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Anne Hansen, M.D.


Haverford College, Haverford, PAB.A.1985Anthropology
Harvard Medical School, Boston, MAM.D.1990Medicine
Harvard School of Public Health, Boston, MAM.P.H.1995Clinical Effectiveness

Dr. Anne Hansen received her MD from Harvard Medical School and then went to Boston Children’s Hospital for her pediatric internship and residency. She stayed in Boston for her fellowship in Newborn Medicine at the combined program between Children’s, Beth Israel, and Brigham and Women’s Hospitals. She obtained her M.P.H. with a concentration in Clinical Effectiveness from Harvard School of Public Health. She joined the Harvard Medical School faculty in 1996 and is currently an Associate Professor of Pediatrics. Dr. Anne Hansen has been the Medical Director of the Neonatal Intensive Care Unit at Boston Children’s Hospital since 2003. She has authored dozens of clinical guidelines, and is a chair or member of multiple unit based and hospital wide committees. She is a Fellow in the American Academy of Pediatrics. An acclaimed teacher, she is the recipient of the Merton Bernfield mentoring award, the Harvard Medical School Humanism Award, and the Tutor of the Year Award at Harvard Medical School. Dr. Hansen has published over 35 peer reviewed articles, 53 chapters and 8 books.

Dr. Hansen’s research focuses on improving the care of newborns seriously ill with medical and surgical conditions, medical device development, and global health. She has been working since 2010 in collaboration with the Rwanda Ministry of Health (MOH) and Partners In Health (PIH) to develop and implement national standards for newborn care. Recently, they have written a 2nd edition and conducted national trainings with nurses and doctors from all Rwandan provincial hospitals. She is currently working with OPENPediatrics, a free, open-access on-line medical education platform based at Boston Children’s Hospital, to make the Rwandan neonatal protocols, taught by Rwandan doctors and nurses, available as videos to pediatricians around the world. Working with the Rwanda MOH, PIH and Lawrence Berkeley National Laboratory’s Institute for Globally Transformative Technologies, she has developed a simple, inexpensive, re-usable nonelectric infant warmer that has been tested successfully in Rwanda; She is now working to scale it nationally across Rwanda, as well as globally.

Closer to home, Dr Hansen is collaborating with engineers and industry to develop a Central Venous Catheter with decreased propensity for infection or clot formation. In collaboration with surgeons and industry, she has developed a novel, minimally invasive approach to esophageal growth induction for patients with long gap esophageal atresia. She has examined innovative approaches to the treatment of neonatal conditions including intraventricular urokinase for the prevention of post hemorrhagic hydrocephalus, once daily gentamicin dosing for infants, substitution of cord for infant blood in perinatal sepsis evaluations, and inhaled racemic epinephrine for the treatments of TTN. She was lead investigator in a study of Donation after Cardiac Death (DCD) in the NICU. She developed and implemented the first therapeutic hypothermia program in New England. She is a co-editor of the Manual of Neonatal Care, now in its 8th edition, and co-editor of the Manual of Neonatal Surgical Intensive care, now in its 3rd edition.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Leeman KT, Barbas K, Strauss J, Adams S, Sussman-Karten K, Kelly A, Parker MGK, Hansen A. Improving Access to Lactation Consultation and Early Breast Milk Use in an Outborn NICU. Pediatr Qual Saf. 2019 Jan-Feb; 4(1):e130. PMID: 30937412; PMCID: PMC6426487.
    Citations: 3     
  2. Resnick CM, LeVine J, Calabrese CE, Padwa BL, Hansen A, Katwa U. Early Management of Infants With Robin Sequence: An International Survey and Algorithm. J Oral Maxillofac Surg. 2019 Jan; 77(1):136-156. PMID: 30599883.
    Citations: 4     Fields:    Translation:Humans
  3. Morton SU, Belfort MB, Kahlon PS, Hajizadeh Barfjani S, Rudie C, Hashim E, Hansen A, Huh SY. Reducing time to initiation and advancement of enteral feeding in an all-referral neonatal intensive care unit. J Perinatol. 2018 07; 38(7):936-943. PMID: 29740193.
    Citations: 2     Fields:    Translation:Humans
  4. Angelidou A, Bell K, Gupta M, Tropea Leeman K, Hansen A. Implementation of a Guideline to Decrease Use of Acid-Suppressing Medications in the NICU. Pediatrics. 2017 Dec; 140(6). PMID: 29162657.
    Citations: 4     Fields:    Translation:Humans
  5. Twichell SA, Fiascone J, Gupta M, Prendergast M, Rodig N, Hansen A. A Regional Evaluation of Survival of Infants with End-Stage Renal Disease. Neonatology. 2017; 112(1):73-79. PMID: 28359062.
    Citations:    Fields:    Translation:Humans
  6. ) Hansen A, Magge H, Labrecque M, Munyanez R, Nahimana E, Nyishime M, Mwali A. The Development and Implementation of a Newborn Medicine Program in a Resource Limited Setting . Public Health Action. 2015.
  7. Leslie DC, Waterhouse A, Berthet JB, Valentin TM, Watters AL, Jain A, Kim P, Hatton BD, Nedder A, Donovan K, Super EH, Howell C, Johnson CP, Vu TL, Bolgen DE, Rifai S, Hansen AR, Aizenberg M, Super M, Aizenberg J, Ingber DE. A bioinspired omniphobic surface coating on medical devices prevents thrombosis and biofouling. Nat Biotechnol. 2014 Nov; 32(11):1134-40. PMID: 25306244.
    Citations: 89     Fields:    Translation:HumansAnimalsPHPublic Health
  8. Jørgensen TS, Hansen AH, Sahlberg M, Gislason GH, Torp-Pedersen C, Andersson C, Holm E. Falls and comorbidity: the pathway to fractures. Scand J Public Health. 2014 May; 42(3):287-94. PMID: 24434943.
    Citations: 11     Fields:    Translation:Humans
  9. Gupta M, Ringer S, Tess A, Hansen A, Zupancic J. Developing a quality and safety curriculum for fellows: lessons learned from a neonatology fellowship program. Acad Pediatr. 2014 Jan-Feb; 14(1):47-53. PMID: 24126046.
    Citations: 5     Fields:    Translation:Humans
  10. Touma M, Joshi M, Connolly MC, Grant PE, Hansen AR, Khwaja O, Berry GT, Kinney HC, Poduri A, Agrawal PB. Whole genome sequencing identifies SCN2A mutation in monozygotic twins with Ohtahara syndrome and unique neuropathologic findings. Epilepsia. 2013 May; 54(5):e81-5. PMID: 23550958.
    Citations: 21     Fields:    Translation:Humans
  11. Wintermark P, Boyd T, Gregas MC, Labrecque M, Hansen A. Placental pathology in asphyxiated newborns meeting the criteria for therapeutic hypothermia. Am J Obstet Gynecol. 2010 Dec; 203(6):579.e1-9. PMID: 20851370.
    Citations: 33     Fields:    Translation:Humans
  12. Wintermark P, Labrecque M, Warfield SK, DeHart S, Hansen A. Can induced hypothermia be assured during brain MRI in neonates with hypoxic-ischemic encephalopathy? Pediatr Radiol. 2010 Dec; 40(12):1950-4. PMID: 20737144.
    Citations: 14     Fields:    Translation:Humans
  13. Labrecque M, Parad R, Gupta M, Hansen A. Donation after cardiac death: the potential contribution of an infant organ donor population. J Pediatr. 2011 Jan; 158(1):31-6. PMID: 20732689.
    Citations: 3     Fields:    Translation:Humans
  14. Meyer EC, Brodsky D, Hansen AR, Lamiani G, Sellers DE, Browning DM. An interdisciplinary, family-focused approach to relational learning in neonatal intensive care. J Perinatol. 2011 Mar; 31(3):212-9. PMID: 20706191.
    Citations: 12     Fields:    Translation:Humans
  15. Wintermark P, Hansen A, Soul J, Labrecque M, Robertson RL, Warfield SK. Early versus late MRI in asphyxiated newborns treated with hypothermia. Arch Dis Child Fetal Neonatal Ed. 2011 Jan; 96(1):F36-44. PMID: 20688865; PMCID: PMC3335299.
    Citations: 25     Fields:    Translation:Humans
  16. Barnes CM, McElrath TF, Folkman J, Hansen AR. Correlation of 2-methoxyestradiol levels in cord blood and complications of prematurity. Pediatr Res. 2010 May; 67(5):545-50. PMID: 20098341.
    Citations: 8     Fields:    Translation:Humans
  17. Goldfield EC, Buonomo C, Fletcher K, Perez J, Margetts S, Hansen A, Smith V, Ringer S, Richardson MJ, Wolff PH. Premature infant swallowing: patterns of tongue-soft palate coordination based upon videofluoroscopy. Infant Behav Dev. 2010 Apr; 33(2):209-18. PMID: 20181397.
    Citations: 6     Fields:    Translation:Humans
  18. Hansen AR, Barnés CM, Folkman J, McElrath TF. Maternal preeclampsia predicts the development of bronchopulmonary dysplasia. J Pediatr. 2010 Apr; 156(4):532-6. PMID: 20004912.
    Citations: 65     Fields:    Translation:HumansPHPublic Health
  19. Degn SE, Hansen AG, Steffensen R, Jacobsen C, Jensenius JC, Thiel S. MAp44, a human protein associated with pattern recognition molecules of the complement system and regulating the lectin pathway of complement activation. J Immunol. 2009 Dec 01; 183(11):7371-8. PMID: 19917686.
    Citations: 59     Fields:    Translation:HumansAnimalsCells
  20. Thiel S, Kolev M, Degn S, Steffensen R, Hansen AG, Ruseva M, Jensenius JC. Polymorphisms in mannan-binding lectin (MBL)-associated serine protease 2 affect stability, binding to MBL, and enzymatic activity. J Immunol. 2009 Mar 01; 182(5):2939-47. PMID: 19234189.
    Citations: 22     Fields:    Translation:HumansCells
  21. Aslam M, Guglietti D, Hansen AR. Neonatal arterial thrombosis at birth: case report and literature review. Am J Perinatol. 2008 Jun; 25(6):347-52. PMID: 18509789.
    Citations: 6     Fields:    Translation:Humans
  22. Kao B, Stewart de Ramirez SA, Belfort MB, Hansen A. Inhaled epinephrine for the treatment of transient tachypnea of the newborn. J Perinatol. 2008 Mar; 28(3):205-10. PMID: 18200024.
    Citations: 6     Fields:    Translation:Humans
  23. Nybo M, Brusgaard K, Hansen AB. No certain predictors for mutation status in a Danish cohort with familial hypercholesterolemia: a descriptive study. Clin Biochem. 2007 Dec; 40(18):1347-52. PMID: 17961529.
    Citations: 1     Fields:    Translation:Humans
  24. Hansen A, Forbes P, Buck R. Potential substitution of cord blood for infant blood in the neonatal sepsis evaluation. Biol Neonate. 2005; 88(1):12-8. PMID: 15711036.
    Citations: 14     Fields:    Translation:Humans
  25. Hansen AR, Madsen JR. Antenatal neurosurgical counseling: approach to the unborn patient. Pediatr Clin North Am. 2004 Apr; 51(2):491-505. PMID: 15062681.
    Citations:    Fields:    Translation:Humans
  26. Hansen A, Forbes P, Arnold A, O'Rourke E. Once-daily gentamicin dosing for the preterm and term newborn: proposal for a simple regimen that achieves target levels. J Perinatol. 2003 Dec; 23(8):635-9. PMID: 14647159.
    Citations: 10     Fields:    Translation:Humans
  27. Hansen AR, Collins MH, Genest D, Heller D, Shen-Schwarz S, Banagon P, Allred EN, Leviton A. Very low birthweight placenta: clustering of morphologic characteristics. Pediatr Dev Pathol. 2000 Sep-Oct; 3(5):431-8. PMID: 10890927.
    Citations: 10     Fields:    Translation:Humans
  28. Hansen AR, Collins MH, Genest D, Heller D, Schwarz S, Banagon P, Allred EN, Leviton A. Very low birthweight Infant's placenta and its relation to pregnancy and fetal characteristics. Pediatr Dev Pathol. 2000 Sep-Oct; 3(5):419-30. PMID: 10890926.
    Citations: 5     Fields:    Translation:Humans
  29. Hansen AR, Lapp C, Brugnara C. Plasminogen activator inhibitor-1: defining characteristics in the cerebrospinal fluid of newborns. J Pediatr. 2000 Jul; 137(1):132-4. PMID: 10891836.
    Citations: 3     Fields:    Translation:Humans
  30. Hansen AR, DiSalvo D, Kazam E, Allred EN, Leviton A. Sonographically detected subarachnoid hemorrhage: an independent predictor of neonatal posthemorrhagic hydrocephalus? Clin Imaging. 2000 May-Jun; 24(3):121-9. PMID: 11150676.
    Citations: 1     Fields:    Translation:Humans
  31. Hansen A, Leviton A. Labor and delivery characteristics and risks of cranial ultrasonographic abnormalities among very-low-birth-weight infants. The Developmental Epidemiology Network Investigators. Am J Obstet Gynecol. 1999 Oct; 181(4):997-1006. PMID: 10521768.
    Citations: 3     Fields:    Translation:Humans
  32. Haller GW, Esnaola N, Yamada K, Wu A, Shimizu A, Hansen A, Ferrara VR, Allison KS, Colvin RB, Sykes M, Sachs DH. Thymic transplantation across an MHC class I barrier in swine. J Immunol. 1999 Oct 01; 163(7):3785-92. PMID: 10490976.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  33. Hansen AR, Snyder EY. Medical management of neonatal posthemorrhagic hydrocephalus. Neurosurg Clin N Am. 1998 Jan; 9(1):95-104. PMID: 9405767.
    Citations:    Fields:    Translation:Humans
  34. Hansen AR. CNS fibrinolysis: a review of the literature with a pediatric emphasis. Pediatr Neurol. 1998 Jan; 18(1):15-21. PMID: 9492086.
    Citations: 2     Fields:    Translation:HumansAnimalsCTClinical Trials
  35. Hansen AR, Volpe JJ, Goumnerova LC, Madsen JR. Intraventricular urokinase for the treatment of posthemorrhagic hydrocephalus. Pediatr Neurol. 1997 Oct; 17(3):213-7. PMID: 9390696.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  36. Hansen AR, Allred EN, Leviton A. Predictors of ventriculoperitoneal shunt among babies with intraventricular hemorrhage. J Child Neurol. 1997 Sep; 12(6):381-6. PMID: 9309522.
    Citations: 4     Fields:    Translation:Humans
  37. Hansen A, Whitelaw A, Lapp C, Brugnara C. Cerebrospinal fluid plasminogen activator inhibitor-1: a prognostic factor in posthaemorrhagic hydrocephalus. Acta Paediatr. 1997 Sep; 86(9):995-8. PMID: 9343282.
    Citations: 10     Fields:    Translation:Humans
  38. Hansen A, Guerina N, Lerman-Sagie T, Korson M. Central apnea in a child with congenital autonomic dysfunction and universal pain loss. J Child Neurol. 1996 Mar; 11(2):162-4. PMID: 8881995.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.