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Anna W Sromek, Ph.D.

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21MH103718 (SROMEK, ANNA WACLAWA) Sep 19, 2014 - Aug 31, 2016
    F_18 Labeled D2 Agonist Ligands for PET Imaging of Dopaminergic Dysfunction
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Inkster JAH, Akurathi V, Sromek AW, Chen Y, Neumeyer JL, Packard AB. A non-anhydrous, minimally basic protocol for the simplification of nucleophilic 18F-fluorination chemistry. Sci Rep. 2020 04 22; 10(1):6818. PMID: 32321927.
  2. Xu Y, Sromek AW, Neumeyer JL. Identification of fluorinated (R)-(-)-aporphine derivatives as potent and selective ligands at serotonin 5-HT2C receptor. Bioorg Med Chem Lett. 2019 01 15; 29(2):230-233. PMID: 30545651.
    Citations:    Fields:    
  3. Subburaju S, Sromek AW, Seeman P, Neumeyer JL. New Dopamine D2 Receptor Agonist, [3H]MCL-536, for Detecting Dopamine D2high Receptors in Vivo. ACS Chem Neurosci. 2018 06 20; 9(6):1283-1289. PMID: 29641175.
    Citations:    Fields:    
  4. Lincoln L, Fisher R, Jackson MJ, Jenner P, Neumeyer J, Sromek AW, Lees AJ, Rose S. Oral r-(-)-11-o-valeryl-n-n-propylnoraporphine reverses motor deficits in mptp-treated marmosets. Mov Disord. 2016 09; 31(9):1381-8. PMID: 27133947.
    Citations: 1     Fields:    Translation:Animals
  5. Sromek AW, Zhang S, Akurathi V, Packard AB, Li W, Alagille D, Morley TJ, Baldwin R, Tamagnan G, Neumeyer JL. Convenient synthesis of 18F-radiolabeled R-(-)-N-n-propyl-2-(3-fluoropropanoxy-11-hydroxynoraporphine. J Labelled Comp Radiopharm. 2014 Dec; 57(14):725-9. PMID: 25400260.
    Citations: 1     Fields:    
  6. Finnema SJ, Stepanov V, Nakao R, Sromek AW, Zhang T, Neumeyer JL, George SR, Seeman P, Stabin MG, Jonsson C, Farde L, Halldin C. (18)F-MCL-524, an (18)F-Labeled Dopamine D2 and D3 Receptor Agonist Sensitive to Dopamine: A Preliminary PET Study. J Nucl Med. 2014 Jul; 55(7):1164-70. PMID: 24790219.
    Citations: 5     Fields:    Translation:Animals
  7. Sromek AW, Provencher BA, Russell S, Chartoff E, Knapp BI, Bidlack JM, Neumeyer JL. Preliminary pharmacological evaluation of enantiomeric morphinans. ACS Chem Neurosci. 2014 Feb 19; 5(2):93-9. PMID: 24393077.
    Citations: 2     Fields:    Translation:HumansAnimals
  8. Provencher BA, Sromek AW, Li W, Russell S, Chartoff E, Knapp BI, Bidlack JM, Neumeyer JL. Synthesis and pharmacological evaluation of aminothiazolomorphinans at the mu and kappa opioid receptors. J Med Chem. 2013 Nov 14; 56(21):8872-8. PMID: 24107104.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  9. Neumeyer JL, Zhang B, Zhang T, Sromek AW, Knapp BI, Cohen DJ, Bidlack JM. Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors. J Med Chem. 2012 Apr 26; 55(8):3878-90. PMID: 22439881.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  10. Zhang B, Zhang T, Sromek AW, Scrimale T, Bidlack JM, Neumeyer JL. Synthesis and binding affinity of novel mono- and bivalent morphinan ligands for ?, µ, and d opioid receptors. Bioorg Med Chem. 2011 May 01; 19(9):2808-16. PMID: 21482470.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  11. Sromek AW, Si YG, Zhang T, George SR, Seeman P, Neumeyer JL. Synthesis and Evaluation of Fluorinated Aporphines: Potential Positron Emission Tomography Ligands for D2 Receptors ACS Med Chem Lett. 2011 Mar 10; 2(3):189-194. PMID: 21666830.
    Citations: 2     
  12. Zhang T, Yan Z, Sromek A, Knapp BI, Scrimale T, Bidlack JM, Neumeyer JL. Aminothiazolomorphinans with mixed ? and µ opioid activity. J Med Chem. 2011 Mar 24; 54(6):1903-13. PMID: 21351746.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  13. Dudnik AS, Sromek AW, Rubina M, Kim JT, Kel'in AV, Gevorgyan V. Metal-catalyzed 1,2-shift of diverse migrating groups in allenyl systems as a new paradigm toward densely functionalized heterocycles. J Am Chem Soc. 2008 Jan 30; 130(4):1440-52. PMID: 18173272.
    Citations: 19     Fields:    Translation:Cells
  14. Schwier T, Sromek AW, Yap DM, Chernyak D, Gevorgyan V. Mechanistically diverse copper-, silver-, and gold-catalyzed acyloxy and phosphatyloxy migrations: efficient synthesis of heterocycles via cascade migration/cycloisomerization approach. J Am Chem Soc. 2007 Aug 15; 129(32):9868-78. PMID: 17658805.
    Citations: 17     Fields:    Translation:Cells
  15. Sromek AW, Gevorgyan V. Top. Curr. Chem. 1,2-Sulfur migrations. 2007; 274:77-124.
  16. Sromek AW, Rheingold AL, Wink DJ, Gevorgyan V. Synlett. Chemodivergent transformations of alkynyl imines. 2006; (14):2325-2328.
  17. Sromek AW, Rubina M, Gevorgyan V. 1,2-Halogen migration in haloallenyl ketones: regiodivergent synthesis of halofurans. J Am Chem Soc. 2005 Aug 03; 127(30):10500-1. PMID: 16045332.
    Citations: 18     Fields:    Translation:Cells
  18. Sromek AW, Kel'in AV, Gevorgyan V. A novel 1,2-migration of acyloxy, phosphatyloxy, and sulfonyloxy groups in allenes: efficient synthesis of tri- and tetrasubstituted furans. Angew Chem Int Ed Engl. 2004 Apr 19; 43(17):2280-2. PMID: 15108144.
    Citations: 18     Fields:    
  19. Park CH, Ryabova V, Seregin IV, Sromek AW, Gevorgyan V. Palladium-catalyzed arylation and heteroarylation of indolizines. Org Lett. 2004 Apr 01; 6(7):1159-62. PMID: 15040747.
    Citations: 29     Fields:    
  20. Rubin M, Sromek AW, Gevorgyan V. Synlett. New advances in selected metal-catalyzed annulations. 2003; (15):2265-2291.
  21. Kel'in AV, Sromek AW, Gevorgyan V. A novel Cu-assisted cycloisomerization of alkynyl imines: efficient synthesis of pyrroles and pyrrole-containing heterocycles. J Am Chem Soc. 2001 Mar 07; 123(9):2074-5. PMID: 11456838.
    Citations: 34     Fields:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.