Thomas McCoy Roberts, Ph.D.
This page shows the publications Thomas Roberts has written about Isoenzymes.
Comparing the roles of the p110a and p110ß isoforms of PI3K in signaling and cancer. Curr Top Microbiol Immunol. 2010; 347:55-77.
Association of Polyomavirus middle tumor antigen with phospholipase C-gamma 1. J Biol Chem. 1995 May 26; 270(21):12331-4.
Should individual PI3 kinase isoforms be targeted in cancer? Curr Opin Cell Biol. 2009 Apr; 21(2):199-208.
PI3 kinases in cancer: from oncogene artifact to leading cancer target. Sci STKE. 2006 Dec 12; 2006(365):pe52.
The p110alpha isoform of PI3K is essential for proper growth factor signaling and oncogenic transformation. Proc Natl Acad Sci U S A. 2006 Oct 31; 103(44):16296-300.
PI3K isoform dependence of PTEN-deficient tumors can be altered by the genetic context. Proc Natl Acad Sci U S A. 2014 Apr 29; 111(17):6395-400.
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