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Fred L. Hacker, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Hou Y, Hermann G, Lewis JH, Aerts HJ, Baldini EH, Chen AB, Colson YL, Hacker FL, Killoran JH, Kozono DE, Wagar M, Wee JO, Mak RH. Clinical Outcomes After Lung Stereotactic Body Radiation Therapy in Patients With or Without a Prior Lung Resection. Am J Clin Oncol. 2018 07; 41(7):695-701. PMID: 27819875.
    Citations:    Fields:    
  2. Han Z, Friesen S, Hacker F, Zygmanski P. Two-argument total scatter factor for small fields simultaneously collimated by MLC and jaws: application to stereotactic radiosurgery and radiotherapy. Phys Med Biol. 2017 12 14; 63(1):015002. PMID: 29106378.
    Citations:    Fields:    Translation:Humans
  3. Hou Y, Lee S, Agrawal V, Romano J, Baldini EH, Chen AB, Kozono DE, Killoran JH, Wagar M, Hacker FL, Aerts HJ, Lewis JH, Mak RH. Inter-scan and inter-observer tumour volume delineation variability on cone beam computed tomography in patients treated with stereotactic body radiation therapy for early-stage non-small cell lung cancer. J Med Imaging Radiat Oncol. 2017 Feb; 61(1):93-98. PMID: 27709803.
    Citations:    Fields:    Translation:Humans
  4. Han Z, Bondeson JC, Lewis JH, Mannarino EG, Friesen SA, Wagar MM, Balboni TA, Alexander BM, Arvold ND, Sher DJ, Hacker FL. Evaluation of initial setup accuracy and intrafraction motion for spine stereotactic body radiation therapy using stereotactic body frames. Pract Radiat Oncol. 2016 Jan-Feb; 6(1):e17-24. PMID: 26603596.
    Citations: 2     Fields:    Translation:Humans
  5. Liu Y, Alexander BM, Chen YH, Horvath MC, Aizer AA, Claus EB, Dunn IF, Golby AJ, Johnson MD, Friesen S, Mannarino EG, Wagar M, Hacker FL, Arvold ND. Salvage whole brain radiotherapy or stereotactic radiosurgery after initial stereotactic radiosurgery for 1-4 brain metastases. J Neurooncol. 2015 Sep; 124(3):429-37. PMID: 26108659.
    Citations: 2     Fields:    Translation:Humans
  6. Hou Y, Aileen C, Kozono D, Killoran J, Wagar M, Lee S, Hacker F, Aerts H, Lewis J, Mak R. SU-E-J-266: Cone Beam Computed Tomography (CBCT) Inter-Scan and Inter-Observer Tumor Volume Variability Assessment in Patients Treated with Stereotactic Body Radiation Therapy (SBRT) for Early Stage Non-Small Cell Lung Cancer (NSCLC). Med Phys. 2015 Jun; 42(6):3328. PMID: 26127657.
    Citations:    
  7. Han Z, Yip S, Lewis J, Mannarino E, Friesen S, Wagar M, Hacker F. SU-E-J-34: Setup Accuracy in Spine SBRT Using CBCT 6D Image Guidance in Comparison with 6D ExacTrac. Med Phys. 2015 Jun; 42(6):3271. PMID: 26127427.
    Citations:    
  8. Rajakesari S, Arvold ND, Jimenez RB, Christianson LW, Horvath MC, Claus EB, Golby AJ, Johnson MD, Dunn IF, Lee EQ, Lin NU, Friesen S, Mannarino EG, Wagar M, Hacker FL, Weiss SE, Alexander BM. Local control after fractionated stereotactic radiation therapy for brain metastases. J Neurooncol. 2014 Nov; 120(2):339-46. PMID: 25059451.
    Citations: 10     Fields:    Translation:Humans
  9. Wagar M, Friesen S, Mannarino E, Hacker F. SU-E-T-106: Development of a Collision Prediction Algorithm for Determining Problematic Geometry for SBRT Treatments Using a Stereotactic Body Frame. Med Phys. 2014 Jun; 41(6):246. PMID: 28037551.
    Citations:    
  10. Coroller TP, Mak RH, Lewis JH, Baldini EH, Chen AB, Colson YL, Hacker FL, Hermann G, Kozono D, Mannarino E, Molodowitch C, Wee JO, Sher DJ, Killoran JH. Low incidence of chest wall pain with a risk-adapted lung stereotactic body radiation therapy approach using three or five fractions based on chest wall dosimetry. PLoS One. 2014; 9(4):e94859. PMID: 24728448.
    Citations: 7     Fields:    Translation:Humans
  11. Hacker F, Friesen S, Mannarino E, Wagar M, Lewis J, Lyatskaya Y. SU-E-T-135: A Total Imaging Test Sequence to Determine the Isocenter Coordinates of Multi-Modality Imaging Systems On a Stereotactic Linac Relative to the Radiation Isocenter. Med Phys. 2013 Jun; 40(6Part12):235. PMID: 28518964.
    Citations:    
  12. Coroller T, Lewis J, Mak R, Chen A, Hacker F, Kozono D, Mannarino E, Molodowitch C, Killoran J. SU-E-T-694: Correlation Between Geometric Information and Dose Fractionation in Lung SBRT Treatment Plans. Med Phys. 2013 Jun; 40(6Part21):365-366. PMID: 28519454.
    Citations:    
  13. Hacker F, Bondeson J, Lewis J, Mannarino E, Friesen S, Balboni T, Alexander B, Sher D. SU-E-T-401: Evaluation of Initial Setup Accuracy and Intra-Fraction Motion for Spine SBRT Using Stereotactic Body Frames. Med Phys. 2012 Jun; 39(6Part16):3796. PMID: 28517182.
    Citations:    Fields:    
  14. Wagar M, Mannarino E, Friesen S, Hacker F, Lewis J. SU-E-J-148: Fabrication of an Anatomically Realistic Dynamic Respiratory Phantom. Med Phys. 2012 Jun; 39(6Part8):3686-3687. PMID: 28518896.
    Citations:    Fields:    
  15. Lewis J, Mak R, Molodowitch C, Mannarino E, Baldini E, Chen A, Kozono D, Sher D, Hacker F, Killoran J. TU-E-BRB-02: A Decision Support Tool for SBRT Planning Using a Searchable DVH Database. Med Phys. 2012 Jun; 39(6Part24):3908. PMID: 28518686.
    Citations:    Fields:    
  16. James SS, Mishra P, Hacker F, Berbeco RI, Lewis JH. Quantifying ITV instabilities arising from 4DCT: a simulation study using patient data. Phys Med Biol. 2012 Mar 07; 57(5):L1-7. PMID: 22343122.
    Citations: 9     Fields:    Translation:Humans
  17. Kelly PJ, Mannarino E, Lewis JH, Baldini EH, Hacker FL. Total dural irradiation: RapidArc versus static-field IMRT: a case study. Med Dosim. 2012; 37(2):175-81. PMID: 21862313.
    Citations: 6     Fields:    Translation:Humans
  18. Kelly PJ, Lin YB, Yu AY, Ropper AE, Nguyen PL, Marcus KJ, Hacker FL, Weiss SE. Linear accelerator-based stereotactic radiosurgery for brainstem metastases: the Dana-Farber/Brigham and Women's Cancer Center experience. J Neurooncol. 2011 Sep; 104(2):553-7. PMID: 21213018.
    Citations: 16     Fields:    Translation:Humans
  19. Kelly PJ, Lin YB, Yu AY, Alexander BM, Hacker F, Marcus KJ, Weiss SE. Stereotactic irradiation of the postoperative resection cavity for brain metastasis: a frameless linear accelerator-based case series and review of the technique. Int J Radiat Oncol Biol Phys. 2012 Jan 01; 82(1):95-101. PMID: 21168282.
    Citations: 26     Fields:    Translation:Humans
  20. Ramakrishna N, Rosca F, Friesen S, Tezcanli E, Zygmanszki P, Hacker F. A clinical comparison of patient setup and intra-fraction motion using frame-based radiosurgery versus a frameless image-guided radiosurgery system for intracranial lesions. Radiother Oncol. 2010 Apr; 95(1):109-15. PMID: 20116123.
    Citations: 31     Fields:    Translation:Humans
  21. Park SJ, Ionascu D, Hacker F, Mamon H, Berbeco R. Automatic marker detection and 3D position reconstruction using cine EPID images for SBRT verification. Med Phys. 2009 Oct; 36(10):4536-46. PMID: 19928085.
    Citations: 12     Fields:    Translation:Humans
  22. Lyatskaya Y, Kadam D, Levitsky G, Hacker F, Chin L. Evaluation of a new IR-guided system for mechanical QA of linear accelerators. Med Phys. 2008 Nov; 35(11):4816-23. PMID: 19070214.
    Citations:    Fields:    
  23. Lyatskaya Y, Kadam D, Levitsky G, Hacker F, Chin L. Evaluation of a new IR-guided system for mechanical QA of linear acceleratorsa). Med Phys. 2008 Nov; 35(11):4816-4823. PMID: 28524969.
    Citations:    
  24. Berbeco RI, Hacker F, Zatwarnicki C, Park SJ, Ionascu D, O'Farrell D, Mamon HJ. A novel method for estimating SBRT delivered dose with beam's-eye-view images. Med Phys. 2008 Jul; 35(7Part1):3225-3231. PMID: 28513022.
    Citations:    
  25. Berbeco RI, Hacker F, Zatwarnicki C, Park SJ, Ionascu D, O'Farrell D, Mamon HJ. A novel method for estimating SBRT delivered dose with beam's-eye-view images. Med Phys. 2008 Jul; 35(7):3225-31. PMID: 18697547.
    Citations: 4     Fields:    Translation:Humans
  26. Allen AM, Schofield D, Hacker F, Court LE, Czerminska M. Restricted field IMRT dramatically enhances IMRT planning for mesothelioma. Int J Radiat Oncol Biol Phys. 2007 Dec 01; 69(5):1587-92. PMID: 17892915.
    Citations: 13     Fields:    Translation:Humans
  27. Berbeco RI, Hacker F, Ionascu D, Mamon HJ. Clinical feasibility of using an EPID in CINE mode for image-guided verification of stereotactic body radiotherapy. Int J Radiat Oncol Biol Phys. 2007 Sep 01; 69(1):258-66. PMID: 17707280.
    Citations: 16     Fields:    Translation:HumansCTClinical Trials
  28. Park S, Ionascu D, Hacker F, Berbeco R. Automatic Target Position Verification with 3-D Reconstruction of Implanted Markers Using EPID Images. Medical Physics. 2007; 34(6):2334.
  29. Kadam D, Levitsky G, Hacker F, Chin L, Lyatskaya Y. A Novel Infrared Camera System for Mechanical QA of Radiation Treatment Accelerators. Medical Physics. 2007; 34(6):2533.
  30. Czerminska MA, Schofield D, Hacker FL, Baldini EH, Allen A. Restricted Field IMRT Dramatically Enhances IMRT Planning for Mesothelioma Patients. International Journal of Radiation Oncology Biology Physics. 2006; 66(3, Supplement 1):S680.
  31. Rosca F, Lorenz F, Hacker FL, Chin LM, Ramakrishna N, Zygmanski P. An MLC-based linac QA procedure for the characterization of radiation isocenter and room lasers' position. Med Phys. 2006 Jun; 33(6):1780-7. PMID: 16872085.
    Citations: 7     Fields:    
  32. Hacker F, Rosca F, Friesen S, Zygmanski P, Ramakrishna N. Accuracy assessment of a non-invasive image guided system for intra-cranial linac based radiosurgery. Medical Physics. 2006; 33:2066.
  33. Berbeco R, Ionascu D, Hacker F, Lobo J, Mamon H. A novel method for image-guided verification of SBRT with an EPID in cine mode. Medical Physics. 2006; 33:2021.
  34. Schofield D, Court L, Allen A, Hacker F, Czerminska M. Experimental evaluation of the accuracy of contralateral lung dose calculations for IMRT plans. Medical Physics. 2006; 33:2286.
  35. RI Berbeco, F Hacker, D Ionascu, HJ Mamon. A novel method for image-guided verification of hypofractionated extra-cranial radiation therapy with an EPID in cine mode. Poster Presentation, 9th International Workshop on Electronic Portal Imaging. 2006.
  36. Zygmanski P, Hacker F, Friesen S, Rodenbush R, Lu HM, Chin L. Maximum MLC opening effect in dynamic delivery of IMRT: leaf-positional analysis. J Appl Clin Med Phys. 2005; 6(2):33-43. PMID: 15940210.
    Citations:    Fields:    Translation:Humans
  37. Rosca F, Zygmanski P, Lorenz F, Hacker F, Chin L, Friesen S, Petsuksiri J, Shanmugham L, Ramakrishna N. A new linac QA procedure for the characterization of gantry radiation isocenter. Medical Physics. 2005; 32:1990.
  38. Hacker F. Compared with inverse-planning, forward planning is preferred for IMRT stereotactic radiosurgery. For the proposition. Med Phys. 2003 May; 30(5):731-2. PMID: 12772977.
    Citations:    Fields:    
  39. Zygmanski P, Hacker F, Lu H, Chin L. A retrospective analysis of dynamic MLC controller log-file (DynLog TM) data for Novalis system and its implication on the IMRT fluence distribution. Medical Physics. 2003; 30:1361.
  40. Hacker F, Ramakrishna N. Evaluation of prescription normalization to minimize integral normal tissue dose for radiosurgery with the Novalis shaped beam radiosurgery system. Presented at the 6th Congress of the International Stereotactic Radiosurgery Society (ISRS). 2003.
  41. Hacker F, Zygmanski P, Ramakrishna N. A comparison of forward planned IMRT to inverse planned IMRT for stereotactic radiotherapy. Medical Physics. 2002; 29:1367.
  42. Hacker FL, Bellerive MR, Kooy HM, Dutton SC, Shafman TD. Conformal static field stereotactic radiotherapy for larger intracranial lesions. Radiosurgery 1999. 2000; 3:91-99.
  43. Bues M, Kooy HM, Hacker FL, Tarbell NJ, Chapman P, Loeffler JS. MicroIMRT for intracranial tumors - a case study. Radiosurgery 1999. 2000; 3:64-72.
  44. Kooy HM, Hacker FL, Bellerive MR. Jaw and circular collimator. 1999.
  45. Bues M, Kooy HM, Hacker FL, Tarbell NJ, Chapman P, Loeffler JS. Micro-IMRT for stereotactic radiotherapy of intracranial tumors. International Journal of Radiation Oncology Biology Physics. 1999; 45(3 Supplement 1):319.
  46. Hacker F, Bellerive M, Kooy H. Dosimetric comparison of a fast TMR dose algorithm to a full clarkson integration algorithm. Medical Physics. 1998; 25(7):A187.
  47. Hacker FL, Bellerive MR, Kooy HM, Leber ZH, Shrieve DC, Tarbell NJ, Loeffler JS. Study and implementation of a simple beam shaping system for stereotactic radiotherapy. Radiosurgery 1997. 1998; 2:228-235.
  48. Hacker FL, Kooy HM, Bellerive MR, Killoran JH, Leber ZH, Shrieve DC, Tarbell NJ, Loeffler JS. Beam shaping for conformal fractionated stereotactic radiotherapy: a modeling study. Int J Radiat Oncol Biol Phys. 1997 Jul 15; 38(5):1113-21. PMID: 9276379.
    Citations:    Fields:    Translation:Humans
  49. Hacker FL, Bellerive MR, Kooy HM. Implementation of a conformal stereotactic radiosurgery/radiotherapy system. Medical Physics. 1997; 24:971.
  50. Kooy HM, Cosman EE, Harlan RB, Ledoux RJ, Bellerive MR, Hacker FL, Killoran JH, Mannarino EG, Tarbell NJ, Alexander E III, Shrieve DC, Loeffler JS. A dynamic collimator system for conformal stereotactic radiosurgery and radiotherapy. Radiosurgery 1995. 1996; 1:276.
  51. Killoran JH, Kooy HM, Bellerive MR, Hacker FL, Mannarino EG, Shiu AS, Shriever DC, Tarbell NT, Loeffler JS. Treatment planning support for dynamic linac stereotactic delivery. Radiosurgery 1995. 1996; 1:288.
  52. Hacker FL, Kooy HM, Leber ZH, Killoran JH, Bellerive MR, Tarbell NJ, Shrieve DC, Loeffler JS. Conformal stereotactic arc therapy using multiple independent jaws. Medical Physics. 1996; 23:1052.
  53. Antes KJ, Shiu AS, Kooy HM, Hacker FL, Tung SS, Wong J, Ewton JR. Verification of conformal therapy delivered using a miniature multileaf collimator (MMLC) for stereotactic radiosurgery and radiotherapy. Presented at the annual meeting of the AAPM. 1995.
  54. Shiu AS, Kooy HM, Hacker FL, Tung SS, Wong J, Antes K, Sawaya R, Maor MH. Evaluation of a computer-controlled miniature multileaf collimator (MMLC) for stereotactic radiosurgery and radiotherapy. Presented at the 2nd Congress of the International Stereotactic Radiosurgery Society (ISRS). 1995.
  55. HACKER FL. Mode-locking in a grating coupled oscillator. 1994.
  56. Killoran JH, Hacker FL, Walsh JE. A millimeter-wavelength radiation source using a dual-grating resonator. IEEE Transactions on Plasma Science. 1994; 22:530-535.
  57. Adler R, Richter-Sand R, Hacker F, Walsh J, Arman M. Recent multiwave cherenkov generator experiments. Intense Microwave Pulses II. 1994.
  58. Hacker F, Walsh J, Adler R, Richter-Sand R. Multiwave cherenkov generator experiments. Intense Microwave Pulses SPIE 1872. 1993; SPIE 1872:311-314.
  59. Fisch EE, Hacker FL, Walsh JE. Operation of the saphire cerenkov laser. Sixteenth International Conference on Infrared and Millimeter Waves SPIE 1576. 1991; 1576:480-481.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.