations: 25     Fields:    Translation:Humans
  64. Hayes FJ. Advances in Androgen Therapy in the Male. Harvard Medical School Clinical Endocrinology Update. 2001.
  65. Hayes FJ. . In: . Philadelphia: ; 2001;8:301-306. Androgen replacement in the male: recent studies. Hall JE (ed). Current Opinion in Endocrinology and Diabetes. 2001; 8:301-306.
  66. Pitteloud N, Hayes FJ, Boepple PA, DeCruz S, Crowley, WF, Jr. Intragonadal secretion of testosterone (T) limits Sertoli cell secretion of inhibin B in the human male. Abstract OR-11, Program of the 83rd Annual Meeting of the Endocrine Society, Denver. 2001.
  67. Hayes FJ, Crowley WF, Jr. State of the Art Management of Infertility: What every Practicing Physician Needs to Know. “Masters of Medicine” Health Science Center for Continuing Medical Education Video Series. 2000.
  68. Seminara SB, Oliveira LM, Beranova M, Hayes FJ, Crowley WF. Genetics of hypogonadotropic hypogonadism. J Endocrinol Invest. 2000 Oct; 23(9):560-5. PMID: 11079449.
    Citations: 7     Fields:    Translation:Humans
  69. Hayes FJ. Testosterone--fountain of youth or drug of abuse? J Clin Endocrinol Metab. 2000 Sep; 85(9):3020-3. PMID: 10999779.
    Citations: 2     Fields:    Translation:Humans
  70. Hayes FJ, Seminara SB, Decruz S, Boepple PA, Crowley WF. Aromatase inhibition in the human male reveals a hypothalamic site of estrogen feedback. J Clin Endocrinol Metab. 2000 Sep; 85(9):3027-35. PMID: 10999781.
    Citations: 35     Fields:    Translation:HumansCTClinical Trials
  71. Suliman AM, al-saber F, Hayes F, Fiad T, Culliton M, Cunningham S, McKenna TJ. Hyperprolactinaemia: analysis of presentation, diagnosis and treatment in the endocrine service of a general hospital. Ir Med J. 2000 May; 93(3):74-6. PMID: 10967851.
    Citations:    Fields:    Translation:Humans
  72. Hayes F, Cayanan C, Barillà D, Monteiro AN. Functional assay for BRCA1: mutagenesis of the COOH-terminal region reveals critical residues for transcription activation. Cancer Res. 2000 May 01; 60(9):2411-8. PMID: 10811118.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  73. Hayes FJ, Boepple PA, DeCruz, Seminara SB, Crowley Jr. WF. Sex steroid and inhibin regulation of gonadotropins in the human male. Abstract OR-1359, Program of the 82 nd Annual Meeting of the Endocrine Society, Toronto. 2000.
  74. Hayes FJ. Approach to the Infertile Male. Humes HD, ed. Kelley’s Textbook of Internal Medicine. 2000; 2628-2630.
  75. Hayes FJ, Fiad TM, McKenna TJ. Gender difference in the response of growth hormone (GH)-deficient adults to GH therapy. Metabolism. 1999 Mar; 48(3):308-13. PMID: 10094105.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  76. Hayes FJ, McNicholl DJ, Schoenfeld D, Marsh EE, Hall JE. Free alpha-subunit is superior to luteinizing hormone as a marker of gonadotropin-releasing hormone despite desensitization at fast pulse frequencies. J Clin Endocrinol Metab. 1999 Mar; 84(3):1028-36. PMID: 10084591.
    Citations: 21     Fields:    Translation:Humans
  77. Hayes FJ*, Seminara SB. What’s New in the Male? Harvard Medical School Postgraduate Couse in Endocrinology. 1999.
  78. Hayes FJ, Welt CK, Martin KA, Crowley WF, Jr. GnRH deficiency: Differential diagnosis and treatment. Endocrinologist. 1999; 9:36-44.
  79. Hayes FJ, Seminara SB, Crowley WF. Hypogonadotropic hypogonadism. Endocrinol Metab Clin North Am. 1998 Dec; 27(4):739-63, vii. PMID: 9922906.
    Citations: 11     Fields:    Translation:HumansAnimals
  80. Hall JE, Taylor AE, Hayes FJ, Crowley WF. Insights into hypothalamic-pituitary dysfunction in polycystic ovary syndrome. J Endocrinol Invest. 1998 Oct; 21(9):602-11. PMID: 9856414.
    Citations: 17     Fields:    Translation:Humans
  81. Seminara SB, Hayes FJ, Crowley WF. Gonadotropin-releasing hormone deficiency in the human (idiopathic hypogonadotropic hypogonadism and Kallmann's syndrome): pathophysiological and genetic considerations. Endocr Rev. 1998 Oct; 19(5):521-39. PMID: 9793755.
    Citations: 70     Fields:    Translation:HumansAnimalsCells
  82. Hayes FJ, Taylor AE, Martin KA, Hall JE. Use of a gonadotropin-releasing hormone antagonist as a physiologic probe in polycystic ovary syndrome: assessment of neuroendocrine and androgen dynamics. J Clin Endocrinol Metab. 1998 Jul; 83(7):2343-9. PMID: 9661606.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  83. Hayes FJ, Hall JE, Boepple PA, Crowley WF. Clinical review 96: Differential control of gonadotropin secretion in the human: endocrine role of inhibin. J Clin Endocrinol Metab. 1998 Jun; 83(6):1835-41. PMID: 9626105.
    Citations: 9     Fields:    Translation:HumansAnimals
  84. Hayes FJ*, Seminara SB*, Crowley WF, Jr. Hypogonadotropic Hypogonadism. Burger HG, McLachlan RI, eds. Endocrinol Metab Clin North Amer. 1998; 27:739-763.
  85. Hayes FJ, Crowley WF. Gonadotropin pulsations across development. Horm Res. 1998; 49(3-4):163-8. PMID: 9550119.
    Citations: 7     Fields:    Translation:HumansAnimals
  86. Hayes FJ, Hall JE, Crowley WF, Jr. Inhibin secretion in men and women during the menstrual cycle. Filicori M, Flamigni D, eds. Treatment of Infertility: The New Frontiers. 1998; 85-96.
  87. Cao Y, Hallet B, Sherratt DJ, Hayes F. Structure-function correlations in the XerD site-specific recombinase revealed by pentapeptide scanning mutagenesis. J Mol Biol. 1997 Nov 21; 274(1):39-53. PMID: 9398514.
    Citations: 9     Fields:    Translation:Cells
  88. Hayes FJ, Sheahan K, Rajendiran S, McKenna TJ. Virilization in a postmenopausal woman as a result of hilus cell hyperplasia associated with a simple ovarian cyst. Am J Obstet Gynecol. 1997 Mar; 176(3):719-20. PMID: 9077639.
    Citations: 1     Fields:    Translation:Humans
  89. Fiad TM, Cunningham SK, Hayes FJ, McKenna TJ. Effects of nifedipine treatment on the renin-angiotensin-aldosterone axis. J Clin Endocrinol Metab. 1997 Feb; 82(2):457-60. PMID: 9024236.
    Citations: 5     Fields:    Translation:Humans
  90. Seminara SB, Boepple PA, Nachtigall LB, Hayes FJ, LeCain AE, Crowley WF, Jr. Interplay of dose and frequency of GnRH stimulation on pituitary LH responsiveness in the human male. Abstract P1-315, Program of the 79th Annual Meeting of the Endocrine Society, Minneapolis. 1997.
  91. Hayes FJ, Fiad TM, McKenna TJ. Activity of the renin-angiotensin-aldosterone axis is dependent on the occurrence of edema in growth hormone (GH)-deficient adults treated with GH. J Clin Endocrinol Metab. 1997 Jan; 82(1):322-3. PMID: 8989283.
    Citations: 2     Fields:    Translation:Humans
  92. Hayes FJ, Boepple PA, Seminara SB, Nachtigall LB, LeCain AE, Georgopolous N, Crowley WF, Jr. . , Minneapolis, 1997. . GnRH-induced tonic secretion of pituitary free a-subunit secretion persists after acute GnRH withdrawal in GnRH deficient men. Abstract # P1-314, Program of the 79th Annual Meeting of the Endocrine Society, Minneapolis. 1997.
  93. Davis MA, Radnedge L, Martin KA, Hayes F, Youngren B, Austin SJ. The P1 ParA protein and its ATPase activity play a direct role in the segregation of plasmid copies to daughter cells. Mol Microbiol. 1996 Sep; 21(5):1029-36. PMID: 8885272.
    Citations: 29     Fields:    Translation:Cells
  94. Hayes FJ, McKenna TJ. The occurrence of lymphocytic hypophysitis in a first but not subsequent pregnancy. J Clin Endocrinol Metab. 1996 Aug; 81(8):3131-2. PMID: 8768889.
    Citations: 3     Fields:    Translation:HumansCells
  95. Hayes FJ, Sheahan K, Heffernan A, McKenna TJ. Aggressive thyroid cancer associated with toxic nodular goitre. Eur J Endocrinol. 1996 Mar; 134(3):366-70. PMID: 8616537.
    Citations: 2     Fields:    Translation:Humans
  96. Hayes FJ, McKenna TJ. Current concepts on the investigation and treatment of hirsutism. J Ir Coll Physicians Surgeons. 1996; 100-103.
  97. Hayes FJ, Salman R, Daly L, McKenna TJ. Unfavorable association of smoking with glycemic control and longterm complications in IDDM patients diagnosed in the last 10 years. Ir J Med Sci. 1996; 165 (Suppl. 4):84.
  98. McKenna TJ, Hayes FJ. Recent advances in the diagnosis and treatment of polycystic ovary syndrome. Bonnar J, ed. Recent advances in Obstetrics and Gynecology. 1996; 121-138.
  99. Hayes FJ, O'Brien A, O'Brien C, Fitzgerald MX, McKenna MJ. Diabetes mellitus in an adult cystic fibrosis population. Ir Med J. 1995 May-Jun; 88(3):102-4. PMID: 7635678.
    Citations:    Fields:    Translation:HumansPHPublic Health
  100. Hayes FJ, McKenna TJ. The impact of smoking and hypertension on the prevalence of macrovascular complications in NIDDM. Ir J Med Sci. 1995; 164:62.
  101. Hayes FJ, McKenna TJ. The deleterious impact of smoking on macro-vascular disease in NIDDM is poorly responsive to smoking cessation. Program of the 77th Annual Meeting of the Endocrine Society, Washington. 1995; 3:272.
  102. Hayes FJ. An approach to the management of adrenal insufficiency. Ir Med Times. 1995; 29:35.
  103. Hayes FJ, Redmond JM, McKenna MJ. Thoracic polyradiculopathy--abdominal wall swelling and sensory symptoms in diabetes mellitus. Ir Med J. 1994 Sep-Oct; 87(5):150-1. PMID: 7960657.
    Citations:    Fields:    Translation:Humans
  104. Hayes FJ, O'Brien A, O'Brien C, FitzGerald MX, McKenna MJ. Diabetes mellitus in an adult cystic fibrosis population. Ir Med J. 1994 Mar-Apr; 87(2):59-60. PMID: 8194958.
    Citations: 2     Fields:    Translation:Humans
  105. Hayes FJ, Sheahan K, McCabe M, Lenehan P, McKenna TJ. . 1994;140 (Suppl.):P56. Symptomatic postmenopausal severe hyperandrogenemia of ovarian origin. J Endocrinol. 1994; 140 (Suppl.):56.
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