Harvard Catalyst Profiles

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Steven Edward Hyman, M.D.

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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. S07RR018170 (HYMAN, STEVEN E) Sep 1, 2002 - Aug 31, 2006
    NIH
    Enhancement of Human Subject Protection Training
    Role: Principal Investigator
  2. P01DA010160 (GOLDMAN-RAKIC, PATRICIA S) Sep 30, 1995 - Aug 31, 2001
    NIH/NIDA
    CHOLINERGIC AND DOPAMINERGIC SYSTEMS IN THE BRAIN AND MULTIPLE INTERACTIONS
    Role: Co-Principal Investigator
  3. K02DA000257 (HYMAN, STEVEN E) Aug 1, 1995 - Apr 13, 1996
    NIH
    MOLECULAR PLASTICITY TO DRUGS OF ABUSE
    Role: Principal Investigator
  4. P01DA009467 (ROSEN, BRUCE R) Sep 30, 1994 - Jun 30, 2005
    NIH
    FUNCTIONAL BRAIN MAPPING OF COCAINE ACTION
    Role: Co-Principal Investigator
  5. H13SP005874 (HYMAN, STEVEN E) Feb 1, 1993 - Jan 31, 1994
    NIH
    COMNTY PART CONF 'ADDICTION: FROM MOLECULES TO POLICY'
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Nehme R, Pietiläinen O, Artomov M, Tegtmeyer M, Valakh V, Lehtonen L, Bell C, Singh T, Trehan A, Sherwood J, Manning D, Peirent E, Malik R, Guss EJ, Hawes D, Beccard A, Bara AM, Hazelbaker DZ, Zuccaro E, Genovese G, Loboda AA, Neumann A, Lilliehook C, Kuismin O, Hamalainen E, Kurki M, Hultman CM, Kähler AK, Paulo JA, Ganna A, Madison J, Cohen B, McPhie D, Adolfsson R, Perlis R, Dolmetsch R, Farhi S, McCarroll S, Hyman S, Neale B, Barrett LE, Harper W, Palotie A, Daly M, Eggan K. The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia. Nat Commun. 2022 06 27; 13(1):3690. PMID: 35760976; PMCID: PMC9237031.
    Citations:    Fields:    Translation:HumansCells
  2. Kotov R, Cicero DC, Conway CC, DeYoung CG, Dombrovski A, Eaton NR, First MB, Forbes MK, Hyman SE, Jonas KG, Krueger RF, Latzman RD, Li JJ, Nelson BD, Regier DA, Rodriguez-Seijas C, Ruggero CJ, Simms LJ, Skodol AE, Waldman ID, Waszczuk MA, Watson D, Widiger TA, Wilson S, Wright AGC. The Hierarchical Taxonomy of Psychopathology (HiTOP) in psychiatric practice and research. Psychol Med. 2022 07; 52(9):1666-1678. PMID: 35650658.
    Citations:    Fields:    Translation:Humans
  3. Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis G, Zhang W, Adams M, Agartz I, Atkinson EG, Agerbo E, Al Eissa M, Albus M, Alexander M, Alizadeh BZ, Alptekin K, Als TD, Amin F, Arolt V, Arrojo M, Athanasiu L, Azevedo MH, Bacanu SA, Bass NJ, Begemann M, Belliveau RA, Bene J, Benyamin B, Bergen SE, Blasi G, Bobes J, Bonassi S, Braun A, Bressan RA, Bromet EJ, Bruggeman R, Buckley PF, Buckner RL, Bybjerg-Grauholm J, Cahn W, Cairns MJ, Calkins ME, Carr VJ, Castle D, Catts SV, Chambert KD, Chan RCK, Chaumette B, Cheng W, Cheung EFC, Chong SA, Cohen D, Consoli A, Cordeiro Q, Costas J, Curtis C, Davidson M, Davis KL, de Haan L, Degenhardt F, DeLisi LE, Demontis D, Dickerson F, Dikeos D, Dinan T, Djurovic S, Duan J, Ducci G, Dudbridge F, Eriksson JG, Fañanás L, Faraone SV, Fiorentino A, Forstner A, Frank J, Freimer NB, Fromer M, Frustaci A, Gadelha A, Genovese G, Gershon ES, Giannitelli M, Giegling I, Giusti-Rodríguez P, Godard S, Goldstein JI, González Peñas J, González-Pinto A, Gopal S, Gratten J, Green MF, Greenwood TA, Guillin O, Gülöksüz S, Gur RE, Gur RC, Gutiérrez B, Hahn E, Hakonarson H, Haroutunian V, Hartmann AM, Harvey C, Hayward C, Henskens FA, Herms S, Hoffmann P, Howrigan DP, Ikeda M, Iyegbe C, Joa I, Julià A, Kähler AK, Kam-Thong T, Kamatani Y, Karachanak-Yankova S, Kebir O, Keller MC, Kelly BJ, Khrunin A, Kim SW, Klovins J, Kondratiev N, Konte B, Kraft J, Kubo M, Kucinskas V, Kucinskiene ZA, Kusumawardhani A, Kuzelova-Ptackova H, Landi S, Lazzeroni LC, Lee PH, Legge SE, Lehrer DS, Lencer R, Lerer B, Li M, Lieberman J, Light GA, Limborska S, Liu CM, Lönnqvist J, Loughland CM, Lubinski J, Luykx JJ, Lynham A, Macek M, Mackinnon A, Magnusson PKE, Maher BS, Maier W, Malaspina D, Mallet J, Marder SR, Marsal S, Martin AR, Martorell L, Mattheisen M, McCarley RW, McDonald C, McGrath JJ, Medeiros H, Meier S, Melegh B, Melle I, Mesholam-Gately RI, Metspalu A, Michie PT, Milani L, Milanova V, Mitjans M, Molden E, Molina E, Molto MD, Mondelli V, Moreno C, Morley CP, Muntané G, Murphy KC, Myin-Germeys I, Nenadic I, Nestadt G, Nikitina-Zake L, Noto C, Nuechterlein KH, O'Brien NL, O'Neill FA, Oh SY, Olincy A, Ota VK, Pantelis C, Papadimitriou GN, Parellada M, Paunio T, Pellegrino R, Periyasamy S, Perkins DO, Pfuhlmann B, Pietiläinen O, Pimm J, Porteous D, Powell J, Quattrone D, Quested D, Radant AD, Rampino A, Rapaport MH, Rautanen A, Reichenberg A, Roe C, Roffman JL, Roth J, Rothermundt M, Rutten BPF, Saker-Delye S, Salomaa V, Sanjuan J, Santoro ML, Savitz A, Schall U, Scott RJ, Seidman LJ, Sharp SI, Shi J, Siever LJ, Sigurdsson E, Sim K, Skarabis N, Slominsky P, So HC, Sobell JL, Söderman E, Stain HJ, Steen NE, Steixner-Kumar AA, Stögmann E, Stone WS, Straub RE, Streit F, Strengman E, Stroup TS, Subramaniam M, Sugar CA, Suvisaari J, Svrakic DM, Swerdlow NR, Szatkiewicz JP, Ta TMT, Takahashi A, Terao C, Thibaut F, Toncheva D, Tooney PA, Torretta S, Tosato S, Tura GB, Turetsky BI, Üçok A, Vaaler A, van Amelsvoort T, van Winkel R, Veijola J, Waddington J, Walter H, Waterreus A, Webb BT, Weiser M, Williams NM, Witt SH, Wormley BK, Wu JQ, Xu Z, Yolken R, Zai CC, Zhou W, Zhu F, Zimprich F, Atbasoglu EC, Ayub M, et al. Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Nature. 2022 04; 604(7906):502-508. PMID: 35396580; PMCID: PMC9392466.
    Citations: 19     Fields:    Translation:Humans
  4. Johnson MB, Hyman SE. A Critical Perspective on the Synaptic Pruning Hypothesis of Schizophrenia Pathogenesis. Biol Psychiatry. 2022 09 15; 92(6):440-442. PMID: 35105471.
    Citations:    Fields:    
  5. Hyman SE. The familiar dialectic between overclaiming and moral outrage over brain biology: disconnected from what matters. Psychol Med. 2021 12; 51(16):2776-2777. PMID: 34399865; PMCID: PMC8640362.
    Citations:    Fields:    
  6. Turley P, Meyer MN, Wang N, Cesarini D, Hammonds E, Martin AR, Neale BM, Rehm HL, Wilkins-Haug L, Benjamin DJ, Hyman S, Laibson D, Visscher PM. Problems with Using Polygenic Scores to Select Embryos. N Engl J Med. 2021 07 01; 385(1):78-86. PMID: 34192436.
    Citations: 13     Fields:    Translation:Humans
  7. Hyman SE. Use of mouse models to investigate the contributions of CNVs associated with schizophrenia and autism to disease mechanisms. Curr Opin Genet Dev. 2021 06; 68:99-105. PMID: 33957550.
    Citations: 3     Fields:    Translation:HumansAnimals
  8. Hyman SE. PANDAS: Too Narrow a View of the Neuroimmune Landscape. Am J Psychiatry. 2021 01 01; 178(1):5-7. PMID: 33384008.
    Citations: 1     Fields:    Translation:HumansCells
  9. Hyman SE. Wringing Biological Insight From Polygenic Signals. Biol Psychiatry. 2021 01 01; 89(1):8-10. PMID: 33272363.
    Citations:    Fields:    
  10. Cline H, Coolen L, de Vries S, Hyman S, Segal R, Steward O. Recognizing Team Science Contributions in Academic Hiring, Promotion, and Tenure. J Neurosci. 2020 08 26; 40(35):6662-6663. PMID: 32847999.
    Citations: 1     Fields:    Translation:Humans
  11. Waszczuk MA, Eaton NR, Krueger RF, Shackman AJ, Waldman ID, Zald DH, Lahey BB, Patrick CJ, Conway CC, Ormel J, Hyman SE, Fried EI, Forbes MK, Docherty AR, Althoff RR, Bach B, Chmielewski M, DeYoung CG, Forbush KT, Hallquist M, Hopwood CJ, Ivanova MY, Jonas KG, Latzman RD, Markon KE, Mullins-Sweatt SN, Pincus AL, Reininghaus U, South SC, Tackett JL, Watson D, Wright AGC, Kotov R. Redefining phenotypes to advance psychiatric genetics: Implications from hierarchical taxonomy of psychopathology. J Abnorm Psychol. 2020 Feb; 129(2):143-161. PMID: 31804095.
    Citations: 20     Fields:    Translation:Humans
  12. Lam M, Chen CY, Li Z, Martin AR, Bryois J, Ma X, Gaspar H, Ikeda M, Benyamin B, Brown BC, Liu R, Zhou W, Guan L, Kamatani Y, Kim SW, Kubo M, Kusumawardhani AAAA, Liu CM, Ma H, Periyasamy S, Takahashi A, Xu Z, Yu H, Zhu F, Chen WJ, Faraone S, Glatt SJ, He L, Hyman SE, Hwu HG, McCarroll SA, Neale BM, Sklar P, Wildenauer DB, Yu X, Zhang D, Mowry BJ, Lee J, Holmans P, Xu S, Sullivan PF, Ripke S, O'Donovan MC, Daly MJ, Qin S, Sham P, Iwata N, Hong KS, Schwab SG, Yue W, Tsuang M, Liu J, Ma X, Kahn RS, Shi Y, Huang H. Comparative genetic architectures of schizophrenia in East Asian and European populations. Nat Genet. 2019 12; 51(12):1670-1678. PMID: 31740837; PMCID: PMC6885121.
    Citations: 122     Fields:    Translation:Humans
  13. Koopmans F, van Nierop P, Andres-Alonso M, Byrnes A, Cijsouw T, Coba MP, Cornelisse LN, Farrell RJ, Goldschmidt HL, Howrigan DP, Hussain NK, Imig C, de Jong APH, Jung H, Kohansalnodehi M, Kramarz B, Lipstein N, Lovering RC, MacGillavry H, Mariano V, Mi H, Ninov M, Osumi-Sutherland D, Pielot R, Smalla KH, Tang H, Tashman K, Toonen RFG, Verpelli C, Reig-Viader R, Watanabe K, van Weering J, Achsel T, Ashrafi G, Asi N, Brown TC, De Camilli P, Feuermann M, Foulger RE, Gaudet P, Joglekar A, Kanellopoulos A, Malenka R, Nicoll RA, Pulido C, de Juan-Sanz J, Sheng M, Südhof TC, Tilgner HU, Bagni C, Bayés À, Biederer T, Brose N, Chua JJE, Dieterich DC, Gundelfinger ED, Hoogenraad C, Huganir RL, Jahn R, Kaeser PS, Kim E, Kreutz MR, McPherson PS, Neale BM, O'Connor V, Posthuma D, Ryan TA, Sala C, Feng G, Hyman SE, Thomas PD, Smit AB, Verhage M. SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse. Neuron. 2019 07 17; 103(2):217-234.e4. PMID: 31171447; PMCID: PMC6764089.
    Citations: 116     Fields:    Translation:HumansAnimalsCells
  14. Hyman SE. New Evidence for Shared Risk Architecture of Mental Disorders. JAMA Psychiatry. 2019 03 01; 76(3):235-236. PMID: 30649144.
    Citations: 5     Fields:    Translation:Humans
  15. Ramos KM, Grady C, Greely HT, Chiong W, Eberwine J, Farahany NA, Johnson LSM, Hyman BT, Hyman SE, Rommelfanger KS, Serrano EE, Churchill JD, Gordon JA, Koroshetz WJ. The NIH BRAIN Initiative: Integrating Neuroethics and Neuroscience. Neuron. 2019 02 06; 101(3):394-398. PMID: 30731065.
    Citations: 9     Fields:    Translation:Humans
  16. Martin AR, Daly MJ, Robinson EB, Hyman SE, Neale BM. Predicting Polygenic Risk of Psychiatric Disorders. Biol Psychiatry. 2019 07 15; 86(2):97-109. PMID: 30737014; PMCID: PMC6599546.
    Citations: 65     Fields:    Translation:Humans
  17. Greely HT, Grady C, Ramos KM, Chiong W, Eberwine J, Farahany NA, Johnson LSM, Hyman BT, Hyman SE, Rommelfanger KS, Serrano EE. Neuroethics Guiding Principles for the NIH BRAIN Initiative. J Neurosci. 2018 12 12; 38(50):10586-10588. PMID: 30541767; PMCID: PMC6297371.
    Citations: 14     Fields:    Translation:Humans
  18. Sanders SJ, Neale BM, Huang H, Werling DM, An JY, Dong S, Abecasis G, Arguello PA, Blangero J, Boehnke M, Daly MJ, Eggan K, Geschwind DH, Glahn DC, Goldstein DB, Gur RE, Handsaker RE, McCarroll SA, Ophoff RA, Palotie A, Pato CN, Sabatti C, State MW, Willsey AJ, Hyman SE, Addington AM, Lehner T, Freimer NB. Publisher Correction: Whole genome sequencing in psychiatric disorders: the WGSPD consortium. Nat Neurosci. 2018 Jul; 21(7):1017. PMID: 29549319.
    Citations: 2     Fields:    
  19. Hyman SE. The importance of true collaboration in efforts to increase diversity in genetic analyses. Curr Biol. 2018 05 21; 28(10):R598. PMID: 29787720.
    Citations: 1     Fields:    
  20. Farahany NA, Greely HT, Hyman S, Koch C, Grady C, Pa?ca SP, Sestan N, Arlotta P, Bernat JL, Ting J, Lunshof JE, Iyer EPR, Hyun I, Capestany BH, Church GM, Huang H, Song H. The ethics of experimenting with human brain tissue. Nature. 2018 04; 556(7702):429-432. PMID: 29691509.
    Citations: 35     Fields:    Translation:HumansAnimals
  21. Hyman SE. The daunting polygenicity of mental illness: making a new map. Philos Trans R Soc Lond B Biol Sci. 2018 03 19; 373(1742). PMID: 29352030; PMCID: PMC5790829.
    Citations: 17     Fields:    Translation:Humans
  22. Hyman SE. Steven E. Hyman. Curr Biol. 2018 01 08; 28(1):R6-R8. PMID: 29414131.
    Citations:    Fields:    
  23. Sanders SJ, Neale BM, Huang H, Werling DM, An JY, Dong S, Abecasis G, Arguello PA, Blangero J, Boehnke M, Daly MJ, Eggan K, Geschwind DH, Glahn DC, Goldstein DB, Gur RE, Handsaker RE, McCarroll SA, Ophoff RA, Palotie A, Pato CN, Sabatti C, State MW, Willsey AJ, Hyman SE, Addington AM, Lehner T, Freimer NB. Whole genome sequencing in psychiatric disorders: the WGSPD consortium. Nat Neurosci. 2017 12; 20(12):1661-1668. PMID: 29184211.
    Citations: 39     Fields:    Translation:Humans
  24. Hyman S. Biology needs more staff scientists. Nature. 2017 05 16; 545(7654):283-284. PMID: 28516936.
    Citations: 1     Fields:    Translation:Humans
  25. Hyman SE. A Valuable New Direction in Ethical Analysis of Psychiatric Genetics. Am J Bioeth. 2017 04; 17(4):13-15. PMID: 28328368.
    Citations: 1     Fields:    Translation:Humans
  26. Hyman SE. A New Hope for Biological Insights Into Depression. Biol Psychiatry. 2017 02 15; 81(4):280-281. PMID: 28089024.
    Citations:    Fields:    Translation:Humans
  27. Ransom RC, Hunter DJ, Hyman S, Singh G, Ransom SC, Shen EZ, Perez KC, Gillette M, Li J, Liu B, Brunski JB, Helms JA. Axin2-expressing cells execute regeneration after skeletal injury. Sci Rep. 2016 11 17; 6:36524. PMID: 27853243.
    Citations: 13     Fields:    Translation:AnimalsCells
  28. Hyman SE. Back to basics: luring industry back into neuroscience. Nat Neurosci. 2016 10 26; 19(11):1383-1384. PMID: 27786185.
    Citations: 12     Fields:    Translation:HumansAnimals
  29. Hyman SE, Landis SC, Leshner AI. Research Into Brain Disorders as an Example of Targeted Science. JAMA. 2016 Oct 25; 316(16):1673-1674. PMID: 27668392.
    Citations:    Fields:    Translation:Humans
  30. Robinson EB, Neale BM, Hyman SE. Genetic research in autism spectrum disorders. Curr Opin Pediatr. 2015 Dec; 27(6):685-91. PMID: 26371945; PMCID: PMC4650984.
    Citations: 25     Fields:    Translation:Humans
  31. Hyman SE. Enlisting hESCs to Interrogate Genetic Variants Associated with Neuropsychiatric Disorders. Cell Stem Cell. 2015 Sep 03; 17(3):253-4. PMID: 26340523.
    Citations: 1     Fields:    Translation:HumansCells
  32. Hyman SE, Goldberg ME. Protect researchers from harassment. Science. 2015 Jun 12; 348(6240):1216-7. PMID: 26068840.
    Citations:    Fields:    Translation:HumansAnimals
  33. Hyman S. Mental health: depression needs large human-genetics studies. Nature. 2014 Nov 13; 515(7526):189-91. PMID: 25391945.
    Citations: 19     Fields:    Translation:HumansAnimals
  34. Choi DW, Armitage R, Brady LS, Coetzee T, Fisher W, Hyman S, Pande A, Paul S, Potter W, Roin B, Sherer T. Medicines for the mind: policy-based "pull" incentives for creating breakthrough CNS drugs. Neuron. 2014 Nov 05; 84(3):554-63. PMID: 25442934.
    Citations: 24     Fields:    Translation:HumansAnimals
  35. Pankevich DE, Altevogt BM, Dunlop J, Gage FH, Hyman SE. Improving and accelerating drug development for nervous system disorders. Neuron. 2014 Nov 05; 84(3):546-53. PMID: 25442933; PMCID: PMC4254615.
    Citations: 68     Fields:    Translation:HumansAnimals
  36. Hyman SE. The unconscionable gap between what we know and what we do. Sci Transl Med. 2014 Sep 10; 6(253):253cm9. PMID: 25210058.
    Citations: 4     Fields:    Translation:Humans
  37. Hyman SE. How far can mice carry autism research? Cell. 2014 Jul 03; 158(1):13-4. PMID: 24995974.
    Citations: 9     Fields:    Translation:HumansAnimals
  38. McCarroll SA, Feng G, Hyman SE. Genome-scale neurogenetics: methodology and meaning. Nat Neurosci. 2014 Jun; 17(6):756-63. PMID: 24866041.
    Citations: 44     Fields:    Translation:HumansAnimals
  39. Hyman SE. Perspective: Revealing molecular secrets. Nature. 2014 Apr 03; 508(7494):S20. PMID: 24695333.
    Citations: 4     Fields:    Translation:HumansAnimals
  40. Hyman SE. Time for new schizophrenia Rx. Science. 2014 Mar 14; 343(6176):1177. PMID: 24626901.
    Citations: 7     Fields:    Translation:Humans
  41. Hyman SE. Revitalizing psychiatric therapeutics. Neuropsychopharmacology. 2014 Jan; 39(1):220-9. PMID: 24317307.
    Citations: 40     Fields:    Translation:HumansAnimals
  42. Casey BJ, Craddock N, Cuthbert BN, Hyman SE, Lee FS, Ressler KJ. DSM-5 and RDoC: progress in psychiatry research? Nat Rev Neurosci. 2013 Nov; 14(11):810-4. PMID: 24135697.
    Citations: 98     Fields:    Translation:Humans
  43. McCarroll SA, Hyman SE. Progress in the genetics of polygenic brain disorders: significant new challenges for neurobiology. Neuron. 2013 Oct 30; 80(3):578-87. PMID: 24183011.
    Citations: 35     Fields:    Translation:HumansAnimals
  44. Hyman SE. Revolution stalled. Sci Transl Med. 2012 Oct 10; 4(155):155cm11. PMID: 23052291.
    Citations: 97     Fields:    Translation:Humans
  45. Hyman SE. Might stimulant drugs support moral agency in ADHD children? J Med Ethics. 2013 Jun; 39(6):369-70; discussion 372-3. PMID: 23001921; PMCID: PMC3664373.
    Citations:    Fields:    Translation:Humans
  46. Hyman SE. Target practice: HDAC inhibitors for schizophrenia. Nat Neurosci. 2012 Sep; 15(9):1180-1. PMID: 22929911.
    Citations: 5     Fields:    Translation:HumansAnimals
  47. Collins PY, Patel V, Joestl SS, March D, Insel TR, Daar AS, Anderson W, Dhansay MA, Phillips A, Shurin S, Walport M, Ewart W, Savill SJ, Bordin IA, Costello EJ, Durkin M, Fairburn C, Glass RI, Hall W, Huang Y, Hyman SE, Jamison K, Kaaya S, Kapur S, Kleinman A, Ogunniyi A, Otero-Ojeda A, Poo MM, Ravindranath V, Sahakian BJ, Saxena S, Singer PA, Stein DJ. Grand challenges in global mental health. Nature. 2011 Jul 06; 475(7354):27-30. PMID: 21734685.
    Citations: 588     Fields:    Translation:Humans
  48. Hyman SE. Commentary: Repairing a plane while it is flying--reflections on Rutter (2011). J Child Psychol Psychiatry. 2011 Jun; 52(6):661-2; discussion 673-5. PMID: 21434920.
    Citations:    Fields:    Translation:Humans
  49. Hyman SE. Genome-sequencing anniversary. The meaning of the Human Genome Project for neuropsychiatric disorders. Science. 2011 Feb 25; 331(6020):1026. PMID: 21350167.
    Citations: 1     Fields:    Translation:Humans
  50. Hyman SE. Cognitive enhancement: promises and perils. Neuron. 2011 Feb 24; 69(4):595-8. PMID: 21338872.
    Citations: 15     Fields:    Translation:Humans
  51. Hyman SE. Grouping diagnoses of mental disorders by their common risk factors. Am J Psychiatry. 2011 Jan; 168(1):1-3. PMID: 21205810.
    Citations: 3     Fields:    Translation:Humans
  52. Hyman SE. Emerging neurotechnologies for lie-detection: where are we now? An appraisal of Wolpe, Foster and Langleben's "Emerging neurotechnologies for lie-detection: promise and perils" five years later. Am J Bioeth. 2010 Oct; 10(10):49-50. PMID: 20945267.
    Citations: 3     Fields:    Translation:Humans
  53. Nestler EJ, Hyman SE. Animal models of neuropsychiatric disorders. Nat Neurosci. 2010 Oct; 13(10):1161-9. PMID: 20877280.
    Citations: 733     Fields:    Translation:HumansAnimals
  54. Hyman SE. A bone to pick with compulsive behavior. Cell. 2010 May 28; 141(5):752-4. PMID: 20510922.
    Citations: 3     Fields:    
  55. Hyman SE. The diagnosis of mental disorders: the problem of reification. Annu Rev Clin Psychol. 2010; 6:155-79. PMID: 17716032.
    Citations: 169     Fields:    Translation:Humans
  56. Andrews G, Goldberg DP, Krueger RF, Carpenter WT, Hyman SE, Sachdev P, Pine DS. Exploring the feasibility of a meta-structure for DSM-V and ICD-11: could it improve utility and validity? Psychol Med. 2009 Dec; 39(12):1993-2000. PMID: 19796425.
    Citations: 72     Fields:    Translation:Humans
  57. Hyman SE. How adversity gets under the skin. Nat Neurosci. 2009 Mar; 12(3):241-3. PMID: 19238182.
    Citations: 24     Fields:    Translation:HumansAnimals
  58. Hyman SE. A glimmer of light for neuropsychiatric disorders. Nature. 2008 Oct 16; 455(7215):890-3. PMID: 18923510.
    Citations: 41     Fields:    Translation:Humans
  59. Hyman SE. How might cocaine interfere with brain development? PLoS Med. 2008 Jun 10; 5(6):e130. PMID: 18547140.
    Citations:    Fields:    Translation:HumansAnimalsPHPublic Health
  60. Hyman SE, Ivleva E. Cognition in schizophrenia. Am J Psychiatry. 2008 Mar; 165(3):312. PMID: 18316429.
    Citations: 2     Fields:    Translation:Humans
  61. Paletzki RF, Myakishev MV, Polesskaya O, Orosz A, Hyman SE, Vinson C. Inhibiting activator protein-1 activity alters cocaine-induced gene expression and potentiates sensitization. Neuroscience. 2008 Apr 09; 152(4):1040-53. PMID: 18355967.
    Citations: 8     Fields:    Translation:Animals
  62. Hyman SE. How mice cope with stressful social situations. Cell. 2007 Oct 19; 131(2):232-4. PMID: 17956724.
    Citations: 6     Fields:    Translation:AnimalsCells
  63. Hyman SE. Can neuroscience be integrated into the DSM-V? Nat Rev Neurosci. 2007 Sep; 8(9):725-32. PMID: 17704814.
    Citations: 147     Fields:    Translation:Humans
  64. Hyman SE. Neuroscience: obsessed with grooming. Nature. 2007 Aug 23; 448(7156):871-2. PMID: 17713517.
    Citations: 1     Fields:    Translation:HumansAnimals
  65. Hyman SE, Insel TR. Public health contributions. Schizophr Bull. 2007 Sep; 33(5):1151-2. PMID: 17631617.
    Citations:    Fields:    Translation:HumansPHPublic Health
  66. Hyman SE. The neurobiology of addiction: implications for voluntary control of behavior. Am J Bioeth. 2007 Jan; 7(1):8-11. PMID: 17366151.
    Citations: 34     Fields:    Translation:Humans
  67. Moldin SO, Rubenstein JL, Hyman SE. Can autism speak to neuroscience? J Neurosci. 2006 Jun 28; 26(26):6893-6. PMID: 16807319; PMCID: PMC6673915.
    Citations: 10     Fields:    Translation:HumansAnimals
  68. Hyman SE. Even chromatin gets the blues. Nat Neurosci. 2006 Apr; 9(4):465-6. PMID: 16568101.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  69. Sgambato-Faure V, Xiong Y, Berke JD, Hyman SE, Strehler EE. The Homer-1 protein Ania-3 interacts with the plasma membrane calcium pump. Biochem Biophys Res Commun. 2006 May 05; 343(2):630-7. PMID: 16554037; PMCID: PMC3873836.
    Citations: 24     Fields:    Translation:AnimalsCells
  70. Hyman SE, Malenka RC, Nestler EJ. Neural mechanisms of addiction: the role of reward-related learning and memory. Annu Rev Neurosci. 2006; 29:565-98. PMID: 16776597.
    Citations: 1073     Fields:    Translation:HumansAnimalsCells
  71. Yehuda R, Hyman SE. The impact of terrorism on brain, and behavior: what we know and what we need to know. Neuropsychopharmacology. 2005 Oct; 30(10):1773-80. PMID: 16012534.
    Citations: 4     Fields:    Translation:Humans
  72. Hyman SE. Addiction: a disease of learning and memory. Am J Psychiatry. 2005 Aug; 162(8):1414-22. PMID: 16055762.
    Citations: 277     Fields:    Translation:HumansAnimals
  73. Voulalas PJ, Holtzclaw L, Wolstenholme J, Russell JT, Hyman SE. Metabotropic glutamate receptors and dopamine receptors cooperate to enhance extracellular signal-regulated kinase phosphorylation in striatal neurons. J Neurosci. 2005 Apr 13; 25(15):3763-73. PMID: 15829628; PMCID: PMC6724927.
    Citations: 24     Fields:    Translation:AnimalsCells
  74. Hyman SE. Neurotransmitters. Curr Biol. 2005 Mar 08; 15(5):R154-8. PMID: 15753022.
    Citations: 24     Fields:    Translation:HumansCells
  75. Makris N, Gasic GP, Seidman LJ, Goldstein JM, Gastfriend DR, Elman I, Albaugh MD, Hodge SM, Ziegler DA, Sheahan FS, Caviness VS, Tsuang MT, Kennedy DN, Hyman SE, Rosen BR, Breiter HC. Decreased absolute amygdala volume in cocaine addicts. Neuron. 2004 Nov 18; 44(4):729-40. PMID: 15541319.
    Citations: 67     Fields:    Translation:Humans
  76. Montague PR, Hyman SE, Cohen JD. Computational roles for dopamine in behavioural control. Nature. 2004 Oct 14; 431(7010):760-7. PMID: 15483596.
    Citations: 309     Fields:    Translation:HumansAnimals
  77. Hyman SE. Introduction: the brain's special status. Cerebrum. 2004; 6(4):9-12. PMID: 15986528.
    Citations: 2     Translation:Humans
  78. Hyman SE. Methylphenidate-induced plasticity: what should we be looking for? Biol Psychiatry. 2003 Dec 15; 54(12):1310-1. PMID: 14675793.
    Citations: 7     Fields:    Translation:HumansAnimals
  79. Hyman SE. Diagnosing disorders. Sci Am. 2003 Sep; 289(3):96-103. PMID: 12951833.
    Citations: 3     Fields:    Translation:Humans
  80. Sgambato V, Minassian R, Nairn AC, Hyman SE. Regulation of ania-6 splice variants by distinct signaling pathways in striatal neurons. J Neurochem. 2003 Jul; 86(1):153-64. PMID: 12807435.
    Citations: 8     Fields:    Translation:AnimalsCells
  81. Hyman SE, Fenton WS. Medicine. What are the right targets for psychopharmacology? Science. 2003 Jan 17; 299(5605):350-1. PMID: 12532001.
    Citations: 77     Fields:    Translation:HumansAnimals
  82. Kupfer DJ, Hyman SE, Schatzberg AF, Pincus HA, Reynolds CF. Recruiting and retaining future generations of physician scientists in mental health. Arch Gen Psychiatry. 2002 Jul; 59(7):657-60. PMID: 12090819.
    Citations: 33     Fields:    Translation:Humans
  83. Hyman SE. A new beginning for research on borderline personality disorder. Biol Psychiatry. 2002 Jun 15; 51(12):933-5. PMID: 12062876.
    Citations: 3     Fields:    Translation:Humans
  84. Hyman SE. Neuroscience, genetics, and the future of psychiatric diagnosis. Psychopathology. 2002 Mar-Jun; 35(2-3):139-44. PMID: 12145499.
    Citations: 9     Fields:    Translation:Humans
  85. Hyman SE. Managing emotional fallout. Parting remarks from America's top psychiatrist. Interview by Diane Coutu. Harv Bus Rev. 2002 Feb; 80(2):55-60, 127. PMID: 11894678.
    Citations:    Fields:    Translation:Humans
  86. Cowan WM, Kopnisky KL, Hyman SE. The human genome project and its impact on psychiatry. Annu Rev Neurosci. 2002; 25:1-50. PMID: 12052903.
    Citations: 17     Fields:    Translation:Humans
  87. Kopnisky KL, Cowan WM, Hyman SE. Levels of analysis in psychiatric research. Dev Psychopathol. 2002; 14(3):437-61. PMID: 12349868.
    Citations: 3     Fields:    Translation:HumansAnimals
  88. Lo B, Albert MS, Hyman S, Parens E, Wolpe PR, Mobley W. Ethics and the practice of brain science. Cerebrum. 2002; 4(3):64-6. PMID: 16619416.
    Citations:    Translation:Humans
  89. Hyman SE. A 28-year-old man addicted to cocaine. JAMA. 2001 Nov 28; 286(20):2586-94. PMID: 11722273.
    Citations: 4     Fields:    Translation:Humans
  90. Berke JD, Sgambato V, Zhu PP, Lavoie B, Vincent M, Krause M, Hyman SE. Dopamine and glutamate induce distinct striatal splice forms of Ania-6, an RNA polymerase II-associated cyclin. Neuron. 2001 Oct 25; 32(2):277-87. PMID: 11683997.
    Citations: 35     Fields:    Translation:AnimalsCells
  91. Hyman SE, Malenka RC. Addiction and the brain: the neurobiology of compulsion and its persistence. Nat Rev Neurosci. 2001 Oct; 2(10):695-703. PMID: 11584307.
    Citations: 351     Fields:    Translation:HumansAnimals
  92. Kosofsky BE, Hyman SE. No time for complacency: the fetal brain on drugs. J Comp Neurol. 2001 Jul 02; 435(3):259-62. PMID: 11406809.
    Citations: 5     Fields:    Translation:HumansAnimals
  93. Hyman SE. Mood disorders in children and adolescents: an NIMH perspective. Biol Psychiatry. 2001 Jun 15; 49(12):962-9. PMID: 11430838.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  94. Hyman SE. Mental health in an aging population: the NIMH perspective. Am J Geriatr Psychiatry. 2001; 9(4):330-9. PMID: 11739060.
    Citations: 6     Fields:    Translation:Humans
  95. Hyman SE. The needs for database research and for privacy collide. Am J Psychiatry. 2000 Nov; 157(11):1723-4. PMID: 11058462.
    Citations: 2     Fields:    Translation:Humans
  96. Hyman S. Mental illness: genetically complex disorders of neural circuitry and neural communication. Neuron. 2000 Nov; 28(2):321-3. PMID: 11144341.
    Citations: 9     Fields:    Translation:HumansCells
  97. Hyman SE. Genes, gene expression, and behavior. Neurobiol Dis. 2000 Oct; 7(5):528-32. PMID: 11042069.
    Citations: 1     Fields:    Translation:Humans
  98. Kogai T, Curcio F, Hyman S, Cornford EM, Brent GA, Hershman JM. Induction of follicle formation in long-term cultured normal human thyroid cells treated with thyrotropin stimulates iodide uptake but not sodium/iodide symporter messenger RNA and protein expression. J Endocrinol. 2000 Oct; 167(1):125-35. PMID: 11018760.
    Citations: 22     Fields:    Translation:Humans
  99. Hyman SE. Goals for research on bipolar disorder: the view from NIMH. Biol Psychiatry. 2000 Sep 15; 48(6):436-41. PMID: 11018216.
    Citations: 8     Fields:    Translation:HumansAnimals
  100. Hyman SE. National Institute of Mental Health goals for behavioral science. Exp Clin Psychopharmacol. 2000 Aug; 8(3):271-2. PMID: 10975615.
    Citations:    Fields:    
  101. Hyman SE, Shore D. An NIMH perspective on the use of placebos. National Institute of Mental Health. Biol Psychiatry. 2000 Apr 15; 47(8):689-91. PMID: 10773173.
    Citations: 3     Fields:    Translation:Humans
  102. Berke JD, Hyman SE. Addiction, dopamine, and the molecular mechanisms of memory. Neuron. 2000 Mar; 25(3):515-32. PMID: 10774721.
    Citations: 395     Fields:    Translation:HumansAnimals
  103. Hyman SE. The millennium of mind, brain, and behavior. Arch Gen Psychiatry. 2000 Jan; 57(1):88-9. PMID: 10632239.
    Citations: 5     Fields:    Translation:Humans
  104. Hyman SE. The NIMH perspective: next steps in schizophrenia research. Biol Psychiatry. 2000 Jan 01; 47(1):1-7. PMID: 10650443.
    Citations: 3     Fields:    Translation:Humans
  105. Hyman SE. The genetics of mental illness: implications for practice. Bull World Health Organ. 2000; 78(4):455-63. PMID: 10885164; PMCID: PMC2560734.
    Citations: 20     Fields:    Translation:Humans
  106. Shore D, Hyman SE. An NIMH commentary on the NBAC report. Biol Psychiatry. 1999 Oct 15; 46(8):1013-6. PMID: 10536736.
    Citations: 7     Fields:    Translation:Humans
  107. Shore D, Hyman SE. NIMH symptom challenge and medication discontinuation workshop. Biol Psychiatry. 1999 Oct 15; 46(8):1009-10. PMID: 10536734.
    Citations: 3     Fields:    Translation:Humans
  108. Hyman SE. Selective gene expression increases behavioral sensitivity to cocaine. Nat Neurosci. 1999 Oct; 2(10):855-6. PMID: 10491599.
    Citations: 1     Fields:    Translation:Animals
  109. Norquist G, Hyman SE. Advances in understanding and treating mental illness: implications for policy. Health Aff (Millwood). 1999 Sep-Oct; 18(5):32-47. PMID: 10495590.
    Citations: 4     Fields:    Translation:Humans
  110. Mosher LR, Goodwin FK, Thompson J, Hyman SE, Emmet W. Are psychiatrists betraying their patients? Psychol Today. 1999 Sep-Oct; 32(5):40-42, 80, 82. PMID: 11660751.
    Citations:    Translation:Humans
  111. Kobierski LA, Wong AE, Srivastava S, Borsook D, Hyman SE. Cyclic AMP-dependent activation of the proenkephalin gene requires phosphorylation of CREB at serine-133 and a Src-related kinase. J Neurochem. 1999 Jul; 73(1):129-38. PMID: 10386963.
    Citations: 10     Fields:    Translation:AnimalsCells
  112. Schwarzschild MA, Cole RL, Meyers MA, Hyman SE. Contrasting calcium dependencies of SAPK and ERK activations by glutamate in cultured striatal neurons. J Neurochem. 1999 Jun; 72(6):2248-55. PMID: 10349832.
    Citations: 13     Fields:    Translation:AnimalsCells
  113. Van Koughnet K, Smirnova O, Hyman SE, Borsook D. Proenkephalin transgene regulation in the paraventricular nucleus of the hypothalamus by lipopolysaccharide and interleukin-1beta. J Comp Neurol. 1999 Mar 08; 405(2):199-215. PMID: 10023810.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  114. Hyman SE. Protecting patients, preserving progress: ethics in mental health illness research. Acad Med. 1999 Mar; 74(3):258-9. PMID: 10099647.
    Citations: 3     Fields:    Translation:Humans
  115. Hyman SE. Introduction to the complex genetics of mental disorders. Biol Psychiatry. 1999 Mar 01; 45(5):518-21. PMID: 10088041.
    Citations: 7     Fields:    Translation:Humans
  116. Morwood DT, Nichter LS, Hyman S, Bindiger A, Miller JH, McComb JG. Omental transfer to the brain: an experimental study in hydrocephalic rabbits. Ann Plast Surg. 1999 Feb; 42(2):174-9. PMID: 10029483.
    Citations:    Fields:    Translation:Animals
  117. Hyman SE. Brain neurocircuitry of anxiety and fear: implications for clinical research and practice. Biol Psychiatry. 1998 Dec 15; 44(12):1201-3. PMID: 9861461.
    Citations: 2     Fields:    Translation:HumansAnimals
  118. Hyman SE. NIMH during the tenure of Director Steven E. Hyman, M.D. (1996-present): the now and future of NIMH. Am J Psychiatry. 1998 Sep; 155(9 Suppl):36-40. PMID: 9736863.
    Citations: 2     Fields:    Translation:Humans
  119. Genova LM, Hyman SE. 5-HT3 receptor activation is required for induction of striatal c-Fos and phosphorylation of ATF-1 by amphetamine. Synapse. 1998 Sep; 30(1):71-8. PMID: 9704883.
    Citations: 3     Fields:    Translation:AnimalsCells
  120. Fienberg AA, Hiroi N, Mermelstein PG, Song W, Snyder GL, Nishi A, Cheramy A, O'Callaghan JP, Miller DB, Cole DG, Corbett R, Haile CN, Cooper DC, Onn SP, Grace AA, Ouimet CC, White FJ, Hyman SE, Surmeier DJ, Girault J, Nestler EJ, Greengard P. DARPP-32: regulator of the efficacy of dopaminergic neurotransmission. Science. 1998 Aug 07; 281(5378):838-42. PMID: 9694658.
    Citations: 140     Fields:    Translation:AnimalsCells
  121. Berke JD, Paletzki RF, Aronson GJ, Hyman SE, Gerfen CR. A complex program of striatal gene expression induced by dopaminergic stimulation. J Neurosci. 1998 Jul 15; 18(14):5301-10. PMID: 9651213; PMCID: PMC6793476.
    Citations: 87     Fields:    Translation:AnimalsCells
  122. Gollub RL, Breiter HC, Kantor H, Kennedy D, Gastfriend D, Mathew RT, Makris N, Guimaraes A, Riorden J, Campbell T, Foley M, Hyman SE, Rosen B, Weisskoff R. Cocaine decreases cortical cerebral blood flow but does not obscure regional activation in functional magnetic resonance imaging in human subjects. J Cereb Blood Flow Metab. 1998 Jul; 18(7):724-34. PMID: 9663502.
    Citations: 31     Fields:    Translation:Humans
  123. Hyman SE, Zuckerman B. Drug interactions in cocaine abuse: methodologic concerns in human and animal studies. Ann N Y Acad Sci. 1998 Jun 21; 846:69-75. PMID: 9668398.
    Citations:    Fields:    Translation:HumansAnimals
  124. Hyman SE. A new image for fear and emotion. Nature. 1998 Jun 04; 393(6684):417-8. PMID: 9623995.
    Citations: 3     Fields:    Translation:HumansAnimals
  125. Cornford EM, Hyman S, Cornford ME, Damian RT. Glut1 glucose transporter in the primate choroid plexus endothelium. J Neuropathol Exp Neurol. 1998 May; 57(5):404-14. PMID: 9596411.
    Citations: 4     Fields:    Translation:HumansAnimals
  126. Hyman SE. The K-05 award controversy. Arch Gen Psychiatry. 1998 Jan; 55(1):21-2. PMID: 9435755.
    Citations:    Fields:    Translation:Humans
  127. Cornford EM, Hyman S, Cornford ME, Landaw EM, Delgado-Escueta AV. Interictal seizure resections show two configurations of endothelial Glut1 glucose transporter in the human blood-brain barrier. J Cereb Blood Flow Metab. 1998 Jan; 18(1):26-42. PMID: 9428303.
    Citations: 27     Fields:    Translation:Humans
  128. Glick TH, Armstrong EG, Waterman MA, Hundert EM, Hyman SE. An integrated preclerkship curriculum in neuroscience, psychiatry, and neurology. Acad Psychiatry. 1997 Dec; 21(4):212-8. PMID: 24435648.
    Citations:    Fields:    
  129. Breiter HC, Gollub RL, Weisskoff RM, Kennedy DN, Makris N, Berke JD, Goodman JM, Kantor HL, Gastfriend DR, Riorden JP, Mathew RT, Rosen BR, Hyman SE. Acute effects of cocaine on human brain activity and emotion. Neuron. 1997 Sep; 19(3):591-611. PMID: 9331351.
    Citations: 354     Fields:    Translation:HumansCTClinical Trials
  130. Schwarzschild MA, Cole RL, Hyman SE. Glutamate, but not dopamine, stimulates stress-activated protein kinase and AP-1-mediated transcription in striatal neurons. J Neurosci. 1997 May 15; 17(10):3455-66. PMID: 9133371; PMCID: PMC6573695.
    Citations: 29     Fields:    Translation:AnimalsCells
  131. Glick TH, Armstrong EG, Hyman SE, Hundert EM, Furshpan EJ. Neurologic education for the future: a decade of curricular reform at Harvard Medical School. Eur J Neurol. 1997 Mar; 4(2):102-6. PMID: 24283899.
    Citations:    Fields:    
  132. Genova L, Berke J, Hyman SE. Molecular adaptations to psychostimulants in striatal neurons: toward a pathophysiology of addiction. Neurobiol Dis. 1997; 4(3-4):239-46. PMID: 9361300.
    Citations:    Fields:    Translation:HumansAnimalsCells
  133. Berhow MT, Hiroi N, Kobierski LA, Hyman SE, Nestler EJ. Influence of cocaine on the JAK-STAT pathway in the mesolimbic dopamine system. J Neurosci. 1996 Dec 15; 16(24):8019-26. PMID: 8987828; PMCID: PMC6579209.
    Citations: 12     Fields:    Translation:Animals
  134. Breiter HC, Etcoff NL, Whalen PJ, Kennedy WA, Rauch SL, Buckner RL, Strauss MM, Hyman SE, Rosen BR. Response and habituation of the human amygdala during visual processing of facial expression. Neuron. 1996 Nov; 17(5):875-87. PMID: 8938120.
    Citations: 425     Fields:    Translation:Humans
  135. Hyman SE. Shaking out the cause of addiction. Science. 1996 Aug 02; 273(5275):611-2. PMID: 8701316.
    Citations: 4     Fields:    Translation:AnimalsCells
  136. Konradi C, Leveque JC, Hyman SE. Amphetamine and dopamine-induced immediate early gene expression in striatal neurons depends on postsynaptic NMDA receptors and calcium. J Neurosci. 1996 Jul 01; 16(13):4231-9. PMID: 8753884; PMCID: PMC4203342.
    Citations: 81     Fields:    Translation:AnimalsCells
  137. Hyman SE. Addiction to cocaine and amphetamine. Neuron. 1996 May; 16(5):901-4. PMID: 8630246.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  138. Hyman SE, Nestler EJ. Initiation and adaptation: a paradigm for understanding psychotropic drug action. Am J Psychiatry. 1996 Feb; 153(2):151-62. PMID: 8561194.
    Citations: 83     Fields:    Translation:HumansAnimalsCells
  139. Hyman SE, Borsook D. Mechanisms regulating proenkephalin gene expression: contributions of transgenic models. NIDA Res Monogr. 1996; 161:59-71. PMID: 8784844.
    Citations: 1     Fields:    Translation:Animals
  140. Hyman SE. A man with alcoholism and HIV infection. JAMA. 1995 Sep 13; 274(10):837-43. PMID: 7650809.
    Citations: 1     Fields:    Translation:Humans
  141. Hyman SE. Current treatment for alcohol withdrawal. J Gen Intern Med. 1995 Sep; 10(9):523-4. PMID: 8523158.
    Citations: 1     Fields:    Translation:Humans
  142. Borsook D, Hyman SE. Proenkephalin gene regulation in the neuroendocrine hypothalamus: a model of gene regulation in the CNS. Am J Physiol. 1995 Sep; 269(3 Pt 1):E393-408. PMID: 7573416.
    Citations: 9     Fields:    Translation:HumansAnimals
  143. Konradi C, Cole RL, Green D, Senatus P, Leveque JC, Pollack AE, Grossbard SJ, Hyman SE. Analysis of the proenkephalin second messenger-inducible enhancer in rat striatal cultures. J Neurochem. 1995 Sep; 65(3):1007-15. PMID: 7643080.
    Citations: 11     Fields:    Translation:AnimalsCells
  144. Gollub RL, Hyman SE. G proteins and second messengers in psychiatry. Harv Rev Psychiatry. 1995 May-Jun; 3(1):41-4. PMID: 9410573.
    Citations:    Fields:    Translation:HumansCells
  145. Naidu S, Hyman S, Harris EL, Narayanan V, Johns D, Castora F. Rett syndrome studies of natural history and search for a genetic marker. Neuropediatrics. 1995 Apr; 26(2):63-6. PMID: 7566454.
    Citations: 5     Fields:    Translation:HumansCells
  146. Hyman SE, Cole RL, Konradi C, Kosofsky BE. Dopamine regulation of transcription factor-target interactions in rat striatum. Chem Senses. 1995 Apr; 20(2):257-60. PMID: 7583020.
    Citations: 11     Fields:    Translation:Animals
  147. Cole RL, Konradi C, Douglass J, Hyman SE. Neuronal adaptation to amphetamine and dopamine: molecular mechanisms of prodynorphin gene regulation in rat striatum. Neuron. 1995 Apr; 14(4):813-23. PMID: 7718243.
    Citations: 93     Fields:    Translation:AnimalsCells
  148. Kosofsky BE, Genova LM, Hyman SE. Postnatal age defines specificity of immediate early gene induction by cocaine in developing rat brain. J Comp Neurol. 1995 Jan 02; 351(1):27-40. PMID: 7896938.
    Citations: 7     Fields:    Translation:AnimalsCells
  149. Kosofsky BE, Genova LM, Hyman SE. Substance P phenotype defines specificity of c-fos induction by cocaine in developing rat striatum. J Comp Neurol. 1995 Jan 02; 351(1):41-50. PMID: 7534774.
    Citations: 7     Fields:    Translation:Animals
  150. Borsook D, Falkowski O, Rosen H, Comb M, Hyman SE. Opioids modulate stress-induced proenkephalin gene expression in the hypothalamus of transgenic mice: a model of endogenous opioid gene regulation by exogenous opioids. J Neurosci. 1994 Dec; 14(12):7261-71. PMID: 7996174; PMCID: PMC6576895.
    Citations: 4     Fields:    Translation:Animals
  151. Symes A, Lewis S, Corpus L, Rajan P, Hyman SE, Fink JS. STAT proteins participate in the regulation of the vasoactive intestinal peptide gene by the ciliary neurotrophic factor family of cytokines. Mol Endocrinol. 1994 Dec; 8(12):1750-63. PMID: 7708062.
    Citations: 20     Fields:    Translation:HumansCells
  152. Cornford EM, Hyman S, Landaw EM. Developmental modulation of blood-brain-barrier glucose transport in the rabbit. Brain Res. 1994 Nov 07; 663(1):7-18. PMID: 7850472.
    Citations: 5     Fields:    Translation:Animals
  153. Hyman SE, Gollub RL. More serotonin: not as simple as it seems. Harv Rev Psychiatry. 1994 Nov-Dec; 2(4):222-4. PMID: 9384905.
    Citations: 1     Fields:    Translation:Humans
  154. Schwarzschild MA, Dauer WT, Lewis SE, Hamill LK, Fink JS, Hyman SE. Leukemia inhibitory factor and ciliary neurotrophic factor increase activated Ras in a neuroblastoma cell line and in sympathetic neuron cultures. J Neurochem. 1994 Oct; 63(4):1246-54. PMID: 7523587.
    Citations: 1     Fields:    Translation:AnimalsCells
  155. Cole DG, Kobierski LA, Konradi C, Hyman SE. 6-Hydroxydopamine lesions of rat substantia nigra up-regulate dopamine-induced phosphorylation of the cAMP-response element-binding protein in striatal neurons. Proc Natl Acad Sci U S A. 1994 Sep 27; 91(20):9631-5. PMID: 7937819; PMCID: PMC44867.
    Citations: 12     Fields:    Translation:AnimalsCells
  156. Konradi C, Cole RL, Heckers S, Hyman SE. Amphetamine regulates gene expression in rat striatum via transcription factor CREB. J Neurosci. 1994 Sep; 14(9):5623-34. PMID: 8083758; PMCID: PMC6577107.
    Citations: 92     Fields:    Translation:AnimalsCells
  157. Lewis SE, Rao MS, Symes AJ, Dauer WT, Fink JS, Landis SC, Hyman SE. Coordinate regulation of choline acetyltransferase, tyrosine hydroxylase, and neuropeptide mRNAs by ciliary neurotrophic factor and leukemia inhibitory factor in cultured sympathetic neurons. J Neurochem. 1994 Aug; 63(2):429-38. PMID: 7518494.
    Citations: 21     Fields:    Translation:AnimalsCells
  158. Hyman SE. Why does the brain prefer opium to broccoli? Harv Rev Psychiatry. 1994 May-Jun; 2(1):43-6. PMID: 9384879.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  159. Borsook D, Konradi C, Falkowski O, Comb M, Hyman SE. Molecular mechanisms of stress-induced proenkephalin gene regulation: CREB interacts with the proenkephalin gene in the mouse hypothalamus and is phosphorylated in response to hyperosmolar stress. Mol Endocrinol. 1994 Feb; 8(2):240-8. PMID: 8170480; PMCID: PMC4205567.
    Citations: 12     Fields:    Translation:AnimalsCells
  160. Hyman SE, Konradi C, Kobierski L, Cole R, Senatus P, Green D. Pharmacologic regulation of striatal proenkephalin gene expression via transcription factor CREB. Prog Clin Biol Res. 1994; 390:155-71. PMID: 7724644.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  161. Cornford EM, Hyman S, Swartz BE. The human brain GLUT1 glucose transporter: ultrastructural localization to the blood-brain barrier endothelia. J Cereb Blood Flow Metab. 1994 Jan; 14(1):106-12. PMID: 8263045.
    Citations: 35     Fields:    Translation:HumansCells
  162. Borsook D, Falkowski O, Burstein R, Strassman A, Konradi C, Dauber A, Comb M, Hyman SE. Stress-induced regulation of a human proenkephalin-beta-galactosidase fusion gene in the hypothalamus of transgenic mice. Mol Endocrinol. 1994 Jan; 8(1):116-25. PMID: 8152426.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  163. Hyman SE. Another one bites the dust: an infectious origin for peptic ulcers. Harv Rev Psychiatry. 1994 Jan-Feb; 1(5):294-5. PMID: 9384861.
    Citations: 3     Fields:    Translation:HumansCells
  164. Cornford EM, Hyman S, Pardridge WM. An electron microscopic immunogold analysis of developmental up-regulation of the blood-brain barrier GLUT1 glucose transporter. J Cereb Blood Flow Metab. 1993 Sep; 13(5):841-54. PMID: 8360290.
    Citations: 12     Fields:    Translation:AnimalsCells
  165. Hyman SE. Molecular and cell biology of addiction. Curr Opin Neurol Neurosurg. 1993 Aug; 6(4):609-13. PMID: 8400475.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  166. Konradi C, Kobierski LA, Nguyen TV, Heckers S, Hyman SE. The cAMP-response-element-binding protein interacts, but Fos protein does not interact, with the proenkephalin enhancer in rat striatum. Proc Natl Acad Sci U S A. 1993 Aug 01; 90(15):7005-9. PMID: 8346209; PMCID: PMC47064.
    Citations: 32     Fields:    Translation:AnimalsCells
  167. Hyman SE. New insights into how antipsychotic drugs might work. Harv Rev Psychiatry. 1993 May-Jun; 1(1):68-9. PMID: 9384831.
    Citations: 1     Fields:    Translation:Humans
  168. Tang G, Hyman S, Schneider JH, Giannotta SL. Application of photodynamic therapy to the treatment of atherosclerotic plaques. Neurosurgery. 1993 Mar; 32(3):438-43; discussion 443. PMID: 8455769.
    Citations: 7     Fields:    Translation:Animals
  169. Symes AJ, Rao MS, Lewis SE, Landis SC, Hyman SE, Fink JS. Ciliary neurotrophic factor coordinately activates transcription of neuropeptide genes in a neuroblastoma cell line. Proc Natl Acad Sci U S A. 1993 Jan 15; 90(2):572-6. PMID: 8093644; PMCID: PMC45705.
    Citations: 10     Fields:    Translation:Cells
  170. Kosofsky BE, Hyman SE. The ontogeny of immediate early gene response to cocaine: a molecular analysis of the effects of cocaine on developing rat brain. NIDA Res Monogr. 1993; 125:161-71. PMID: 8341363.
    Citations: 1     Fields:    Translation:HumansAnimals
  171. Hyman SE, Kosofsky BE, Nguyen TV, Cohen BM, Comb MJ. Everything activates c-fos--how can it matter? NIDA Res Monogr. 1993; 125:25-38. PMID: 8341366.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  172. Borsook D, Rosen H, Collard M, Dressler H, Herrup K, Comb MJ, Hyman SE. Expression and regulation of a proenkephalin beta-galactosidase fusion gene in the reproductive system of transgenic mice. Mol Endocrinol. 1992 Sep; 6(9):1502-12. PMID: 1435791.
    Citations: 2     Fields:    Translation:Animals
  173. Hope B, Kosofsky B, Hyman SE, Nestler EJ. Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine. Proc Natl Acad Sci U S A. 1992 Jul 01; 89(13):5764-8. PMID: 1631058; PMCID: PMC402098.
    Citations: 141     Fields:    Translation:Animals
  174. Nguyen TV, Kosofsky BE, Birnbaum R, Cohen BM, Hyman SE. Differential expression of c-fos and zif268 in rat striatum after haloperidol, clozapine, and amphetamine. Proc Natl Acad Sci U S A. 1992 May 15; 89(10):4270-4. PMID: 1374894; PMCID: PMC49063.
    Citations: 57     Fields:    Translation:AnimalsCells
  175. Comb MJ, Kobierski L, Chu HM, Tan Y, Borsook D, Herrup K, Hyman SE. Regulation of opioid gene expression: a model to understand neural plasticity. NIDA Res Monogr. 1992; 126:98-112. PMID: 1491720.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  176. Zlokovic BV, Hyman S, McComb JG, Tang G, Rezai AR, Weiss MH. Vasopressin uptake by hypothalamopituitary axis and pineal gland in guinea pigs. Am J Physiol. 1991 Apr; 260(4 Pt 1):E633-40. PMID: 1902062.
    Citations: 1     Fields:    Translation:Animals
  177. Zlokovic BV, Segal MB, McComb JG, Hyman S, Weiss MH, Davson H. Kinetics of circulating vasopressin uptake by choroid plexus. Am J Physiol. 1991 Feb; 260(2 Pt 2):F216-24. PMID: 1899978.
    Citations: 4     Fields:    Translation:Animals
  178. Comb M, Hyman SE, Kobierski L, Chu HM, Van Nguyen T. Mechanisms underlying synaptic regulation of proenkephalin transcription. NIDA Res Monogr. 1991; 111:149-70. PMID: 1663581.
    Citations: 1     Fields:    Translation:HumansCells
  179. Jenike MA, Hyman S, Baer L, Holland A, Minichiello WE, Buttolph L, Summergrad P, Seymour R, Ricciardi J. A controlled trial of fluvoxamine in obsessive-compulsive disorder: implications for a serotonergic theory. Am J Psychiatry. 1990 Sep; 147(9):1209-15. PMID: 2143637.
    Citations: 19     Fields:    Translation:HumansCTClinical Trials
  180. Van Nguyen T, Kobierski L, Comb M, Hyman SE. The effect of depolarization on expression of the human proenkephalin gene is synergistic with cAMP and dependent upon a cAMP-inducible enhancer. J Neurosci. 1990 Aug; 10(8):2825-33. PMID: 2167356; PMCID: PMC6570260.
    Citations: 26     Fields:    Translation:HumansCells
  181. Ross ME, Evinger MJ, Hyman SE, Carroll JM, Mucke L, Comb M, Reis DJ, Joh TH, Goodman HM. Identification of a functional glucocorticoid response element in the phenylethanolamine N-methyltransferase promoter using fusion genes introduced into chromaffin cells in primary culture. J Neurosci. 1990 Feb; 10(2):520-30. PMID: 2303857; PMCID: PMC6570158.
    Citations: 26     Fields:    Translation:AnimalsCells
  182. Cohen BM, Nguyen TV, Hyman SE. Cocaine-induced changes in gene expression in rat brain. NIDA Res Monogr. 1990; 105:175-81. PMID: 1831539.
    Citations: 3     Fields:    Translation:AnimalsCells
  183. Erlich SS, McComb JG, Hyman S, Weiss MH. Ultrastructure of the orbital pathway for cerebrospinal fluid drainage in rabbits. J Neurosurg. 1989 Jun; 70(6):926-31. PMID: 2715821.
    Citations: 13     Fields:    Translation:Animals
  184. Breeze RE, McComb JG, Hyman S, Gilles FH. CSF production in acute ventriculitis. J Neurosurg. 1989 Apr; 70(4):619-22. PMID: 2647919.
    Citations: 7     Fields:    Translation:Animals
  185. Hyman SE, Comb M, Pearlberg J, Goodman HM. An AP-2 element acts synergistically with the cyclic AMP- and phorbol ester-inducible enhancer of the human proenkephalin gene. Mol Cell Biol. 1989 Jan; 9(1):321-4. PMID: 2538722.
    Citations: 35     Fields:    Translation:HumansCells
  186. Comb M, Mermod N, Hyman SE, Pearlberg J, Ross ME, Goodman HM. Proteins bound at adjacent DNA elements act synergistically to regulate human proenkephalin cAMP inducible transcription. EMBO J. 1988 Dec 01; 7(12):3793-805. PMID: 2850173; PMCID: PMC454956.
    Citations: 73     Fields:    Translation:HumansCells