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Yogesh Rathi, Ph.D.

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Biography
1992 - 1997
BITS Institute Fellowship
1996
Motorola Best Student Thesis Award
2007
O. Hugo Schuk Best Paper Award
2009
Best Tractography Algorithm
2019
Pillar Award in Research Innovation

Overview
My research interests lie in the areas of signal and image-processing, statistics, control theory, computer vision and related applications. Of particular interest to me is the application of mathematics, statistics and control theory to solve problems in medical imaging and computer vision.

My research interests lie in developing smart imaging techniques to understand brain structure and function. My team has developed several compressed sensing algorithms for fast imaging of diffusion MRI — a technology that is now being used to obtain advanced MRI scans of children with ADHD (Attention-deficit Hyperactivity Disorder). My current research focus is on 1). Ultra-high resolution diffusion imaging combining acquisition and reconstruction, 2). estimating tissue microstructure from biophysical and stochastic models of diffusion, and 3). time-series analysis for understanding functional connectivity using fMRI, EEG or MEG data. Clinical research focus includes using and developing sophisticated tractography algorithms for precise targeting of deep-brain stimulation (DBS) and transcranial magnetic stimulation (TMS) in obsessive compulsive disorder (OCD), Parkinson’s and major depressive disorder (MDD). My broad research focus is in the areas of signal and image-processing, statistics, control theory, machine learning, computer vision and related applications to solve inverse problems in medical imaging.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01MH132610 (O'DONNELL, LAUREN JEAN) Jun 20, 2023 - Mar 31, 2028
    NIH
    Mapping of the intrinsic and extrinsic cerebellar connectome at ultra high resolution with expert neuroanatomical curation
    Role: Co-Principal Investigator
  2. R01EB032378 (RATHI, YOGESH) Sep 15, 2022 - Jun 30, 2026
    NIH
    Harmonizing data acquisition, reconstruction, and analysis for reproducible, cross-vendor, open source MRI
    Role: Principal Investigator
  3. R01NS125307 (RUSHMORE, RICHARD JARRETT) Jul 1, 2022 - Jun 30, 2027
    NIH
    Unraveling the Superficial White Matter of the Primate Brain: Tracer-Based Histology and dMRI Tractography Validation
    Role: Co-Principal Investigator
  4. R01MH125860 (O'DONNELL, LAUREN JEAN) Jul 1, 2021 - Apr 30, 2026
    NIH
    Mapping the superficial white matter connectome of the human brain using ultra high resolution multi-contrast diffusion MRI
    Role: Co-Principal Investigator
  5. R01MH119222 (RATHI, YOGESH) Apr 1, 2019 - Jan 31, 2025
    NIH
    Harmonizing multi-site diffusion MRI acquisitions for neuroscientific analysis across ages and brain disorders
    Role: Principal Investigator

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Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.