Harvard Catalyst Profiles

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Dennis Paul Orgill, M.D., PH.D.

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Mentoring
current student opportunities
Wound Healing Study[login at prompt]
Available: 10/11/18, Expires: 10/01/20

You will join one of the main areas of investigation in our lab (Advanced scaffolds tissue engineering, Diabetic wound healing, Modulation of soft tissue regeneration, Healing through mechanical forces) and will be supported in the drafting/proposal of a comprehensive research plan related to innovative strategies for therapeutic wound healing and induction of tissue regeneration in vivo (mice) and in vitro. Students will be given the opportunity to familiarize themselves with state of the art research, translational and clinical literature on the topic as well as develop their skills in critical review of literature, application of correct scientific methods, development of a research plan, drafting of experimental protocols (including animals) for funding applications, reporting and publishing research. They will be taught hands-on animal surgery techniques in mice as well as histological processing and staining methods. Our research program fosters a collaborative environment in which students have the opportunity to work with a large number of investigators and labs (muscle regeneration, vascular surgery, general surgery, dermatology, orthopedics, diabetes, transplantation surgery, cell biology) in the surrounding region. Lab meetings are held weekly where students can share the progress of their research and hear updates on projects by fellow researchers. Main ongoing investigations include among others: – Generation of a model of chronic wounds in diabetic mice – Investigation of the effect of a matrix of surfactant micelles on wound healing in diabetic mice – Development of a novel scaffold by incorporating autologous tissue in Integra and PriMatrix – Optimization of an innovative method for soft tissue reconstruction through external volume expansion

completed student projects

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wei S, Orgill DP, Giatsidis G. Delivery of External Volume Expansion through Microdeformational Interfaces Safely Induces Angiogenesis in a Murine Model of Intact Diabetic Skin with Endothelial Cell Dysfunction. Plast Reconstr Surg. 2019 Feb; 143(2):453-464. PMID: 30531623.
    Citations:    Fields:    
  2. Icli B, Wu W, Ozdemir D, Li H, Haemmig S, Liu X, Giatsidis G, Cheng HS, Avci SN, Kurt M, Lee N, Guimaraes RB, Manica A, Marchini JF, Rynning SE, Risnes I, Hollan I, Croce K, Orgill DP, Feinberg MW. MicroRNA-135a-3p regulates angiogenesis and tissue repair by targeting p38 signaling in endothelial cells. FASEB J. 2019 Jan 22; fj201802063RR. PMID: 30668922.
    Citations:    Fields:    
  3. Contessi Negrini N, Bonnetier M, Giatsidis G, Orgill DP, Farè S, Marelli B. Tissue-mimicking gelatin scaffolds by alginate sacrificial templates for adipose tissue engineering. Acta Biomater. 2019 Jan 14. PMID: 30654214.
    Citations:    Fields:    
  4. Liu Y, Panayi AC, Bayer LR, Orgill DP. Current Available Cellular and Tissue-Based Products for Treatment of Skin Defects. Adv Skin Wound Care. 2019 Jan; 32(1):19-25. PMID: 30570555.
    Citations:    Fields:    
  5. Gabriel A, Gupta S, Orgill DP. Challenges and Management of Surgical Site Occurrences. Plast Reconstr Surg. 2019 Jan; 143(1S Management of Surgical Incisions Utilizing Closed-Incision Negative-Pressure Therapy):7S-10S. PMID: 30586096.
    Citations:    Fields:    
  6. Arnold PB, Orgill DP. Discussion: Is Reconstruction Preserving the First Ray or First Two Rays Better Than Full Transmetatarsal Amputation in Diabetic Foot? Plast Reconstr Surg. 2019 Jan; 143(1):306-307. PMID: 30589806.
    Citations:    Fields:    
  7. Gabriel A, Maxwell GP, Orgill DP. Introduction to "Management of Surgical Incisions Utilizing Closed-Incision Negative-Pressure Therapy". Plast Reconstr Surg. 2019 Jan; 143(1S Management of Surgical Incisions Utilizing Closed-Incision Negative-Pressure Therapy):4S-5S. PMID: 30586095.
    Citations:    Fields:    
  8. Panayi AC, Orgill DP. Current Use of Biological Scaffolds in Plastic Surgery. Plast Reconstr Surg. 2019 Jan; 143(1):209-220. PMID: 30286046.
    Citations:    Fields:    
  9. Wei S, Liu W, Gundogan B, Moscoso AV, Orgill DP, Giatsidis G. Delayed Postconditioning with External Volume Expansion Improves Survival of Adipose Tissue Grafts in a Murine Model. Plast Reconstr Surg. 2019 Jan; 143(1):99e-110e. PMID: 30325898.
    Citations:    Fields:    
  10. Rhodius P, Haddad A, Matsumine H, Sakthivel D, Ackermann M, Sinha I, Orgill DP, Giatsidis G. Noninvasive Flap Preconditioning by Foam-Mediated External Suction Improves the Survival of Fasciocutaneous Axial-Pattern Flaps in a Type 2 Diabetic Murine Model. Plast Reconstr Surg. 2018 Dec; 142(6):872e-883e. PMID: 30188471.
    Citations:    Fields:    
  11. Panayi AC, Orkaby AR, Sakthivel D, Endo Y, Varon D, Roh D, Orgill DP, Neppl RL, Javedan H, Bhasin S, Sinha I. Impact of frailty on outcomes in surgical patients: A systematic review and meta-analysis. Am J Surg. 2018 Nov 27. PMID: 30509455.
    Citations:    Fields:    
  12. Agha RA, Borrelli MR, Farwana R, Koshy K, Fowler AJ, Orgill DP. The PROCESS 2018 statement: Updating Consensus Preferred Reporting Of CasE Series in Surgery (PROCESS) guidelines. Int J Surg. 2018 Dec; 60:279-282. PMID: 30359781.
    Citations:    Fields:    
  13. Agha RA, Borrelli MR, Farwana R, Koshy K, Fowler AJ, Orgill DP. The SCARE 2018 statement: Updating consensus Surgical CAse REport (SCARE) guidelines. Int J Surg. 2018 Dec; 60:132-136. PMID: 30342279.
    Citations:    Fields:    
  14. Giatsidis G, Succar J, Haddad A, Lago G, Schaffer C, Wang X, Schilling B, Chnari E, Matsumine H, Orgill DP. Preclinical Optimization of a Shelf-Ready, Injectable, Human-Derived, Decellularized Allograft Adipose Matrix. Tissue Eng Part A. 2018 Oct 16. PMID: 30084731.
    Citations:    Fields:    
  15. Mella JR, Ross KM, Li GZ, Pomahac B, Raut CP, Orgill DP. Cutaneous Breast Radiation-associated Angiosarcoma: Anterior Chest Wall Reconstruction Options Following Extra-radical Resection. Plast Reconstr Surg Glob Open. 2018 Sep; 6(9):e1938. PMID: 30349797.
    Citations:    
  16. DiDomenico LA, Orgill DP, Galiano RD, Serena TE, Carter MJ, Kaufman JP, Young NJ, Jacobs AM, Zelen CM. Use of an aseptically processed, dehydrated human amnion and chorion membrane improves likelihood and rate of healing in chronic diabetic foot ulcers: A prospective, randomised, multi-centre clinical trial in 80 patients. Int Wound J. 2018 Dec; 15(6):950-957. PMID: 30019528.
    Citations:    Fields:    
  17. Giatsidis G, Guyette JP, Ott HC, Orgill DP. Development of a large-volume human-derived adipose acellular allogenic flap by perfusion decellularization. Wound Repair Regen. 2018 03; 26(2):245-250. PMID: 29617055.
    Citations:    Fields:    
  18. Agha RA, Pidgeon TE, Borrelli MR, Dowlut N, Orkar TK, Ahmed M, Pujji O, Orgill DP. Validated Outcomes in the Grafting of Autologous Fat to the Breast: The VOGUE Study. Development of a Core Outcome Set for Research and Audit. Plast Reconstr Surg. 2018 05; 141(5):633e-638e. PMID: 29697603.
    Citations:    Fields:    Translation:Humans
  19. Zelen CM, Orgill DP, Serena TE, Galiano RE, Carter MJ, DiDomenico LA, Keller J, Kaufman JP, Li WW. An aseptically processed, acellular, reticular, allogenic human dermis improves healing in diabetic foot ulcers: A prospective, randomised, controlled, multicentre follow-up trial. Int Wound J. 2018 Oct; 15(5):731-739. PMID: 29682897.
    Citations:    Fields:    Translation:Humans
  20. Wang C, Luan J, Panayi AC, Orgill DP, Xin M. Complications in breast augmentation with textured versus smooth breast implants: a systematic review protocol. BMJ Open. 2018 04 10; 8(4):e020671. PMID: 29643164.
    Citations:    Fields:    
  21. Heit YI, Orgill DP. Discussion: External Volume Expansion Up-Regulates CXCL12 Expression and Enhances Mesenchymal Stromal Cell Recruitment toward Expanded Prefabricated Adipose Tissue in Rats. Plast Reconstr Surg. 2018 04; 141(4):538e-539e. PMID: 29595729.
    Citations:    Fields:    Translation:AnimalsCells
  22. Ross KM, Moscoso AV, Bayer LR, Rosselli-Risal L, Orgill DP. Plastic Surgery Complications from Medical Tourism Treated in a U.S. Academic Medical Center. Plast Reconstr Surg. 2018 04; 141(4):517e-523e. PMID: 29595725.
    Citations:    Fields:    Translation:Humans
  23. Panayi AC, Agha RA, Sieber BA, Orgill DP. Impact of Obesity on Outcomes in Breast Reconstruction: A Systematic Review and Meta-Analysis. J Reconstr Microsurg. 2018 Jun; 34(5):363-375. PMID: 29510420.
    Citations:    Fields:    Translation:Humans
  24. Thorlacius L, Garg A, Ingram JR, Villumsen B, Theut Riis P, Gottlieb AB, Merola JF, Dellavalle R, Ardon C, Baba R, Bechara FG, Cohen AD, Daham N, Davis M, Emtestam L, Fernández-Peñas P, Filippelli M, Gibbons A, Grant T, Guilbault S, Gulliver S, Harris C, Harvent C, Houston K, Kirby JS, Matusiak L, Mehdizadeh A, Mojica T, Okun M, Orgill D, Pallack L, Parks-Miller A, Prens EP, Randell S, Rogers C, Rosen CF, Choon SE, van der Zee HH, Christensen R, Jemec GBE. Towards global consensus on core outcomes for hidradenitis suppurativa research: an update from the HISTORIC consensus meetings I and II. Br J Dermatol. 2018 Mar; 178(3):715-721. PMID: 29080368.
    Citations: 1     Fields:    
  25. Roh DS, Orgill DP. Discussion: Early Macrophage Infiltration Improves Fat Graft Survival by Inducing Angiogenesis and Hematopoietic Stem Cell Recruitment. Plast Reconstr Surg. 2018 02; 141(2):387-388. PMID: 29369989.
    Citations:    Fields:    Translation:HumansCells
  26. Ogawa R, Daya M, Orgill DP. Discussion: Percutaneous Mesh Expansion: A Regenerative Wound Closure Alternative. Plast Reconstr Surg. 2018 02; 141(2):458-459. PMID: 29369998.
    Citations:    Fields:    Translation:Humans
  27. Sinha I, Giatsidis G, Orgill DP. Discussion: Protective Effect of Hydrogen Gas Inhalation on Muscular Damage Using a Mouse Hindlimb Ischemia-Reperfusion Injury Model. Plast Reconstr Surg. 2017 Dec; 140(6):1207-1208. PMID: 29176415.
    Citations:    Fields:    
  28. Giatsidis G, Cheng L, Haddad A, Ji K, Succar J, Lancerotto L, Lujan-Hernandez J, Fiorina P, Matsumine H, Orgill DP. Noninvasive induction of angiogenesis in tissues by external suction: sequential optimization for use in reconstructive surgery. Angiogenesis. 2018 Feb; 21(1):61-78. PMID: 29147813.
    Citations:    Fields:    
  29. Sîrbulescu RF, Boehm CK, Soon E, Wilks MQ, Ilies I, Yuan H, Maxner B, Chronos N, Kaittanis C, Normandin MD, El Fakhri G, Orgill DP, Sluder AE, Poznansky MC. Mature B cells accelerate wound healing after acute and chronic diabetic skin lesions. Wound Repair Regen. 2017 09; 25(5):774-791. PMID: 28922523.
    Citations: 2     Fields:    Translation:AnimalsCells
  30. Agha RA, Borrelli MR, Vella-Baldacchino M, Thavayogan R, Orgill DP. The STROCSS statement: Strengthening the Reporting of Cohort Studies in Surgery. Int J Surg. 2017 Oct; 46:198-202. PMID: 28890409.
    Citations: 37     Fields:    Translation:Humans
  31. Agha RA, Fowler AJ, Saeta A, Barai I, Rajmohan S, Orgill DP. Erratum to "Erratum to "The SCARE guidelines: Consensus-based surgical case report guidelines" [Int. J. Surg. 34 (2016) 180-186]" [Int. J. Surg. 36 (2016) 396]. Int J Surg. 2017 11; 47:151. PMID: 28847721.
    Citations: 1     Fields:    
  32. Agha RA, Borrelli MR, Farwana R, Kusu-Orkar T, Millip MC, Thavayogan R, Garner J, Darhouse N, Orgill DP. Impact of the PROCESS guideline on the reporting of surgical case series: A before and after study. Int J Surg. 2017 Sep; 45:92-97. PMID: 28760706.
    Citations: 2     Fields:    Translation:Humans
  33. Agha RA, Farwana R, Borrelli MR, Tickunas T, Kusu-Orkar T, Millip MC, Thavayogan R, Garner J, Orgill DP. Impact of the SCARE guideline on the reporting of surgical case reports: A before and after study. Int J Surg. 2017 Sep; 45:144-148. PMID: 28757396.
    Citations: 3     Fields:    Translation:Humans
  34. DiDomenico LA, Orgill DP, Galiano RD, Serena TE, Carter MJ, Kaufman JP, Young NJ, Zelen CM. A Retrospective Crossover Study of the Use of Aseptically Processed Placental Membrane in the Treatment of Chronic Diabetic Foot Ulcers. Wounds. 2017 Jul 26. PMID: 28873060.
    Citations:    Fields:    
  35. Seth AK, Friedstat JS, Orgill DP, Pribaz JJ, Halvorson EG. Microsurgical Burn Reconstruction. Clin Plast Surg. 2017 Oct; 44(4):823-832. PMID: 28888307.
    Citations:    Fields:    Translation:Humans
  36. Szabo Eltorai A, Huang CC, Lu JT, Ogura A, Caterson SA, Orgill DP. Selective Intraoperative Vasopressor Use Is Not Associated with Increased Risk of DIEP Flap Complications. Plast Reconstr Surg. 2017 Jul; 140(1):70e-77e. PMID: 28654605.
    Citations:    Fields:    Translation:Humans
  37. Agha RA, Barai I, Rajmohan S, Lee S, Anwar MO, Fowler AJ, Orgill DP, Altman DG. Support for reporting guidelines in surgical journals needs improvement: A systematic review. Int J Surg. 2017 Sep; 45:14-17. PMID: 28673865.
    Citations: 4     Fields:    Translation:Humans
  38. Pidgeon TE, Limb C, Agha RA, Whitehurst K, Chandrakumar C, Wellstead G, Fowler AJ, Orgill DP. The use of study registration and protocols in plastic surgery research: A systematic review. Int J Surg. 2017 Aug; 44:215-222. PMID: 28625821.
    Citations:    Fields:    Translation:Humans
  39. Chin MS, Chappell AG, Giatsidis G, Perry DJ, Lujan-Hernandez J, Haddad A, Matsumine H, Orgill DP, Lalikos JF. Hyperspectral Imaging Provides Early Prediction of Random Axial Flap Necrosis in a Preclinical Model. Plast Reconstr Surg. 2017 Jun; 139(6):1285e-1290e. PMID: 28538567.
    Citations:    Fields:    Translation:Animals
  40. Giatsidis G, Cheng L, Facchin F, Haddad A, Lujan-Hernandez J, Lancerotto L, Nabzdyk CG, Matsumine H, Orgill DP. Moderate-Intensity Intermittent External Volume Expansion Optimizes the Soft-Tissue Response in a Murine Model. Plast Reconstr Surg. 2017 Apr; 139(4):882-890. PMID: 28350665.
    Citations: 2     Fields:    Translation:Animals
  41. Haddad AG, Giatsidis G, Orgill DP, Halvorson EG. Skin Substitutes and Bioscaffolds: Temporary and Permanent Coverage. Clin Plast Surg. 2017 Jul; 44(3):627-634. PMID: 28576252.
    Citations:    Fields:    Translation:Humans
  42. Li GZ, Fairweather M, Wang J, Orgill DP, Bertagnolli MM, Raut CP. Cutaneous Radiation-associated Breast Angiosarcoma: Radicality of Surgery Impacts Survival. Ann Surg. 2017 04; 265(4):814-820. PMID: 28267696.
    Citations: 2     Fields:    Translation:Humans
  43. Matsumine H, Numakura K, Tsunoda S, Wang H, Matsumine R, Climov M, Giatsidis G, Sukhatme VP, Orgill DP. Adipose-derived aldehyde dehydrogenase-expressing cells promote dermal regenerative potential with collagen-glycosaminoglycan scaffold. Wound Repair Regen. 2017 01; 25(1):109-119. PMID: 28230922.
    Citations: 1     Fields:    Translation:AnimalsCells
  44. Zelen CM, Orgill DP, Serena TE, Galiano RD, Carter MJ, DiDomenico LA, Kaufman JP, Keller J, Young NJ, Li WW. Human Reticular Acellular Dermal Matrix in the Healing of Chronic Diabetic Foot Ulcerations that Failed Standard Conservative Treatment: A Retrospective Crossover Study. Wounds. 2017 Feb; 29(2):39-45. PMID: 28272011.
    Citations: 1     Fields:    Translation:Humans
  45. Cheng L, Ji K, Shih TY, Haddad A, Giatsidis G, Mooney DJ, Orgill DP, Nabzdyk CS. Injectable Shape-Memorizing Three-Dimensional Hyaluronic Acid Cryogels for Skin Sculpting and Soft Tissue Reconstruction. Tissue Eng Part A. 2017 03; 23(5-6):243-251. PMID: 27875939.
    Citations: 1     Fields:    Translation:Animals
  46. Ricci JA, Bayer LR, Orgill DP. Evidence-Based Medicine: The Evaluation and Treatment of Pressure Injuries. Plast Reconstr Surg. 2017 Jan; 139(1):275e-286e. PMID: 28027261.
    Citations: 2     Fields:    Translation:Humans
  47. Agha RA, Fowler AJ, Saeta A, Barai I, Rajmohan S, Orgill DP. Erratum to "The SCARE guidelines: Consensus-based surgical case report guidelines" [Int. J. Surg. 34 (2016) 180-186]. Int J Surg. 2016 12; 36(Pt A):396. PMID: 27851898.
    Citations: 8     Fields:    
  48. Agha RA, Fowler AJ, Pidgeon TE, Wellstead G, Orgill DP. The Need for Core Outcome Reporting in Autologous Fat Grafting for Breast Reconstruction. Ann Plast Surg. 2016 Nov; 77(5):506-512. PMID: 26545226.
    Citations: 3     Fields:    Translation:Humans
  49. Agha RA, Fowler AJ, Rajmohan S, Barai I, Orgill DP. Preferred reporting of case series in surgery; the PROCESS guidelines. Int J Surg. 2016 Dec; 36(Pt A):319-323. PMID: 27770639.
    Citations: 126     Fields:    Translation:Humans
  50. DiDomenico LA, Orgill DP, Galiano RD, Serena TE, Carter MJ, Kaufman JP, Young NJ, Zelen CM. Aseptically Processed Placental Membrane Improves Healing of Diabetic Foot Ulcerations: Prospective, Randomized Clinical Trial. Plast Reconstr Surg Glob Open. 2016 Oct; 4(10):e1095. PMID: 27826487.
    Citations: 3     
  51. Dasgupta A, Orgill D, Galiano RD, Zelen CM, Huang YC, Chnari E, Li WW. A Novel Reticular Dermal Graft Leverages Architectural and Biological Properties to Support Wound Repair. Plast Reconstr Surg Glob Open. 2016 Oct; 4(10):e1065. PMID: 27826469.
    Citations:    
  52. Lujan-Hernandez J, Lancerotto L, Nabzdyk C, Hassan KZ, Giatsidis G, Khouri RK, Chin MS, Bassetto F, Lalikos JF, Orgill DP. Reply: Induction of Adipogenesis by External Volume Expansion. Plast Reconstr Surg. 2016 10; 138(4):770e-2e. PMID: 27307329.
    Citations:    Fields:    Translation:HumansCells
  53. Najjar PA, Madenci AL, Zogg CK, Schneider EB, Dankers CA, Pimentel MT, Chabria AS, Goldberg JE, Sharma G, Piazza G, Bleday R, Orgill DP, Kachalia A. Implementation of a Comprehensive Post-Discharge Venous Thromboembolism Prophylaxis Program for Abdominal and Pelvic Surgery Patients. J Am Coll Surg. 2016 12; 223(6):804-813. PMID: 27693288.
    Citations:    Fields:    Translation:Humans
  54. Agha R, Fowler AJ, Limb C, Al Omran Y, Sagoo H, Koshy K, Jafree DJ, Anwar MO, McCullogh P, Orgill DP. The First 500 Registrations to the Research Registry®: Advancing Registration of Under-Registered Study Types. Front Surg. 2016; 3:50. PMID: 27695693.
    Citations: 1     
  55. Agha RA, Fowler AJ, Saeta A, Barai I, Rajmohan S, Orgill DP. The SCARE Statement: Consensus-based surgical case report guidelines. Int J Surg. 2016 Oct; 34:180-186. PMID: 27613565.
    Citations: 1048     Fields:    Translation:Humans
  56. Climov M, Bayer LR, Moscoso AV, Matsumine H, Orgill DP. The Role of Dermal Matrices in Treating Inflammatory and Diabetic Wounds. Plast Reconstr Surg. 2016 Sep; 138(3 Suppl):148S-57S. PMID: 27556755.
    Citations: 1     Fields:    Translation:Humans
  57. Agha RA, Fowler AJ, Lee SY, Gundogan B, Whitehurst K, Sagoo HK, Jeong KJ, Altman DG, Orgill DP. Systematic review of the methodological and reporting quality of case series in surgery. Br J Surg. 2016 Sep; 103(10):1253-8. PMID: 27511619.
    Citations: 1     Fields:    Translation:Humans
  58. Caterson SA, Singh M, Orgill D, Ghazinouri R, Han E, Ciociolo G, Laskowski K, Greenberg JO. Erratum: Development of Standardized Clinical Assessment and Management Plans (SCAMPs) in the Field of Plastic & Reconstructive Surgery: A Quality Improvement Project: Erratum. Plast Reconstr Surg Glob Open. 2016 Jul; 4(7):e510. PMID: 27536468.
    Citations:    
  59. Lazar HL, Salm TV, Engelman R, Orgill D, Gordon S. Prevention and management of sternal wound infections. J Thorac Cardiovasc Surg. 2016 10; 152(4):962-72. PMID: 27555340.
    Citations: 5     Fields:    Translation:Humans
  60. Agha RA, Orgill DP. Commentary on: Autologous Fat Grafting in Cosmetic Breast Augmentation: A Systematic Review on Radiological Safety, Complications, Volume Retention, and Patient/Surgeon Satisfaction. Aesthet Surg J. 2016 10; 36(9):1008-9. PMID: 27461486.
    Citations:    Fields:    Translation:Humans
  61. Huang C, Du Y, Nabzdyk CS, Ogawa R, Koyama T, Orgill DP, Fu X. Regeneration of hair and other skin appendages: A microenvironment-centric view. Wound Repair Regen. 2016 Sep; 24(5):759-766. PMID: 27256925.
    Citations: 2     Fields:    
  62. Orgill DP, Hergrueter CA. Discussion: Strategies for Postoperative Seroma Prevention: A Systematic Review. Plast Reconstr Surg. 2016 07; 138(1):253-4. PMID: 27348658.
    Citations:    Fields:    Translation:Humans
  63. Matsumine H, Numakura K, Climov M, Watanabe Y, Giatsidis G, Orgill DP. Facial-nerve regeneration ability of a hybrid artificial nerve conduit containing uncultured adipose-derived stromal vascular fraction: An experimental study. Microsurgery. 2017 Oct; 37(7):808-818. PMID: 27273726.
    Citations:    Fields:    Translation:AnimalsCells
  64. Agha RA, Fowler AJ, Pidgeon TE, Wellstead G, Orgill DP. Protocol for the development of a core outcome set for autologous fat grafting to the breast. Int J Surg. 2016 Jul; 31:104-6. PMID: 27262878.
    Citations: 2     Fields:    Translation:Humans
  65. Katagiri S, Park K, Maeda Y, Rao TN, Khamaisi M, Li Q, Yokomizo H, Mima A, Lancerotto L, Wagers A, Orgill DP, King GL. Overexpressing IRS1 in Endothelial Cells Enhances Angioblast Differentiation and Wound Healing in Diabetes and Insulin Resistance. Diabetes. 2016 09; 65(9):2760-71. PMID: 27217486; PMCID: PMC5001189.
    Citations: 3     Fields:    Translation:AnimalsCells
  66. Agha RA, Wellstead G, Sagoo H, Al Omran Y, Barai I, Rajmohan S, Fowler AJ, Orgill DP, Rusby JE. Nipple sparing versus skin sparing mastectomy: a systematic review protocol. BMJ Open. 2016 05 20; 6(5):e010151. PMID: 27207622.
    Citations:    Fields:    Translation:Humans
  67. Agha RA, Lee SY, Jeong KJ, Fowler AJ, Orgill DP. Reporting Quality of Observational Studies in Plastic Surgery Needs Improvement: A Systematic Review. Ann Plast Surg. 2016 May; 76(5):585-9. PMID: 25643190.
    Citations: 7     Fields:    
  68. Zelen CM, Orgill DP, Serena T, Galiano R, Carter MJ, DiDomenico LA, Keller J, Kaufman J, Li WW. A prospective, randomised, controlled, multicentre clinical trial examining healing rates, safety and cost to closure of an acellular reticular allogenic human dermis versus standard of care in the treatment of chronic diabetic foot ulcers. Int Wound J. 2017 Apr; 14(2):307-315. PMID: 27073000.
    Citations: 4     Fields:    Translation:Humans
  69. Maruthappu M, Duclos A, Zhou CD, Lipsitz SR, Wright J, Orgill D, Carty MJ. The impact of team familiarity and surgical experience on operative efficiency: a retrospective analysis. J R Soc Med. 2016 Apr; 109(4):147-53. PMID: 27053357; PMCID: PMC4827107.
    Citations: 2     Fields:    Translation:Humans
  70. Lee SY, Sagoo H, Whitehurst K, Wellstead G, Fowler AJ, Agha RA, Orgill D. Compliance of Systematic Reviews in Plastic Surgery With the PRISMA Statement. JAMA Facial Plast Surg. 2016 Mar-Apr; 18(2):101-5. PMID: 26719993.
    Citations: 2     Fields:    
  71. Wakeam E, Hyder JA, Lipsitz SR, Cohen ME, Orgill DP, Zinner MJ, Ko CY, Hall BL, Finlayson SR. Hospital-level Variation in Secondary Complications After Surgery. Ann Surg. 2016 Mar; 263(3):493-501. PMID: 25876007.
    Citations: 2     Fields:    Translation:Humans
  72. Sinha I, Orgill DP. Discussion: Opposite Effects of Soluble Factors Secreted by Adipose Tissue on Proliferating and Quiescent Osteosarcoma Cells. Plast Reconstr Surg. 2016 Mar; 137(3):876-7. PMID: 26910667.
    Citations:    Fields:    Translation:HumansAnimals
  73. Agha RA, Orgill DP. Discussion: A Systematic Review of Surgical Randomized Controlled Trials: Part I. Risk of Bias and Outcomes: Common Pitfalls Plastic Surgeons Can Overcome. Plast Reconstr Surg. 2016 Feb; 137(2):707. PMID: 26818310.
    Citations:    Fields:    
  74. Agha RA, Fowler AJ, Saetta A, Barai I, Rajmohan S, Orgill DP. A protocol for the development of reporting criteria for surgical case reports: The SCARE statement. Int J Surg. 2016 Mar; 27:187-9. PMID: 26828281.
    Citations: 51     Fields:    Translation:Humans
  75. Khamaisi M, Katagiri S, Keenan H, Park K, Maeda Y, Li Q, Qi W, Thomou T, Eschuk D, Tellechea A, Veves A, Huang C, Orgill DP, Wagers A, King GL. PKCd inhibition normalizes the wound-healing capacity of diabetic human fibroblasts. J Clin Invest. 2016 Mar 01; 126(3):837-53. PMID: 26808499; PMCID: PMC4767341.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  76. Icli B, Nabzdyk CS, Lujan-Hernandez J, Cahill M, Auster ME, Wara AK, Sun X, Ozdemir D, Giatsidis G, Orgill DP, Feinberg MW. Regulation of impaired angiogenesis in diabetic dermal wound healing by microRNA-26a. J Mol Cell Cardiol. 2016 Feb; 91:151-9. PMID: 26776318; PMCID: PMC4764471.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  77. Agha RA, Orgill DP. Evidence-Based Plastic Surgery: Its Rise, Importance, and a Practical Guide. Aesthet Surg J. 2016 Mar; 36(3):366-71. PMID: 26746230.
    Citations:    Fields:    Translation:Humans
  78. Lujan-Hernandez J, Lancerotto L, Nabzdyk C, Hassan KZ, Giatsidis G, Khouri RK, Chin MS, Bassetto F, Lalikos JF, Orgill DP. Induction of Adipogenesis by External Volume Expansion. Plast Reconstr Surg. 2016 Jan; 137(1):122-31. PMID: 26710016.
    Citations: 5     Fields:    Translation:AnimalsCells
  79. Orgill DP, Smink DS. Discussion: Large Contaminated Ventral Hernia Repair Using Component Separation Technique with Synthetic Mesh. Plast Reconstr Surg. 2015 Dec; 136(6):806e-7e. PMID: 26595035.
    Citations:    Fields:    Translation:Humans
  80. Nyame TT, Chiang HA, Leavitt T, Ozambela M, Orgill DP. Tissue-Engineered Skin Substitutes. Plast Reconstr Surg. 2015 Dec; 136(6):1379-88. PMID: 26595026.
    Citations: 5     Fields:    Translation:Humans
  81. Chin MS, Freniere BB, Lancerotto L, Lujan-Hernandez J, Saleeby JH, Lo YC, Orgill DP, Lalikos JF, Fitzgerald TJ. Hyperspectral Imaging as an Early Biomarker for Radiation Exposure and Microcirculatory Damage. Front Oncol. 2015; 5:232. PMID: 26579490; PMCID: PMC4620692.
    Citations: 2     
  82. Agha R, Fowler AJ, Lee SY, Gundogan B, Whitehurst K, Sagoo H, Jeong KJ, Altman DG, Orgill DP. A systematic review protocol for reporting deficiencies within surgical case series. BMJ Open. 2015 Oct 05; 5(10):e008007. PMID: 26438134.
    Citations:    Fields:    Translation:Humans
  83. Janis JE, Khansa I, Lehrman CR, Orgill DP, Pomahac B. Reconstructive Management of Devastating Electrical Injuries to the Face. Plast Reconstr Surg. 2015 Oct; 136(4):839-47. PMID: 26090762.
    Citations: 2     Fields:    Translation:Humans
  84. Agha R, Fowler A, Orgill DP. Tissue-Engineered Breast Reconstruction with Brava-Assisted Fat Grafting: A 7-Year, 488-Patient, Multicenter Experience. Plast Reconstr Surg. 2015 Oct; 136(4):556e-7e. PMID: 26110212.
    Citations:    Fields:    Translation:Humans
  85. Caterson SA, Singh M, Orgill D, Ghazinouri R, Han E, Ciociolo G, Laskowski K, Greenberg JO. Development of Standardized Clinical Assessment and Management Plans (SCAMPs) in Plastic and Reconstructive Surgery. Plast Reconstr Surg Glob Open. 2015 Sep; 3(9):e510. PMID: 26495223; PMCID: PMC4596435.
    Citations: 2     
  86. Offodile AC, Pathak A, Wenger J, Orgill DP, Guo L. Prevalence and Patient-Level Risk Factors for 30-Day Readmissions Following Free Tissue Transfer for Head and Neck Cancer. JAMA Otolaryngol Head Neck Surg. 2015 Sep; 141(9):783-9. PMID: 26204558.
    Citations: 3     Fields:    Translation:Humans
  87. Min H, Morales DR, Orgill D, Smink DS, Yule S. Systematic review of coaching to enhance surgeons' operative performance. Surgery. 2015 Nov; 158(5):1168-91. PMID: 25956742.
    Citations: 4     Fields:    Translation:Humans
  88. Maruthappu M, Duclos A, Lipsitz SR, Orgill D, Carty MJ. Surgical learning curves and operative efficiency: a cross-specialty observational study. BMJ Open. 2015 Mar 13; 5(3):e006679. PMID: 25770229.
    Citations: 5     Fields:    Translation:Humans
  89. Offodile AC, Aherrera AS, Wenger J, Tsai T, Orgill DP, Guo L. Impact of Specialty Training on the Association between Flap Size and Incidence of Complications following Microvascular Head and Neck Reconstruction for Cancer. J Reconstr Microsurg. 2015 Jun; 31(5):348-54. PMID: 25769086.
    Citations:    Fields:    Translation:Humans
  90. Gobble RM, Orgill DP. Reply: Ketorolac does not increase postoperative bleeding: a meta-analysis of randomized controlled trials. Plast Reconstr Surg. 2015 Mar; 135(3):649e. PMID: 25635330.
    Citations:    Fields:    Translation:Humans
  91. Gibbons GW, Orgill DP, Serena TE, Novoung A, O'Connell JB, Li WW, Driver VR. A prospective, randomized, controlled trial comparing the effects of noncontact, low-frequency ultrasound to standard care in healing venous leg ulcers. Ostomy Wound Manage. 2015 Jan; 61(1):16-29. PMID: 25581604.
    Citations: 2     Fields:    Translation:Humans
  92. Halvorson EG, Orgill DP. Discussion: reverse lymphatic mapping: a new technique for maximizing safety in vascularized lymph node transfer. Plast Reconstr Surg. 2015 Jan; 135(1):286-8. PMID: 25539312.
    Citations:    Fields:    Translation:Humans
  93. Fairweather M, Heit YI, Buie J, Rosenberg LM, Briggs A, Orgill DP, Bertagnolli MM. Celecoxib inhibits early cutaneous wound healing. J Surg Res. 2015 Apr; 194(2):717-24. PMID: 25588948.
    Citations: 7     Fields:    Translation:AnimalsCells
  94. Agha RA, Fowler AJ, Herlin C, Goodacre TE, Orgill DP. Use of autologous fat grafting for breast reconstruction: a systematic review with meta-analysis of oncological outcomes. J Plast Reconstr Aesthet Surg. 2015 Feb; 68(2):143-61. PMID: 25591409.
    Citations: 16     Fields:    Translation:Humans
  95. Khouri RK, Khouri RE, Lujan-Hernandez JR, Khouri KR, Lancerotto L, Orgill DP. Diffusion and perfusion: the keys to fat grafting. Plast Reconstr Surg Glob Open. 2014 Sep; 2(9):e220. PMID: 25426403; PMCID: PMC4229279.
    Citations: 7     
  96. Lancerotto L, Orgill DP. Mechanoregulation of Angiogenesis in Wound Healing. Adv Wound Care (New Rochelle). 2014 Oct 01; 3(10):626-634. PMID: 25302137.
    Citations: 8     
  97. Ogawa R, Orgill DP, Murphy GF, Mizuno S. Hydrostatic pressure-driven three-dimensional cartilage induction using human adipose-derived stem cells and collagen gels. Tissue Eng Part A. 2015 Jan; 21(1-2):257-66. PMID: 25060524.
    Citations: 3     Fields:    Translation:HumansCells
  98. Maruthappu M, El-Harasis MA, Nagendran M, Orgill DP, McCulloch P, Duclos A, Carty MJ. Systematic review of methodological quality of individual performance measurement in surgery. Br J Surg. 2014 Nov; 101(12):1491-8; discussion 1498. PMID: 25228439.
    Citations: 2     Fields:    Translation:Humans
  99. Succar J, Douaiher J, Lancerotto L, Li Q, Yamaguchi R, Younan G, Pejler G, Orgill DP. The role of mouse mast cell proteases in the proliferative phase of wound healing in microdeformational wound therapy. Plast Reconstr Surg. 2014 Sep; 134(3):459-67. PMID: 24814421.
    Citations: 5     Fields:    Translation:AnimalsCells
  100. Wakeam E, Hyder JA, Tsai TC, Lipsitz SR, Orgill DP, Finlayson SR. Complication timing and association with mortality in the American College of Surgeons' National Surgical Quality Improvement Program database. J Surg Res. 2015 Jan; 193(1):77-87. PMID: 25260955.
    Citations: 3     Fields:    Translation:Humans
  101. Can A, Orgill DP, Dietmar Ulrich JO, Mureau MA. The myocutaneous trapezius flap revisited: a treatment algorithm for optimal surgical outcomes based on 43 flap reconstructions. J Plast Reconstr Aesthet Surg. 2014 Dec; 67(12):1669-79. PMID: 25175273.
    Citations: 2     Fields:    Translation:Humans
  102. Nyame TT, Chiang HA, Orgill DP. Clinical applications of skin substitutes. Surg Clin North Am. 2014 Aug; 94(4):839-50. PMID: 25085091.
    Citations: 6     Fields:    Translation:Humans
  103. Caterson SA, Orgill DP. Discussion: Natrelle round silicone breast implants: core study results at 10 years. Plast Reconstr Surg. 2014 Jun; 133(6):1362-3. PMID: 24867718.
    Citations:    Fields:    Translation:Humans
  104. Bailey AP, Lancerotto L, Gridley C, Orgill DP, Nguyen H, Pescarini E, Lago G, Gargiulo AR. Greater surgical precision of a flexible carbon dioxide laser fiber compared to monopolar electrosurgery in porcine myometrium. J Minim Invasive Gynecol. 2014 Nov-Dec; 21(6):1103-9. PMID: 24858988.
    Citations:    Fields:    Translation:Animals
  105. Huang C, Leavitt T, Bayer LR, Orgill DP. In brief. Curr Probl Surg. 2014 Jul; 51(7):298-9. PMID: 24935078.
    Citations:    
  106. Huang C, Leavitt T, Bayer LR, Orgill DP. Effect of negative pressure wound therapy on wound healing. Curr Probl Surg. 2014 Jul; 51(7):301-31. PMID: 24935079.
    Citations: 33     Fields:    Translation:Humans
  107. Orgill DP, Pribaz JJ. Discussion: aesthetic applications of brava-assisted megavolume fat grafting to the breasts: a 9-year, 476-patient, multicenter experience. Plast Reconstr Surg. 2014 Apr; 133(4):808-9. PMID: 24675186.
    Citations:    
  108. Agha RA, Gundogan B, Fowler AJ, Bragg TW, Orgill DP. The efficacy of the Cook-Swartz implantable Doppler in the detection of free-flap compromise: a systematic review protocol. BMJ Open. 2014 Mar 12; 4(3):e004253. PMID: 24622948; PMCID: PMC3963127.
    Citations:    Fields:    Translation:Humans
  109. Lujan-Hernandez JR, Lancerotto L, Nabzdyk C, Hassan KZ, Khouri RK, Zartab H, Chin MS, Bassetto F, Lalikos JF, Orgill DP. Abstract 125: adipogenesis by external volume expansion. Plast Reconstr Surg. 2014 Mar; 133(3 Suppl):142. PMID: 25942236.
    Citations: 1     Fields:    
  110. Lancerotto L, Chin MS, Freniere B, Lujan-Hernandez JR, Li Q, Valderrama Vasquez A, Bassetto F, Del Vecchio DA, Lalikos JF, Orgill DP. Reply: Mechanisms of action of external volume expansion devices. Plast Reconstr Surg. 2014 Mar; 133(3):426e-428e. PMID: 24572895.
    Citations:    Fields:    Translation:Animals
  111. Gobble RM, Hoang HL, Kachniarz B, Orgill DP. Ketorolac does not increase perioperative bleeding: a meta-analysis of randomized controlled trials. Plast Reconstr Surg. 2014 Mar; 133(3):741-55. PMID: 24572864.
    Citations: 16     Fields:    Translation:Humans
  112. Chen YE, Gerstle T, Verma K, Treiser MD, Kimball AB, Orgill DP. Management of hidradenitis suppurativa wounds with an internal vacuum-assisted closure device. Plast Reconstr Surg. 2014 Mar; 133(3):370e-377e. PMID: 24572882.
    Citations: 3     Fields:    Translation:Humans
  113. Orgill DP, Ogawa R. Discussion: the embrace device significantly decreases scarring following scar revision surgery in a randomized controlled trial. Plast Reconstr Surg. 2014 Feb; 133(2):406-7. PMID: 24469172.
    Citations: 1     Fields:    Translation:Humans
  114. Maruthappu M, Carty MJ, Lipsitz SR, Wright J, Orgill D, Duclos A. Patient- and surgeon-adjusted control charts for monitoring performance. BMJ Open. 2014 Jan 16; 4(1):e004046. PMID: 24440796; PMCID: PMC3902330.
    Citations: 2     Fields:    Translation:Humans
  115. Douaiher J, Succar J, Lancerotto L, Gurish MF, Orgill DP, Hamilton MJ, Krilis SA, Stevens RL. Development of mast cells and importance of their tryptase and chymase serine proteases in inflammation and wound healing. Adv Immunol. 2014; 122:211-52. PMID: 24507159; PMCID: PMC4115062.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  116. Xu R, Carty MJ, Orgill DP, Lipsitz SR, Duclos A. The teaming curve: a longitudinal study of the influence of surgical team familiarity on operative time. Ann Surg. 2013 Dec; 258(6):953-7. PMID: 23407297.
    Citations: 15     Fields:    Translation:Humans
  117. Orgill DP, Bayer LR. Negative pressure wound therapy: past, present and future. Int Wound J. 2013 Dec; 10 Suppl 1:15-9. PMID: 24251839.
    Citations: 12     Fields:    Translation:Humans
  118. Carty MJ, Caterson EJ, Caterson SA, Chun YS, Erdmann-Sager J, Hadad I, Halvorson EG, Orgill DP, Sampson CE, Talbot SG, Theman T, Eriksson E. Why we are here: early reflections on the role of reconstructive plastic surgery in the 2013 Boston marathon bombings. Plast Reconstr Surg. 2013 Dec; 132(6):1623-7. PMID: 24281588.
    Citations: 1     Fields:    Translation:Humans
  119. Vyas RM, Orgill DP. Reply: transdiaphragmatic omental harvest: a simple, efficient method for sternal wound coverage. Plast Reconstr Surg. 2013 Dec; 132(6):1074e. PMID: 24281620.
    Citations:    Fields:    Translation:Humans
  120. Kim PJ, Attinger CE, Steinberg JS, Evans KK, Lehner B, Willy C, Lavery L, Wolvos T, Orgill D, Ennis W, Lantis J, Gabriel A, Schultz G. Negative-pressure wound therapy with instillation: international consensus guidelines. Plast Reconstr Surg. 2013 Dec; 132(6):1569-79. PMID: 24005370.
    Citations: 4     Fields:    Translation:Humans
  121. Heit YI, Lancerotto L, Cortes R, Mesteri I, Ackermann M, Hollander R, Li Q, Douaiher J, Konerding MA, Orgill DP. Early kinetics of integration of collagen-glycosaminoglycan regenerative scaffolds in a diabetic mouse model. Plast Reconstr Surg. 2013 Nov; 132(5):767e-776e. PMID: 24165628.
    Citations: 3     Fields:    Translation:Animals
  122. Agha RA, Camm CF, Doganay E, Edison E, Siddiqui MR, Orgill DP. Randomised controlled trials in plastic surgery: a systematic review of reporting quality. Eur J Plast Surg. 2014; 37:55-62. PMID: 24707112.
    Citations: 4     
  123. Agha RA, Goodacre T, Orgill DP. Use of autologous fat grafting for reconstruction postmastectomy and breast conserving surgery: a systematic review protocol. BMJ Open. 2013 Oct 22; 3(10):e003709. PMID: 24154518; PMCID: PMC3808755.
    Citations: 5     Fields: