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Lauren Jean O'Donnell, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01MH119222 (RATHI, YOGESH) Apr 1, 2019 - Jan 31, 2024
    NIH/NIMH
    Harmonizing multi-site diffusion MRI acquisitions for neuroscientific analysis across ages and brain disorders
    Role: Co-Principal Investigator
  2. U01CA199459 (O'DONNELL, LAUREN JEAN) Sep 22, 2015 - Jul 31, 2018
    NIH/NCI
    Open source diffusion MRI technology for brain cancer research
    Role: Principal Investigator
  3. R03NS088301 (O'DONNELL, LAUREN JEAN) Jul 1, 2015 - Jun 30, 2017
    NIH/NINDS
    Novel diffusion MRI analysis for detection of mild traumatic brain injury
    Role: Principal Investigator
  4. R21CA156943 (GOLBY, ALEXANDRA J) Jul 6, 2011 - Jun 30, 2014
    NIH/NCI
    Rapid Analysis of Intraoperatively Acquired DTI for Identification of Key White M
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zhang F, Wu Y, Norton I, Rathi Y, Golby AJ, O'Donnell LJ. Test-retest reproducibility of white matter parcellation using diffusion MRI tractography fiber clustering. Hum Brain Mapp. 2019 Mar 15. PMID: 30875144.
    Citations:    
  2. Lyall AE, Savadjiev P, Del Re EC, Seitz J, O'Donnell LJ, Westin CF, Mesholam-Gately RI, Petryshen T, Wojcik JD, Nestor P, Niznikiewicz M, Goldstein J, Seidman LJ, McCarley RW, Shenton ME, Kubicki M. Utilizing Mutual Information Analysis to Explore the Relationship Between Gray and White Matter Structural Pathologies in Schizophrenia. Schizophr Bull. 2019 Mar 07; 45(2):386-395. PMID: 29618096.
    Citations:    Fields:    
  3. Dalamagkas K, Tsintou M, Rathi Y, O'Donnell LJ, Pasternak O, Gong X, Zhu A, Savadjiev P, Papadimitriou GM, Kubicki M, Yeterian EH, Makris N. Individual variations of the human corticospinal tract and its hand-related motor fibers using diffusion MRI tractography. Brain Imaging Behav. 2019 Jan 08. PMID: 30617788.
    Citations:    Fields:    
  4. Stojanovski S, Felsky D, Viviano JD, Shahab S, Bangali R, Burton CL, Devenyi GA, O'Donnell LJ, Szatmari P, Chakravarty MM, Ameis S, Schachar R, Voineskos AN, Wheeler AL. Polygenic Risk and Neural Substrates of Attention-Deficit/Hyperactivity Disorder Symptoms in Youths With a History of Mild Traumatic Brain Injury. Biol Psychiatry. 2019 Mar 01; 85(5):408-416. PMID: 30119875.
    Citations:    Fields:    
  5. Wu Y, Zhang F, Makris N, Ning Y, Norton I, She S, Peng H, Rathi Y, Feng Y, Wu H, O'Donnell LJ. Investigation into local white matter abnormality in emotional processing and sensorimotor areas using an automatically annotated fiber clustering in major depressive disorder. Neuroimage. 2018 11 01; 181:16-29. PMID: 29890329.
    Citations:    Fields:    Translation:HumansCells
  6. Zhang F, Wu Y, Norton I, Rigolo L, Rathi Y, Makris N, O'Donnell LJ. An anatomically curated fiber clustering white matter atlas for consistent white matter tract parcellation across the lifespan. Neuroimage. 2018 10 01; 179:429-447. PMID: 29920375.
    Citations:    Fields:    
  7. Hong Y, O'Donnell LJ, Savadjiev P, Zhang F, Wassermann D, Pasternak O, Johnson H, Paulsen J, Vonsattel JP, Makris N, Westin CF, Rathi Y. Genetic load determines atrophy in hand cortico-striatal pathways in presymptomatic Huntington's disease. Hum Brain Mapp. 2018 10; 39(10):3871-3883. PMID: 29797744.
    Citations:    Fields:    
  8. Sydnor VJ, Rivas-Grajales AM, Lyall AE, Zhang F, Bouix S, Karmacharya S, Shenton ME, Westin CF, Makris N, Wassermann D, O'Donnell LJ, Kubicki M. A comparison of three fiber tract delineation methods and their impact on white matter analysis. Neuroimage. 2018 09; 178:318-331. PMID: 29787865.
    Citations:    Fields:    
  9. Gong S, Zhang F, Norton I, Essayed WI, Unadkat P, Rigolo L, Pasternak O, Rathi Y, Hou L, Golby AJ, O'Donnell LJ. Free water modeling of peritumoral edema using multi-fiber tractography: Application to tracking the arcuate fasciculus for neurosurgical planning. PLoS One. 2018; 13(5):e0197056. PMID: 29746544.
    Citations:    Fields:    Translation:Humans
  10. Zhang F, Wu W, Ning L, McAnulty G, Waber D, Gagoski B, Sarill K, Hamoda HM, Song Y, Cai W, Rathi Y, O'Donnell LJ. Suprathreshold fiber cluster statistics: Leveraging white matter geometry to enhance tractography statistical analysis. Neuroimage. 2018 05 01; 171:341-354. PMID: 29337279.
    Citations:    Fields:    Translation:Humans
  11. Albi A, Meola A, Zhang F, Kahali P, Rigolo L, Tax CMW, Ciris PA, Essayed WI, Unadkat P, Norton I, Rathi Y, Olubiyi O, Golby AJ, O'Donnell LJ. Image Registration to Compensate for EPI Distortion in Patients with Brain Tumors: An Evaluation of Tract-Specific Effects. J Neuroimaging. 2018 Mar; 28(2):173-182. PMID: 29319208.
    Citations: 1     Fields:    
  12. O'Donnell LJ, Daducci A, Wassermann D, Lenglet C. Advances in computational and statistical diffusion MRI. NMR Biomed. 2019 Apr; 32(4):e3805. PMID: 29134716.
    Citations: 1     Fields:    
  13. Stefanik L, Erdman L, Ameis SH, Foussias G, Mulsant BH, Behdinan T, Goldenberg A, O'Donnell LJ, Voineskos AN. Brain-Behavior Participant Similarity Networks Among Youth and Emerging Adults with Schizophrenia Spectrum, Autism Spectrum, or Bipolar Disorder and Matched Controls. Neuropsychopharmacology. 2018 04; 43(5):1180-1188. PMID: 29105664.
    Citations: 1     Fields:    
  14. Norton I, Essayed W, Zhang F, Pujol S, Yarmarkovich A, Golby AJ, Kindlmann G, Wassermann D, Estepar RSJ, Rathi Y, Pieper S, Kikinis R, Johnson HJ, Westin CF, O'Donnell LJ. SlicerDMRI: Open Source Diffusion MRI Software for Brain Cancer Research. Cancer Res. 2017 11 01; 77(21):e101-e103. PMID: 29092950.
    Citations: 2     Fields:    Translation:Humans
  15. Zhang F, Savadjiev P, Cai W, Song Y, Rathi Y, Tunç B, Parker D, Kapur T, Schultz RT, Makris N, Verma R, O'Donnell LJ. Whole brain white matter connectivity analysis using machine learning: An application to autism. Neuroimage. 2018 05 15; 172:826-837. PMID: 29079524.
    Citations: 3     Fields:    Translation:Humans
  16. Liao R, Ning L, Chen Z, Rigolo L, Gong S, Pasternak O, Golby AJ, Rathi Y, O'Donnell LJ. Performance of unscented Kalman filter tractography in edema: Analysis of the two-tensor model. Neuroimage Clin. 2017; 15:819-831. PMID: 28725549.
    Citations:    Fields:    Translation:HumansCells
  17. Essayed WI, Zhang F, Unadkat P, Cosgrove GR, Golby AJ, O'Donnell LJ. White matter tractography for neurosurgical planning: A topography-based review of the current state of the art. Neuroimage Clin. 2017; 15:659-672. PMID: 28664037.
    Citations: 9     Fields:    Translation:Humans
  18. Shaffer JJ, Ghayoor A, Long JD, Kim RE, Lourens S, O'Donnell LJ, Westin CF, Rathi Y, Magnotta V, Paulsen JS, Johnson HJ. Longitudinal diffusion changes in prodromal and early HD: Evidence of white-matter tract deterioration. Hum Brain Mapp. 2017 03; 38(3):1460-1477. PMID: 28045213.
    Citations: 4     Fields:    Translation:HumansCells
  19. Jennissen CA, Harland KK, Wetjen K, Hoogerwerf P, O'Donnell L, Denning GM. All-terrain vehicle safety knowledge, riding behaviors and crash experience of Farm Progress Show attendees. J Safety Res. 2017 02; 60:71-78. PMID: 28160816.
    Citations: 1     Fields:    Translation:Humans
  20. O'Donnell LJ, Suter Y, Rigolo L, Kahali P, Zhang F, Norton I, Albi A, Olubiyi O, Meola A, Essayed WI, Unadkat P, Ciris PA, Wells WM, Rathi Y, Westin CF, Golby AJ. Automated white matter fiber tract identification in patients with brain tumors. Neuroimage Clin. 2017; 13:138-153. PMID: 27981029.
    Citations: 7     Fields:    Translation:Humans
  21. Kapur T, Pieper S, Fedorov A, Fillion-Robin JC, Halle M, O'Donnell L, Lasso A, Ungi T, Pinter C, Finet J, Pujol S, Jagadeesan J, Tokuda J, Norton I, Estepar RSJ, Gering D, Aerts HJWL, Jakab M, Hata N, Ibanez L, Blezek D, Miller J, Aylward S, Grimson WEL, Fichtinger G, Wells WM, Lorensen WE, Schroeder W, Kikinis R. Increasing the impact of medical image computing using community-based open-access hackathons: The NA-MIC and 3D Slicer experience. Med Image Anal. 2016 10; 33:176-180. PMID: 27498015.
    Citations: 3     Fields:    Translation:Humans
  22. Fischer DB, Perez DL, Prasad S, Rigolo L, O'Donnell L, Acar D, Meadows ME, Baslet G, Boes AD, Golby AJ, Dworetzky BA. Right inferior longitudinal fasciculus lesions disrupt visual-emotional integration. Soc Cogn Affect Neurosci. 2016 06; 11(6):945-51. PMID: 26940563.
    Citations: 2     Fields:    Translation:Humans
  23. Westin CF, Knutsson H, Pasternak O, Szczepankiewicz F, Özarslan E, van Westen D, Mattisson C, Bogren M, O'Donnell LJ, Kubicki M, Topgaard D, Nilsson M. Q-space trajectory imaging for multidimensional diffusion MRI of the human brain. Neuroimage. 2016 07 15; 135:345-62. PMID: 26923372.
    Citations: 12     Fields:    Translation:Humans
  24. Chen Z, Tie Y, Olubiyi O, Zhang F, Mehrtash A, Rigolo L, Kahali P, Norton I, Pasternak O, Rathi Y, Golby AJ, O'Donnell LJ. Corticospinal tract modeling for neurosurgical planning by tracking through regions of peritumoral edema and crossing fibers using two-tensor unscented Kalman filter tractography. Int J Comput Assist Radiol Surg. 2016 Aug; 11(8):1475-86. PMID: 26762104; PMCID: PMC4942409.
    Citations: 7     Fields:    Translation:Humans
  25. Ning L, Laun F, Gur Y, DiBella EV, Deslauriers-Gauthier S, Megherbi T, Ghosh A, Zucchelli M, Menegaz G, Fick R, St-Jean S, Paquette M, Aranda R, Descoteaux M, Deriche R, O'Donnell L, Rathi Y. Sparse Reconstruction Challenge for diffusion MRI: Validation on a physical phantom to determine which acquisition scheme and analysis method to use? Med Image Anal. 2015 Dec; 26(1):316-31. PMID: 26606457.
    Citations: 8     Fields:    Translation:Humans
  26. Chen Z, Tie Y, Olubiyi O, Rigolo L, Mehrtash A, Norton I, Pasternak O, Rathi Y, Golby AJ, O'Donnell LJ. Reconstruction of the arcuate fasciculus for surgical planning in the setting of peritumoral edema using two-tensor unscented Kalman filter tractography. Neuroimage Clin. 2015; 7:815-22. PMID: 26082890; PMCID: PMC4459040.
    Citations: 8     Fields:    Translation:HumansCellsCTClinical Trials
  27. O'Donnell LJ, Pasternak O. Does diffusion MRI tell us anything about the white matter? An overview of methods and pitfalls. Schizophr Res. 2015 Jan; 161(1):133-41. PMID: 25278106; PMCID: PMC4277728.
    Citations: 14     Fields:    Translation:HumansCells
  28. O'Donnell LJ, Golby AJ, Westin CF. Fiber clustering versus the parcellation-based connectome. Neuroimage. 2013 Oct 15; 80:283-9. PMID: 23631987; PMCID: PMC3731058.
    Citations: 19     Fields:    Translation:HumansCells
  29. Wu W, Rigolo L, O'Donnell LJ, Norton I, Shriver S, Golby AJ. Visual pathway study using in vivo diffusion tensor imaging tractography to complement classic anatomy. Neurosurgery. 2012 Mar; 70(1 Suppl Operative):145-56; discussion 156. PMID: 21808220; PMCID: PMC3236807.
    Citations: 12     Fields:    Translation:Humans
  30. O'Donnell LJ, Wells WM, Golby AJ, Westin CF. Unbiased groupwise registration of white matter tractography. Med Image Comput Comput Assist Interv. 2012; 15(Pt 3):123-30. PMID: 23286122; PMCID: PMC3638882.
    Citations: 5     Fields:    Translation:HumansCells
  31. O'Donnell LJ, Rigolo L, Norton I, Wells WM, Westin CF, Golby AJ. fMRI-DTI modeling via landmark distance atlases for prediction and detection of fiber tracts. Neuroimage. 2012 Mar; 60(1):456-70. PMID: 22155376; PMCID: PMC3423975.
    Citations: 9     Fields:    Translation:Humans
  32. Whitford TJ, Savadjiev P, Kubicki M, O'Donnell LJ, Terry DP, Bouix S, Westin CF, Schneiderman JS, Bobrow L, Rausch AC, Niznikiewicz M, Nestor PG, Pantelis C, Wood SJ, McCarley RW, Shenton ME. Fiber geometry in the corpus callosum in schizophrenia: evidence for transcallosal misconnection. Schizophr Res. 2011 Oct; 132(1):69-74. PMID: 21831601; PMCID: PMC3172336.
    Citations: 7     Fields:    Translation:HumansCells
  33. O'Donnell LJ, Westin CF. An introduction to diffusion tensor image analysis. Neurosurg Clin N Am. 2011 Apr; 22(2):185-96, viii. PMID: 21435570; PMCID: PMC3163395.
    Citations: 29     Fields:    Translation:HumansCells
  34. Whitford TJ, Kubicki M, Schneiderman JS, O'Donnell LJ, King R, Alvarado JL, Khan U, Markant D, Nestor PG, Niznikiewicz M, McCarley RW, Westin CF, Shenton ME. Corpus callosum abnormalities and their association with psychotic symptoms in patients with schizophrenia. Biol Psychiatry. 2010 Jul 01; 68(1):70-7. PMID: 20494336; PMCID: PMC2900500.
    Citations: 60     Fields:    Translation:HumansCells
  35. Propper RE, O'Donnell LJ, Whalen S, Tie Y, Norton IH, Suarez RO, Zollei L, Radmanesh A, Golby AJ. A combined fMRI and DTI examination of functional language lateralization and arcuate fasciculus structure: Effects of degree versus direction of hand preference. Brain Cogn. 2010 Jul; 73(2):85-92. PMID: 20378231; PMCID: PMC2880216.
    Citations: 25     Fields:    Translation:Humans
  36. O'Donnell LJ, Westin CF, Norton I, Whalen S, Rigolo L, Propper R, Golby AJ. The fiber laterality histogram: a new way to measure white matter asymmetry. Med Image Comput Comput Assist Interv. 2010; 13(Pt 2):225-32. PMID: 20879319; PMCID: PMC2999578.
    Citations: 2     Fields:    Translation:HumansCells
  37. Voineskos AN, O'Donnell LJ, Lobaugh NJ, Markant D, Ameis SH, Niethammer M, Mulsant BH, Pollock BG, Kennedy JL, Westin CF, Shenton ME. Quantitative examination of a novel clustering method using magnetic resonance diffusion tensor tractography. Neuroimage. 2009 Apr 01; 45(2):370-6. PMID: 19159690; PMCID: PMC2646811.
    Citations: 20     Fields:    Translation:HumansCells
  38. O'Donnell LJ, Westin CF, Golby AJ. Tract-based morphometry for white matter group analysis. Neuroimage. 2009 Apr 15; 45(3):832-44. PMID: 19154790; PMCID: PMC2768362.
    Citations: 53     Fields:    Translation:Humans
  39. Qazi AA, Radmanesh A, O'Donnell L, Kindlmann G, Peled S, Whalen S, Westin CF, Golby AJ. Resolving crossings in the corticospinal tract by two-tensor streamline tractography: Method and clinical assessment using fMRI. Neuroimage. 2009 Aug; 47 Suppl 2:T98-106. PMID: 18657622; PMCID: PMC2746909.
    Citations: 46     Fields:    Translation:Humans
  40. O'Donnell LJ, Westin CF. Automatic tractography segmentation using a high-dimensional white matter atlas. IEEE Trans Med Imaging. 2007 Nov; 26(11):1562-75. PMID: 18041271.
    Citations: 81     Fields:    Translation:HumansCells
  41. O'Donnell LJ, Westin CF, Golby AJ. Tract-based morphometry. Med Image Comput Comput Assist Interv. 2007; 10(Pt 2):161-8. PMID: 18044565.
    Citations: 5     Fields:    Translation:HumansCells
  42. Ziyan U, Sabuncu MR, O'Donnell LJ, Westin CF. Nonlinear registration of diffusion MR images based on fiber bundles. Med Image Comput Comput Assist Interv. 2007; 10(Pt 1):351-8. PMID: 18051078.
    Citations: 17     Fields:    Translation:Cells
  43. O'Donnell LJ, Kubicki M, Shenton ME, Dreusicke MH, Grimson WE, Westin CF. A method for clustering white matter fiber tracts. AJNR Am J Neuroradiol. 2006 May; 27(5):1032-6. PMID: 16687538.
    Citations: 38     Fields:    Translation:Humans
  44. O'Donnell L, Westin CF. High-dimensional white matter atlas generation and group analysis. Med Image Comput Comput Assist Interv. 2006; 9(Pt 2):243-51. PMID: 17354778.
    Citations: 6     Fields:    Translation:HumansCells
  45. Lauren O'Donnell, Steven Haker, and Carl-Fredrik Westin. Image Processing of Diffusion Tensor MRI Data. Advanced Image Processing in Magnetic Resonance Imaging by Luigi Landini, Vincenzo Positano, and Maria Santarelli (Eds.). 2005; 427-450.
  46. Haddad RI, Tishler R, Wirth L, Norris C, Goguen L, Sullivan C, O'Donnell L, Li Y, Posner MR. Rate of complete pathological responses (pCR) to docetaxel/cisplatin/5-fluorouracil (TPF) induction chemotherapy in patients with newly diagnosed, locally advanced squamous cell carcinoma of the head and neck (SCCHN). J Clin Oncol. 2005 Jun; 23(16_suppl):5511. PMID: 27945224.
    Citations:    
  47. O'Donnell L, Westin CF. White matter tract clustering and correspondence in populations. Med Image Comput Comput Assist Interv. 2005; 8(Pt 1):140-7. PMID: 16685839.
    Citations: 14     Fields:    Translation:HumansCells
  48. Gering DT, Nabavi A, Kikinis R, Hata N, O'Donnell LJ, Grimson WE, Jolesz FA, Black PM, Wells WM. An integrated visualization system for surgical planning and guidance using image fusion and an open MR. J Magn Reson Imaging. 2001 Jun; 13(6):967-75. PMID: 11382961.
    Citations: 77     Fields:    Translation:Humans
  49. Yanof, Jeffrey H. Klahr, Paul H. O'Donnell, Lauren. Frameless stereotactic CT scanner with virtual needle display for planning image guided interventional procedures. 2000.
  50. Greaves R, Miller J, O'Donnell L, McLean A, Farthing MJ. Effect of the nitric oxide donor, glyceryl trinitrate, on human gall bladder motility. Gut. 1998 Mar; 42(3):410-3. PMID: 9577350; PMCID: PMC1727023.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.