Harvard Catalyst Profiles

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Dennis Paul Orgill, M.D., Ph.D.

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Mentoring
Wound Healing Study[login at prompt]
Available: 10/11/18, Expires: 02/01/21

"

You will join one of the main areas of investigation in our lab (advanced scaffold-based tissue engineering, diabetic wound healing, modulation of soft tissue regeneration, mechanobiology of wound healing) and will be supported in the drafting/proposal of a comprehensive research plan related to innovative strategies for therapeutic wound healing and induction of tissue regeneration in pre-clinical models and in vitro. As a member of a lab uniquely encompassing translational model-based investigations as well as clinical outcomes-based studies, students will have ample and diverse opportunities to find and pursue projects customized to their interests.

Students will be participating in all aspects of the research process, including but not limited to familiarization with and critical appraisal of the literature, application of sound scientific methodology, development of a research plan, drafting of experimental protocols for funding applications, and driving the data toward research publications. They will be taught hands-on pre-clinical techniques as well as histological processing and staining methods.

Our research program fosters a highly collaborative, interdisciplinary environment in which students can work with many investigators and labs (muscle regeneration, vascular surgery, general surgery, dermatology, orthopedics, diabetes, transplantation surgery, cell biology) in the surrounding region. Lab meetings are held weekly where students can share the progress of their research and hear updates on projects by fellow researchers.

Main ongoing investigations include but are not limited to:

  1. Application of a murine diabetic chronic wound model to test and investigate novel wound healing therapeutics
  2. Investigation of the effects of negative pressure wound therapy (and other mechanical forces) on inflammatory lymphangiogenesis
  3. Investigation of full-thickness “micrografts” and other novel techniques in diabetic murine models.
"

Accelerated Regenerative Wound Healing with a Microarray Chamber Device and the Addition of Keratinocytes
Summer, 02/02/10 - 08/20/10

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Giatsidis G, Succar J, Waters TD, Liu W, Rhodius P, Chnari E, Orgill DP. Reply: Tissue-Engineered Soft-Tissue Reconstruction Using Noninvasive Mechanical Preconditioning and a Shelf-Ready Allograft Adipose Matrix. Plast Reconstr Surg. 2020 Jul; 146(1):99e-100e. PMID: 32590678.
    Citations:    
  2. Hamaguchi R, Francis AM, Kramer KM, Lian CG, O'Leary MP, Orgill DP. Grand Rounds: Multimodal Surgical Management of Severe Scrotal Lymphedema and Buried Penis. Urology. 2020 Jun 25. PMID: 32593626.
    Citations:    
  3. Kim PJ, Lavery LA, Galiano RD, Salgado CJ, Orgill DP, Kovach SJ, Bernstein BH, Attinger CE. The impact of negative-pressure wound therapy with instillation on wounds requiring operative debridement: Pilot randomised, controlled trial. Int Wound J. 2020 Jun 21. PMID: 32567234.
    Citations:    
  4. Armstrong DG, Orgill DP, Galiano R, Glat PM, Carter M, Zelen CM, Li WW. Complete wound closure following a single topical application of a novel autologous homologous skin construct: first evaluation in an open-label, single-arm feasibility study in diabetic foot ulcers. Int Wound J. 2020 May 26. PMID: 32453512.
    Citations:    
  5. Irwin TJ, Orgill D. Closed Incision Negative Pressure Wound Therapy After Resection of Large, Radiated, Soft Tissue Sarcomas. Cureus. 2020 May 11; 12(5):e8055. PMID: 32537273.
    Citations:    
  6. Armstrong DG, Orgill DP, Galiano RD, Glat PM, Kaufman JP, Carter MJ, Zelen CM. An observational pilot study using a purified reconstituted bilayer matrix to treat non-healing diabetic foot ulcers. Int Wound J. 2020 Aug; 17(4):966-973. PMID: 32266774.
    Citations:    
  7. Climov M, Panayi AC, Borah G, Orgill DP. The life-cycles of skin replacement technologies. PLoS One. 2020; 15(3):e0229455. PMID: 32130238.
    Citations:    
  8. Loretelli C, Ben Nasr M, Giatsidis G, Bassi R, Lancerotto L, D'Addio F, Valderrama-Vasquez A, Scherer SS, Salvatore L, Madaghiele M, Abdelsalam A, Ippolito E, Assi E, Usuelli V, El Essawy B, Sannino A, Pietramaggiori G, Zuccotti GV, Orgill DP, Fiorina P. Embryonic stem cell extracts improve wound healing in diabetic mice. Acta Diabetol. 2020 Jul; 57(7):883-890. PMID: 32124076.
    Citations:    
  9. An Y, Panayi AC, Mi B, Fu S, Orgill DP. Comparative Analysis of Two Automated Fat-processing Systems. Plast Reconstr Surg Glob Open. 2020 Jan; 8(1):e2587. PMID: 32095398.
    Citations:    
  10. Icli B, Li H, Pérez-Cremades D, Wu W, Ozdemir D, Haemmig S, Guimaraes RB, Manica A, Marchini JF, Orgill DP, Feinberg MW. MiR-4674 regulates angiogenesis in tissue injury by targeting p38K signaling in endothelial cells. Am J Physiol Cell Physiol. 2020 03 01; 318(3):C524-C535. PMID: 31913696.
    Citations:    
  11. Gfrerer L, Orgill DP. Discussion: Increasing Fat Graft Retention in Irradiated Tissue after Preconditioning with External Volume Expansion. Plast Reconstr Surg. 2020 01; 145(1):113-114. PMID: 31881611.
    Citations:    
  12. Orgill DP, Wei S, Gundogan B, Giatsidis G. Reply: Delayed Postconditioning with External Volume Expansion Improves Survival of Adipose Tissue Grafts in a Murine Model. Plast Reconstr Surg. 2020 01; 145(1):204e. PMID: 31834227.
    Citations:    
  13. Panayi AC, Smit L, Hays N, Udeh K, Endo Y, Li B, Sakthivel D, Tamayol A, Neppl RL, Orgill DP, Nuutila K, Sinha I. A porous collagen-GAG scaffold promotes muscle regeneration following volumetric muscle loss injury. Wound Repair Regen. 2020 01; 28(1):61-74. PMID: 31603580.
    Citations:    
  14. Agha R, Abdall-Razak A, Crossley E, Dowlut N, Iosifidis C, Mathew G. STROCSS 2019 Guideline: Strengthening the reporting of cohort studies in surgery. Int J Surg. 2019 Dec; 72:156-165. PMID: 31704426.
    Citations:    
  15. Orgill DP. Reply: Delayed Postconditioning with External Volume Expansion Improves Survival of Adipose Tissue Grafts in a Murine Model. Plast Reconstr Surg. 2019 10; 144(4):714e. PMID: 31568335.
    Citations:    
  16. Giatsidis G, Succar J, Waters TD, Liu W, Rhodius P, Wang C, Nilsen TJ, Chnari E, Orgill DP. Tissue-Engineered Soft-Tissue Reconstruction Using Noninvasive Mechanical Preconditioning and a Shelf-Ready Allograft Adipose Matrix. Plast Reconstr Surg. 2019 10; 144(4):884-895. PMID: 31568297.
    Citations:    
  17. Glat P, Orgill DP, Galiano R, Armstrong D, Serena T, DiDomenico LA, Kaufman J, Carter MJ, Jacobs AM, Zelen CM. Placental Membrane Provides Improved Healing Efficacy and Lower Cost Versus a Tissue-Engineered Human Skin in the Treatment of Diabetic Foot Ulcerations. Plast Reconstr Surg Glob Open. 2019 Aug; 7(8):e2371. PMID: 31592387.
    Citations:    
  18. Succar J, Giatsidis G, Yu N, Hassan K, Khouri R, Gurish MF, Pejler G, Åbrink M, Orgill DP. Mouse Mast Cell Protease-4 Recruits Leukocytes in the Inflammatory Phase of Surgically Wounded Skin. Adv Wound Care (New Rochelle). 2019 Oct 01; 8(10):469-475. PMID: 31456904.
    Citations:    
  19. Giatsidis G, Succar J, Waters TD, Liu W, Rhodius P, Wang C, Nilsen TJ, Chnari E, Orgill DP. Tissue Engineered Soft Tissue Reconstruction Using Non-invasive Mechanical Preconditioning and a Shelf-ready Allograft Adipose Matrix. Plast Reconstr Surg. 2019 Jul 03. PMID: 31299681.
    Citations:    
  20. Christensen JM, Orgill DP. Discussion: The Interplay of Mechanical Stress, Strain, and Stiffness at the Keloid Periphery Correlates with Increased Caveolin-1/ROCK Signaling and Scar Progression. Plast Reconstr Surg. 2019 07; 144(1):68e-69e. PMID: 31246820.
    Citations:    
  21. Orgill DP. Response to Drs. Hua and Wei. Plast Reconstr Surg. 2019 Jul 01. PMID: 31274764.
    Citations:    
  22. Icli B, Wu W, Ozdemir D, Li H, Cheng HS, Haemmig S, Liu X, Giatsidis G, Avci SN, Lee N, Guimaraes RB, Manica A, Marchini JF, Rynning SE, Risnes I, Hollan I, Croce K, Yang X, Orgill DP, Feinberg MW. MicroRNA-615-5p Regulates Angiogenesis and Tissue Repair by Targeting AKT/eNOS (Protein Kinase B/Endothelial Nitric Oxide Synthase) Signaling in Endothelial Cells. Arterioscler Thromb Vasc Biol. 2019 07; 39(7):1458-1474. PMID: 31092013.
    Citations:    
  23. Sood RF, Orgill DP. Discussion: An Assessment of Bleeding Complications Necessitating Blood Transfusion across Inpatient Plastic Surgery Procedures: A Nationwide Analysis Using the National Surgical Quality Improvement Program Database. Plast Reconstr Surg. 2019 05; 143(5):1118e-1119e. PMID: 31033842.
    Citations:    
  24. Uehara M, Li X, Sheikhi A, Zandi N, Walker B, Saleh B, Banouni N, Jiang L, Ordikhani F, Dai L, Yonar M, Vohra I, Kasinath V, Orgill DP, Khademhosseini A, Annabi N, Abdi R. Anti-IL-6 eluting immunomodulatory biomaterials prolong skin allograft survival. Sci Rep. 2019 04 25; 9(1):6535. PMID: 31024011.
    Citations:    
  25. Kim PJ, Attinger CE, Orgill D, Galiano RD, Steinberg JS, Evans KK, Lavery LA. Complex Lower Extremity Wound in the Complex Host: Results From a Multicenter Registry. Plast Reconstr Surg Glob Open. 2019 Apr; 7(4):e2129. PMID: 31321165.
    Citations:    
  26. Taylor EM, Orgill DP. Discussion: Quality and Quantity-Cultured Murine Endothelial Progenitor Cells Increase Vascularization and Decrease Fibrosis in the Fat Graft. Plast Reconstr Surg. 2019 04; 143(4):756e-757e. PMID: 30921124.
    Citations:    
  27. Roh DS, Orgill DP. Discussion: The Preparation of the Recipient Site in Fat Grafting: A Comprehensive Review of the Preclinical Evidence. Plast Reconstr Surg. 2019 04; 143(4):1108-1110. PMID: 30921130.
    Citations:    
  28. Tappenbeck N, Schröder HM, Niebergall-Roth E, Hassinger F, Dehio U, Dieter K, Kraft K, Kerstan A, Esterlechner J, Frank NY, Scharffetter-Kochanek K, Murphy GF, Orgill DP, Beck J, Frank MH, Ganss C, Kluth MA. In vivo safety profile and biodistribution of GMP-manufactured human skin-derived ABCB5-positive mesenchymal stromal cells for use in clinical trials. Cytotherapy. 2019 05; 21(5):546-560. PMID: 30878384.
    Citations:    
  29. Alikhan A, Sayed C, Alavi A, Alhusayen R, Brassard A, Burkhart C, Crowell K, Eisen DB, Gottlieb AB, Hamzavi I, Hazen PG, Jaleel T, Kimball AB, Kirby J, Lowes MA, Micheletti R, Miller A, Naik HB, Orgill D, Poulin Y. North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part II: Topical, intralesional, and systemic medical management. J Am Acad Dermatol. 2019 Jul; 81(1):91-101. PMID: 30872149.
    Citations:    
  30. Alikhan A, Sayed C, Alavi A, Alhusayen R, Brassard A, Burkhart C, Crowell K, Eisen DB, Gottlieb AB, Hamzavi I, Hazen PG, Jaleel T, Kimball AB, Kirby J, Lowes MA, Micheletti R, Miller A, Naik HB, Orgill D, Poulin Y. North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: Diagnosis, evaluation, and the use of complementary and procedural management. J Am Acad Dermatol. 2019 Jul; 81(1):76-90. PMID: 30872156.
    Citations:    
  31. Liu Y, Xu S, Zu T, Li F, Sang S, Liu C, An Y, Mi B, Orgill DP, Murphy GF, Lian CG. Reversal of TET-mediated 5-hmC loss in hypoxic fibroblasts by ascorbic acid. Lab Invest. 2019 07; 99(8):1193-1202. PMID: 30837678.
    Citations:    
  32. Wei S, Orgill DP, Giatsidis G. Delivery of External Volume Expansion through Microdeformational Interfaces Safely Induces Angiogenesis in a Murine Model of Intact Diabetic Skin with Endothelial Cell Dysfunction. Plast Reconstr Surg. 2019 02; 143(2):453-464. PMID: 30531623.
    Citations:    Fields:    
  33. Icli B, Wu W, Ozdemir D, Li H, Haemmig S, Liu X, Giatsidis G, Cheng HS, Avci SN, Kurt M, Lee N, Guimaraes RB, Manica A, Marchini JF, Rynning SE, Risnes I, Hollan I, Croce K, Orgill DP, Feinberg MW. MicroRNA-135a-3p regulates angiogenesis and tissue repair by targeting p38 signaling in endothelial cells. FASEB J. 2019 04; 33(4):5599-5614. PMID: 30668922.
    Citations:    Fields:    
  34. Roh DS, Panayi AC, Bhasin S, Orgill DP, Sinha I. Implications of Aging in Plastic Surgery. Plast Reconstr Surg Glob Open. 2019 Jan; 7(1):e2085. PMID: 30859042.
    Citations:    
  35. Contessi Negrini N, Bonnetier M, Giatsidis G, Orgill DP, Farè S, Marelli B. Tissue-mimicking gelatin scaffolds by alginate sacrificial templates for adipose tissue engineering. Acta Biomater. 2019 03 15; 87:61-75. PMID: 30654214.
    Citations:    Fields:    
  36. Liu Y, Panayi AC, Bayer LR, Orgill DP. Current Available Cellular and Tissue-Based Products for Treatment of Skin Defects. Adv Skin Wound Care. 2019 Jan; 32(1):19-25. PMID: 30570555.
    Citations:    Fields:    
  37. Gabriel A, Gupta S, Orgill DP. Challenges and Management of Surgical Site Occurrences. Plast Reconstr Surg. 2019 01; 143(1S Management of Surgical Incisions Utilizing Closed-Incision Negative-Pressure Therapy):7S-10S. PMID: 30586096.
    Citations:    Fields:    
  38. Arnold PB, Orgill DP. Discussion: Is Reconstruction Preserving the First Ray or First Two Rays Better Than Full Transmetatarsal Amputation in Diabetic Foot? Plast Reconstr Surg. 2019 01; 143(1):306-307. PMID: 30589806.
    Citations:    Fields:    
  39. Gabriel A, Maxwell GP, Orgill DP. Introduction to "Management of Surgical Incisions Utilizing Closed-Incision Negative-Pressure Therapy". Plast Reconstr Surg. 2019 01; 143(1S Management of Surgical Incisions Utilizing Closed-Incision Negative-Pressure Therapy):4S-5S. PMID: 30586095.
    Citations:    Fields:    
  40. Panayi AC, Orgill DP. Current Use of Biological Scaffolds in Plastic Surgery. Plast Reconstr Surg. 2019 01; 143(1):209-220. PMID: 30286046.
    Citations:    Fields:    
  41. Wei S, Liu W, Gundogan B, Moscoso AV, Orgill DP, Giatsidis G. Delayed Postconditioning with External Volume Expansion Improves Survival of Adipose Tissue Grafts in a Murine Model. Plast Reconstr Surg. 2019 01; 143(1):99e-110e. PMID: 30325898.
    Citations:    Fields:    
  42. Agha RA, Al Omran Y, Wellstead G, Sagoo H, Barai I, Rajmohan S, Borrelli MR, Vella-Baldacchino M, Orgill DP, Rusby JE. Systematic review of therapeutic nipple-sparing versus skin-sparing mastectomy. BJS Open. 2019 04; 3(2):135-145. PMID: 30957059.
    Citations:    
  43. Rhodius P, Haddad A, Matsumine H, Sakthivel D, Ackermann M, Sinha I, Orgill DP, Giatsidis G. Noninvasive Flap Preconditioning by Foam-Mediated External Suction Improves the Survival of Fasciocutaneous Axial-Pattern Flaps in a Type 2 Diabetic Murine Model. Plast Reconstr Surg. 2018 12; 142(6):872e-883e. PMID: 30188471.
    Citations:    Fields:    
  44. Panayi AC, Orkaby AR, Sakthivel D, Endo Y, Varon D, Roh D, Orgill DP, Neppl RL, Javedan H, Bhasin S, Sinha I. Impact of frailty on outcomes in surgical patients: A systematic review and meta-analysis. Am J Surg. 2019 08; 218(2):393-400. PMID: 30509455.
    Citations:    Fields:    
  45. Agha RA, Borrelli MR, Farwana R, Koshy K, Fowler AJ, Orgill DP. The PROCESS 2018 statement: Updating Consensus Preferred Reporting Of CasE Series in Surgery (PROCESS) guidelines. Int J Surg. 2018 Dec; 60:279-282. PMID: 30359781.
    Citations:    Fields:    
  46. Agha RA, Borrelli MR, Farwana R, Koshy K, Fowler AJ, Orgill DP. The SCARE 2018 statement: Updating consensus Surgical CAse REport (SCARE) guidelines. Int J Surg. 2018 Dec; 60:132-136. PMID: 30342279.
    Citations:    Fields:    
  47. Giatsidis G, Succar J, Haddad A, Lago G, Schaffer C, Wang X, Schilling B, Chnari E, Matsumine H, Orgill DP. Preclinical Optimization of a Shelf-Ready, Injectable, Human-Derived, Decellularized Allograft Adipose Matrix. Tissue Eng Part A. 2019 02; 25(3-4):271-287. PMID: 30084731.
    Citations:    Fields:    
  48. Aycart MA, Eble DJ, Ross KM, Orgill DP. Mechanisms of Action of Instillation and Dwell Negative Pressure Wound Therapy with Case Reports of Clinical Applications. Cureus. 2018 Sep 27; 10(9):e3377. PMID: 30524912.
    Citations:    
  49. Mella JR, Ross KM, Li GZ, Pomahac B, Raut CP, Orgill DP. Cutaneous Breast Radiation-associated Angiosarcoma: Anterior Chest Wall Reconstruction Options Following Extra-radical Resection. Plast Reconstr Surg Glob Open. 2018 Sep; 6(9):e1938. PMID: 30349797.
    Citations:    
  50. DiDomenico LA, Orgill DP, Galiano RD, Serena TE, Carter MJ, Kaufman JP, Young NJ, Jacobs AM, Zelen CM. Use of an aseptically processed, dehydrated human amnion and chorion membrane improves likelihood and rate of healing in chronic diabetic foot ulcers: A prospective, randomised, multi-centre clinical trial in 80 patients. Int Wound J. 2018 Dec; 15(6):950-957. PMID: 30019528.
    Citations:    Fields:    
  51. Giatsidis G, Guyette JP, Ott HC, Orgill DP. Development of a large-volume human-derived adipose acellular allogenic flap by perfusion decellularization. Wound Repair Regen. 2018 03; 26(2):245-250. PMID: 29617055.
    Citations:    Fields:    
  52. Agha RA, Pidgeon TE, Borrelli MR, Dowlut N, Orkar TK, Ahmed M, Pujji O, Orgill DP. Validated Outcomes in the Grafting of Autologous Fat to the Breast: The VOGUE Study. Development of a Core Outcome Set for Research and Audit. Plast Reconstr Surg. 2018 05; 141(5):633e-638e. PMID: 29697603.
    Citations:    Fields:    Translation:Humans
  53. Zelen CM, Orgill DP, Serena TE, Galiano RE, Carter MJ, DiDomenico LA, Keller J, Kaufman JP, Li WW. An aseptically processed, acellular, reticular, allogenic human dermis improves healing in diabetic foot ulcers: A prospective, randomised, controlled, multicentre follow-up trial. Int Wound J. 2018 Oct; 15(5):731-739. PMID: 29682897.
    Citations:    Fields:    Translation:Humans
  54. Wang C, Luan J, Panayi AC, Orgill DP, Xin M. Complications in breast augmentation with textured versus smooth breast implants: a systematic review protocol. BMJ Open. 2018 04 10; 8(4):e020671. PMID: 29643164.
    Citations:    Fields:    
  55. Heit YI, Orgill DP. Discussion: External Volume Expansion Up-Regulates CXCL12 Expression and Enhances Mesenchymal Stromal Cell Recruitment toward Expanded Prefabricated Adipose Tissue in Rats. Plast Reconstr Surg. 2018 04; 141(4):538e-539e. PMID: 29595729.
    Citations:    Fields:    Translation:AnimalsCells
  56. Ross KM, Moscoso AV, Bayer LR, Rosselli-Risal L, Orgill DP. Plastic Surgery Complications from Medical Tourism Treated in a U.S. Academic Medical Center. Plast Reconstr Surg. 2018 04; 141(4):517e-523e. PMID: 29595725.
    Citations:    Fields:    Translation:Humans
  57. Panayi AC, Agha RA, Sieber BA, Orgill DP. Impact of Obesity on Outcomes in Breast Reconstruction: A Systematic Review and Meta-Analysis. J Reconstr Microsurg. 2018 Jun; 34(5):363-375. PMID: 29510420.
    Citations:    Fields:    Translation:Humans
  58. Thorlacius L, Garg A, Ingram JR, Villumsen B, Theut Riis P, Gottlieb AB, Merola JF, Dellavalle R, Ardon C, Baba R, Bechara FG, Cohen AD, Daham N, Davis M, Emtestam L, Fernández-Peñas P, Filippelli M, Gibbons A, Grant T, Guilbault S, Gulliver S, Harris C, Harvent C, Houston K, Kirby JS, Matusiak L, Mehdizadeh A, Mojica T, Okun M, Orgill D, Pallack L, Parks-Miller A, Prens EP, Randell S, Rogers C, Rosen CF, Choon SE, van der Zee HH, Christensen R, Jemec GBE. Towards global consensus on core outcomes for hidradenitis suppurativa research: an update from the HISTORIC consensus meetings I and II. Br J Dermatol. 2018 03; 178(3):715-721. PMID: 29080368.
    Citations: 1     Fields:    
  59. Roh DS, Orgill DP. Discussion: Early Macrophage Infiltration Improves Fat Graft Survival by Inducing Angiogenesis and Hematopoietic Stem Cell Recruitment. Plast Reconstr Surg. 2018 02; 141(2):387-388. PMID: 29369989.
    Citations:    Fields:    Translation:HumansCells
  60. Ogawa R, Daya M, Orgill DP. Discussion: Percutaneous Mesh Expansion: A Regenerative Wound Closure Alternative. Plast Reconstr Surg. 2018 02; 141(2):458-459. PMID: 29369998.
    Citations:    Fields:    Translation:Humans
  61. Sinha I, Giatsidis G, Orgill DP. Discussion: Protective Effect of Hydrogen Gas Inhalation on Muscular Damage Using a Mouse Hindlimb Ischemia-Reperfusion Injury Model. Plast Reconstr Surg. 2017 12; 140(6):1207-1208. PMID: 29176415.
    Citations:    Fields:    
  62. Giatsidis G, Cheng L, Haddad A, Ji K, Succar J, Lancerotto L, Lujan-Hernandez J, Fiorina P, Matsumine H, Orgill DP. Noninvasive induction of angiogenesis in tissues by external suction: sequential optimization for use in reconstructive surgery. Angiogenesis. 2018 02; 21(1):61-78. PMID: 29147813.
    Citations:    Fields:    
  63. Sîrbulescu RF, Boehm CK, Soon E, Wilks MQ, Ilies I, Yuan H, Maxner B, Chronos N, Kaittanis C, Normandin MD, El Fakhri G, Orgill DP, Sluder AE, Poznansky MC. Mature B cells accelerate wound healing after acute and chronic diabetic skin lesions. Wound Repair Regen. 2017 09; 25(5):774-791. PMID: 28922523.
    Citations: 2     Fields:    Translation:AnimalsCells
  64. Agha RA, Borrelli MR, Vella-Baldacchino M, Thavayogan R, Orgill DP. The STROCSS statement: Strengthening the Reporting of Cohort Studies in Surgery. Int J Surg. 2017 Oct; 46:198-202. PMID: 28890409.
    Citations: 37     Fields:    Translation:Humans
  65. Agha RA, Fowler AJ, Saeta A, Barai I, Rajmohan S, Orgill DP. Erratum to "Erratum to "The SCARE guidelines: Consensus-based surgical case report guidelines" [Int. J. Surg. 34 (2016) 180-186]" [Int. J. Surg. 36 (2016) 396]. Int J Surg. 2017 11; 47:151. PMID: 28847721.
    Citations: 1     Fields:    
  66. Agha RA, Borrelli MR, Dowlut N, Butt MF, Freeman S, Orkar TE, Orgill DP. Use of autologous fat grafting in reconstruction following mastectomy and breast conserving surgery: An updated systematic review protocol. Int J Surg Protoc. 2017; 5:22-26. PMID: 31851753.
    Citations:    
  67. Agha RA, Borrelli MR, Vella-Baldacchino M, Thavayogan R, Orgill DP. A protocol for the development of the STROCSS guideline: Strengthening the Reporting of Cohort Studies in Surgery. Int J Surg Protoc. 2017; 5:15-17. PMID: 31851747.
    Citations:    
  68. Agha RA, Borrelli MR, Farwana R, Kusu-Orkar T, Millip MC, Thavayogan R, Garner J, Darhouse N, Orgill DP. Impact of the PROCESS guideline on the reporting of surgical case series: A before and after study. Int J Surg. 2017 Sep; 45:92-97. PMID: 28760706.
    Citations: 2     Fields:    Translation:Humans
  69. Agha RA, Farwana R, Borrelli MR, Tickunas T, Kusu-Orkar T, Millip MC, Thavayogan R, Garner J, Orgill DP. Impact of the SCARE guideline on the reporting of surgical case reports: A before and after study. Int J Surg. 2017 Sep; 45:144-148. PMID: 28757396.
    Citations: 3     Fields:    Translation:Humans
  70. DiDomenico LA, Orgill DP, Galiano RD, Serena TE, Carter MJ, Kaufman JP, Young NJ, Zelen CM. A Retrospective Crossover Study of the Use of Aseptically Processed Placental Membrane in the Treatment of Chronic Diabetic Foot Ulcers. Wounds. 2017 10; 29(10):311-316. PMID: 28873060.
    Citations:    Fields:    
  71. Seth AK, Friedstat JS, Orgill DP, Pribaz JJ, Halvorson EG. Microsurgical Burn Reconstruction. Clin Plast Surg. 2017 Oct; 44(4):823-832. PMID: 28888307.
    Citations:    Fields:    Translation:Humans
  72. Szabo Eltorai A, Huang CC, Lu JT, Ogura A, Caterson SA, Orgill DP. Selective Intraoperative Vasopressor Use Is Not Associated with Increased Risk of DIEP Flap Complications. Plast Reconstr Surg. 2017 Jul; 140(1):70e-77e. PMID: 28654605.
    Citations:    Fields:    Translation:Humans
  73. Agha RA, Barai I, Rajmohan S, Lee S, Anwar MO, Fowler AJ, Orgill DP, Altman DG. Support for reporting guidelines in surgical journals needs improvement: A systematic review. Int J Surg. 2017 Sep; 45:14-17. PMID: 28673865.
    Citations: 4     Fields:    Translation:Humans
  74. Pidgeon TE, Limb C, Agha RA, Whitehurst K, Chandrakumar C, Wellstead G, Fowler AJ, Orgill DP. The use of study registration and protocols in plastic surgery research: A systematic review. Int J Surg. 2017 Aug; 44:215-222. PMID: 28625821.
    Citations:    Fields:    Translation:Humans
  75. Chin MS, Chappell AG, Giatsidis G, Perry DJ, Lujan-Hernandez J, Haddad A, Matsumine H, Orgill DP, Lalikos JF. Hyperspectral Imaging Provides Early Prediction of Random Axial Flap Necrosis in a Preclinical Model. Plast Reconstr Surg. 2017 Jun; 139(6):1285e-1290e. PMID: 28538567.
    Citations:    Fields:    Translation:Animals
  76. Giatsidis G, Cheng L, Facchin F, Haddad A, Lujan-Hernandez J, Lancerotto L, Nabzdyk CG, Matsumine H, Orgill DP. Moderate-Intensity Intermittent External Volume Expansion Optimizes the Soft-Tissue Response in a Murine Model. Plast Reconstr Surg. 2017 Apr; 139(4):882-890. PMID: 28350665.
    Citations: 2     Fields:    Translation:Animals
  77. Haddad AG, Giatsidis G, Orgill DP, Halvorson EG. Skin Substitutes and Bioscaffolds: Temporary and Permanent Coverage. Clin Plast Surg. 2017 Jul; 44(3):627-634. PMID: 28576252.
    Citations:    Fields:    Translation:Humans
  78. Li GZ, Fairweather M, Wang J, Orgill DP, Bertagnolli MM, Raut CP. Cutaneous Radiation-associated Breast Angiosarcoma: Radicality of Surgery Impacts Survival. Ann Surg. 2017 04; 265(4):814-820. PMID: 28267696.
    Citations: 2     Fields:    Translation:Humans
  79. Matsumine H, Numakura K, Tsunoda S, Wang H, Matsumine R, Climov M, Giatsidis G, Sukhatme VP, Orgill DP. Adipose-derived aldehyde dehydrogenase-expressing cells promote dermal regenerative potential with collagen-glycosaminoglycan scaffold. Wound Repair Regen. 2017 01; 25(1):109-119. PMID: 28230922.
    Citations: 1     Fields:    Translation:AnimalsCells
  80. Zelen CM, Orgill DP, Serena TE, Galiano RD, Carter MJ, DiDomenico LA, Kaufman JP, Keller J, Young NJ, Li WW. Human Reticular Acellular Dermal Matrix in the Healing of Chronic Diabetic Foot Ulcerations that Failed Standard Conservative Treatment: A Retrospective Crossover Study. Wounds. 2017 Feb; 29(2):39-45. PMID: 28272011.
    Citations: 1     Fields:    Translation:Humans
  81. Cheng L, Ji K, Shih TY, Haddad A, Giatsidis G, Mooney DJ, Orgill DP, Nabzdyk CS. Injectable Shape-Memorizing Three-Dimensional Hyaluronic Acid Cryogels for Skin Sculpting and Soft Tissue Reconstruction. Tissue Eng Part A. 2017 03; 23(5-6):243-251. PMID: 27875939.
    Citations: 1     Fields:    Translation:Animals
  82. Ricci JA, Bayer LR, Orgill DP. Evidence-Based Medicine: The Evaluation and Treatment of Pressure Injuries. Plast Reconstr Surg. 2017 Jan; 139(1):275e-286e. PMID: 28027261.
    Citations: 2     Fields:    Translation:Humans
  83. Agha RA, Fowler AJ, Saeta A, Barai I, Rajmohan S, Orgill DP. Erratum to "The SCARE guidelines: Consensus-based surgical case report guidelines" [Int. J. Surg. 34 (2016) 180-186]. Int J Surg. 2016 12; 36(Pt A):396. PMID: 27851898.
    Citations: 8     Fields:    
  84. Agha RA, Fowler AJ, Pidgeon TE, Wellstead G, Orgill DP. The Need for Core Outcome Reporting in Autologous Fat Grafting for Breast Reconstruction. Ann Plast Surg. 2016 Nov; 77(5):506-512. PMID: 26545226.
    Citations: 3     Fields:    Translation:Humans
  85. Agha RA, Fowler AJ, Rajmohan S, Barai I, Orgill DP. Preferred reporting of case series in surgery; the PROCESS guidelines. Int J Surg. 2016 Dec; 36(Pt A):319-323. PMID: 27770639.
    Citations: 126     Fields:    Translation:Humans
  86. DiDomenico LA, Orgill DP, Galiano RD, Serena TE, Carter MJ, Kaufman JP, Young NJ, Zelen CM. Aseptically Processed Placental Membrane Improves Healing of Diabetic Foot Ulcerations: Prospective, Randomized Clinical Trial. Plast Reconstr Surg Glob Open. 2016 Oct; 4(10):e1095. PMID: 27826487.
    Citations: 3     
  87. Panayi A, Agha RA, Sieber BA, Orgill DP. Impact of obesity on outcomes in breast reconstruction: A systematic review protocol. Int J Surg Protoc. 2016; 2:1-4. PMID: 31897447.
    Citations:    
  88. Dasgupta A, Orgill D, Galiano RD, Zelen CM, Huang YC, Chnari E, Li WW. A Novel Reticular Dermal Graft Leverages Architectural and Biological Properties to Support Wound Repair. Plast Reconstr Surg Glob Open. 2016 Oct; 4(10):e1065. PMID: 27826469.
    Citations:    
  89. Lujan-Hernandez J, Lancerotto L, Nabzdyk C, Hassan KZ, Giatsidis G, Khouri RK, Chin MS, Bassetto F, Lalikos JF, Orgill DP. Reply: Induction of Adipogenesis by External Volume Expansion. Plast Reconstr Surg. 2016 10; 138(4):770e-2e. PMID: 27307329.
    Citations:    Fields:    Translation:HumansCells
  90. Najjar PA, Madenci AL, Zogg CK, Schneider EB, Dankers CA, Pimentel MT, Chabria AS, Goldberg JE, Sharma G, Piazza G, Bleday R, Orgill DP, Kachalia A. Implementation of a Comprehensive Post-Discharge Venous Thromboembolism Prophylaxis Program for Abdominal and Pelvic Surgery Patients. J Am Coll Surg. 2016 12; 223(6):804-813. PMID: 27693288.
    Citations:    Fields:    Translation:Humans
  91. Agha R, Fowler AJ, Limb C, Al Omran Y, Sagoo H, Koshy K, Jafree DJ, Anwar MO, McCullogh P, Orgill DP. The First 500 Registrations to the Research Registry®: Advancing Registration of Under-Registered Study Types. Front Surg. 2016; 3:50. PMID: 27695693.