Harvard Catalyst Profiles

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Thomas McCoy Roberts, Ph.D.

Concepts

This page shows the publications Thomas Roberts has written about Binding Sites.
Connection Strength

0.206
  1. The oncogenic properties of mutant p110alpha and p110beta phosphatidylinositol 3-kinases in human mammary epithelial cells. Proc Natl Acad Sci U S A. 2005 Dec 20; 102(51):18443-8.
    View in: PubMed
    Score: 0.040
  2. A new class of mutations reveals a novel function for the original phosphatidylinositol 3-kinase binding site. Proc Natl Acad Sci U S A. 2003 Aug 05; 100(16):9434-9.
    View in: PubMed
    Score: 0.034
  3. The activation loop in Lck regulates oncogenic potential by inhibiting basal kinase activity and restricting substrate specificity. Oncogene. 2000 Aug 17; 19(35):3961-70.
    View in: PubMed
    Score: 0.027
  4. pRB-dependent, J domain-independent function of simian virus 40 large T antigen in override of p53 growth suppression. J Virol. 2000 Jan; 74(2):864-74.
    View in: PubMed
    Score: 0.026
  5. Interaction of the protein kinase Raf-1 with 14-3-3 proteins. Science. 1994 Oct 07; 266(5182):126-9.
    View in: PubMed
    Score: 0.018
  6. The conserved lysine of the catalytic domain of protein kinases is actively involved in the phosphotransfer reaction and not required for anchoring ATP. Proc Natl Acad Sci U S A. 1993 Jan 15; 90(2):442-6.
    View in: PubMed
    Score: 0.016
  7. Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A. Cell. 1990 Jan 12; 60(1):167-76.
    View in: PubMed
    Score: 0.013
  8. 2.6 A resolution crystal structure of helices of the motile major sperm protein (MSP) of Caenorhabditis elegans. J Mol Biol. 2002 May 31; 319(2):491-9.
    View in: PubMed
    Score: 0.008
  9. Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen. Mol Cell Biol. 1997 Sep; 17(9):4979-90.
    View in: PubMed
    Score: 0.006
  10. Intramolecular interactions of the regulatory domains of the Bcr-Abl kinase reveal a novel control mechanism. Structure. 1996 Sep 15; 4(9):1105-14.
    View in: PubMed
    Score: 0.005
  11. Identification of Lck-binding elements in tip of herpesvirus saimiri. J Biol Chem. 1995 Sep 01; 270(35):20660-7.
    View in: PubMed
    Score: 0.005
  12. Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen. Proc Natl Acad Sci U S A. 1994 Jul 05; 91(14):6344-8.
    View in: PubMed
    Score: 0.004
  13. Presence of an SH2 domain in the actin-binding protein tensin. Science. 1991 May 03; 252(5006):712-5.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.