Harvard Catalyst Profiles

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Michael Richard Filbin, M.D.

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selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Rhee C, Filbin M, Klompas M. Measuring Diagnostic Accuracy for Infection in Patients Treated for Sepsis: An Important but Challenging Exercise. Clin Infect Dis. 2023 Feb 20. PMID: 36804679.
    Citations:    Fields:    
  2. Lee AH, McEvoy DS, Stump T, Stevens R, Deng H, Rubins D, Filbin M, Hayes BD, Rhee C, Dutta S. Implementation of an Electronic Alert to Improve Timeliness of Second Dose Antibiotics for Patients With Suspected Serious Infections in the Emergency Department: A Quasi-Randomized Controlled Trial. Ann Emerg Med. 2023 Jan 18. PMID: 36669909.
    Citations:    Fields:    
  3. Parthasarathy U, Kuang Y, Thakur G, Hogan JD, Wyche TP, Norton JE, Killough JR, Sana TR, Beakes C, Shyong B, Zhang RN, Gutierrez DA, Filbin M, Christiani DC, Therien AG, Woelk CH, White CH, Martinelli R. Distinct subsets of neutrophils crosstalk with cytokines and metabolites in patients with sepsis. iScience. 2023 Feb 17; 26(2):105948. PMID: 36756375; PMCID: PMC9900520.
    Citations:    
  4. Filbin MR. Insights into Endotheliopathy in COVID-19. Am J Respir Crit Care Med. 2022 10 15; 206(8):926-928. PMID: 35819867; PMCID: PMC9801991.
    Citations:    Fields:    
  5. Shapiro NI, Filbin MR, Hou PC, Kurz MC, Han JH, Aufderheide TP, Ward MA, Pulia MS, Birkhahn RH, Diaz JL, Hughes TL, Harsch MR, Bell A, Suarez-Cuervo C, Sambursky R. Diagnostic Accuracy of a Bacterial and Viral Biomarker Point-of-Care Test in the Outpatient Setting. JAMA Netw Open. 2022 10 03; 5(10):e2234588. PMID: 36255727; PMCID: PMC9579916.
    Citations:    Fields:    Translation:Humans
  6. LaSalle TJ, Gonye ALK, Freeman SS, Kaplonek P, Gushterova I, Kays KR, Manakongtreecheep K, Tantivit J, Rojas-Lopez M, Russo BC, Sharma N, Thomas MF, Lavin-Parsons KM, Lilly BM, Mckaig BN, Charland NC, Khanna HK, Lodenstein CL, Margolin JD, Blaum EM, Lirofonis PB, Revach OY, Mehta A, Sonny A, Bhattacharyya RP, Parry BA, Goldberg MB, Alter G, Filbin MR, Villani AC, Hacohen N, Sade-Feldman M. Longitudinal characterization of circulating neutrophils uncovers phenotypes associated with severity in hospitalized COVID-19 patients. Cell Rep Med. 2022 10 18; 3(10):100779. PMID: 36208629; PMCID: PMC9510054.
    Citations: 3     Fields:    Translation:HumansCells
  7. Dutta S, McEvoy DS, Rubins DM, Dighe AS, Filbin MR, Rhee C. Clinical decision support improves blood culture collection before intravenous antibiotic administration in the emergency department. J Am Med Inform Assoc. 2022 09 12; 29(10):1705-1714. PMID: 35877074; PMCID: PMC9471721.
    Citations:    Fields:    
  8. Wang C, Li Y, Kaplonek P, Gentili M, Fischinger S, Bowman KA, Sade-Feldman M, Kays KR, Regan J, Flynn JP, Goldberg MB, Hacohen N, Filbin MR, Lauffenburger DA, Alter G, Li JZ. The Kinetics of SARS-CoV-2 Antibody Development Is Associated with Clearance of RNAemia. mBio. 2022 08 30; 13(4):e0157722. PMID: 35762593; PMCID: PMC9426503.
    Citations:    Fields:    
  9. Leisman DE, Mehta A, Thompson BT, Hacohen N, Filbin MR, Goldberg MB. Reply to Akin et al.: High Renin Concentrations in Severe COVID-19 Are Indicative for a Hypo-Renin-Angiotensin-System State. Am J Respir Crit Care Med. 2022 05 15; 205(10):1253-1254. PMID: 35348420; PMCID: PMC9872805.
    Citations:    Fields:    Translation:HumansCells
  10. Yun BJ, Baugh JJ, Dutta S, Brown DFM, Temin ES, Turbett SE, Shenoy ES, Biddinger PD, Dighe AS, Kays K, Parry BA, McKaig B, Beakes C, Margolin J, Russell N, Lodenstein C, McEvoy DS, Filbin MR. COVID-19 Seroprevalence in ED Health Care Professionals Study: A Cross-Sectional Study. J Emerg Nurs. 2022 Jul; 48(4):417-422. PMID: 35697551; PMCID: PMC9023353.
    Citations:    Fields:    Translation:HumansCells
  11. Junqueira C, Crespo Â, Ranjbar S, de Lacerda LB, Lewandrowski M, Ingber J, Parry B, Ravid S, Clark S, Schrimpf MR, Ho F, Beakes C, Margolin J, Russell N, Kays K, Boucau J, Das Adhikari U, Vora SM, Leger V, Gehrke L, Henderson LA, Janssen E, Kwon D, Sander C, Abraham J, Goldberg MB, Wu H, Mehta G, Bell S, Goldfeld AE, Filbin MR, Lieberman J. Fc?R-mediated SARS-CoV-2 infection of monocytes activates inflammation. Nature. 2022 06; 606(7914):576-584. PMID: 35385861.
    Citations: 22     Fields:    Translation:HumansCells
  12. Prasad V, Reisner AT, Lynch JC, Filbin MR, Heldt T. Modeling of Usual Care: Vasopressor Initiation for Sepsis With Hypotension. Front Med (Lausanne). 2022; 9:715856. PMID: 35360743; PMCID: PMC8963410.
    Citations:    
  13. Leisman DE, Mehta A, Thompson BT, Charland NC, Gonye ALK, Gushterova I, Kays KR, Khanna HK, LaSalle TJ, Lavin-Parsons KM, Lilley BM, Lodenstein CL, Manakongtreecheep K, Margolin JD, McKaig BN, Rojas-Lopez M, Russo BC, Sharma N, Tantivit J, Thomas MF, Parry BA, Villani AC, Sade-Feldman M, Hacohen N, Filbin MR, Goldberg MB. Alveolar, Endothelial, and Organ Injury Marker Dynamics in Severe COVID-19. Am J Respir Crit Care Med. 2022 03 01; 205(5):507-519. PMID: 34878969; PMCID: PMC8906476.
    Citations: 5     Fields:    Translation:HumansCells
  14. Fenyves BG, Mehta A, Kays KR, Beakes C, Margolin J, Goldberg MB, Hacohen N, Filbin MR. Plasma P-selectin is an early marker of thromboembolism in COVID-19. Am J Hematol. 2021 12 01; 96(12):E468-E471. PMID: 34622480.
    Citations: 2     Fields:    Translation:HumansCells
  15. Kaplonek P, Wang C, Bartsch Y, Fischinger S, Gorman MJ, Bowman K, Kang J, Dayal D, Martin P, Nowak RP, Villani AC, Hsieh CL, Charland NC, Gonye ALK, Gushterova I, Khanna HK, LaSalle TJ, Lavin-Parsons KM, Lilley BM, Lodenstein CL, Manakongtreecheep K, Margolin JD, McKaig BN, Rojas-Lopez M, Russo BC, Sharma N, Tantivit J, Thomas MF, Sade-Feldman M, Feldman J, Julg B, Nilles EJ, Musk ER, Menon AS, Fischer ES, McLellan JS, Schmidt A, Goldberg MB, Filbin MR, Hacohen N, Lauffenburger DA, Alter G. Early cross-coronavirus reactive signatures of humoral immunity against COVID-19. Sci Immunol. 2021 Oct 15; 6(64):eabj2901. PMID: 34652962; PMCID: PMC8943686.
    Citations: 23     Fields:    Translation:HumansCells
  16. LaSalle TJ, Gonye ALK, Freeman SS, Kaplonek P, Gushterova I, Kays KR, Manakongtreecheep K, Tantivit J, Rojas-Lopez M, Russo BC, Sharma N, Thomas MF, Lavin-Parsons KM, Lilly BM, Mckaig BN, Charland NC, Khanna HK, Lodenstein CL, Margolin JD, Blaum EM, Lirofonis PB, Sonny A, Bhattacharyya RP, Parry BA, Goldberg MB, Alter G, Filbin MR, Villani AC, Hacohen N, Sade-Feldman M. Longitudinal characterization of circulating neutrophils uncovers distinct phenotypes associated with disease severity in hospitalized COVID-19 patients. bioRxiv. 2021 Oct 05. PMID: 34642692; PMCID: PMC8509090.
    Citations: 1     
  17. Page B, Klompas M, Chan C, Filbin MR, Dutta S, McEvoy DS, Clark R, Leibowitz M, Rhee C. Surveillance for Healthcare-Associated Infections: Hospital-Onset Adult Sepsis Events Versus Current Reportable Conditions. Clin Infect Dis. 2021 09 15; 73(6):1013-1019. PMID: 33780544.
    Citations: 1     Fields:    Translation:HumansCells
  18. Liteplo AS, Schleifer J, Marill KA, Huang CK, Gouker SK, Ratanski D, Diamond E, Filbin MR, Shokoohi H. Carotid Ultrasound in Assessing Fluid Responsiveness in Patients with Hypotension and Suspected Sepsis. Shock. 2021 09 01; 56(3):419-424. PMID: 33577247.
    Citations:    Fields:    Translation:Humans
  19. Junqueira C, Crespo Â, Ranjbar S, Lewandrowski M, Ingber J, de Lacerda LB, Parry B, Ravid S, Clark S, Ho F, Vora SM, Leger V, Beakes C, Margolin J, Russell N, Kays K, Gehrke L, Adhikari UD, Henderson L, Janssen E, Kwon D, Sander C, Abraham J, Filbin M, Goldberg MB, Wu H, Mehta G, Bell S, Goldfeld AE, Lieberman J. SARS-CoV-2 infects blood monocytes to activate NLRP3 and AIM2 inflammasomes, pyroptosis and cytokine release. Res Sq. 2021 Aug 11. PMID: 34401873; PMCID: PMC8366805.
    Citations:    
  20. Leisman DE, Mehta A, Li Y, Kays KR, Li JZ, Filbin MR, Goldberg MB. Vasopressin infusion in COVID-19 critical illness is not associated with impaired viral clearance: a pilot study. Br J Anaesth. 2021 10; 127(4):e146-e148. PMID: 34399981; PMCID: PMC8289704.
    Citations: 3     Fields:    Translation:HumansCells
  21. Fenyves BG, Mehta A, Kays KR, Goldberg MB, Hacohen N, Filbin MR. Plasma P-selectin is an early marker of thromboembolism in COVID-19. medRxiv. 2021 Jul 14. PMID: 34282425.
    Citations:    
  22. Li Y, Schneider AM, Mehta A, Sade-Feldman M, Kays KR, Gentili M, Charland NC, Gonye AL, Gushterova I, Khanna HK, LaSalle TJ, Lavin-Parsons KM, Lilley BM, Lodenstein CL, Manakongtreecheep K, Margolin JD, McKaig BN, Parry BA, Rojas-Lopez M, Russo BC, Sharma N, Tantivit J, Thomas MF, Regan J, Flynn JP, Villani AC, Hacohen N, Goldberg MB, Filbin MR, Li JZ. SARS-CoV-2 viremia is associated with distinct proteomic pathways and predicts COVID-19 outcomes. J Clin Invest. 2021 07 01; 131(13). PMID: 34196300; PMCID: PMC8245177.
    Citations: 25     Fields:    Translation:HumansCellsPHPublic Health
  23. Hayden EM, Borczuk P, Dutta S, Liu SW, White BA, Lavin-Parsons K, Zheng H, Filbin MR, Zachrison KS. Can video-based telehealth examinations of the abdomen safely determine the need for imaging? J Telemed Telecare. 2021 Jun 18; 1357633X211023346. PMID: 34142893.
    Citations: 1     Fields:    
  24. Albala L, Loesche MA, Hayes BD, McEvoy DS, Filbin M, Dutta S, Eyre AJ. Sedation - Effects of disorders of abuse on therapeutic efficacy (SEDATE): A retrospective cohort study. Am J Emerg Med. 2021 Nov; 49:294-299. PMID: 34182272.
    Citations:    Fields:    Translation:Humans
  25. Reyes M, Filbin MR, Bhattacharyya RP, Sonny A, Mehta A, Billman K, Kays KR, Pinilla-Vera M, Benson ME, Cosimi LA, Hung DT, Levy BD, Villani AC, Sade-Feldman M, Baron RM, Goldberg MB, Blainey PC, Hacohen N. Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro. Sci Transl Med. 2021 06 16; 13(598). PMID: 34103408; PMCID: PMC8432955.
    Citations: 15     Fields:    Translation:HumansCells
  26. Kragstrup TW, Singh HS, Grundberg I, Nielsen AL, Rivellese F, Mehta A, Goldberg MB, Filbin MR, Qvist P, Bibby BM. Plasma ACE2 predicts outcome of COVID-19 in hospitalized patients. PLoS One. 2021; 16(6):e0252799. PMID: 34086837; PMCID: PMC8177449.
    Citations: 29     Fields:    Translation:HumansCells
  27. Kaplonek P, Wang C, Bartsch Y, Fischinger S, Gorman MJ, Bowman K, Kang J, Dayal D, Martin P, Nowak R, Hsieh CL, Feldman J, Julg B, Nilles EJ, Musk ER, Menon AS, Fischer ES, McLellan JS, Schmidt A, Goldberg MB, Filbin M, Hacohen N, Lauffenburger DA, Alter G. Early cross-coronavirus reactive signatures of protective humoral immunity against COVID-19. bioRxiv. 2021 May 12. PMID: 34013263.
    Citations: 1     
  28. Filbin MR, Mehta A, Schneider AM, Kays KR, Guess JR, Gentili M, Fenyves BG, Charland NC, Gonye ALK, Gushterova I, Khanna HK, LaSalle TJ, Lavin-Parsons KM, Lilley BM, Lodenstein CL, Manakongtreecheep K, Margolin JD, McKaig BN, Rojas-Lopez M, Russo BC, Sharma N, Tantivit J, Thomas MF, Gerszten RE, Heimberg GS, Hoover PJ, Lieb DJ, Lin B, Ngo D, Pelka K, Reyes M, Smillie CS, Waghray A, Wood TE, Zajac AS, Jennings LL, Grundberg I, Bhattacharyya RP, Parry BA, Villani AC, Sade-Feldman M, Hacohen N, Goldberg MB. Longitudinal proteomic analysis of severe COVID-19 reveals survival-associated signatures, tissue-specific cell death, and cell-cell interactions. Cell Rep Med. 2021 05 18; 2(5):100287. PMID: 33969320; PMCID: PMC8091031.
    Citations: 38     Fields:    
  29. Regan J, Flynn JP, Rosenthal A, Jordan H, Li Y, Chishti R, Giguel F, Corry H, Coxen K, Fajnzylber J, Gillespie E, Kuritzkes DR, Hacohen N, Goldberg MB, Filbin MR, Yu XG, Baden L, Ribeiro RM, Perelson AS, Conway JM, Li JZ. Viral Load Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 in Hospitalized Individuals With Coronavirus Disease 2019. Open Forum Infect Dis. 2021 Aug; 8(8):ofab153. PMID: 34430669; PMCID: PMC8083268.
    Citations: 8     
  30. Junqueira C, Crespo Â, Ranjbar S, Ingber J, Parry B, Ravid S, de Lacerda LB, Lewandrowski M, Clark S, Ho F, Vora SM, Leger V, Beakes C, Margolin J, Russell N, Gehrke L, Adhikari UD, Henderson L, Janssen E, Kwon D, Sander C, Abraham J, Filbin M, Goldberg MB, Wu H, Mehta G, Bell S, Goldfeld AE, Lieberman J. SARS-CoV-2 infects blood monocytes to activate NLRP3 and AIM2 inflammasomes, pyroptosis and cytokine release. medRxiv. 2021 Mar 08. PMID: 33758872; PMCID: PMC7987031.
    Citations: 1     
  31. Li Y, Schneider AM, Mehta A, Sade-Feldman M, Kays KR, Gentili M, Charland NC, Gonye ALK, Gushterova I, Khanna HK, LaSalle TJ, Lavin-Parsons KM, Lilly BM, Lodenstein CL, Manakongtreecheep K, Margolin JD, McKaig BN, Parry BA, Rojas-Lopez M, Russo BC, Sharma N, Tantivit J, Thomas MF, Regan J, Flynn JP, Villani AC, Hacohen N, Goldberg MB, Filbin MR, Li JZ. SARS-CoV-2 Viremia is Associated with Distinct Proteomic Pathways and Predicts COVID-19 Outcomes. medRxiv. 2021 Feb 26. PMID: 33655257; PMCID: PMC7924277.
    Citations:    
  32. Self WH, Semler MW, Leither LM, Casey JD, Angus DC, Brower RG, Chang SY, Collins SP, Eppensteiner JC, Filbin MR, Files DC, Gibbs KW, Ginde AA, Gong MN, Harrell FE, Hayden DL, Hough CL, Johnson NJ, Khan A, Lindsell CJ, Matthay MA, Moss M, Park PK, Rice TW, Robinson BRH, Schoenfeld DA, Shapiro NI, Steingrub JS, Ulysse CA, Weissman A, Yealy DM, Thompson BT, Brown SM, Steingrub J, Smithline H, Tiru B, Tidswell M, Kozikowski L, Thornton-Thompson S, De Souza L, Hou P, Baron R, Massaro A, Aisiku I, Fredenburgh L, Seethala R, Johnsky L, Riker R, Seder D, May T, Baumann M, Eldridge A, Lord C, Shapiro N, Talmor D, O’Mara T, Kirk C, Harrison K, Kurt L, Schermerhorn M, Banner-Goodspeed V, Boyle K, Dubosh N, Filbin M, Hibbert K, Parry B, Lavin-Parsons K, Pulido N, Lilley B, Lodenstein C, Margolin J, Brait K, Jones A, Galbraith J, Peacock R, Nandi U, Wachs T, Matthay M, Liu K, Kangelaris K, Wang R, Calfee C, Yee K, Hendey G, Chang S, Lim G, Qadir N, Tam A, Beutler R, Levitt J, Wilson J, Rogers A, Vojnik R, Roque J, Albertson T, Chenoweth J, Adams J, Pearson S, Juarez M, Almasri E, Fayed M, Hughes A, Hillard S, Huebinger R, Wang H, Vidales E, Patel B, Ginde A, Moss M, Baduashvili A, McKeehan J, Finck L, Higgins C, Howell M, Douglas I, Haukoos J, Hiller T, Lyle C, Cupelo A, Caruso E, Camacho C, Gravitz S, Finigan J, Griesmer C, Park P, Hyzy R, Nelson K, McDonough K, Olbrich N, Williams M, Kapoor R, Nash J, Willig M, Ford H, Gardner-Gray J, Ramesh M, Moses M, Ng Gong M, Aboodi M, Asghar A, Amosu O, Torres M, Kaur S, Chen JT, Hope A, Lopez B, Rosales K, Young You J, Mosier J, Hypes C, Natt B, Borg B, Salvagio Campbell E, Hite RD, Hudock K, Cresie A, Alhasan F, Gomez-Arroyo J, Duggal A, Mehkri O, Hastings A, Sahoo D, Abi Fadel F, Gole S, Shaner V, Wimer A, Meli Y, King A, Terndrup T, Exline M, Pannu S, Robart E, Karow S, Hough C, Robinson B, Johnson N, Henning D, Campo M, Gundel S, Seghal S, Katsandres S, Dean S, Khan A, Krol O, Jouzestani M, Huynh P, Weissman A, Yealy D, Scholl D, Adams P, McVerry B, Huang D, Angus D, Schooler J, Moore S, Files C, Miller C, Gibbs K, LaRose M, Flores L, Koehler L, Morse C, Sanders J, Langford C, Nanney K, MdalaGausi M, Yeboah P, Morris P, Sturgill J, Seif S, Cassity E, Dhar S, de Wit M, Mason J, Goodwin A, Hall G, Grady A, Chamberlain A, Brown S, Bledsoe J, Leither L, Peltan I, Starr N, Fergus M, Aston V, Montgomery Q, Smith R, Merrill M, Brown K, Armbruster B, Harris E, Middleton E, Paine R, Johnson S, Barrios M, Eppensteiner J, Limkakeng A, McGowan L, Porter T, Bouffler A, Leahy JC, deBoisblanc B, Lammi M, Happel K, Lauto P, Self W, Casey J, Semler M, Collins S, Harrell F, Lindsell C, Rice T, Stubblefield W, Gray C, Johnson J, Roth M, Hays M, Torr D, Zakaria A, Schoenfeld D, Thompson T, Hayden D, Ringwood N, Oldmixon C, Ulysse C, Morse R, Muzikansky A, Fitzgerald L, Whitaker S, Lagakos A, Brower R, Reineck L, Aggarwal N, Bienstock K, Freemer M, Maclawiw M, Weinmann G, Morrison L, Gillespie M, Kryscio R, et al. Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial. JAMA. 2020 12 01; 324(21):2165-2176. PMID: 33165621; PMCID: PMC7653542.
    Citations: 151     Fields:    Translation:Humans
  33. Filbin MR, Mehta A, Schneider AM, Kays KR, Guess JR, Gentili M, Fenyves BG, Charland NC, Gonye ALK, Gushterova I, Khanna HK, LaSalle TJ, Lavin-Parsons KM, Lilly BM, Lodenstein CL, Manakongtreecheep K, Margolin JD, McKaig BN, Rojas-Lopez M, Russo BC, Sharma N, Tantivit J, Thomas MF, Gerszten RE, Heimberg GS, Hoover PJ, Lieb DJ, Lin B, Ngo D, Pelka K, Reyes M, Smillie CS, Waghray A, Wood TE, Zajac AS, Jennings LL, Grundberg I, Bhattacharyya RP, Parry BA, Villani AC, Sade-Feldman M, Hacohen N, Goldberg MB. Plasma proteomics reveals tissue-specific cell death and mediators of cell-cell interactions in severe COVID-19 patients. bioRxiv. 2020 Nov 03. PMID: 33173871; PMCID: PMC7654866.
    Citations: 1     
  34. Shrock E, Fujimura E, Kula T, Timms RT, Lee IH, Leng Y, Robinson ML, Sie BM, Li MZ, Chen Y, Logue J, Zuiani A, McCulloch D, Lelis FJN, Henson S, Monaco DR, Travers M, Habibi S, Clarke WA, Caturegli P, Laeyendecker O, Piechocka-Trocha A, Li JZ, Khatri A, Chu HY, Villani AC, Kays K, Goldberg MB, Hacohen N, Filbin MR, Yu XG, Walker BD, Wesemann DR, Larman HB, Lederer JA, Elledge SJ. Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity. Science. 2020 11 27; 370(6520). PMID: 32994364; PMCID: PMC7857405.
    Citations: 204     Fields:    Translation:HumansCells
  35. Sonis JD, Benzer TI, Black L, Filbin MR, Hayes BD, Hibbert KA, Kraus C, Raja AS, Temin E, Vareschi M, White BA, Wilcox SR, Aaronson EL. Utilization of a multidisciplinary emergency department sepsis huddle to reduce time to antibiotics and improve SEP-1 compliance. Am J Emerg Med. 2020 11; 38(11):2400-2404. PMID: 33041123.
    Citations:    Fields:    Translation:Humans
  36. Reyes M, Filbin MR, Bhattacharyya RP, Sonny A, Mehta A, Billman K, Kays KR, Pinilla-Vera M, Benson ME, Cosimi LA, Hung DT, Levy BD, Villani AC, Sade-Feldman M, Baron RM, Goldberg MB, Blainey PC, Hacohen N. Induction of a regulatory myeloid program in bacterial sepsis and severe COVID-19. bioRxiv. 2020 Sep 02. PMID: 32908980; PMCID: PMC7480031.
    Citations:    
  37. Casey JD, Johnson NJ, Semler MW, Collins SP, Aggarwal NR, Brower RG, Chang SY, Eppensteiner J, Filbin M, Gibbs KW, Ginde AA, Gong MN, Harrell F, Hayden DL, Hough CL, Khan A, Leither LM, Moss M, Oldmixon CF, Park PK, Reineck LA, Ringwood NJ, Robinson BRH, Schoenfeld DA, Shapiro NI, Steingrub JS, Torr DK, Weissman A, Lindsell CJ, Rice TW, Thompson BT, Brown SM, Self WH. Rationale and Design of ORCHID: A Randomized Placebo-controlled Clinical Trial of Hydroxychloroquine for Adults Hospitalized with COVID-19. Ann Am Thorac Soc. 2020 09; 17(9):1144-1153. PMID: 32492354; PMCID: PMC7462324.
    Citations: 14     Fields:    Translation:HumansCellsPHPublic Health
  38. Belsky JB, Filbin MR, Rivers EP, Bobbitt KR, Jaehne AK, Wisnik CA, Maciejewski KR, Li F, Morris DC. F-Actin is associated with a worsening qSOFA score and intensive care unit admission in emergency department patients at risk for sepsis. Biomarkers. 2020 Jul; 25(5):391-396. PMID: 32421363.
    Citations: 1     Fields:    Translation:Humans
  39. Reyes M, Filbin MR, Bhattacharyya RP, Billman K, Eisenhaure T, Hung DT, Levy BD, Baron RM, Blainey PC, Goldberg MB, Hacohen N. An immune-cell signature of bacterial sepsis. Nat Med. 2020 03; 26(3):333-340. PMID: 32066974.
    Citations: 74     Fields:    Translation:HumansCells
  40. Filbin MR, Thorsen JE, Zachary TM, Lynch JC, Matsushima M, Belsky JB, Heldt T, Reisner AT. Antibiotic Delays and Feasibility of a 1-Hour-From-Triage Antibiotic Requirement: Analysis of an Emergency Department Sepsis Quality Improvement Database. Ann Emerg Med. 2020 01; 75(1):93-99. PMID: 31561998.
    Citations: 7     Fields:    Translation:Humans
  41. Yende S, Kellum JA, Talisa VB, Peck Palmer OM, Chang CH, Filbin MR, Shapiro NI, Hou PC, Venkat A, LoVecchio F, Hawkins K, Crouser ED, Newman AB, Angus DC. Long-term Host Immune Response Trajectories Among Hospitalized Patients With Sepsis. JAMA Netw Open. 2019 08 02; 2(8):e198686. PMID: 31390038.
    Citations: 37     Fields:    Translation:Humans
  42. Prasad V, Lynch JC, Filbin MR, Reisner AT, Heldt T. Clustering Blood Pressure Trajectories in Septic Shock in the Emergency Department. Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul; 2019:494-497. PMID: 31945945.
    Citations:    Fields:    Translation:Humans
  43. Liao J, Aaronson E, Kim J, Liu X, Snydeman C, Goldfarb I, Black L, Filbin M, Phillips MT, Mort E, Lee J. Association of Hospital Characteristics With Early SEP-1 Performance. Am J Med Qual. 2020 Mar/Apr; 35(2):110-116. PMID: 31226883.
    Citations: 2     Fields:    Translation:Humans
  44. Filbin MR, Heldt T, Reisner AT. The authors reply. Crit Care Med. 2018 12; 46(12):e1222-e1223. PMID: 30444821.
    Citations:    Fields:    Translation:Humans
  45. Massey MJ, Hou PC, Filbin M, Wang H, Ngo L, Huang DT, Aird WC, Novack V, Trzeciak S, Yealy DM, Kellum JA, Angus DC, Shapiro NI. Microcirculatory perfusion disturbances in septic shock: results from the ProCESS trial. Crit Care. 2018 Nov 20; 22(1):308. PMID: 30458880.
    Citations: 22     Fields:    Translation:Humans
  46. Rhee C, Filbin MR, Massaro AF, Bulger AL, McEachern D, Tobin KA, Kitch BT, Thurlo-Walsh B, Kadar A, Koffman A, Pande A, Hamad Y, Warren DK, Jones TM, O'Brien C, Anderson DJ, Wang R, Klompas M. Compliance With the National SEP-1 Quality Measure and Association With Sepsis Outcomes: A Multicenter Retrospective Cohort Study. Crit Care Med. 2018 10; 46(10):1585-1591. PMID: 30015667; PMCID: PMC6138564.
    Citations: 34     Fields:    Translation:Humans
  47. Filbin MR, Lynch J, Gillingham TD, Thorsen JE, Pasakarnis CL, Nepal S, Matsushima M, Rhee C, Heldt T, Reisner AT. Presenting Symptoms Independently Predict Mortality in Septic Shock: Importance of a Previously Unmeasured Confounder. Crit Care Med. 2018 10; 46(10):1592-1599. PMID: 29965833.
    Citations: 34     Fields:    Translation:Humans
  48. Fabian-Jessing BK, Massey MJ, Filbin MR, Hou PC, Wang HE, Kirkegaard H, Yealy DM, Aird WC, Kellum JA, Angus DC, Shapiro NI. In vivo quantification of rolling and adhered leukocytes in human sepsis. Crit Care. 2018 09 30; 22(1):240. PMID: 30268146.
    Citations: 6     Fields:    Translation:HumansCells
  49. Filbin MR, Thorsen JE, Lynch J, Gillingham TD, Pasakarnis CL, Capp R, Shapiro NI, Mooncai T, Hou PC, Heldt T, Reisner AT. Challenges and Opportunities for Emergency Department Sepsis Screening at Triage. Sci Rep. 2018 07 23; 8(1):11059. PMID: 30038408.
    Citations: 7     Fields:    Translation:Humans
  50. Huang DT, Yealy DM, Filbin MR, Brown AM, Chang CH, Doi Y, Donnino MW, Fine J, Fine MJ, Fischer MA, Holst JM, Hou PC, Kellum JA, Khan F, Kurz MC, Lotfipour S, LoVecchio F, Peck-Palmer OM, Pike F, Prunty H, Sherwin RL, Southerland L, Terndrup T, Weissfeld LA, Yabes J, Angus DC. Procalcitonin-Guided Use of Antibiotics for Lower Respiratory Tract Infection. N Engl J Med. 2018 Jul 19; 379(3):236-249. PMID: 29781385; PMCID: PMC6197800.
    Citations: 92     Fields:    Translation:Humans
  51. Shapiro NI, Self WH, Rosen J, Sharp SC, Filbin MR, Hou PC, Parekh AD, Kurz MC, Sambursky R. A prospective, multi-centre US clinical trial to determine accuracy of FebriDx point-of-care testing for acute upper respiratory infections with and without a confirmed fever. Ann Med. 2018 08; 50(5):420-429. PMID: 29775092.
    Citations: 17     Fields:    Translation:Humans
  52. Belsky JB, Rivers EP, Filbin MR, Lee PJ, Morris DC. Thymosin beta 4 regulation of actin in sepsis. Expert Opin Biol Ther. 2018 07; 18(sup1):193-197. PMID: 29508629; PMCID: PMC6556887.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  53. Self WH, Rosen J, Sharp SC, Filbin MR, Hou PC, Parekh AD, Kurz MC, Shapiro NI. Diagnostic Accuracy of FebriDx: A Rapid Test to Detect Immune Responses to Viral and Bacterial Upper Respiratory Infections. J Clin Med. 2017 Oct 07; 6(10). PMID: 28991170; PMCID: PMC5664009.
    Citations: 17     
  54. Prasad V, Lynch JC, Pasakarnis CL, Thorsen JE, Filbin MR, Reisner AT, Heldt T. Classification models to predict vasopressor administration for septic shock in the emergency department. Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul; 2017:2650-2653. PMID: 29060444.
    Citations:    Fields:    Translation:Humans
  55. Hou PC, Filbin MR, Wang H, Ngo L, Huang DT, Aird WC, Yealy DM, Angus DC, Kellum JA, Shapiro NI. Endothelial Permeability and Hemostasis in Septic Shock: Results From the ProCESS Trial. Chest. 2017 07; 152(1):22-31. PMID: 28109962; PMCID: PMC5577354.
    Citations: 38     Fields:    Translation:HumansCells
  56. McCluskey SM, Schuetz P, Abers MS, Bearnot B, Morales ME, Hoffman D, Patel S, Rosario L, Chiappa V, Parry BA, Callahan RT, Bond SA, Lewandrowski K, Binder W, Filbin MR, Vyas JM, Mansour MK. Serial Procalcitonin as a Predictor of Bacteremia and Need for Intensive Care Unit Care in Adults With Pneumonia, Including Those With Highest Severity: A Prospective Cohort Study. Open Forum Infect Dis. 2017; 4(1):ofw238. PMID: 28480236; PMCID: PMC5414101.
    Citations: 3     
  57. Aaronson EL, Filbin MR, Brown DF, Tobin K, Mort EA. New Mandated Centers for Medicare and Medicaid Services Requirements for Sepsis Reporting: Caution from the Field. J Emerg Med. 2017 Jan; 52(1):109-116. PMID: 27720289.
    Citations: 10     Fields:    Translation:Humans
  58. Pallin DJ, Bry L, Dwyer RC, Lipworth AD, Leung DY, Camargo CA, Kupper TS, Filbin MR, Murphy GF. Toward an Objective Diagnostic Test for Bacterial Cellulitis. PLoS One. 2016; 11(9):e0162947. PMID: 27656884.
    Citations: 6     Fields:    
  59. Hou PC, Filbin MR, Napoli A, Feldman J, Pang PS, Sankoff J, Lo BM, Dickey-White H, Birkhahn RH, Shapiro NI. Cardiac Output Monitoring Managing Intravenous Therapy (COMMIT) to Treat Emergency Department Patients with Sepsis. Shock. 2016 08; 46(2):132-8. PMID: 26925867.
    Citations: 5     Fields:    Translation:Humans
  60. Fuentes E, Shields JF, Chirumamilla N, Martinez M, Kaafarani H, Yeh DD, White B, Filbin M, DePesa C, Velmahos G, Lee J. "One-way-street" streamlined admission of critically ill trauma patients reduces emergency department length of stay. Intern Emerg Med. 2017 Oct; 12(7):1019-1024. PMID: 27473424.
    Citations: 4     Fields:    Translation:Humans
  61. Goto T, Yoshida K, Tsugawa Y, Filbin MR, Camargo CA, Hasegawa K. Mortality trends in U.S. adults with septic shock, 2005-2011: a serial cross-sectional analysis of nationally-representative data. BMC Infect Dis. 2016 06 14; 16:294. PMID: 27301657; PMCID: PMC4908776.
    Citations: 3     Fields:    Translation:Humans
  62. Belsky JB, Morris DC, Bouchebl R, Filbin MR, Bobbitt KR, Jaehne AK, Rivers EP. Plasma levels of F-actin and F:G-actin ratio as potential new biomarkers in patients with septic shock. Biomarkers. 2016; 21(2):180-5. PMID: 26754286.
    Citations: 4     Fields:    Translation:Humans
  63. Yealy DM, Kellum JA, Huang DT, Barnato AE, Weissfeld LA, Pike F, Terndrup T, Wang HE, Hou PC, LoVecchio F, Filbin MR, Shapiro NI, Angus DC. A randomized trial of protocol-based care for early septic shock. N Engl J Med. 2014 May 01; 370(18):1683-93. PMID: 24635773; PMCID: PMC4101700.
    Citations: 747     Fields:    Translation:Humans
  64. Filbin MR, Arias SA, Camargo CA, Barche A, Pallin DJ. Sepsis visits and antibiotic utilization in U.S. emergency departments*. Crit Care Med. 2014 Mar; 42(3):528-35. PMID: 24201179.
    Citations: 20     Fields:    Translation:Humans
  65. Filbin MR, Hou PC, Massey M, Barche A, Kao E, Bracey A, Skibsted S, Chang Y, Shapiro NI. The microcirculation is preserved in emergency department low-acuity sepsis patients without hypotension. Acad Emerg Med. 2014 Feb; 21(2):154-62. PMID: 24673671.
    Citations: 5     Fields:    Translation:Humans
  66. Pallin DJ, Binder WD, Allen MB, Lederman M, Parmar S, Filbin MR, Hooper DC, Camargo CA. Clinical trial: comparative effectiveness of cephalexin plus trimethoprim-sulfamethoxazole versus cephalexin alone for treatment of uncomplicated cellulitis: a randomized controlled trial. Clin Infect Dis. 2013 Jun; 56(12):1754-62. PMID: 23457080.
    Citations: 31     Fields:    Translation:HumansCells
  67. Filbin MR, Ring DC, Wessels MR, Avery LL, Kradin RL. Case records of the Massachusetts General Hospital. Case 2-2009. A 25-year-old man with pain and swelling of the right hand and hypotension. N Engl J Med. 2009 Jan 15; 360(3):281-90. PMID: 19144944.
    Citations: 2     Fields:    Translation:HumansCells
  68. Varon J, Fromm RE, Chanin K, Filbin M, Vutpakdi K. Critical illness at mass gatherings is uncommon. J Emerg Med. 2003 Nov; 25(4):409-13. PMID: 14654182.
    Citations: 1     Fields:    Translation:Humans
  69. Sivilotti ML, Filbin MR, Murray HE, Slasor P, Walls RM. Does the sedative agent facilitate emergency rapid sequence intubation? Acad Emerg Med. 2003 Jun; 10(6):612-20. PMID: 12782521.
    Citations: 10     Fields:    Translation:HumansCTClinical Trials
  70. Filbin MR, Lee L, Shaffer B. Blueprints: Pathophysiology II - Pulmonary, Gastrointestinal, and Rheumatology: Notes & Cases. 2003.
  71. Sivilotti MLA, Filbin MR, Slasor P, Walls RM. Sedative agents for emergency rapid sequence intubation: Selection and outcome. Annals of Emergency Medicine. 2003.
  72. Bair AE, Filbin MR, Kulkarni RG, Walls RM. The failed intubation attempt in the emergency department: analysis of prevalence, rescue techniques, and personnel. J Emerg Med. 2002 Aug; 23(2):131-40. PMID: 12359280.
    Citations: 34     Fields:    Translation:Humans
  73. Filbin MR, Tsien Cl, Caughey AB. Blueprints: Clinical Cases in emergency medicine. 2002.
  74. Bair AE, Filbin MR, Kulkarni RG, Walls RM. Failed intubation in the emergency department: Analysis of prevalence, rescue techniques and personnel. Journal of Emergency Medicine. 2002.
  75. Filbin MR, Brown DFM. Unstable angina and non ST elevation MI: IIB or not IIB?. Journal of Critical Illness. 2002; 17:52-65.
  76. Filbin MR, Brown DF, Nadel ES. Hyperglycemic Hyperosmotic Nonketotic Coma. Journal of Emergency Medicine. 2001; 20(3):285-290.
  77. Filbin MR, Brown DF, Nadel ES. Hyperglycemic hyperosmolar nonketotic coma. J Emerg Med. 2001 Apr; 20(3):285-90. PMID: 11267819.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  78. Gutman MB, Kulkarni RG, Weissman A, Sagarin M, Filbin MR, Walls RM. Midazolam causes hypotension and etomidate does not in emergency endotracheal intubation. Annals of Emergency Medicine. 2001.
  79. Filbin MR, Mylonakis EE, Callegari L, Legome E. Babesiosis. J Emerg Med. 2001 Jan; 20(1):21-4. PMID: 11165832.
    Citations: 4     Fields:    Translation:Humans
  80. Sivilotti MLA, Filbin MR, Slasor P, Walls RM. Factors involved in the selection of induction agents during emergency rapid sequence intubation. Annals of Emergency Medicine. 2000; 34.
  81. Filbin MR, Kulkarni RG, Wong E, et al. Difficult intubation predictor scale: Evaluation of inter-observer reliability for a new clinical instrument to predict difficult intubations. Academic Emergency Medicine. 2000; 7(5):527.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.