Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Bo Zhao, Ph.D.

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Institution
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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. 5R01AI123420 (ZHAO, BO) Mar 1, 2016 - Mar 31, 2026
    NIH/NIAID
    TARGETING EPSTEIN-BARR VIRUS SUPER-ENHANCERS
    Role: Principal Investigator
  2. R01CA170023 (ZHAO, BO) Mar 15, 2013 - Feb 28, 2018
    NIH/NCI
    ROLES OF EPSTEIN-BARR VIRUS NUCLEAR ANTIGENS 2 AND LP IN B CELL PROLIFERATION
    Role: Principal Investigator
  3. 5R01CA047006-31 (ZHAO, BO) Jun 1, 1987 - Jul 31, 2022
    NIH
    Epstein-Barr Virus Nuclear Protein B Cell Growth Transformation
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Yan B, Wang C, Chakravorty S, Zhang Z, Kadadi SD, Zhuang Y, Sirit I, Hu Y, Jung M, Sahoo SS, Wang L, Shao K, Anderson NL, Trujillo-Ochoa JL, Briggs SD, Liu X, Olson MR, Afzali B, Zhao B, Kazemian M. A comprehensive single cell data analysis of lymphoblastoid cells reveals the role of super-enhancers in maintaining EBV latency. J Med Virol. 2023 01; 95(1):e28362. PMID: 36453088.
    Citations: 1     Fields:    Translation:HumansCells
  2. Ding W, Wang C, Narita Y, Wang H, Leong MML, Huang A, Liao Y, Liu X, Okuno Y, Kimura H, Gewurz B, Teng M, Jin S, Sato Y, Zhao B. The Epstein-Barr Virus Enhancer Interaction Landscapes in Virus-Associated Cancer Cell Lines. J Virol. 2022 09 28; 96(18):e0073922. PMID: 36094314; PMCID: PMC9517713.
    Citations:    Fields:    Translation:HumansCells
  3. Liu X, Zhao B, Shaw TI, Fridley BL, Duckett DR, Tan AC, Teng M. Summarizing internal dynamics boosts differential analysis and functional interpretation of super enhancers. Nucleic Acids Res. 2022 04 08; 50(6):3115-3127. PMID: 35234924; PMCID: PMC8989535.
    Citations:    Fields:    Translation:Cells
  4. Hong T, Parameswaran S, Donmez OA, Miller D, Forney C, Lape M, Saint Just Ribeiro M, Liang J, Edsall LE, Magnusen AF, Miller W, Chepelev I, Harley JB, Zhao B, Kottyan LC, Weirauch MT. Epstein-Barr virus nuclear antigen 2 extensively rewires the human chromatin landscape at autoimmune risk loci. Genome Res. 2021 Nov 19. PMID: 34799401; PMCID: PMC8647835.
    Citations: 4     Fields:    
  5. Liang JH, Wang C, Yiu SPT, Zhao B, Guo R, Gewurz BE. Epstein-Barr Virus Induced Cytidine Metabolism Roles in Transformed B-Cell Growth and Survival. mBio. 2021 08 31; 12(4):e0153021. PMID: 34281398.
    Citations: 4     Fields:    Translation:HumansCells
  6. Xia TL, Li X, Wang X, Zhu YJ, Zhang H, Cheng W, Chen ML, Ye Y, Li Y, Zhang A, Dai DL, Zhu QY, Yuan L, Zheng J, Huang H, Chen SQ, Xiao ZW, Wang HB, Roy G, Zhong Q, Lin D, Zeng YX, Wang J, Zhao B, Gewurz BE, Chen J, Zuo Z, Zeng MS. N(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay. EMBO Rep. 2021 04 07; 22(4):e50128. PMID: 33605073.
    Citations: 13     Fields:    Translation:HumansCells
  7. Wang C, Zhang L, Ke L, Ding W, Jiang S, Li D, Narita Y, Hou I, Liang J, Li S, Xiao H, Gottwein E, Kaye KM, Teng M, Zhao B. Primary effusion lymphoma enhancer connectome links super-enhancers to dependency factors. Nat Commun. 2020 12 09; 11(1):6318. PMID: 33298918; PMCID: PMC7726151.
    Citations: 7     Fields:    Translation:HumansCells
  8. Wang L, Laing J, Yan B, Zhou H, Ke L, Wang C, Narita Y, Zhang Z, Olson MR, Afzali B, Zhao B, Kazemian M. Epstein-Barr Virus Episome Physically Interacts with Active Regions of the Host Genome in Lymphoblastoid Cells. J Virol. 2020 11 23; 94(24). PMID: 32999023.
    Citations: 5     Fields:    Translation:HumansCells
  9. Zhang Y, Jiang C, Trudeau SJ, Narita Y, Zhao B, Teng M, Guo R, Gewurz BE. Histone Loaders CAF1 and HIRA Restrict Epstein-Barr Virus B-Cell Lytic Reactivation. mBio. 2020 10 27; 11(5). PMID: 33109754.
    Citations: 9     Fields:    Translation:HumansCells
  10. Jin S, Li R, Chen MY, Yu C, Tang LQ, Liu YM, Li JP, Liu YN, Luo YL, Zhao Y, Zhang Y, Xia TL, Liu SX, Liu Q, Wang GN, You R, Peng JY, Li J, Han F, Wang J, Chen QY, Zhang L, Mai HQ, Gewurz BE, Zhao B, Young LS, Zhong Q, Bai F, Zeng MS. Single-cell transcriptomic analysis defines the interplay between tumor cells, viral infection, and the microenvironment in nasopharyngeal carcinoma. Cell Res. 2020 11; 30(11):950-965. PMID: 32901110; PMCID: PMC7784966.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  11. Guo R, Zhang Y, Teng M, Jiang C, Schineller M, Zhao B, Doench JG, O'Reilly RJ, Cesarman E, Giulino-Roth L, Gewurz BE. DNA methylation enzymes and PRC1 restrict B-cell Epstein-Barr virus oncoprotein expression. Nat Microbiol. 2020 08; 5(8):1051-1063. PMID: 32424339; PMCID: PMC7462085.
    Citations: 11     Fields:    Translation:HumansCells
  12. Guo R, Jiang C, Zhang Y, Govande A, Trudeau SJ, Chen F, Fry CJ, Puri R, Wolinsky E, Schineller M, Frost TC, Gebre M, Zhao B, Giulino-Roth L, Doench JG, Teng M, Gewurz BE. MYC Controls the Epstein-Barr Virus Lytic Switch. Mol Cell. 2020 05 21; 78(4):653-669.e8. PMID: 32315601.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  13. Wang LW, Wang Z, Ersing I, Nobre L, Guo R, Jiang S, Trudeau S, Zhao B, Weekes MP, Gewurz BE. Epstein-Barr virus subverts mevalonate and fatty acid pathways to promote infected B-cell proliferation and survival. PLoS Pathog. 2019 09; 15(9):e1008030. PMID: 31518366.
    Citations: 19     Fields:    Translation:HumansCells
  14. Chakravorty S, Yan B, Wang C, Wang L, Quaid JT, Lin CF, Briggs SD, Majumder J, Canaria DA, Chauss D, Chopra G, Olson MR, Zhao B, Afzali B, Kazemian M. Integrated Pan-Cancer Map of EBV-Associated Neoplasms Reveals Functional Host-Virus Interactions. Cancer Res. 2019 12 01; 79(23):6010-6023. PMID: 31481499.
    Citations: 23     Fields:    Translation:HumansCells
  15. Wang C, Jiang S, Zhang L, Li D, Liang J, Narita Y, Hou I, Zhong Q, Gewurz BE, Teng M, Zhao B. TAF Family Proteins and MEF2C Are Essential for Epstein-Barr Virus Super-Enhancer Activity. J Virol. 2019 08 15; 93(16). PMID: 31167905; PMCID: PMC6675876.
    Citations: 6     Fields:    Translation:HumansCells
  16. Jiang C, Trudeau SJ, Cheong TC, Guo R, Teng M, Wang LW, Wang Z, Pighi C, Gautier-Courteille C, Ma Y, Jiang S, Wang C, Zhao B, Paillard L, Doench JG, Chiarle R, Gewurz BE. CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation. Cell Rep. 2019 07 30; 28(5):1307-1322.e8. PMID: 31365872; PMCID: PMC6684324.
    Citations: 4     Fields:    Translation:HumansCells
  17. Wang C, Li D, Zhang L, Jiang S, Liang J, Narita Y, Hou I, Zhong Q, Zheng Z, Xiao H, Gewurz BE, Teng M, Zhao B. RNA Sequencing Analyses of Gene Expression during Epstein-Barr Virus Infection of Primary B Lymphocytes. J Virol. 2019 07 01; 93(13). PMID: 31019051; PMCID: PMC6580941.
    Citations: 25     Fields:    Translation:HumansCells
  18. Wang C, Jiang S, Ke L, Zhang L, Li D, Liang J, Narita Y, Hou I, Chen CH, Wang L, Zhong Q, Ling Y, Lv X, Xiang Y, Guo X, Teng M, Tsao SW, Gewurz BE, Zeng MS, Zhao B. Genome-wide CRISPR-based gene knockout screens reveal cellular factors and pathways essential for nasopharyngeal carcinoma. J Biol Chem. 2019 06 21; 294(25):9734-9745. PMID: 31073033; PMCID: PMC6597810.
    Citations: 2     Fields:    Translation:HumansCells
  19. Wang C, Zhou H, Xue Y, Liang J, Narita Y, Gerdt C, Zheng AY, Jiang R, Trudeau S, Peng CW, Gewurz BE, Zhao B. Epstein-Barr Virus Nuclear Antigen Leader Protein Coactivates EP300. J Virol. 2018 05 01; 92(9). PMID: 29467311; PMCID: PMC5899200.
    Citations: 5     Fields:    Translation:HumansCells
  20. Wang LW, Trudeau SJ, Wang C, Gerdt C, Jiang S, Zhao B, Gewurz BE. Modulating Gene Expression in Epstein-Barr Virus (EBV)-Positive B Cell Lines with CRISPRa and CRISPRi. Curr Protoc Mol Biol. 2018 01 16; 121:31.13.1-31.13.18. PMID: 29337370.
    Citations: 2     Fields:    Translation:HumansCells
  21. Jiang S, Wang LW, Walsh MJ, Trudeau SJ, Gerdt C, Zhao B, Gewurz BE. CRISPR/Cas9-Mediated Genome Editing in Epstein-Barr Virus-Transformed Lymphoblastoid B-Cell Lines. Curr Protoc Mol Biol. 2018 01 16; 121:31.12.1-31.12.23. PMID: 29337376.
    Citations: 10     Fields:    Translation:HumansCells
  22. Zhang H, Li Y, Wang HB, Zhang A, Chen ML, Fang ZX, Dong XD, Li SB, Du Y, Xiong D, He JY, Li MZ, Liu YM, Zhou AJ, Zhong Q, Zeng YX, Kieff E, Zhang Z, Gewurz BE, Zhao B, Zeng MS. Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry. Nat Microbiol. 2018 02; 3(2):1-8. PMID: 29292383.
    Citations: 90     Fields:    Translation:HumansAnimalsCells
  23. Jiang S, Zhou H, Liang J, Gerdt C, Wang C, Ke L, Schmidt SCS, Narita Y, Ma Y, Wang S, Colson T, Gewurz B, Li G, Kieff E, Zhao B. The Epstein-Barr Virus Regulome in Lymphoblastoid Cells. Cell Host Microbe. 2017 Oct 11; 22(4):561-573.e4. PMID: 29024646; PMCID: PMC5662195.
    Citations: 47     Fields:    Translation:HumansCells
  24. Ke L, Zhou H, Wang C, Xiong G, Xiang Y, Ling Y, Khabir A, Tsao GS, Zeng Y, Zeng M, Busson P, Kieff E, Guo X, Zhao B. Nasopharyngeal carcinoma super-enhancer-driven ETV6 correlates with prognosis. Proc Natl Acad Sci U S A. 2017 09 05; 114(36):9683-9688. PMID: 28831010; PMCID: PMC5594663.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  25. Ma Y, Walsh MJ, Bernhardt K, Ashbaugh CW, Trudeau SJ, Ashbaugh IY, Jiang S, Jiang C, Zhao B, Root DE, Doench JG, Gewurz BE. CRISPR/Cas9 Screens Reveal Epstein-Barr Virus-Transformed B Cell Host Dependency Factors. Cell Host Microbe. 2017 May 10; 21(5):580-591.e7. PMID: 28494239; PMCID: PMC8938989.
    Citations: 64     Fields:    Translation:HumansCells
  26. Minamitani T, Ma Y, Zhou H, Kida H, Tsai CY, Obana M, Okuzaki D, Fujio Y, Kumanogoh A, Zhao B, Kikutani H, Kieff E, Gewurz BE, Yasui T. Mouse model of Epstein-Barr virus LMP1- and LMP2A-driven germinal center B-cell lymphoproliferative disease. Proc Natl Acad Sci U S A. 2017 05 02; 114(18):4751-4756. PMID: 28351978; PMCID: PMC5422827.
    Citations: 22     Fields:    Translation:AnimalsCells
  27. Liang J, Zhou H, Gerdt C, Tan M, Colson T, Kaye KM, Kieff E, Zhao B. Epstein-Barr virus super-enhancer eRNAs are essential for MYC oncogene expression and lymphoblast proliferation. Proc Natl Acad Sci U S A. 2016 12 06; 113(49):14121-14126. PMID: 27864512; PMCID: PMC5150416.
    Citations: 45     Fields:    Translation:HumansCells
  28. Hu L, Lin Z, Wu Y, Dong J, Zhao B, Cheng Y, Huang P, Xu L, Xia T, Xiong D, Wang H, Li M, Guo L, Kieff E, Zeng Y, Zhong Q, Zeng M. Comprehensive profiling of EBV gene expression in nasopharyngeal carcinoma through paired-end transcriptome sequencing. Front Med. 2016 Mar; 10(1):61-75. PMID: 26969667.
    Citations: 29     Fields:    Translation:HumansCells
  29. Wang A, Welch R, Zhao B, Ta T, Keles S, Johannsen E. Epstein-Barr Virus Nuclear Antigen 3 (EBNA3) Proteins Regulate EBNA2 Binding to Distinct RBPJ Genomic Sites. J Virol. 2015 Dec 30; 90(6):2906-19. PMID: 26719268; PMCID: PMC4810642.
    Citations: 26     Fields:    Translation:HumansCells
  30. Hunter JE, Butterworth JA, Zhao B, Sellier H, Campbell KJ, Thomas HD, Bacon CM, Cockell SJ, Gewurz BE, Perkins ND. The NF-?B subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma. Oncogene. 2016 06 30; 35(26):3476-84. PMID: 26522720; PMCID: PMC4853301.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  31. Xiong D, Du Y, Wang HB, Zhao B, Zhang H, Li Y, Hu LJ, Cao JY, Zhong Q, Liu WL, Li MZ, Zhu XF, Tsao SW, Hutt-Fletcher LM, Song E, Zeng YX, Kieff E, Zeng MS. Nonmuscle myosin heavy chain IIA mediates Epstein-Barr virus infection of nasopharyngeal epithelial cells. Proc Natl Acad Sci U S A. 2015 Sep 01; 112(35):11036-41. PMID: 26290577; PMCID: PMC4568263.
    Citations: 40     Fields:    Translation:HumansCells
  32. Wang HB, Zhang H, Zhang JP, Li Y, Zhao B, Feng GK, Du Y, Xiong D, Zhong Q, Liu WL, Du H, Li MZ, Huang WL, Tsao SW, Hutt-Fletcher L, Zeng YX, Kieff E, Zeng MS. Neuropilin 1 is an entry factor that promotes EBV infection of nasopharyngeal epithelial cells. Nat Commun. 2015 Feb 11; 6:6240. PMID: 25670642.
    Citations: 80     Fields:    Translation:HumansCells
  33. Zhou H, Schmidt SC, Jiang S, Willox B, Bernhardt K, Liang J, Johannsen EC, Kharchenko P, Gewurz BE, Kieff E, Zhao B. Epstein-Barr virus oncoprotein super-enhancers control B cell growth. Cell Host Microbe. 2015 Feb 11; 17(2):205-16. PMID: 25639793; PMCID: PMC4539236.
    Citations: 83     Fields:    Translation:Cells
  34. Schmidt SC, Jiang S, Zhou H, Willox B, Holthaus AM, Kharchenko PV, Johannsen EC, Kieff E, Zhao B. Epstein-Barr virus nuclear antigen 3A partially coincides with EBNA3C genome-wide and is tethered to DNA through BATF complexes. Proc Natl Acad Sci U S A. 2015 Jan 13; 112(2):554-9. PMID: 25540416; PMCID: PMC4299249.
    Citations: 30     Fields:    Translation:HumansCells
  35. Iannetti A, Ledoux AC, Tudhope SJ, Sellier H, Zhao B, Mowla S, Moore A, Hummerich H, Gewurz BE, Cockell SJ, Jat PS, Willmore E, Perkins ND. Regulation of p53 and Rb links the alternative NF-?B pathway to EZH2 expression and cell senescence. PLoS Genet. 2014 Sep; 10(9):e1004642. PMID: 25255445; PMCID: PMC4177746.
    Citations: 48     Fields:    Translation:HumansCells
  36. Zhao B, Barrera LA, Ersing I, Willox B, Schmidt SC, Greenfeld H, Zhou H, Mollo SB, Shi TT, Takasaki K, Jiang S, Cahir-McFarland E, Kellis M, Bulyk ML, Kieff E, Gewurz BE. The NF-?B genomic landscape in lymphoblastoid B cells. Cell Rep. 2014 Sep 11; 8(5):1595-606. PMID: 25159142.
    Citations: 87     Fields:    Translation:HumansCells
  37. Lee EK, Kim SY, Noh KW, Joo EH, Zhao B, Kieff E, Kang MS. Small molecule inhibition of Epstein-Barr virus nuclear antigen-1 DNA binding activity interferes with replication and persistence of the viral genome. Antiviral Res. 2014 Apr; 104:73-83. PMID: 24486954.
    Citations: 10     Fields:    Translation:HumansCells
  38. Jiang S, Willox B, Zhou H, Holthaus AM, Wang A, Shi TT, Maruo S, Kharchenko PV, Johannsen EC, Kieff E, Zhao B. Epstein-Barr virus nuclear antigen 3C binds to BATF/IRF4 or SPI1/IRF4 composite sites and recruits Sin3A to repress CDKN2A. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):421-6. PMID: 24344258.
    Citations: 51     Fields:    Translation:HumansCells
  39. Chen YL, Liu CD, Cheng CP, Zhao B, Hsu HJ, Shen CL, Chiu SJ, Kieff E, Peng CW. Nucleolin is important for Epstein-Barr virus nuclear antigen 1-mediated episome binding, maintenance, and transcription. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):243-8. PMID: 24344309.
    Citations: 19     Fields:    Translation:HumansCells
  40. Portal D, Zhou H, Zhao B, Kharchenko PV, Lowry E, Wong L, Quackenbush J, Holloway D, Jiang S, Lu Y, Kieff E. Epstein-Barr virus nuclear antigen leader protein localizes to promoters and enhancers with cell transcription factors and EBNA2. Proc Natl Acad Sci U S A. 2013 Nov 12; 110(46):18537-42. PMID: 24167291.
    Citations: 31     Fields:    Translation:AnimalsCells
  41. Liu CD, Cheng CP, Fang JS, Chen LC, Zhao B, Kieff E, Peng CW. Modulation of Epstein-Barr virus nuclear antigen 2-dependent transcription by protein arginine methyltransferase 5. Biochem Biophys Res Commun. 2013 Jan 18; 430(3):1097-102. PMID: 23261437.
    Citations: 8     Fields:    Translation:HumansCells
  42. Liu CD, Chen YL, Min YL, Zhao B, Cheng CP, Kang MS, Chiu SJ, Kieff E, Peng CW. The nuclear chaperone nucleophosmin escorts an Epstein-Barr Virus nuclear antigen to establish transcriptional cascades for latent infection in human B cells. PLoS Pathog. 2012; 8(12):e1003084. PMID: 23271972; PMCID: PMC3521654.
    Citations: 16     Fields:    Translation:HumansCells
  43. Gulbahce N, Yan H, Dricot A, Padi M, Byrdsong D, Franchi R, Lee DS, Rozenblatt-Rosen O, Mar JC, Calderwood MA, Baldwin A, Zhao B, Santhanam B, Braun P, Simonis N, Huh KW, Hellner K, Grace M, Chen A, Rubio R, Marto JA, Christakis NA, Kieff E, Roth FP, Roecklein-Canfield J, Decaprio JA, Cusick ME, Quackenbush J, Hill DE, Münger K, Vidal M, Barabási AL. Viral perturbations of host networks reflect disease etiology. PLoS Comput Biol. 2012; 8(6):e1002531. PMID: 22761553.
    Citations: 69     Fields:    Translation:HumansCells
  44. Gewurz BE, Towfic F, Mar JC, Shinners NP, Takasaki K, Zhao B, Cahir-McFarland ED, Quackenbush J, Xavier RJ, Kieff E. Genome-wide siRNA screen for mediators of NF-?B activation. Proc Natl Acad Sci U S A. 2012 Feb 14; 109(7):2467-72. PMID: 22308454.
    Citations: 58     Fields:    Translation:HumansCells
  45. Zhao B, Zou J, Wang H, Johannsen E, Peng CW, Quackenbush J, Mar JC, Morton CC, Freedman ML, Blacklow SC, Aster JC, Bernstein BE, Kieff E. Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell growth. Proc Natl Acad Sci U S A. 2011 Sep 06; 108(36):14902-7. PMID: 21746931.
    Citations: 114     Fields:    Translation:HumansCells
  46. Wang H, Zou J, Zhao B, Johannsen E, Ashworth T, Wong H, Pear WS, Schug J, Blacklow SC, Arnett KL, Bernstein BE, Kieff E, Aster JC. Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells. Proc Natl Acad Sci U S A. 2011 Sep 06; 108(36):14908-13. PMID: 21737748.
    Citations: 142     Fields:    Translation:HumansAnimalsCells
  47. Gewurz BE, Mar JC, Padi M, Zhao B, Shinners NP, Takasaki K, Bedoya E, Zou JY, Cahir-McFarland E, Quackenbush J, Kieff E. Canonical NF-kappaB activation is essential for Epstein-Barr virus latent membrane protein 1 TES2/CTAR2 gene regulation. J Virol. 2011 Jul; 85(13):6764-73. PMID: 21543491.
    Citations: 25     Fields:    Translation:HumansCells
  48. Portal D, Zhao B, Calderwood MA, Sommermann T, Johannsen E, Kieff E. EBV nuclear antigen EBNALP dismisses transcription repressors NCoR and RBPJ from enhancers and EBNA2 increases NCoR-deficient RBPJ DNA binding. Proc Natl Acad Sci U S A. 2011 May 10; 108(19):7808-13. PMID: 21518914.
    Citations: 19     Fields:    Translation:HumansCells
  49. Maruo S, Zhao B, Johannsen E, Kieff E, Zou J, Takada K. Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression. Proc Natl Acad Sci U S A. 2011 Feb 01; 108(5):1919-24. PMID: 21245331.
    Citations: 75     Fields:    Translation:HumansCells
  50. Zhao B, Mar JC, Maruo S, Lee S, Gewurz BE, Johannsen E, Holton K, Rubio R, Takada K, Quackenbush J, Kieff E. Epstein-Barr virus nuclear antigen 3C regulated genes in lymphoblastoid cell lines. Proc Natl Acad Sci U S A. 2011 Jan 04; 108(1):337-42. PMID: 21173222.
    Citations: 30     Fields:    Translation:HumansCells
  51. Lee S, Sakakibara S, Maruo S, Zhao B, Calderwood MA, Holthaus AM, Lai CY, Takada K, Kieff E, Johannsen E. Epstein-Barr virus nuclear protein 3C domains necessary for lymphoblastoid cell growth: interaction with RBP-Jkappa regulates TCL1. J Virol. 2009 Dec; 83(23):12368-77. PMID: 19776126.
    Citations: 23     Fields:    Translation:HumansCells
  52. Peng CW, Zhao B, Chen HC, Chou ML, Lai CY, Lin SZ, Hsu HY, Kieff E. Hsp72 up-regulates Epstein-Barr virus EBNALP coactivation with EBNA2. Blood. 2007 Jun 15; 109(12):5447-54. PMID: 17341665; PMCID: PMC1890828.
    Citations: 13     Fields:    Translation:HumansCells
  53. Chen A, Zhao B, Kieff E, Aster JC, Wang F. EBNA-3B- and EBNA-3C-regulated cellular genes in Epstein-Barr virus-immortalized lymphoblastoid cell lines. J Virol. 2006 Oct; 80(20):10139-50. PMID: 17005691; PMCID: PMC1617319.
    Citations: 27     Fields:    Translation:HumansCells
  54. Jiménez-Ramírez C, Brooks AJ, Forshell LP, Yakimchuk K, Zhao B, Fulgham TZ, Sample CE. Epstein-Barr virus EBNA-3C is targeted to and regulates expression from the bidirectional LMP-1/2B promoter. J Virol. 2006 Nov; 80(22):11200-8. PMID: 16956945; PMCID: PMC1642179.
    Citations: 13     Fields:    Translation:HumansCells
  55. Yuan J, Cahir-McFarland E, Zhao B, Kieff E. Virus and cell RNAs expressed during Epstein-Barr virus replication. J Virol. 2006 Mar; 80(5):2548-65. PMID: 16474161; PMCID: PMC1395376.
    Citations: 97     Fields:    Translation:HumansCells
  56. Zhao B, Maruo S, Cooper A, R Chase M, Johannsen E, Kieff E, Cahir-McFarland E. RNAs induced by Epstein-Barr virus nuclear antigen 2 in lymphoblastoid cell lines. Proc Natl Acad Sci U S A. 2006 Feb 07; 103(6):1900-5. PMID: 16446431; PMCID: PMC1413661.
    Citations: 39     Fields:    Translation:HumansCells
  57. Ling PD, Peng RS, Nakajima A, Yu JH, Tan J, Moses SM, Yang WH, Zhao B, Kieff E, Bloch KD, Bloch DB. Mediation of Epstein-Barr virus EBNA-LP transcriptional coactivation by Sp100. EMBO J. 2005 Oct 19; 24(20):3565-75. PMID: 16177824; PMCID: PMC1276704.
    Citations: 44     Fields:    Translation:HumansCells
  58. Maruo S, Johannsen E, Illanes D, Cooper A, Zhao B, Kieff E. Epstein-Barr virus nuclear protein 3A domains essential for growth of lymphoblasts: transcriptional regulation through RBP-Jkappa/CBF1 is critical. J Virol. 2005 Aug; 79(16):10171-9. PMID: 16051810; PMCID: PMC1182629.
    Citations: 26     Fields:    Translation:HumansCells
  59. Peng CW, Zhao B, Kieff E. Four EBNA2 domains are important for EBNALP coactivation. J Virol. 2004 Oct; 78(20):11439-42. PMID: 15452270; PMCID: PMC521825.
    Citations: 14     Fields:    Translation:HumansCells
  60. Peng CW, Xue Y, Zhao B, Johannsen E, Kieff E, Harada S. Direct interactions between Epstein-Barr virus leader protein LP and the EBNA2 acidic domain underlie coordinate transcriptional regulation. Proc Natl Acad Sci U S A. 2004 Jan 27; 101(4):1033-8. PMID: 14732686; PMCID: PMC327146.
    Citations: 21     Fields:    Translation:HumansCells
  61. Zhao B, Dalbiès-Tran R, Jiang H, Ruf IK, Sample JT, Wang F, Sample CE. Transcriptional regulatory properties of Epstein-Barr virus nuclear antigen 3C are conserved in simian lymphocryptoviruses. J Virol. 2003 May; 77(10):5639-48. PMID: 12719556; PMCID: PMC154039.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  62. Zhao B, Sample CE. Epstein-barr virus nuclear antigen 3C activates the latent membrane protein 1 promoter in the presence of Epstein-Barr virus nuclear antigen 2 through sequences encompassing an spi-1/Spi-B binding site. J Virol. 2000 Jun; 74(11):5151-60. PMID: 10799590; PMCID: PMC110868.
    Citations: 68     Fields:    Translation:HumansCells
  63. Zhao B, Marshall DR, Sample CE. A conserved domain of the Epstein-Barr virus nuclear antigens 3A and 3C binds to a discrete domain of Jkappa. J Virol. 1996 Jul; 70(7):4228-36. PMID: 8676443; PMCID: PMC190353.
    Citations: 64     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.