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Last Name

profileBenjamin Adam Olenchock, M.D., Ph.D.

TitleInstructor in Medicine
InstitutionBrigham and Women's Hospital
AddressBrigham and Womens Hospital
Medicine - PBB-B
75 Francis St
Boston MA 02115
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
K08HL119355     (OLENCHOCK, BENJAMIN A)Aug 15, 2013 - Jul 31, 2018
Regulation of cellular metabolism by EglN dioxygenases
Role: Principal Investigator

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Olenchock BA, Rathmell JC, Vander Heiden MG. Biochemical Underpinnings of Immune Cell Metabolic Phenotypes. Immunity. 2017 May 16; 46(5):703-713. PMID: 28514672.
    View in: PubMed
  2. Herajärvi J, Anttila T, Dimova EY, Laukka T, Myllymäki M, Haapanen H, Olenchock BA, Tuominen H, Puistola U, Karihtala P, Kiviluoma K, Koivunen P, Anttila V, Juvonen T. Exploring effects of remote ischemic preconditioning in a pig model of hypothermic circulatory arrest. Scand Cardiovasc J. 2017 Aug; 51(4):233-241. PMID: 28434264.
    View in: PubMed
  3. Johnson DB, Balko JM, Compton ML, Chalkias S, Gorham J, Xu Y, Hicks M, Puzanov I, Alexander MR, Bloomer TL, Becker JR, Slosky DA, Phillips EJ, Pilkinton MA, Craig-Owens L, Kola N, Plautz G, Reshef DS, Deutsch JS, Deering RP, Olenchock BA, Lichtman AH, Roden DM, Seidman CE, Koralnik IJ, Seidman JG, Hoffman RD, Taube JM, Diaz LA, Anders RA, Sosman JA, Moslehi JJ. Fulminant Myocarditis with Combination Immune Checkpoint Blockade. N Engl J Med. 2016 Nov 03; 375(18):1749-1755. PMID: 27806233.
    View in: PubMed
  4. Katz JN, Minder M, Olenchock B, Price S, Goldfarb M, Washam JB, Barnett CF, Newby LK, van Diepen S. The Genesis, Maturation, and Future of Critical Care Cardiology. J Am Coll Cardiol. 2016 Jul 05; 68(1):67-79. PMID: 27364053.
    View in: PubMed
  5. Briggs KJ, Koivunen P, Cao S, Backus KM, Olenchock BA, Patel H, Zhang Q, Signoretti S, Gerfen GJ, Richardson AL, Witkiewicz AK, Cravatt BF, Clardy J, Kaelin WG. Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine. Cell. 2016 Jun 30; 166(1):126-39. PMID: 27368101; PMCID: PMC4930557 [Available on 06/30/17].
  6. Olenchock BA, Moslehi J, Baik AH, Davidson SM, Williams J, Gibson WJ, Chakraborty AA, Pierce KA, Miller CM, Hanse EA, Kelekar A, Sullivan LB, Wagers AJ, Clish CB, Vander Heiden MG, Kaelin WG. EGLN1 Inhibition and Rerouting of a-Ketoglutarate Suffice for Remote Ischemic Protection. Cell. 2016 Apr 07; 165(2):497. PMID: 27058668.
    View in: PubMed
  7. Olenchock BA, Moslehi J, Baik AH, Davidson SM, Williams J, Gibson WJ, Chakraborty AA, Pierce KA, Miller CM, Hanse EA, Kelekar A, Sullivan LB, Wagers AJ, Clish CB, Vander Heiden MG, Kaelin WG. EGLN1 Inhibition and Rerouting of a-Ketoglutarate Suffice for Remote Ischemic Protection. Cell. 2016 Feb 25; 164(5):884-95. PMID: 26919427; PMCID: PMC4819986 [Available on 02/25/17].
  8. Davidson SM, Papagiannakopoulos T, Olenchock BA, Heyman JE, Keibler MA, Luengo A, Bauer MR, Jha AK, O'Brien JP, Pierce KA, Gui DY, Sullivan LB, Wasylenko TM, Subbaraj L, Chin CR, Stephanopolous G, Mott BT, Jacks T, Clish CB, Vander Heiden MG. Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer. Cell Metab. 2016 Mar 08; 23(3):517-28. PMID: 26853747; PMCID: PMC4785096 [Available on 03/08/17].
  9. Berg DD, Sukul D, O'Brien M, Scirica BM, Sobieszczyk PS, Olenchock BA, Bohula EA, Morrow DA. Outcomes in patients undergoing percutaneous ventricular assist device implantation for cardiogenic shock. Eur Heart J Acute Cardiovasc Care. 2016 Apr; 5(2):108-16. PMID: 25931573; PMCID: PMC4627853 [Available on 04/01/17].
  10. Lorenzo FR, Huff C, Myllymäki M, Olenchock B, Swierczek S, Tashi T, Gordeuk V, Wuren T, Ri-Li G, McClain DA, Khan TM, Koul PA, Guchhait P, Salama ME, Xing J, Semenza GL, Liberzon E, Wilson A, Simonson TS, Jorde LB, Kaelin WG, Koivunen P, Prchal JT. A genetic mechanism for Tibetan high-altitude adaptation. Nat Genet. 2014 Sep; 46(9):951-6. PMID: 25129147; PMCID: PMC4473257.
  11. Edrich T, Seethala RR, Olenchock BA, Mizuguchi AK, Rivero JM, Beutler SS, Fox JA, Liu X, Frendl G. Providing initial transthoracic echocardiography training for anesthesiologists: simulator training is not inferior to live training. J Cardiothorac Vasc Anesth. 2014 Feb; 28(1):49-53. PMID: 24183827.
    View in: PubMed
  12. Olenchock BA, Vander Heiden MG. Pyruvate as a pivot point for oncogene-induced senescence. Cell. 2013 Jun 20; 153(7):1429-30. PMID: 23791173; PMCID: PMC3753778.
  13. O'Malley RG, Olenchock B, Bohula-May E, Barnett C, Fintel DJ, Granger CB, Katz JN, Kontos MC, Kuvin JT, Murphy SA, Parrillo JE, Morrow DA. Organization and staffing practices in US cardiac intensive care units: a survey on behalf of the American Heart Association Writing Group on the Evolution of Critical Care Cardiology. Eur Heart J Acute Cardiovasc Care. 2013 Mar; 2(1):3-8. PMID: 24062928; PMCID: PMC3760580.
  14. Fendt SM, Bell EL, Keibler MA, Olenchock BA, Mayers JR, Wasylenko TM, Vokes NI, Guarente L, Vander Heiden MG, Stephanopoulos G. Reductive glutamine metabolism is a function of the a-ketoglutarate to citrate ratio in cells. Nat Commun. 2013; 4:2236. PMID: 23900562; PMCID: PMC3934748.
  15. Abtahian F, Olenchock B, Ou FS, Kontos MC, Saucedo JF, Scirica BM, Desai N, Peterson E, Roe M, Cannon CP, Wiviott SD. Effect of prior stroke on the use of evidence-based therapies and in-hospital outcomes in patients with myocardial infarction (from the NCDR ACTION GWTG registry). Am J Cardiol. 2011 May 15; 107(10):1441-6. PMID: 21420059; PMCID: PMC3743416.
  16. Russo LA, Peano BJ, Trivedi SP, Cavalcanto TD, Olenchock BA, Caruso JA, Smolock AR, Vishnevsky O, Gardner RM. Regulated expression of matrix metalloproteinases, inflammatory mediators, and endometrial matrix remodeling by 17beta-estradiol in the immature rat uterus. Reprod Biol Endocrinol. 2009 Nov 04; 7:124. PMID: 19889233; PMCID: PMC2776020.
  17. Olenchock BA, Fonarow GG, Pan W, Hernandez A, Cannon CP. Current use of beta blockers in patients with reactive airway disease who are hospitalized with acute coronary syndromes. Am J Cardiol. 2009 Feb 01; 103(3):295-300. PMID: 19166678.
    View in: PubMed
  18. Olenchock BA, Wiviott SD, Murphy SA, Cannon CP, Rifai N, Braunwald E, Morrow DA. Lack of association between soluble CD40L and risk in a large cohort of patients with acute coronary syndrome in OPUS TIMI-16. J Thromb Thrombolysis. 2008 Oct; 26(2):79-84. PMID: 17917707.
    View in: PubMed
  19. Zhong XP, Olenchock BA, Koretzky GA. The role of diacylglycerol kinases in T cell anergy. Ernst Schering Found Symp Proc. 2007; (3):139-49. PMID: 18510102.
    View in: PubMed
  20. Olenchock BA, Guo R, Carpenter JH, Jordan M, Topham MK, Koretzky GA, Zhong XP. Disruption of diacylglycerol metabolism impairs the induction of T cell anergy. Nat Immunol. 2006 Nov; 7(11):1174-81. PMID: 17028587.
    View in: PubMed
  21. Olenchock BA, Guo R, Silverman MA, Wu JN, Carpenter JH, Koretzky GA, Zhong XP. Impaired degranulation but enhanced cytokine production after Fc epsilonRI stimulation of diacylglycerol kinase zeta-deficient mast cells. J Exp Med. 2006 Jun 12; 203(6):1471-80. PMID: 16717114; PMCID: PMC2118304.
  22. Vakoc CR, Mandat SA, Olenchock BA, Blobel GA. Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin. Mol Cell. 2005 Aug 05; 19(3):381-91. PMID: 16061184.
    View in: PubMed
  23. Zhong XP, Hainey EA, Olenchock BA, Jordan MS, Maltzman JS, Nichols KE, Shen H, Koretzky GA. Enhanced T cell responses due to diacylglycerol kinase zeta deficiency. Nat Immunol. 2003 Sep; 4(9):882-90. PMID: 12883552.
    View in: PubMed
  24. Koretzky GA, Abtahian F, Derimanov GS, Dmowski SA, Guerriero A, Jordan MS, Maltzman JS, Olenchock BA, Singer AL, Wu JN, Zhong XP. Regulation of hematopoietic cell development and activation by adapter proteins. Immunol Res. 2003; 27(2-3):357-66. PMID: 12857981.
    View in: PubMed
  25. Zhong XP, Hainey EA, Olenchock BA, Zhao H, Topham MK, Koretzky GA. Regulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase zeta. J Biol Chem. 2002 Aug 23; 277(34):31089-98. PMID: 12070163.
    View in: PubMed
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