Harvard Catalyst Profiles

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Toshihiro Shioda, M.D., Ph.D.

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R21CA290650 (SHIODA, TOSHIHIRO) Apr 7, 2025 - Mar 31, 2027
    NIH
    Reconstituting human testicular germ cell neoplasia in situ (GCNIS) in vitro using iPSC-derived primordial germ cell-like cells (PGCLCs) and genetically engineered human testicular cancer cells
    Role: Principal Investigator
  2. R21DA059789 (SHIODA, TOSHIHIRO) May 15, 2024 - Apr 30, 2026
    NIH
    Cannabinoids as an environmental risk factor of testicular cancer: Assessment using cell culture models of human and mouse primordial germ cells and by exposure of pregnant mice
    Role: Principal Investigator
  3. R01ES035401 (SHIODA, TOSHIHIRO) Apr 24, 2024 - Feb 28, 2029
    NIH
    Environmental chemicals impair epigenetic suppression of the endogenous retrovirus HML-2 in human primordial germ cells, predisposing the next generation to malignancies through HML-2 reactivation
    Role: Principal Investigator
  4. R21HD110839 (SHIODA, TOSHIHIRO) Aug 3, 2023 - Jul 31, 2025
    NIH
    Roles of the LTR5_Hs human-specific endogenous retroviruses in primordial germ cells
    Role: Principal Investigator
  5. R21ES034468 (SHIODA, TOSHIHIRO) Apr 1, 2023 - Mar 31, 2025
    NIH
    Applications of the long-term culture human primordial germ cell-like cells to toxicological assessments and mechanistic studies on chemically caused heritable human health threats
    Role: Principal Investigator

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© 2025 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.