Harvard Catalyst Profiles

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Vanessa Beynon, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Glenthøj A, van Beers EJ, Al-Samkari H, Viprakasit V, Kuo KHM, Galactéros F, Chonat S, Porter J, Zagadailov E, Xu R, Oluyadi A, Hawkins P, Gheuens S, Beynon V, Barcellini W. Mitapivat in adult patients with pyruvate kinase deficiency receiving regular transfusions (ACTIVATE-T): a multicentre, open-label, single-arm, phase 3 trial. Lancet Haematol. 2022 Oct; 9(10):e724-e732. PMID: 35988546.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  2. Al-Samkari H, Beynon V, van Beers EJ. Mitapivat versus Placebo for Pyruvate Kinase Deficiency. Reply. N Engl J Med. 2022 06 30; 386(26):2539. PMID: 35767454.
    Citations:    Fields:    Translation:Humans
  3. Beynon V, George IC, Elliott C, Arnold DL, Ke J, Chen H, Zhu L, Ke C, Giovannoni G, Scaramozza M, Campbell N, Bradley DP, Franchimont N, Gafson A, Belachew S. Chronic lesion activity and disability progression in secondary progressive multiple sclerosis. BMJ Neurol Open. 2022; 4(1):e000240. PMID: 35720980; PMCID: PMC9185385.
    Citations:    
  4. Fujiwara M, Raheja R, Garo LP, Ajay AK, Kadowaki-Saga R, Karandikar SH, Gabriely G, Krishnan R, Beynon V, Paul A, Patel A, Saxena S, Hu D, Healy BC, Chitnis T, Gandhi R, Weiner HL, Murugaiyan G. microRNA-92a promotes CNS autoimmunity by modulating the regulatory and inflammatory T cell balance. J Clin Invest. 2022 05 16; 132(10). PMID: 35298438; PMCID: PMC9106347.
    Citations:    Fields:    Translation:HumansAnimalsCells
  5. Al-Samkari H, Galactéros F, Glenthøj A, Rothman JA, Andres O, Grace RF, Morado-Arias M, Layton DM, Onodera K, Verhovsek M, Barcellini W, Chonat S, Judge MP, Zagadailov E, Xu R, Hawkins P, Beynon V, Gheuens S, van Beers EJ. Mitapivat versus Placebo for Pyruvate Kinase Deficiency. N Engl J Med. 2022 04 14; 386(15):1432-1442. PMID: 35417638.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  6. Alroughani R, Huppke P, Mazurkiewicz-Beldzinska M, Blaschek A, Valis M, Aaen G, Pultz J, Peng X, Beynon V. Delayed-Release Dimethyl Fumarate Safety and Efficacy in Pediatric Patients With Relapsing-Remitting Multiple Sclerosis. Front Neurol. 2020; 11:606418. PMID: 33473248.
    Citations: 3     
  7. Elliott C, Arnold DL, Chen H, Ke C, Zhu L, Chang I, Cahir-McFarland E, Fisher E, Zhu B, Gheuens S, Scaramozza M, Beynon V, Franchimont N, Bradley DP, Belachew S. Patterning Chronic Active Demyelination in Slowly Expanding/Evolving White Matter MS Lesions. AJNR Am J Neuroradiol. 2020 09; 41(9):1584-1591. PMID: 32819894.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  8. Garo LP, Ajay AK, Fujiwara M, Beynon V, Kuhn C, Gabriely G, Sadhukan S, Raheja R, Rubino S, Weiner HL, Murugaiyan G. Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity. Cell Rep. 2019 09 24; 28(13):3353-3366.e5. PMID: 31553906; PMCID: PMC6925592.
    Citations: 12     Fields:    Translation:HumansCells
  9. Raheja R, Regev K, Healy BC, Mazzola MA, Beynon V, Von Glehn F, Paul A, Diaz-Cruz C, Gholipour T, Glanz BI, Kivisakk P, Chitnis T, Weiner HL, Berry JD, Gandhi R. Correlating serum micrornas and clinical parameters in amyotrophic lateral sclerosis. Muscle Nerve. 2018 Aug; 58(2):261-269. PMID: 29466830.
    Citations: 39     Fields:    Translation:Humans
  10. Mazzola MA, Raheja R, Regev K, Beynon V, von Glehn F, Paul A, Pierre I, Kivisakk P, Weiner HL, Gandhi R. Monomethyl fumarate treatment impairs maturation of human myeloid dendritic cells and their ability to activate T cells. Mult Scler. 2019 01; 25(1):63-71. PMID: 29106333.
    Citations: 9     Fields:    Translation:HumansCells
  11. Garo LP, Beynon V, Murugaiyan G. Flow Cytometric Assessment of STAT Molecules in Th9 Cells. Methods Mol Biol. 2017; 1585:127-140. PMID: 28477192.
    Citations:    Fields:    Translation:Cells
  12. Mayo L, Cunha AP, Madi A, Beynon V, Yang Z, Alvarez JI, Prat A, Sobel RA, Kobzik L, Lassmann H, Quintana FJ, Weiner HL. IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammation. Brain. 2016 07; 139(Pt 7):1939-57. PMID: 27246324; PMCID: PMC4939696.
    Citations: 45     Fields:    Translation:AnimalsCells
  13. Murugaiyan G, Beynon V, Pires Da Cunha A, Joller N, Weiner HL. IFN-? limits Th9-mediated autoimmune inflammation through dendritic cell modulation of IL-27. J Immunol. 2012 Dec 01; 189(11):5277-83. PMID: 23125412; PMCID: PMC3504131.
    Citations: 34     Fields:    Translation:AnimalsCells
  14. Beynon V, Quintana FJ, Weiner HL. Activated human CD4+CD45RO+ memory T-cells indirectly inhibit NLRP3 inflammasome activation through downregulation of P2X7R signalling. PLoS One. 2012; 7(6):e39576. PMID: 22768094.
    Citations: 14     Fields:    Translation:HumansCells
  15. Mittal A, Murugaiyan G, Beynon V, Hu D, Weiner HL. IL-27 induction of IL-21 from human CD8+ T cells induces granzyme B in an autocrine manner. Immunol Cell Biol. 2012 Sep; 90(8):831-5. PMID: 22430249.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  16. Laroni A, Gandhi R, Beynon V, Weiner HL. IL-27 imparts immunoregulatory function to human NK cell subsets. PLoS One. 2011; 6(10):e26173. PMID: 22039443.
    Citations: 25     Fields:    Translation:HumansCells
  17. Murugaiyan G, Beynon V, Mittal A, Joller N, Weiner HL. Silencing microRNA-155 ameliorates experimental autoimmune encephalomyelitis. J Immunol. 2011 Sep 01; 187(5):2213-21. PMID: 21788439; PMCID: PMC3167080.
    Citations: 150     Fields:    Translation:AnimalsCells
  18. Beynon V, Cotofana S, Brand S, Lohse P, Mair A, Wagner S, Mussack T, Ochsenkühn T, Folwaczny M, Folwaczny C, Glas J, Török HP. NOD2/CARD15 genotype influences MDP-induced cytokine release and basal IL-12p40 levels in primary isolated peripheral blood monocytes. Inflamm Bowel Dis. 2008 Aug; 14(8):1033-40. PMID: 18383179.
    Citations: 21     Fields:    Translation:HumansCells
  19. Glas J, Beynon V, Bachstein B, Steckenbiller J, Manolis V, Euba A, Müller-Myhsok B, Folwaczny M. Increased plasma concentration of surfactant protein D in chronic periodontitis independent of SFTPD genotype: potential role as a biomarker. Tissue Antigens. 2008 Jul; 72(1):21-8. PMID: 18498293.
    Citations: 5     Fields:    Translation:HumansCells
  20. Glas J, Török HP, Tonenchi L, Wetzke M, Beynon V, Teshome MY, Cotofana S, Schiemann U, Griga T, Klein W, Epplen JT, Folwaczny C, Folwaczny M, Mussack T, Weiss EH. The 14-bp deletion polymorphism in the HLA-G gene displays significant differences between ulcerative colitis and Crohn's disease and is associated with ileocecal resection in Crohn's disease. Int Immunol. 2007 May; 19(5):621-6. PMID: 17446213.
    Citations: 8     Fields:    Translation:Humans
  21. Török HP, Glas J, Beynon V, Folwaczny M, Folwaczny C. Persistent dyspeptic symptoms in long-standing ulcerative colitis. Inflamm Bowel Dis. 2005 Oct; 11(10):951-2. PMID: 16189428.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.