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Uzma Shah, M.B.,B.S., M.B.

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Overview
Dr Shah trained in medicine at Dow Medical College with a residency in Pediatrics in Chicago and fellowship at Children's Hospital and Massachusetts General Hospital, Boston. Her work has included research in mucosal immunology, viral hepatitis and cystic fibrosis.

She was the Chief of the Division of Pediatric Gastroenterology at the Aga Khan University Hospital in Pakistan. In collaboration with the Ministry of Health Pakistan, World Health Organization and UNICEF, she has contributed extensively to major regional development in Child Health and Global Health Programs against Viral Hepatitis.
She worked as the Director of Research at Harvard Medical School Dubai, with a mandate to develop the Research Master Plan for the region and served as an academic lead for the development of a 300 bed University Hospital and on the steering committee for a 200 bed Pediatric facility. She led the development of Pediatrics and Pediatric Gastroenterology at the Dubai Medical Suites.

She is currently an Associate Professor at HMS, Clinical Chief , Pediatric Gastroenterology, the Chief of the Hepatobiliary and Pancreas Program in Pediatrics at Mass General Hospital for Children (MGHfC) and the Medical Director of the Pediatric Liver Transplant Program.

Her research interests include viral hepatitis, inherited metabolic liver disease, liver transplantation , chronic pancreatitis and Global Health.

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Laborda TJ, Ricciuto A, Aumar M, Carman N, DiGuglielmo M, Draijer LG, Furuya KN, Gupta N, Koot BGP, Loomes KM, Lytvyak E, Martinez M, Miloh T, Montano-Loza AJ, Perito ER, Sathya P, Shah U, Shteyer E, Singh R, Taylor A, Valentino PL, Vitola B, Zerofsky M, Zizzo A, Deneau MR. Vedolizumab Therapy in Children With Primary Sclerosing Cholangitis: Data From the Pediatric PSC Consortium. J Pediatr Gastroenterol Nutr. 2020 Jul 28. PMID: 32740528.
    Citations:    
  2. Dike CR, Zimmerman B, Zheng Y, Wilschanski M, Werlin SL, Troendle D, Shah U, Schwarzenberg SJ, Pohl J, Perito ER, Ooi CY, Nathan JD, Morinville VD, McFerron B, Mascarenhas M, Maqbool A, Liu Q, Lin TK, Husain SZ, Heyman MB, Gonska T, Giefer MJ, Gariepy CE, Fishman DS, Bellin M, Barth B, Abu-El-Haija M, Lowe ME, Uc A. Clinical and Practice Variations in Pediatric Acute Recurrent or Chronic Pancreatitis: Report From the INSPPIRE Study. J Pediatr Gastroenterol Nutr. 2020 Jul; 71(1):112-118. PMID: 32079978.
    Citations:    
  3. Deneau MR, Mack C, Perito ER, Ricciuto A, Valentino PL, Amin M, Amir AZ, Aumar M, Auth M, Broderick A, DiGuglielmo M, Draijer LG, Tavares Fagundes ED, El-Matary W, Ferrari F, Furuya KN, Gupta N, Hochberg JT, Homan M, Horslen S, Iorio R, Jensen MK, Jonas MM, Kamath BM, Kerkar N, Kim KM, Kolho KL, Koot BG, Laborda TJ, Lee CK, Loomes KM, Martinez M, Miethke A, Miloh T, Mogul D, Mohammed S, Mohan P, Moroz S, Ovchinsky N, Palle S, Papadopoulou A, Rao G, Rodrigues Ferreira A, Sathya P, Schwarz KB, Shah U, Shteyer E, Singh R, Smolka V, Soufi N, Tanaka A, Varier R, Vitola B, Woynarowski M, Zerofsky M, Zizzo A, Guthery SL. The Sclerosing Cholangitis Outcomes in Pediatrics (SCOPE) index: a prognostic tool for children. Hepatology. 2020 May 28. PMID: 32464706.
    Citations:    
  4. El-Matary W, Guthery SL, Amir AZ, DiGuglielmo M, Draijer LG, Furuya KN, Gupta N, Hochberg JT, Horslen S, Kerkar N, Koot BGP, Laborda TJ, Loomes KM, Mack C, Martinez M, Miethke A, Miloh T, Mogul D, Mohammed S, Moroz S, Ovchinsky N, Perito ER, Rao G, Ricciuto A, Sathya P, Schwarz KB, Shah U, Singh R, Soufi N, Valentino PL, Zizzo A, Deneau MR. Colorectal Dysplasia and Cancer in Pediatric-Onset Ulcerative Colitis Associated With Primary Sclerosing Cholangitis. Clin Gastroenterol Hepatol. 2020 Apr 29. PMID: 32360820.
    Citations:    
  5. Abu-El-Haija M, Lowe M, Barth B, Bellin MD, Fishman DS, Freedman S, Gariepy C, Giefer MJ, Gonska T, Heyman MB, Himes R, Husain S, Lin TK, Liu Q, Mascarenhas MR, Maqbool A, McFerron B, Morinville V, Nathan J, Ooi CY, Perito E, Pohl JF, Schwarzenberg SJ, Shah U, Troendle D, Werlin S, Wilschanski M, Zimmerman B, Uc A. Pediatric chronic pancreatitis without prior acute or acute recurrent pancreatitis: A report from the INSPPIRE consortium. Pancreatology. 2020 06; 20(4):781-784. PMID: 32332002.
    Citations:    
  6. Cuenca AG, Hardy S, Shah U, Lawlor D, Ordulu Z, Sierra Velez D, Olshan K, Butler W, Yeh H. Pediatric liver transplant following near catastrophic head bleed: Lessons learned. Pediatr Transplant. 2020 03; 24(2):e13646. PMID: 31960553.
    Citations:    
  7. Perito ER, Palermo TM, Pohl JF, Mascarenhas M, Abu-El-Haija M, Barth B, Bellin MD, Fishman DS, Freedman S, Gariepy C, Giefer M, Gonska T, Heyman MB, Himes RW, Husain SZ, Lin T, Liu Q, Maqbool A, McFerron B, Morinville VD, Nathan JD, Ooi CY, Rhee S, Schwarzenberg SJ, Shah U, Troendle DM, Werlin S, Wilschanski M, Zheng Y, Zimmerman MB, Lowe M, Uc A. Factors Associated With Frequent Opioid Use in Children With Acute Recurrent and Chronic Pancreatitis. J Pediatr Gastroenterol Nutr. 2020 01; 70(1):106-114. PMID: 31567889.
    Citations:    
  8. Palermo TM, Murray C, Aalfs H, Abu-El-Haija M, Barth B, Bellin MD, Ellery K, Fishman DS, Gariepy CE, Giefer MJ, Goday P, Gonska T, Heyman MB, Husain SZ, Lin TK, Liu QY, Mascarenhas MR, Maqbool A, McFerron B, Morinville VD, Nathan JD, Ooi CY, Perito ER, Pohl JF, Schwarzenberg SJ, Sellers ZM, Serrano J, Shah U, Troendle D, Zheng Y, Yuan Y, Lowe M, Uc A. Web-based cognitive-behavioral intervention for pain in pediatric acute recurrent and chronic pancreatitis: Protocol of a multicenter randomized controlled trial from the study of chronic pancreatitis, diabetes and pancreatic cancer (CPDPC). Contemp Clin Trials. 2020 01; 88:105898. PMID: 31756383.
    Citations:    
  9. Bellin MD, Lowe M, Zimmerman MB, Wilschanski M, Werlin S, Troendle DM, Shah U, Schwarzenberg SJ, Pohl JF, Perito E, Ooi CY, Nathan JD, Morinville VD, McFerron BA, Mascarenhas MR, Maqbool A, Liu Q, Lin TK, Husain SZ, Himes R, Heyman MB, Gonska T, Giefer MJ, Gariepy CE, Freedman SD, Fishman DS, Barth B, Abu-El-Haija M, Uc A. Diabetes Mellitus in Children with Acute Recurrent and Chronic Pancreatitis: Data From the INternational Study Group of Pediatric Pancreatitis: In Search for a CuRE Cohort. J Pediatr Gastroenterol Nutr. 2019 11; 69(5):599-606. PMID: 31651815.
    Citations:    
  10. Jafri RZ, McNamara EA, Snyder EA, Shah U, Singh I, Hayes FJ, Lin AE, Levitsky LL. Further Delineation of Liver Involvement in Girls and Women with Turner Syndrome: Case Report of a 2-Year-Old with Liver Dysfunction and Review of Patients Followed in the MassGeneral Hospital Turner Syndrome Clinic. Horm Res Paediatr. 2019; 92(5):328-334. PMID: 31563903.
    Citations:    
  11. Bellin MD, Lowe M, Zimmerman MB, Wilschanski M, Werlin S, Troendle DM, Shah U, Schwarzenberg SJ, Pohl JF, Perito E, Ooi CY, Nathan JD, Morinville VD, McFerron BA, Mascarenhas MR, Maqbool A, Liu Q, Lin TK, Husain SZ, Himes R, Heyman MB, Gonska T, Giefer MJ, Gariepy CE, Freedman SD, Fishman DS, Barth B, Abu-El-Haija M, Uc A. Diabetes Mellitus in Children with Acute Recurrent and Chronic Pancreatitis: Data from the INSPPIRE Cohort. J Pediatr Gastroenterol Nutr. 2019 Aug 27. PMID: 31460885.
    Citations:    
  12. Liu QY, Abu-El-Haija M, Husain SZ, Barth B, Bellin M, Fishman DS, Freedman SD, Gariepy CE, Giefer MJ, Gonska T, Heyman MB, Himes R, Lin TK, Maqbool A, Mascarenhas M, McFerron BA, Morinville VD, Nathan JD, Ooi CY, Perito ER, Pohl JF, Rhee S, Schwarzenberg SJ, Shah U, Troendle D, Werlin SL, Wilschanski M, Zimmerman MB, Lowe ME, Uc A. Risk Factors for Rapid Progression From Acute Recurrent to Chronic Pancreatitis in Children: Report From INSPPIRE. J Pediatr Gastroenterol Nutr. 2019 08; 69(2):206-211. PMID: 31136562.
    Citations:    
  13. Lin TK, Abu-El-Haija M, Nathan JD, Palermo JP, Barth B, Bellin M, Fishman DS, Freedman SD, Gariepy CE, Giefer MJ, Gonska T, Heyman MB, Himes R, Husain SZ, Liu Q, Maqbool A, Mascarenhas M, McFerron B, Morinville VD, Ooi CY, Perito E, Pohl JF, Rhee S, Schwarzenberg SJ, Shah U, Troendle D, Werlin SL, Wilschanski M, Zimmerman MB, Lowe ME, Uc A. Pancreas Divisum in Pediatric Acute Recurrent and Chronic Pancreatitis: Report From INSPPIRE. J Clin Gastroenterol. 2019 07; 53(6):e232-e238. PMID: 29864067.
    Citations: 1     Fields:    
  14. Schwarzenberg SJ, Uc A, Zimmerman B, Wilschanski M, Wilcox CM, Whitcomb DC, Werlin SL, Troendle D, Tang G, Slivka A, Singh VK, Sherman S, Shah U, Sandhu BS, Romagnuolo J, Rhee S, Pohl JF, Perito ER, Ooi CY, Nathan JD, Muniraj T, Morinville VD, McFerron B, Mascarenhas M, Maqbool A, Liu Q, Lin TK, Lewis M, Husain SZ, Himes R, Heyman MB, Guda N, Gonska T, Giefer MJ, Gelrud A, Gariepy CE, Gardner TB, Freedman SD, Forsmark CE, Fishman DS, Cote GA, Conwell D, Brand RE, Bellin M, Barth B, Banks PA, Anderson MA, Amann ST, Alkaade S, Abu-El-Haija M, Abberbock JN, Lowe ME, Yadav D. Chronic Pancreatitis: Pediatric and Adult Cohorts Show Similarities in Disease Progress Despite Different Risk Factors. J Pediatr Gastroenterol Nutr. 2019 04; 68(4):566-573. PMID: 30897605.
    Citations:    
  15. Deneau M, Perito E, Ricciuto A, Gupta N, Kamath BM, Palle S, Vitola B, Smolka V, Ferrari F, Amir AZ, Miloh T, Papadopoulou A, Mohan P, Mack C, Kolho KL, Iorio R, El-Matary W, Venkat V, Chan A, Saubermann L, Valentino PL, Shah U, Miethke A, Lin H, Jensen MK. Ursodeoxycholic Acid Therapy in Pediatric Primary Sclerosing Cholangitis: Predictors of Gamma Glutamyltransferase Normalization and Favorable Clinical Course. J Pediatr. 2019 06; 209:92-96.e1. PMID: 30878206.
    Citations:    
  16. Uc A, Perito ER, Pohl JF, Shah U, Abu-El-Haija M, Barth B, Bellin MD, Ellery KM, Fishman DS, Gariepy CE, Giefer MJ, Gonska T, Heyman MB, Himes RW, Husain SZ, Maqbool A, Mascarenhas MR, McFerron BA, Morinville VD, Lin TK, Liu QY, Nathan JD, Rhee SJ, Ooi CY, Sellers ZM, Schwarzenberg SJ, Serrano J, Troendle DM, Werlin SL, Wilschanski M, Zheng Y, Yuan Y, Lowe ME. INternational Study Group of Pediatric Pancreatitis: In Search for a CuRE Cohort Study: Design and Rationale for INSPPIRE 2 From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas. 2018 Nov/Dec; 47(10):1222-1228. PMID: 30325861.
    Citations:    Fields:    
  17. Uc A, Zimmerman MB, Wilschanski M, Werlin SL, Troendle D, Shah U, Schwarzenberg SJ, Rhee S, Pohl JF, Perito ER, Palermo JJ, Ooi CY, Liu Q, Lin TK, Morinville VD, McFerron BA, Husain SZ, Himes R, Heyman MB, Gonska T, Giefer MJ, Gariepy CE, Freedman SD, Fishman DS, Bellin MD, Barth B, Abu-El-Haija M, Lowe ME. Impact of Obesity on Pediatric Acute Recurrent and Chronic Pancreatitis. Pancreas. 2018 09; 47(8):967-973. PMID: 30059474.
    Citations:    Fields:    Translation:Humans
  18. Scheers I, Palermo JJ, Freedman S, Wilschanski M, Shah U, Abu-El-Haija M, Barth B, Fishman DS, Gariepy C, Giefer MJ, Heyman MB, Himes RW, Husain SZ, Lin TK, Liu Q, Lowe M, Mascarenhas M, Morinville V, Ooi CY, Perito ER, Piccoli DA, Pohl JF, Schwarzenberg SJ, Troendle D, Werlin S, Zimmerman B, Uc A, Gonska T. Recommendations for Diagnosis and Management of Autoimmune Pancreatitis in Childhood: Consensus From INSPPIRE. J Pediatr Gastroenterol Nutr. 2018 08; 67(2):232-236. PMID: 29746340.
    Citations: 1     Fields:    
  19. Shah U, Goldstein AM, Gee MS, Deshpande V. Case 24-2017. An 8-Month-Old Girl with Fever and an Abdominal Mass. N Engl J Med. 2017 Aug 10; 377(6):574-582. PMID: 28792868.
    Citations:    Fields:    Translation:HumansCells
  20. Scheers I, Palermo JJ, Freedman S, Wilschanski M, Shah U, Abu-El-Haija M, Barth B, Fishman DS, Gariepy C, Giefer MJ, Heyman MB, Himes RW, Husain SZ, Lin TK, Liu Q, Lowe M, Mascarenhas M, Morinville V, Ooi CY, Perito ER, Piccoli DA, Pohl JF, Schwarzenberg SJ, Troendle D, Werlin S, Zimmerman B, Uc A, Gonska T. Autoimmune Pancreatitis in Children: Characteristic Features, Diagnosis, and Management. Am J Gastroenterol. 2017 Oct; 112(10):1604-1611. PMID: 28374818.
    Citations: 4     Fields:    Translation:Humans
  21. Walter JE, Armanios M, Shah U, Friedmann AM, Spitzer T, Sharatz SM, Hagen C. CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 41-2015. A 14-Year-Old Boy with Immune and Liver Abnormalities. N Engl J Med. 2015 Dec 31; 373(27):2664-76. PMID: 26716919.
    Citations: 2     Fields:    Translation:HumansCells
  22. Dhyani M, Gee MS, Misdraji J, Israel EJ, Shah U, Samir AE. Feasibility study for assessing liver fibrosis in paediatric and adolescent patients using real-time shear wave elastography. J Med Imaging Radiat Oncol. 2015 Dec; 59(6):687-94; quiz 751. PMID: 26503488.
    Citations: 3     Fields:    Translation:Humans
  23. Roumiantsev S, Shah U, Westra SJ, Misdraji J. CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 20-2015. A Newborn Girl with Hypotension, Coagulopathy, Anemia, and Hyperbilirubinemia. N Engl J Med. 2015 Jun 25; 372(26):2542-53. PMID: 26107055.
    Citations:    Fields:    Translation:Humans
  24. Pollack SF, Geffrey AL, Thiele EA, Shah U. Primary intestinal lymphangiectasia treated with rapamycin in a child with tuberous sclerosis complex (TSC). Am J Med Genet A. 2015 Sep; 167A(9):2209-12. PMID: 25943403.
    Citations: 2     Fields:    Translation:Humans
  25. Tanpowpong P, Sabharwal S, Shah U. Fever, jaundice, and liver failure in an 18-year-old male. Clin Pediatr (Phila). 2012 Jul; 51(7):699-702. PMID: 22399569.
    Citations:    Fields:    Translation:HumansCells
  26. Larson AM, Hedgire SS, Deshpande V, Stemmer-Rachamimov AO, Harisinghani MG, Ferrone CR, Shah U, Thiele EA. Pancreatic neuroendocrine tumors in patients with tuberous sclerosis complex. Clin Genet. 2012 Dec; 82(6):558-63. PMID: 22035404.
    Citations: 7     Fields:    Translation:Humans
  27. Shah U, Shenoy-Bhangle AS. Case records of the Massachusetts General Hospital. Case 32-2011. A 19-year-old man with recurrent pancreatitis. N Engl J Med. 2011 Oct 20; 365(16):1528-36. PMID: 22010920.
    Citations:    Fields:    Translation:Humans
  28. Mohan N, González-Peralta RP, Fujisawa T, Chang MH, Heller S, Jara P, Kelly D, Mieli-Vergani G, Shah U, Murray KF. Chronic hepatitis C virus infection in children. J Pediatr Gastroenterol Nutr. 2010 Feb; 50(2):123-31. PMID: 20038846.
    Citations: 14     Fields:    Translation:HumansCells
  29. Mieli-Vergani G, Heller S, Jara P, Vergani D, Chang MH, Fujisawa T, González-Peralta RP, Kelly D, Mohan N, Shah U, Murray KF. Autoimmune hepatitis. J Pediatr Gastroenterol Nutr. 2009 Aug; 49(2):158-64. PMID: 19561543.
    Citations: 23     Fields:    Translation:Humans
  30. Shah U, Frossard P, Moatter T. Cystic fibrosis: defining a disease under-diagnosed in Pakistan. Trop Med Int Health. 2009 May; 14(5):542-5. PMID: 19645745.
    Citations: 8     Fields:    Translation:Humans
  31. Shah U, Kelly D, Chang MH, Fujisawa T, Heller S, González-Peralta RP, Jara P, Mieli-Vergani G, Mohan N, Murray KF. Management of chronic hepatitis B in children. J Pediatr Gastroenterol Nutr. 2009 Apr; 48(4):399-404. PMID: 19322053.
    Citations: 13     Fields:    Translation:HumansCells
  32. Murray KF, Shah U, Mohan N, Heller S, González-Peralta RP, Kelly D, Chang MH, Mieli-Vergani G, Jara P, Fujisawa T. Chronic hepatitis. J Pediatr Gastroenterol Nutr. 2008 Aug; 47(2):225-33. PMID: 18664880.
    Citations:    Fields:    Translation:Humans
  33. Mirza R, Memon I, Cheema HA, Ali S, Thobani S, Shah U. Recommendations for the treatment of chronic hepatitis C infection in children. J Pak Med Assoc. 2007 Aug; 57(8):419-20. PMID: 17902528.
    Citations: 1     Fields:    Translation:Humans
  34. Shah U, Nadeem N, Husen Y, Fadoo Z. Imiglucerase treatment in Gaucher's disease. J Ayub Med Coll Abbottabad. 2007 Apr-Jun; 19(2):56-9. PMID: 18183722.
    Citations:    Fields:    Translation:Humans
  35. Shah U, Memon I, Cheema HA, Ali S, Thobani S, Mirza R. Recommendations for the treatment of chronic hepatitis B infection in children. J Pak Med Assoc. 2007 Apr; 57(4):204-7. PMID: 17489531.
    Citations:    Fields:    Translation:Humans
  36. Shah U, Shafiq Y, Khan MA. Gastrograffin use in distal intestinal obstruction syndrome of cystic fibrosis. J Ayub Med Coll Abbottabad. 2007 Jan-Mar; 19(1):58-60. PMID: 17867484.
    Citations:    Fields:    Translation:Humans
  37. Onyango AW, de Onis M, Caroli M, Shah U, Sguassero Y, Redondo N, Carroli B. Field-testing the WHO child growth standards in four countries. J Nutr. 2007 Jan; 137(1):149-52. PMID: 17182817.
    Citations: 10     Fields:    Translation:Humans
  38. Shah U, Moatter T, Bhutta ZA. Profile and factors determining outcome in a cohort of cystic fibrosis patients seen at the Aga Khan University Hospital, Karachi, Pakistan. J Trop Pediatr. 2006 Apr; 52(2):132-5. PMID: 16582405.
    Citations: 3     Fields:    Translation:Humans
  39. Shah U, Moatter T. Screening for cystic fibrosis: the importance of using the correct tools. J Ayub Med Coll Abbottabad. 2006 Jan-Mar; 18(1):7-10. PMID: 16773960.
    Citations:    Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  40. Shah U, Dickinson BL, Blumberg RS, Simister NE, Lencer WI, Walker WA. Distribution of the IgG Fc receptor, FcRn, in the human fetal intestine. Pediatr Res. 2003 Feb; 53(2):295-301. PMID: 12538789.
    Citations: 33     Fields:    Translation:HumansCells
  41. Shah U, Walker WA. Pathophysiology of intestinal food allergy. Adv Pediatr. 2002; 49:299-316. PMID: 12214776.
    Citations: 3     Fields:    Translation:HumansCells
  42. Bhutta ZA, Moattar T, Shah U. Genetic analysis of cystic fibrosis in Pakistan: a preliminary report. J Pak Med Assoc. 2000 Jul; 50(7):217-9. PMID: 10992696.
    Citations: 3     Fields:    Translation:Humans
  43. Shah U, Walker WA. Adverse host responses to bacterial toxins in human infants. J Nutr. 2000 02; 130(2S Suppl):420S-425S. PMID: 10721919.
    Citations:    Fields:    Translation:HumansAnimalsCells
  44. Shah U, Habib Z, Kleinman RE. Liver failure attributable to hepatitis A virus infection in a developing country. Pediatrics. 2000 Feb; 105(2):436-8. PMID: 10654972.
    Citations: 5     Fields:    Translation:Humans
  45. Shah U, Arshad M, Mozaffar T. Dysphagia in hereditary sensory autonomic neuropathy type IV. J Pak Med Assoc. 1999 May; 49(5):121-3. PMID: 10555429.
    Citations:    Fields:    Translation:Humans
  46. Shah U, Lavine JE, Buonomo C. Radiological case of the month. Redundant duodenal folds in cystic fibrosis. Arch Pediatr Adolesc Med. 1997 Mar; 151(3):311-2. PMID: 9080942.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.