Harvard Catalyst Profiles

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Christiane Ferran, PH.D., M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21EB024308 (FERRAN, CHRISTIANE) Apr 1, 2018 - Jan 31, 2020
    NIH/NIBIB
    Bioengineering of vein grafts to resist intimal hyperplasia
    Role: Principal Investigator
  2. R21DK091822 (FERRAN, CHRISTIANE) Sep 1, 2011 - Aug 31, 2014
    NIH/NIDDK
    A20 Gene Polymorphisms in LDLT
    Role: Principal Investigator
  3. R01HL086741 (LOGERFO, FRANK W) Feb 1, 2007 - Dec 31, 2022
    NIH/NHLBI
    Genetic Engineering of Vein Bypass Grafts in Vascular and Cardiovascular Surgery
    Role: Co-Principal Investigator
  4. R01HL080130 (FERRAN, CHRISTIANE) Jun 15, 2006 - May 31, 2013
    NIH/NHLBI
    Vascular Remodeling in Transplant Arteriosclerosis
    Role: Principal Investigator
  5. R01DK063275 (FERRAN, CHRISTIANE) Jan 1, 2003 - May 31, 2014
    NIH/NIDDK
    Improved liver function and regeneration with A20
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Moll HP, Lee A, Peterson CR, Revuelta Cervantes J, Wojcik BM, Parulkar A, Mele A, LoGerfo PJ, Siracuse JJ, Csizmadia E, da Silva CG, Ferran C. A20 Haploinsufficiency Aggravates Transplant Arteriosclerosis in Mouse Vascular Allografts: Implications for Clinical Transplantation. Transplantation. 2016 Nov; 100(11):e106-e116. PMID: 27495763.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  2. Studer P, da Silva CG, Revuelta Cervantes JM, Mele A, Csizmadia E, Siracuse JJ, Damrauer SM, Peterson CR, Candinas D, Stroka DM, Ma A, Bhasin M, Ferran C. Significant lethality following liver resection in A20 heterozygous knockout mice uncovers a key role for A20 in liver regeneration. Cell Death Differ. 2015 Dec; 22(12):2068-77. PMID: 25976305.
    Citations: 6     Fields:    Translation:AnimalsCells
  3. Enesa K, Moll HP, Luong L, Ferran C, Evans PC. A20 suppresses vascular inflammation by recruiting proinflammatory signaling molecules to intracellular aggresomes. FASEB J. 2015 May; 29(5):1869-78. PMID: 25667218.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  4. Pathan SG, Fitzgerald LM, Ali SM, Damrauer SM, Bide MJ, Nelson DW, Ferran C, Phaneuf TM, Phaneuf MD. Cytotoxicity associated with electrospun polyvinyl alcohol. J Biomed Mater Res B Appl Biomater. 2015 Nov; 103(8):1652-62. PMID: 25573200.
    Citations: 2     Fields:    Translation:HumansCells
  5. Moll HP, Lee A, Minussi DC, da Silva CG, Csizmadia E, Bhasin M, Ferran C. A20 regulates atherogenic interferon (IFN)-? signaling in vascular cells by modulating basal IFNß levels. J Biol Chem. 2014 Nov 07; 289(45):30912-24. PMID: 25217635.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  6. Guedes RP, Csizmadia E, Moll HP, Ma A, Ferran C, da Silva CG. A20 deficiency causes spontaneous neuroinflammation in mice. J Neuroinflammation. 2014 Jul 16; 11:122. PMID: 25026958.
    Citations: 13     Fields:    Translation:AnimalsCells
  7. Vissapragada R, Contreras MA, da Silva CG, Kumar VA, Ochoa A, Vasudevan A, Selim MH, Ferran C, Thomas AJ. Bidirectional crosstalk between periventricular endothelial cells and neural progenitor cells promotes the formation of a neurovascular unit. Brain Res. 2014 May 27; 1565:8-17. PMID: 24675025.
    Citations: 6     Fields:    Translation:AnimalsCells
  8. Mele A, Cervantes JR, Chien V, Friedman D, Ferran C. Single nucleotide polymorphisms at the TNFAIP3/A20 locus and susceptibility/resistance to inflammatory and autoimmune diseases. Adv Exp Med Biol. 2014; 809:163-83. PMID: 25302371.
    Citations: 10     Fields:    Translation:HumansAnimals
  9. da Silva CG, Cervantes JR, Studer P, Ferran C. A20--an omnipotent protein in the liver: prometheus myth resolved? Adv Exp Med Biol. 2014; 809:117-39. PMID: 25302369.
    Citations: 5     Fields:    Translation:HumansAnimals
  10. Arguello M, Paz S, Ferran C, Moll HP, Hiscott J. Anti-viral tetris: modulation of the innate anti-viral immune response by A20. Adv Exp Med Biol. 2014; 809:49-64. PMID: 25302365.
    Citations: 2     Fields:    Translation:HumansCells
  11. da Silva CG, Minussi DC, Ferran C, Bredel M. A20 expressing tumors and anticancer drug resistance. Adv Exp Med Biol. 2014; 809:65-81. PMID: 25302366.
    Citations: 4     Fields:    Translation:Humans
  12. Ferran C. Preface. The multiple therapeutic targets of A20. Adv Exp Med Biol. 2014; 809:ix-x. PMID: 25302361.
    Citations: 1     Fields:    Translation:HumansAnimals
  13. McGillicuddy FC, Moll HP, Farouk S, Damrauer SM, Ferran C, Reilly MP. Translational studies of A20 in atherosclerosis and cardiovascular disease. Adv Exp Med Biol. 2014; 809:83-101. PMID: 25302367.
    Citations: 5     Fields:    Translation:HumansAnimals
  14. Kaczmarek E, Bakker JP, Clarke DN, Csizmadia E, Kocher O, Veves A, Tecilazich F, O'Donnell CP, Ferran C, Malhotra A. Molecular biomarkers of vascular dysfunction in obstructive sleep apnea. PLoS One. 2013; 8(7):e70559. PMID: 23923005.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  15. da Silva CG, Studer P, Skroch M, Mahiou J, Minussi DC, Peterson CR, Wilson SW, Patel VI, Ma A, Csizmadia E, Ferran C. A20 promotes liver regeneration by decreasing SOCS3 expression to enhance IL-6/STAT3 proliferative signals. Hepatology. 2013 May; 57(5):2014-25. PMID: 23238769.
    Citations: 24     Fields:    Translation:AnimalsCells
  16. Guedes RP, Rocha E, Mahiou J, Moll HP, Arvelo MB, Taube JM, Peterson CR, Kaczmarek E, Longo CR, da Silva CG, Ferran C. The C-terminal domain of A1/Bfl-1 regulates its anti-inflammatory function in human endothelial cells. Biochim Biophys Acta. 2013 Jun; 1833(6):1553-61. PMID: 23499873.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  17. Bhasin M, Huang Z, Pradhan-Nabzdyk L, Malek JY, LoGerfo PJ, Contreras M, Guthrie P, Csizmadia E, Andersen N, Kocher O, Ferran C, LoGerfo FW. Temporal network based analysis of cell specific vein graft transcriptome defines key pathways and hub genes in implantation injury. PLoS One. 2012; 7(6):e39123. PMID: 22720046.
    Citations: 13     Fields:    Translation:AnimalsCells
  18. da Silva CG, Maccariello ER, Wilson SW, Putheti P, Daniel S, Damrauer SM, Peterson CR, Siracuse JJ, Kaczmarek E, Ferran C. Hepatocyte growth factor preferentially activates the anti-inflammatory arm of NF-?B signaling to induce A20 and protect renal proximal tubular epithelial cells from inflammation. J Cell Physiol. 2012 Apr; 227(4):1382-90. PMID: 21618526.
    Citations: 7     Fields:    Translation:HumansCells
  19. Siracuse JJ, Fisher MD, da Silva CG, Peterson CR, Csizmadia E, Moll HP, Damrauer SM, Studer P, Choi LY, Essayagh S, Kaczmarek E, Maccariello ER, Lee A, Daniel S, Ferran C. A20-mediated modulation of inflammatory and immune responses in aortic allografts and development of transplant arteriosclerosis. Transplantation. 2012 Feb 27; 93(4):373-82. PMID: 22245872.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  20. Wang H, Ferran C, Attanasio C, Calise F, Otterbein LE. Induction of protective genes leads to islet survival and function. J Transplant. 2011; 2011:141898. PMID: 22220267.
    Citations: 7     
  21. Damrauer SM, Studer P, da Silva CG, Longo CR, Ramsey HE, Csizmadia E, Shrikhande GV, Scali ST, Libermann TA, Bhasin MK, Ferran C. A20 modulates lipid metabolism and energy production to promote liver regeneration. PLoS One. 2011 Mar 17; 6(3):e17715. PMID: 21437236.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  22. Shrikhande GV, Scali ST, da Silva CG, Damrauer SM, Csizmadia E, Putheti P, Matthey M, Arjoon R, Patel R, Siracuse JJ, Maccariello ER, Andersen ND, Monahan T, Peterson C, Essayagh S, Studer P, Guedes RP, Kocher O, Usheva A, Veves A, Kaczmarek E, Ferran C. O-glycosylation regulates ubiquitination and degradation of the anti-inflammatory protein A20 to accelerate atherosclerosis in diabetic ApoE-null mice. PLoS One. 2010 Dec 06; 5(12):e14240. PMID: 21151899.
    Citations: 23     Fields:    Translation:AnimalsCells
  23. Andersen ND, Chopra A, Monahan TS, Malek JY, Jain M, Pradhan L, Ferran C, LoGerfo FW. Endothelial cells are susceptible to rapid siRNA transfection and gene silencing ex vivo. J Vasc Surg. 2010 Dec; 52(6):1608-15. PMID: 20801607.
    Citations: 3     Fields:    Translation:Humans
  24. Feng J, Damrauer SM, Lee M, Sellke FW, Ferran C, Abid MR. Endothelium-dependent coronary vasodilatation requires NADPH oxidase-derived reactive oxygen species. Arterioscler Thromb Vasc Biol. 2010 Sep; 30(9):1703-10. PMID: 20702812.
    Citations: 24     Fields:    Translation:AnimalsCells
  25. Damrauer SM, Fisher MD, Wada H, Siracuse JJ, da Silva CG, Moon K, Csizmadia E, Maccariello ER, Patel VI, Studer P, Essayagh S, Aird WC, Daniel S, Ferran C. A20 inhibits post-angioplasty restenosis by blocking macrophage trafficking and decreasing adventitial neovascularization. Atherosclerosis. 2010 Aug; 211(2):404-8. PMID: 20430393.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  26. Ramsey HE, Da Silva CG, Longo CR, Csizmadia E, Studer P, Patel VI, Damrauer SM, Siracuse JJ, Daniel S, Ferran C. A20 protects mice from lethal liver ischemia/reperfusion injury by increasing peroxisome proliferator-activated receptor-alpha expression. Liver Transpl. 2009 Nov; 15(11):1613-21. PMID: 19877201.
    Citations: 14     Fields:    Translation:AnimalsCells
  27. Tran TM, Temkin V, Shi B, Pagliari L, Daniel S, Ferran C, Pope RM. TNFalpha-induced macrophage death via caspase-dependent and independent pathways. Apoptosis. 2009 Mar; 14(3):320-32. PMID: 19152111.
    Citations: 14     Fields:    Translation:HumansCells
  28. da Silva CG, Specht A, Wegiel B, Ferran C, Kaczmarek E. Mechanism of purinergic activation of endothelial nitric oxide synthase in endothelial cells. Circulation. 2009 Feb 17; 119(6):871-9. PMID: 19188511.
    Citations: 30     Fields:    Translation:HumansCells
  29. Monahan TS, Andersen ND, Martin MC, Malek JY, Shrikhande GV, Pradhan L, Ferran C, LoGerfo FW. MARCKS silencing differentially affects human vascular smooth muscle and endothelial cell phenotypes to inhibit neointimal hyperplasia in saphenous vein. FASEB J. 2009 Feb; 23(2):557-64. PMID: 18940893.
    Citations: 17     Fields:    Translation:HumansCells
  30. Monahan TS, Andersen ND, Panossian H, Kalish JA, Daniel S, Shrikhande GV, Ferran C, Logerfo FW. A novel function for cadherin 11/osteoblast-cadherin in vascular smooth muscle cells: modulation of cell migration and proliferation. J Vasc Surg. 2007 Mar; 45(3):581-9. PMID: 17321345.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  31. Andersen ND, Monahan TS, Malek JY, Jain M, Daniel S, Caron LD, Pradhan L, Ferran C, Logerfo FW. Comparison of gene silencing in human vascular cells using small interfering RNAs. J Am Coll Surg. 2007 Mar; 204(3):399-408. PMID: 17324773.
    Citations: 10     Fields:    Translation:HumansCells
  32. Daniel S, Patel VI, Shrikhande GV, Scali ST, Ramsey HE, Csizmadia E, Benhaga N, Fisher MD, Arvelo MB, Ferran C. The universal NF-kappaB inhibitor a20 protects from transplant vasculopathy by differentially affecting apoptosis in endothelial and smooth muscle cells. Transplant Proc. 2006 Dec; 38(10):3225-7. PMID: 17175229.
    Citations: 9     Fields:    Translation:Animals
  33. Ferran C. Protective genes in the vessel wall: Modulators of graft survival and function. Transplantation. 2006 Jul 15; 82(1 Suppl):S36-40. PMID: 16829794.
    Citations: 6     Fields:    Translation:Animals
  34. Patel VI, Daniel S, Longo CR, Shrikhande GV, Scali ST, Czismadia E, Groft CM, Shukri T, Motley-Dore C, Ramsey HE, Fisher MD, Grey ST, Arvelo MB, Ferran C. A20, a modulator of smooth muscle cell proliferation and apoptosis, prevents and induces regression of neointimal hyperplasia. FASEB J. 2006 Jul; 20(9):1418-30. PMID: 16816117.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  35. Shrikhande G, Khaodhiar L, Scali S, Lima C, Hubbard M, Dudley K, Ganda O, Ferran C, Veves A. Valsartan improves resting skin blood flow in type 2 diabetic patients and reduces poly(adenosine diphosphate-ribose) polymerase activation. J Vasc Surg. 2006 Apr; 43(4):760-70; discussion 770-1. PMID: 16616233.
    Citations: 5     Fields:    Translation:Humans
  36. Kunter U, Daniel S, Arvelo MB, Choi J, Shukri T, Patel VI, Longo CR, Scali ST, Shrikhande G, Rocha E, Czismadia E, Mottley C, Grey ST, Floege J, Ferran C. Combined expression of A1 and A20 achieves optimal protection of renal proximal tubular epithelial cells. Kidney Int. 2005 Oct; 68(4):1520-32. PMID: 16164629.
    Citations: 13     Fields:    Translation:HumansCells
  37. Longo CR, Patel VI, Shrikhande GV, Scali ST, Csizmadia E, Daniel S, Sun DW, Grey ST, Arvelo MB, Ferran C. A20 protects mice from lethal radical hepatectomy by promoting hepatocyte proliferation via a p21waf1-dependent mechanism. Hepatology. 2005 Jul; 42(1):156-64. PMID: 15962316.
    Citations: 18     Fields:    Translation:AnimalsCells
  38. Abid MR, Yano K, Guo S, Patel VI, Shrikhande G, Spokes KC, Ferran C, Aird WC. Forkhead transcription factors inhibit vascular smooth muscle cell proliferation and neointimal hyperplasia. J Biol Chem. 2005 Aug 19; 280(33):29864-73. PMID: 15961397.
    Citations: 40     Fields:    Translation:HumansAnimalsCells
  39. Avihingsanon Y, Ma N, Pavlakis M, Chon WJ, Uknis ME, Monaco AP, Ferran C, Stillman I, Schachter AD, Mottley C, Zheng XX, Strom TB. On the intraoperative molecular status of renal allografts after vascular reperfusion and clinical outcomes. J Am Soc Nephrol. 2005 Jun; 16(6):1542-8. PMID: 15888558.
    Citations: 13     Fields:    Translation:Humans
  40. Storz P, Döppler H, Ferran C, Grey ST, Toker A. Functional dichotomy of A20 in apoptotic and necrotic cell death. Biochem J. 2005 Apr 01; 387(Pt 1):47-55. PMID: 15527421.
    Citations: 13     Fields:    Translation:HumansCells
  41. Song R, Zhou Z, Kim PK, Shapiro RA, Liu F, Ferran C, Choi AM, Otterbein LE. Carbon monoxide promotes Fas/CD95-induced apoptosis in Jurkat cells. J Biol Chem. 2004 Oct 22; 279(43):44327-34. PMID: 15280387.
    Citations: 25     Fields:    Translation:HumansCells
  42. Daniel S, Arvelo MB, Patel VI, Longo CR, Shrikhande G, Shukri T, Mahiou J, Sun DW, Mottley C, Grey ST, Ferran C. A20 protects endothelial cells from TNF-, Fas-, and NK-mediated cell death by inhibiting caspase 8 activation. Blood. 2004 Oct 15; 104(8):2376-84. PMID: 15251990.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
  43. Makhlouf L, Grey ST, Dong V, Csizmadia E, Arvelo MB, Auchincloss H, Ferran C, Sayegh MH. Depleting anti-CD4 monoclonal antibody cures new-onset diabetes, prevents recurrent autoimmune diabetes, and delays allograft rejection in nonobese diabetic mice. Transplantation. 2004 Apr 15; 77(7):990-7. PMID: 15087759.
    Citations: 14     Fields:    Translation:AnimalsCells
  44. Longo CR, Arvelo MB, Patel VI, Daniel S, Mahiou J, Grey ST, Ferran C. A20 protects from CD40-CD40 ligand-mediated endothelial cell activation and apoptosis. Circulation. 2003 Sep 02; 108(9):1113-8. PMID: 12885753.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  45. Grey ST, Longo C, Shukri T, Patel VI, Csizmadia E, Daniel S, Arvelo MB, Tchipashvili V, Ferran C. Genetic engineering of a suboptimal islet graft with A20 preserves beta cell mass and function. J Immunol. 2003 Jun 15; 170(12):6250-6. PMID: 12794157.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  46. Kunter U, Floege J, von Jürgensonn AS, Stojanovic T, Merkel S, Gröne HJ, Ferran C. Expression of A20 in the vessel wall of rat-kidney allografts correlates with protection from transplant arteriosclerosis. Transplantation. 2003 Jan 15; 75(1):3-9. PMID: 12544863.
    Citations: 11     Fields:    Translation:Animals
  47. Ferran C. The graft unveils its secrets: provocative therapeutic leads to protected vascularized allografts. Transpl Immunol. 2002 May; 9(2-4):135-6. PMID: 12180820.
    Citations:    Fields:    Translation:HumansAnimals
  48. Avihingsanon Y, Ma N, Csizmadia E, Wang C, Pavlakis M, Giraldo M, Strom TB, Soares MP, Ferran C. Expression of protective genes in human renal allografts: a regulatory response to injury associated with graft rejection. Transplantation. 2002 Apr 15; 73(7):1079-85. PMID: 11965035.
    Citations: 15     Fields:    Translation:Humans
  49. Arvelo MB, Cooper JT, Longo C, Daniel S, Grey ST, Mahiou J, Czismadia E, Abu-Jawdeh G, Ferran C. A20 protects mice from D-galactosamine/lipopolysaccharide acute toxic lethal hepatitis. Hepatology. 2002 Mar; 35(3):535-43. PMID: 11870365.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  50. Millan MT, Natkunam Y, Clarke-Katzenberg R, Desai D, Prapong W, So SK, Esquivel CO, Sibley R, Ferran C, Martinez OM. Epstein-Barr virus infection is associated with endothelial Bcl-2 expression in transplant liver allografts. Transplantation. 2002 Feb 15; 73(3):465-9. PMID: 11884946.
    Citations:    Fields:    Translation:HumansCells
  51. Laybutt DR, Kaneto H, Hasenkamp W, Grey S, Jonas JC, Sgroi DC, Groff A, Ferran C, Bonner-Weir S, Sharma A, Weir GC. Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to beta-cell survival during chronic hyperglycemia. Diabetes. 2002 Feb; 51(2):413-23. PMID: 11812749.
    Citations: 36     Fields:    Translation:Animals
  52. Rocha E, Mahiou J, Badrichani AZ, Stroka DM, Ferran C. The BH4 domain of A1, an anti-apoptotic bcl family gene, is necessary and sufficient for its antiinflammatory function in endothelial cells. Transplant Proc. 2001 Feb-Mar; 33(1-2):314. PMID: 11266835.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  53. Badrichani AZ, Ferran C. A20 and BCL proteins exert a broad and complementary cytoprotective effect in endothelial cells via blockade of NF-kappaB and NFAT. Transplant Proc. 2001 Feb-Mar; 33(1-2):450. PMID: 11266905.
    Citations:    Fields:    Translation:Animals
  54. Grey ST, Lock J, Bach FH, Ferran C. Adenovirus-mediated gene transfer of A20 in murine islets inhibits Fas-induced apoptosis. Transplant Proc. 2001 Feb-Mar; 33(1-2):577-8. PMID: 11266965.
    Citations: 1     Fields:    Translation:AnimalsCells
  55. Daniel S, Arvelo M, Ferran C. Overexpression of A20 in endothelial cells of vascularized grafts creates a protective barrier against TNF- and FAS-mediated apoptosis. Transplant Proc. 2001 Feb-Mar; 33(1-2):225. PMID: 11266789.
    Citations: 2     Fields:    Translation:AnimalsCells
  56. Grey ST, Arvelo MB, Hasenkamp W, Bach FH, Ferran C. A20 inhibits cytokine-induced apoptosis and nuclear factor kappaB-dependent gene activation in islets. J Exp Med. 1999 Oct 18; 190(8):1135-46. PMID: 10523611.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  57. Stroka DM, Badrichani AZ, Bach FH, Ferran C. Overexpression of A1, an NF-kappaB-inducible anti-apoptotic bcl gene, inhibits endothelial cell activation. Blood. 1999 Jun 01; 93(11):3803-10. PMID: 10339487.
    Citations: 11     Fields:    Translation:HumansCells
  58. Bach FH, Soares M, Lin Y, Ferran C. Barriers to xenotransplantation. Transplant Proc. 1999 Jun; 31(4):1819-20. PMID: 10371962.
    Citations:    Fields:    Translation:HumansAnimals
  59. Badrichani AZ, Stroka DM, Bilbao G, Curiel DT, Bach FH, Ferran C. Bcl-2 and Bcl-XL serve an anti-inflammatory function in endothelial cells through inhibition of NF-kappaB. J Clin Invest. 1999 Feb; 103(4):543-53. PMID: 10021463.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  60. Arvelo MB, Badrichani AZ, Stroka DM, Grey ST, Bach FH, Ferran C. A novel function for A20 in smooth muscle cells: inhibition of activation and proliferation. Transplant Proc. 1999 Feb-Mar; 31(1-2):858-9. PMID: 10083374.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  61. Grey ST, Arvelo MB, Hasenkamp WM, Bach FH, Ferran C. Adenovirus-mediated gene transfer of the anti-apoptotic protein A20 in rodent islets inhibits IL-1 beta-induced NO release. Transplant Proc. 1999 Feb-Mar; 31(1-2):789. PMID: 10083338.
    Citations: 1     Fields:    Translation:AnimalsCells
  62. von Albertini M, Ferran C, Brostjan C, Bach FH, Goodman DJ. Membrane-associated lymphotoxin on natural killer cells activates endothelial cells via an NF-kappaB-dependent pathway. Transplantation. 1998 Nov 15; 66(9):1211-9. PMID: 9825820.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  63. Soares MP, Muniappan A, Kaczmarek E, Koziak K, Wrighton CJ, Steinhäuslin F, Ferran C, Winkler H, Bach FH, Anrather J. Adenovirus-mediated expression of a dominant negative mutant of p65/RelA inhibits proinflammatory gene expression in endothelial cells without sensitizing to apoptosis. J Immunol. 1998 Nov 01; 161(9):4572-82. PMID: 9794384.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  64. Ferran C, Stroka DM, Badrichani AZ, Cooper JT, Wrighton CJ, Soares M, Grey ST, Bach FH. A20 inhibits NF-kappaB activation in endothelial cells without sensitizing to tumor necrosis factor-mediated apoptosis. Blood. 1998 Apr 01; 91(7):2249-58. PMID: 9516122.
    Citations: 34     Fields:    Translation:AnimalsCells
  65. Blanco R, Gonzalez-Gay MA, Ibañez D, Lopez-Viana A, Ferran C, Regueira A, Gonzalez-Vela C. Henoch-Schönlein purpura as clinical presentation of a myelodysplastic syndrome. Clin Rheumatol. 1997 Nov; 16(6):626-8. PMID: 9456018.
    Citations: 1     Fields:    Translation:Humans
  66. Bach FH, Hancock WW, Ferran C. Protective genes expressed in endothelial cells: a regulatory response to injury. Immunol Today. 1997 Oct; 18(10):483-6. PMID: 9357140.
    Citations: 31     Fields:    Translation:HumansAnimals
  67. Bach FH, Ferran C, Soares M, Wrighton CJ, Anrather J, Winkler H, Robson SC, Hancock WW. Modification of vascular responses in xenotransplantation: inflammation and apoptosis. Nat Med. 1997 Sep; 3(9):944-8. PMID: 9288711.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  68. Millan MT, Geczy C, Stuhlmeier KM, Goodman DJ, Ferran C, Bach FH. Human monocytes activate porcine endothelial cells, resulting in increased E-selectin, interleukin-8, monocyte chemotactic protein-1, and plasminogen activator inhibitor-type-1 expression. Transplantation. 1997 Feb 15; 63(3):421-9. PMID: 9039934.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  69. Stroka DM, Cooper JT, Brostjan C, Millan MT, Goodman DJ, Wrighton CJ, Bach FH, Ferran C. Expression of a negative dominant mutant of human p55 tumor necrosis factor-receptor inhibits TNF and monocyte-induced activation in porcine aortic endothelial cells. Transplant Proc. 1997 Feb-Mar; 29(1-2):882. PMID: 9123566.
    Citations:    Fields:    Translation:HumansAnimalsCells
  70. Cooper JT, Stroka DM, Brostjan C, Palmetshofer A, Bach FH, Ferran C. A20 expression inhibits endothelial cell activation. Transplant Proc. 1997 Feb-Mar; 29(1-2):881. PMID: 9123565.
    Citations: 2     Fields:    Translation:AnimalsCells
  71. Bach FH, Ferran C, Candinas D, Miyatake T, Koyamada N, Mark W, Hechenleitner P, Hancock WW. Accommodation of xenografts: expression of "protective genes" in endothelial and smooth muscle cells. Transplant Proc. 1997 Feb-Mar; 29(1-2):56-8. PMID: 9123128.
    Citations: 5     Fields:    Translation:AnimalsCells
  72. Bach FH, Ferran C, Hechenleitner P, Mark W, Koyamada N, Miyatake T, Winkler H, Badrichani A, Candinas D, Hancock WW. Accommodation of vascularized xenografts: expression of "protective genes" by donor endothelial cells in a host Th2 cytokine environment. Nat Med. 1997 Feb; 3(2):196-204. PMID: 9018239.
    Citations: 47     Fields:    Translation:AnimalsCells
  73. Ferran C, Stroka DM, Badrichani AZ, Cooper JT, Bach FH. Adenovirus-mediated gene transfer of A20 renders endothelial cells resistant to activation: a means of evaluating the role of endothelial cell activation in xenograft rejection. Transplant Proc. 1997 Feb-Mar; 29(1-2):879-80. PMID: 9123564.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  74. Ferran C, Badrichani AZ, Cooper JT, Stroka DM, Bach FH. Xenotransplantation: progress toward clinical development. Adv Nephrol Necker Hosp. 1997; 27:391-420. PMID: 9408458.
    Citations: 1     Fields:    Translation:Animals
  75. Bach FH, Winkler H, Ferran C, Hancock WW, Robson SC. Delayed xenograft rejection. Immunol Today. 1996 Aug; 17(8):379-84. PMID: 8783499.
    Citations: 33     Fields:    Translation:HumansAnimals
  76. Cooper JT, Stroka DM, Brostjan C, Palmetshofer A, Bach FH, Ferran C. A20 blocks endothelial cell activation through a NF-kappaB-dependent mechanism. J Biol Chem. 1996 Jul 26; 271(30):18068-73. PMID: 8663499.
    Citations: 68     Fields:    Translation:HumansAnimalsCells
  77. Ferran C, Cooper JT, Brostjan C, Stroka DM, Millan MT, Goodman DJ, Bach FH. Expression of a truncated form of the human p55 TNF-receptor in bovine aortic endothelial cells renders them resistant to human TNF. Transplant Proc. 1996 Apr; 28(2):618-9. PMID: 8623305.
    Citations:    Fields:    Translation:HumansAnimalsCells
  78. Bach FH, Winkler H, Wrighton CJ, Robson SC, Stuhlmeier K, Ferran C. Xenotransplantation: a possible solution to the shortage of donor organs. Transplant Proc. 1996 Feb; 28(1):416-7. PMID: 8644298.
    Citations:    Fields:    Translation:HumansAnimals
  79. Bach FH, Robson SC, Wrighton CJ, Stuhlmeier K, Ferran C, Winkler H. Genetic engineering of endothelial cells to ameliorate xenograft rejection. Clin Transplant. 1996 Feb; 10(1 Pt 2):124-7. PMID: 8680048.
    Citations: 1     Fields:    Translation:HumansAnimals
  80. Goumy L, Ferran C, Merite S, Bach JF, Chatenoud L. In vivo anti-CD3-driven cell activation. Cellular source of induced tumor necrosis factor, interleukin-1 beta, and interleukin-6. Transplantation. 1996 Jan 15; 61(1):83-7. PMID: 8560579.
    Citations: 3     Fields:    Translation:AnimalsCells
  81. Ferran C, Millan MT, Csizmadia V, Cooper JT, Brostjan C, Bach FH, Winkler H. Inhibition of NF-kappa B by pyrrolidine dithiocarbamate blocks endothelial cell activation. Biochem Biophys Res Commun. 1995 Sep 05; 214(1):212-23. PMID: 7545393.
    Citations: 12     Fields:    Translation:AnimalsCells
  82. Bach FH, Robson SC, Winkler H, Ferran C, Stuhlmeier KM, Wrighton CJ, Hancock WW. Barriers to xenotransplantation. Nat Med. 1995 Sep; 1(9):869-73. PMID: 7585204.
    Citations: 33     Fields:    Translation:HumansAnimals
  83. Bach FH, Robson SC, Ferran C, Millan M, Anrather J, Kopp C, Lesnikoski B, Goodman DJ, Hancock WW, Wrighton C, et al. Xenotransplantation: endothelial cell activation and beyond. Transplant Proc. 1995 Feb; 27(1):77-9. PMID: 7879178.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  84. Millan MT, Ferran C, Winkler H, Blakely ML, van der Werf WJ, Hancock WW, Bach FH. Xenotransplantation: problems and approaches. Transplant Proc. 1994 Dec; 26(6):3593-6. PMID: 7998285.
    Citations: 1     Fields:    Translation:HumansAnimals
  85. Bach FH, Robson SC, Ferran C, Winkler H, Millan MT, Stuhlmeier KM, Vanhove B, Blakely ML, van der Werf WJ, Hofer E, de Martin R, Hancock WW. Endothelial cell activation and thromboregulation during xenograft rejection. Immunol Rev. 1994 10; 141:5-30. PMID: 7868157.
    Citations: 16     Fields:    Translation:HumansAnimals
  86. Ferran C, Dautry F, Mérite S, Sheehan K, Schreiber R, Grau G, Bach JF, Chatenoud L. Anti-tumor necrosis factor modulates anti-CD3-triggered T cell cytokine gene expression in vivo. J Clin Invest. 1994 May; 93(5):2189-96. PMID: 8182150.
    Citations: 17     Fields:    Translation:AnimalsCells
  87. Ferran C, Bach JF, Chatenoud L. [Monoclonal antibodies. Diagnostic and therapeutic use and prospects for the future]. Rev Fr Transfus Hemobiol. 1993 Apr; 36(2):149-77. PMID: 8503970.
    Citations:    Fields:    Translation:Humans
  88. Ferran C, Bach JF, Chatenoud L. In vivo T cell activation properties of anti-T cell monoclonal antibodies. Exp Nephrol. 1993 Mar-Apr; 1(2):83-9. PMID: 8081961.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  89. Ferran C, Peuchmaur M, Desruennes M, Ghoussoub JJ, Cabrol A, Brousse N, Cabrol C, Bach JF, Chatenoud L. Implications of de novo ELAM-1 and VCAM-1 expression in human cardiac allograft rejection. Transplantation. 1993 Mar; 55(3):605-9. PMID: 7681227.
    Citations: 11     Fields:    Translation:Humans
  90. Ferran C. [T lymphocyte activation induced in vivo in different strains of mice after injection of anti-CD3 antibodies: prevention by an anti- TNF antibody]. Nephrologie. 1993; 14(1):23-4. PMID: 8502345.
    Citations:    Fields:    Translation:AnimalsCells
  91. Charpentier B, Hiesse C, Lantz O, Ferran C, Stephens S, O'Shaugnessy D, Bodmer M, Benoit G, Bach JF, Chatenoud L. Evidence that antihuman tumor necrosis factor monoclonal antibody prevents OKT3-induced acute syndrome. Transplantation. 1992 Dec; 54(6):997-1002. PMID: 1465794.
    Citations: 10     Fields:    Translation:HumansCTClinical Trials
  92. Ferran C, Dy M, Sheehan K, Merite S, Schreiber R, Landais P, Grau G, Bluestone J, Bach JF, Chatenoud L. Inter-mouse strain differences in the in vivo anti-CD3 induced cytokine release. Clin Exp Immunol. 1991 Dec; 86(3):537-43. PMID: 1721015.
    Citations: 9     Fields:    Translation:Animals
  93. Charpentier B, Hiesse C, Ferran C, Lantz O, Fries D, Bach JF, Chatenoud L. [Acute clinical syndrome associated with OKT3 administration. Prevention by single injection of an anti-human TNF monoclonal antibody]. Presse Med. 1991 Nov 27; 20(40):2009-11. PMID: 1837113.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  94. Ferran C, Dy M, Sheehan K, Schreiber R, Grau G, Bluestone J, Bach JF, Chatenoud L. Cascade modulation by anti-tumor necrosis factor monoclonal antibody of interferon-gamma, interleukin 3 and interleukin 6 release after triggering of the CD3/T cell receptor activation pathway. Eur J Immunol. 1991 Oct; 21(10):2349-53. PMID: 1833202.
    Citations: 10     Fields:    Translation:AnimalsCells
  95. Ferran C, Sheehan K, Schreiber R, Bach JF, Chatenoud L. Anti-TNF abrogates the cytokine-related anti-CD3 induced syndrome. Transplant Proc. 1991 Feb; 23(1 Pt 1):849-50. PMID: 1825003.
    Citations: 6     Fields:    Translation:Animals
  96. Chatenoud L, Legendre C, Ferran C, Bach JF, Kreis H. Corticosteroid inhibition of the OKT3-induced cytokine-related syndrome--dosage and kinetics prerequisites. Transplantation. 1991 Feb; 51(2):334-8. PMID: 1899732.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  97. Chatenoud L, Ferran C, Bach JF. Clinical applications of anti-T-cell monoclonal antibodies. Adv Nephrol Necker Hosp. 1991; 20:281-304. PMID: 2063717.
    Citations:    Fields:    Translation:HumansAnimalsCells
  98. Chatenoud L, Ferran C, Bach JF. The anti-CD3-induced syndrome: a consequence of massive in vivo cell activation. Curr Top Microbiol Immunol. 1991; 174:121-34. PMID: 1839376.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  99. Hardesty C, Ferran C, DiRienzo JM. Plasmid-mediated sucrose metabolism in Escherichia coli: characterization of scrY, the structural gene for a phosphoenolpyruvate-dependent sucrose phosphotransferase system outer membrane porin. J Bacteriol. 1991 Jan; 173(2):449-56. PMID: 1846143.
    Citations: 22     Fields:    Translation:Cells
  100. Chatenoud L, Ferran C, Bach JF. In vivo use of OKT3: main issues for the monitoring of treated patients. Transplant Proc. 1990 Dec; 22(6):2605-8. PMID: 2124743.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  101. Ferran C, Dy M, Merite S, Sheehan K, Schreiber R, Leboulenger F, Landais P, Bluestone J, Bach JF, Chatenoud L. Reduction of morbidity and cytokine release in anti-CD3 MoAb-treated mice by corticosteroids. Transplantation. 1990 Oct; 50(4):642-8. PMID: 1699310.
    Citations: 16     Fields:    Translation:Animals
  102. Chatenoud L, Ferran C, Legendre C, Kurrle R, Kreis H, Bach JF. Immunological follow-up of renal allograft recipients treated with the BMA 031 (anti-TCR) monoclonal antibody. Transplant Proc. 1990 Aug; 22(4):1787-8. PMID: 2117809.
    Citations: 2     Fields:    Translation:HumansCells
  103. Ferran C, Bluestone J, Bach JF, Chatenoud L. In vivo T lymphocyte activation induced in mice following the injection of anti-CD3 monoclonal antibody. Transplant Proc. 1990 Aug; 22(4):1922-3. PMID: 2143865.
    Citations: 4     Fields:    Translation:AnimalsCells
  104. Chatenoud L, Ferran C, Legendre C, Thouard I, Merite S, Reuter A, Gevaert Y, Kreis H, Franchimont P, Bach JF. In vivo cell activation following OKT3 administration. Systemic cytokine release and modulation by corticosteroids. Transplantation. 1990 Apr; 49(4):697-702. PMID: 2109379.
    Citations: 45     Fields:    Translation:Humans
  105. Ferran C, Sheehan K, Dy M, Schreiber R, Merite S, Landais P, Noel LH, Grau G, Bluestone J, Bach JF, et al. Cytokine-related syndrome following injection of anti-CD3 monoclonal antibody: further evidence for transient in vivo T cell activation. Eur J Immunol. 1990 Mar; 20(3):509-15. PMID: 2138557.
    Citations: 58     Fields:    Translation:AnimalsCells
  106. Chatenoud L, Ferran C, Bach JF. In-vivo anti-CD3 treatment of autoimmune patients. Lancet. 1989 Jul 15; 2(8655):164. PMID: 2567934.
    Citations: 3     Fields:    Translation:Humans
  107. Chatenoud L, Ferran C, Reuter A, Legendre C, Gevaert Y, Kreis H, Franchimont P, Bach JF. Systemic reaction to the anti-T-cell monoclonal antibody OKT3 in relation to serum levels of tumor necrosis factor and interferon-gamma [corrected]. N Engl J Med. 1989 May 25; 320(21):1420-1. PMID: 2785642.
    Citations: 36     Fields:    Translation:HumansCells
  108. Pochet JM, Albouze G, Bobrie G, Landais P, Ferran C, Grünfeld JP. The natural history of inherited renal diseases. Contrib Nephrol. 1989; 75:100-7. PMID: 2697494.
    Citations:    Fields:    Translation:Humans
  109. Chatenoud L, Ferran C, Reuter A, Legendre C, Gevaert Y, Kreis H, Franchimont P, Bach JF. [T lymphocyte activation induced in vivo by the first injection of OKT3 monoclonal antibodies]. C R Acad Sci III. 1988; 307(19):833-6. PMID: 3146414.
    Citations:    Fields:    Translation:HumansCells
  110. Hardesty C, Colón G, Ferran C, DiRienzo JM. Deletion analysis of sucrose metabolic genes from a Salmonella plasmid cloned in Escherichia coli K12. Plasmid. 1987 Sep; 18(2):142-55. PMID: 2829252.
    Citations: 3     Fields:    Translation:Cells
  111. Laborit H, Baron C, Ferran C, Henriet I. Action of certain pharmacological associations on the level of cerebral biogenic amines and some metabolites in the curative treatment of hemorrhagic shock in rats. Res Commun Chem Pathol Pharmacol. 1984 Mar; 43(3):435-47. PMID: 6371956.
    Citations:    Fields:    Translation:Animals
  112. Laborit H, Baron C, Ferran C, Henriet I. Assay of cerebral catecholamines, serotonin and their metabolites in experimental hemorrhagic shock in rats. Res Commun Chem Pathol Pharmacol. 1984 Mar; 43(3):425-33. PMID: 6718809.
    Citations:    Fields:    Translation:Animals
  113. Bonifacj JF, Ferran C, Laborit H. [Effect of piracetam on metabolic stages in the rat brain]. Agressologie. 1982 Oct; 23(4):127-9. PMID: 7180984.
    Citations:    Fields:    Translation:Animals
  114. Laborit H, Baron C, Ferran C, Henriet I. [Effect of minaprine on arterial pressure and levels of cerebral amines in spontaneously hypertensive rats]. Agressologie. 1982 Mar; 23(1):15-8. PMID: 6125104.
    Citations:    Fields:    Translation:Animals
  115. Ferran C. [Life-expectancy in the acute leukaemias (author's transl)]. Sangre (Barc). 1981; 26(5-C):1028-32. PMID: 7323924.
    Citations:    Fields:    Translation:Humans
  116. Laborit H, Baron C, Ferran C, Henriet I. [Variations in blood lactic acid and glucose levels in the rabbit after infusion of isoprenaline with or without prior infusion of minaprine]. Agressologie. 1981; 22(2):63-4. PMID: 7270796.
    Citations: 1     Fields:    Translation:Animals
  117. Laborit H, Baron C, Ferran C, Henriet I. [Effects of minaprine hydrochloride on changes in body weight, blood pressure and cerebral amine concentrations induced by unavoidable planter electric shock]. Agressologie. 1981; 22(2):59-62. PMID: 7270795.
    Citations:    Fields:    Translation:Animals
  118. Laborit H, Baron C, Ferran C, Bonifacj JF, Topall G, Henriet I. [Variations in the toxicity of cadmium in relation to the possibility of controlling the environmental status by motor activity in the rat]. Agressologie. 1980; 21(6):269-90. PMID: 7294291.
    Citations:    Fields:    Translation:Animals
  119. Laborit H, Baron C, Ferran C, Laborit G. [Biochemical and neurophysiological study of various fish toxins]. Agressologie. 1979; 20(2):81-96. PMID: 507325.
    Citations:    Fields:    Translation:Animals
  120. Vivancos Pujol MP, Alemany A, Clavo M, Rubio Baget A, Sans Botargues R, Ferran C. [Granulocyte transfusion. Its efficacy as a complementary treatment of infections in the granulocytopenic patient (author's transl)]. Sangre (Barc). 1979; 24(5B):896-903. PMID: 524234.
    Citations:    Fields:    Translation:HumansCells
  121. Laborit H, Ferran C. [Decrease in erythrocyte 2,3 diphosphoglycerate levels in relation to elevated lactate concentration in the medium and restoration of these levels under the influence of dihydroxyacetone]. Agressologie. 1976; 17(5):265-71. PMID: 1015548.
    Citations:    Fields:    Translation:AnimalsCells
  122. Rozman C, Triginer J, Ribas-Mundo M, Ferran C, Visa J, Gonzales E. The value of laparotomy and splenectomy in the staging of 56 patients with Hodgkin's disease. Acta Haematol. 1973; 50(6):321-8. PMID: 4205168.
    Citations: 1     Fields:    Translation:Humans
  123. Ferran C, González E, Arangüena PV, Irriguible MD, Acebedo G, Rubio D, García J, Triginer J, Lara F. [Laparotomy in Hodgkin's disease]. Sangre (Barc). 1972; 17(3):301-8. PMID: 5081387.
    Citations:    Fields:    Translation:Humans
  124. Muxi M, Perez Soler J, Mateu JM, Morales V, Ferran C, Alonso C, Jordan C, Gonzales E, Salvador Monte R. [Intrauterine transfusion]. Minerva Ginecol. 1970 Jul 13; 22(14):701-3. PMID: 5498888.
    Citations:    Fields:    
  125. Muxi M, Perez Soler J, Mateu JM, Morales V, Ferran C, Alonso C, Jordan C, Gonzales E. [Study of the amniotic fluid]. Minerva Ginecol. 1970 Jul 13; 22(14):716-8. PMID: 5498892.
    Citations:    Fields:    
  126. Ferran C. [Psychotropic drugs and placebos in a medico-pedagogical institute. Introduction to a study of the psycho-affective reactions produced within the care team by prescription]. Rev Neuropsychiatr Infant. 1969 Dec; 17(12):827-33. PMID: 4391698.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  127. DARMAILLACQ R, FERRAN C, GAUTIER G. [Torsions of the great omentum. Apropos of 3 cases]. Bord Chir. 1961 Apr; 2:73-8. PMID: 13719784.
    Citations:    Translation:Humans
  128. FERRAN C. [Not Available]. Toulouse Med. 1948 May; 49(5):365-70. PMID: 18876283.
    Citations:    
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.