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James Arthur Lederer, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AI148232 (LEDERER, JAMES A.) Jun 10, 2020 - May 31, 2025
    Adaptive Immune Regulation of Traumatic Injury
    Role: Principal Investigator
  2. U01AI138318 (LEDERER, JAMES A.) Apr 1, 2018 - Mar 31, 2023
    Therapy of acute radiation syndrome and its complications by mesenchymal stromal cells conditioned with Toll-like receptor 9 agonists
    Role: Principal Investigator
  3. P30AR070253 (NIGROVIC, PETER A) Aug 11, 2016 - Jul 31, 2026
    Joint Biology Consortium Resource-based Center
    Role: Co-Principal Investigator
  4. P30AR069625 (CLARK, RACHAEL ANN) Jul 19, 2016 - Apr 30, 2026
    Human Skin Disease Resource-based Center
    Role: Co-Principal Investigator
  5. U01AI107360 (LEDERER, JAMES A.) May 9, 2013 - Apr 30, 2019
    Restoring Immune Function Following Radiation Injuries by TLR9 Agonist Treatment
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Julé AM, Hoyt KJ, Wei K, Gutierrez-Arcelus M, Taylor ML, Ng J, Lederer JA, Case SM, Chang MH, Cohen EM, Dedeoglu F, Hazen MM, Hausmann JS, Halyabar O, Janssen E, Lo J, Lo MS, Meidan E, Roberts JE, Son MBF, Sundel RP, Lee PY, Chatila T, Nigrovic PA, Henderson LA. Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis. JCI Insight. 2021 Sep 22; 6(18). PMID: 34403374.
    Citations:    Fields:    
  2. Levescot A, Chang MH, Schnell J, Nelson-Maney N, Yan J, Martínez-Bonet M, Grieshaber-Bouyer R, Lee PY, Wei K, Blaustein RB, Morris A, Wactor A, Iwakura Y, Lederer JA, Rao DA, Charles JF, Nigrovic PA. IL-1ß-driven osteoclastogenic Tregs accelerate bone erosion in arthritis. J Clin Invest. 2021 09 15; 131(18). PMID: 34343136.
    Citations:    Fields:    
  3. Han J, Li G, Hou M, Ng J, Kwon MY, Xiong K, Liang X, Taglauer E, Shi Y, Mitsialis SA, Kourembanas S, El-Chemaly S, Lederer JA, Rosas IO, Perrella MA, Liu X. Intratracheal transplantation of trophoblast stem cells attenuates acute lung injury in mice. Stem Cell Res Ther. 2021 08 30; 12(1):487. PMID: 34461993.
    Citations:    Fields:    
  4. Wang D, Lin M, Utz B, Bosompem A, Guo Y, Daneshbod Y, Alford CE, Nettles SA, Scher J, Gagne EY, O'Neill M, Barrow L, Wojciechowska N, Keegan J, Mosse CA, Lederer JA, Kim AS. miR-378-3p Knockdown Recapitulates Many of the Features of Myelodysplastic Syndromes. Am J Pathol. 2021 11; 191(11):2009-2022. PMID: 34364880.
    Citations:    Fields:    
  5. Emmons TR, Giridharan T, Singel KL, Khan ANH, Ricciuti J, Howard K, Silva-Del Toro SL, Debreceni IL, Aarts CEM, Brouwer MC, Suzuki S, Kuijpers TW, Jongerius I, Allen LH, Ferreira VP, Schubart A, Sellner H, Eder J, Holland SM, Ram S, Lederer JA, Eng KH, Moysich KB, Odunsi K, Yaffe MB, Zsiros E, Segal BH. Mechanisms Driving Neutrophil-Induced T-cell Immunoparalysis in Ovarian Cancer. Cancer Immunol Res. 2021 07; 9(7):790-810. PMID: 33990375.
    Citations: 1     Fields:    
  6. Kwon MY, Ghanta S, Ng J, Castano AP, Han J, Ith B, Lederer JA, El-Chemaly S, Chung SW, Liu X, Perrella MA. Mesenchymal stromal cells expressing a dominant-negative high mobility group A1 transgene exhibit improved function during sepsis. J Leukoc Biol. 2021 10; 110(4):711-722. PMID: 33438259.
    Citations: 1     Fields:    Translation:AnimalsCells
  7. Chen Y, Zuiani A, Fischinger S, Mullur J, Atyeo C, Travers M, Lelis FJN, Pullen KM, Martin H, Tong P, Gautam A, Habibi S, Bensko J, Gakpo D, Feldman J, Hauser BM, Caradonna TM, Cai Y, Burke JS, Lin J, Lederer JA, Lam EC, Lavine CL, Seaman MS, Chen B, Schmidt AG, Balazs AB, Lauffenburger DA, Alter G, Wesemann DR. Quick COVID-19 Healers Sustain Anti-SARS-CoV-2 Antibody Production. Cell. 2020 12 10; 183(6):1496-1507.e16. PMID: 33171099.
    Citations: 52     Fields:    Translation:HumansCells
  8. Ng J, Guo F, Marneth AE, Ghanta S, Kwon MY, Keegan J, Liu X, Wright KT, Kamaz B, Cahill LA, Mullally A, Perrella MA, Lederer JA. Augmenting emergency granulopoiesis with CpG conditioned mesenchymal stromal cells in murine neutropenic sepsis. Blood Adv. 2020 10 13; 4(19):4965-4979. PMID: 33049055.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  9. Cahill LA, Joughin BA, Kwon WY, Itagaki K, Kirk CH, Shapiro NI, Otterbein LE, Yaffe MB, Lederer JA, Hauser CJ. Multiplexed Plasma Immune Mediator Signatures Can Differentiate Sepsis From NonInfective SIRS: American Surgical Association 2020 Annual Meeting Paper. Ann Surg. 2020 10; 272(4):604-610. PMID: 32932316.
    Citations: 1     Fields:    Translation:Humans
  10. Shrock E, Fujimura E, Kula T, Timms RT, Lee IH, Leng Y, Robinson ML, Sie BM, Li MZ, Chen Y, Logue J, Zuiani A, McCulloch D, Lelis FJN, Henson S, Monaco DR, Travers M, Habibi S, Clarke WA, Caturegli P, Laeyendecker O, Piechocka-Trocha A, Li JZ, Khatri A, Chu HY, Villani AC, Kays K, Goldberg MB, Hacohen N, Filbin MR, Yu XG, Walker BD, Wesemann DR, Larman HB, Lederer JA, Elledge SJ. Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity. Science. 2020 11 27; 370(6520). PMID: 32994364.
    Citations: 109     Fields:    Translation:HumansCells
  11. Khalsa JK, Cheng N, Keegan J, Chaudry A, Driver J, Bi WL, Lederer J, Shah K. Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types. Nat Commun. 2020 08 06; 11(1):3912. PMID: 32764562.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  12. Yamakawa K, Tajima G, Keegan JW, Nakahori Y, Guo F, Seshadri AJ, Cahill LA, Lederer JA. Trauma induces expansion and activation of a memory-like Treg population. J Leukoc Biol. 2021 03; 109(3):645-656. PMID: 32531832.
    Citations:    Fields:    Translation:AnimalsCells
  13. Kwon MY, Ghanta S, Ng J, Tsoyi K, Lederer JA, Bronson RT, El-Chemaly S, Chung SW, Liu X, Perrella MA. Expression of Stromal Cell-Derived Factor-1 by Mesenchymal Stromal Cells Impacts Neutrophil Function During Sepsis. Crit Care Med. 2020 05; 48(5):e409-e417. PMID: 32167490.
    Citations: 2     Fields:    Translation:AnimalsCells
  14. Henderson LA, Hoyt KJ, Lee PY, Rao DA, Jonsson AH, Nguyen JP, Rutherford K, Julé AM, Charbonnier LM, Case S, Chang MH, Cohen EM, Dedeoglu F, Fuhlbrigge RC, Halyabar O, Hazen MM, Janssen E, Kim S, Lo J, Lo MS, Meidan E, Son MBF, Sundel RP, Stoll ML, Nusbaum C, Lederer JA, Chatila TA, Nigrovic PA. Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis. JCI Insight. 2020 03 26; 5(6). PMID: 32213704.
    Citations: 8     Fields:    Translation:HumansCells
  15. Hanidziar D, Nakahori Y, Cahill LA, Gallo D, Keegan JW, Nguyen JP, Otterbein LE, Lederer JA, Robson SC. Characterization of pulmonary immune responses to hyperoxia by high-dimensional mass cytometry analyses. Sci Rep. 2020 03 13; 10(1):4677. PMID: 32170168.
    Citations: 5     Fields:    Translation:AnimalsCells
  16. Cahill LA, Guo F, Nguyen J, Zhang F, Seshadri A, Keegan J, Hauser CJ, Otterbein LE, Robson S, Shaefi S, Yaffe MB, Lederer JA. Circulating Factors in Trauma Plasma Activate Specific Human Immune Cell Subsets. Injury. 2020 Apr; 51(4):819-829. PMID: 32171537.
    Citations: 1     Fields:    Translation:HumansCells
  17. Hoover P, Der E, Berthier CC, Arazi A, Lederer JA, James JA, Buyon J, Petri M, Belmont HM, Izmirly P, Wofsy D, Hacohen N, Diamond B, Putterman C, Davidson A. Accelerating Medicines Partnership: Organizational Structure and Preliminary Data From the Phase 1 Studies of Lupus Nephritis. Arthritis Care Res (Hoboken). 2020 02; 72(2):233-242. PMID: 31502417.
    Citations: 3     Fields:    Translation:Humans
  18. Bocharnikov AV, Keegan J, Wacleche VS, Cao Y, Fonseka CY, Wang G, Muise ES, Zhang KX, Arazi A, Keras G, Li ZJ, Qu Y, Gurish MF, Petri M, Buyon JP, Putterman C, Wofsy D, James JA, Guthridge JM, Diamond B, Anolik JH, Mackey MF, Alves SE, Nigrovic PA, Costenbader KH, Brenner MB, Lederer JA, Rao DA. PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21. JCI Insight. 2019 10 17; 4(20). PMID: 31536480.
    Citations: 22     Fields:    Translation:HumansCells
  19. Arazi A, Rao DA, Berthier CC, Davidson A, Liu Y, Hoover PJ, Chicoine A, Eisenhaure TM, Jonsson AH, Li S, Lieb DJ, Zhang F, Slowikowski K, Browne EP, Noma A, Sutherby D, Steelman S, Smilek DE, Tosta P, Apruzzese W, Massarotti E, Dall'Era M, Park M, Kamen DL, Furie RA, Payan-Schober F, Pendergraft WF, McInnis EA, Buyon JP, Petri MA, Putterman C, Kalunian KC, Woodle ES, Lederer JA, Hildeman DA, Nusbaum C, Raychaudhuri S, Kretzler M, Anolik JH, Brenner MB, Wofsy D, Hacohen N, Diamond B. Publisher Correction: The immune cell landscape in kidneys of patients with lupus nephritis. Nat Immunol. 2019 Oct; 20(10):1404. PMID: 31409923.
    Citations:    Fields:    
  20. Lee PY, Nelson-Maney N, Huang Y, Levescot A, Wang Q, Wei K, Cunin P, Li Y, Lederer JA, Zhuang H, Han S, Kim EY, Reeves WH, Nigrovic PA. High-dimensional analysis reveals a pathogenic role of inflammatory monocytes in experimental diffuse alveolar hemorrhage. JCI Insight. 2019 08 08; 4(15). PMID: 31391335.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  21. Seshadri A, Brat GA, Yorkgitis BK, Giangola M, Keegan J, Nguyen JP, Li W, Nakahori Y, Wada T, Hauser C, Salim A, Askari R, Lederer JA. Altered monocyte and NK cell phenotypes correlate with posttrauma infection. J Trauma Acute Care Surg. 2019 08; 87(2):337-341. PMID: 31008865.
    Citations: 3     Fields:    Translation:HumansCells
  22. Arazi A, Rao DA, Berthier CC, Davidson A, Liu Y, Hoover PJ, Chicoine A, Eisenhaure TM, Jonsson AH, Li S, Lieb DJ, Zhang F, Slowikowski K, Browne EP, Noma A, Sutherby D, Steelman S, Smilek DE, Tosta P, Apruzzese W, Massarotti E, Dall'Era M, Park M, Kamen DL, Furie RA, Payan-Schober F, Pendergraft WF, McInnis EA, Buyon JP, Petri MA, Putterman C, Kalunian KC, Woodle ES, Lederer JA, Hildeman DA, Nusbaum C, Raychaudhuri S, Kretzler M, Anolik JH, Brenner MB, Wofsy D, Hacohen N, Diamond B. The immune cell landscape in kidneys of patients with lupus nephritis. Nat Immunol. 2019 07; 20(7):902-914. PMID: 31209404.
    Citations: 106     Fields:    Translation:HumansCells
  23. Zhang F, Wei K, Slowikowski K, Fonseka CY, Rao DA, Kelly S, Goodman SM, Tabechian D, Hughes LB, Salomon-Escoto K, Watts GFM, Jonsson AH, Rangel-Moreno J, Meednu N, Rozo C, Apruzzese W, Eisenhaure TM, Lieb DJ, Boyle DL, Mandelin AM, Boyce BF, DiCarlo E, Gravallese EM, Gregersen PK, Moreland L, Firestein GS, Hacohen N, Nusbaum C, Lederer JA, Perlman H, Pitzalis C, Filer A, Holers VM, Bykerk VP, Donlin LT, Anolik JH, Brenner MB, Raychaudhuri S. Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry. Nat Immunol. 2019 07; 20(7):928-942. PMID: 31061532.
    Citations: 161     Fields:    Translation:HumansCells
  24. Fonseka CY, Rao DA, Teslovich NC, Korsunsky I, Hannes SK, Slowikowski K, Gurish MF, Donlin LT, Lederer JA, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, Todd DJ, Bykerk VP, Karlson EW, Ermann J, Lee YC, Brenner MB, Raychaudhuri S. Mixed-effects association of single cells identifies an expanded effector CD4+ T cell subset in rheumatoid arthritis. Sci Transl Med. 2018 10 17; 10(463). PMID: 30333237.
    Citations: 31     Fields:    Translation:HumansCells
  25. Ledderose C, Liu K, Kondo Y, Slubowski CJ, Dertnig T, Denicoló S, Arbab M, Hubner J, Konrad K, Fakhari M, Lederer JA, Robson SC, Visner GA, Junger WG. Purinergic P2X4 receptors and mitochondrial ATP production regulate T cell migration. J Clin Invest. 2018 08 01; 128(8):3583-3594. PMID: 29894310.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  26. Donlin LT, Rao DA, Wei K, Slowikowski K, McGeachy MJ, Turner JD, Meednu N, Mizoguchi F, Gutierrez-Arcelus M, Lieb DJ, Keegan J, Muskat K, Hillman J, Rozo C, Ricker E, Eisenhaure TM, Li S, Browne EP, Chicoine A, Sutherby D, Noma A, Nusbaum C, Kelly S, Pernis AB, Ivashkiv LB, Goodman SM, Robinson WH, Utz PJ, Lederer JA, Gravallese EM, Boyce BF, Hacohen N, Pitzalis C, Gregersen PK, Firestein GS, Raychaudhuri S, Moreland LW, Holers VM, Bykerk VP, Filer A, Boyle DL, Brenner MB, Anolik JH. Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue Arthritis Res Ther. 2018 07 11; 20(1):139. PMID: 29996944.
    Citations: 33     Fields:    Translation:Humans
  27. Baron RM, Kwon MY, Castano AP, Ghanta S, Riascos-Bernal DF, Lopez-Guzman S, Macias AA, Ith B, Schissel SL, Lederer JA, Reeves R, Yet SF, Layne MD, Liu X, Perrella MA. Frontline Science: Targeted expression of a dominant-negative high mobility group A1 transgene improves outcome in sepsis. J Leukoc Biol. 2018 10; 104(4):677-689. PMID: 29975792.
    Citations: 2     Fields:    Translation:AnimalsCells
  28. Mizoguchi F, Slowikowski K, Wei K, Marshall JL, Rao DA, Chang SK, Nguyen HN, Noss EH, Turner JD, Earp BE, Blazar PE, Wright J, Simmons BP, Donlin LT, Kalliolias GD, Goodman SM, Bykerk VP, Ivashkiv LB, Lederer JA, Hacohen N, Nigrovic PA, Filer A, Buckley CD, Raychaudhuri S, Brenner MB. Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis. Nat Commun. 2018 02 23; 9(1):789. PMID: 29476097.
    Citations: 103     Fields:    Translation:HumansCells
  29. Seshadri A, Brat GA, Yorkgitis BK, Keegan J, Dolan J, Salim A, Askari R, Lederer JA. Phenotyping the Immune Response to Trauma: A Multiparametric Systems Immunology Approach. Crit Care Med. 2017 Sep; 45(9):1523-1530. PMID: 28671900.
    Citations: 22     Fields:    Translation:HumansCells
  30. Rao DA, Gurish MF, Marshall JL, Slowikowski K, Fonseka CY, Liu Y, Donlin LT, Henderson LA, Wei K, Mizoguchi F, Teslovich NC, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, Lee YC, Todd DJ, Bykerk VP, Goodman SM, Pernis AB, Ivashkiv LB, Karlson EW, Nigrovic PA, Filer A, Buckley CD, Lederer JA, Raychaudhuri S, Brenner MB. Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. Nature. 2017 02 01; 542(7639):110-114. PMID: 28150777.
    Citations: 195     Fields:    Translation:HumansCells
  31. Seshadri A, Brat G, Yorkgitis B, Keegan J, Dolan J, Salim A, Askari R, Lederer J. 630: THE HUMAN RESPONSE TO TRAUMA: A SYSTEMS IMMUNOLOGY APPROACH. Crit Care Med. 2016 Dec; 44(12 Suppl 1):234. PMID: 27850269.
  32. Zhao G, Zaidi TS, Bozkurt-Guzel C, Zaidi TH, Lederer JA, Priebe GP, Pier GB. Efficacy of Antibody to PNAG Against Keratitis Caused by Fungal Pathogens. Invest Ophthalmol Vis Sci. 2016 12 01; 57(15):6797-6804. PMID: 28002842.
    Citations: 5     Fields:    Translation:Animals
  33. Gao P, Rong HH, Lu T, Tang G, Si LY, Lederer JA, Xiong W. The CD4/CD8 ratio is associated with coronary artery disease (CAD) in elderly Chinese patients. Int Immunopharmacol. 2017 Jan; 42:39-43. PMID: 27866071.
    Citations: 4     Fields:    Translation:HumansCells
  34. Foks AC, Engelbertsen D, Kuperwaser F, Alberts-Grill N, Gonen A, Witztum JL, Lederer J, Jarolim P, DeKruyff RH, Freeman GJ, Lichtman AH. Blockade of Tim-1 and Tim-4 Enhances Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice. Arterioscler Thromb Vasc Biol. 2016 Mar; 36(3):456-65. PMID: 26821944.
    Citations: 20     Fields:    Translation:AnimalsCells
  35. Wanke-Jellinek L, Keegan JW, Dolan JW, Guo F, Chen J, Lederer JA. Beneficial Effects of CpG-Oligodeoxynucleotide Treatment on Trauma and Secondary Lung Infection. J Immunol. 2016 Jan 15; 196(2):767-77. PMID: 26673136.
    Citations: 2     Fields:    Translation:AnimalsCells
  36. Engelbertsen D, Foks AC, Alberts-Grill N, Kuperwaser F, Chen T, Lederer JA, Jarolim P, Grabie N, Lichtman AH. Expansion of CD25+ Innate Lymphoid Cells Reduces Atherosclerosis. Arterioscler Thromb Vasc Biol. 2015 Dec; 35(12):2526-35. PMID: 26494229.
    Citations: 12     Fields:    Translation:AnimalsCells
  37. Wanke-Jellinek L, Keegan JW, Dolan JW, Lederer JA. Characterization of lung infection-induced TCR?d T cell phenotypes by CyTOF mass cytometry. J Leukoc Biol. 2016 Mar; 99(3):483-93. PMID: 26428679.
    Citations: 6     Fields:    Translation:AnimalsCells
  38. Lederer JA. Response to comment on "Radiation exposure induces inflammasome pathway activation in immune cells". J Immunol. 2015 Jun 01; 194(11):5039. PMID: 25980026.
    Citations:    Fields:    Translation:AnimalsCells
  39. Shay T, Lederer JA, Benoist C. Genomic responses to inflammation in mouse models mimic humans: we concur, apples to oranges comparisons won't do. Proc Natl Acad Sci U S A. 2015 Jan 27; 112(4):E346. PMID: 25540423.
    Citations: 20     Fields:    Translation:HumansAnimals
  40. Stoecklein VM, Osuka A, Ishikawa S, Lederer MR, Wanke-Jellinek L, Lederer JA. Radiation exposure induces inflammasome pathway activation in immune cells. J Immunol. 2015 Feb 01; 194(3):1178-89. PMID: 25539818.
    Citations: 39     Fields:    Translation:AnimalsCellsPHPublic Health
  41. Fellner J, Lederer J, Purgar A, Winterstetter A, Rechberger H, Winter F, Laner D. Evaluation of resource recovery from waste incineration residues--the case of zinc. Waste Manag. 2015 Mar; 37:95-103. PMID: 25458759.
    Citations: 3     Fields:    Translation:PHPublic Health
  42. Yamaguchi T, Calvacanti BM, Cruzat A, Qazi Y, Ishikawa S, Osuka A, Lederer J, Hamrah P. Correlation between human tear cytokine levels and cellular corneal changes in patients with bacterial keratitis by in vivo confocal microscopy. Invest Ophthalmol Vis Sci. 2014 Oct 16; 55(11):7457-66. PMID: 25324281.
    Citations: 19     Fields:    Translation:Humans
  43. Haspel JA, Chettimada S, Shaik RS, Chu JH, Raby BA, Cernadas M, Carey V, Process V, Hunninghake GM, Ifedigbo E, Lederer JA, Englert J, Pelton A, Coronata A, Fredenburgh LE, Choi AM. Circadian rhythm reprogramming during lung inflammation. Nat Commun. 2014 Sep 11; 5:4753. PMID: 25208554.
    Citations: 47     Fields:    Translation:AnimalsCells
  44. Osuchowski MF, Remick DG, Lederer JA, Lang CH, Aasen AO, Aibiki M, Azevedo LC, Bahrami S, Boros M, Cooney R, Cuzzocrea S, Jiang Y, Junger WG, Hirasawa H, Hotchkiss RS, Li XA, Radermacher P, Redl H, Salomao R, Soebandrio A, Thiemermann C, Vincent JL, Ward P, Yao YM, Yu HP, Zingarelli B, Chaudry IH. Abandon the mouse research ship? Not just yet! Shock. 2014 Jun; 41(6):463-75. PMID: 24569509.
    Citations: 77     Fields:    Translation:HumansAnimals
  45. Doyle TJ, Lee JS, Dellaripa PF, Lederer JA, Matteson EL, Fischer A, Ascherman DP, Glassberg MK, Ryu JH, Danoff SK, Brown KK, Collard HR, Rosas IO. A roadmap to promote clinical and translational research in rheumatoid arthritis-associated interstitial lung disease. Chest. 2014 Mar 01; 145(3):454-463. PMID: 24590021.
    Citations: 21     Fields:    Translation:Humans
  46. Osuka A, Ogura H, Ueyama M, Shimazu T, Lederer JA. Immune response to traumatic injury: harmony and discordance of immune system homeostasis. Acute Med Surg. 2014 Apr; 1(2):63-69. PMID: 29930824.
    Citations: 13     
  47. Hall SR, Tsoyi K, Ith B, Padera RF, Lederer JA, Wang Z, Liu X, Perrella MA. Mesenchymal stromal cells improve survival during sepsis in the absence of heme oxygenase-1: the importance of neutrophils. Stem Cells. 2013 Feb; 31(2):397-407. PMID: 23132816.
    Citations: 69     Fields:    Translation:AnimalsCells
  48. Tajima G, Delisle AJ, Hoang K, O'Leary FM, Ikeda K, Hanschen M, Stoecklein VM, Lederer JA. Immune system phenotyping of radiation and radiation combined injury in outbred mice. Radiat Res. 2013 Jan; 179(1):101-12. PMID: 23216446.
    Citations: 10     Fields:    Translation:AnimalsPHPublic Health
  49. Lederer JA. What's new in shock, November 2012? Shock. 2012 Nov; 38(5):447-9. PMID: 23076440.
    Citations:    Fields:    Translation:HumansAnimalsCells
  50. Osuka A, Hanschen M, Stoecklein V, Lederer J. Reply. Shock. 2012 Jun; 37(6):659-60. PMID: 22592637.
  51. Stoecklein VM, Osuka A, Lederer JA. Trauma equals danger--damage control by the immune system. J Leukoc Biol. 2012 Sep; 92(3):539-51. PMID: 22654121.
    Citations: 53     Fields:    Translation:HumansAnimals
  52. Lai PS, Fresco JM, Pinilla MA, Macias AA, Brown RD, Englert JA, Hofmann O, Lederer JA, Hide W, Christiani DC, Cernadas M, Baron RM. Chronic endotoxin exposure produces airflow obstruction and lung dendritic cell expansion. Am J Respir Cell Mol Biol. 2012 Aug; 47(2):209-17. PMID: 22517795.
    Citations: 10     Fields:    Translation:AnimalsCellsPHPublic Health
  53. Osuka A, Hanschen M, Stoecklein V, Lederer JA. A protective role for inflammasome activation following injury. Shock. 2012 Jan; 37(1):47-55. PMID: 21921832.
    Citations: 20     Fields:    Translation:AnimalsCells
  54. Byrne WL, Mills KH, Lederer JA, O'Sullivan GC. Targeting regulatory T cells in cancer. Cancer Res. 2011 Nov 15; 71(22):6915-20. PMID: 22068034.
    Citations: 76     Fields:    Translation:HumansCells
  55. Hanschen M, Tajima G, O'Leary F, Hoang K, Ikeda K, Lederer JA. Phospho-flow cytometry based analysis of differences in T cell receptor signaling between regulatory T cells and CD4+ T cells. J Immunol Methods. 2012 Feb 28; 376(1-2):1-12. PMID: 21945004.
    Citations: 7     Fields:    Translation:AnimalsCells
  56. O'Leary FM, Tajima G, Delisle AJ, Ikeda K, Dolan SM, Hanschen M, Mannick JA, Lederer JA. Injury-induced GR-1+ macrophage expansion and activation occurs independently of CD4 T-cell influence. Shock. 2011 Aug; 36(2):162-9. PMID: 21430603.
    Citations: 7     Fields:    Translation:AnimalsCells
  57. Bu DX, Tarrio M, Maganto-Garcia E, Stavrakis G, Tajima G, Lederer J, Jarolim P, Freeman GJ, Sharpe AH, Lichtman AH. Impairment of the programmed cell death-1 pathway increases atherosclerotic lesion development and inflammation. Arterioscler Thromb Vasc Biol. 2011 May; 31(5):1100-7. PMID: 21393583.
    Citations: 52     Fields:    Translation:AnimalsCells
  58. Hanschen M, Tajima G, O'Leary F, Ikeda K, Lederer JA. Injury induces early activation of T-cell receptor signaling pathways in CD4+ regulatory T cells. Shock. 2011 Mar; 35(3):252-7. PMID: 20720513.
    Citations: 14     Fields:    Translation:AnimalsCells
  59. MacConmara MP, Tajima G, O'Leary F, Delisle AJ, McKenna AM, Stallwood CG, Mannick JA, Lederer JA. Regulatory T cells suppress antigen-driven CD4 T cell reactivity following injury. J Leukoc Biol. 2011 Jan; 89(1):137-47. PMID: 20884652.
    Citations: 16     Fields:    Translation:AnimalsCells
  60. Zhou B, Xu W, Herndon D, Tompkins R, Davis R, Xiao W, Wong WH, Toner M, Warren HS, Schoenfeld DA, Rahme L, McDonald-Smith GP, Hayden D, Mason P, Fagan S, Yu YM, Cobb JP, Remick DG, Mannick JA, Lederer JA, Gamelli RL, Silver GM, West MA, Shapiro MB, Smith R, Camp DG, Qian W, Storey J, Mindrinos M, Tibshirani R, Lowry S, Calvano S, Chaudry I, West MA, Cohen M, Moore EE, Johnson J, Moldawer LL, Baker HV, Efron PA, Balis UG, Billiar TR, Ochoa JB, Sperry JL, Miller-Graziano CL, De AK, Bankey PE, Finnerty CC, Jeschke MG, Minei JP, Arnoldo BD, Hunt JL, Horton J, Cobb JP, Brownstein B, Freeman B, Maier RV, Nathens AB, Cuschieri J, Gibran N, Klein M, O'Keefe G. Analysis of factorial time-course microarrays with application to a clinical study of burn injury. Proc Natl Acad Sci U S A. 2010 Jun 01; 107(22):9923-8. PMID: 20479259.
    Citations: 34     Fields:    Translation:Humans
  61. Whelan MC, Casey G, MacConmara M, Lederer JA, Soden D, Collins JK, Tangney M, O'Sullivan GC. Effective immunotherapy of weakly immunogenic solid tumours using a combined immunogene therapy and regulatory T-cell inactivation. Cancer Gene Ther. 2010 Jul; 17(7):501-11. PMID: 20186173.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  62. Fujimi S, Lapchak PH, Zang Y, MacConmara MP, Maung AA, Delisle AJ, Mannick JA, Lederer JA. Murine dendritic cell antigen-presenting cell function is not altered by burn injury. J Leukoc Biol. 2009 May; 85(5):862-70. PMID: 19228816.
    Citations: 8     Fields:    Translation:AnimalsCells
  63. Maung AA, Fujimi S, MacConmara MP, Tajima G, McKenna AM, Delisle AJ, Stallwood C, Onderdonk AB, Mannick JA, Lederer JA. Injury enhances resistance to Escherichia coli infection by boosting innate immune system function. J Immunol. 2008 Feb 15; 180(4):2450-8. PMID: 18250454.
    Citations: 20     Fields:    Translation:Animals
  64. Kawasaki T, Choudhry MA, Schwacha MG, Fujimi S, Lederer JA, Bland KI, Chaudry IH. Trauma-hemorrhage inhibits splenic dendritic cell proinflammatory cytokine production via a mitogen-activated protein kinase process. . 2008 Mar; 294(3):C754-64. PMID: 18199702.
    Citations: 3     Translation:AnimalsCells
  65. Lederer JA, Brownstein BH, Lopez MC, Macmillan S, Delisle AJ, Macconmara MP, Choudhry MA, Xiao W, Lekousi S, Cobb JP, Baker HV, Mannick JA, Chaudry IH. Comparison of longitudinal leukocyte gene expression after burn injury or trauma-hemorrhage in mice. Physiol Genomics. 2008 Feb 19; 32(3):299-310. PMID: 17986522.
    Citations: 12     Fields:    Translation:AnimalsCells
  66. Gotsman I, Grabie N, Gupta R, Dacosta R, MacConmara M, Lederer J, Sukhova G, Witztum JL, Sharpe AH, Lichtman AH. Impaired regulatory T-cell response and enhanced atherosclerosis in the absence of inducible costimulatory molecule. Circulation. 2006 Nov 07; 114(19):2047-55. PMID: 17060381.
    Citations: 84     Fields:    Translation:AnimalsCells
  67. MacConmara MP, Maung AA, Fujimi S, McKenna AM, Delisle A, Lapchak PH, Rogers S, Lederer JA, Mannick JA. Increased CD4+ CD25+ T regulatory cell activity in trauma patients depresses protective Th1 immunity. Ann Surg. 2006 Oct; 244(4):514-23. PMID: 16998360.
    Citations: 49     Fields:    Translation:HumansCells
  68. Kawasaki T, Fujimi S, Lederer JA, Hubbard WJ, Choudhry MA, Schwacha MG, Bland KI, Chaudry IH. Trauma-hemorrhage induces depressed splenic dendritic cell functions in mice. J Immunol. 2006 Oct 01; 177(7):4514-20. PMID: 16982888.
    Citations: 39     Fields:    Translation:AnimalsCells
  69. Fujimi S, MacConmara MP, Maung AA, Zang Y, Mannick JA, Lederer JA, Lapchak PH. Platelet depletion in mice increases mortality after thermal injury. Blood. 2006 Jun 01; 107(11):4399-406. PMID: 16467203.
    Citations: 18     Fields:    Translation:AnimalsCells
  70. Purcell EM, Dolan SM, Kriynovich S, Mannick JA, Lederer JA. Burn injury induces an early activation response by lymph node CD4+ T cells. Shock. 2006 Feb; 25(2):135-40. PMID: 16525351.
    Citations: 17     Fields:    Translation:AnimalsCells
  71. Ni Choileain N, MacConmara M, Zang Y, Murphy TJ, Mannick JA, Lederer JA. Enhanced regulatory T cell activity is an element of the host response to injury. J Immunol. 2006 Jan 01; 176(1):225-36. PMID: 16365414.
    Citations: 43     Fields:    Translation:AnimalsCells
  72. Brownstein BH, Logvinenko T, Lederer JA, Cobb JP, Hubbard WJ, Chaudry IH, Remick DG, Baker HV, Xiao W, Mannick JA. Commonality and differences in leukocyte gene expression patterns among three models of inflammation and injury. Physiol Genomics. 2006 Feb 14; 24(3):298-309. PMID: 16478828.
    Citations: 17     Fields:    Translation:AnimalsCells
  73. MacConmara M, Lederer JA. B cells. Crit Care Med. 2005 Dec; 33(12 Suppl):S514-6. PMID: 16340437.
    Citations:    Fields:    Translation:HumansAnimalsCells
  74. Maung AA, Fujimi S, Miller ML, MacConmara MP, Mannick JA, Lederer JA. Enhanced TLR4 reactivity following injury is mediated by increased p38 activation. J Leukoc Biol. 2005 Aug; 78(2):565-73. PMID: 15857937.
    Citations: 36     Fields:    Translation:AnimalsCells
  75. Lederer JA. Does nitric oxide control the counter-inflammatory response in endotoxic shock? Crit Care Med. 2005 Apr; 33(4):896-8. PMID: 15818123.
    Citations: 1     Fields:    Translation:AnimalsCells
  76. Cobb JP, Mindrinos MN, Miller-Graziano C, Calvano SE, Baker HV, Xiao W, Laudanski K, Brownstein BH, Elson CM, Hayden DL, Herndon DN, Lowry SF, Maier RV, Schoenfeld DA, Moldawer LL, Davis RW, Tompkins RG, Baker HV, Bankey P, Billiar T, Brownstein BH, Calvano SE, Camp D, Chaudry I, Cobb JP, Davis RW, Elson CM, Freeman B, Gamelli R, Gibran N, Harbrecht B, Hayden DL, Heagy W, Heimbach D, Herndon DN, Horton J, Hunt J, Laudanski K, Lederer J, Lowry SF, Maier RV, Mannick J, McKinley B, Miller-Graziano C, Mindrinos MN, Minei J, Moldawer LL, Moore E, Moore F, Munford R, Nathens A, O'keefe G, Purdue G, Rahme L, Remick D, Sailors M, Schoenfeld DA, Shapiro M, Silver G, Smith R, Stephanopoulos G, Stormo G, Tompkins RG, Toner M, Warren S, West M, Wolfe S, Xiao W, Young V. Application of genome-wide expression analysis to human health and disease. Proc Natl Acad Sci U S A. 2005 Mar 29; 102(13):4801-6. PMID: 15781863.
    Citations: 108     Fields:    Translation:HumansCells
  77. Murphy TJ, Ni Choileain N, Zang Y, Mannick JA, Lederer JA. CD4+CD25+ regulatory T cells control innate immune reactivity after injury. J Immunol. 2005 Mar 01; 174(5):2957-63. PMID: 15728508.
    Citations: 71     Fields:    Translation:AnimalsCells
  78. Murphy TJ, Paterson HM, Kriynovich S, Zang Y, Kurt-Jones EA, Mannick JA, Lederer JA. Linking the "two-hit" response following injury to enhanced TLR4 reactivity. J Leukoc Biol. 2005 Jan; 77(1):16-23. PMID: 15496450.
    Citations: 30     Fields:    Translation:AnimalsCells
  79. Zang Y, Dolan SM, Ni Choileain N, Kriynovich SJ, Murphy TJ, Sayles P, Mannick JA, Lederer JA. Burn injury initiates a shift in superantigen-induced T cell responses and host survival. J Immunol. 2004 Apr 15; 172(8):4883-92. PMID: 15067067.
    Citations: 9     Fields:    Translation:AnimalsCells
  80. Guo Z, Kavanagh E, Zang Y, Dolan SM, Kriynovich SJ, Mannick JA, Lederer JA. Burn injury promotes antigen-driven Th2-type responses in vivo. J Immunol. 2003 Oct 15; 171(8):3983-90. PMID: 14530317.
    Citations: 22     Fields:    Translation:AnimalsCells
  81. Murphy TJ, Paterson HM, Mannick JA, Lederer JA. Injury, sepsis, and the regulation of Toll-like receptor responses. J Leukoc Biol. 2004 Mar; 75(3):400-7. PMID: 14557385.
    Citations: 56     Fields:    Translation:HumansAnimals
  82. Murphy T, Paterson H, Rogers S, Mannick JA, Lederer JA. Use of intracellular cytokine staining and bacterial superantigen to document suppression of the adaptive immune system in injured patients. Ann Surg. 2003 Sep; 238(3):401-10; discussion 410-1. PMID: 14501506.
    Citations: 14     Fields:    Translation:HumansCells
  83. Shelley O, Murphy T, Paterson H, Mannick JA, Lederer JA. Interaction between the innate and adaptive immune systems is required to survive sepsis and control inflammation after injury. Shock. 2003 Aug; 20(2):123-9. PMID: 12865655.
    Citations: 35     Fields:    Translation:AnimalsCells
  84. Paterson HM, Murphy TJ, Purcell EJ, Shelley O, Kriynovich SJ, Lien E, Mannick JA, Lederer JA. Injury primes the innate immune system for enhanced Toll-like receptor reactivity. J Immunol. 2003 Aug 01; 171(3):1473-83. PMID: 12874240.
    Citations: 72     Fields:    Translation:AnimalsCells
  85. Shelley O, Murphy T, Lederer JA, Mannick JA, Rodrick ML. Mast cells and resistance to peritoneal sepsis after burn injury. Shock. 2003 Jun; 19(6):513-8. PMID: 12785005.
    Citations: 3     Fields:    Translation:AnimalsCells
  86. Mueller TF, Ma C, Lederer JA, Perkins DL. Differentiation of stress, metabolism, communication, and defense responses following transplantation. J Leukoc Biol. 2003 Mar; 73(3):379-90. PMID: 12629152.
    Citations: 3     Fields:    Translation:Animals
  87. Mannick JA, Rodrick ML, Lederer JA. The immunologic response to injury. J Am Coll Surg. 2001 Sep; 193(3):237-44. PMID: 11548792.
    Citations: 56     Fields:    Translation:HumansCells
  88. O'Suilleabhain CB, Kim S, Rodrick MR, Mannick JA, Lederer JA. Injury induces alterations in T-cell NFkappaB and AP-1 activation. Shock. 2001 Jun; 15(6):432-7. PMID: 11386614.
    Citations: 8     Fields:    Translation:AnimalsCells
  89. Kell MR, Shelley O, Mannick JA, Guo Z, Lederer JA. A central role for CD95 (Fas) in T-cell reactivity after injury. Surgery. 2000 Aug; 128(2):159-64. PMID: 10922986.
    Citations: 2     Fields:    Translation:AnimalsCells
  90. Göebel A, Kavanagh E, Lyons A, Saporoschetz IB, Soberg C, Lederer JA, Mannick JA, Rodrick ML. Injury induces deficient interleukin-12 production, but interleukin-12 therapy after injury restores resistance to infection. Ann Surg. 2000 Feb; 231(2):253-61. PMID: 10674618.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  91. Lyons A, Goebel A, Mannick JA, Lederer JA. Protective effects of early interleukin 10 antagonism on injury-induced immune dysfunction. Arch Surg. 1999 Dec; 134(12):1317-23; discussion 1324. PMID: 10593329.
    Citations: 21     Fields:    Translation:AnimalsCells
  92. Kell MR, Kavanaugh EG, Goebel A, Soberg CC, Lederer JA. Injury primes the immune system for an enhanced and lethal T-cell response against bacterial superantigen. Shock. 1999 Aug; 12(2):139-44. PMID: 10446895.
    Citations: 4     Fields:    Translation:AnimalsCells
  93. Kavanagh EK, Kell MR, Goebel A, Soberg CC, Mannick JA, Lederer JA. Interleukin 10 is not essential for survival or for modulating T-cell function after injury. Surgery. 1999 Aug; 126(2):456-62. PMID: 10455921.
    Citations:    Fields:    Translation:AnimalsCells
  94. Sadanaga N, Nagoshi M, Lederer JA, Joo HG, Eberlein TJ, Goedegebuure PS. Local secretion of IFN-gamma induces an antitumor response: comparison between T cells plus IL-2 and IFN-gamma transfected tumor cells. J Immunother. 1999 Jul; 22(4):315-23. PMID: 10404433.
    Citations: 3     Fields:    Translation:AnimalsCells
  95. Kelly JL, O'Suilleabhain CB, Soberg CC, Mannick JA, Lederer JA. Severe injury triggers antigen-specific T-helper cell dysfunction. Shock. 1999 Jul; 12(1):39-45. PMID: 10468050.
    Citations: 18     Fields:    Translation:AnimalsCellsPHPublic Health
  96. Lederer JA, Rodrick ML, Mannick JA. The effects of injury on the adaptive immune response. Shock. 1999 Mar; 11(3):153-9. PMID: 10188766.
    Citations: 88     Fields:    Translation:HumansAnimalsCells
  97. Mark DA, Donovan CE, De Sanctis GT, Krinzman SJ, Kobzik L, Linsley PS, Sayegh MH, Lederer J, Perkins DL, Finn PW. Both CD80 and CD86 co-stimulatory molecules regulate allergic pulmonary inflammation. Int Immunol. 1998 Nov; 10(11):1647-55. PMID: 9846693.
    Citations: 9     Fields:    Translation:AnimalsCells
  98. Kavanagh EG, Kelly JL, Lyons A, Soberg CC, Mannick JA, Lederer JA. Burn injury primes naive CD4+ T cells for an augmented T-helper 1 response. Surgery. 1998 Aug; 124(2):269-76; discussion 276-7. PMID: 9706148.
    Citations: 5     Fields:    Translation:AnimalsCells
  99. Behar SM, Roy C, Lederer J, Fraser P, Brenner MB. Clonally expanded Valpha12+ (AV12S1),CD8+ T cells from a patient with rheumatoid arthritis are autoreactive. Arthritis Rheum. 1998 Mar; 41(3):498-506. PMID: 9506578.
    Citations: 1     Fields:    Translation:HumansCells
  100. Lyons A, Kelly JL, Rodrick ML, Mannick JA, Lederer JA. Major injury induces increased production of interleukin-10 by cells of the immune system with a negative impact on resistance to infection. Ann Surg. 1997 Oct; 226(4):450-8; discussion 458-60. PMID: 9351713.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  101. Kelly JL, Lyons A, Soberg CC, Mannick JA, Lederer JA. Anti-interleukin-10 antibody restores burn-induced defects in T-cell function. Surgery. 1997 Aug; 122(2):146-52. PMID: 9288117.
    Citations: 19     Fields:    Translation:AnimalsCells
  102. Borriello F, Lederer J, Scott S, Sharpe AH. MRC OX-2 defines a novel T cell costimulatory pathway. J Immunol. 1997 May 15; 158(10):4548-54. PMID: 9144466.
    Citations: 9     Fields:    Translation:AnimalsCells
  103. O'Suilleabhain C, O'Sullivan ST, Kelly JL, Lederer J, Mannick JA, Rodrick ML. Interleukin-12 treatment restores normal resistance to bacterial challenge after burn injury. Surgery. 1996 Aug; 120(2):290-6. PMID: 8751595.
    Citations: 26     Fields:    Translation:AnimalsCells
  104. Lederer JA, Perez VL, DesRoches L, Kim SM, Abbas AK, Lichtman AH. Cytokine transcriptional events during helper T cell subset differentiation. J Exp Med. 1996 Aug 01; 184(2):397-406. PMID: 8760793.
    Citations: 29     Fields:    Translation:AnimalsCells
  105. Lederer JA, Liou JS, Kim S, Rice N, Lichtman AH. Regulation of NF-kappa B activation in T helper 1 and T helper 2 cells. J Immunol. 1996 Jan 01; 156(1):56-63. PMID: 8598494.
    Citations: 8     Fields:    Translation:AnimalsCells
  106. Borriello F, Lederer J. Construction of quantitative RT-PCR MIMICs. Biotechniques. 1995 Oct; 19(4):580-2, 584. PMID: 8777050.
    Citations: 3     Fields:    Translation:Cells
  107. O'Sullivan ST, Lederer JA, Horgan AF, Chin DH, Mannick JA, Rodrick ML. Major injury leads to predominance of the T helper-2 lymphocyte phenotype and diminished interleukin-12 production associated with decreased resistance to infection. Ann Surg. 1995 Oct; 222(4):482-90; discussion 490-2. PMID: 7574928.
    Citations: 104     Fields:    Translation:HumansAnimalsCells
  108. Perez VL, Lederer JA, Carniel E, Lichtman A, Abbas AK. The role of IL12 in helper T-cell differentiation. Res Immunol. 1995 Sep-Oct; 146(7-8):477-80. PMID: 8839149.
    Citations: 2     Fields:    Translation:AnimalsCells
  109. Briscoe DM, DesRoches LE, Kiely JM, Lederer JA, Lichtman AH. Antigen-dependent activation of T helper cell subsets by endothelium. Transplantation. 1995 Jun 15; 59(11):1638-41. PMID: 7778184.
    Citations: 3     Fields:    Translation:AnimalsCells
  110. Perez VL, Lederer JA, Lichtman AH, Abbas AK. Stability of Th1 and Th2 populations. Int Immunol. 1995 May; 7(5):869-75. PMID: 7547713.
    Citations: 37     Fields:    Translation:AnimalsCells
  111. Young HA, Ghosh P, Ye J, Lederer J, Lichtman A, Gerard JR, Penix L, Wilson CB, Melvin AJ, McGurn ME, et al. Differentiation of the T helper phenotypes by analysis of the methylation state of the IFN-gamma gene. J Immunol. 1994 Oct 15; 153(8):3603-10. PMID: 7523497.
    Citations: 53     Fields:    Translation:AnimalsCells
  112. Lederer JA, Czuprynski CJ. Species-specific binding of IL-1, but not the IL-1 receptor antagonist, by fibroblasts. Cytokine. 1994 Mar; 6(2):154-61. PMID: 8031998.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  113. Lederer JA, Liou JS, Todd MD, Glimcher LH, Lichtman AH. Regulation of cytokine gene expression in T helper cell subsets. J Immunol. 1994 Jan 01; 152(1):77-86. PMID: 8254209.
    Citations: 15     Fields:    Translation:AnimalsCells
  114. St Louis JD, Lederer JA, Lichtman AH. Costimulator deficient antigen presentation by an endothelial cell line induces a nonproliferative T cell activation response without anergy. J Exp Med. 1993 Nov 01; 178(5):1597-605. PMID: 7693852.
    Citations: 13     Fields:    Translation:AnimalsCells
  115. Todd MD, Grusby MJ, Lederer JA, Lacy E, Lichtman AH, Glimcher LH. Transcription of the interleukin 4 gene is regulated by multiple promoter elements. J Exp Med. 1993 Jun 01; 177(6):1663-74. PMID: 8496684.
    Citations: 21     Fields:    Translation:AnimalsCells
  116. Nishri Z, Zalewski SE, Glücks L, Avni R, Lederer J, Mates A. Prevalence of antibodies to Toxoplasma gondii in the Tel-Mond area. Isr J Med Sci. 1993 Jan; 29(1):30-2. PMID: 8454443.
    Citations: 1     Fields:    Translation:HumansAnimals
  117. Kenefick KB, Lederer JA, Schell RF, Czuprynski CJ. Borrelia burgdorferi stimulates release of interleukin-1 activity from bovine peripheral blood monocytes. Infect Immun. 1992 Sep; 60(9):3630-4. PMID: 1500171.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  118. Lederer JA, Czuprynski CJ. Characterization and identification of interleukin 1 receptors on bovine neutrophils. J Leukoc Biol. 1992 Jun; 51(6):586-90. PMID: 1535356.
    Citations:    Fields:    Translation:AnimalsCells
  119. Lederer JA, Czuprynski CJ. Species preference of bovine thymocytes and fibroblasts for bovine interleukin 1. Vet Immunol Immunopathol. 1989 Dec; 23(3-4):213-22. PMID: 2629193.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  120. Lederer JA, Czuprynski CJ. Production and purification of bovine monocyte-derived interleukin 1. Vet Immunol Immunopathol. 1989 Dec; 23(3-4):201-11. PMID: 2629192.
    Citations: 4     Fields:    Translation:AnimalsCells
  121. Lederer J. [The problem of the prevention of selenium deficiency in Belgium]. Arch Belg. 1989; 47(7-8):291-311. PMID: 2486231.
    Citations:    Fields:    Translation:HumansAnimals
  122. Lederer JA, Brown JF, Czuprynski CJ. "Haemophilus somnus," a facultative intracellular pathogen of bovine mononuclear phagocytes. Infect Immun. 1987 Feb; 55(2):381-7. PMID: 3026966.
    Citations: 16     Fields:    Translation:AnimalsCells
  123. Lederer J. [Incidence of diabetes in ethnic groups]. Probl Actuels Endocrinol Nutr. 1975; 19:301-10. PMID: 1233500.
    Citations:    Fields:    Translation:Humans
  124. LEDERER J. A new development in aids for sub-normal vision. Nature. 1954 Nov 20; 174(4438):977-8. PMID: 13214058.
    Citations: 1     Fields:    Translation:Humans
  125. LEDERER J, DAVIS R. [Pathology of the thyroid-adrenocortical system]. Schweiz Med Wochenschr. 1951 Oct 13; 81(41):1020-3. PMID: 14876420.
    Citations: 1     Fields:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.