Title Associate Professor of Psychiatry Institution Brigham and Women's Hospital Address 1249 Boylston St Boston MA 02215
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Title
Associate Professor of Radiology
Institution
Brigham and Women's Hospital

Biography
1992 - 1997
BITS Institute Fellowship
1996
Motorola Best Student Thesis Award
2007
O. Hugo Schuk Best Paper Award
2009
Best Tractography Algorithm
2019
Pillar Award in Research Innovation

Overview
My research interests lie in the areas of signal and image-processing, statistics, control theory, computer vision and related applications. Of particular interest to me is the application of mathematics, statistics and control theory to solve problems in medical imaging and computer vision.
My research interests lie in developing smart imaging techniques to understand brain structure and function. My team has developed several compressed sensing algorithms for fast imaging of diffusion MRI — a technology that is now being used to obtain advanced MRI scans of children with ADHD (Attention-deficit Hyperactivity Disorder). My current research focus is on 1). Ultra-high resolution diffusion imaging combining acquisition and reconstruction, 2). estimating tissue microstructure from biophysical and stochastic models of diffusion, and 3). time-series analysis for understanding functional connectivity using fMRI, EEG or MEG data. Clinical research focus includes using and developing sophisticated tractography algorithms for precise targeting of deep-brain stimulation (DBS) and transcranial magnetic stimulation (TMS) in obsessive compulsive disorder (OCD), Parkinson’s and major depressive disorder (MDD). My broad research focus is in the areas of signal and image-processing, statistics, control theory, machine learning, computer vision and related applications to solve inverse problems in medical imaging.

Research
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R01MH125860
(O'DONNELL, LAUREN JEAN)
Jul 1, 2021 - Apr 30, 2026
Mapping the superficial white matter connectome of the human brain using ultra high resolution multi-contrast diffusion MRI
Role: Co-Principal Investigator
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R01MH119222
(RATHI, YOGESH)
Apr 1, 2019 - Jan 31, 2024
Harmonizing multi-site diffusion MRI acquisitions for neuroscientific analysis across ages and brain disorders
Role: Principal Investigator
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R01MH116173
(SETSOMPOP, KAWIN)
Mar 1, 2018 - Jan 31, 2023
Next generation in-vivo diffusion imaging at submillimeter resolution
Role: Co-Principal Investigator
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R01MH111917
(DOUGHERTY, DARIN D)
Sep 19, 2017 - Jun 30, 2021
Patient-specific, Effective, and Rational Functional Connectivity Targeting for DBS in OCD
Role: Co-Principal Investigator
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R01MH097979
(RATHI, YOGESH)
Sep 18, 2012 - Nov 30, 2018
Taking advanced diffusion imaging to the clinic for pediatric patients with ADHD
Role: Principal Investigator

Bibliographic
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