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Thomas McCoy Roberts, Ph.D.

Concepts

This page shows the publications Thomas Roberts has written about Protein-Tyrosine Kinases.
Connection Strength

0.726
  1. The cytokine-activated tyrosine kinase JAK2 activates Raf-1 in a p21ras-dependent manner. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11681-6.
    View in: PubMed
    Score: 0.083
  2. The conserved lysine of the catalytic domain of protein kinases is actively involved in the phosphotransfer reaction and not required for anchoring ATP. Proc Natl Acad Sci U S A. 1993 Jan 15; 90(2):442-6.
    View in: PubMed
    Score: 0.064
  3. Characterization of an active, non-myristylated, cytoplasmic form of the lymphoid protein tyrosine kinase pp56lck. Int Immunol. 1991 Jul; 3(7):673-82.
    View in: PubMed
    Score: 0.058
  4. Lessons from polyoma middle T antigen on signaling and transformation: A DNA tumor virus contribution to the war on cancer. Virology. 2009 Feb 20; 384(2):304-16.
    View in: PubMed
    Score: 0.048
  5. Tyrosine phosphorylations in vivo associated with v-fms transformation. Mol Cell Biol. 1988 Jan; 8(1):176-85.
    View in: PubMed
    Score: 0.045
  6. Tyrosine phosphorylation in signal transduction. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 1:161-71.
    View in: PubMed
    Score: 0.045
  7. The Hopscotch Jak kinase requires the Raf pathway to promote blood cell activation and differentiation in Drosophila. Mol Genet Genomics. 2002 Mar; 267(1):57-63.
    View in: PubMed
    Score: 0.030
  8. The activation loop in Lck regulates oncogenic potential by inhibiting basal kinase activity and restricting substrate specificity. Oncogene. 2000 Aug 17; 19(35):3961-70.
    View in: PubMed
    Score: 0.027
  9. Tangled webs: evidence of cross-talk between c-Raf-1 and Akt. Sci STKE. 1999 Dec 21; 1999(13):PE1.
    View in: PubMed
    Score: 0.026
  10. Tyrosine phosphorylation of the proto-oncoprotein Raf-1 is regulated by Raf-1 itself and the phosphatase Cdc25A. Mol Cell Biol. 1999 Jul; 19(7):4819-24.
    View in: PubMed
    Score: 0.025
  11. Cell density modulates protein-tyrosine phosphorylation. J Biol Chem. 1998 Feb 06; 273(6):3408-14.
    View in: PubMed
    Score: 0.023
  12. Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways. Mol Cell Biol. 1997 Mar; 17(3):1562-71.
    View in: PubMed
    Score: 0.021
  13. Intramolecular interactions of the regulatory domains of the Bcr-Abl kinase reveal a novel control mechanism. Structure. 1996 Sep 15; 4(9):1105-14.
    View in: PubMed
    Score: 0.021
  14. A strategy for screening anti-tumor drugs utilizing oncogenes encoded in retroviral vectors. Int J Cancer. 1996 Jun 11; 66(6):753-9.
    View in: PubMed
    Score: 0.020
  15. Identification of Lck-binding elements in tip of herpesvirus saimiri. J Biol Chem. 1995 Sep 01; 270(35):20660-7.
    View in: PubMed
    Score: 0.019
  16. Signal transduction pathways involving the Raf proto-oncogene. Cancer Metastasis Rev. 1994 Mar; 13(1):105-16.
    View in: PubMed
    Score: 0.017
  17. The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction. Proc Natl Acad Sci U S A. 1993 Jun 01; 90(11):5016-20.
    View in: PubMed
    Score: 0.017
  18. Selective association between MHC class I-restricted T cell receptors, CDS, and activated tyrosine kinases on thymocytes undergoing positive selection. J Immunol. 1992 Nov 15; 149(10):3142-9.
    View in: PubMed
    Score: 0.016
  19. Synthetic phosphopeptide immunogens yield activation-specific antibodies to the c-erbB-2 receptor. Proc Natl Acad Sci U S A. 1992 Nov 01; 89(21):10435-9.
    View in: PubMed
    Score: 0.016
  20. Polyomavirus middle T-antigen NPTY mutants. J Virol. 1992 Oct; 66(10):5770-6.
    View in: PubMed
    Score: 0.016
  21. Tyrosine kinase triggering in thymocytes undergoing positive selection. Eur J Immunol. 1992 Sep; 22(9):2289-94.
    View in: PubMed
    Score: 0.016
  22. Purification and initial characterization of the lymphoid-cell protein-tyrosine kinase p56lck from a baculovirus expression system. Proc Natl Acad Sci U S A. 1991 Jul 15; 88(14):6254-8.
    View in: PubMed
    Score: 0.014
  23. An Epstein-Barr virus protein associated with cell growth transformation interacts with a tyrosine kinase. J Virol. 1991 Jul; 65(7):3681-92.
    View in: PubMed
    Score: 0.014
  24. Oncogenes, growth factors, and signal transduction. N Engl J Med. 1989 Nov 16; 321(20):1383-91.
    View in: PubMed
    Score: 0.013
  25. Mechanisms of transformation by polyoma virus middle T antigen. Biochim Biophys Acta. 1989 Feb; 948(3):345-64.
    View in: PubMed
    Score: 0.012
  26. Extracellular calcium mimics the actions of platelet-derived growth factor on mouse fibroblasts. Cell Growth Differ. 1992 Mar; 3(3):157-64.
    View in: PubMed
    Score: 0.004
  27. Presence of an SH2 domain in the actin-binding protein tensin. Science. 1991 May 03; 252(5006):712-5.
    View in: PubMed
    Score: 0.004
  28. A completely transformation-defective point mutant of polyomavirus middle T antigen which retains full associated phosphatidylinositol kinase activity. J Virol. 1990 Sep; 64(9):4454-61.
    View in: PubMed
    Score: 0.003
  29. Modulation of a Mr 175,000 c-neu receptor isoform in G8/DHFR cells by serum starvation. J Biol Chem. 1990 Jun 25; 265(18):10746-51.
    View in: PubMed
    Score: 0.003
  30. Stimulation via CD3-Ti but not CD2 induces rapid tyrosine phosphorylation of a 68-kDa protein in the human Jurkat T cell line. J Immunol. 1990 Jan 15; 144(2):647-52.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.