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profileLauren Jean O'Donnell, Ph.D.

TitleAssistant Professor of Radiology
InstitutionBrigham and Women's Hospital
DepartmentRadiology
AddressBrigham and Womens Hospital
Radiology
75 Francis St
Boston MA 02115
Phone617/875-3326
Fax617/582-6033
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
U01CA199459     (O'DONNELL, LAUREN JEAN)Sep 22, 2015 - Jul 31, 2018
NIH/NCI
Open source diffusion MRI technology for brain cancer research
Role: Principal Investigator

R03NS088301     (O'DONNELL, LAUREN JEAN)Jul 1, 2015 - Jun 30, 2017
NIH/NINDS
Novel diffusion MRI analysis for detection of mild traumatic brain injury
Role: Principal Investigator

R21CA156943     (GOLBY, ALEXANDRA J)Jul 6, 2011 - Jun 30, 2014
NIH/NCI
Rapid Analysis of Intraoperatively Acquired DTI for Identification of Key White M
Role: Co-Principal Investigator

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Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Norton I, Essayed W, Zhang F, Pujol S, Yarmarkovich A, Golby AJ, Kindlmann G, Wasserman D, Estepar RSJ, Rathi Y, Pieper S, Kikinis R, Johnson HJ, Westin CF, O'Donnell LJ. SlicerDMRI: Open Source Diffusion MRI Software for Brain Cancer Research. Cancer Res. 2017 Nov 01; 77(21):e101-e103. PMID: 29092950.
    View in: PubMed
  2. Zhang F, Savadjiev P, Cai W, Song Y, Rathi Y, Tunç B, Parker D, Kapur T, Schultz RT, Makris N, Verma R, O'Donnell LJ. Whole brain white matter connectivity analysis using machine learning: An application to autism. Neuroimage. 2017 Oct 25. PMID: 29079524.
    View in: PubMed
  3. Liao R, Ning L, Chen Z, Rigolo L, Gong S, Pasternak O, Golby AJ, Rathi Y, O'Donnell LJ. Performance of unscented Kalman filter tractography in edema: Analysis of the two-tensor model. Neuroimage Clin. 2017; 15:819-831. PMID: 28725549.
    View in: PubMed
  4. Essayed WI, Zhang F, Unadkat P, Cosgrove GR, Golby AJ, O'Donnell LJ. White matter tractography for neurosurgical planning: A topography-based review of the current state of the art. Neuroimage Clin. 2017; 15:659-672. PMID: 28664037.
    View in: PubMed
  5. Shaffer JJ, Ghayoor A, Long JD, Kim RE, Lourens S, O'Donnell LJ, Westin CF, Rathi Y, Magnotta V, Paulsen JS, Johnson HJ. Longitudinal diffusion changes in prodromal and early HD: Evidence of white-matter tract deterioration. Hum Brain Mapp. 2017 Mar; 38(3):1460-1477. PMID: 28045213.
    View in: PubMed
  6. Jennissen CA, Harland KK, Wetjen K, Hoogerwerf P, O'Donnell L, Denning GM. All-terrain vehicle safety knowledge, riding behaviors and crash experience of Farm Progress Show attendees. J Safety Res. 2017 Feb; 60:71-78. PMID: 28160816.
    View in: PubMed
  7. O'Donnell LJ, Suter Y, Rigolo L, Kahali P, Zhang F, Norton I, Albi A, Olubiyi O, Meola A, Essayed WI, Unadkat P, Ciris PA, Wells WM, Rathi Y, Westin CF, Golby AJ. Automated white matter fiber tract identification in patients with brain tumors. Neuroimage Clin. 2017; 13:138-153. PMID: 27981029.
    View in: PubMed
  8. Kapur T, Pieper S, Fedorov A, Fillion-Robin JC, Halle M, O'Donnell L, Lasso A, Ungi T, Pinter C, Finet J, Pujol S, Jagadeesan J, Tokuda J, Norton I, Estepar RSJ, Gering D, Aerts HJWL, Jakab M, Hata N, Ibanez L, Blezek D, Miller J, Aylward S, Grimson WEL, Fichtinger G, Wells WM, Lorensen WE, Schroeder W, Kikinis R. Increasing the impact of medical image computing using community-based open-access hackathons: The NA-MIC and 3D Slicer experience. Med Image Anal. 2016 Oct; 33:176-180. PMID: 27498015; PMCID: PMC5003088 [Available on 10/01/17].
  9. Fischer DB, Perez DL, Prasad S, Rigolo L, O'Donnell L, Acar D, Meadows ME, Baslet G, Boes AD, Golby AJ, Dworetzky BA. Right inferior longitudinal fasciculus lesions disrupt visual-emotional integration. Soc Cogn Affect Neurosci. 2016 06; 11(6):945-51. PMID: 26940563; PMCID: PMC4884310 [Available on 06/01/17].
  10. Westin CF, Knutsson H, Pasternak O, Szczepankiewicz F, Özarslan E, van Westen D, Mattisson C, Bogren M, O'Donnell LJ, Kubicki M, Topgaard D, Nilsson M. Q-space trajectory imaging for multidimensional diffusion MRI of the human brain. Neuroimage. 2016 Jul 15; 135:345-62. PMID: 26923372; PMCID: PMC4916005 [Available on 07/15/17].
  11. Chen Z, Tie Y, Olubiyi O, Zhang F, Mehrtash A, Rigolo L, Kahali P, Norton I, Pasternak O, Rathi Y, Golby AJ, O'Donnell LJ. Corticospinal tract modeling for neurosurgical planning by tracking through regions of peritumoral edema and crossing fibers using two-tensor unscented Kalman filter tractography. Int J Comput Assist Radiol Surg. 2016 Aug; 11(8):1475-86. PMID: 26762104; PMCID: PMC4942409 [Available on 08/01/17].
  12. Ning L, Laun F, Gur Y, DiBella EV, Deslauriers-Gauthier S, Megherbi T, Ghosh A, Zucchelli M, Menegaz G, Fick R, St-Jean S, Paquette M, Aranda R, Descoteaux M, Deriche R, O'Donnell L, Rathi Y. Sparse Reconstruction Challenge for diffusion MRI: Validation on a physical phantom to determine which acquisition scheme and analysis method to use? Med Image Anal. 2015 Dec; 26(1):316-31. PMID: 26606457.
    View in: PubMed
  13. Chen Z, Tie Y, Olubiyi O, Rigolo L, Mehrtash A, Norton I, Pasternak O, Rathi Y, Golby AJ, O'Donnell LJ. Reconstruction of the arcuate fasciculus for surgical planning in the setting of peritumoral edema using two-tensor unscented Kalman filter tractography. Neuroimage Clin. 2015; 7:815-22. PMID: 26082890; PMCID: PMC4459040.
  14. O'Donnell LJ, Pasternak O. Does diffusion MRI tell us anything about the white matter? An overview of methods and pitfalls. Schizophr Res. 2015 Jan; 161(1):133-41. PMID: 25278106; PMCID: PMC4277728.
  15. O'Donnell LJ, Golby AJ, Westin CF. Fiber clustering versus the parcellation-based connectome. Neuroimage. 2013 Oct 15; 80:283-9. PMID: 23631987; PMCID: PMC3731058.
  16. Wu W, Rigolo L, O'Donnell LJ, Norton I, Shriver S, Golby AJ. Visual pathway study using in vivo diffusion tensor imaging tractography to complement classic anatomy. Neurosurgery. 2012 Mar; 70(1 Suppl Operative):145-56; discussion 156. PMID: 21808220; PMCID: PMC3236807.
  17. O'Donnell LJ, Wells WM, Golby AJ, Westin CF. Unbiased groupwise registration of white matter tractography. Med Image Comput Comput Assist Interv. 2012; 15(Pt 3):123-30. PMID: 23286122; PMCID: PMC3638882.
  18. O'Donnell LJ, Rigolo L, Norton I, Wells WM, Westin CF, Golby AJ. fMRI-DTI modeling via landmark distance atlases for prediction and detection of fiber tracts. Neuroimage. 2012 Mar; 60(1):456-70. PMID: 22155376; PMCID: PMC3423975.
  19. Whitford TJ, Savadjiev P, Kubicki M, O'Donnell LJ, Terry DP, Bouix S, Westin CF, Schneiderman JS, Bobrow L, Rausch AC, Niznikiewicz M, Nestor PG, Pantelis C, Wood SJ, McCarley RW, Shenton ME. Fiber geometry in the corpus callosum in schizophrenia: evidence for transcallosal misconnection. Schizophr Res. 2011 Oct; 132(1):69-74. PMID: 21831601; PMCID: PMC3172336.
  20. O'Donnell LJ, Westin CF. An introduction to diffusion tensor image analysis. Neurosurg Clin N Am. 2011 Apr; 22(2):185-96, viii. PMID: 21435570; PMCID: PMC3163395.
  21. Whitford TJ, Kubicki M, Schneiderman JS, O'Donnell LJ, King R, Alvarado JL, Khan U, Markant D, Nestor PG, Niznikiewicz M, McCarley RW, Westin CF, Shenton ME. Corpus callosum abnormalities and their association with psychotic symptoms in patients with schizophrenia. Biol Psychiatry. 2010 Jul 01; 68(1):70-7. PMID: 20494336; PMCID: PMC2900500.
  22. Propper RE, O'Donnell LJ, Whalen S, Tie Y, Norton IH, Suarez RO, Zollei L, Radmanesh A, Golby AJ. A combined fMRI and DTI examination of functional language lateralization and arcuate fasciculus structure: Effects of degree versus direction of hand preference. Brain Cogn. 2010 Jul; 73(2):85-92. PMID: 20378231; PMCID: PMC2880216.
  23. O'Donnell LJ, Westin CF, Norton I, Whalen S, Rigolo L, Propper R, Golby AJ. The fiber laterality histogram: a new way to measure white matter asymmetry. Med Image Comput Comput Assist Interv. 2010; 13(Pt 2):225-32. PMID: 20879319; PMCID: PMC2999578.
  24. Voineskos AN, O'Donnell LJ, Lobaugh NJ, Markant D, Ameis SH, Niethammer M, Mulsant BH, Pollock BG, Kennedy JL, Westin CF, Shenton ME. Quantitative examination of a novel clustering method using magnetic resonance diffusion tensor tractography. Neuroimage. 2009 Apr 01; 45(2):370-6. PMID: 19159690; PMCID: PMC2646811.
  25. O'Donnell LJ, Westin CF, Golby AJ. Tract-based morphometry for white matter group analysis. Neuroimage. 2009 Apr 15; 45(3):832-44. PMID: 19154790; PMCID: PMC2768362.
  26. Qazi AA, Radmanesh A, O'Donnell L, Kindlmann G, Peled S, Whalen S, Westin CF, Golby AJ. Resolving crossings in the corticospinal tract by two-tensor streamline tractography: Method and clinical assessment using fMRI. Neuroimage. 2009 Aug; 47 Suppl 2:T98-106. PMID: 18657622; PMCID: PMC2746909.
  27. O'Donnell LJ, Westin CF. Automatic tractography segmentation using a high-dimensional white matter atlas. IEEE Trans Med Imaging. 2007 Nov; 26(11):1562-75. PMID: 18041271.
    View in: PubMed
  28. O'Donnell LJ, Westin CF, Golby AJ. Tract-based morphometry. Med Image Comput Comput Assist Interv. 2007; 10(Pt 2):161-8. PMID: 18044565.
    View in: PubMed
  29. Ziyan U, Sabuncu MR, O'Donnell LJ, Westin CF. Nonlinear registration of diffusion MR images based on fiber bundles. Med Image Comput Comput Assist Interv. 2007; 10(Pt 1):351-8. PMID: 18051078.
    View in: PubMed
  30. O'Donnell LJ, Kubicki M, Shenton ME, Dreusicke MH, Grimson WE, Westin CF. A method for clustering white matter fiber tracts. AJNR Am J Neuroradiol. 2006 May; 27(5):1032-6. PMID: 16687538; PMCID: PMC2768142.
  31. O'Donnell L, Westin CF. High-dimensional white matter atlas generation and group analysis. Med Image Comput Comput Assist Interv. 2006; 9(Pt 2):243-51. PMID: 17354778.
    View in: PubMed
  32. Lauren O'Donnell, Steven Haker, and Carl-Fredrik Westin. Image Processing of Diffusion Tensor MRI Data. Advanced Image Processing in Magnetic Resonance Imaging by Luigi Landini, Vincenzo Positano, and Maria Santarelli (Eds.). 2005; 427-450.
  33. Haddad RI, Tishler R, Wirth L, Norris C, Goguen L, Sullivan C, O'Donnell L, Li Y, Posner MR. Rate of complete pathological responses (pCR) to docetaxel/cisplatin/5-fluorouracil (TPF) induction chemotherapy in patients with newly diagnosed, locally advanced squamous cell carcinoma of the head and neck (SCCHN). J Clin Oncol. 2005 Jun; 23(16_suppl):5511. PMID: 27945224.
    View in: PubMed
  34. O'Donnell L, Westin CF. White matter tract clustering and correspondence in populations. Med Image Comput Comput Assist Interv. 2005; 8(Pt 1):140-7. PMID: 16685839.
    View in: PubMed
  35. Gering DT, Nabavi A, Kikinis R, Hata N, O'Donnell LJ, Grimson WE, Jolesz FA, Black PM, Wells WM. An integrated visualization system for surgical planning and guidance using image fusion and an open MR. J Magn Reson Imaging. 2001 Jun; 13(6):967-75. PMID: 11382961.
    View in: PubMed
  36. Yanof, Jeffrey H. Klahr, Paul H. O'Donnell, Lauren. Frameless stereotactic CT scanner with virtual needle display for planning image guided interventional procedures. 2000.
  37. Greaves R, Miller J, O'Donnell L, McLean A, Farthing MJ. Effect of the nitric oxide donor, glyceryl trinitrate, on human gall bladder motility. Gut. 1998 Mar; 42(3):410-3. PMID: 9577350; PMCID: PMC1727023.
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