Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Barbara Emily Bierer, M.D.



Determining the Optimal Pathway for Clinical Trial Management at Montefiore/Einstein
Summer, 06/13/13 - 08/08/13

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R13FD007293 (BIERER, BARBARA E) Jan 15, 2021 - Dec 31, 2023
    Global Cooperation to Promote Clinical Research in Children
    Role: Principal Investigator
  2. R13FD006905 (BIERER, BARBARA E) Feb 1, 2020 - Jan 31, 2021
    Innovative statistical methodologies to subgroup analysis in clinical trials
    Role: Principal Investigator
  3. R25HL115510 (LEWIS, ELDRIN F) Aug 1, 2012 - Feb 28, 2018
    Short-Term Research Education Program to Increase Diversity in Health-Related Res
    Role: Principal Investigator
  4. R25HL096364 (BIERER, BARBARA E) Apr 1, 2009 - Mar 31, 2015
    Short-Term Training in Cardiovascular Research
    Role: Principal Investigator
  5. N01HB067133 (GUINAN, EVA C) Sep 30, 1996 - Sep 30, 2001
    Centers For Clinical Research on TransplantaTION
    Role: Co-Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Sonstein SA, Samuels E, Aldinger C, White SA, Bierer BE. Self-assessed Competencies of Clinical Research Professionals and Recommendations for Further Education and Training. Ther Innov Regul Sci. 2022 Mar 31. PMID: 35357687.
    Citations:    Fields:    
  2. Stefano LD, Ogburn EL, Ram M, Scharfstein DO, Li T, Khanal P, Baksh SN, McBee N, Gruber J, Gildea MR, Goldenberg NA, Bennani Y, Brown SM, Buckel WR, Clement ME, Mulligan MJ, Oâ Halloran JA, Rauseo AM, Self WH, Semler MW, Seto T, Stout JE, Ulrich RJ, Victory J, Bierer BE, Hanley DF, Freilich D. Hydroxychloroquine/Chloroquine for the Treatment of Hospitalized Patients with COVID-19: An Individual Participant Data Meta-Analysis. medRxiv. 2022 Jan 11. PMID: 35043124.
  3. Sonstein SA, Kim LP, Ichhpurani N, Padbidri R, White SA, Aldinger CE, Bierer BE. Incorporating Competencies Related to Project Management into the Joint Taskforce Core Competency Framework for Clinical Research Professionals. Ther Innov Regul Sci. 2022 03; 56(2):206-211. PMID: 34988928.
    Citations:    Fields:    
  4. Liss J, Peloquin D, Barnes M, Bierer BE. Applying Civil Rights Law to Clinical Research: Title VI's Equal Access Mandate. J Law Med Ethics. 2022; 50(1):101-108. PMID: 35243995.
    Citations:    Fields:    
  5. Spector-Bagdady K, Lynch HF, Bierer BE, Gelinas L, Hull SC, Magnus D, Meyer MN, Sharp RR, Sugarman J, Wilfond BS, Yearby R, Mohapatra S. Allocation of Opportunities to Participate in Clinical Trials during the Covid-19 Pandemic and Other Public Health Emergencies. Hastings Cent Rep. 2022 01; 52(1):51-58. PMID: 34908169.
    Citations:    Fields:    Translation:HumansPHPublic Health
  6. Bierer BE, Ne'eman A, DeCormier Plosky W, Strauss DH, Silverman BC, Stein MA. Integrating Supported Decision-Making into the Clinical Research Process. Am J Bioeth. 2021 11; 21(11):32-35. PMID: 34710013.
    Citations: 1     Fields:    Translation:Humans
  7. Tse T, White S, Gelinas L, Morrell W, Bierer B, Zarin DA. Characterization of Informed Consent Forms Posted on ClinicalTrials.gov. JAMA Netw Open. 2021 11 01; 4(11):e2135146. PMID: 34792593.
    Citations: 1     Fields:    Translation:Humans
  8. Liss J, Peloquin D, Barnes M, Bierer BE. Demystifying Schrems II for the cross-border transfer of clinical research data. J Law Biosci. 2021 Jul-Dec; 8(2):lsab032. PMID: 34703612.
  9. Seykora A, Coleman C, Rosenfeld SJ, Bierer BE, Lynch HF. Steps toward a System of IRB Precedent: Piloting Approaches to Summarizing IRB Decisions for Future Use. Ethics Hum Res. 2021 Nov; 43(6):2-18. PMID: 34676693.
    Citations:    Fields:    Translation:Humans
  10. South A, Joharatnam-Hogan N, Purvis C, James EC, Diaz-Montana C, Cragg WJ, Tweed C, Macnair A, Sydes MR, Snowdon C, Gillies K, Isaacs T, Bierer BE, Copas AJ. Testing approaches to sharing trial results with participants: The Show RESPECT cluster randomised, factorial, mixed methods trial. PLoS Med. 2021 10; 18(10):e1003798. PMID: 34606495.
    Citations:    Fields:    Translation:Humans
  11. Muthukumar AV, Morrell W, Bierer BE. Evaluating the frequency of English language requirements in clinical trial eligibility criteria: A systematic analysis using ClinicalTrials.gov. PLoS Med. 2021 09; 18(9):e1003758. PMID: 34520467.
    Citations:    Fields:    Translation:Humans
  12. Bierer BE, White SA, Gelinas L, Strauss DH. Fair payment and just benefits to enhance diversity in clinical research. J Clin Transl Sci. 2021; 5(1):e159. PMID: 34527298.
  13. Gelinas L, Morrell W, White SA, Bierer BE. Navigating the ethics of remote research data collection. Clin Trials. 2021 10; 18(5):606-614. PMID: 34231414.
    Citations: 1     Fields:    Translation:Humans
  14. Gelinas L, Morrell W, White SA, Bierer BE. Online Research Participant Communication: Balancing Benefits and Risks. Ethics Hum Res. 2021 Jul; 43(4):2-10. PMID: 34196504.
    Citations:    Fields:    Translation:Humans
  15. Strauss DH, White SA, Bierer BE. Justice, diversity, and research ethics review. Science. 2021 Mar 19; 371(6535):1209-1211. PMID: 33737478.
    Citations:    Fields:    
  16. Kasozi KI, Laudisoit A, Osuwat LO, Batiha GE, Al Omairi NE, Aigbogun E, Ninsiima HI, Usman IM, DeTora LM, MacLeod ET, Nalugo H, Crawley FP, Bierer BE, Mwandah DC, Kato CD, Kiyimba K, Ayikobua ET, Lillian L, Matama K, Nelly Mak SC, Onanyang D, Pius T, Nalumenya DP, Ssebuufu R, Rugambwa NO, Musoke GH, Bardosh K, Ochieng JJ, Ssempijja F, Kyamanywa P, Tumwine G, Alzahrani KJ, Welburn SC. A Descriptive-Multivariate Analysis of Community Knowledge, Confidence, and Trust in COVID-19 Clinical Trials among Healthcare Workers in Uganda. Vaccines (Basel). 2021 Mar 12; 9(3). PMID: 33809269.
    Citations: 5     
  17. Shamsoddin E, DeTora LM, Tovani-Palone MR, Bierer BE. Dental Care in Times of the COVID-19 Pandemic: A Review. Med Sci (Basel). 2021 02 19; 9(1). PMID: 33669898.
    Citations: 7     Fields:    Translation:HumansPHPublic Health
  18. Meyer MN, Gelinas L, Bierer BE, Hull SC, Joffe S, Magnus D, Mohapatra S, Sharp RR, Spector-Bagdady K, Sugarman J, Wilfond BS, Lynch HF. An ethics framework for consolidating and prioritizing COVID-19 clinical trials. Clin Trials. 2021 04; 18(2):226-233. PMID: 33530721.
    Citations: 6     Fields:    Translation:HumansCells
  19. Bovenberg J, Peloquin D, Bierer B, Barnes M, Knoppers BM. Raising standards for global data-sharing-Response. Science. 2021 01 08; 371(6525):134-135. PMID: 33414214.
    Citations:    Fields:    
  20. Crown WH, Bierer BE. Real-World Evidence: Understanding Sources of Variability Through Empirical Analysis. Value Health. 2021 01; 24(1):116-117. PMID: 33431144.
    Citations: 1     Fields:    
  21. Bierer BE, White SA, Barnes JM, Gelinas L. Ethical Challenges in Clinical Research During the COVID-19 Pandemic. J Bioeth Inq. 2020 Dec; 17(4):717-722. PMID: 33169251.
    Citations: 7     Fields:    Translation:HumansCellsPHPublic Health
  22. Bovenberg J, Peloquin D, Bierer B, Barnes M, Knoppers BM. How to fix the GDPR's frustration of global biomedical research. Science. 2020 10 02; 370(6512):40-42. PMID: 33004505.
    Citations: 9     Fields:    Translation:HumansPHPublic Health
  23. Asch DA, Joffe S, Bierer BE, Greene SM, Lieu TA, Platt JE, Whicher D, Ahmed M, Platt R. Rethinking ethical oversight in the era of the learning health system. Healthc (Amst). 2020 Dec; 8(4):100462. PMID: 32992106.
    Citations: 1     Fields:    Translation:Humans
  24. Ogburn EL, Bierer BE, Brookmeyer R, Choirat C, Dean NE, De Gruttola V, Ellenberg SS, Halloran ME, Hanley DF, Lee JK, Wang R, Scharfstein DO. Aggregating data from COVID-19 trials. Science. 2020 06 12; 368(6496):1198-1199. PMID: 32527823.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  25. Sim I, Stebbins M, Bierer BE, Butte AJ, Drazen J, Dzau V, Hernandez AF, Krumholz HM, Lo B, Munos B, Perakslis E, Rockhold F, Ross JS, Terry SF, Yamamoto KR, Zarin DA, Li R. Time for NIH to lead on data sharing. Science. 2020 03 20; 367(6484):1308-1309. PMID: 32193313.
    Citations: 10     Fields:    
  26. Peloquin D, DiMaio M, Bierer B, Barnes M. Disruptive and avoidable: GDPR challenges to secondary research uses of data. Eur J Hum Genet. 2020 06; 28(6):697-705. PMID: 32123329.
    Citations: 14     Fields:    Translation:Humans
  27. Holthaus K, Goldberg D, Connelly C, Corning B, Nascimento C, Witte E, Bierer BE. Facilitating collaborative animal research: The development and implementation of a Master Reciprocal Institutional Agreement for Animal Care and Use. J Clin Transl Sci. 2020 Apr; 4(2):96-101. PMID: 32313698.
    Citations: 1     
  28. Caruso R, Myatt T, Bierer BE. Innovation in biosafety oversight: The Harvard Catalyst Common Reciprocal IBC Reliance Authorization Agreement. J Clin Transl Sci. 2020 Apr; 4(2):90-95. PMID: 32313697.
  29. Statham EE, White SA, Sonwane B, Bierer BE. Primed to comply: Individual participant data sharing statements on ClinicalTrials.gov. PLoS One. 2020; 15(2):e0226143. PMID: 32069305.
    Citations: 3     Fields:    Translation:Humans
  30. Gelinas L, White SA, Bierer BE. Economic vulnerability and payment for research participation. Clin Trials. 2020 06; 17(3):264-272. PMID: 32063065.
    Citations: 5     Fields:    Translation:Humans
  31. Zarin DA, Crown WH, Bierer BE. Issues in the registration of database studies. J Clin Epidemiol. 2020 05; 121:29-31. PMID: 31972275.
    Citations:    Fields:    
  32. Sonstein SA, Namenek Brouwer RJ, Gluck W, Robert Kolb H, Aldinger C, Bierer BE, Thomas Jones C. Leveling the Joint Task Force Core Competencies for Clinical Research Professionals. Ther Innov Regul Sci. 2020 01; 54(1):1-20. PMID: 32008235.
    Citations: 5     Fields:    Translation:Humans
  33. Ahmed HR, Strauss DH, Bierer BE. Committing to the Inclusion of Diverse Populations in Clinical Research. Ther Innov Regul Sci. 2020 07; 54(4):922-924. PMID: 32557312.
    Citations:    Fields:    Translation:Humans
  34. Barnes M, Flaherty J, Bierer BE. Research Subject Injury Compensation: The Ongoing Search for Fairness, Consistency and Clarity. J Law Med Ethics. 2019 12; 47(4):748-750. PMID: 31957589.
    Citations:    Fields:    Translation:Humans
  35. Kassis SB, White SA, Myers L, Trudeau C, Bierer BE. Advancing Health Literacy in Clinical Research: Clear Communications for Every Participant. NAM Perspect. 2019; 2019. PMID: 34532669.
  36. Davis JM, Yao L, Bierer BE. Protecting Pregnant Women With Substance Use Disorders and Their Neonates Participating in Research. JAMA. 2019 Aug 20; 322(7):609-610. PMID: 31298683.
    Citations: 1     Fields:    
  37. Cobb N, Witte E, Cervone M, Kirby A, MacFadden D, Nadler L, Bierer BE. The SMART IRB platform: A national resource for IRB review for multisite studies. J Clin Transl Sci. 2019 Aug; 3(4):129-139. PMID: 31660237.
    Citations: 12     
  38. Gelinas L, Crawford B, Kelman A, Bierer BE. Relocation of study participants for rare and ultra-rare disease trials: Ethics and operations. Contemp Clin Trials. 2019 09; 84:105812. PMID: 31330189.
    Citations: 4     Fields:    Translation:Humans
  39. Gelinas L, Bierer BE. Social Media as an Ethical Tool for Retention in Clinical Trials. Am J Bioeth. 2019 06; 19(6):62-64. PMID: 31135316.
    Citations: 2     Fields:    Translation:Humans
  40. Pierce HH, Dev A, Statham E, Bierer BE. Credit data generators for data reuse. Nature. 2019 06; 570(7759):30-32. PMID: 31164773.
    Citations: 11     Fields:    Translation:PHPublic Health
  41. Bierer BE, Gelinas L. Scientific Merit Predicates Ethical Review of Clinical Research. Ethics Hum Res. 2019 05; 41(3):29-32. PMID: 31108574.
    Citations:    Fields:    
  42. Vardeny O, Hernandez AF, Cohen LW, Franklin A, Baqai M, Palmer S, Bierer BE, Cobb N. Transitioning to the National Institutes of Health single institutional review board model: Piloting the use of the Streamlined, Multi-site, Accelerated Resources for Trials IRB Reliance. Clin Trials. 2019 06; 16(3):290-296. PMID: 30866676.
    Citations: 4     Fields:    Translation:Humans
  43. Aldinger CE, Ligibel J, Shin IH, Denninger JW, Bierer BE. Returning aggregate results of clinical trials: Empirical data of patient preferences. J Clin Transl Sci. 2018 Dec; 2(6):356-362. PMID: 31404276.
    Citations: 2     
  44. Bierer BE, Strauss DH, White SA, Zarin DA. Universal Funder Responsibilities That Advance Social Value. Am J Bioeth. 2018 Nov; 18(11):30-32. PMID: 30475185.
    Citations: 2     Fields:    Translation:Humans
  45. Sonstein SA, Namenek Brower RJ, Gluck W, Kolb HR, Aldinger C, Bierer BE, Jones CT. Leveling the Joint Task Force Core Competencies for Clinical Research Professionals. Ther Innov Regul Sci. 2018 Oct 18; 2168479018799291. PMID: 30336683.
    Citations: 1     
  46. Balsari S, Fortenko A, Blaya JA, Gropper A, Jayaram M, Matthan R, Sahasranam R, Shankar M, Sarbadhikari SN, Bierer BE, Mandl KD, Mehendale S, Khanna T. Reimagining Health Data Exchange: An Application Programming Interface-Enabled Roadmap for India. J Med Internet Res. 2018 07 13; 20(7):e10725. PMID: 30006325.
    Citations: 8     Fields:    Translation:HumansPHPublic Health
  47. Witte E, Winkler SJ, Myerson J, Kirby A, Biggers J, Do JM, Roth MT, Gateman AK, Cagliero E, Bierer BE. Development of a plain-language library of educational resources for research participants. J Clin Transl Sci. 2018 Feb; 2(1):27-30. PMID: 31660216.
  48. Murray PD, Bierer BE, Hirschfeld S, Klein AK, Davis JM. Assessment of a shortened informed consent form for pediatric research: a pilot study. Pediatr Res. 2018 10; 84(4):516-519. PMID: 29967521.
    Citations: 2     Fields:    Translation:Humans
  49. Gelinas L, Lynch HF, Largent EA, Shachar C, Cohen IG, Bierer BE. Truth in Advertising: Disclosure of Participant Payment in Research Recruitment Materials. Ther Innov Regul Sci. 2018 05; 52(3):268-274. PMID: 29714586.
    Citations: 1     Fields:    Translation:Humans
  50. Gelinas L, Lynch HF, Bierer BE, Cohen IG. On Scarcity and the Value of Clinical Trials. Am J Bioeth. 2018 04; 18(4):71-73. PMID: 29621470.
    Citations:    Fields:    Translation:Humans
  51. Gelinas L, Largent EA, Cohen IG, Kornetsky S, Bierer BE, Fernandez Lynch H. A Framework for Ethical Payment to Research Participants. N Engl J Med. 2018 02 22; 378(8):766-771. PMID: 29466147.
    Citations: 32     Fields:    Translation:Humans
  52. Ohmann C, Banzi R, Canham S, Battaglia S, Matei M, Ariyo C, Becnel L, Bierer B, Bowers S, Clivio L, Dias M, Druml C, Faure H, Fenner M, Galvez J, Ghersi D, Gluud C, Groves T, Houston P, Karam G, Kalra D, Knowles RL, Krleža-Jeric K, Kubiak C, Kuchinke W, Kush R, Lukkarinen A, Marques PS, Newbigging A, O'Callaghan J, Ravaud P, Schlünder I, Shanahan D, Sitter H, Spalding D, Tudur-Smith C, van Reusel P, van Veen EB, Visser GR, Wilson J, Demotes-Mainard J. Sharing and reuse of individual participant data from clinical trials: principles and recommendations. BMJ Open. 2017 Dec 14; 7(12):e018647. PMID: 29247106.
    Citations: 48     Fields:    Translation:Humans
  53. Bierer BE. The Revised and Final Common Rule: An Unfinished Story. IRB. 2017 Nov-Dec; 39(6):6-10. PMID: 30707525.
    Citations:    Fields:    
  54. Nichols L, Brako L, Rivera SM, Tahmassian A, Jones MF, Pierce HH, Bierer BE. What do revised U.S. rules mean for human research? Science. 2017 Aug 18; 357(6352):650-651. PMID: 28818933.
    Citations:    Fields:    Translation:Humans
  55. Bierer BE, Strober W. Venipuncture Procedures: Sources of Human Peripheral Blood Cells, Serum, and Plasma. Curr Protoc Immunol. 2017 Aug 01; 118:A.3F.1-A.3F.5. PMID: 28762484.
    Citations:    Fields:    Translation:HumansCells
  56. Bierer BE. Universal Precautions: Necessary Safety Procedures When Handling Human Blood, Body Fluids, and Specimens. Curr Protoc Immunol. 2017 Aug 01; 118:A.3P.1-A.3P.3. PMID: 28762486.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  57. Bierer BE, Crosas M, Pierce HH. Data Authorship as an Incentive to Data Sharing. N Engl J Med. 2017 07 27; 377(4):402. PMID: 28745980.
    Citations: 4     Fields:    Translation:Humans
  58. Gelinas L, Pierce R, Winkler S, Cohen G, Lynch HF, Bierer BE. Nonexceptionalism, Research Risks, and Social Media: Response to Open Peer Commentaries on "Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations". Am J Bioeth. 2017 05; 17(5):W1-W3. PMID: 28430072.
    Citations: 2     Fields:    Translation:Humans
  59. Cancedda C, Riviello R, Wilson K, Scott KW, Tuteja M, Barrow JR, Hedt-Gauthier B, Bukhman G, Scott J, Milner D, Raviola G, Weissman B, Smith S, Nuthulaganti T, McClain CD, Bierer BE, Farmer PE, Becker AE, Binagwaho A, Rhatigan J, Golan DE. Building Workforce Capacity Abroad While Strengthening Global Health Programs at Home: Participation of Seven Harvard-Affiliated Institutions in a Health Professional Training Initiative in Rwanda. Acad Med. 2017 05; 92(5):649-658. PMID: 28328735.
    Citations: 4     Fields:    Translation:Humans
  60. Bierer BE, Barnes M, Lynch HF. Revised 'Common Rule' Shapes Protections For Research Participants. Health Aff (Millwood). 2017 05 01; 36(5):784-788. PMID: 28461343.
    Citations: 6     Fields:    Translation:Humans
  61. Gelinas L, Lynch HF, Bierer B, Cohen IG. Institutions as an ethical locus of research prioritisation. J Med Ethics. 2017 12; 43(12):816-818. PMID: 28385733.
    Citations:    Fields:    Translation:Humans
  62. Bierer BE, Crosas M, Pierce HH. Data Authorship as an Incentive to Data Sharing. N Engl J Med. 2017 04 27; 376(17):1684-1687. PMID: 28402238.
    Citations: 31     Fields:    
  63. Gelinas L, Pierce R, Winkler S, Cohen IG, Lynch HF, Bierer BE. Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations. Am J Bioeth. 2017 Mar; 17(3):3-14. PMID: 28207365.
    Citations: 73     Fields:    Translation:Humans
  64. Gelinas L, Lynch HF, Bierer BE, Cohen IG. When clinical trials compete: prioritising study recruitment. J Med Ethics. 2017 12; 43(12):803-809. PMID: 28108613.
    Citations: 12     Fields:    Translation:Humans
  65. Lynch HF, Cohen IG, Bierer BE. Public Engagement, Notice-and-Comment Rulemaking, and the Common Rule. IRB. 2017 Jan-Feb; 39(1):17-9. PMID: 30148327.
    Citations:    Fields:    
  66. Saks MJ, Albright T, Bohan TL, Bierer BE, Bowers CM, Bush MA, Bush PJ, Casadevall A, Cole SA, Denton MB, Diamond SS, Dioso-Villa R, Epstein J, Faigman D, Faigman L, Fienberg SE, Garrett BL, Giannelli PC, Greely HT, Imwinkelried E, Jamieson A, Kafadar K, Kassirer JP, Koehler J', Korn D, Mnookin J, Morrison AB, Murphy E, Peerwani N, Peterson JL, Risinger DM, Sensabaugh GF, Spiegelman C, Stern H, Thompson WC, Wayman JL, Zabell S, Zumwalt RE. Forensic bitemark identification: weak foundations, exaggerated claims. J Law Biosci. 2016 Dec; 3(3):538-575. PMID: 28852538.
    Citations: 5     
  67. Bierer BE, Li R, Seltzer J, Sleeper LA, Frank E, Knirsch C, Aldinger CE, Levine RJ, Massaro J, Shah A, Barnes M, Snapinn S, Wittes J. Responsibilities of Data Monitoring Committees: Consensus Recommendations. Ther Innov Regul Sci. 2016 Sep; 50(5):648-659. PMID: 30231760.
    Citations: 3     Fields:    
  68. Bierer BE, Li R, Barnes M, Sim I. A Global, Neutral Platform for Sharing Trial Data. N Engl J Med. 2016 Jun 23; 374(25):2411-3. PMID: 27168194.
    Citations: 40     Fields:    Translation:Humans
  69. Antman EM, Bierer BE. Standards for Clinical Research: Keeping Pace With the Technology of the Future. Circulation. 2016 Mar 01; 133(9):823-5. PMID: 26927004.
    Citations: 3     Fields:    Translation:Humans
  70. Li RH, Wacholtz MC, Barnes M, Boggs L, Callery-D'Amico S, Davis A, Digilova A, Forster D, Heffernan K, Luthin M, Lynch HF, McNair L, Miller JE, Murphy J, Van Campen L, Wilenzick M, Wolf D, Woolston C, Aldinger C, Bierer BE. Incorporating ethical principles into clinical research protocols: a tool for protocol writers and ethics committees. J Med Ethics. 2016 Apr; 42(4):229-34. PMID: 26811365.
    Citations: 3     Fields:    Translation:Humans
  71. Lynch HF, Bierer BE, Cohen IG. Confronting Biospecimen Exceptionalism in Proposed Revisions to the Common Rule. Hastings Cent Rep. 2016 Jan-Feb; 46(1):4-5. PMID: 26786034.
    Citations: 6     Fields:    Translation:Humans
  72. Borus JF, Alexander EK, Bierer BE, Bringhurst FR, Clark C, Klanica KE, Stewart EC, Friedman LS. The Education Review Board: A Mechanism for Managing Potential Conflicts of Interest in Medical Education. Acad Med. 2015 Dec; 90(12):1611-7. PMID: 26083402.
    Citations: 3     Fields:    Translation:Humans
  73. Hallinan ZP, Getz KA, Bierer BE. Compliance with results reporting at ClinicalTrials.gov. N Engl J Med. 2015 06 11; 372(24):2370. PMID: 26061854.
    Citations:    Fields:    Translation:Humans
  74. Winkler SJ, Witte E, Bierer BE. The Harvard Catalyst Common Reciprocal IRB Reliance Agreement: an innovative approach to multisite IRB review and oversight. Clin Transl Sci. 2015 Feb; 8(1):57-66. PMID: 25196592.
    Citations: 12     Fields:    Translation:Humans
  75. Bierer BE, Barnes M. Research misconduct involving noncompliance in human subjects research supported by the public health service: reconciling separate regulatory systems. Hastings Cent Rep. 2014 Jul-Aug; 44(4 Spec No):S2-26. PMID: 25043467.
    Citations: 1     Fields:    Translation:Humans
  76. Winkler SJ, Cagliero E, Witte E, Bierer BE. A distributed model: redefining a robust research subject advocacy program at the Harvard Clinical and Translational Science Center. Clin Transl Sci. 2014 Aug; 7(4):329-35. PMID: 24841488.
    Citations: 1     Fields:    Translation:Humans
  77. Kim MJ, Winkler SJ, Bierer BE, Wolf D. Harvard Catalyst | The Clinical Translational Science Center IND/IDE Consult Service: providing an IND/IDE consult service in a decentralized network of academic healthcare centers. Clin Transl Sci. 2014 Apr; 7(2):150-5. PMID: 24455986.
    Citations:    Fields:    
  78. Mello MM, Francer JK, Wilenzick M, Teden P, Bierer BE, Barnes M. Preparing for responsible sharing of clinical trial data. N Engl J Med. 2013 Oct 24; 369(17):1651-8. PMID: 24144394.
    Citations: 57     Fields:    
  79. Nelsen LL, Bierer BE. Biomedical innovation in academic institutions: mitigating conflict of interest. Sci Transl Med. 2011 Sep 14; 3(100):100cm26. PMID: 21918104.
    Citations: 2     Fields:    
  80. Weingart SN, Price J, Duncombe D, Connor M, Conley K, Conlin GJ, Sullivan AM, Powell M, Ponte PR, Bierer BE. Enhancing safety reporting in adult ambulatory oncology with a clinician champion: a practice innovation. J Nurs Care Qual. 2009 Jul-Sep; 24(3):203-10. PMID: 19525761.
    Citations: 4     Fields:    Translation:Humans
  81. Weingart SN, Price J, Duncombe D, Connor M, Sommer K, Conley KA, Bierer BE, Ponte PR. Patient-reported safety and quality of care in outpatient oncology. Jt Comm J Qual Patient Saf. 2007 Feb; 33(2):83-94. PMID: 17370919.
    Citations: 22     Fields:    Translation:Humans
  82. Morley SC, Sung J, Sun GP, Martelli MP, Bunnell SC, Bierer BE. Gelsolin overexpression alters actin dynamics and tyrosine phosphorylation of lipid raft-associated proteins in Jurkat T cells. Mol Immunol. 2007 Mar; 44(9):2469-80. PMID: 17178161.
    Citations: 9     Fields:    Translation:HumansCells
  83. Foley JE, Jung U, Miera A, Borenstein T, Mariotti J, Eckhaus M, Bierer BE, Fowler DH. Ex vivo rapamycin generates donor Th2 cells that potently inhibit graft-versus-host disease and graft-versus-tumor effects via an IL-4-dependent mechanism. J Immunol. 2005 Nov 01; 175(9):5732-43. PMID: 16237064.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  84. Bierer BE. Isolation and Differentiation of Stem and Progenitor Cells. Curr Protoc Immunol. 2005 Apr; 66(1):1. PMID: 29921114.
    Citations:    Fields:    
  85. Cristillo AD, Bierer BE. Regulation of CXCR4 expression in human T lymphocytes by calcium and calcineurin. Mol Immunol. 2003 Dec; 40(8):539-53. PMID: 14563373.
    Citations: 9     Fields:    Translation:HumansCells
  86. Salazar-Fontana LI, Barr V, Samelson LE, Bierer BE. CD28 engagement promotes actin polymerization through the activation of the small Rho GTPase Cdc42 in human T cells. J Immunol. 2003 Sep 01; 171(5):2225-32. PMID: 12928366.
    Citations: 30     Fields:    Translation:HumansCells
  87. Cristillo AD, Nie L, Macri MJ, Bierer BE. Cloning and characterization of N4WBP5A, an inducible, cyclosporine-sensitive, Nedd4-binding protein in human T lymphocytes. J Biol Chem. 2003 Sep 05; 278(36):34587-97. PMID: 12796489.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  88. Celeste Morley S, Sun GP, Bierer BE. Inhibition of actin polymerization enhances commitment to and execution of apoptosis induced by withdrawal of trophic support. J Cell Biochem. 2003 Apr 01; 88(5):1066-76. PMID: 12616543.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  89. Cristillo AD, Macri MJ, Bierer BE. Differential chemokine expression profiles in human peripheral blood T lymphocytes: dependence on T-cell coreceptor and calcineurin signaling. Blood. 2003 Jan 01; 101(1):216-25. PMID: 12393716.
    Citations: 8     Fields:    Translation:HumansCells
  90. Cristillo AD, Xiao X, Campbell-Malone R, Dimitrov DS, Bierer BE. Differences between CEM and human peripheral blood T lymphocytes in cAMP-dependent HIV viral fusion and CXCR4 expression. Exp Mol Pathol. 2002 Aug; 73(1):9-18. PMID: 12127049.
    Citations: 1     Fields:    Translation:HumansCells
  91. Cristillo AD, Highbarger HC, Dewar RL, Dimitrov DS, Golding H, Bierer BE. Up-regulation of HIV coreceptor CXCR4 expression in human T lymphocytes is mediated in part by a cAMP-responsive element. FASEB J. 2002 Mar; 16(3):354-64. PMID: 11874984.
    Citations: 15     Fields:    Translation:HumansCells
  92. Li TK, Baksh S, Cristillo AD, Bierer BE. Calcium- and FK506-independent interaction between the immunophilin FKBP51 and calcineurin. J Cell Biochem. 2002; 84(3):460-71. PMID: 11813252.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  93. Cristillo AD, Bierer BE. Identification of novel targets of immunosuppressive agents by cDNA-based microarray analysis. J Biol Chem. 2002 Feb 08; 277(6):4465-76. PMID: 11694517.
    Citations: 3     Fields:    Translation:HumansCells
  94. Martelli MP, Boomer J, Bu M, Bierer BE. T cell regulation of p62(dok) (Dok1) association with Crk-L. J Biol Chem. 2001 Dec 07; 276(49):45654-61. PMID: 11553620.
    Citations: 6     Fields:    Translation:HumansCells
  95. Winston DJ, Antin JH, Wolff SN, Bierer BE, Small T, Miller KB, Linker C, Kaizer H, Lazarus HM, Petersen FB, Cowan MJ, Ho WG, Wingard JR, Schiller GJ, Territo MC, Jiao J, Petrarca MA, Tonetta SA. A multicenter, randomized, double-blind comparison of different doses of intravenous immunoglobulin for prevention of graft-versus-host disease and infection after allogeneic bone marrow transplantation. Bone Marrow Transplant. 2001 Jul; 28(2):187-96. PMID: 11509937.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  96. Lin H, Martelli MP, Bierer BE. The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation. Int Immunol. 2001 Jan; 13(1):13-22. PMID: 11133830.
    Citations: 2     Fields:    Translation:HumansCells
  97. Salazar-Fontana LI, Bierer BE. T-lymphocyte coactivator molecules. Curr Opin Hematol. 2001 Jan; 8(1):5-11. PMID: 11138627.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  98. Morley SC, Bierer BE. The actin cytoskeleton, membrane lipid microdomains, and T cell signal transduction. Adv Immunol. 2001; 77:1-43. PMID: 11293114.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  99. Stillwell R, Bierer BE. T cell signal transduction and the role of CD7 in costimulation. Immunol Res. 2001; 24(1):31-52. PMID: 11485208.
    Citations: 17     Fields:    Translation:AnimalsCells
  100. Martelli MP, Lin H, Zhang W, Samelson LE, Bierer BE. Signaling via LAT (linker for T-cell activation) and Syk/ZAP70 is required for ERK activation and NFAT transcriptional activation following CD2 stimulation. Blood. 2000 Sep 15; 96(6):2181-90. PMID: 10979964.
    Citations: 16     Fields:    Translation:HumansCells
  101. Ouyang Y, Virasch N, Hao P, Aubrey MT, Mukerjee N, Bierer BE, Freed BM. Suppression of human IL-1beta, IL-2, IFN-gamma, and TNF-alpha production by cigarette smoke extracts. J Allergy Clin Immunol. 2000 Aug; 106(2):280-7. PMID: 10932071.
    Citations: 55     Fields:    Translation:HumansAnimals
  102. Posey SC, Martelli MP, Azuma T, Kwiatkowski DJ, Bierer BE. Failure of gelsolin overexpression to regulate lymphocyte apoptosis. Blood. 2000 Jun 01; 95(11):3483-8. PMID: 10828033.
    Citations: 6     Fields:    Translation:HumansCells
  103. Tirnauer JS, Bierer BE. EB1 proteins regulate microtubule dynamics, cell polarity, and chromosome stability. J Cell Biol. 2000 May 15; 149(4):761-6. PMID: 10811817.
    Citations: 98     Fields:    Translation:HumansAnimalsCells
  104. Tirnauer JS, O'Toole E, Berrueta L, Bierer BE, Pellman D. Yeast Bim1p promotes the G1-specific dynamics of microtubules. J Cell Biol. 1999 May 31; 145(5):993-1007. PMID: 10352017.
    Citations: 108     Fields:    Translation:HumansAnimalsCells
  105. Berrueta L, Tirnauer JS, Schuyler SC, Pellman D, Bierer BE. The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain. Curr Biol. 1999 Apr 22; 9(8):425-8. PMID: 10226031.
    Citations: 56     Fields:    Translation:HumansAnimalsCells
  106. Posey SC, Bierer BE. Actin stabilization by jasplakinolide enhances apoptosis induced by cytokine deprivation. J Biol Chem. 1999 Feb 12; 274(7):4259-65. PMID: 9933626.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  107. Slavik JM, Hutchcroft JE, Bierer BE. CD80 and CD86 are not equivalent in their ability to induce the tyrosine phosphorylation of CD28. J Biol Chem. 1999 Jan 29; 274(5):3116-24. PMID: 9915850.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  108. Slavik JM, Hutchcroft JE, Bierer BE. CD28/CTLA-4 and CD80/CD86 families: signaling and function. Immunol Res. 1999; 19(1):1-24. PMID: 10374692.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
  109. Hutchcroft JE, Slavik JM, Lin H, Watanabe T, Bierer BE. Uncoupling activation-dependent HS1 phosphorylation from nuclear factor of activated T cells transcriptional activation in Jurkat T cells: differential signaling through CD3 and the costimulatory receptors CD2 and CD28. J Immunol. 1998 Nov 01; 161(9):4506-12. PMID: 9794375.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  110. Berrueta L, Kraeft SK, Tirnauer JS, Schuyler SC, Chen LB, Hill DE, Pellman D, Bierer BE. The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules. Proc Natl Acad Sci U S A. 1998 Sep 01; 95(18):10596-601. PMID: 9724749.
    Citations: 59     Fields:    Translation:AnimalsCells
  111. Kivens WJ, Hunt SW, Mobley JL, Zell T, Dell CL, Bierer BE, Shimizu Y. Identification of a proline-rich sequence in the CD2 cytoplasmic domain critical for regulation of integrin-mediated adhesion and activation of phosphoinositide 3-kinase. Mol Cell Biol. 1998 Sep; 18(9):5291-307. PMID: 9710614.
    Citations: 14     Fields:    Translation:HumansCells
  112. Lin H, Hutchcroft JE, Andoniou CE, Kamoun M, Band H, Bierer BE. Association of p59(fyn) with the T lymphocyte costimulatory receptor CD2. Binding of the Fyn Src homology (SH) 3 domain is regulated by the Fyn SH2 domain. J Biol Chem. 1998 Jul 31; 273(31):19914-21. PMID: 9677430.
    Citations: 7     Fields:    Translation:HumansCells
  113. Dunussi-Joannopoulos K, Dranoff G, Weinstein HJ, Ferrara JL, Bierer BE, Croop JM. Gene immunotherapy in murine acute myeloid leukemia: granulocyte-macrophage colony-stimulating factor tumor cell vaccines elicit more potent antitumor immunity compared with B7 family and other cytokine vaccines. Blood. 1998 Jan 01; 91(1):222-30. PMID: 9414288.
    Citations: 21     Fields:    Translation:AnimalsCells
  114. Ballen KK, Gilliland DG, Guinan EC, Hsieh CC, Parsons SK, Rimm IJ, Ferrara JL, Bierer BE, Weinstein HJ, Antin JH. Bone marrow transplantation for therapy-related myelodysplasia: comparison with primary myelodysplasia. Bone Marrow Transplant. 1997 Nov; 20(9):737-43. PMID: 9384475.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  115. Trede NS, Warwick AB, Rosoff PM, Rohrer R, Bierer BE, Guinan E. Tacrolimus (FK506) in allogeneic bone marrow transplantation for severe aplastic anemia following orthotopic liver transplantation. Bone Marrow Transplant. 1997 Aug; 20(3):257-60. PMID: 9257897.
    Citations: 4     Fields:    Translation:Humans
  116. Wheeler C, Eickhoff C, Elias A, Ibrahim J, Ayash L, McCauley M, Mauch P, Schwartz G, Eder JP, Mazanet R, Ferrara J, Rimm IJ, Guinan E, Bierer B, Gilliland G, Churchill WH, Ault K, Parsons S, Antman K, Schnipper L, Tepler I, Gaynes L, Frei E, Kadin M, Antin J. High-dose cyclophosphamide, carmustine, and etoposide with autologous transplantation in Hodgkin's disease: a prognostic model for treatment outcomes. Biol Blood Marrow Transplant. 1997 Jun; 3(2):98-106. PMID: 9267670.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  117. Lee SJ, Wegner SA, McGarigle CJ, Bierer BE, Antin JH. Treatment of chronic graft-versus-host disease with clofazimine. Blood. 1997 Apr 01; 89(7):2298-302. PMID: 9116272.
    Citations: 10     Fields:    Translation:HumansCTClinical Trials
  118. Lehmann LE, Guinan EC, Halpern SL, Donovan MJ, Bierer BE, Parsons SK. Isolated testicular relapse in an adolescent 5 years following allogeneic bone marrow transplantation for acute myelogenous leukemia. Bone Marrow Transplant. 1997 Apr; 19(8):849-51. PMID: 9134181.
    Citations:    Fields:    Translation:Humans
  119. Sagoo JK, Fruman DA, Wesselborg S, Walsh CT, Bierer BE. Competitive inhibition of calcineurin phosphatase activity by its autoinhibitory domain. Biochem J. 1996 Dec 15; 320 ( Pt 3):879-84. PMID: 9003375.
    Citations: 16     Fields:    Translation:Cells
  120. Hutchcroft JE, Tsai B, Bierer BE. Differential phosphorylation of the T lymphocyte costimulatory receptor CD28. Activation-dependent changes and regulation by protein kinase C. J Biol Chem. 1996 Jun 07; 271(23):13362-70. PMID: 8662792.
    Citations: 3     Fields:    Translation:HumansCells
  121. Hutchcroft JE, Bierer BE. Signaling through CD28/CTLA-4 family receptors: puzzling participation of phosphatidylinositol-3 kinase. J Immunol. 1996 Jun 01; 156(11):4071-4. PMID: 8666770.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  122. Fay JW, Wingard JR, Antin JH, Collins RH, Piñeiro LA, Blazar BR, Saral R, Bierer BE, Przepiorka D, Fitzsimmons WE, Maher RM, Weisdorf DJ. FK506 (Tacrolimus) monotherapy for prevention of graft-versus-host disease after histocompatible sibling allogenic bone marrow transplantation. Blood. 1996 Apr 15; 87(8):3514-9. PMID: 8605372.
    Citations: 16     Fields:    Translation:HumansCTClinical Trials
  123. Wesselborg S, Fruman DA, Sagoo JK, Bierer BE, Burakoff SJ. Identification of a physical interaction between calcineurin and nuclear factor of activated T cells (NFATp). J Biol Chem. 1996 Jan 19; 271(3):1274-7. PMID: 8576111.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  124. Yeh WC, Li TK, Bierer BE, McKnight SL. Identification and characterization of an immunophilin expressed during the clonal expansion phase of adipocyte differentiation. Proc Natl Acad Sci U S A. 1995 Nov 21; 92(24):11081-5. PMID: 7479941.
    Citations: 19     Fields:    Translation:AnimalsCells
  125. Yeh WC, Bierer BE, McKnight SL. Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells. Proc Natl Acad Sci U S A. 1995 Nov 21; 92(24):11086-90. PMID: 7479942.
    Citations: 75     Fields:    Translation:AnimalsCells
  126. Hutchcroft JE, Franklin DP, Tsai B, Harrison-Findik D, Varticovski L, Bierer BE. Phorbol ester treatment inhibits phosphatidylinositol 3-kinase activation by, and association with, CD28, a T-lymphocyte surface receptor. Proc Natl Acad Sci U S A. 1995 Sep 12; 92(19):8808-12. PMID: 7568022.
    Citations: 5     Fields:    Translation:HumansCells
  127. Fruman DA, Pai SY, Burakoff SJ, Bierer BE. Characterization of a mutant calcineurin A alpha gene expressed by EL4 lymphoma cells. Mol Cell Biol. 1995 Jul; 15(7):3857-63. PMID: 7791792.
    Citations: 12     Fields:    Translation:AnimalsCells
  128. Bierer BE. Mechanisms of action of immunosuppressive agents: cyclosporin A, FK506, and rapamycin. Proc Assoc Am Physicians. 1995 Apr; 107(1):28-40. PMID: 8630742.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  129. Fruman DA, Bierer BE, Benes JE, Burakoff SJ, Austen KF, Katz HR. The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells. J Immunol. 1995 Feb 15; 154(4):1846-51. PMID: 7530743.
    Citations: 12     Fields:    Translation:AnimalsCells
  130. Fruman DA, Wood MA, Gjertson CK, Katz HR, Burakoff SJ, Bierer BE. FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells. Eur J Immunol. 1995 Feb; 25(2):563-71. PMID: 7533090.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  131. Liu SJ, Hahn WC, Bierer BE, Golan DE. Intracellular mediators regulate CD2 lateral diffusion and cytoplasmic Ca2+ mobilization upon CD2-mediated T cell activation. Biophys J. 1995 Feb; 68(2):459-70. PMID: 7696499.
    Citations: 7     Fields:    Translation:HumansCells
  132. Pai SY, Fruman DA, Leong T, Neuberg D, Rosano TG, McGarigle C, Antin JH, Bierer BE. Inhibition of calcineurin phosphatase activity in adult bone marrow transplant patients treated with cyclosporine A. Blood. 1994 Dec 01; 84(11):3974-9. PMID: 7949153.
    Citations: 5     Fields:    Translation:HumansCells
  133. Holländer GA, Fruman DA, Bierer BE, Burakoff SJ. Disruption of T cell development and repertoire selection by calcineurin inhibition in vivo. Transplantation. 1994 Nov 15; 58(9):1037-43. PMID: 7526495.
    Citations: 2     Fields:    Translation:AnimalsCells
  134. Calvo V, Wood M, Gjertson C, Vik T, Bierer BE. Activation of 70-kDa S6 kinase, induced by the cytokines interleukin-3 and erythropoietin and inhibited by rapamycin, is not an absolute requirement for cell proliferation. Eur J Immunol. 1994 Nov; 24(11):2664-71. PMID: 7957559.
    Citations: 8     Fields:    Translation:AnimalsCells
  135. Pai SY, Calvo V, Wood M, Bierer BE. Cross-linking CD28 leads to activation of 70-kDa S6 kinase. Eur J Immunol. 1994 Oct; 24(10):2364-8. PMID: 7523138.
    Citations: 5     Fields:    Translation:HumansCells
  136. Menu E, Tsai BC, Bothwell AL, Sims PJ, Bierer BE. CD59 costimulation of T cell activation. CD58 dependence and requirement for glycosylation. J Immunol. 1994 Sep 15; 153(6):2444-56. PMID: 7521361.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  137. Holländer GA, Bierer BE, Burakoff SJ. Molecular and biological actions of cyclosporin A and FK506 on T cell development and function. Transfus Sci. 1994 Sep; 15(3):207-20. PMID: 10155542.
    Citations: 3     Translation:HumansAnimalsCells
  138. Antin JH, Weinstein HJ, Guinan EC, McCarthy P, Bierer BE, Gilliland DG, Parsons SK, Ballen KK, Rimm IJ, Falzarano G, et al. Recombinant human interleukin-1 receptor antagonist in the treatment of steroid-resistant graft-versus-host disease. Blood. 1994 Aug 15; 84(4):1342-8. PMID: 8049450.
    Citations: 31     Fields:    Translation:HumansCells
  139. Collins TL, Kassner PD, Bierer BE, Burakoff SJ. Adhesion receptors in lymphocyte activation. Curr Opin Immunol. 1994 Jun; 6(3):385-93. PMID: 7917106.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  140. Hutchcroft JE, Bierer BE. Activation-dependent phosphorylation of the T-lymphocyte surface receptor CD28 and associated proteins. Proc Natl Acad Sci U S A. 1994 Apr 12; 91(8):3260-4. PMID: 7512728.
    Citations: 15     Fields:    Translation:HumansCells
  141. Fruman DA, Burakoff SJ, Bierer BE. Immunophilins in protein folding and immunosuppression. FASEB J. 1994 Apr 01; 8(6):391-400. PMID: 7513288.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  142. Bierer BE. Biology of cyclosporin A and FK506. Prog Clin Biol Res. 1994; 390:203-23. PMID: 7536944.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  143. Bierer BE. Cyclosporin A, FK506, and rapamycin: binding to immunophilins and biological action. Chem Immunol. 1994; 59:128-55. PMID: 7524531.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  144. Hendrickson BA, Zhang W, Craig RJ, Jin YJ, Bierer BE, Burakoff S, DiLella AG. Structural organization of the genes encoding human and murine FK506-binding protein (FKBP) 13 and comparison to FKBP1. Gene. 1993 Dec 08; 134(2):271-5. PMID: 7505249.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  145. Hahn WC, Bierer BE. Separable portions of the CD2 cytoplasmic domain involved in signaling and ligand avidity regulation. J Exp Med. 1993 Nov 01; 178(5):1831-6. PMID: 7901319.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  146. Bierer BE, Holländer G, Fruman D, Burakoff SJ. Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology. Curr Opin Immunol. 1993 Oct; 5(5):763-73. PMID: 7694595.
    Citations: 25     Fields:    Translation:AnimalsCells
  147. Nigam SK, Jin YJ, Jin MJ, Bush KT, Bierer BE, Burakoff SJ. Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum. Biochem J. 1993 Sep 01; 294 ( Pt 2):511-5. PMID: 8373365.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  148. Bierer BE, Hahn WC. T cell adhesion, avidity regulation and signaling: a molecular analysis of CD2. Semin Immunol. 1993 Aug; 5(4):249-61. PMID: 7693022.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  149. Wheeler C, Strawderman M, Ayash L, Churchill WH, Bierer BE, Elias A, Gilliland DG, Antman K, Guinan EC, Eder JP, et al. Prognostic factors for treatment outcome in autotransplantation of intermediate-grade and high-grade non-Hodgkin's lymphoma with cyclophosphamide, carmustine, and etoposide. J Clin Oncol. 1993 Jun; 11(6):1085-91. PMID: 8099120.
    Citations: 8     Fields:    Translation:Humans
  150. Hahn WC, Menzin E, Saito T, Germain RN, Bierer BE. The complete sequences of plasmids pFNeo and pMH-Neo: convenient expression vectors for high-level expression of eukaryotic genes in hematopoietic cell lines. Gene. 1993 May 30; 127(2):267-8. PMID: 8500769.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  151. Dutz JP, Fruman DA, Burakoff SJ, Bierer BE. A role for calcineurin in degranulation of murine cytotoxic T lymphocytes. J Immunol. 1993 Apr 01; 150(7):2591-8. PMID: 7681074.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  152. Hahn WC, Burakoff SJ, Bierer BE. Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58. J Immunol. 1993 Apr 01; 150(7):2607-19. PMID: 7681075.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  153. Offringa R, Bierer BE. Association of CD2 with tubulin. Evidence for a role of the cytoskeleton in T cell activation. J Biol Chem. 1993 Mar 05; 268(7):4979-88. PMID: 8095265.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  154. Goust JM, Bierer B. Cell-mediated immunity. Immunol Ser. 1993; 58:187-212. PMID: 8424973.
    Citations:    Fields:    Translation:HumansAnimalsCells
  155. Collins TL, Hahn WC, Bierer BE, Burakoff SJ. CD4, CD8 and CD2 in T cell adhesion and signaling. Curr Top Microbiol Immunol. 1993; 184:223-33. PMID: 7906216.
    Citations:    Fields:    Translation:HumansAnimalsCells
  156. Fruman DA, Mather PE, Burakoff SJ, Bierer BE. Correlation of calcineurin phosphatase activity and programmed cell death in murine T cell hybridomas. Eur J Immunol. 1992 Oct; 22(10):2513-7. PMID: 1382988.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  157. Kaye RE, Fruman DA, Bierer BE, Albers MW, Zydowsky LD, Ho SI, Jin YJ, Castells MC, Schreiber SL, Walsh CT, et al. Effects of cyclosporin A and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12. Proc Natl Acad Sci U S A. 1992 Sep 15; 89(18):8542-6. PMID: 1382293.
    Citations: 18     Fields:    Translation:AnimalsCells
  158. Arceci RJ, Stieglitz K, Bierer BE. Immunosuppressants FK506 and rapamycin function as reversal agents of the multidrug resistance phenotype. Blood. 1992 Sep 15; 80(6):1528-36. PMID: 1381629.
    Citations: 36     Fields:    Translation:HumansCells
  159. Calvo V, Crews CM, Vik TA, Bierer BE. Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin. Proc Natl Acad Sci U S A. 1992 Aug 15; 89(16):7571-5. PMID: 1380162.
    Citations: 33     Fields:    Translation:AnimalsCells
  160. Price DJ, Grove JR, Calvo V, Avruch J, Bierer BE. Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase. Science. 1992 Aug 14; 257(5072):973-7. PMID: 1380182.
    Citations: 165     Fields:    Translation:AnimalsCells
  161. Hahn WC, Rosenstein Y, Calvo V, Burakoff SJ, Bierer BE. A distinct cytoplasmic domain of CD2 regulates ligand avidity and T-cell responsiveness to antigen. Proc Natl Acad Sci U S A. 1992 Aug 01; 89(15):7179-83. PMID: 1353888.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  162. Hahn WC, Menu E, Bothwell AL, Sims PJ, Bierer BE. Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59. Science. 1992 Jun 26; 256(5065):1805-7. PMID: 1377404.
    Citations: 50     Fields:    Translation:HumansAnimalsCells
  163. Jin YJ, Burakoff SJ, Bierer BE. Molecular cloning of a 25-kDa high affinity rapamycin binding protein, FKBP25. J Biol Chem. 1992 Jun 05; 267(16):10942-5. PMID: 1375932.
    Citations: 27     Fields:    Translation:HumansCells
  164. Höllsberg P, Wucherpfennig KW, Ausubel LJ, Calvo V, Bierer BE, Hafler DA. Characterization of HTLV-I in vivo infected T cell clones. IL-2-independent growth of nontransformed T cells. J Immunol. 1992 May 15; 148(10):3256-63. PMID: 1374452.
    Citations: 17     Fields:    Translation:HumansCells
  165. Fruman DA, Klee CB, Bierer BE, Burakoff SJ. Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. Proc Natl Acad Sci U S A. 1992 May 01; 89(9):3686-90. PMID: 1373887.
    Citations: 171     Fields:    Translation:HumansCells
  166. Calvo V, Bierer BE, Vik TA. T cell receptor activation of a ribosomal S6 kinase activity. Eur J Immunol. 1992 Feb; 22(2):457-62. PMID: 1537381.
    Citations: 4     Fields:    Translation:HumansCells
  167. Bierer BE, Jin YJ, Fruman DA, Calvo V, Burakoff SJ. FK 506 and rapamycin: molecular probes of T-lymphocyte activation. Transplant Proc. 1991 Dec; 23(6):2850-5. PMID: 1721296.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  168. Rosenstein Y, Park JK, Hahn WC, Rosen FS, Bierer BE, Burakoff SJ. CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1. Nature. 1991 Nov 21; 354(6350):233-5. PMID: 1683685.
    Citations: 55     Fields:    Translation:HumansAnimalsCells
  169. Antin JH, Bierer BE, Smith BR, Ferrara J, Guinan EC, Sieff C, Golan DE, Macklis RM, Tarbell NJ, Lynch E, et al. Selective depletion of bone marrow T lymphocytes with anti-CD5 monoclonal antibodies: effective prophylaxis for graft-versus-host disease in patients with hematologic malignancies. Blood. 1991 Oct 15; 78(8):2139-49. PMID: 1717080.
    Citations: 11     Fields:    Translation:HumansCells
  170. Jin YJ, Albers MW, Lane WS, Bierer BE, Schreiber SL, Burakoff SJ. Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13. Proc Natl Acad Sci U S A. 1991 Aug 01; 88(15):6677-81. PMID: 1713687.
    Citations: 47     Fields:    Translation:HumansCells
  171. Hahn WC, Rosenstein Y, Burakoff SJ, Bierer BE. Interaction of CD2 with its ligand lymphocyte function-associated antigen-3 induces adenosine 3',5'-cyclic monophosphate production in T lymphocytes. J Immunol. 1991 Jul 01; 147(1):14-21. PMID: 1711070.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  172. Park JK, Rosenstein YJ, Remold-O'Donnell E, Bierer BE, Rosen FS, Burakoff SJ. Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott-Aldrich syndrome. Nature. 1991 Apr 25; 350(6320):706-9. PMID: 2023632.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  173. Bierer BE, Schreiber SL, Burakoff SJ. The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation. Eur J Immunol. 1991 Feb; 21(2):439-45. PMID: 1705513.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  174. Bierer BE, Burakoff SJ. T cell receptors: adhesion and signaling. Adv Cancer Res. 1991; 56:49-76. PMID: 2028842.
    Citations: 4     Fields:    Translation:HumansAnimals
  175. Bierer BE, Mattila PS, Standaert RF, Herzenberg LA, Burakoff SJ, Crabtree G, Schreiber SL. Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin. Proc Natl Acad Sci U S A. 1990 Dec; 87(23):9231-5. PMID: 2123553.
    Citations: 157     Fields: