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Philip J Saylor, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Alchahin AM, Mei S, Tsea I, Hirz T, Kfoury Y, Dahl D, Wu CL, Subtelny AO, Wu S, Scadden DT, Shin JH, Saylor PJ, Sykes DB, Kharchenko PV, Baryawno N. A transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma. Nat Commun. 2022 Sep 30; 13(1):5747. PMID: 36180422; PMCID: PMC9525645.
    Citations: 1     Fields:    Translation:HumansCells
  2. Kfoury Y, Baryawno N, Severe N, Mei S, Gustafsson K, Hirz T, Brouse T, Scadden EW, Igolkina AA, Kokkaliaris K, Choi BD, Barkas N, Randolph MA, Shin JH, Saylor PJ, Scadden DT, Sykes DB, Kharchenko PV. Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment. Cancer Cell. 2021 11 08; 39(11):1464-1478.e8. PMID: 34719426; PMCID: PMC8578470.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  3. Saylor PJ. Informed Consent 2021: The "Terms and Conditions" of the Research World. Oncologist. 2021 11; 26(11):902-903. PMID: 34176191.
    Citations:    Fields:    Translation:Humans
  4. Massaad E, Saylor PJ, Hadzipasic M, Kiapour A, Oh K, Schwab JH, Schoenfeld AJ, Shankar GM, Shin JH. The effectiveness of systemic therapies after surgery for metastatic renal cell carcinoma to the spine: a propensity analysis controlling for sarcopenia, frailty, and nutrition. J Neurosurg Spine. 2021 Jun 25; 1-10. PMID: 34171829.
    Citations: 1     Fields:    
  5. Calagua C, Ficial M, Jansen CS, Hirz T, Del Balzo L, Wilkinson S, Lake R, Ku AT, Voznesensky O, Sykes DB, Saylor PJ, Ye H, Signoretti S, Kissick H, Sowalsky AG, Balk SP, Einstein DJ. A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes. Clin Cancer Res. 2021 09 01; 27(17):4836-4847. PMID: 34168052; PMCID: PMC8416924.
    Citations: 2     Fields:    Translation:HumansCells
  6. Sciubba DM, Pennington Z, Colman MW, Goodwin CR, Laufer I, Patt JC, Redmond KJ, Saylor P, Shin JH, Schwab JH, Schoenfeld AJ. Spinal metastases 2021: a review of the current state of the art and future directions. Spine J. 2021 09; 21(9):1414-1429. PMID: 33887454.
    Citations: 1     Fields:    Translation:Humans
  7. Guarda FJ, Yu X, Shiraliyeva N, Haines MS, Bradbury M, Saylor PJ, Nachtigall LB. GnRH agonist-associated pituitary apoplexy: a case series and review of the literature. Pituitary. 2021 Oct; 24(5):681-689. PMID: 33835355.
    Citations:    Fields:    Translation:Humans
  8. Shankar GM, Van Beaver LA, Choi BD, Hadzipasic M, Sivaganesan A, Karhade AV, Ferrone ML, Harris MB, Schoenfeld AJ, Sadow PM, Oh K, Schwab JH, Saylor PJ, Shin JH. Survival After Surgery for Renal Cell Carcinoma Metastatic to the Spine: Impact of Modern Systemic Therapies on Outcomes. Neurosurgery. 2020 11 16; 87(6):1174-1180. PMID: 32521012.
    Citations: 1     Fields:    Translation:Humans
  9. Barata P, Agarwal N, Nussenzveig R, Gerendash B, Jaeger E, Hatton W, Ledet E, Lewis B, Layton J, Babiker H, Bryce A, Garje R, Stein C, Kiedrowski L, Saylor P, Sartor O. Clinical activity of pembrolizumab in metastatic prostate cancer with microsatellite instability high (MSI-H) detected by circulating tumor DNA. J Immunother Cancer. 2020 08; 8(2). PMID: 32788235.
    Citations: 20     Fields:    Translation:HumansPHPublic Health
  10. Massaad E, Hadzipasic M, Alvarez-Breckenridge C, Kiapour A, Fatima N, Schwab JH, Saylor P, Oh K, Schoenfeld AJ, Shankar GM, Shin JH. Predicting tumor-specific survival in patients with spinal metastatic renal cell carcinoma: which scoring system is most accurate? J Neurosurg Spine. 2020 Jun 05; 1-11. PMID: 32502990.
    Citations: 1     Fields:    
  11. Saylor PJ, Rumble RB, Michalski JM. Bone Health and Bone-Targeted Therapies for Prostate Cancer: American Society of Clinical Oncology Endorsement Summary of a Cancer Care Ontario Guideline. JCO Oncol Pract. 2020 07; 16(7):389-393. PMID: 32074010.
    Citations: 4     Fields:    Translation:Humans
  12. Saylor PJ, Rumble RB, Tagawa S, Eastham JA, Finelli A, Reddy PS, Kungel TM, Nissenberg MG, Michalski JM. Bone Health and Bone-Targeted Therapies for Prostate Cancer: ASCO Endorsement of a Cancer Care Ontario Guideline. J Clin Oncol. 2020 05 20; 38(15):1736-1743. PMID: 31990618.
    Citations: 15     Fields:    Translation:Humans
  13. Gilligan T, Lin DW, Aggarwal R, Chism D, Cost N, Derweesh IH, Emamekhoo H, Feldman DR, Geynisman DM, Hancock SL, LaGrange C, Levine EG, Longo T, Lowrance W, McGregor B, Monk P, Picus J, Pierorazio P, Rais-Bahrami S, Saylor P, Sircar K, Smith DC, Tzou K, Vaena D, Vaughn D, Yamoah K, Yamzon J, Johnson-Chilla A, Keller J, Pluchino LA. Testicular Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2019 12; 17(12):1529-1554. PMID: 31805523.
    Citations: 35     Fields:    Translation:Humans
  14. Karhade AV, Thio QCBS, Ogink PT, Bono CM, Ferrone ML, Oh KS, Saylor PJ, Schoenfeld AJ, Shin JH, Harris MB, Schwab JH. Predicting 90-Day and 1-Year Mortality in Spinal Metastatic Disease: Development and Internal Validation. Neurosurgery. 2019 10 01; 85(4):E671-E681. PMID: 30869143.
    Citations: 30     Fields:    Translation:Humans
  15. Amorim BJ, Prabhu V, Marco SS, Gervais D, Palmer WE, Heidari P, Vangel M, Saylor PJ, Catalano OA. Performance of 18F-fluciclovine PET/MR in the evaluation of osseous metastases from castration-resistant prostate cancer. Eur J Nucl Med Mol Imaging. 2020 01; 47(1):105-114. PMID: 31492992.
    Citations: 2     Fields:    Translation:Humans
  16. Karhade AV, Thio QCBS, Ogink PT, Shah AA, Bono CM, Oh KS, Saylor PJ, Schoenfeld AJ, Shin JH, Harris MB, Schwab JH. Development of Machine Learning Algorithms for Prediction of 30-Day Mortality After Surgery for Spinal Metastasis. Neurosurgery. 2019 07 01; 85(1):E83-E91. PMID: 30476188.
    Citations: 28     Fields:    Translation:Humans
  17. Saylor PJ, Dudzinski DM, Mendoza DP, Glomski K. Case 14-2019: A 44-Year-Old Man with Neck Pain and Swelling. N Engl J Med. 2019 May 09; 380(19):1854-1863. PMID: 31067377.
    Citations: 1     Fields:    Translation:Humans
  18. Dahl DM, Simeone JF, Iliopoulos O, Saylor PJ, Wu CL. Case 36-2018: A 29-Year-Old Man with an Incidentally Discovered Renal Mass. N Engl J Med. 2018 11 22; 379(21):2064-2072. PMID: 30462933.
    Citations:    Fields:    Translation:Humans
  19. Coen JJ, Zhang P, Saylor PJ, Lee CT, Wu CL, Parker W, Lautenschlaeger T, Zietman AL, Efstathiou JA, Jani AB, Kucuk O, Souhami L, Rodgers JP, Sandler HM, Shipley WU. Bladder Preservation With Twice-a-Day Radiation Plus Fluorouracil/Cisplatin or Once Daily Radiation Plus Gemcitabine for Muscle-Invasive Bladder Cancer: NRG/RTOG 0712-A Randomized Phase II Trial. J Clin Oncol. 2019 01 01; 37(1):44-51. PMID: 30433852.
    Citations: 21     Fields:    Translation:HumansCTClinical Trials
  20. Giacalone NJ, Shipley WU, Clayman RH, Niemierko A, Drumm M, Heney NM, Michaelson MD, Lee RJ, Saylor PJ, Wszolek MF, Feldman AS, Dahl DM, Zietman AL, Efstathiou JA. Long-term Outcomes After Bladder-preserving Tri-modality Therapy for Patients with Muscle-invasive Bladder Cancer: An Updated Analysis of the Massachusetts General Hospital Experience. Eur Urol. 2017 06; 71(6):952-960. PMID: 28081860.
    Citations: 76     Fields:    Translation:Humans
  21. Saylor PJ, Lee RJ, Arora KS, Deshpande V, Hu R, Olivier K, Meneely E, Rivera MN, Ting DT, Wu CL, Miyamoto DT. Branched Chain RNA In Situ Hybridization for Androgen Receptor Splice Variant AR-V7 as a Prognostic Biomarker for Metastatic Castration-Sensitive Prostate Cancer. Clin Cancer Res. 2017 Jan 15; 23(2):363-369. PMID: 27440270.
    Citations: 12     Fields:    Translation:HumansCells
  22. Singh H, Liu Y, Xiao X, Lin L, Kim J, Van Hummelen P, Wu CL, Bass AJ, Saylor PJ. Whole exome sequencing of urachal adenocarcinoma reveals recurrent NF1 mutations. Oncotarget. 2016 May 17; 7(20):29211-5. PMID: 27078850.
    Citations: 11     Fields:    Translation:Humans
  23. Pallais JC, McInnis M, Saylor PJ, Wu RI. CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 38-2015. A 21-Year-Old Man with Fatigue and Weight Loss. N Engl J Med. 2015 Dec 10; 373(24):2358-69. PMID: 26650156.
    Citations: 1     Fields:    Translation:Humans
  24. Ryan CJ, Saylor PJ, Everly JJ, Sartor O. Bone-targeting radiopharmaceuticals for the treatment of bone-metastatic castration-resistant prostate cancer: exploring the implications of new data. Oncologist. 2014 Oct; 19(10):1012-8. PMID: 25232039.
    Citations: 8     Fields:    Translation:Humans
  25. Saylor PJ. Bone targeted therapies for the prevention of skeletal morbidity in men with prostate cancer. Asian J Androl. 2014 May-Jun; 16(3):341-7. PMID: 24435057.
    Citations: 6     Fields:    Translation:HumansCells
  26. Smith MR, Halabi S, Ryan CJ, Hussain A, Vogelzang N, Stadler W, Hauke RJ, Monk JP, Saylor P, Bhoopalam N, Saad F, Sanford B, Kelly WK, Morris M, Small EJ. Randomized controlled trial of early zoledronic acid in men with castration-sensitive prostate cancer and bone metastases: results of CALGB 90202 (alliance). J Clin Oncol. 2014 Apr 10; 32(11):1143-50. PMID: 24590644.
    Citations: 79     Fields:    Translation:HumansCTClinical Trials
  27. Lee RJ, Saylor PJ, Michaelson MD, Rothenberg SM, Smas ME, Miyamoto DT, Gurski CA, Xie W, Maheswaran S, Haber DA, Goldin JG, Smith MR. A dose-ranging study of cabozantinib in men with castration-resistant prostate cancer and bone metastases. Clin Cancer Res. 2013 Jun 01; 19(11):3088-94. PMID: 23553848.
    Citations: 44     Fields:    Translation:HumansCells
  28. Saylor PJ, Smith MR, O'Malley AJ, Keating NL. Androgen-deprivation therapy and risk for biliary disease in men with prostate cancer. Eur Urol. 2014 Mar; 65(3):642-9. PMID: 23428068.
    Citations: 1     Fields:    Translation:Humans
  29. Saylor PJ. Prostate cancer: The androgen receptor remains front and centre. Nat Rev Clin Oncol. 2013 03; 10(3):126-8. PMID: 23381000.
    Citations: 14     Fields:    Translation:Humans
  30. Saylor PJ, Smith MR. Metabolic complications of androgen deprivation therapy for prostate cancer. J Urol. 2013 Jan; 189(1 Suppl):S34-42; discussion S43-4. PMID: 23234628.
    Citations: 52     Fields:    Translation:Humans
  31. Saylor PJ, Armstrong AJ, Fizazi K, Freedland S, Saad F, Smith MR, Tombal B, Pienta K. New and emerging therapies for bone metastases in genitourinary cancers. Eur Urol. 2013 Feb; 63(2):309-20. PMID: 23201471.
    Citations: 15     Fields:    Translation:Humans
  32. Saylor PJ, Mahmood U, Kunawudhi A, Smith MR, Palmer EL, Michaelson MD. Multitargeted tyrosine kinase inhibition produces discordant changes between 99mTc-MDP bone scans and other disease biomarkers: analysis of a phase II study of sunitinib for metastatic castration-resistant prostate cancer. J Nucl Med. 2012 Nov; 53(11):1670-5. PMID: 22984218.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  33. Saylor PJ, Karoly ED, Smith MR. Prospective study of changes in the metabolomic profiles of men during their first three months of androgen deprivation therapy for prostate cancer. Clin Cancer Res. 2012 Jul 01; 18(13):3677-85. PMID: 22589396.
    Citations: 34     Fields:    Translation:HumansCells
  34. Saylor PJ, Escudier B, Michaelson MD. Importance of fibroblast growth factor receptor in neovascularization and tumor escape from antiangiogenic therapy. Clin Genitourin Cancer. 2012 Jun; 10(2):77-83. PMID: 22382009.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  35. Saylor PJ, Karoly ED, Smith MR. Changes in plasma metabolomic profiles during the first 3 months of androgen-deprivation therapy for prostate cancer. J Clin Oncol. 2012 Feb 10; 30(5_suppl):116. PMID: 28143032.
  36. Psutka SP, Olumi AF, Feldman AS, Saylor PJ, Kaufman DS, Lee RJ. Pathologic down-staging and complete pathologic response with gemcitabine and cisplatin neoadjuvant chemotherapy for muscle-invasive urothelial carcinoma of the bladder. J Clin Oncol. 2012 Feb 10; 30(5_suppl):307. PMID: 28143141.
  37. Saylor PJ, Kozak KR, Smith MR, Ancukiewicz MA, Efstathiou JA, Zietman AL, Jain RK, Duda DG. Changes in biomarkers of inflammation and angiogenesis during androgen deprivation therapy for prostate cancer. Oncologist. 2012; 17(2):212-9. PMID: 22302227.
    Citations: 25     Fields:    Translation:Humans
  38. Saylor PJ, Michaelson MD. Should the denosumab metastasis prevention trial change practice for men with nonmetastatic prostate cancer? Oncologist. 2012; 17(2):288-90. PMID: 22267850.
    Citations: 1     Fields:    Translation:Humans
  39. Saylor PJ, Lee RJ, Smith MR. Emerging therapies to prevent skeletal morbidity in men with prostate cancer. J Clin Oncol. 2011 Sep 20; 29(27):3705-14. PMID: 21860001; PMCID: PMC3675709.
    Citations: 37     Fields:    Translation:Humans
  40. Saylor PJ, Morton RA, Hancock ML, Barnette KG, Steiner MS, Smith MR. Factors associated with vertebral fractures in men treated with androgen deprivation therapy for prostate cancer. J Urol. 2011 Aug; 186(2):482-6. PMID: 21679977; PMCID: PMC3669546.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  41. Tabatabaei S, Saylor PJ, Coen J, Dahl DM. Prostate cancer imaging: what surgeons, radiation oncologists, and medical oncologists want to know. AJR Am J Roentgenol. 2011 Jun; 196(6):1263-6. PMID: 21606287.
    Citations: 6     Fields:    Translation:Humans
  42. Saylor PJ. Targeted therapies: denosumab--a new option for solid tumors metastatic to bone. Nat Rev Clin Oncol. 2011 Jun; 8(6):322-4. PMID: 21556026.
    Citations: 2     Fields:    Translation:Humans
  43. Saylor PJ, Keating NL, Freedland SJ, Smith MR. Gonadotropin-releasing hormone agonists and the risks of type 2 diabetes and cardiovascular disease in men with prostate cancer. Drugs. 2011 Feb 12; 71(3):255-61. PMID: 21319864.
    Citations: 4     Fields:    Translation:Humans
  44. Lee RJ, Saylor PJ, Smith MR. Contemporary therapeutic approaches targeting bone complications in prostate cancer. Clin Genitourin Cancer. 2010 Dec 01; 8(1):29-36. PMID: 21208853.
    Citations: 11     Fields:    Translation:HumansCells
  45. Saylor PJ. Re: Fracture types and risk factors in men with prostate cancer on androgen deprivation therapy. Editorial comment. J Urol. 2010 Sep; 184(3):923; author reply 924. PMID: 20643451.
    Citations:    Fields:    
  46. Saylor PJ, Kaufman DS, Michaelson MD, Lee RJ, Smith MR. Application of a fracture risk algorithm to men treated with androgen deprivation therapy for prostate cancer. J Urol. 2010 Jun; 183(6):2200-5. PMID: 20399451; PMCID: PMC2900634.
    Citations: 20     Fields:    Translation:Humans
  47. Lee RJ, Saylor PJ, Smith MR. Treatment and prevention of bone complications from prostate cancer. Bone. 2011 Jan; 48(1):88-95. PMID: 20621630.
    Citations: 35     Fields:    Translation:HumansCells
  48. Saylor PJ, Fogerty AE. Prostate-cancer-associated hypercoagulability: do we need to worry about androgen deprivation? Lancet Oncol. 2010 May; 11(5):406-7. PMID: 20395175.
    Citations:    Fields:    Translation:Humans
  49. Saylor PJ, Smith MR. Adverse effects of androgen deprivation therapy: defining the problem and promoting health among men with prostate cancer. J Natl Compr Canc Netw. 2010 Feb; 8(2):211-23. PMID: 20141678.
    Citations: 23     Fields:    Translation:Humans
  50. Saylor PJ, Smith MR. Bone health and prostate cancer. Prostate Cancer Prostatic Dis. 2010 Mar; 13(1):20-7. PMID: 19901958.
    Citations: 16     Fields:    Translation:HumansCells
  51. Saylor PJ, Keating NL, Smith MR. Prostate cancer survivorship: prevention and treatment of the adverse effects of androgen deprivation therapy. J Gen Intern Med. 2009 Nov; 24 Suppl 2:S389-94. PMID: 19838837.
    Citations: 17     Fields:    Translation:Humans
  52. Saylor PJ, Smith MR. Prostate cancer: How can we improve the health of men who receive ADT? Nat Rev Urol. 2009 Oct; 6(10):529-31. PMID: 19806171.
    Citations: 2     Fields:    Translation:Humans
  53. Saylor PJ, Michaelson MD. New treatments for renal cell carcinoma: targeted therapies. J Natl Compr Canc Netw. 2009 Jun; 7(6):645-56. PMID: 19555586.
    Citations: 8     Fields:    Translation:Humans
  54. Saylor PJ, Smith MR. Metabolic complications of androgen deprivation therapy for prostate cancer. J Urol. 2009 May; 181(5):1998-2006; discussion 2007-8. PMID: 19286225; PMCID: PMC2900631.
    Citations: 76     Fields:    Translation:Humans
  55. Saylor PJ, Reid TR. Tumor lysis syndrome after treatment of a gastrointestinal stromal tumor with the oral tyrosine kinase inhibitor sunitinib. J Clin Oncol. 2007 Aug 10; 25(23):3544-6. PMID: 17687160.
    Citations: 5     Fields:    Translation:Humans
  56. Saylor P, Hanna E, Adams JA. Mutations in the activation loop tyrosine of the oncoprotein v-Fps. Biochemistry. 1998 Dec 22; 37(51):17875-81. PMID: 9922154.
    Citations: 1     Fields:    Translation:AnimalsCells
  57. Saylor P, Wang C, Hirai TJ, Adams JA. A second magnesium ion is critical for ATP binding in the kinase domain of the oncoprotein v-Fps. Biochemistry. 1998 Sep 08; 37(36):12624-30. PMID: 9730835.
    Citations: 8     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.