Harvard Catalyst Profiles

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Wonhye Lee, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Wonhye Lee, Daniel S Weisholtz, Gary E Strangman, Seung-Schik Yoo. Safety review and perspectives of transcranial focused ultrasound brain stimulation. Brain Neurorehabil. 2021; 14(1):e4. View Publication.
  2. Jeong H, Im JJ, Park JS, Na SH, Lee W, Yoo SS, Song IU, Chung YA. A pilot clinical study of low-intensity transcranial focused ultrasound in Alzheimer's disease. Ultrasonography. 2021 Oct; 40(4):512-519. PMID: 33730775.
    Citations: 4     
  3. Xu L, Lee W, Rotenberg A, Böhlke M, Yoon K, Yoo SS. Localized Disruption of Blood Albumin-Phenytoin Binding Using Transcranial Focused Ultrasound. Ultrasound Med Biol. 2020 08; 46(8):1986-1997. PMID: 32402673.
    Citations: 2     Fields:    Translation:AnimalsCells
  4. Cammalleri A, Croce P, Lee W, Yoon K, Yoo SS. Therapeutic Potentials of Localized Blood-Brain Barrier Disruption by Noninvasive Transcranial Focused Ultrasound: A Technical Review. J Clin Neurophysiol. 2020 Mar; 37(2):104-117. PMID: 32142021.
    Citations: 4     Fields:    Translation:HumansAnimals
  5. Yoon K, Lee W, Lee JE, Xu L, Croce P, Foley L, Yoo SS. Effects of sonication parameters on transcranial focused ultrasound brain stimulation in an ovine model. PLoS One. 2019; 14(10):e0224311. PMID: 31648261.
    Citations: 18     Fields:    Translation:Animals
  6. Yoon K, Lee W, Chen E, Lee JE, Croce P, Cammalleri A, Foley L, Tsao AL, Yoo SS. Localized Blood-Brain Barrier Opening in Ovine Model Using Image-Guided Transcranial Focused Ultrasound. Ultrasound Med Biol. 2019 09; 45(9):2391-2404. PMID: 31217090.
    Citations: 5     Fields:    Translation:Animals
  7. Lee W, Croce P, Margolin RW, Cammalleri A, Yoon K, Yoo SS. Transcranial focused ultrasound stimulation of motor cortical areas in freely-moving awake rats. BMC Neurosci. 2018 Sep 19; 19(1):57. PMID: 30231861.
    Citations: 20     Fields:    Translation:Animals
  8. Yoon K, Lee W, Croce P, Cammalleri A, Yoo SS. Multi-resolution simulation of focused ultrasound propagation through ovine skull from a single-element transducer. Phys Med Biol. 2018 05 10; 63(10):105001. PMID: 29658494.
    Citations: 9     Fields:    Translation:Animals
  9. Yoo SS, Yoon K, Croce P, Cammalleri A, Margolin RW, Lee W. Focused ultrasound brain stimulation to anesthetized rats induces long-term changes in somatosensory evoked potentials. Int J Imaging Syst Technol. 2018; 28(2):106-112. View Publication.
  10. Min D, Lee W, Bae IH, Lee TR, Croce P, Yoo SS. Bioprinting of biomimetic skin containing melanocytes. Exp Dermatol. 2018 05; 27(5):453-459. PMID: 28453913.
    Citations: 27     Fields:    Translation:HumansCells
  11. Yoo SS, Lee W, Jolesz FA. FUS-mediated image-guided neuromodulation of the brain. In: Neurophotonics and Brain Mapping. Chen Y, Kateb B, editors. 2017; 443-455. View Publication.
  12. Lee W, Kim S, Kim B, Lee C, Chung YA, Kim L, Yoo SS. Non-invasive transmission of sensorimotor information in humans using an EEG/focused ultrasound brain-to-brain interface. PLoS One. 2017; 12(6):e0178476. PMID: 28598972.
    Citations: 11     Fields:    Translation:HumansCells
  13. Yoo SH, Croce P, Margolin RW, Lee SD, Lee W. Pulsed focused ultrasound changes nerve conduction of earthworm giant axonal fibers. Neuroreport. 2017 Mar 01; 28(4):229-233. PMID: 28145994.
    Citations: 4     Fields:    Translation:AnimalsCells
  14. Lee W, Chung YA, Jung Y, Song IU, Yoo SS. Simultaneous acoustic stimulation of human primary and secondary somatosensory cortices using transcranial focused ultrasound. BMC Neurosci. 2016 10 26; 17(1):68. PMID: 27784293.
    Citations: 40     Fields:    Translation:Humans
  15. Lee W, Kim HC, Jung Y, Chung YA, Song IU, Lee JH, Yoo SS. Transcranial focused ultrasound stimulation of human primary visual cortex. Sci Rep. 2016 Sep 23; 6:34026. PMID: 27658372.
    Citations: 78     Fields:    
  16. Lee SD, Jung Y, Chung YA, Lee W. Neural substrates in secondary somatosensory area for the perception of different tactile sensations. Int J Imaging Syst Technol. 2016; 26(1):85-91. View Publication.
  17. Lee W, Lee SD, Park MY, Foley L, Purcell-Estabrook E, Kim H, Fischer K, Maeng LS, Yoo SS. Image-Guided Focused Ultrasound-Mediated Regional Brain Stimulation in Sheep. Ultrasound Med Biol. 2016 Feb; 42(2):459-70. PMID: 26525652.
    Citations: 51     Fields:    Translation:Animals
  18. Lee W, Lee SD, Park MY, Foley L, Purcell-Estabrook E, Kim H, Yoo SS. Functional and diffusion tensor magnetic resonance imaging of the sheep brain. BMC Vet Res. 2015 Oct 14; 11:262. PMID: 26467856.
    Citations: 7     Fields:    Translation:Animals
  19. W Lee, H Kim, SD Lee, MY Park, SS Yoo. FUS-mediated functional neuromodulation for neurophysiologic assessment in a large animal model. J Ther Ultrasound. 2015; 3(Suppl 1):O23. View Publication.
  20. Lee W, Kim H, Jung Y, Song IU, Chung YA, Yoo SS. Image-guided transcranial focused ultrasound stimulates human primary somatosensory cortex. Sci Rep. 2015 Mar 04; 5:8743. PMID: 25735418.
    Citations: 97     Fields:    Translation:Humans
  21. Kim H, Park MY, Lee SD, Lee W, Chiu A, Yoo SS. Suppression of EEG visual-evoked potentials in rats through neuromodulatory focused ultrasound. Neuroreport. 2015 Mar 04; 26(4):211-5. PMID: 25646585.
    Citations: 31     Fields:    Translation:Animals
  22. Lee W, Lee SD, Park MY, Yang J, Yoo SS. Evaluation of polyvinyl alcohol cryogel as an acoustic coupling medium for low-intensity transcranial focused ultrasound. Int J Imaging Syst Technol. 2014; 24(4):332-338. View Publication.
  23. Yoo SS, Rama S, Szewczyk B, Pui JWY, Lee W, Kim L. Endoscopic capsule robots using reconfigurable modular assembly: A pilot study. Int J Imaging Syst Technol. 2014; 24(4):359-365. View Publication.
  24. Yoo SS, Lee W, Kim H. Pulsed application of focused ultrasound to the LI4 elicits deqi sensations: pilot study. Complement Ther Med. 2014 Aug; 22(4):592-600. PMID: 25146060.
    Citations: 5     Fields:    Translation:Humans
  25. Lee W, Kim H, Lee S, Yoo SS, Chung YA. . Creation of various skin sensations using pulsed focused ultrasound: evidence for functional neuromodulation. Int J Imaging Syst Technol. 2014; 24(2):167-174. View Publication.
  26. Lee W, Bae CY, Kwon S, Son J, Kim J, Jeong Y, Yoo SS, Park JK. Cellular hydrogel biopaper for patterned 3D cell culture and modular tissue reconstruction. Adv Healthc Mater. 2012 Sep; 1(5):635-9. PMID: 23184799.
    Citations: 3     Fields:    Translation:HumansCells
  27. Yang PS, Kim H, Lee W, Bohlke M, Park S, Maher TJ, Yoo SS. Transcranial focused ultrasound to the thalamus is associated with reduced extracellular GABA levels in rats. Neuropsychobiology. 2012; 65(3):153-60. PMID: 22378299.
    Citations: 26     Fields:    Translation:AnimalsCells
  28. Lee DH, Lee W, Um E, Park JK. Microbridge structures for uniform interval control of flowing droplets in microfluidic networks. Biomicrofluidics. 2011 Sep; 5(3):34117-341179. PMID: 22662043.
    Citations: 2     
  29. Lee W, Son J, Yoo SS, Park JK. Facile and biocompatible fabrication of chemically sol-gel transitional hydrogel free-standing microarchitectures. Biomacromolecules. 2011 Jan 10; 12(1):14-8. PMID: 21138286.
    Citations: 3     Fields:    Translation:HumansCells
  30. Sohn H, Kim I, Lee W, Peterson BS, Hong H, Chae JH, Hong S, Jeong J. Linear and non-linear EEG analysis of adolescents with attention-deficit/hyperactivity disorder during a cognitive task. Clin Neurophysiol. 2010 Nov; 121(11):1863-70. PMID: 20659814.
    Citations: 17     Fields:    Translation:Humans
  31. Lee W, Lee V, Polio S, Keegan P, Lee JH, Fischer K, Park JK, Yoo SS. On-demand three-dimensional freeform fabrication of multi-layered hydrogel scaffold with fluidic channels. Biotechnol Bioeng. 2010 Apr 15; 105(6):1178-86. PMID: 19953677.
    Citations: 53     Fields:    Translation:Cells
  32. Lee YB, Polio S, Lee W, Dai G, Menon L, Carroll RS, Yoo SS. Bio-printing of collagen and VEGF-releasing fibrin gel scaffolds for neural stem cell culture. Exp Neurol. 2010 Jun; 223(2):645-52. PMID: 20211178.
    Citations: 69     Fields:    Translation:AnimalsCells
  33. Yoo SS, Lee W, Park JK. On-demand 3D freeform fabrication of tissue structures using bioprinting. In: Methods in Bioengineering: 3D Tissue Engineering. Yarmush ML, Langer RS, editors. 2010; 167-185.
  34. Lee W, Pinckney J, Lee V, Lee JH, Fischer K, Polio S, Park JK, Yoo SS. Three-dimensional bioprinting of rat embryonic neural cells. Neuroreport. 2009 May 27; 20(8):798-803. PMID: 19369905.
    Citations: 28     Fields:    Translation:AnimalsCells
  35. Kim MS, Lee W, Park JK. Nanobiotechnology for stem cell culture and maintenance. In: Emerging Technology Platforms for Stem Cells. Lakshmipathy U, Chesnut JD, Thyagarajan B, editors. 2009; 291-310.
  36. Lee W, Debasitis JC, Lee VK, Lee JH, Fischer K, Edminster K, Park JK, Yoo SS. Multi-layered culture of human skin fibroblasts and keratinocytes through three-dimensional freeform fabrication. Biomaterials. 2009 Mar; 30(8):1587-95. PMID: 19108884.
    Citations: 97     Fields:    Translation:HumansCells
  37. Kim MS, Lee W, Kim YC, Park JK. Microvalve-assisted patterning platform for measuring cellular dynamics based on 3D cell culture. Biotechnol Bioeng. 2008 Dec 01; 101(5):1005-13. PMID: 18942775.
    Citations: 4     Fields:    Translation:HumansCells
  38. Kang JH, Choi S, Lee W, Park JK. Isomagnetophoresis to discriminate subtle difference in magnetic susceptibility. J Am Chem Soc. 2008 Jan 16; 130(2):396-7. PMID: 18081285.
    Citations: 7     Fields:    
  39. Lee J, Kim H, Lee W, Chung D, Bhak J. BioSubroutine: an open web server for bioinformatics algorithms and subroutines. Genomics Inform. 2005; 3(1):35-38. View Publication.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.