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Gyorgy Baffy, M.D., Ph.D.

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Biography
University of Debrecen, Debrecen, HungaryMD1980Medicine
University of Debrecen, Debrecen, Hungary1987Gastroenterology
University of Pennsylvania, Philadelphia, PA1993Biochemistry
National Academy of Sciences, Budapest, HungaryPhD1994Medicine
University of Michigan, Ann Arbor, MI1996Gastroenterology
Brigham and Women's Hospital, Boston, MA2001Gastroenterology
1990
OMGE Young Investigator Scholarship
1991 - 1993
NIH Fogarty Fellow
1994
Rolf Madaus Prize
2010
Geza Hetenyi Award
2014 - 2015
US Fulbright Scholar Award
2017
Pro Optimo Merito in Gastroenterologia

Overview
Dr. Gyorgy Baffy is an Associate Professor of Medicine at Harvard Medical School and Chief of Gastroenterology at the VA Boston Healthcare System. He is a graduate of the University Medical School of Debrecen in Hungary. He received his PhD from his studies conducted on growth factor-mediated calcium signaling in hepatocytes as an NIH Fogarty Fellow in the Department of Biochemistry and Biophysics at the University of Pennsylvania. He trained in gastroenterology at the University of Michigan and the Brigham and Women’s Hospital. His research interests focus on various aspects of NAFLD such as risk stratification, biomarkers, metabolic reprogramming, cancer bioenergetics, pathophysiology of portal hypertension, and development of hepatocellular carcinoma. He has been involved in several clinical trials related to cirrhosis management and colorectal cancer screening. He developed and organized multiple regional, national, and international workshops and symposia. He published over 100 peer-reviewed papers and book chapters. He has been a member of various scientific review panels and provides editorial work for major journals in gastroenterology and hepatology. In 2014, he received a Fulbright US Scholar award to teach for a semester about obesity and related disorders at the University of Debrecen. He is a Fellow of the American College of Physicians, American College of Gastroenterology, American Gastroenterological Association, and the American Association for the Study of Liver Diseases. He is the recipient of the Madaus Prize from the Madaus Liver Foundation and the Hetényi Medal and Pro Optimo Merito in Gastroenterologia Award from the Hungarian Gastroenterological Association.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. CSP-2023 (IOANNOU, GEORGE / TADDEI, TAMAR) May 1, 2023 - Apr 30, 2032
    VA Office of Research & Development Cooperative Studies Program
    PREventing Liver Cancer Mortality through Imaging with Ultrasound vs. MRI (PREMIUM)
    Role Description: The main objective of this multicenter randomized controlled trial is to compare the efficacy of biannual ultrasound plus alpha-fetoprotein (AFP) vs. biannual abbreviated magnetic resonance imaging (MRI) plus AFP as cancer screening modalities for patients with cirrhosis with a primary outcome of HCC-related mortality.
    Role: Site Investigator
  2. 1I01 CX002010 (KAPLAN, DAVID / TADDEI, TAMAR) Oct 1, 2020 - Sep 30, 2025
    VA ORD Clinical Science Research & Development
    Effect of simvastatin on hepatic decompensation and death in subjects with high- risk compensated cirrhosis (SACRED: Statins and Cirrhosis: Reducing Events of Decompensation
    Role Description: The primary objective of this phase III, randomized, double-blind, placebo-controlled, multicenter trial is to demonstrate that statin therapy can reduce the rate of hepatic decompensation, hepatocellular carcinoma, all-cause mortality, and the need for liver transplantation
    Role: Site Investigator
  3. PAL-LIVER (NAVARRO, VICTOR / VERMA, MANISHA) Oct 1, 2017 - Sep 30, 2025
    Patient-Centered Outcomes Research Institute (PCORI)
    Introducing palliative care with the treatment of end stage liver disease: A randomized controlled trial
    Role Description: The main goal of this multicenter cluster randomized clinical project is to determine the benefits of hepatologist-led palliative care compared to the conventional approach of requesting palliative care consultations in the management of patients with end-stage liver disease
    Role: Site Investigator
  4. CSP-577 (DOMINITZ, JASON / ROBERTSON, DOUGLAS) May 1, 2012 - Sep 30, 2027
    VA Cooperative Studies
    Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM)
    Role Description: The main goal of this study is to perform a large, simple, multicenter, randomized, parallel group trial directly comparing screening colonoscopy with annual fecal immunochemistry test (FIT) screening in 50,000 average risk individuals and determine whether colonoscopy is superior to FIT in the prevention of colorectal cancer mortality measured over 10 years.
    Role: Site Investigator

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.