Harvard Catalyst Profiles

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Calum Archibald MacRae, Ph.D., M.D.


Integration of in Vitro and in Vivo Models of Arrhythmogenic Cardiomyopathy to Define Pathogenic Mechanisms and Identify Small Molecule Therapies
Summer, 06/01/18 - 08/31/18
Development of a new zebrafish model for studying cell-autonomous connexin mutants linked to atrial fibrillation
Summer, 06/05/15 - 08/15/15

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U54NS112107 (MACRAE, CALUM A.) Aug 1, 2019 - May 31, 2024
    Advancing novel cyanide countermeasures
    Role: Principal Investigator
  2. R01HG009174 (MURPHY, SHAWN N) Sep 28, 2016 - Feb 28, 2021
    Developing i2b2 into a Health Innovation Platform for Clinical Decision Support in the Genomics Era
    Role: Co-Principal Investigator
  3. R24OD017870 (GOESSLING, WOLFRAM) May 1, 2014 - Jul 31, 2022
    A Community Zebrafish Resource for Modeling GWAS Biology
    Role: Co-Principal Investigator
  4. U54NS079201 (MACRAE, CALUM A.) Sep 30, 2012 - Aug 31, 2018
    A Discovery and Development Pipeline for Cyanide Countermeasures
    Role: Principal Investigator
  5. R01HL109264 (MACRAE, CALUM A.) Apr 9, 2012 - Feb 29, 2016
    Development of a High-throughput Integrated In Vivo Heart Failure Assay
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Marchal GA, Jouni M, Chiang DY, Pérez-Hernández Duran M, Podliesna S, Yu N, Casini S, Potet F, Veerman CC, Klerk M, Lodder EM, Mengarelli I, Guan K, Vanoye CG, Rothenberg E, Charpentier F, Redon R, George A, Verkerk AO, Bezzina CR, MacRae CA, Burridge P, Delmar M, Galjart NJ, Portero V, Remme CA. Targeting the Microtubule EB1-CLASP2 Complex Modulates NaV1.5 at Intercalated Discs. Circ Res. 2021 Jun 07. PMID: 34092082.
    Citations:    Fields:    
  2. Goto S, Mahara K, Beussink-Nelson L, Ikura H, Katsumata Y, Endo J, Gaggin HK, Shah SJ, Itabashi Y, MacRae CA, Deo RC. Artificial intelligence-enabled fully automated detection of cardiac amyloidosis using electrocardiograms and echocardiograms. Nat Commun. 2021 05 11; 12(1):2726. PMID: 33976142.
    Citations:    Fields:    
  3. Figtree GA, Broadfoot K, Casadei B, Califf R, Crea F, Drummond GR, Freedman JE, Guzik TJ, Harrison D, Hausenloy DJ, Hill JA, Januzzi JL, Kingwell BA, Lam CSP, MacRae CA, Misselwitz F, Miura T, Ritchie RH, Tomaszewski M, Wu JC, Xiao J, Zannad F. A Call to Action for New Global Approaches to Cardiovascular Disease Drug Solutions. Circulation. 2021 Apr 20; CIR0000000000000981. PMID: 33876947.
    Citations:    Fields:    
  4. Figtree GA, Broadfoot K, Casadei B, Califf R, Crea F, Drummond GR, Freedman JE, Guzik TJ, Harrison D, Hausenloy DJ, Hill JA, Januzzi JL, Kingwell BA, Lam CSP, MacRae CA, Misselwitz F, Miura T, Ritchie RH, Tomaszewski M, Wu JC, Xiao J, Zannad F. A call to action for new global approaches to cardiovascular disease drug solutions. Eur Heart J. 2021 04 14; 42(15):1464-1475. PMID: 33847746.
    Citations: 1     Fields:    Translation:Humans
  5. Smith KV, Dunning JR, Fischer CM, MacLean TE, Bosque-Hamilton JW, Fera LE, Grant JY, Zelle DJ, Matta L, Gaziano TA, MacRae CA, Scirica BM, Desai AS. Evaluation of the Usage and Dosing of Guideline-Directed Medical Therapy for Heart Failure With Reduced Ejection Fraction Patients in Clinical Practice. J Pharm Pract. 2021 Apr 05; 8971900211004840. PMID: 33813934.
    Citations:    Fields:    
  6. Turan NN, Moshal KS, Roder K, Baggett BC, Kabakov AY, Dhakal S, Teramoto R, Chiang DY, Zhong M, Xie A, Lu Y, Dudley SC, MacRae CA, Karma A, Koren G. The endosomal trafficking regulator LITAF controls the cardiac Nav1.5 channel via the ubiquitin ligase NEDD4-2. J Biol Chem. 2020 Dec 25; 295(52):18148-18159. PMID: 33453823.
  7. Engelbrecht E, MacRae CA, Hla T. Lysolipids in Vascular Development, Biology, and Disease. Arterioscler Thromb Vasc Biol. 2021 02; 41(2):564-584. PMID: 33327749.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  8. MacRae CA, Deo RC, Shaw SY. Ecosystem Barriers to Innovation Adoption in Clinical Practice. Trends Mol Med. 2021 01; 27(1):5-7. PMID: 33293198.
    Citations:    Fields:    
  9. Desai AS, Maclean T, Blood AJ, Bosque-Hamilton J, Dunning J, Fischer C, Fera L, Smith KV, Wagholikar K, Zelle D, Gaziano T, Plutzky J, Scirica B, MacRae CA. Remote Optimization of Guideline-Directed Medical Therapy in Patients With Heart Failure With Reduced Ejection Fraction. JAMA Cardiol. 2020 Dec 01; 5(12):1430-1434. PMID: 32936209.
    Citations: 2     Fields:    
  10. Scirica BM, Cannon CP, Fisher NDL, Gaziano TA, Zelle D, Chaney K, Miller A, Nichols H, Matta L, Gordon WJ, Murphy S, Wagholikar KB, Plutzky J, MacRae CA. Digital Care Transformation: Interim Report From the First 5000 Patients Enrolled in a Remote Algorithm-Based Cardiovascular Risk Management Program to Improve Lipid and Hypertension Control. Circulation. 2021 Feb 02; 143(5):507-509. PMID: 33201729.
    Citations:    Fields:    
  11. Hayashi K, Teramoto R, Nomura A, Asano Y, Beerens M, Kurata Y, Kobayashi I, Fujino N, Furusho H, Sakata K, Onoue K, Chiang DY, Kiviniemi TO, Buys E, Sips P, Burch ML, Zhao Y, Kelly AE, Namura M, Kita Y, Tsuchiya T, Kaku B, Oe K, Takeda Y, Konno T, Inoue M, Fujita T, Kato T, Funada A, Tada H, Hodatsu A, Nakanishi C, Sakamoto Y, Tsuda T, Nagata Y, Tanaka Y, Okada H, Usuda K, Cui S, Saito Y, MacRae CA, Takashima S, Yamagishi M, Kawashiri MA, Takamura M. Impact of functional studies on exome sequence variant interpretation in early-onset cardiac conduction system diseases. Cardiovasc Res. 2020 11 01; 116(13):2116-2130. PMID: 31977013.
    Citations:    Fields:    
  12. Turan NN, Moshal KS, Roder K, Baggett BC, Kabakov AY, Dhakal S, Teramoto R, Chiang DY, Zhong M, Xie A, Lu Y, Dudley SC, MacRae CA, Karma A, Koren G. The endosomal trafficking regulator LITAF controls the cardiac Nav1.5 channel via the ubiquitin ligase NEDD4-2. J Biol Chem. 2020 12 25; 295(52):18148-18159. PMID: 33093176.
    Citations:    Fields:    Translation:HumansAnimalsCells
  13. Kapur S, Sweeney MO, Sauer W, MacRae CA. Non-invasive Thoracic Impedance Changes in COVID-19 Pulmonary Infection. J Cardiovasc Transl Res. 2020 Oct 13. PMID: 33051780.
    Citations: 1     Fields:    
  14. Aryan Z, Szanto A, Pantazi A, Reddi T, Rheinstein C, Powers W, Wilson E, Deo RC, Chowdhury S, Salz L, Dimmock D, Nahas S, Benson W, Kingsmore SF, MacRae CA, Vuzman D. Moving Genomics to Routine Care: An Initial Pilot in Acute Cardiovascular Disease. Circ Genom Precis Med. 2020 10; 13(5):406-416. PMID: 32847406.
    Citations: 1     Fields:    
  15. Burns AR, Luciani GM, Musso G, Bagg R, Yeo M, Zhang Y, Rajendran L, Glavin J, Hunter R, Redman E, Stasiuk S, Schertzberg M, McQuibban GA, Caffrey CR, Cutler SR, Tyers M, Giaever G, Nislow C, Fraser AG, MacRae CA, Gilleard J, Roy PJ. Author Correction: Caenorhabditis elegans is a useful model for anthelmintic discovery. Nat Commun. 2020 07 24; 11(1):3779. PMID: 32709866.
    Citations:    Fields:    
  16. MacRae CA, Califf RM. Reimagining What We Measure in Atherosclerosis-a "Phenotype Stack". Circ Res. 2020 04 24; 126(9):1146-1158. PMID: 32324496.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  17. Lam PY, Kutchukian P, Anand R, Imbriglio J, Andrews C, Padilla H, Vohra A, Lane S, Parker DL, Cornella Taracido I, Johns DG, Beerens M, MacRae CA, Caldwell JP, Sorota S, Asnani A, Peterson RT. Cyp1 Inhibition Prevents Doxorubicin-Induced Cardiomyopathy in a Zebrafish Heart-Failure Model. Chembiochem. 2020 07 01; 21(13):1905-1910. PMID: 32003101.
    Citations: 3     Fields:    Translation:Animals
  18. Lloyd KCK, Adams DJ, Baynam G, Beaudet AL, Bosch F, Boycott KM, Braun RE, Caulfield M, Cohn R, Dickinson ME, Dobbie MS, Flenniken AM, Flicek P, Galande S, Gao X, Grobler A, Heaney JD, Herault Y, de Angelis MH, Lupski JR, Lyonnet S, Mallon AM, Mammano F, MacRae CA, McInnes R, McKerlie C, Meehan TF, Murray SA, Nutter LMJ, Obata Y, Parkinson H, Pepper MS, Sedlacek R, Seong JK, Shiroishi T, Smedley D, Tocchini-Valentini G, Valle D, Wang CL, Wells S, White J, Wurst W, Xu Y, Brown SDM. The Deep Genome Project. Genome Biol. 2020 02 03; 21(1):18. PMID: 32008577.
    Citations: 4     Fields:    Translation:HumansAnimals
  19. Axelsson Raja A, Shi L, Day SM, Russell M, Zahka K, Lever H, Colan SD, Margossian R, Hall EK, Becker J, Jefferies JL, Patel AR, Choudhury L, Murphy AM, Canter C, Bach R, Taylor M, Mestroni L, Wheeler MT, Benson L, Owens AT, Rossano J, Lin KY, Pahl E, Pereira AC, Bundgaard H, Lewis GD, Vargas JD, Cirino AL, McMurray JJV, MacRae CA, Solomon SD, Orav EJ, Braunwald E, Ho CY. Baseline Characteristics of the VANISH Cohort. Circ Heart Fail. 2019 12; 12(12):e006231. PMID: 31813281.
    Citations:    Fields:    Translation:HumansCells
  20. Ghazizadeh Z, Kiviniemi T, Olafsson S, Plotnick D, Beerens ME, Zhang K, Gillon L, Steinbaugh MJ, Barrera V, Sui SH, Werdich AA, Kapur S, Eranti A, Gunn J, Jalkanen J, Airaksinen J, Kleber AG, Hollmén M, MacRae CA. Metastable Atrial State Underlies the Primary Genetic Substrate for MYL4 Mutation-Associated Atrial Fibrillation. Circulation. 2020 01 28; 141(4):301-312. PMID: 31735076.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  21. Blood AJ, Fischer CM, Fera LE, MacLean TE, Smith KV, Dunning JR, Bosque-Hamilton JW, Aronson SJ, Gaziano TA, MacRae CA, Matta LS, Mercurio-Pinto AA, Murphy SN, Scirica BM, Wagholikar K, Desai AS. Rationale and design of a navigator-driven remote optimization of guideline-directed medical therapy in patients with heart failure with reduced ejection fraction. Clin Cardiol. 2020 Jan; 43(1):4-13. PMID: 31725920.
    Citations: 2     Fields:    Translation:Humans
  22. Harris S, Cirino AL, Carr CW, Tafessu HM, Parmar S, Greenberg JO, Szent-Gyorgyi LE, Ghazinouri R, Glowny MG, McNeil K, Kaynor EF, Neumann C, Seidman CE, MacRae CA, Ho CY, Lakdawala NK. The uptake of family screening in hypertrophic cardiomyopathy and an online video intervention to facilitate family communication. Mol Genet Genomic Med. 2019 11; 7(11):e940. PMID: 31482667.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  23. Moshal KS, Roder K, Kabakov AY, Werdich AA, Chiang DY, Turan NN, Xie A, Kim TY, Cooper LL, Lu Y, Zhong M, Li W, Terentyev D, Choi BR, Karma A, MacRae CA, Koren G. LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor) Regulates Cardiac L-Type Calcium Channels by Modulating NEDD (Neural Precursor Cell Expressed Developmentally Downregulated Protein) 4-1 Ubiquitin Ligase. Circ Genom Precis Med. 2019 09; 12(9):407-420. PMID: 31462068.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  24. MacRae CA. Closing the 'phenotype gap' in precision medicine: improving what we measure to understand complex disease mechanisms. Mamm Genome. 2019 08; 30(7-8):201-211. PMID: 31428846.
    Citations: 3     Fields:    Translation:HumansAnimals
  25. MacRae CA. Evolution of academic-industry partnerships in cardiovascular research and development. Nat Rev Cardiol. 2019 08; 16(8):449-451. PMID: 31197233.
    Citations:    Fields:    Translation:Humans
  26. DeWitt ES, Chandler SF, Hylind RJ, Beausejour Ladouceur V, Blume ED, VanderPluym C, Powell AJ, Fynn-Thompson F, Roberts AE, Sanders SP, Bezzerides V, Lakdawala NK, MacRae CA, Abrams DJ. Phenotypic Manifestations of Arrhythmogenic Cardiomyopathy in Children and Adolescents. J Am Coll Cardiol. 2019 07 23; 74(3):346-358. PMID: 31319917.
    Citations: 8     Fields:    Translation:Humans
  27. Aday AW, Krier JB, Pallais JC, Fieg EL, MacRae CA, Loscalzo J. The Undiagnosed Diseases Network as a Tool for Graduate Medical Education. Am J Med. 2020 02; 133(2):e18-e22. PMID: 31301294.
    Citations:    Fields:    Translation:Humans
  28. Landmesser U, MacRae CA. Digital technology to support self-management in patients with coronary disease. Lancet Digit Health. 2019 06; 1(2):e50-e51. PMID: 33323228.
    Citations:    Translation:Humans
  29. Wagholikar KB, Fischer CM, Goodson AP, Herrick CD, Maclean TE, Smith KV, Fera L, Gaziano TA, Dunning JR, Bosque-Hamilton J, Matta L, Toscano E, Richter B, Ainsworth L, Oates MF, Aronson S, MacRae CA, Scirica BM, Desai AS, Murphy SN. Phenotyping to Facilitate Accrual for a Cardiovascular Intervention. J Clin Med Res. 2019 Jun; 11(6):458-463. PMID: 31143314.
    Citations: 1     
  30. Wagholikar KB, Ainsworth L, Vernekar VP, Pathak A, Glynn C, Zelle D, Zagade A, Karipineni N, Herrick CD, McPartlin M, Bui TV, Mendis M, Klann J, Oates M, Gordon W, Cannon C, Patel R, Aronson SJ, MacRae CA, Scirica BM, Murphy SN. Extending i2b2 into a framework for semantic abstraction of EHR to facilitate rapid development and portability of Health IT applications. AMIA Jt Summits Transl Sci Proc. 2019; 2019:370-378. PMID: 31258990.
    Citations: 2     
  31. Mishra S, Joshi S, Ward JE, Buys EP, Mishra D, Mishra D, Morgado I, Fisch S, Lavatelli F, Merlini G, Dorbala S, MacRae CA, Liao R. Zebrafish model of amyloid light chain cardiotoxicity: regeneration versus degeneration. . 2019 05 01; 316(5):H1158-H1166. PMID: 30875258.
    Citations: 6     Translation:HumansAnimals
  32. Zhao Y, Zhang K, Sips P, MacRae CA. Screening drugs for myocardial disease in vivo with zebrafish: an expert update. Expert Opin Drug Discov. 2019 04; 14(4):343-353. PMID: 30836799.
    Citations: 1     Fields:    Translation:HumansAnimals
  33. Hylind RJ, Chandler SF, Beausejour Ladouceur V, Roberts AE, Bezzerides V, Christensen KD, Coggins M, Lakdawala NK, MacRae CA, Abrams DJ. Phenotypic Characterization of Individuals With Variants in Cardiovascular Genes in the Absence of a Primary Cardiovascular Indication for Testing. Circ Genom Precis Med. 2019 03; 12(3):e002463. PMID: 30919684.
    Citations:    Fields:    Translation:Humans
  34. Fisher NDL, Fera LE, Dunning JR, Desai S, Matta L, Liquori V, Pagliaro J, Pabo E, Merriam M, MacRae CA, Scirica BM. Development of an entirely remote, non-physician led hypertension management program. Clin Cardiol. 2019 Feb; 42(2):285-291. PMID: 30582181.
    Citations: 6     Fields:    Translation:Humans
  35. Roder K, Kabakov A, Moshal KS, Murphy KR, Xie A, Dudley S, Turan NN, Lu Y, MacRae CA, Koren G. Trafficking of the human ether-a-go-go-related gene (hERG) potassium channel is regulated by the ubiquitin ligase rififylin (RFFL). J Biol Chem. 2019 01 04; 294(1):351-360. PMID: 30401747.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  36. Feghaly J, Zakka P, London B, MacRae CA, Refaat MM. Genetics of Atrial Fibrillation. J Am Heart Assoc. 2018 10 16; 7(20):e009884. PMID: 30371258.
    Citations: 10     Fields:    Translation:HumansCells
  37. Seidelmann SB, Feofanova E, Yu B, Franceschini N, Claggett B, Kuokkanen M, Puolijoki H, Ebeling T, Perola M, Salomaa V, Shah A, Coresh J, Selvin E, MacRae CA, Cheng S, Boerwinkle E, Solomon SD. Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk. J Am Coll Cardiol. 2018 10 09; 72(15):1763-1773. PMID: 30286918.
    Citations: 8     Fields:    Translation:Humans
  38. Morningstar J, Lee J, Hendry-Hofer T, Witeof A, Lyle LT, Knipp G, MacRae CA, Boss GR, Peterson RT, Davisson VJ, Gerszten RE, Bebarta VS, Mahon S, Brenner M, Nath AK. Intramuscular administration of hexachloroplatinate reverses cyanide-induced metabolic derangements and counteracts severe cyanide poisoning. FASEB Bioadv. 2019 Feb; 1(2):81-92. PMID: 31355359.
    Citations: 1     
  39. Wagholikar KB, Fischer CM, Goodson A, Herrick CD, Rees M, Toscano E, MacRae CA, Scirica BM, Desai AS, Murphy SN. Extraction of Ejection Fraction from Echocardiography Notes for Constructing a Cohort of Patients having Heart Failure with reduced Ejection Fraction (HFrEF). J Med Syst. 2018 Sep 25; 42(11):209. PMID: 30255347.
    Citations: 7     Fields:    Translation:Humans
  40. Macrae CA. Rare Diseases Inform Myocardial Phenotypes for Precision Medicine. J Card Fail. 2018 10; 24(10):680-681. PMID: 30218700.
    Citations:    Fields:    Translation:Humans
  41. Haghighi A, Krier JB, Toth-Petroczy A, Cassa CA, Frank NY, Carmichael N, Fieg E, Bjonnes A, Mohanty A, Briere LC, Lincoln S, Lucia S, Gupta VA, Söylemez O, Sutti S, Kooshesh K, Qiu H, Fay CJ, Perroni V, Valerius J, Hanna M, Frank A, Ouahed J, Snapper SB, Pantazi A, Chopra SS, Leshchiner I, Stitziel NO, Feldweg A, Mannstadt M, Loscalzo J, Sweetser DA, Liao E, Stoler JM, Nowak CB, Sanchez-Lara PA, Klein OD, Perry H, Patsopoulos NA, Raychaudhuri S, Goessling W, Green RC, Seidman CE, MacRae CA, Sunyaev SR, Maas RL, Vuzman D. An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery. NPJ Genom Med. 2018; 3:21. PMID: 30131872.
    Citations: 5     
  42. Dempsey J, Gillis C, Sibicky S, Matta L, MacRae C, Kirshenbaum J, Faxon D, Churchill W. Evaluation of a transitional care pharmacist intervention in a high-risk cardiovascular patient population. Am J Health Syst Pharm. 2018 Sep 01; 75(17 Supplement 3):S63-S71. PMID: 29976830.
    Citations: 5     Fields:    Translation:Humans
  43. Kithcart AP, MacRae CA. Zebrafish assay development for cardiovascular disease mechanism and drug discovery. Prog Biophys Mol Biol. 2018 10; 138:126-131. PMID: 30518489.
    Citations: 2     Fields:    Translation:HumansAnimals
  44. Sips PY, Shi X, Musso G, Nath AK, Zhao Y, Nielson J, Morningstar J, Kelly AE, Mikell B, Buys E, Bebarta V, Rutter J, Davisson VJ, Mahon S, Brenner M, Boss GR, Peterson RT, Gerszten RE, MacRae CA. Identification of specific metabolic pathways as druggable targets regulating the sensitivity to cyanide poisoning. PLoS One. 2018; 13(6):e0193889. PMID: 29879736.
    Citations: 3     Fields:    Translation:Animals
  45. Musunuru K, Arora P, Cooke JP, Ferguson JF, Hershberger RE, Hickey KT, Lee JM, Lima JAC, Loscalzo J, Pereira NL, Russell MW, Shah SH, Sheikh F, Wang TJ, MacRae CA. Interdisciplinary Models for Research and Clinical Endeavors in Genomic Medicine: A Scientific Statement From the American Heart Association. Circ Genom Precis Med. 2018 06; 11(6):e000046. PMID: 29844141.
    Citations: 2     Fields:    Translation:Humans
  46. Kapur S, Kumar S, John RM, Stevenson WG, Tedrow UB, Koplan BA, Epstein LM, MacRae CA, Michaud GF. Family history of atrial fibrillation as a predictor of atrial substrate and arrhythmia recurrence in patients undergoing atrial fibrillation catheter ablation. Europace. 2018 06 01; 20(6):921-928. PMID: 28541417.
    Citations: 2     Fields:    Translation:Humans
  47. Cranley J, MacRae CA. A New Approach to an Old Problem: One Brave Idea. Circ Res. 2018 04 27; 122(9):1172-1175. PMID: 29700065.
    Citations: 3     Fields:    Translation:HumansCells
  48. Colombo S, de Sena-Tomás C, George V, Werdich AA, Kapur S, MacRae CA, Targoff KL. Nkx genes establish second heart field cardiomyocyte progenitors at the arterial pole and pattern the venous pole through Isl1 repression. Development. 2018 02 05; 145(3). PMID: 29361575.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  49. Oldham WM, Oliveira RKF, Wang RS, Opotowsky AR, Rubins DM, Hainer J, Wertheim BM, Alba GA, Choudhary G, Tornyos A, MacRae CA, Loscalzo J, Leopold JA, Waxman AB, Olschewski H, Kovacs G, Systrom DM, Maron BA. Network Analysis to Risk Stratify Patients With Exercise Intolerance. Circ Res. 2018 03 16; 122(6):864-876. PMID: 29437835.
    Citations: 14     Fields:    Translation:Humans
  50. Natarajan N, Abbas Y, Bryant DM, Gonzalez-Rosa JM, Sharpe M, Uygur A, Cocco-Delgado LH, Ho NN, Gerard NP, Gerard CJ, MacRae CA, Burns CE, Burns CG, Whited JL, Lee RT. Complement Receptor C5aR1 Plays an Evolutionarily Conserved Role in Successful Cardiac Regeneration. Circulation. 2018 05 15; 137(20):2152-2165. PMID: 29348261.
    Citations: 18     Fields:    Translation:AnimalsCells
  51. Nikolova-Krstevski V, Wagner S, Yu ZY, Cox CD, Cvetkovska J, Hill AP, Huttner IG, Benson V, Werdich AA, MacRae C, Feneley MP, Friedrich O, Martinac B, Fatkin D. Endocardial TRPC-6 Channels Act as Atrial Mechanosensors and Load-Dependent Modulators of Endocardial/Myocardial Cross-Talk. JACC Basic Transl Sci. 2017 Oct; 2(5):575-590. PMID: 30062171.
    Citations: 7     
  52. MacRae CA, Seidman CE. Closing the Genotype-Phenotype Loop for Precision Medicine. Circulation. 2017 10 17; 136(16):1492-1494. PMID: 29038206.
    Citations: 3     Fields:    Translation:HumansCells
  53. Cirino AL, Lakdawala NK, McDonough B, Conner L, Adler D, Weinfeld M, O'Gara P, Rehm HL, Machini K, Lebo M, Blout C, Green RC, MacRae CA, Seidman CE, Ho CY. A Comparison of Whole Genome Sequencing to Multigene Panel Testing in Hypertrophic Cardiomyopathy Patients. Circ Cardiovasc Genet. 2017 Oct; 10(5). PMID: 29030401.
    Citations: 17     Fields:    Translation:HumansCells
  54. MacRae CA. Skin and Vascular Disease-Inside-Out/Outside-In. JAMA Cardiol. 2017 09 01; 2(9):944-945. PMID: 28564684.
    Citations:    Fields:    Translation:Humans
  55. Aday AW, MacRae CA. Genomic Medicine in Cardiovascular Fellowship Training. Circulation. 2017 07 25; 136(4):345-346. PMID: 28739809.
    Citations: 2     Fields:    Translation:Humans
  56. Ito K, Patel PN, Gorham JM, McDonough B, DePalma SR, Adler EE, Lam L, MacRae CA, Mohiuddin SM, Fatkin D, Seidman CE, Seidman JG. Identification of pathogenic gene mutations in LMNA and MYBPC3 that alter RNA splicing. Proc Natl Acad Sci U S A. 2017 07 18; 114(29):7689-7694. PMID: 28679633.
    Citations: 14     Fields:    Translation:HumansCells
  57. Vassy JL, Christensen KD, Schonman EF, Blout CL, Robinson JO, Krier JB, Diamond PM, Lebo M, Machini K, Azzariti DR, Dukhovny D, Bates DW, MacRae CA, Murray MF,