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David Wypij, Ph.D.

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Overview
David Wypij 's main activities and interests focus on active collaboration in pediatric clinical research studies and in biostatistical education and administration. Recent work has implemented novel methods in longitudinal data analysis, semiparametric regression, classification and regression trees, mobility measures based on Markov chains, and vaccine efficacy modeling in medical and public health studies.
In work at Children's Hospital Boston, Dr. Wypij collaborates on several randomized clinical trials and follow-up studies that compare the incidence of brain injury after operative strategies in infant heart surgery. The focus has been on the neurodevelopment of subjects as measured through psychological and psychiatric testing, neurologic evaluation, and brain assessment by magnetic resonance imaging, postoperatively through 18 years of age. He directs the Data Coordinating Center for the RESTORE study, assessing a new sedation management algorithm in pediatric patients with acute lung injury in a group-randomized 21-center study with over 2700 patients, and for the TECS study, assessing the efficacy of strict glycemic control in reducing infection in postoperative pediatric cardiac surgery patients in a randomized 2-center study with over 900 patients. Dr. Wypij also collaborates on longitudinal studies of associations between the sexual orientation of adolescents and young adults and health risk behaviors such as alcohol and drug use, eating disorders, and stress and self-esteem. He has collaborated on many other studies with investigators from the Departments of Adolescent Medicine, Cardiology, Cardiac Surgery, Neurology, Psychiatry, and Radiology at Children's Hospital.
Dr. Wypij also collaborates with the Severe Malaria in African Children (SMAC) clinical research network, involving investigators in the United States, Africa, and Europe. Recent work has focused on the association of acid/base balance and pigment to malaria mortality in a cohort of over 26,000 hospital admissions in five African countries. Current focus is on the use of classification trees, generalized additive models, and frailty survival models to predict mortality among African malaria patients, as well as assessing the clinical significance of eye examinations in predicting "true" cerebral malaria and to brain histology (in fatal cases).
As Director of Graduate Studies, Dr. Wypij oversees admissions and recruitment, funding, student advising, orientation, teaching and research assistantships, and related student administration activities in the Department of Biostatistics at HSPH. He is an award-winning teacher at HSPH, and he has also taught short courses in biostatistics and clinical research methods in Brazil, Gabon, Greece, Italy, Portugal, and at Children's Hospital Boston.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HD096901 (AGUS, MICHAEL SD) Jul 1, 2019 - Jun 30, 2024
    NIH
    SHIPSS: Stress Hydrocortisone In Pediatric Septic Shock
    Role: Co-Principal Investigator
  2. U24HL141723 (WYPIJ, DAVID) Jun 15, 2018 - Jul 31, 2024
    NIH
    2/2 PROSpect: Prone and Oscillation Pediatric Clinical Trial (DCC)
    Role: Principal Investigator
  3. U01HL108028 (WYPIJ, DAVID) Jul 1, 2011 - Jun 30, 2018
    NIH
    HALF-PINT: Heart And Lung Failure - Pediatric INsulin Titration trial - DCC
    Role: Principal Investigator
  4. U01HL086649 (WYPIJ, DAVID) Apr 1, 2008 - Mar 31, 2014
    NIH
    Sedation Management in Pediatric Patients with Acute Respiratory Failure (DCC)
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Yim G, Roberts A, Ascherio A, Wypij D, Kioumourtzoglou MA, Weisskopf AMG. Smoking During Pregnancy and Risk of Attention-deficit/Hyperactivity Disorder in the Third Generation. Epidemiology. 2022 May 01; 33(3):431-440. PMID: 35213510.
    Citations:    Fields:    
  2. Majeed A, Rofeberg V, Bellinger DC, Wypij D, Newburger JW. Machine Learning to Predict Executive Function in Adolescents with Repaired d-TGA, TOF, and Fontan Palliation. J Pediatr. 2022 Mar 18. PMID: 35314155.
    Citations:    Fields:    
  3. Watson RS, Beers SR, Asaro LA, Burns C, Koh MJ, Perry MA, Angus DC, Wypij D, Curley MAQ. Association of Acute Respiratory Failure in Early Childhood With Long-term Neurocognitive Outcomes. JAMA. 2022 03 01; 327(9):836-845. PMID: 35230393.
    Citations:    Fields:    
  4. Sadhwani A, Wypij D, Rofeberg V, Gholipour A, Mittleman M, Rohde J, Velasco-Annis C, Calderon J, Friedman KG, Tworetzky W, Grant PE, Soul JS, Warfield SK, Newburger JW, Ortinau CM, Rollins CK. Fetal Brain Volume Predicts Neurodevelopment in Congenital Heart Disease. Circulation. 2022 Apr 12; 145(15):1108-1119. PMID: 35143287.
    Citations:    Fields:    
  5. Kachmar AG, Watson RS, Wypij D, Perry MA, Curley MAQ. Association of Socioeconomic Status With Postdischarge Pediatric Resource Use and Quality of Life. Crit Care Med. 2022 02 01; 50(2):e117-e128. PMID: 34495879.
    Citations:    Fields:    Translation:Humans
  6. Yim G, Roberts A, Wypij D, Kioumourtzoglou MA, Weisskopf MG. Grandmothers' endocrine disruption during pregnancy, low birth weight, and preterm birth in third generation. Int J Epidemiol. 2022 01 06; 50(6):1886-1896. PMID: 34999879.
    Citations:    Fields:    
  7. Rudolph MW, Kneyber MCJ, Asaro LA, Cheifetz IM, Wypij D, Curley MAQ. Early Neuromuscular Blockade in Moderate-to-Severe Pediatric Acute Respiratory Distress Syndrome. Crit Care Med. 2022 Jan 06. PMID: 35029869.
    Citations:    Fields:    
  8. Butler SC, Sadhwani A, Rofeberg V, Cassidy AR, Singer J, Calderon J, Wypij D, Newburger JW, Rollins CK. Neurological features in infants with congenital heart disease. Dev Med Child Neurol. 2021 Dec 18. PMID: 34921736.
    Citations:    Fields:    
  9. Kachmar AG, Wypij D, Perry MA, Curley MAQ. Income-driven socioeconomic status and presenting illness severity in children with acute respiratory failure. Res Nurs Health. 2021 12; 44(6):920-930. PMID: 34505720.
    Citations:    Fields:    Translation:Humans
  10. Morton SU, Maleyeff L, Wypij D, Yun HJ, Rollins CK, Watson CG, Newburger JW, Bellinger DC, Roberts AE, Rivkin MJ, Grant PE, Im K. Abnormal Right-Hemispheric Sulcal Patterns Correlate with Executive Function in Adolescents with Tetralogy of Fallot. Cereb Cortex. 2021 08 26; 31(10):4670-4680. PMID: 34009260.
    Citations: 1     Fields:    
  11. Perry MA, Dawkins-Henry OS, Awojoodu RE, Blumenthal J, Asaro LA, Wypij D, Kudchadkar SR, Zuppa AF, Curley MAQ. Study protocol for a two-center test of a nurse-implemented chronotherapeutic restoring bundle in critically ill children: RESTORE Resilience (R2). Contemp Clin Trials Commun. 2021 Sep; 23:100840. PMID: 34466711.
    Citations:    
  12. Yim G, Roberts A, Ascherio A, Wypij D, Kioumourtzoglou MA, Weisskopf MG. Association Between Periconceptional Weight of Maternal Grandmothers and Attention-Deficit/Hyperactivity Disorder in Grandchildren. JAMA Netw Open. 2021 07 01; 4(7):e2118824. PMID: 34323981.
    Citations:    Fields:    Translation:HumansCells
  13. Kopp W, Gedeit RG, Asaro LA, McLaughlin GE, Wypij D, Curley MAQ. The Impact of Preintubation Noninvasive Ventilation on Outcomes in Pediatric Acute Respiratory Distress Syndrome. Crit Care Med. 2021 05 01; 49(5):816-827. PMID: 33590999.
    Citations: 1     Fields:    Translation:Humans
  14. Yim G, Roberts A, Wypij D, Kioumourtzoglou MA, Weisskopf MG. Grandmothers' endocrine disruption during pregnancy, low birth weight, and preterm birth in third generation. Int J Epidemiol. 2021 Apr 05. PMID: 33822959.
    Citations:    Fields:    
  15. Lebet RM, Hasbani NR, Sisko MT, Agus MSD, Nadkarni VM, Wypij D, Curley MAQ. Nurses' Perceptions of Workload Burden in Pediatric Critical Care. Am J Crit Care. 2021 01 01; 30(1):27-35. PMID: 33385203.
    Citations: 2     Fields:    Translation:Humans
  16. Natale JE, Asaro LA, Joseph JG, Ulysse C, Ascenzi J, Bowens C, Wypij D, Curley MAQ. Association of Race and Ethnicity with Sedation Management in Pediatric Intensive Care. Ann Am Thorac Soc. 2021 01; 18(1):93-102. PMID: 32776853.
    Citations: 1     Fields:    Translation:Humans
  17. Soul JS, Bergin AM, Stopp C, Hayes B, Singh A, Fortuno CR, O'Reilly D, Krishnamoorthy K, Jensen FE, Rofeberg V, Dong M, Vinks AA, Wypij D, Staley KJ. A Pilot Randomized, Controlled, Double-Blind Trial of Bumetanide to Treat Neonatal Seizures. Ann Neurol. 2021 02; 89(2):327-340. PMID: 33201535.
    Citations: 8     Fields:    Translation:Humans
  18. Rollins CK, Ortinau CM, Stopp C, Friedman KG, Tworetzky W, Gagoski B, Velasco-Annis C, Afacan O, Vasung L, Beaute JI, Rofeberg V, Estroff JA, Grant PE, Soul JS, Yang E, Wypij D, Gholipour A, Warfield SK, Newburger JW. Regional Brain Growth Trajectories in Fetuses with Congenital Heart Disease. Ann Neurol. 2021 01; 89(1):143-157. PMID: 33084086.
    Citations: 4     Fields:    Translation:Humans
  19. Miller TA, Sadhwani A, Sanz J, Sood E, Ilardi D, Newburger JW, Goldberg CS, Wypij D, Gaynor JW, Marino BS. Variations in practice in cardiac neurodevelopmental follow-up programs. Cardiol Young. 2020 Nov; 30(11):1603-1608. PMID: 33094709.
    Citations: 3     Fields:    Translation:Humans
  20. Creedon JK, Vargas S, Asaro LA, Wypij D, Paul R, Melendez E. Timing of Antibiotic Administration in Pediatric Sepsis. Pediatr Emerg Care. 2020 Oct; 36(10):464-467. PMID: 30489491.
    Citations: 7     Fields:    Translation:Humans
  21. Stellar JJ, Hasbani NR, Kulik LA, Shelley SS, Quigley S, Wypij D, Curley MAQ. Medical Device-Related Pressure Injuries in Infants and Children. J Wound Ostomy Continence Nurs. 2020 Sep/Oct; 47(5):459-469. PMID: 32970031.
    Citations:    Fields:    Translation:Humans
  22. Calderon J, Wypij D, Rofeberg V, Stopp C, Roseman A, Albers D, Newburger JW, Bellinger DC. Randomized Controlled Trial of Working Memory Intervention in Congenital Heart Disease. J Pediatr. 2020 12; 227:191-198.e3. PMID: 32827526.
    Citations: 3     Fields:    Translation:Humans
  23. Jaimes C, Rofeberg V, Stopp C, Ortinau CM, Gholipour A, Friedman KG, Tworetzky W, Estroff J, Newburger JW, Wypij D, Warfield SK, Yang E, Rollins CK. Association of Isolated Congenital Heart Disease with Fetal Brain Maturation. AJNR Am J Neuroradiol. 2020 08; 41(8):1525-1531. PMID: 32646947.
    Citations: 4     Fields:    Translation:Humans
  24. Morton SU, Maleyeff L, Wypij D, Yun HJ, Newburger JW, Bellinger DC, Roberts AE, Rivkin MJ, Seidman JG, Seidman CE, Grant PE, Im K. Abnormal Left-Hemispheric Sulcal Patterns Correlate with Neurodevelopmental Outcomes in Subjects with Single Ventricular Congenital Heart Disease. Cereb Cortex. 2020 03 21; 30(2):476-487. PMID: 31216004.
    Citations: 7     Fields:    Translation:Humans
  25. Srinivasan V, Hasbani NR, Mehta NM, Irving SY, Kandil SB, Allen HC, Typpo KV, Cvijanovich NZ, Faustino EVS, Wypij D, Agus MSD, Nadkarni VM. Early Enteral Nutrition Is Associated With Improved Clinical Outcomes in Critically Ill Children: A Secondary Analysis of Nutrition Support in the Heart and Lung Failure-Pediatric Insulin Titration Trial. Pediatr Crit Care Med. 2020 03; 21(3):213-221. PMID: 31577692.
    Citations: 5     Fields:    Translation:Humans
  26. Biagas KV, Hinton VJ, Hasbani NR, Luckett PM, Wypij D, Nadkarni VM, Agus MSD. Long-Term Neurobehavioral and Quality of Life Outcomes of Critically Ill Children after Glycemic Control. J Pediatr. 2020 03; 218:57-63.e5. PMID: 31910992.
    Citations: 1     Fields:    Translation:Humans
  27. Goldstone AB, Baiocchi M, Wypij D, Stopp C, Andropoulos DB, Atallah J, Atz AM, Beca J, Donofrio MT, Duncan K, Ghanayem NS, Goldberg CS, Hövels-Gürich H, Ichida F, Jacobs JP, Justo R, Latal B, Li JS, Mahle WT, McQuillen PS, Menon SC, Pike NA, Pizarro C, Shekerdemian LS, Synnes A, Williams IA, Bellinger DC, Newburger J, Gaynor JW. The Bayley-III scale may underestimate neurodevelopmental disability after cardiac surgery in infants. Eur J Cardiothorac Surg. 2020 01 01; 57(1):63-71. PMID: 31006006.
    Citations:    Fields:    Translation:Humans
  28. Marsillio LE, Asaro LA, Srinivasan V, Wypij D, Sorce LR, Agus MSD, Nadkarni VM. Outcomes Associated With Multiple Organ Dysfunction Syndrome in Critically Ill Children With Hyperglycemia. Pediatr Crit Care Med. 2019 12; 20(12):1147-1156. PMID: 31688812.
    Citations: 1     Fields:    Translation:Humans
  29. Kulik LA, Hasbani NR, Stellar JJ, Quigley SM, Shelley SS, Wypij D, Curley MAQ. Hospital-Acquired Pressure Injuries in Children With Congenital Heart Disease: Prevalence and Associated Factors. Pediatr Crit Care Med. 2019 11; 20(11):1048-1056. PMID: 31385861.
    Citations: 3     Fields:    Translation:Humans
  30. Watson RS, Asaro LA, Hutchins L, Bysani GK, Killien EY, Angus DC, Wypij D, Curley MAQ. Risk Factors for Functional Decline and Impaired Quality of Life after Pediatric Respiratory Failure. Am J Respir Crit Care Med. 2019 10 01; 200(7):900-909. PMID: 31034245.
    Citations: 16     Fields:    Translation:Humans
  31. Sadhwani A, Cheng H, Stopp C, Rollins CK, Jolley MA, Dunbar-Masterson C, Wypij D, Newburger J, Ware J, Thiagarajan RR. Early Neurodevelopmental Outcomes in Children Supported with ECMO for Cardiac Indications. Pediatr Cardiol. 2019 Jun; 40(5):1072-1083. PMID: 31079193.
    Citations: 6     Fields:    Translation:Humans
  32. Faustino EVS, Hirshberg EL, Asaro LA, Biagas KV, Pinto N, Srinivasan V, Bagdure DN, Steil GM, Coughlin-Wells K, Wypij D, Nadkarni VM, Agus MSD, Mourani PM, Chima R, Thomas NJ, Li S, Pinto A, Newth C, Hassinger A, Bysani K, Rehder KJ, Kandil S, Wintergerst K, Schwarz A, Marsillio L, Cvijanovich N, Pham N, Quasney M, Flori H, Federman M, Nett S, Viteri S, Schneider J, Medar S, Sapru A, McQuillen P, Babbitt C, Lin JC, Jouvet P, Yanay O, Allen C. Short-Term Adverse Outcomes Associated With Hypoglycemia in Critically Ill Children. Crit Care Med. 2019 05; 47(5):706-714. PMID: 30789401.
    Citations: 4     Fields:    Translation:Humans
  33. LeBrun DG, Tran T, Wypij D, Kocher MS. How Often Do Orthopaedic Matched Case-Control Studies Use Matched Methods? A Review of Methodological Quality. Clin Orthop Relat Res. 2019 03; 477(3):655-662. PMID: 30614911.
    Citations: 10     Fields:    Translation:Humans
  34. Calderon J, Bellinger DC, Hartigan C, Lord A, Stopp C, Wypij D, Newburger JW. Improving neurodevelopmental outcomes in children with congenital heart disease: protocol for a randomised controlled trial of working memory training. BMJ Open. 2019 02 19; 9(2):e023304. PMID: 30782877.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  35. Curley MAQ, Gedeit RG, Dodson BL, Amling JK, Soetenga DJ, Corriveau CO, Asaro LA, Wypij D. Correction to: Methods in the design and implementation of the Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) clinical trial. Trials. 2019 01 07; 20(1):17. PMID: 30616620.
    Citations: 1     Fields:    
  36. LeBrun DG, Tran T, Wypij D, Kocher MS. Statistical Analysis of Dependent Observations in the Orthopaedic Sports Literature. Orthop J Sports Med. 2019 Jan; 7(1):2325967118818410. PMID: 30637265.
    Citations: 1     
  37. Zaidi AH, Newburger JW, Wypij D, Stopp C, Watson CG, Friedman KG, Rivkin MJ, Rollins CK. Ascending Aorta Size at Birth Predicts White Matter Microstructure in Adolescents Who Underwent Fontan Palliation. J Am Heart Assoc. 2018 12 18; 7(24):e010395. PMID: 30561261.
    Citations: 4     Fields:    Translation:Humans
  38. Curley MAQ, Gedeit RG, Dodson BL, Amling JK, Soetenga DJ, Corriveau CO, Asario LA, Wypij D. Methods in the design and implementation of the Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) clinical trial. Trials. 2018 12 17; 19(1):687. PMID: 30558653.
    Citations: 5     Fields:    Translation:Humans
  39. Butler SC, Sadhwani A, Stopp C, Singer J, Wypij D, Dunbar-Masterson C, Ware J, Newburger JW. Neurodevelopmental assessment of infants with congenital heart disease in the early postoperative period. Congenit Heart Dis. 2019 Mar; 14(2):236-245. PMID: 30324749.
    Citations: 6     Fields:    Translation:Humans
  40. Robson VK, Stopp C, Wypij D, Dunbar-Masterson C, Bellinger DC, DeMaso DR, Rappaport LA, Newburger JW. Longitudinal Associations between Neurodevelopment and Psychosocial Health Status in Patients with Repaired D-Transposition of the Great Arteries. J Pediatr. 2019 01; 204:38-45.e1. PMID: 30274922.
    Citations: 4     Fields:    Translation:Humans
  41. Barbaro RP, Thiagarajan RR, Wypij D, Curley MAQ. Reply to Rambaud et al.: Do We Really Doubt Extracorporeal Membrane Oxygenation Efficacy in Pediatric Acute Respiratory Distress Syndrome? Am J Respir Crit Care Med. 2018 08 01; 198(3):409-410. PMID: 29617573.
    Citations: 2     Fields:    Translation:Humans
  42. Curley MAQ, Watson RS, Cassidy AM, Burns C, Delinger RL, Angus DC, Asaro LA, Wypij D, Beers SR. Design and rationale of the "Sedation strategy and cognitive outcome after critical illness in early childhood" study. Contemp Clin Trials. 2018 09; 72:8-15. PMID: 30017814.
    Citations: 4     Fields:    Translation:Humans
  43. Watson CG, Stopp C, Wypij D, Bellinger DC, Newburger JW, Rivkin MJ. Altered White Matter Microstructure Correlates with IQ and Processing Speed in Children and Adolescents Post-Fontan. J Pediatr. 2018 09; 200:140-149.e4. PMID: 29934026.
    Citations: 11     Fields:    Translation:Humans
  44. Watson RS, Asaro LA, Hertzog JH, Sorce LR, Kachmar AG, Dervan LA, Angus DC, Wypij D, Curley MAQ. Long-Term Outcomes after Protocolized Sedation versus Usual Care in Ventilated Pediatric Patients. Am J Respir Crit Care Med. 2018 06 01; 197(11):1457-1467. PMID: 29313710.
    Citations: 25     Fields:    Translation:Humans
  45. Barbaro RP, Xu Y, Borasino S, Truemper EJ, Watson RS, Thiagarajan RR, Wypij D, Curley MAQ. Does Extracorporeal Membrane Oxygenation Improve Survival in Pediatric Acute Respiratory Failure? Am J Respir Crit Care Med. 2018 05 01; 197(9):1177-1186. PMID: 29373797.
    Citations: 17     Fields:    Translation:Humans
  46. Ross CE, Asaro LA, Wypij D, Holland CC, Donnino MW, Kleinman ME. Physiologic response to pre-arrest bolus dilute epinephrine in the pediatric intensive care unit. Resuscitation. 2018 05; 126:137-142. PMID: 29526678.
    Citations: 3     Fields:    Translation:Humans
  47. Merritt C, Menon K, Agus MSD, Choong K, McNally D, O'Hearn K, Watson RS, Wong HR, Duffett M, Wypij D, Zimmerman JJ. Beyond Survival: Pediatric Critical Care Interventional Trial Outcome Measure Preferences of Families and Healthcare Professionals. Pediatr Crit Care Med. 2018 02; 19(2):e105-e111. PMID: 29394234.
    Citations: 19     Fields:    Translation:Humans
  48. Curley MAQ, Hasbani NR, Quigley SM, Stellar JJ, Pasek TA, Shelley SS, Kulik LA, Chamblee TB, Dilloway MA, Caillouette CN, McCabe MA, Wypij D. Predicting Pressure Injury Risk in Pediatric Patients: The Braden QD Scale. J Pediatr. 2018 01; 192:189-195.e2. PMID: 29246340.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  49. Schneider JB, Sweberg T, Asaro LA, Kirby A, Wypij D, Thiagarajan RR, Curley MAQ. Sedation Management in Children Supported on Extracorporeal Membrane Oxygenation for Acute Respiratory Failure. Crit Care Med. 2017 10; 45(10):e1001-e1010. PMID: 28614197.
    Citations: 4     Fields:    Translation:Humans
  50. Lebet R, Hayakawa J, Chamblee TB, Tala JA, Singh N, Wypij D, Curley MAQ. Maintaining Interrater Agreement of Core Assessment Instruments in a Multisite Randomized Controlled Clinical Trial: The Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) Trial. Nurs Res. 2017 Jul/Aug; 66(4):323-329. PMID: 28654569.
    Citations: 2     Fields:    Translation:Humans
  51. Blinder JJ, Asaro LA, Wypij D, Selewski DT, Agus MSD, Gaies M, Ferguson MA. Acute Kidney Injury After Pediatric Cardiac Surgery: A Secondary Analysis of the Safe Pediatric Euglycemia After Cardiac Surgery Trial. Pediatr Crit Care Med. 2017 Jul; 18(7):638-646. PMID: 28492399.
    Citations: 19     Fields:    Translation:Humans
  52. Agus MSD, Wypij D, Nadkarni, VM. Tight Glycemic Control in Critically Ill Children. N Engl J Med. 2017 06 08; 376(23):e48. PMID: 28591530.
    Citations: 3     Fields:    Translation:Humans
  53. Best KM, Wypij D, Asaro LA, Curley MAQ. The authors reply. Crit Care Med. 2017 06; 45(6):e623-e624. PMID: 28509749.
    Citations:    Fields:    Translation:Humans
  54. Weiss SL, Asaro LA, Flori HR, Allen GL, Wypij D, Curley MA. Multiple Organ Dysfunction in Children Mechanically Ventilated for Acute Respiratory Failure. Pediatr Crit Care Med. 2017 Apr; 18(4):319-329. PMID: 28212163.
    Citations: 11     Fields:    Translation:Humans
  55. Ferradal SL, Yuki K, Vyas R, Ha CG, Yi F, Stopp C, Wypij D, Cheng HH, Newburger JW, Kaza AK, Franceschini MA, Kussman BD, Grant PE. Non-invasive Assessment of Cerebral Blood Flow and Oxygen Metabolism in Neonates during Hypothermic Cardiopulmonary Bypass: Feasibility and Clinical Implications. Sci Rep. 2017 03 09; 7:44117. PMID: 28276534.
    Citations: 14     Fields:    Translation:HumansCTClinical Trials
  56. Natale JE, Lebet R, Joseph JG, Ulysse C, Ascenzi J, Wypij D, Curley MAQ. Racial and Ethnic Disparities in Parental Refusal of Consent in a Large, Multisite Pediatric Critical Care Clinical Trial. J Pediatr. 2017 05; 184:204-208.e1. PMID: 28410087.
    Citations: 8     Fields:    Translation:Humans
  57. Faustino EV, Gedeit RG, Schwarz A, Asaro LA, Wypij D, Curley MA. The authors reply. Crit Care Med. 2017 03; 45(3):e333-e334. PMID: 28212236.
    Citations:    Fields:    
  58. Menon K, McNally JD, Zimmerman JJ, Agus MS, O'Hearn K, Watson RS, Wong HR, Duffett M, Wypij D, Choong K. Primary Outcome Measures in Pediatric Septic Shock Trials: A Systematic Review. Pediatr Crit Care Med. 2017 Mar; 18(3):e146-e154. PMID: 28099233.
    Citations: 9     Fields:    Translation:Humans
  59. Watson CG, Stopp C, Wypij D, Newburger JW, Rivkin MJ. Reduced cortical volume and thickness and their relationship to medical and operative features in post-Fontan children and adolescents. Pediatr Res. 2017 Jun; 81(6):881-890. PMID: 28157834.
    Citations: 9     Fields:    Translation:Humans
  60. DeMaso DR, Calderon J, Taylor GA, Holland JE, Stopp C, White MT, Bellinger DC, Rivkin MJ, Wypij D, Newburger JW. Psychiatric Disorders in Adolescents With Single Ventricle Congenital Heart Disease. Pediatrics. 2017 Mar; 139(3). PMID: 28148729.
    Citations: 28     Fields:    Translation:Humans
  61. Agus MS, Wypij D, Hirshberg EL, Srinivasan V, Faustino EV, Luckett PM, Alexander JL, Asaro LA, Curley MA, Steil GM, Nadkarni VM. Tight Glycemic Control in Critically Ill Children. N Engl J Med. 2017 02 23; 376(8):729-741. PMID: 28118549.
    Citations: 49     Fields:    Translation:Humans
  62. Best KM, Wypij D, Asaro LA, Curley MA. Patient, Process, and System Predictors of Iatrogenic Withdrawal Syndrome in Critically Ill Children. Crit Care Med. 2017 Jan; 45(1):e7-e15. PMID: 27513532.
    Citations: 13     Fields:    Translation:Humans
  63. Faustino EV, Gedeit R, Schwarz AJ, Asaro LA, Wypij D, Curley MA. Accuracy of an Extubation Readiness Test in Predicting Successful Extubation in Children With Acute Respiratory Failure From Lower Respiratory Tract Disease. Crit Care Med. 2017 Jan; 45(1):94-102. PMID: 27632676.
    Citations: 9     Fields:    Translation:Humans
  64. Agus MS, Hirshberg E, Srinivasan V, Faustino EV, Luckett PM, Curley MA, Alexander J, Asaro LA, Coughlin-Wells K, Duva D, French J, Hasbani N, Sisko MT, Soto-Rivera CL, Steil G, Wypij D, Nadkarni VM. Design and rationale of Heart and Lung Failure - Pediatric INsulin Titration Trial (HALF-PINT): A randomized clinical trial of tight glycemic control in hyperglycemic critically ill children. Contemp Clin Trials. 2017 02; 53:178-187. PMID: 28042054.
    Citations: 7     Fields:    Translation:Humans
  65. Natale J, Joseph J, Lebet R, Ascenzi J, Wypij D, Curley M. 6: RACE/ETHNIC DIFFERENCE IN CONSENT TO PARTICIPATE IN A LARGE, MULTISITE PEDIATRIC CRITICAL CARE RCT. Crit Care Med. 2016 Dec; 44(12 Suppl 1):88. PMID: 27849686.
    Citations:    
  66. Grant MJ, Schneider JB, Asaro LA, Dodson BL, Hall BA, Simone SL, Cowl AS, Munkwitz MM, Wypij D, Curley MA. Dexmedetomidine Use in Critically Ill Children With Acute Respiratory Failure. Pediatr Crit Care Med. 2016 12; 17(12):1131-1141. PMID: 27654816.
    Citations: 11     Fields:    Translation:Humans
  67. Rollins CK, Asaro LA, Akhondi-Asl A, Kussman BD, Rivkin MJ, Bellinger DC, Warfield SK, Wypij D, Newburger JW, Soul JS. White Matter Volume Predicts Language Development in Congenital Heart Disease. J Pediatr. 2017 02; 181:42-48.e2. PMID: 27837950.
    Citations: 15     Fields:    Translation:Humans
  68. Mills KI, Kaza AK, Walsh BK, Bond HC, Ford M, Wypij D, Thiagarajan RR, Almodovar MC, Quinonez LG, Baird CW, Emani SE, Pigula FA, DiNardo JA, Kheir JN. Phosphodiesterase Inhibitor-Based Vasodilation Improves Oxygen Delivery and Clinical Outcomes Following Stage 1 Palliation. J Am Heart Assoc. 2016 11 02; 5(11). PMID: 27806964.
    Citations: 1     Fields:    Translation:Humans
  69. Calderon J, Stopp C, Wypij D, DeMaso DR, Rivkin M, Newburger JW, Bellinger DC. Early-Term Birth in Single-Ventricle Congenital Heart Disease After the Fontan Procedure: Neurodevelopmental and Psychiatric Outcomes. J Pediatr. 2016 12; 179:96-103. PMID: 27692462.
    Citations: 9     Fields:    Translation:Humans
  70. Bateman ST, Borasino S, Asaro LA, Cheifetz IM, Diane S, Wypij D, Curley MA. Reply: It Is Too Early to Say No Place for High-Frequency Oscillatory Ventilation in Children with Respiratory Failure. Am J Respir Crit Care Med. 2016 08 15; 194(4):522. PMID: 27525465.
    Citations:    Fields:    Translation:Humans
  71. Bateman ST, Borasino S, Asaro LA, Cheifetz IM, Diane S, Wypij D, Curley MA. Reply: Do We Really Know How to Use High-Frequency Oscillatory Ventilation in Critically Ill Children? Am J Respir Crit Care Med. 2016 05 01; 193(9):1068-9. PMID: 27128709.
    Citations: 1     Fields:    Translation:Humans
  72. Sadhwani A, Asaro LA, Goldberg C, Ware J, Butcher J, Gaies M, Smith C, Alexander JL, Wypij D, Agus MS. Impact of Tight Glycemic Control on Neurodevelopmental Outcomes at 1 Year of Age for Children with Congenital Heart Disease: A Randomized Controlled Trial. J Pediatr. 2016 07; 174:193-198.e2. PMID: 27112038.
    Citations: 13     Fields:    Translation:Humans
  73. Bateman ST, Borasino S, Asaro LA, Cheifetz IM, Diane S, Wypij D, Curley MA. Early High-Frequency Oscillatory Ventilation in Pediatric Acute Respiratory Failure. A Propensity Score Analysis. Am J Respir Crit Care Med. 2016 Mar 01; 193(5):495-503. PMID: 26492410.
    Citations: 31     Fields:    Translation:Humans
  74. Rosario M, Li F, Wypij D, Roberts AL, Corliss HL, Charlton BM, Frazier AL, Austin SB. Disparities by Sexual Orientation in Frequent Engagement in Cancer-Related Risk Behaviors: A 12-Year Follow-Up. Am J Public Health. 2016 Apr; 106(4):698-706. PMID: 26794176.
    Citations: 15     Fields:    Translation:Humans
  75. Best KM, Asaro LA, Franck LS, Wypij D, Curley MA. Patterns of Sedation Weaning in Critically Ill Children Recovering From Acute Respiratory Failure. Pediatr Crit Care Med. 2016 Jan; 17(1):19-29. PMID: 26509816.
    Citations: 7     Fields:    Translation:Humans
  76. Bellinger DC, Watson CG, Rivkin MJ, Robertson RL, Roberts AE, Stopp C, Dunbar-Masterson C, Bernson D, DeMaso DR, Wypij D, Newburger JW. Neuropsychological Status and Structural Brain Imaging in Adolescents With Single Ventricle Who Underwent the Fontan Procedure. J Am Heart Assoc. 2015 Dec 14; 4(12). PMID: 26667085.
    Citations: 29     Fields:    Translation:Humans
  77. Watson CG, Asaro LA, Wypij D, Robertson RL, Newburger JW, Rivkin MJ. Altered Gray Matter in Adolescents with d-Transposition of the Great Arteries. J Pediatr. 2016 Feb; 169:36-43.e1. PMID: 26553098.
    Citations: 10     Fields:    Translation:Humans
  78. Fisher JG, Sparks EA, Khan FA, Alexander JL, Asaro LA, Wypij D, Gaies M, Modi BP, Duggan C, Agus MS, Yu YM, Jaksic T. Tight Glycemic Control With Insulin Does Not Affect Skeletal Muscle Degradation During the Early Postoperative Period Following Pediatric Cardiac Surgery. Pediatr Crit Care Med. 2015 Jul; 16(6):515-21. PMID: 25850865.
    Citations: 3     Fields:    Translation:Humans
  79. Curley MA, Wypij D, Matthay MA. Sedation protocol for critically ill pediatric patients--reply. JAMA. 2015 May 05; 313(17):1754-5. PMID: 25942731.
    Citations: 1     Fields:    Translation:Humans
  80. Gaynor JW, Stopp C, Wypij D, Andropoulos DB, Atallah J, Atz AM, Beca J, Donofrio MT, Duncan K, Ghanayem NS, Goldberg CS, Hövels-Gürich H, Ichida F, Jacobs JP, Justo R, Latal B, Li JS, Mahle WT, McQuillen PS, Menon SC, Pemberton VL, Pike NA, Pizarro C, Shekerdemian LS, Synnes A, Williams I, Bellinger DC, Newburger JW. Neurodevelopmental outcomes after cardiac surgery in infancy. Pediatrics. 2015 May; 135(5):816-25. PMID: 25917996.
    Citations: 95     Fields:    Translation:Humans
  81. Curley MA, Wypij D, Watson RS, Grant MJ, Asaro LA, Cheifetz IM, Dodson BL, Franck LS, Gedeit RG, Angus DC, Matthay MA. Protocolized sedation vs usual care in pediatric patients mechanically ventilated for acute respiratory failure: a randomized clinical trial. JAMA. 2015 Jan 27; 313(4):379-89. PMID: 25602358.
    Citations: 101     Fields:    Translation:Humans
  82. Neal AE, Stopp C, Wypij D, Bellinger DC, Dunbar-Masterson C, DeMaso DR, Newburger JW. Predictors of health-related quality of life in adolescents with tetralogy of Fallot. J Pediatr. 2015 Jan; 166(1):132-8. PMID: 25444004.
    Citations: 14     Fields:    Translation:Humans
  83. Staveski SL, Lincoln PA, Fineman LD, Asaro LA, Wypij D, Curley MA. Nurse decision making regarding the use of analgesics and sedatives in the pediatric cardiac ICU. Pediatr Crit Care Med. 2014 Oct; 15(8):691-7. PMID: 25080151.
    Citations: 2     Fields:    Translation:Humans
  84. Rollins CK, Watson CG, Asaro LA, Wypij D, Vajapeyam S, Bellinger DC, DeMaso DR, Robertson RL, Newburger JW, Rivkin MJ. White matter microstructure and cognition in adolescents with congenital heart disease. J Pediatr. 2014 Nov; 165(5):936-44.e1-2. PMID: 25217200.
    Citations: 48     Fields:    Translation:Humans
  85. Rosario M, Reisner SL, Corliss HL, Wypij D, Calzo J, Austin SB. Sexual-orientation disparities in substance use in emerging adults: a function of stress and attachment paradigms. Psychol Addict Behav. 2014 Sep; 28(3):790-804. PMID: 25134050.
    Citations: 27     Fields:    Translation:Humans
  86. DeMaso DR, Labella M, Taylor GA, Forbes PW, Stopp C, Bellinger DC, Rivkin MJ, Wypij D, Newburger JW. Psychiatric disorders and function in adolescents with d-transposition of the great arteries. J Pediatr. 2014 Oct; 165(4):760-6. PMID: 25063716.
    Citations: 20     Fields:    Translation:Humans
  87. Cheng HH, Wypij D, Laussen PC, Bellinger DC, Stopp CD, Soul JS, Newburger JW, Kussman BD. Cerebral blood flow velocity and neurodevelopmental outcome in infants undergoing surgery for congenital heart disease. Ann Thorac Surg. 2014 Jul; 98(1):125-32. PMID: 24820395.
    Citations: 9     Fields:    Translation:Humans
  88. Agus MS, Asaro LA, Steil GM, Alexander JL, Silverman M, Wypij D, Gaies MG. Tight glycemic control after pediatric cardiac surgery in high-risk patient populations: a secondary analysis of the safe pediatric euglycemia after cardiac surgery trial. Circulation. 2014 Jun 03; 129(22):2297-304. PMID: 24671945.
    Citations: 11     Fields:    Translation:Humans
  89. Decourcey DD, Steil G, Wypij D, Agus M. The authors reply. Pediatr Crit Care Med. 2014 Mar; 15(3):285-6. PMID: 24608506.
    Citations:    Fields:    Translation:Humans
  90. Bellinger DC, Rivkin MJ, DeMaso D, Robertson RL, Stopp C, Dunbar-Masterson C, Wypij D, Newburger JW. Adolescents with tetralogy of Fallot: neuropsychological assessment and structural brain imaging. Cardiol Young. 2015 Feb; 25(2):338-47. PMID: 24512980.
    Citations: 31     Fields:    Translation:Humans
  91. Odegard KC, Bergersen L, Thiagarajan R, Clark L, Shukla A, Wypij D, Laussen PC. The frequency of cardiac arrests in patients with congenital heart disease undergoing cardiac catheterization. Anesth Analg. 2014 Jan; 118(1):175-82. PMID: 23749445.
    Citations: 18     Fields:    Translation:Humans
  92. Decourcey DD, Steil GM, Wypij D, Agus MS. Increasing use of hypertonic saline over mannitol in the treatment of symptomatic cerebral edema in pediatric diabetic ketoacidosis: an 11-year retrospective analysis of mortality*. Pediatr Crit Care Med. 2013 Sep; 14(7):694-700. PMID: 23863818.
    Citations: 14     Fields:    Translation:Humans
  93. Siow E, Wypij D, Berry P, Hickey P, Curley MA. The effect of continuity in nursing care on patient outcomes in the pediatric intensive care unit. J Nurs Adm. 2013 Jul-Aug; 43(7-8):394-402. PMID: 23892304.
    Citations: 9     Fields:    Translation:Humans
  94. Rosario M, Reisner SL, Corliss HL, Wypij D, Frazier AL, Austin SB. Disparities in depressive distress by sexual orientation in emerging adults: the roles of attachment and stress paradigms. Arch Sex Behav. 2014 Jul; 43(5):901-16. PMID: 23780518.
    Citations: 23     Fields:    Translation:Humans
  95. Polito A, Barrett CS, Wypij D, Rycus PT, Netto R, Cogo PE, Thiagarajan RR. Neurologic complications in neonates supported with extracorporeal membrane oxygenation. An analysis of ELSO registry data. Intensive Care Med. 2013 Sep; 39(9):1594-601. PMID: 23749154.
    Citations: 38     Fields:    Translation:Humans
  96. Costello JM, Clapper TC, Wypij D. Minimizing complications associated with percutaneous central venous catheter placement in children: recent advances. Pediatr Crit Care Med. 2013 Mar; 14(3):273-83. PMID: 23392365.
    Citations: 11     Fields:    Translation:Humans
  97. Shuhaiber J, Shin AY, Gossett JG, Wypij D, Backer CL, Hanley FL, Khan MS, Fraser CD, Jacques F, Manning PB, Van Arsdell G, Mayer JE, Costello JM. Surgical management of neonatal atrioventricular septal defect with aortic arch obstruction. Ann Thorac Surg. 2013 Jun; 95(6):2071-7. PMID: 23415240.
    Citations:    Fields:    Translation:Humans
  98. Rivkin MJ, Watson CG, Scoppettuolo LA, Wypij D, Vajapeyam S, Bellinger DC, DeMaso DR, Robertson RL, Newburger JW. Adolescents with D-transposition of the great arteries repaired in early infancy demonstrate reduced white matter microstructure associated with clinical risk factors. J Thorac Cardiovasc Surg. 2013 Sep; 146(3):543-9.e1. PMID: 23375991.
    Citations: 36     Fields:    Translation:Humans
  99. Gaies MG, Langer M, Alexander J, Steil GM, Ware J, Wypij D, Laussen PC, Newburger JW, Goldberg CS, Pigula FA, Shukla AC, Duggan CP, Agus MS. Design and rationale of safe pediatric euglycemia after cardiac surgery: a randomized controlled trial of tight glycemic control after pediatric cardiac surgery. Pediatr Crit Care Med. 2013 Feb; 14(2):148-56. PMID: 22805161.
    Citations: 7     Fields:    Translation:Humans
  100. Roberts AL, Rosario M, Corliss HL, Wypij D, Lightdale JR, Austin SB. Sexual orientation and functional pain in U.S. young adults: the mediating role of childhood abuse. PLoS One. 2013; 8(1):e54702. PMID: 23355890.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  101. Ott MQ, Wypij D, Corliss HL, Rosario M, Reisner SL, Gordon AR, Austin SB. Repeated changes in reported sexual orientation identity linked to substance use behaviors in youth. J Adolesc Health. 2013 Apr; 52(4):465-72. PMID: 23298999.
    Citations: 21     Fields:    Translation:Humans
  102. Agus MS, Steil GM, Wypij D, Costello JM, Laussen PC, Langer M, Alexander JL, Scoppettuolo LA, Pigula FA, Charpie JR, Ohye RG, Gaies MG. Tight glycemic control versus standard care after pediatric cardiac surgery. N Engl J Med. 2012 Sep 27; 367(13):1208-19. PMID: 22957521.
    Citations: 75     Fields:    Translation:Humans
  103. Costello JM, O'Brien M, Wypij D, Shubert J, Salvin JW, Newburger JW, Laussen PC, Arnold JH, Fynn-Thompson F, Thiagarajan RR. Quality of life of pediatric cardiac patients who previously required extracorporeal membrane oxygenation. Pediatr Crit Care Med. 2012 Jul; 13(4):428-34. PMID: 22067987.
    Citations: 10     Fields:    Translation:Humans
  104. Corliss HL, Wadler BM, Jun HJ, Rosario M, Wypij D, Frazier AL, Austin SB. Sexual-orientation disparities in cigarette smoking in a longitudinal cohort study of adolescents. Nicotine Tob Res. 2013 Jan; 15(1):213-22. PMID: 22581940.
    Citations: 64     Fields:    Translation:Humans
  105. Mazwi ML, Brown DW, Marshall AC, Pigula FA, Laussen PC, Polito A, Wypij D, Costello JM. Unplanned reinterventions are associated with postoperative mortality in neonates with critical congenital heart disease. J Thorac Cardiovasc Surg. 2013 Mar; 145(3):671-7. PMID: 22578897.
    Citations: 6     Fields:    Translation:Humans
  106. Grant MJ, Scoppettuolo LA, Wypij D, Curley MA. Prospective evaluation of sedation-related adverse events in pediatric patients ventilated for acute respiratory failure. Crit Care Med. 2012 Apr; 40(4):1317-23. PMID: 22425823.
    Citations: 12     Fields:    Translation:Humans
  107. Franck LS, Scoppettuolo LA, Wypij D, Curley MAQ. Validity and generalizability of the Withdrawal Assessment Tool-1 (WAT-1) for monitoring iatrogenic withdrawal syndrome in pediatric patients. Pain. 2012 Jan; 153(1):142-148. PMID: 22093817.
    Citations: 38     Fields:    Translation:Humans
  108. Bellinger DC, Wypij D, Rivkin MJ, DeMaso DR, Robertson RL, Dunbar-Masterson C, Rappaport LA, Wernovsky G, Jonas RA, Newburger JW. Adolescents with d-transposition of the great arteries corrected with the arterial switch procedure: neuropsychological assessment and structural brain imaging. Circulation. 2011 Sep 20; 124(12):1361-9. PMID: 21875911.
    Citations: 122     Fields:    Translation:Humans
  109. Cheng HH, Almodovar MC, Laussen PC, Wypij D, Polito A, Brown DW, Emani SM, Pigula FA, Allan CK, Costello JM. Outcomes and risk factors for mortality in premature neonates with critical congenital heart disease. Pediatr Cardiol. 2011 Dec; 32(8):1139-46. PMID: 21713439.
    Citations: 21     Fields:    Translation:Humans
  110. Friedman KG, Salvin JW, Wypij D, Gurmu Y, Bacha EA, Brown DW, Laussen PC, Scheurer MA. Risk factors for failed staged palliation after bidirectional Glenn in infants who have undergone stage one palliation. Eur J Cardiothorac Surg. 2011 Oct; 40(4):1000-6. PMID: 21377892.
    Citations: 12     Fields:    Translation:Humans
  111. Kipps AK, Wypij D, Thiagarajan RR, Bacha EA, Newburger JW. Blood transfusion is associated with prolonged duration of mechanical ventilation in infants undergoing reparative cardiac surgery. Pediatr Crit Care Med. 2011 Jan; 12(1):52-6. PMID: 20453699.
    Citations: 24     Fields:    Translation:Humans
  112. Salvin JW, Scheurer MA, Laussen PC, Wypij D, Polito A, Bacha EA, Pigula FA, McGowan FX, Costello JM, Thiagarajan RR. Blood transfusion after pediatric cardiac surgery is associated with prolonged hospital stay. Ann Thorac Surg. 2011 Jan; 91(1):204-10. PMID: 21172513.
    Citations: 25     Fields:    Translation:Humans
  113. Lell B, Köhler C, Wamola B, Olola CH, Kivaya E, Kokwaro G, Wypij D, Mithwani S, Taylor TE, Kremsner PG, Newton CR. Pentoxifylline as an adjunct therapy in children with cerebral malaria. Malar J. 2010 Dec 21; 9:368. PMID: 21176151.
    Citations: 11     Fields:    Translation:Humans
  114. Ott MQ, Corliss HL, Wypij D, Rosario M, Austin SB. Stability and change in self-reported sexual orientation identity in young people: application of mobility metrics. Arch Sex Behav. 2011 Jun; 40(3):519-32. PMID: 21125325.
    Citations: 62     Fields:    Translation:Humans
  115. Kane DA, Thiagarajan RR, Wypij D, Scheurer MA, Fynn-Thompson F, Emani S, del Nido PJ, Betit P, Laussen PC. Rapid-response extracorporeal membrane oxygenation to support cardiopulmonary resuscitation in children with cardiac disease. Circulation. 2010 Sep 14; 122(11 Suppl):S241-8. PMID: 20837920.
    Citations: 48     Fields:    Translation:Humans
  116. Allan CK, Newburger JW, McGrath E, Elder J, Psoinos C, Laussen PC, del Nido PJ, Wypij D, McGowan FX. The relationship between inflammatory activation and clinical outcome after infant cardiopulmonary bypass. Anesth Analg. 2010 Nov; 111(5):1244-51. PMID: 20829561.
    Citations: 42     Fields:    Translation:Humans
  117. Kussman BD, Wypij D, Laussen PC, Soul JS, Bellinger DC, DiNardo JA, Robertson R, Pigula FA, Jonas RA, Newburger JW. Relationship of intraoperative cerebral oxygen saturation to neurodevelopmental outcome and brain magnetic resonance imaging at 1 year of age in infants undergoing biventricular repair. Circulation. 2010 Jul 20; 122(3):245-54. PMID: 20606124.
    Citations: 37     Fields:    Translation:Humans
  118. Rajagopal SK, Almond CS, Laussen PC, Rycus PT, Wypij D, Thiagarajan RR. Extracorporeal membrane oxygenation for the support of infants, children, and young adults with acute myocarditis: a review of the Extracorporeal Life Support Organization registry. Crit Care Med. 2010 Feb; 38(2):382-7. PMID: 19789437.
    Citations: 40     Fields:    Translation:Humans
  119. Corliss HL, Rosario M, Wypij D, Wylie SA, Frazier AL, Austin SB. Sexual orientation and drug use in a longitudinal cohort study of U.S. adolescents. Addict Behav. 2010 May; 35(5):517-21. PMID: 20061091.
    Citations: 102     Fields:    Translation:Humans
  120. Surkan PJ, Wypij D, Trachtenberg F, Daniel DB, Barregard L, McKinlay S, Bellinger DC. Neuropsychological function in school-age children with low mercury exposures. Environ Res. 2009 Aug; 109(6):728-33. PMID: 19464677.
    Citations: 4     Fields:    Translation:Humans
  121. Austin SB, Ziyadeh NJ, Corliss HL, Rosario M, Wypij D, Haines J, Camargo CA, Field AE. Sexual orientation disparities in purging and binge eating from early to late adolescence. J Adolesc Health. 2009 Sep; 45(3):238-45. PMID: 19699419.
    Citations: 66     Fields:    Translation:Humans
  122. Soul JS, Robertson RL, Wypij D, Bellinger DC, Visconti KJ, du Plessis AJ, Kussman BD, Scoppettuolo LA, Pigula F, Jonas RA, Newburger JW. Subtle hemorrhagic brain injury is associated with neurodevelopmental impairment in infants with repaired congenital heart disease. J Thorac Cardiovasc Surg. 2009 Aug; 138(2):374-81. PMID: 19619781.
    Citations: 16     Fields:    Translation:Humans
  123. Kussman BD, Wypij D, DiNardo JA, Newburger JW, Mayer JE, del Nido PJ, Bacha EA, Pigula F, McGrath E, Laussen PC. Cerebral oximetry during infant cardiac surgery: evaluation and relationship to early postoperative outcome. Anesth Analg. 2009 Apr; 108(4):1122-31. PMID: 19299774.
    Citations: 9     Fields:    Translation:Humans
  124. Austin SB, Ziyadeh NJ, Corliss HL, Haines J, Rockett HR, Wypij D, Field AE. Sexual orientation disparities in weight status in adolescence: findings from a prospective study. Obesity (Silver Spring). 2009 Sep; 17(9):1776-82. PMID: 19300430.
    Citations: 33     Fields:    Translation:Humans
  125. Kremsner PG, Valim C, Missinou MA, Olola C, Krishna S, Issifou S, Kombila M, Bwanaisa L, Mithwani S, Newton CR, Agbenyega T, Pinder M, Bojang K, Wypij D, Taylor T. Prognostic value of circulating pigmented cells in African children with malaria. J Infect Dis. 2009 Jan 01; 199(1):142-50. PMID: 19086817.
    Citations: 23     Fields:    Translation:HumansAnimals
  126. Bellinger DC, Newburger JW, Wypij D, Kuban KC, duPlesssis AJ, Rappaport LA. Behaviour at eight years in children with surgically corrected transposition: The Boston Circulatory Arrest Trial. Cardiol Young. 2009 Feb; 19(1):86-97. PMID: 19079812.
    Citations: 28     Fields:    Translation:Humans
  127. Corliss HL, Rosario M, Wypij D, Fisher LB, Austin SB. Sexual orientation disparities in longitudinal alcohol use patterns among adolescents: findings from the Growing Up Today Study. Arch Pediatr Adolesc Med. 2008 Nov; 162(11):1071-8. PMID: 18981356.
    Citations: 91     Fields:    Translation:Humans
  128. Valim C, Mezzetti M, Maguire J, Urdaneta M, Wypij D. Estimation of vaccine efficacy in a repeated measures study under heterogeneity of exposure or susceptibility to infection. Philos Trans A Math Phys Eng Sci. 2008 Jul 13; 366(1874):2347-60. PMID: 18407892.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  129. Newburger JW, Jonas RA, Soul J, Kussman BD, Bellinger DC, Laussen PC, Robertson R, Mayer JE, del Nido PJ, Bacha EA, Forbess JM, Pigula F, Roth SJ, Visconti KJ, du Plessis AJ, Farrell DM, McGrath E, Rappaport LA, Wypij D. Randomized trial of hematocrit 25% versus 35% during hypothermic cardiopulmonary bypass in infant heart surgery. J Thorac Cardiovasc Surg. 2008 Feb; 135(2):347-54, 354.e1-4. PMID: 18242267.
    Citations: 28     Fields:    Translation:Humans
  130. Wypij D, Jonas RA, Bellinger DC, Del Nido PJ, Mayer JE, Bacha EA, Forbess JM, Pigula F, Laussen PC, Newburger JW. The effect of hematocrit during hypothermic cardiopulmonary bypass in infant heart surgery: results from the combined Boston hematocrit trials. J Thorac Cardiovasc Surg. 2008 Feb; 135(2):355-60. PMID: 18242268.
    Citations: 29     Fields:    Translation:Humans
  131. Daily JP, Scanfeld D, Pochet N, Le Roch K, Plouffe D, Kamal M, Sarr O, Mboup S, Ndir O, Wypij D, Levasseur K, Thomas E, Tamayo P, Dong C, Zhou Y, Lander ES, Ndiaye D, Wirth D, Winzeler EA, Mesirov JP, Regev A. Distinct physiological states of Plasmodium falciparum in malaria-infected patients. Nature. 2007 Dec 13; 450(7172):1091-5. PMID: 18046333.
    Citations: 113     Fields:    Translation:HumansAnimalsCells
  132. Lesser LI, Ebbeling CB, Goozner M, Wypij D, Ludwig DS. Relationship between funding source and conclusion among nutrition-related scientific articles. PLoS Med. 2007 Jan; 4(1):e5. PMID: 17214504.
    Citations: 83     Fields:    Translation:HumansAnimalsPHPublic Health
  133. Agus MS, Javid PJ, Piper HG, Wypij D, Duggan CP, Ryan DP, Jaksic T. The effect of insulin infusion upon protein metabolism in neonates on extracorporeal life support. Ann Surg. 2006 Oct; 244(4):536-44. PMID: 16998362.
    Citations: 9     Fields:    Translation:Humans
  134. von Scheven E, Gordon CM, Wypij D, Wertz M, Gallagher KT, Bachrach L. Variable deficits of bone mineral despite chronic glucocorticoid therapy in pediatric patients with inflammatory diseases: a Glaser Pediatric Research Network study. J Pediatr Endocrinol Metab. 2006 Jun; 19(6):821-30. PMID: 16886590.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  135. Woods ER, Klein JD, Wingood GM, Rose ES, Wypij D, Harris SK, Diclemente RJ. Development of a new Adolescent Patient-Provider Interaction Scale (APPIS) for youth at risk for STDs/HIV. J Adolesc Health. 2006 Jun; 38(6):753.e1-7. PMID: 16730606.
    Citations: 10     Fields:    Translation:Humans
  136. Bartels DB, Wypij D, Wenzlaff P, Dammann O, Poets CF. Hospital volume and neonatal mortality among very low birth weight infants. Pediatrics. 2006 Jun; 117(6):2206-14. PMID: 16740866.
    Citations: 25     Fields:    Translation:Humans
  137. Bassin EB, Wypij D, Davis RB, Mittleman MA. Age-specific fluoride exposure in drinking water and osteosarcoma (United States). Cancer Causes Control. 2006 May; 17(4):421-8. PMID: 16596294.
    Citations: 31     Fields:    Translation:HumansPHPublic Health
  138. Taylor T, Olola C, Valim C, Agbenyega T, Kremsner P, Krishna S, Kwiatkowski D, Newton C, Missinou M, Pinder M, Wypij D. Standardized data collection for multi-center clinical studies of severe malaria in African children: establishing the SMAC network. Trans R Soc Trop Med Hyg. 2006 Jul; 100(7):615-22. PMID: 16551469.
    Citations: 52     Fields:    Translation:Humans
  139. Kussman BD, Wypij D, DiNardo JA, Newburger J, Jonas RA, Bartlett J, McGrath E, Laussen PC. An evaluation of bilateral monitoring of cerebral oxygen saturation during pediatric cardiac surgery. Anesth Analg. 2005 Nov; 101(5):1294-1300. PMID: 16243983.
    Citations: 4     Fields:    Translation:Humans
  140. Waltzman ML, Baskin M, Wypij D, Mooney D, Jones D, Fleisher G. A randomized clinical trial of the management of esophageal coins in children. Pediatrics. 2005 Sep; 116(3):614-9. PMID: 16140701.
    Citations: 22     Fields:    Translation:Humans
  141. Newton CR, Valim C, Krishna S, Wypij D, Olola C, Agbenyega T, Taylor TE. The prognostic value of measures of acid/base balance in pediatric falciparum malaria, compared with other clinical and laboratory parameters. Clin Infect Dis. 2005 Oct 01; 41(7):948-57. PMID: 16142658.
    Citations: 26     Fields:    Translation:Humans