Harvard Catalyst Profiles

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Richard Jonathan Cohen, Ph.D., M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. P01HL068758 (RUDERMAN, NEIL B) May 1, 2003 - Jan 31, 2015
    NIH/NHLBI
    AMPK Endothelial Cell Dysfunction and the Metabolic Syndrome (PROGRAM PROJECT)
    Role: Co-Principal Investigator
  2. R01HL039291 (COHEN, RICHARD J) Apr 1, 1989 - Mar 31, 1994
    NIH/NHLBI
    BEAT-TO-BEAT VARIABILITY IN HEMODYNAMIC PARAMETERS
    Role: Principal Investigator
  3. M01RR000088 (GRAY, MARTHA L) Nov 30, 2001
    NIH/NCRR
    GENERAL CLINICAL RESEARCH CENTER
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lv W, Lee K, Arai T, Barrett CD, Hasan MM, Hayward AM, Marini RP, Barley ME, Galea A, Hirschman G, Armoundas AA, Cohen RJ. Accuracy of cardiac ablation catheter guidance by means of a single equivalent moving dipole inverse algorithm to identify sites of origin of cardiac electrical activation. J Interv Card Electrophysiol. 2019 Aug 27. PMID: 31456103.
    Citations:    
  2. Arai T, Lee K, Cohen RJ. Comparison of cardiovascular parameter estimation methods using swine data. J Clin Monit Comput. 2020 Apr; 34(2):261-270. PMID: 31104305.
    Citations:    
  3. Meglan DA, Lv W, Cohen RJ, Riviere CN. Techniques for epicardial mapping and ablation with a miniature robotic walker. Robot Surg. 2017; 4:25-31. PMID: 28966928.
    Citations: 1     
  4. Merchant FM, Salerno-Uriarte JA, Caravati F, Falcone S, Molon G, Marangoni D, Raczak G, Danilowicz-Szymanowicz L, Pedretti RF, Sarzi Braga S, Ikeda T, Calo L, Martino A, Erciyes D, Piancastelli M, Maury P, Cohen RJ, Armoundas AA. Prospective Use of Microvolt T-Wave Alternans Testing to Guide Primary Prevention Implantable Cardioverter Defibrillator Therapy. Circ J. 2015; 79(9):1912-9. PMID: 26073692.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  5. Sohn K, Lv W, Lee K, Galea A, Hirschman G, Barrett C, Cohen RJ, Armoundas AA. A method to noninvasively identify cardiac bioelectrical sources. Pacing Clin Electrophysiol. 2014 Aug; 37(8):1038-50. PMID: 24645803.
    Citations: 1     Fields:    Translation:Animals
  6. Sohn K, Lv W, Lee K, Galea AM, Hirschman GB, Hayward AM, Cohen RJ, Armoundas AA. The single equivalent moving dipole model does not require spatial anatomical information to determine cardiac sources of activation. IEEE J Biomed Health Inform. 2014 Jan; 18(1):222-30. PMID: 24403420.
    Citations: 1     Fields:    Translation:Animals
  7. Molon G, Cohen RJ, de Santo T, Costa A, Barbieri E. Clinical use of microvolt T-wave alternans in patients with depressed left ventricular function eligible for ICD implantation: mortality outcomes after long term follow-up. Int J Cardiol. 2013 Oct 03; 168(3):3038-40. PMID: 23643438.
    Citations: 2     Fields:    Translation:Humans
  8. Kim YK, Lee K, Hwang GS, Cohen RJ. Sympathetic withdrawal is associated with hypotension after hepatic reperfusion. Clin Auton Res. 2013 Jun; 23(3):123-31. PMID: 23467970.
    Citations: 5     Fields:    Translation:Humans
  9. Lee K, Lv W, Ter-Ovanesyan E, Barley ME, Voysey GE, Galea AM, Hirschman GB, Leroy K, Marini RP, Barrett C, Armoundas AA, Cohen RJ. Cardiac ablation catheter guidance by means of a single equivalent moving dipole inverse algorithm. Pacing Clin Electrophysiol. 2013 Jul; 36(7):811-22. PMID: 23448231.
    Citations: 3     Fields:    Translation:Animals
  10. Hohnloser SH, Cohen RJ. Microvolt T-wave alternans testing provides a reliable means of guiding anti-arrhythmic therapy. Am Heart J. 2012 Oct; 164(4):e7; author reply e9-e10. PMID: 23067926.
    Citations: 1     Fields:    Translation:Humans
  11. Hohnloser SH, Cohen RJ. Microvolt T-wave alternans testing should be used to guide arrhythmic therapy in heart failure patients. Eur J Heart Fail. 2012 Jun; 14(6):677-8; author reply 678. PMID: 22628438.
    Citations:    Fields:    Translation:Humans
  12. Arai T, Lee K, Marini RP, Cohen RJ. Estimation of changes in instantaneous aortic blood flow by the analysis of arterial blood pressure. J Appl Physiol (1985). 2012 Jun; 112(11):1832-8. PMID: 22442022.
    Citations:    Fields:    Translation:Animals
  13. Merchant FM, Ikeda T, Pedretti RF, Salerno-Uriarte JA, Chow T, Chan PS, Bartone C, Hohnloser SH, Cohen RJ, Armoundas AA. Clinical utility of microvolt T-wave alternans testing in identifying patients at high or low risk of sudden cardiac death. Heart Rhythm. 2012 Aug; 9(8):1256-64.e2. PMID: 22406384.
    Citations: 17     Fields:    Translation:Humans
  14. Eisen HN, Hou XH, Shen C, Wang K, Tanguturi VK, Smith C, Kozyrytska K, Nambiar L, McKinley CA, Chen J, Cohen RJ. Promiscuous binding of extracellular peptides to cell surface class I MHC protein. Proc Natl Acad Sci U S A. 2012 Mar 20; 109(12):4580-5. PMID: 22403068.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  15. Arai T, Lee K, Cohen RJ. Cardiac output and stroke volume estimation using a hybrid of three Windkessel models. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:4971-4. PMID: 21096675.
    Citations: 4     Fields:    Translation:Humans
  16. Barley ME, Armoundas AA, Cohen RJ. A method for guiding ablation catheters to arrhythmogenic sites using body surface electrocardiographic signals. IEEE Trans Biomed Eng. 2009 Mar; 56(3):810-9. PMID: 19272900.
    Citations: 3     Fields:    Translation:Humans
  17. Barley ME, Choppy KJ, Galea AM, Armoundas AA, Rosbury TS, Hirschman GB, Cohen RJ. Validation of a novel catheter guiding method for the ablative therapy of ventricular tachycardia in a phantom model. IEEE Trans Biomed Eng. 2009 Mar; 56(3):907-10. PMID: 19272901.
    Citations: 3     Fields:    
  18. Hohnloser SH, Ikeda T, Cohen RJ. Evidence regarding clinical use of microvolt T-wave alternans. Heart Rhythm. 2009 Mar; 6(3 Suppl):S36-44. PMID: 19168396.
    Citations: 21     Fields:    Translation:HumansPHPublic Health
  19. Esperer HD, Esperer C, Cohen RJ. Cardiac arrhythmias imprint specific signatures on Lorenz plots. Ann Noninvasive Electrocardiol. 2008 Jan; 13(1):44-60. PMID: 18234006.
    Citations: 7     Fields:    Translation:Humans
  20. Kaufman ES, Bloomfield DM, Steinman RC, Namerow PB, Costantini O, Cohen RJ, Bigger JT. "Indeterminate" microvolt T-wave alternans tests predict high risk of death or sustained ventricular arrhythmias in patients with left ventricular dysfunction. J Am Coll Cardiol. 2006 Oct 03; 48(7):1399-404. PMID: 17010802.
    Citations: 18     Fields:    Translation:HumansCTClinical Trials
  21. Xiao X, Mukkamala R, Cohen RJ. A weighted-principal component regression method for the identification of physiologic systems. IEEE Trans Biomed Eng. 2006 Aug; 53(8):1521-30. PMID: 16916086.
    Citations: 2     Fields:    Translation:HumansAnimals
  22. Grenon SM, Xiao X, Hurwitz S, Sheynberg N, Kim C, Seely EW, Cohen RJ, Williams GH. Why is orthostatic tolerance lower in women than in men? Renal and cardiovascular responses to simulated microgravity and the role of midodrine. J Investig Med. 2006 May; 54(4):180-90. PMID: 17152857.
    Citations: 7     Fields:    Translation:Humans
  23. Mukkamala R, Reisner AT, Hojman HM, Mark RG, Cohen RJ. Continuous cardiac output monitoring by peripheral blood pressure waveform analysis. IEEE Trans Biomed Eng. 2006 Mar; 53(3):459-67. PMID: 16532772.
    Citations: 12     Fields:    Translation:Animals
  24. Barley ME, Cohen RJ. High-precision guidance of ablation catheters to arrhythmic sites using electrocardiographic signals. Conf Proc IEEE Eng Med Biol Soc. 2006; 2006:6297-300. PMID: 17945952.
    Citations: 1     Fields:    Translation:Humans
  25. Xiao X, Grenon SM, Kim C, Sheynberg N, Hurwitz S, Williams GH, Cohen RJ. Bed rest effects on human calf hemodynamics and orthostatic intolerance: a model-based analysis. Aviat Space Environ Med. 2005 Nov; 76(11):1037-45. PMID: 16315396.
    Citations: 3     Fields:    Translation:Humans
  26. Armoundas AA, Hohnloser SH, Ikeda T, Cohen RJ. Can microvolt T-wave alternans testing reduce unnecessary defibrillator implantation? Nat Clin Pract Cardiovasc Med. 2005 Oct; 2(10):522-8. PMID: 16186850.
    Citations: 13     Fields:    Translation:Humans
  27. Grenon SM, Xiao X, Hurwitz S, Ramsdell CD, Sheynberg N, Kim C, Williams GH, Cohen RJ. Simulated microgravity induces microvolt T wave alternans. Ann Noninvasive Electrocardiol. 2005 Jul; 10(3):363-70. PMID: 16029389.
    Citations: 5     Fields:    Translation:Humans
  28. Grenon SM, Hurwitz S, Xiao X, Sheynberg N, Ramsdell CD, Kim C, Cohen RJ, Williams GH. Readaptation from simulated microgravity as a stimulus for improved orthostatic tolerance: role of the renal, cardioendocrine, and cardiovascular systems. J Investig Med. 2005 Mar; 53(2):82-91. PMID: 15810494.
    Citations: 2     Fields:    Translation:Humans
  29. Grenon SM, Hurwitz S, Sheynberg N, Xiao X, Judson B, Ramsdell CD, Kim C, Cohen RJ, Williams GH. Sleep restriction does not affect orthostatic tolerance in the simulated microgravity environment. J Appl Physiol (1985). 2004 Nov; 97(5):1660-6. PMID: 15234956.
    Citations:    Fields:    Translation:Humans
  30. Aljuri N, Marini R, Cohen RJ. Test of dynamic closed-loop baroreflex and autoregulatory control of total peripheral resistance in intact and conscious sheep. Am J Physiol Heart Circ Physiol. 2004 Nov; 287(5):H2274-86. PMID: 15231504.
    Citations: 2     Fields:    Translation:Animals
  31. Aljuri N, Cohen RJ. Theoretical considerations in the dynamic closed-loop baroreflex and autoregulatory control of total peripheral resistance. Am J Physiol Heart Circ Physiol. 2004 Nov; 287(5):H2252-73. PMID: 15231503.
    Citations: 4     Fields:    Translation:Humans
  32. Cohen RJ, Fox DL, Salvatore RN. A novel and highly efficient synthetic route to unsymmetrical organoselenides using cesium bases. J Org Chem. 2004 Jun 11; 69(12):4265-8. PMID: 15176857.
    Citations: 2     Fields:    
  33. Armoundas AA, Albert CM, Cohen RJ, Mela T. Utility of implantable cardioverter defibrillator electrograms to estimate repolarization alternans preceding a tachyarrhythmic event. J Cardiovasc Electrophysiol. 2004 May; 15(5):594-7. PMID: 15149432.
    Citations: 5     Fields:    Translation:Humans
  34. Grenon SM, Hurwitz S, Sheynberg N, Xiao X, Ramsdell CD, Mai CL, Kim C, Cohen RJ, Williams GH. Role of individual predisposition in orthostatic intolerance before and after simulated microgravity. J Appl Physiol (1985). 2004 May; 96(5):1714-22. PMID: 15075309.
    Citations: 3     Fields:    Translation:Humans
  35. Grenon SM, Sheynberg N, Hurwitz S, Xiao G, Ramsdell CD, Ehrman MD, Mai CL, Kristjansson SR, Sundby GH, Cohen RJ, Williams GH. Renal, endocrine, and cardiovascular responses to bed rest in male subjects on a constant diet. J Investig Med. 2004 Mar; 52(2):117-28. PMID: 15068228.
    Citations: 4     Fields:    Translation:Humans
  36. Hurwitz S, Cohen RJ, Williams GH. Diurnal variation of aldosterone and plasma renin activity: timing relation to melatonin and cortisol and consistency after prolonged bed rest. J Appl Physiol (1985). 2004 Apr; 96(4):1406-14. PMID: 14660513.
    Citations: 23     Fields:    Translation:Humans
  37. Armoundas AA, Feldman AB, Mukkamala R, He B, Mullen TJ, Belk PA, Lee YZ, Cohen RJ. Statistical accuracy of a moving equivalent dipole method to identify sites of origin of cardiac electrical activation. IEEE Trans Biomed Eng. 2003 Dec; 50(12):1360-70. PMID: 14656065.
    Citations: 8     Fields:    Translation:Animals
  38. Cohen RJ. Enhancing specificity without sacrificing sensitivity: potential benefits of using microvolt T-wave alternans testing to risk stratify the MADIT-II population. Card Electrophysiol Rev. 2003 Dec; 7(4):438-42. PMID: 15071271.
    Citations: 3     Fields:    Translation:Humans
  39. Radisic M, Yang L, Boublik J, Cohen RJ, Langer R, Freed LE, Vunjak-Novakovic G. Medium perfusion enables engineering of compact and contractile cardiac tissue. Am J Physiol Heart Circ Physiol. 2004 Feb; 286(2):H507-16. PMID: 14551059.
    Citations: 70     Fields:    Translation:AnimalsCells
  40. Xiao X, Mukkamala R, Sheynberg N, Grenon SM, Ehrman MD, Mullen TJ, Ramsdell CD, Williams GH, Cohen RJ. Effects of simulated microgravity on closed-loop cardiovascular regulation and orthostatic intolerance: analysis by means of system identification. J Appl Physiol (1985). 2004 Feb; 96(2):489-97. PMID: 14514703.
    Citations:    Fields:    Translation:Humans
  41. Hohnloser SH, Ikeda T, Bloomfield DM, Dabbous OH, Cohen RJ. T-wave alternans negative coronary patients with low ejection and benefit from defibrillator implantation. Lancet. 2003 Jul 12; 362(9378):125-6. PMID: 12867114.
    Citations: 28     Fields:    Translation:Humans
  42. Hohnloser SH, Klingenheben T, Bloomfield D, Dabbous O, Cohen RJ. Usefulness of microvolt T-wave alternans for prediction of ventricular tachyarrhythmic events in patients with dilated cardiomyopathy: results from a prospective observational study. J Am Coll Cardiol. 2003 Jun 18; 41(12):2220-4. PMID: 12821251.
    Citations: 21     Fields:    Translation:Humans
  43. Armoundas AA, Feldman AB, Mukkamala R, Cohen RJ. A single equivalent moving dipole model: an efficient approach for localizing sites of origin of ventricular electrical activation. Ann Biomed Eng. 2003 May; 31(5):564-76. PMID: 12757200.
    Citations: 16     Fields:    Translation:Humans
  44. Mukkamala R, Toska K, Cohen RJ. Noninvasive identification of the total peripheral resistance baroreflex. Am J Physiol Heart Circ Physiol. 2003 Mar; 284(3):H947-59. PMID: 12433656.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  45. Cheung MM, Weintraub RG, Cohen RJ, Karl TR, Wilkinson JL, Davis AM. T wave alternans threshold late after repair of tetralogy of Fallot. J Cardiovasc Electrophysiol. 2002 Jul; 13(7):657-61. PMID: 12139287.
    Citations: 3     Fields:    Translation:Humans
  46. Bloomfield DM, Hohnloser SH, Cohen RJ. Interpretation and classification of microvolt T wave alternans tests. J Cardiovasc Electrophysiol. 2002 May; 13(5):502-12. PMID: 12030535.
    Citations: 37     Fields:    Translation:Humans
  47. Armoundas AA, Ju K, Iyengar N, Kanters JK, Saul PJ, Cohen RJ, Chon KH. A stochastic nonlinear autoregressive algorithm reflects nonlinear dynamics of heart-rate fluctuations. Ann Biomed Eng. 2002 Feb; 30(2):192-201. PMID: 11962771.
    Citations: 5     Fields:    Translation:Humans
  48. Mukkamala R, Cohen RJ, Mark RG. A computational model-based validation of Guyton's analysis of cardiac output and venous return curves. Comput Cardiol. 2002; 29:561-4. PMID: 14686453.
    Citations:    Translation:Humans
  49. Xiao X, Mukkamala R, Sheynberg N, Williams GH, Cohen RJ. Effects of prolonged bed rest on the total peripheral resistance baroreflex. Comput Cardiol. 2002; 29:53-6. PMID: 14686446.
    Citations: 2     Translation:Humans
  50. Mukkamala R, Cohen RJ. A forward model-based validation of cardiovascular system identification. Am J Physiol Heart Circ Physiol. 2001 Dec; 281(6):H2714-30. PMID: 11709441.
    Citations: 8     Fields:    Translation:Humans
  51. Elstad M, Toska K, Chon KH, Raeder EA, Cohen RJ. Respiratory sinus arrhythmia: opposite effects on systolic and mean arterial pressure in supine humans. J Physiol. 2001 Oct 01; 536(Pt 1):251-9. PMID: 11579173.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  52. Armoundas AA, Feldman AB, Sherman DA, Cohen RJ. Applicability of the single equivalent point dipole model to represent a spatially distributed bio-electrical source. Med Biol Eng Comput. 2001 Sep; 39(5):562-70. PMID: 11712653.
    Citations: 5     Fields:    
  53. Aljuri AN, Bursac N, Marini R, Cohen RJ. System identification of dynamic closed-loop control of total peripheral resistance by arterial and cardiopulmonary baroreceptors. Acta Astronaut. 2001 Aug-Nov; 49(3-10):167-70. PMID: 11669106.
    Citations:    Fields:    Translation:AnimalsCells
  54. Ramsdell CD, Mullen TJ, Sundby GH, Rostoft S, Sheynberg N, Aljuri N, Maa M, Mukkamala R, Sherman D, Toska K, Yelle J, Bloomfield D, Williams GH, Cohen RJ. Midodrine prevents orthostatic intolerance associated with simulated spaceflight. J Appl Physiol (1985). 2001 Jun; 90(6):2245-8. PMID: 11356789.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  55. Cheung MM, Davis AM, Cohen RJ, Wilkinson JL. T wave alternans threshold in normal children. J Cardiovasc Electrophysiol. 2001 Apr; 12(4):424-7. PMID: 11332561.
    Citations:    Fields:    Translation:Humans
  56. Klingenheben T, Zabel M, D'Agostino RB, Cohen RJ, Hohnloser SH. Predictive value of T-wave alternans for arrhythmic events in patients with congestive heart failure. Lancet. 2000 Aug 19; 356(9230):651-2. PMID: 10968440.
    Citations: 33     Fields:    Translation:HumansCTClinical Trials
  57. Armoundas AA, Nanke T, Cohen RJ. Images in cardiovascular medicine. T-wave alternans preceding torsade de pointes ventricular tachycardia. Circulation. 2000 May 30; 101(21):2550. PMID: 10831532.
    Citations: 6     Fields:    Translation:Humans
  58. Mukkamala R, Cohen RJ. A noninvasive method for total peripheral resistance baroreflex identification. Comput Cardiol. 2000; 27:53-6. PMID: 14632006.
    Citations:    Translation:Humans
  59. Fukuoka Y, Armoundas AA, Oostendorp TF, Cohen RJ. Accuracy of a single equivalent moving dipole model in a realistic anatomic geometry torso model. Comput Cardiol. 2000; 27:439-42. PMID: 14632014.
    Citations: 1     Translation:Humans
  60. Aljuri A, Marini RP, Cohen RJ. A conscious sheep model for the examination of arterial and cardiopulmonary baroreceptors in the dynamic closed-loop control of Total Peripheral Resistance. Comput Cardiol. 2000; 27:41-4. PMID: 14632005.
    Citations:    Translation:AnimalsCells
  61. Bursac N, Papadaki M, Cohen RJ, Schoen FJ, Eisenberg SR, Carrier R, Vunjak-Novakovic G, Freed LE. Cardiac muscle tissue engineering: toward an in vitro model for electrophysiological studies. Am J Physiol. 1999 08; 277(2):H433-44. PMID: 10444466.
    Citations: 80     Fields:    Translation:AnimalsPHPublic Health
  62. Hohnloser S, Cohen RJ. T wave alternans and left ventricular ejection fraction, but not QT variability index, predict appropriate ICD discharge. J Cardiovasc Electrophysiol. 1999 Apr; 10(4):626-7. PMID: 10355708.
    Citations: 1     Fields:    Translation:Humans
  63. Mukkamala R, Mathias JM, Mullen TJ, Cohen RJ, Freeman R. System identification of closed-loop cardiovascular control mechanisms: diabetic autonomic neuropathy. Am J Physiol. 1999 Mar; 276(3 Pt 2):R905-12. PMID: 10070154.
    Citations: 10     Fields:    Translation:Humans
  64. Hohnloser SH, Klingenheben T, Li YG, Zabel M, Peetermans J, Cohen RJ. T wave alternans as a predictor of recurrent ventricular tachyarrhythmias in ICD recipients: prospective comparison with conventional risk markers. J Cardiovasc Electrophysiol. 1998 Dec; 9(12):1258-68. PMID: 9869525.
    Citations: 13     Fields:    Translation:Humans
  65. Armoundas AA, Osaka M, Mela T, Rosenbaum DS, Ruskin JN, Garan H, Cohen RJ. T-wave alternans and dispersion of the QT interval as risk stratification markers in patients susceptible to sustained ventricular arrhythmias. Am J Cardiol. 1998 Nov 01; 82(9):1127-9, A9. PMID: 9817496.
    Citations: 5     Fields:    Translation:Humans
  66. Armoundas AA, Rosenbaum DS, Ruskin JN, Garan H, Cohen RJ. Prognostic significance of electrical alternans versus signal averaged electrocardiography in predicting the outcome of electrophysiological testing and arrhythmia-free survival. Heart. 1998 Sep; 80(3):251-6. PMID: 9875084.
    Citations: 5     Fields:    Translation:Humans
  67. Feldman AB, Chernyak YB, Cohen RJ. Spiral waves are stable in discrete element models of two-dimensional homogeneous excitable media. Int J Bifurcat Chaos. 1998 Jun; 8(6):1153-61. PMID: 11542661.
    Citations: 1     
  68. Mullen TJ, Berger RD, Oman CM, Cohen RJ. Human heart rate variability relation is unchanged during motion sickness. J Vestib Res. 1998 Jan-Feb; 8(1):95-105. PMID: 9416595.
    Citations: 6     Fields:    Translation:Humans
  69. Osaka M, Saitoh H, Yokoshima T, Kishida H, Hayakawa H, Cohen RJ. Nonlinear pattern analysis of ventricular premature beats by mutual information. Methods Inf Med. 1997 Dec; 36(4-5):257-60. PMID: 9470372.
    Citations:    Fields:    Translation:Humans
  70. Chon KH, Kanters JK, Cohen RJ, Holstein-Rathlou NH. Detection of "noisy" chaos in a time series. Methods Inf Med. 1997 Dec; 36(4-5):294-7. PMID: 9470382.
    Citations:    Fields:    
  71. Estes NA, Michaud G, Zipes DP, El-Sherif N, Venditti FJ, Rosenbaum DS, Albrecht P, Wang PJ, Cohen RJ. Electrical alternans during rest and exercise as predictors of vulnerability to ventricular arrhythmias. Am J Cardiol. 1997 Nov 15; 80(10):1314-8. PMID: 9388105.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  72. Chon KH, Mukkamala R, Toska K, Mullen TJ, Armoundas AA, Cohen RJ. Linear and nonlinear system identification of autonomic heart-rate modulation. IEEE Eng Med Biol Mag. 1997 Sep-Oct; 16(5):96-105. PMID: 9313086.
    Citations: 3     Fields:    Translation:Humans
  73. Hohnloser SH, Klingenheben T, Zabel M, Li YG, Albrecht P, Cohen RJ. T wave alternans during exercise and atrial pacing in humans. J Cardiovasc Electrophysiol. 1997 Sep; 8(9):987-93. PMID: 9300295.
    Citations: 17     Fields:    Translation:Humans
  74. Raeder EA, Stys A, Cohen RJ. Effect of low-dose scopolamine on autonomic control of the heart. Ann Noninvasive Electrocardiol. 1997 Jul; 2(3):236-41. PMID: 11541512.
    Citations: 1     Fields:    Translation:Humans
  75. Chon KH, Cohen RJ, Holstein-Rathlou NH. Compact and accurate linear and nonlinear autoregressive moving average model parameter estimation using laguerre functions. Ann Biomed Eng. 1997 Jul-Aug; 25(4):731-8. PMID: 9236985.
    Citations: 1     Fields:    
  76. Chernyak YB, Feldman AB, Cohen RJ. Correspondence between discrete and continuous models of excitable media: trigger waves. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 1997 Mar; 55(3 Pt B):3215-33. PMID: 11540551.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  77. Chon KH, Cohen RJ. Linear and nonlinear ARMA model parameter estimation using an artificial neural network. IEEE Trans Biomed Eng. 1997 Mar; 44(3):168-74. PMID: 9216130.
    Citations:    Fields:    Translation:Humans
  78. Mullen TJ, Appel ML, Mukkamala R, Mathias JM, Cohen RJ. System identification of closed-loop cardiovascular control: effects of posture and autonomic blockade. Am J Physiol. 1997 Jan; 272(1 Pt 2):H448-61. PMID: 9038967.
    Citations: 15     Fields:    Translation:Humans
  79. Armoundas AA, Cohen RJ. Clinical utility of T-wave alternans. Card Electrophysiol Rev. 1997; 1(3):390-4. PMID: 11541510.
    Citations: 4     Fields:    Translation:HumansAnimals
  80. Chon KH, Kanters JK, Cohen RJ, Holstein-Rathlou NH. Detection of chaotic determinism in time series from randomly forced maps. Physica D. 1997; 99:471-86. PMID: 11540720.
    Citations: 2     Translation:Humans
  81. Rosenbaum DS, Albrecht P, Cohen RJ. Predicting sudden cardiac death from T wave alternans of the surface electrocardiogram: promise and pitfalls. J Cardiovasc Electrophysiol. 1996 Nov; 7(11):1095-111. PMID: 8930743.
    Citations: 12     Fields:    Translation:Humans
  82. Bigger JT, Steinman RC, Rolnitzky LM, Fleiss JL, Albrecht P, Cohen RJ. Power law behavior of RR-interval variability in healthy middle-aged persons, patients with recent acute myocardial infarction, and patients with heart transplants. Circulation. 1996 Jun 15; 93(12):2142-51. PMID: 8925583.
    Citations: 57     Fields:    Translation:Humans
  83. Chon KH, Mullen TJ, Cohen RJ. A dual-input nonlinear system analysis of autonomic modulation of heart rate. IEEE Trans Biomed Eng. 1996 May; 43(5):530-44. PMID: 8849465.
    Citations: 12     Fields:    Translation:Humans
  84. Perrott MH, Cohen RJ. An efficient approach to ARMA modeling of biological systems with multiple inputs and delays. IEEE Trans Biomed Eng. 1996 Jan; 43(1):1-14. PMID: 8567000.
    Citations: 3     Fields:    
  85. Osaka M, Saitoh H, Sasabe N, Atarashi H, Katoh T, Hayakawa H, Cohen RJ. Changes in autonomic activity preceding onset of nonsustained ventricular tachycardia. Ann Noninvasive Electrocardiol. 1996 Jan; 1(1):3-11. PMID: 11540719.
    Citations: 3     Fields:    Translation:Humans
  86. Albrecht P, Arnold J, Krishnamachari S, Cohen RJ. Exercise recordings for the detection of T wave alternans. Promises and pitfalls. J Electrocardiol. 1996; 29 Suppl:46-51. PMID: 9238377.
    Citations: 2     Fields:    Translation:Humans
  87. Sykulev Y, Cohen RJ, Eisen HN. The law of mass action governs antigen-stimulated cytolytic activity of CD8+ cytotoxic T lymphocytes. Proc Natl Acad Sci U S A. 1995 Dec 19; 92(26):11990-2. PMID: 8618829.
    Citations: 30     Fields:    Translation:AnimalsCells
  88. He B, Chernyak YB, Cohen RJ. An equivalent body surface charge model representing three-dimensional bioelectrical activity. IEEE Trans Biomed Eng. 1995 Jul; 42(7):637-46. PMID: 7622147.
    Citations: 2     Fields:    Translation:Humans
  89. Osaka M, Chon KH, Cohen RJ. Distinguishing cardiac randomness from chaos. J Cardiovasc Electrophysiol. 1995 Jun; 6(6):441-2. PMID: 7551313.
    Citations: 2     Fields:    Translation:Humans
  90. Raeder EA, Albrecht P, Perrott M, Cohen RJ. Kinetics of cycle length dependence of ventricular repolarization: effect of autonomic blockade. J Cardiovasc Electrophysiol. 1995 Mar; 6(3):163-9. PMID: 7620641.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  91. He B, Cohen RJ. Body surface Laplacian electrocardiographic mapping--a review. Crit Rev Biomed Eng. 1995; 23(5-6):475-510. PMID: 9017346.
    Citations: 3     Fields:    Translation:HumansAnimals
  92. Sykulev Y, Brunmark A, Jackson M, Cohen RJ, Peterson PA, Eisen HN. Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes. Immunity. 1994 Apr; 1(1):15-22. PMID: 7889394.
    Citations: 65     Fields:    Translation:HumansCells
  93. Rosenbaum DS, Jackson LE, Smith JM, Garan H, Ruskin JN, Cohen RJ. Electrical alternans and vulnerability to ventricular arrhythmias. N Engl J Med. 1994 Jan 27; 330(4):235-41. PMID: 8272084.
    Citations: 152     Fields:    Translation:Humans
  94. Leffler CT, Saul JP, Cohen RJ. Rate-related and autonomic effects on atrioventricular conduction assessed through beat-to-beat PR interval and cycle length variability. J Cardiovasc Electrophysiol. 1994 Jan; 5(1):2-15. PMID: 8186873.
    Citations: 4     Fields:    Translation:Humans
  95. He B, Kirby DA, Mullen TJ, Cohen RJ. Body surface Laplacian mapping of cardiac excitation in intact pigs. Pacing Clin Electrophysiol. 1993 May; 16(5 Pt 1):1017-26. PMID: 7685881.
    Citations: 2     Fields:    Translation:Animals
  96. Berger RD, Rosenbaum DS, Cohen RJ. Is the power spectrum of the QRS complex related to a fractal His-Purkinje system? Am J Cardiol. 1993 Feb 15; 71(5):430-3. PMID: 7679243.
    Citations: 1     Fields:    Translation:Humans
  97. Sykulev YK, Cohen RJ, Eisen HN. Particle counting by flow cytometry can determine intrinsic equilibrium constants for antibody-ligand interactions in solution. Mol Immunol. 1993 Jan; 30(1):101-4. PMID: 8417367.
    Citations:    Fields:    
  98. Yana K, Saul JP, Berger RD, Perrott MH, Cohen RJ. A time domain approach for the fluctuation analysis of heart rate related to instantaneous lung volume. IEEE Trans Biomed Eng. 1993 Jan; 40(1):74-81. PMID: 8468078.
    Citations: 4     Fields:    Translation:Humans
  99. He B, Cohen RJ. Body surface Laplacian mapping of cardiac electrical activity. Am J Cardiol. 1992 Dec 15; 70(20):1617-20. PMID: 1466337.
    Citations: 3     Fields:    Translation:Humans
  100. He B, Cohen RJ. Body surface Laplacian ECG mapping. IEEE Trans Biomed Eng. 1992 Nov; 39(11):1179-91. PMID: 1487281.
    Citations: 5     Fields:    Translation:Humans
  101. Sykulev YK, Sherman DA, Cohen RJ, Eisen HN. Quantitation of reversible binding by particle counting: hapten-antibody interaction as a model system. Proc Natl Acad Sci U S A. 1992 May 15; 89(10):4703-7. PMID: 1584807.
    Citations: 1     Fields:    
  102. Saul JP, Berger RD, Albrecht P, Stein SP, Chen MH, Cohen RJ. Transfer function analysis of the circulation: unique insights into cardiovascular regulation. Am J Physiol. 1991 Oct; 261(4 Pt 2):H1231-45. PMID: 1928405.
    Citations: 95     Fields:    Translation:Humans
  103. Rosenbaum DS, Kaplan DT, Kanai A, Jackson L, Garan H, Cohen RJ, Salama G. Repolarization inhomogeneities in ventricular myocardium change dynamically with abrupt cycle length shortening. Circulation. 1991 Sep; 84(3):1333-45. PMID: 1884456.
    Citations: 9     Fields:    Translation:Animals
  104. Clancy EA, Smith JM, Cohen RJ. A simple electrical-mechanical model of the heart applied to the study of electrical-mechanical alternans. IEEE Trans Biomed Eng. 1991 Jun; 38(6):551-60. PMID: 1879844.
    Citations: 4     Fields:    Translation:HumansAnimals
  105. Madwed JB, Cohen RJ. Heart rate response to hemorrhage-induced 0.05-Hz oscillations in arterial pressure in conscious dogs. Am J Physiol. 1991 Apr; 260(4 Pt 2):H1248-53. PMID: 1849372.
    Citations: 4     Fields:    Translation:Animals
  106. Abboud S, Cohen RJ, Sadeh D. A spectral analysis of the high frequency QRS potentials observed during acute myocardial ischemia in dogs. Int J Cardiol. 1990 Mar; 26(3):285-90. PMID: 2312198.
    Citations: 3     Fields:    Translation:Animals
  107. Saul JP, Rea RF, Eckberg DL, Berger RD, Cohen RJ. Heart rate and muscle sympathetic nerve variability during reflex changes of autonomic activity. Am J Physiol. 1990 Mar; 258(3 Pt 2):H713-21. PMID: 2316686.
    Citations: 41     Fields:    Translation:Humans
  108. Kaplan DT, Cohen RJ. Searching for chaos in fibrillation. Ann N Y Acad Sci. 1990; 591:367-74. PMID: 2197929.
    Citations: 4     Fields:    Translation:Animals
  109. Saxberg BE, Cohen RJ. Cellular automata models for reentrant arrhythmias. J Electrocardiol. 1990; 23 Suppl:95. PMID: 2090766.
    Citations: 1     Fields:    Translation:Humans
  110. Appel ML, Berger RD, Saul JP, Smith JM, Cohen RJ. Beat to beat variability in cardiovascular variables: noise or music? J Am Coll Cardiol. 1989 Nov 01; 14(5):1139-48. PMID: 2681319.
    Citations: 87     Fields:    Translation:Humans
  111. Bigger JT, Albrecht P, Steinman RC, Rolnitzky LM, Fleiss JL, Cohen RJ. Comparison of time- and frequency domain-based measures of cardiac parasympathetic activity in Holter recordings after myocardial infarction. Am J Cardiol. 1989 Sep 01; 64(8):536-8. PMID: 2773799.
    Citations: 13     Fields:    Translation:Humans
  112. Madwed JB, Albrecht P, Mark RG, Cohen RJ. Low-frequency oscillations in arterial pressure and heart rate: a simple computer model. Am J Physiol. 1989 Jun; 256(6 Pt 2):H1573-9. PMID: 2735430.
    Citations: 28     Fields:    Translation:Animals
  113. Berger RD, Saul JP, Cohen RJ. Transfer function analysis of autonomic regulation. I. Canine atrial rate response. Am J Physiol. 1989 Jan; 256(1 Pt 2):H142-52. PMID: 2912176.
    Citations: 72     Fields:    Translation:Animals
  114. Saul JP, Berger RD, Chen MH, Cohen RJ. Transfer function analysis of autonomic regulation. II. Respiratory sinus arrhythmia. Am J Physiol. 1989 Jan; 256(1 Pt 2):H153-61. PMID: 2912177.
    Citations: 37     Fields:    Translation:Humans
  115. Sands KE, Appel ML, Lilly LS, Schoen FJ, Mudge GH, Cohen RJ. Power spectrum analysis of heart rate variability in human cardiac transplant recipients. Circulation. 1989 Jan; 79(1):76-82. PMID: 2642758.
    Citations: 23     Fields:    Translation:Humans
  116. Arai Y, Saul JP, Albrecht P, Hartley LH, Lilly LS, Cohen RJ, Colucci WS. Modulation of cardiac autonomic activity during and immediately after exercise. Am J Physiol. 1989 Jan; 256(1 Pt 2):H132-41. PMID: 2643348.
    Citations: 98     Fields:    Translation:Humans
  117. Albrecht P, Cohen RJ, Mark RG. A stochastic characterization of chronic ventricular ectopic activity. IEEE Trans Biomed Eng. 1988 Jul; 35(7):539-50. PMID: 3209215.
    Citations: 2     Fields:    Translation:Humans
  118. Saul JP, Arai Y, Berger RD, Lilly LS, Colucci WS, Cohen RJ. Assessment of autonomic regulation in chronic congestive heart failure by heart rate spectral analysis. Am J Cardiol. 1988 Jun 01; 61(15):1292-9. PMID: 3376889.
    Citations: 82     Fields:    Translation:Humans
  119. Kaplan DT, Smith JM, Saxberg BE, Cohen RJ. Nonlinear dynamics in cardiac conduction. Math Biosci. 1988; 90:19-48. PMID: 11539069.
    Citations: 9     Fields:    Translation:HumansAnimals
  120. Smith JM, Rosenbaum DS, Cohen RJ. Variability in surface ECG morphology: signal or noise? Comput Cardiol. 1988; 14:257-60. PMID: 11542155.
    Citations: 1     Translation:Animals
  121. Saul JP, Albrecht P, Berger RD, Cohen RJ. Analysis of long term heart rate variability: methods, 1/f scaling and implications. Comput Cardiol. 1988; 14:419-22. PMID: 11542156.
    Citations: 31     Translation:Humans
  122. Kaplan DT, Smith JM, Rosenbaum DS, Cohen RJ. On the precision of automated activation time estimation. Comput Cardiol. 1988; 14:101-4. PMID: 11542154.
    Citations: 1     Translation:Animals
  123. Smith JM, Clancy EA, Valeri CR, Ruskin JN, Cohen RJ. Electrical alternans and cardiac electrical instability. Circulation. 1988 Jan; 77(1):110-21. PMID: 3335062.
    Citations: 48     Fields:    Translation:HumansAnimals
  124. Sadeh D, Shannon DC, Abboud S, Saul JP, Akselrod S, Cohen RJ. Altered cardiac repolarization in some victims of sudden infant death syndrome. N Engl J Med. 1987 Dec 10; 317(24):1501-5. PMID: 3683486.
    Citations: 7     Fields:    Translation:Humans
  125. Saxberg BE, Cohen RJ. Applications of a detailed model of cardiac conduction to ventricular dysrhythmogenesis. Comput Cardiol. 1987; 13:207-10. PMID: 11541827.
    Citations:    Translation:Humans
  126. Chen MH, Berger RD, Saul JP, Stevenson K, Cohen RJ. Transfer function analysis of the autonomic response to respiratory activity during random interval breathing. Comput Cardiol. 1987; 13:149-52. PMID: 11541826.
    Citations:    Translation:Humans
  127. Grumbach MP, Saxberg BE, Cohen RJ. Computer simulation of fibrillation threshold measurements and electrophysiologic testing procedures. Comput Cardiol. 1987; 13:449-52. PMID: 11541829.
    Citations:    
  128. Sadeh D, Shannon DC, Abboud S, Akselrod S, Cohen RJ. A new technique to determine the correlation between the QT interval and heart-rate for control and SIDS babies. Comput Cardiol. 1987; 13:125-7. PMID: 11541825.
    Citations: 1     Translation:Humans
  129. Abboud S, Blatt CM, Lown B, Graboys TB, Sadeh D, Cohen RJ. Signal averaging technique for noninvasive recording of late potentials in patients with coronary artery disease. Comput Cardiol. 1987; 13:525-8. PMID: 11541830.
    Citations:    Translation:Humans
  130. Kaplan DT, Cohen RJ. Application of non-linear dynamics to the characterization of cardiac electrical instability. Comput Cardiol. 1987; 13:439-42. PMID: 11541828.
    Citations:    Translation:Animals
  131. Berger RD, Akselrod S, Gordon D, Cohen RJ. An efficient algorithm for spectral analysis of heart rate variability. IEEE Trans Biomed Eng. 1986 Sep; 33(9):900-4. PMID: 3759126.
    Citations: 94     Fields:    Translation:Humans
  132. Saxberg BE, Grumbach MP, Cohen RJ. A time dependent anatomically detailed model of cardiac conduction. Comput Cardiol. 1985; 12:401-4. PMID: 11542765.
    Citations:    Translation:Humans
  133. Smith JM, Blue B, Clancy E, Valeri CR, Cohen RJ. Subtle alternating electrocardiographic morphology as an indicator of decreased cardiac electrical stability. Comput Cardiol. 1985; 12:109-12. PMID: 11542763.
    Citations: 2     Translation:Animals
  134. Smith JM, Cohen RJ. Simple finite-element model accounts for wide range of cardiac dysrhythmias. Proc Natl Acad Sci U S A. 1984 Jan; 81(1):233-7. PMID: 6582478.
    Citations: 14     Fields:    Translation:HumansAnimals
  135. Akselrod S, Gordon D, Ubel FA, Shannon DC, Berger AC, Cohen RJ. Power spectrum analysis of heart rate fluctuation: a quantitative probe of beat-to-beat cardiovascular control. Science. 1981 Jul 10; 213(4504):220-2. PMID: 6166045.
    Citations: 576     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.