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Anne Shee CC Lee, M.D.

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Overview
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Dr. Lee's research focuses on global perinatal epidemiology and the design and evaluation of interventions to reduce the major causes of maternal and neonatal morbidity and mortality. She directs the Brigham and Women's Global Advancement of Infants and Mothers (AIM) lab.

Current research projects include the:
* Evaluation of the impact of a package of antenatal care interventions to optimize maternal nutrition and infection control on maternal and newborn health outcomes in Ethiopia (the "ENAT" study);
* Evaluation of the impact of screening-and-treatment programs for maternal genitourinary tract infections on perinatal outcomes Sylhet Bangladesh;
* Development and validation of methods of estimating gestational age before and after birth;
* Development and validation of a novel tool, the Bili-ruler, to improve jaundice screening in low income settings;
* Investigation of the vaginal microbiome and inflammatory responses associated with bacterial vaginosis infection and preterm birth;
* Estimation of the global burden of disease of fetal growth restriction and preterm birth and their risk factors
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Research
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R01HD107475 (LEE, ANNE SHEE CC) Jul 1, 2022 - Jun 30, 2027
    NIH
    Effect of iodized salt in pregnancy and lactation on infant neurodevelopment in rural Ethiopia
    Role: Principal Investigator
  2. R01HD106106 (LEE, ANNE SHEE CC) Jul 1, 2022 - Mar 31, 2027
    NIH
    Nutrition and Inflammation in Pregnancy: Impacts on Early Human Brain Development
    Role: Principal Investigator
  3. OPP1184363 (Anne CC Lee) Nov 27, 2017 - Oct 30, 2023
    Bill and Melinda Gates Foundation
    Addressing maternal infection combined with nutrition support to improve birthweight and linear growth in Africa
    Role Description: The Enhancing Nutrition and Antenatal infection Treatment (ENAT) study is a cluster randomized trial that will determine the impact of packages of antenatal care interventions to enhance maternal nutritional status and manage maternal pregnancy infections on newborn size at birth.
    Role: Principal Investigator
  4. K23HD091390 (LEE, ANNE SHEE CC) Aug 21, 2017 - Jun 30, 2022
    NIH
    The Roles of Perinatal Nutrition, Infection and Inflammation in the Neurodevelopment of Bangladeshi Infants
    Role Description: The goals of this study are to: 1) determine the associations of pregnancy undernutrition and infections on fetal inflammatory responses, and 2) examine the associations of fetal inflammation and neurodevelopmental outcomes at 2 years.
    Role: Principal Investigator
  5. R01HD066156 (BAQUI, ABDULLAH HEL) Aug 10, 2010 - May 31, 2015
    NIH
    Maternal genitourinary infections and adverse perinatal outcomes
    Role Description: The specific aim of this study was to determine the impact of community-based screening and treatment of abnormal vaginal flora and urinary tract infections in early pregnancy on adverse pregnancy outcomes in Sylhet district, Bangladesh.
    Role: Co-Investigator

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© 2025 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.