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Dennis Paul Orgill, M.D., PH.D.

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Mentoring
Wound Healing Study[login at prompt]
Available: 10/11/18, Expires: 10/01/20

You will join one of the main areas of investigation in our lab (Advanced scaffolds tissue engineering, Diabetic wound healing, Modulation of soft tissue regeneration, Healing through mechanical forces) and will be supported in the drafting/proposal of a comprehensive research plan related to innovative strategies for therapeutic wound healing and induction of tissue regeneration in vivo (mice) and in vitro. Students will be given the opportunity to familiarize themselves with state of the art research, translational and clinical literature on the topic as well as develop their skills in critical review of literature, application of correct scientific methods, development of a research plan, drafting of experimental protocols (including animals) for funding applications, reporting and publishing research. They will be taught hands-on animal surgery techniques in mice as well as histological processing and staining methods. Our research program fosters a collaborative environment in which students have the opportunity to work with a large number of investigators and labs (muscle regeneration, vascular surgery, general surgery, dermatology, orthopedics, diabetes, transplantation surgery, cell biology) in the surrounding region. Lab meetings are held weekly where students can share the progress of their research and hear updates on projects by fellow researchers. Main ongoing investigations include among others: – Generation of a model of chronic wounds in diabetic mice – Investigation of the effect of a matrix of surfactant micelles on wound healing in diabetic mice – Development of a novel scaffold by incorporating autologous tissue in Integra and PriMatrix – Optimization of an innovative method for soft tissue reconstruction through external volume expansion


Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Christensen JM, Orgill DP. Discussion: The Interplay of Mechanical Stress, Strain, and Stiffness at the Keloid Periphery Correlates with Increased Caveolin-1/ROCK Signaling and Scar Progression. Plast Reconstr Surg. 2019 Jul; 144(1):68e-69e. PMID: 31246820.
    Citations:    
  2. Orgill DP. Response to Drs. Hua and Wei. Plast Reconstr Surg. 2019 Jul 01. PMID: 31274764.
    Citations:    
  3. Icli B, Wu W, Ozdemir D, Li H, Cheng HS, Haemmig S, Liu X, Giatsidis G, Avci SN, Lee N, Guimaraes RB, Manica A, Marchini JF, Rynning SE, Risnes I, Hollan I, Croce K, Yang X, Orgill DP, Feinberg MW. MicroRNA-615-5p Regulates Angiogenesis and Tissue Repair by Targeting AKT/eNOS (Protein Kinase B/Endothelial Nitric Oxide Synthase) Signaling in Endothelial Cells. Arterioscler Thromb Vasc Biol. 2019 Jul; 39(7):1458-1474. PMID: 31092013.
    Citations:    
  4. Sood RF, Orgill DP. Discussion: An Assessment of Bleeding Complications Necessitating Blood Transfusion across Inpatient Plastic Surgery Procedures: A Nationwide Analysis Using the National Surgical Quality Improvement Program Database. Plast Reconstr Surg. 2019 05; 143(5):1118e-1119e. PMID: 31033842.
    Citations:    
  5. Uehara M, Li X, Sheikhi A, Zandi N, Walker B, Saleh B, Banouni N, Jiang L, Ordikhani F, Dai L, Yonar M, Vohra I, Kasinath V, Orgill DP, Khademhosseini A, Annabi N, Abdi R. Anti-IL-6 eluting immunomodulatory biomaterials prolong skin allograft survival. Sci Rep. 2019 Apr 25; 9(1):6535. PMID: 31024011.
    Citations:    
  6. Taylor EM, Orgill DP. Discussion: Quality and Quantity-Cultured Murine Endothelial Progenitor Cells Increase Vascularization and Decrease Fibrosis in the Fat Graft. Plast Reconstr Surg. 2019 04; 143(4):756e-757e. PMID: 30921124.
    Citations:    
  7. Roh DS, Orgill DP. Discussion: The Preparation of the Recipient Site in Fat Grafting: A Comprehensive Review of the Preclinical Evidence. Plast Reconstr Surg. 2019 04; 143(4):1108-1110. PMID: 30921130.
    Citations:    
  8. Tappenbeck N, Schröder HM, Niebergall-Roth E, Hassinger F, Dehio U, Dieter K, Kraft K, Kerstan A, Esterlechner J, Frank NY, Scharffetter-Kochanek K, Murphy GF, Orgill DP, Beck J, Frank MH, Ganss C, Kluth MA. In vivo safety profile and biodistribution of GMP-manufactured human skin-derived ABCB5-positive mesenchymal stromal cells for use in clinical trials. Cytotherapy. 2019 May; 21(5):546-560. PMID: 30878384.
    Citations:    
  9. Alikhan A, Sayed C, Alavi A, Alhusayen R, Brassard A, Burkhart C, Crowell K, Eisen DB, Gottlieb AB, Hamzavi I, Hazen PG, Jaleel T, Kimball AB, Kirby J, Lowes MA, Micheletti R, Miller A, Naik HB, Orgill D, Poulin Y. North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part II: Topical, intralesional, and systemic medical management. J Am Acad Dermatol. 2019 Jul; 81(1):91-101. PMID: 30872149.
    Citations:    
  10. Alikhan A, Sayed C, Alavi A, Alhusayen R, Brassard A, Burkhart C, Crowell K, Eisen DB, Gottlieb AB, Hamzavi I, Hazen PG, Jaleel T, Kimball AB, Kirby J, Lowes MA, Micheletti R, Miller A, Naik HB, Orgill D, Poulin Y. North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: Diagnosis, evaluation, and the use of complementary and procedural management. J Am Acad Dermatol. 2019 Jul; 81(1):76-90. PMID: 30872156.
    Citations:    
  11. Liu Y, Xu S, Zu T, Li F, Sang S, Liu C, An Y, Mi B, Orgill DP, Murphy GF, Lian CG. Reversal of TET-mediated 5-hmC loss in hypoxic fibroblasts by ascorbic acid. Lab Invest. 2019 Mar 05. PMID: 30837678.
    Citations:    
  12. Wei S, Orgill DP, Giatsidis G. Delivery of External Volume Expansion through Microdeformational Interfaces Safely Induces Angiogenesis in a Murine Model of Intact Diabetic Skin with Endothelial Cell Dysfunction. Plast Reconstr Surg. 2019 02; 143(2):453-464. PMID: 30531623.
    Citations:    Fields:    
  13. Icli B, Wu W, Ozdemir D, Li H, Haemmig S, Liu X, Giatsidis G, Cheng HS, Avci SN, Kurt M, Lee N, Guimaraes RB, Manica A, Marchini JF, Rynning SE, Risnes I, Hollan I, Croce K, Orgill DP, Feinberg MW. MicroRNA-135a-3p regulates angiogenesis and tissue repair by targeting p38 signaling in endothelial cells. FASEB J. 2019 Apr; 33(4):5599-5614. PMID: 30668922.
    Citations:    Fields:    
  14. Roh DS, Panayi AC, Bhasin S, Orgill DP, Sinha I. Implications of Aging in Plastic Surgery. Plast Reconstr Surg Glob Open. 2019 Jan; 7(1):e2085. PMID: 30859042.
    Citations:    
  15. Contessi Negrini N, Bonnetier M, Giatsidis G, Orgill DP, Farè S, Marelli B. Tissue-mimicking gelatin scaffolds by alginate sacrificial templates for adipose tissue engineering. Acta Biomater. 2019 Mar 15; 87:61-75. PMID: 30654214.
    Citations:    Fields:    
  16. Liu Y, Panayi AC, Bayer LR, Orgill DP. Current Available Cellular and Tissue-Based Products for Treatment of Skin Defects. Adv Skin Wound Care. 2019 Jan; 32(1):19-25. PMID: 30570555.
    Citations:    Fields:    
  17. Gabriel A, Gupta S, Orgill DP. Challenges and Management of Surgical Site Occurrences. Plast Reconstr Surg. 2019 01; 143(1S Management of Surgical Incisions Utilizing Closed-Incision Negative-Pressure Therapy):7S-10S. PMID: 30586096.
    Citations:    Fields:    
  18. Arnold PB, Orgill DP. Discussion: Is Reconstruction Preserving the First Ray or First Two Rays Better Than Full Transmetatarsal Amputation in Diabetic Foot? Plast Reconstr Surg. 2019 01; 143(1):306-307. PMID: 30589806.
    Citations:    Fields:    
  19. Gabriel A, Maxwell GP, Orgill DP. Introduction to "Management of Surgical Incisions Utilizing Closed-Incision Negative-Pressure Therapy". Plast Reconstr Surg. 2019 01; 143(1S Management of Surgical Incisions Utilizing Closed-Incision Negative-Pressure Therapy):4S-5S. PMID: 30586095.
    Citations:    Fields:    
  20. Panayi AC, Orgill DP. Current Use of Biological Scaffolds in Plastic Surgery. Plast Reconstr Surg. 2019 01; 143(1):209-220. PMID: 30286046.
    Citations:    Fields:    
  21. Wei S, Liu W, Gundogan B, Moscoso AV, Orgill DP, Giatsidis G. Delayed Postconditioning with External Volume Expansion Improves Survival of Adipose Tissue Grafts in a Murine Model. Plast Reconstr Surg. 2019 01; 143(1):99e-110e. PMID: 30325898.
    Citations:    Fields:    
  22. Agha RA, Al Omran Y, Wellstead G, Sagoo H, Barai I, Rajmohan S, Borrelli MR, Vella-Baldacchino M, Orgill DP, Rusby JE. Systematic review of therapeutic nipple-sparing versus skin-sparing mastectomy. BJS Open. 2019 Apr; 3(2):135-145. PMID: 30957059.
    Citations:    
  23. Rhodius P, Haddad A, Matsumine H, Sakthivel D, Ackermann M, Sinha I, Orgill DP, Giatsidis G. Noninvasive Flap Preconditioning by Foam-Mediated External Suction Improves the Survival of Fasciocutaneous Axial-Pattern Flaps in a Type 2 Diabetic Murine Model. Plast Reconstr Surg. 2018 12; 142(6):872e-883e. PMID: 30188471.
    Citations:    Fields:    
  24. Panayi AC, Orkaby AR, Sakthivel D, Endo Y, Varon D, Roh D, Orgill DP, Neppl RL, Javedan H, Bhasin S, Sinha I. Impact of frailty on outcomes in surgical patients: A systematic review and meta-analysis. Am J Surg. 2018 Nov 27. PMID: 30509455.
    Citations:    Fields:    
  25. Agha RA, Borrelli MR, Farwana R, Koshy K, Fowler AJ, Orgill DP. The PROCESS 2018 statement: Updating Consensus Preferred Reporting Of CasE Series in Surgery (PROCESS) guidelines. Int J Surg. 2018 Dec; 60:279-282. PMID: 30359781.
    Citations:    Fields:    
  26. Agha RA, Borrelli MR, Farwana R, Koshy K, Fowler AJ, Orgill DP. The SCARE 2018 statement: Updating consensus Surgical CAse REport (SCARE) guidelines. Int J Surg. 2018 Dec; 60:132-136. PMID: 30342279.
    Citations:    Fields:    
  27. Giatsidis G, Succar J, Haddad A, Lago G, Schaffer C, Wang X, Schilling B, Chnari E, Matsumine H, Orgill DP. Preclinical Optimization of a Shelf-Ready, Injectable, Human-Derived, Decellularized Allograft Adipose Matrix. Tissue Eng Part A. 2019 02; 25(3-4):271-287. PMID: 30084731.
    Citations:    Fields:    
  28. Aycart MA, Eble DJ, Ross KM, Orgill DP. Mechanisms of Action of Instillation and Dwell Negative Pressure Wound Therapy with Case Reports of Clinical Applications. Cureus. 2018 Sep 27; 10(9):e3377. PMID: 30524912.
    Citations:    
  29. Mella JR, Ross KM, Li GZ, Pomahac B, Raut CP, Orgill DP. Cutaneous Breast Radiation-associated Angiosarcoma: Anterior Chest Wall Reconstruction Options Following Extra-radical Resection. Plast Reconstr Surg Glob Open. 2018 Sep; 6(9):e1938. PMID: 30349797.
    Citations:    
  30. DiDomenico LA, Orgill DP, Galiano RD, Serena TE, Carter MJ, Kaufman JP, Young NJ, Jacobs AM, Zelen CM. Use of an aseptically processed, dehydrated human amnion and chorion membrane improves likelihood and rate of healing in chronic diabetic foot ulcers: A prospective, randomised, multi-centre clinical trial in 80 patients. Int Wound J. 2018 Dec; 15(6):950-957. PMID: 30019528.
    Citations:    Fields:    
  31. Giatsidis G, Guyette JP, Ott HC, Orgill DP. Development of a large-volume human-derived adipose acellular allogenic flap by perfusion decellularization. Wound Repair Regen. 2018 03; 26(2):245-250. PMID: 29617055.
    Citations:    Fields:    
  32. Agha RA, Pidgeon TE, Borrelli MR, Dowlut N, Orkar TK, Ahmed M, Pujji O, Orgill DP. Validated Outcomes in the Grafting of Autologous Fat to the Breast: The VOGUE Study. Development of a Core Outcome Set for Research and Audit. Plast Reconstr Surg. 2018 05; 141(5):633e-638e. PMID: 29697603.
    Citations:    Fields:    Translation:Humans
  33. Zelen CM, Orgill DP, Serena TE, Galiano RE, Carter MJ, DiDomenico LA, Keller J, Kaufman JP, Li WW. An aseptically processed, acellular, reticular, allogenic human dermis improves healing in diabetic foot ulcers: A prospective, randomised, controlled, multicentre follow-up trial. Int Wound J. 2018 Oct; 15(5):731-739. PMID: 29682897.
    Citations:    Fields:    Translation:Humans
  34. Wang C, Luan J, Panayi AC, Orgill DP, Xin M. Complications in breast augmentation with textured versus smooth breast implants: a systematic review protocol. BMJ Open. 2018 04 10; 8(4):e020671. PMID: 29643164.
    Citations:    Fields:    
  35. Heit YI, Orgill DP. Discussion: External Volume Expansion Up-Regulates CXCL12 Expression and Enhances Mesenchymal Stromal Cell Recruitment toward Expanded Prefabricated Adipose Tissue in Rats. Plast Reconstr Surg. 2018 04; 141(4):538e-539e. PMID: 29595729.
    Citations:    Fields:    Translation:AnimalsCells
  36. Ross KM, Moscoso AV, Bayer LR, Rosselli-Risal L, Orgill DP. Plastic Surgery Complications from Medical Tourism Treated in a U.S. Academic Medical Center. Plast Reconstr Surg. 2018 04; 141(4):517e-523e. PMID: 29595725.
    Citations:    Fields:    Translation:Humans
  37. Panayi AC, Agha RA, Sieber BA, Orgill DP. Impact of Obesity on Outcomes in Breast Reconstruction: A Systematic Review and Meta-Analysis. J Reconstr Microsurg. 2018 Jun; 34(5):363-375. PMID: 29510420.
    Citations:    Fields:    Translation:Humans
  38. Thorlacius L, Garg A, Ingram JR, Villumsen B, Theut Riis P, Gottlieb AB, Merola JF, Dellavalle R, Ardon C, Baba R, Bechara FG, Cohen AD, Daham N, Davis M, Emtestam L, Fernández-Peñas P, Filippelli M, Gibbons A, Grant T, Guilbault S, Gulliver S, Harris C, Harvent C, Houston K, Kirby JS, Matusiak L, Mehdizadeh A, Mojica T, Okun M, Orgill D, Pallack L, Parks-Miller A, Prens EP, Randell S, Rogers C, Rosen CF, Choon SE, van der Zee HH, Christensen R, Jemec GBE. Towards global consensus on core outcomes for hidradenitis suppurativa research: an update from the HISTORIC consensus meetings I and II. Br J Dermatol. 2018 03; 178(3):715-721. PMID: 29080368.
    Citations: 1     Fields:    
  39. Roh DS, Orgill DP. Discussion: Early Macrophage Infiltration Improves Fat Graft Survival by Inducing Angiogenesis and Hematopoietic Stem Cell Recruitment. Plast Reconstr Surg. 2018 02; 141(2):387-388. PMID: 29369989.
    Citations:    Fields:    Translation:HumansCells
  40. Ogawa R, Daya M, Orgill DP. Discussion: Percutaneous Mesh Expansion: A Regenerative Wound Closure Alternative. Plast Reconstr Surg. 2018 02; 141(2):458-459. PMID: 29369998.
    Citations:    Fields:    Translation:Humans
  41. Sinha I, Giatsidis G, Orgill DP. Discussion: Protective Effect of Hydrogen Gas Inhalation on Muscular Damage Using a Mouse Hindlimb Ischemia-Reperfusion Injury Model. Plast Reconstr Surg. 2017 12; 140(6):1207-1208. PMID: 29176415.
    Citations:    Fields:    
  42. Giatsidis G, Cheng L, Haddad A, Ji K, Succar J, Lancerotto L, Lujan-Hernandez J, Fiorina P, Matsumine H, Orgill DP. Noninvasive induction of angiogenesis in tissues by external suction: sequential optimization for use in reconstructive surgery. Angiogenesis. 2018 Feb; 21(1):61-78. PMID: 29147813.
    Citations:    Fields:    
  43. Sîrbulescu RF, Boehm CK, Soon E, Wilks MQ, Ilies I, Yuan H, Maxner B, Chronos N, Kaittanis C, Normandin MD, El Fakhri G, Orgill DP, Sluder AE, Poznansky MC. Mature B cells accelerate wound healing after acute and chronic diabetic skin lesions. Wound Repair Regen. 2017 09; 25(5):774-791. PMID: 28922523.
    Citations: 2     Fields:    Translation:AnimalsCells
  44. Agha RA, Borrelli MR, Vella-Baldacchino M, Thavayogan R, Orgill DP. The STROCSS statement: Strengthening the Reporting of Cohort Studies in Surgery. Int J Surg. 2017 Oct; 46:198-202. PMID: 28890409.
    Citations: 37     Fields:    Translation:Humans
  45. Agha RA, Fowler AJ, Saeta A, Barai I, Rajmohan S, Orgill DP. Erratum to "Erratum to "The SCARE guidelines: Consensus-based surgical case report guidelines" [Int. J. Surg. 34 (2016) 180-186]" [Int. J. Surg. 36 (2016) 396]. Int J Surg. 2017 11; 47:151. PMID: 28847721.
    Citations: 1     Fields:    
  46. Agha RA, Borrelli MR, Farwana R, Kusu-Orkar T, Millip MC, Thavayogan R, Garner J, Darhouse N, Orgill DP. Impact of the PROCESS guideline on the reporting of surgical case series: A before and after study. Int J Surg. 2017 Sep; 45:92-97. PMID: 28760706.
    Citations: 2     Fields:    Translation:Humans
  47. Agha RA, Farwana R, Borrelli MR, Tickunas T, Kusu-Orkar T, Millip MC, Thavayogan R, Garner J, Orgill DP. Impact of the SCARE guideline on the reporting of surgical case reports: A before and after study. Int J Surg. 2017 Sep; 45:144-148. PMID: 28757396.
    Citations: 3     Fields:    Translation:Humans
  48. DiDomenico LA, Orgill DP, Galiano RD, Serena TE, Carter MJ, Kaufman JP, Young NJ, Zelen CM. A Retrospective Crossover Study of the Use of Aseptically Processed Placental Membrane in the Treatment of Chronic Diabetic Foot Ulcers. Wounds. 2017 10; 29(10):311-316. PMID: 28873060.
    Citations:    Fields:    
  49. Seth AK, Friedstat JS, Orgill DP, Pribaz JJ, Halvorson EG. Microsurgical Burn Reconstruction. Clin Plast Surg. 2017 Oct; 44(4):823-832. PMID: 28888307.
    Citations:    Fields:    Translation:Humans
  50. Szabo Eltorai A, Huang CC, Lu JT, Ogura A, Caterson SA, Orgill DP. Selective Intraoperative Vasopressor Use Is Not Associated with Increased Risk of DIEP Flap Complications. Plast Reconstr Surg. 2017 Jul; 140(1):70e-77e. PMID: 28654605.
    Citations:    Fields:    Translation:Humans
  51. Agha RA, Barai I, Rajmohan S, Lee S, Anwar MO, Fowler AJ, Orgill DP, Altman DG. Support for reporting guidelines in surgical journals needs improvement: A systematic review. Int J Surg. 2017 Sep; 45:14-17. PMID: 28673865.
    Citations: 4     Fields:    Translation:Humans
  52. Pidgeon TE, Limb C, Agha RA, Whitehurst K, Chandrakumar C, Wellstead G, Fowler AJ, Orgill DP. The use of study registration and protocols in plastic surgery research: A systematic review. Int J Surg. 2017 Aug; 44:215-222. PMID: 28625821.
    Citations:    Fields:    Translation:Humans
  53. Chin MS, Chappell AG, Giatsidis G, Perry DJ, Lujan-Hernandez J, Haddad A, Matsumine H, Orgill DP, Lalikos JF. Hyperspectral Imaging Provides Early Prediction of Random Axial Flap Necrosis in a Preclinical Model. Plast Reconstr Surg. 2017 Jun; 139(6):1285e-1290e. PMID: 28538567.
    Citations:    Fields:    Translation:Animals
  54. Giatsidis G, Cheng L, Facchin F, Haddad A, Lujan-Hernandez J, Lancerotto L, Nabzdyk CG, Matsumine H, Orgill DP. Moderate-Intensity Intermittent External Volume Expansion Optimizes the Soft-Tissue Response in a Murine Model. Plast Reconstr Surg. 2017 Apr; 139(4):882-890. PMID: 28350665.
    Citations: 2     Fields:    Translation:Animals
  55. Haddad AG, Giatsidis G, Orgill DP, Halvorson EG. Skin Substitutes and Bioscaffolds: Temporary and Permanent Coverage. Clin Plast Surg. 2017 Jul; 44(3):627-634. PMID: 28576252.
    Citations:    Fields:    Translation:Humans
  56. Li GZ, Fairweather M, Wang J, Orgill DP, Bertagnolli MM, Raut CP. Cutaneous Radiation-associated Breast Angiosarcoma: Radicality of Surgery Impacts Survival. Ann Surg. 2017 04; 265(4):814-820. PMID: 28267696.
    Citations: 2     Fields:    Translation:Humans
  57. Matsumine H, Numakura K, Tsunoda S, Wang H, Matsumine R, Climov M, Giatsidis G, Sukhatme VP, Orgill DP. Adipose-derived aldehyde dehydrogenase-expressing cells promote dermal regenerative potential with collagen-glycosaminoglycan scaffold. Wound Repair Regen. 2017 01; 25(1):109-119. PMID: 28230922.
    Citations: 1     Fields:    Translation:AnimalsCells
  58. Zelen CM, Orgill DP, Serena TE, Galiano RD, Carter MJ, DiDomenico LA, Kaufman JP, Keller J, Young NJ, Li WW. Human Reticular Acellular Dermal Matrix in the Healing of Chronic Diabetic Foot Ulcerations that Failed Standard Conservative Treatment: A Retrospective Crossover Study. Wounds. 2017 Feb; 29(2):39-45. PMID: 28272011.
    Citations: 1     Fields:    Translation:Humans
  59. Cheng L, Ji K, Shih TY, Haddad A, Giatsidis G, Mooney DJ, Orgill DP, Nabzdyk CS. Injectable Shape-Memorizing Three-Dimensional Hyaluronic Acid Cryogels for Skin Sculpting and Soft Tissue Reconstruction. Tissue Eng Part A. 2017 03; 23(5-6):243-251. PMID: 27875939.
    Citations: 1     Fields:    Translation:Animals
  60. Ricci JA, Bayer LR, Orgill DP. Evidence-Based Medicine: The Evaluation and Treatment of Pressure Injuries. Plast Reconstr Surg. 2017 Jan; 139(1):275e-286e. PMID: 28027261.
    Citations: 2     Fields:    Translation:Humans
  61. Agha RA, Fowler AJ, Saeta A, Barai I, Rajmohan S, Orgill DP. Erratum to "The SCARE guidelines: Consensus-based surgical case report guidelines" [Int. J. Surg. 34 (2016) 180-186]. Int J Surg. 2016 12; 36(Pt A):396. PMID: 27851898.
    Citations: 8     Fields:    
  62. Agha RA, Fowler AJ, Pidgeon TE, Wellstead G, Orgill DP. The Need for Core Outcome Reporting in Autologous Fat Grafting for Breast Reconstruction. Ann Plast Surg. 2016 Nov; 77(5):506-512. PMID: 26545226.
    Citations: 3     Fields:    Translation:Humans
  63. Agha RA, Fowler AJ, Rajmohan S, Barai I, Orgill DP. Preferred reporting of case series in surgery; the PROCESS guidelines. Int J Surg. 2016 Dec; 36(Pt A):319-323. PMID: 27770639.
    Citations: 126     Fields:    Translation:Humans
  64. DiDomenico LA, Orgill DP, Galiano RD, Serena TE, Carter MJ, Kaufman JP, Young NJ, Zelen CM. Aseptically Processed Placental Membrane Improves Healing of Diabetic Foot Ulcerations: Prospective, Randomized Clinical Trial. Plast Reconstr Surg Glob Open. 2016 Oct; 4(10):e1095. PMID: 27826487.
    Citations: 3     
  65. Dasgupta A, Orgill D, Galiano RD, Zelen CM, Huang YC, Chnari E, Li WW. A Novel Reticular Dermal Graft Leverages Architectural and Biological Properties to Support Wound Repair. Plast Reconstr Surg Glob Open. 2016 Oct; 4(10):e1065. PMID: 27826469.
    Citations:    
  66. Lujan-Hernandez J, Lancerotto L, Nabzdyk C, Hassan KZ, Giatsidis G, Khouri RK, Chin MS, Bassetto F, Lalikos JF, Orgill DP. Reply: Induction of Adipogenesis by External Volume Expansion. Plast Reconstr Surg. 2016 10; 138(4):770e-2e. PMID: 27307329.
    Citations:    Fields:    Translation:HumansCells
  67. Najjar PA, Madenci AL, Zogg CK, Schneider EB, Dankers CA, Pimentel MT, Chabria AS, Goldberg JE, Sharma G, Piazza G, Bleday R, Orgill DP, Kachalia A. Implementation of a Comprehensive Post-Discharge Venous Thromboembolism Prophylaxis Program for Abdominal and Pelvic Surgery Patients. J Am Coll Surg. 2016 12; 223(6):804-813. PMID: 27693288.
    Citations:    Fields:    Translation:Humans
  68. Agha R, Fowler AJ, Limb C, Al Omran Y, Sagoo H, Koshy K, Jafree DJ, Anwar MO, McCullogh P, Orgill DP. The First 500 Registrations to the Research Registry®: Advancing Registration of Under-Registered Study Types. Front Surg. 2016; 3:50. PMID: 27695693.
    Citations: 1     
  69. Agha RA, Fowler AJ, Saeta A, Barai I, Rajmohan S, Orgill DP. The SCARE Statement: Consensus-based surgical case report guidelines. Int J Surg. 2016 Oct; 34:180-186. PMID: 27613565.
    Citations: 1048     Fields:    Translation:Humans
  70. Climov M, Bayer LR, Moscoso AV, Matsumine H, Orgill DP. The Role of Dermal Matrices in Treating Inflammatory and Diabetic Wounds. Plast Reconstr Surg. 2016 Sep; 138(3 Suppl):148S-57S. PMID: 27556755.
    Citations: 1     Fields:    Translation:Humans
  71. Agha RA, Fowler AJ, Lee SY, Gundogan B, Whitehurst K, Sagoo HK, Jeong KJ, Altman DG, Orgill DP. Systematic review of the methodological and reporting quality of case series in surgery. Br J Surg. 2016 Sep; 103(10):1253-8. PMID: 27511619.
    Citations: 1     Fields:    Translation:Humans
  72. Caterson SA, Singh M, Orgill D, Ghazinouri R, Han E, Ciociolo G, Laskowski K, Greenberg JO. Erratum: Development of Standardized Clinical Assessment and Management Plans (SCAMPs) in the Field of Plastic & Reconstructive Surgery: A Quality Improvement Project: Erratum. Plast Reconstr Surg Glob Open. 2016 Jul; 4(7):e510. PMID: 27536468.
    Citations:    
  73. Lazar HL, Salm TV, Engelman R, Orgill D, Gordon S. Prevention and management of sternal wound infections. J Thorac Cardiovasc Surg. 2016 10; 152(4):962-72. PMID: 27555340.
    Citations: 5     Fields:    Translation:Humans
  74. Agha RA, Orgill DP. Commentary on: Autologous Fat Grafting in Cosmetic Breast Augmentation: A Systematic Review on Radiological Safety, Complications, Volume Retention, and Patient/Surgeon Satisfaction. Aesthet Surg J. 2016 10; 36(9):1008-9. PMID: 27461486.
    Citations:    Fields:    Translation:Humans
  75. Huang C, Du Y, Nabzdyk CS, Ogawa R, Koyama T, Orgill DP, Fu X. Regeneration of hair and other skin appendages: A microenvironment-centric view. Wound Repair Regen. 2016 Sep; 24(5):759-766. PMID: 27256925.
    Citations: 2     Fields:    
  76. Orgill DP, Hergrueter CA. Discussion: Strategies for Postoperative Seroma Prevention: A Systematic Review. Plast Reconstr Surg. 2016 07; 138(1):253-4. PMID: 27348658.
    Citations:    Fields:    Translation:Humans
  77. Matsumine H, Numakura K, Climov M, Watanabe Y, Giatsidis G, Orgill DP. Facial-nerve regeneration ability of a hybrid artificial nerve conduit containing uncultured adipose-derived stromal vascular fraction: An experimental study. Microsurgery. 2017 Oct; 37(7):808-818. PMID: 27273726.
    Citations:    Fields:    Translation:AnimalsCells
  78. Agha RA, Fowler AJ, Pidgeon TE, Wellstead G, Orgill DP. Protocol for the development of a core outcome set for autologous fat grafting to the breast. Int J Surg. 2016 Jul; 31:104-6. PMID: 27262878.
    Citations: 2     Fields:    Translation:Humans
  79. Katagiri S, Park K, Maeda Y, Rao TN, Khamaisi M, Li Q, Yokomizo H, Mima A, Lancerotto L, Wagers A, Orgill DP, King GL. Overexpressing IRS1 in Endothelial Cells Enhances Angioblast Differentiation and Wound Healing in Diabetes and Insulin Resistance. Diabetes. 2016 09; 65(9):2760-71. PMID: 27217486.
    Citations: 3     Fields:    Translation:AnimalsCells
  80. Agha RA, Wellstead G, Sagoo H, Al Omran Y, Barai I, Rajmohan S, Fowler AJ, Orgill DP, Rusby JE. Nipple sparing versus skin sparing mastectomy: a systematic review protocol. BMJ Open. 2016 05 20; 6(5):e010151. PMID: 27207622.
    Citations:    Fields:    Translation:Humans
  81. Agha RA, Lee SY, Jeong KJ, Fowler AJ, Orgill DP. Reporting Quality of Observational Studies in Plastic Surgery Needs Improvement: A Systematic Review. Ann Plast Surg. 2016 May; 76(5):585-9. PMID: 25643190.
    Citations: 7     Fields:    
  82. Zelen CM, Orgill DP, Serena T, Galiano R, Carter MJ, DiDomenico LA, Keller J, Kaufman J, Li WW. A prospective, randomised, controlled, multicentre clinical trial examining healing rates, safety and cost to closure of an acellular reticular allogenic human dermis versus standard of care in the treatment of chronic diabetic foot ulcers. Int Wound J. 2017 Apr; 14(2):307-315. PMID: 27073000.
    Citations: 4     Fields:    Translation:Humans
  83. Maruthappu M, Duclos A, Zhou CD, Lipsitz SR, Wright J, Orgill D, Carty MJ. The impact of team familiarity and surgical experience on operative efficiency: a retrospective analysis. J R Soc Med. 2016 Apr; 109(4):147-53. PMID: 27053357.
    Citations: 2     Fields:    Translation:Humans
  84. Lee SY, Sagoo H, Whitehurst K, Wellstead G, Fowler AJ, Agha RA, Orgill D. Compliance of Systematic Reviews in Plastic Surgery With the PRISMA Statement. JAMA Facial Plast Surg. 2016 Mar-Apr; 18(2):101-5. PMID: 26719993.
    Citations: 2     Fields:    
  85. Wakeam E, Hyder JA, Lipsitz SR, Cohen ME, Orgill DP, Zinner MJ, Ko CY, Hall BL, Finlayson SR. Hospital-level Variation in Secondary Complications After Surgery. Ann Surg. 2016 Mar; 263(3):493-501. PMID: 25876007.
    Citations: 2     Fields:    Translation:Humans
  86. Sinha I, Orgill DP. Discussion: Opposite Effects of Soluble Factors Secreted by Adipose Tissue on Proliferating and Quiescent Osteosarcoma Cells. Plast Reconstr Surg. 2016 Mar; 137(3):876-7. PMID: 26910667.
    Citations:    Fields:    Translation:HumansAnimals
  87. Agha RA, Orgill DP. Discussion: A Systematic Review of Surgical Randomized Controlled Trials: Part I. Risk of Bias and Outcomes: Common Pitfalls Plastic Surgeons Can Overcome. Plast Reconstr Surg. 2016 Feb; 137(2):707. PMID: 26818310.
    Citations:    Fields:    
  88. Agha RA, Fowler AJ, Saetta A, Barai I, Rajmohan S, Orgill DP. A protocol for the development of reporting criteria for surgical case reports: The SCARE statement. Int J Surg. 2016 Mar; 27:187-9. PMID: 26828281.
    Citations: 51     Fields:    Translation:Humans
  89. Khamaisi M, Katagiri S, Keenan H, Park K, Maeda Y, Li Q, Qi W, Thomou T, Eschuk D, Tellechea A, Veves A, Huang C, Orgill DP, Wagers A, King GL. PKCd inhibition normalizes the wound-healing capacity of diabetic human fibroblasts. J Clin Invest. 2016 Mar 01; 126(3):837-53. PMID: 26808499.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  90. Icli B, Nabzdyk CS, Lujan-Hernandez J, Cahill M, Auster ME, Wara AK, Sun X, Ozdemir D, Giatsidis G, Orgill DP, Feinberg MW. Regulation of impaired angiogenesis in diabetic dermal wound healing by microRNA-26a. J Mol Cell Cardiol. 2016 Feb; 91:151-9. PMID: 26776318.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  91. Agha RA, Orgill DP. Evidence-Based Plastic Surgery: Its Rise, Importance, and a Practical Guide. Aesthet Surg J. 2016 Mar; 36(3):366-71. PMID: 26746230.
    Citations:    Fields:    Translation:Humans
  92. Lujan-Hernandez J, Lancerotto L, Nabzdyk C, Hassan KZ, Giatsidis G, Khouri RK, Chin MS, Bassetto F, Lalikos JF, Orgill DP. Induction of Adipogenesis by External Volume Expansion. Plast Reconstr Surg. 2016 Jan; 137(1):122-31. PMID: 26710016.
    Citations: 5     Fields:    Translation:AnimalsCells
  93. Orgill DP, Smink DS. Discussion: Large Contaminated Ventral Hernia Repair Using Component Separation Technique with Synthetic Mesh. Plast Reconstr Surg. 2015 Dec; 136(6):806e-7e. PMID: 26595035.
    Citations:    Fields:    Translation:Humans
  94. Nyame TT, Chiang HA, Leavitt T, Ozambela M, Orgill DP. Tissue-Engineered Skin Substitutes. Plast Reconstr Surg. 2015 Dec; 136(6):1379-88. PMID: 26595026.
    Citations: 5     Fields:    Translation:Humans
  95. Chin MS, Freniere BB, Lancerotto L, Lujan-Hernandez J, Saleeby JH, Lo YC, Orgill DP, Lalikos JF, Fitzgerald TJ. Hyperspectral Imaging as an Early Biomarker for Radiation Exposure and Microcirculatory Damage. Front Oncol. 2015; 5:232. PMID: 26579490.
    Citations: 2     
  96. Agha R, Fowler AJ, Lee SY, Gundogan B, Whitehurst K, Sagoo H, Jeong KJ, Altman DG, Orgill DP. A systematic review protocol for reporting deficiencies within surgical case series. BMJ Open. 2015 Oct 05; 5(10):e008007. PMID: 26438134.
    Citations:    Fields:    Translation:Humans
  97. Janis JE, Khansa I, Lehrman CR, Orgill DP, Pomahac B. Reconstructive Management of Devastating Electrical Injuries to the Face. Plast Reconstr Surg. 2015 Oct; 136(4):839-47. PMID: 26090762.
    Citations: 2     Fields:    Translation:Humans
  98. Agha R, Fowler A, Orgill DP. Tissue-Engineered Breast Reconstruction with Brava-Assisted Fat Grafting: A 7-Year, 488-Patient, Multicenter Experience. Plast Reconstr Surg. 2015 Oct; 136(4):556e-7e. PMID: 26110212.
    Citations:    Fields:    Translation:Humans
  99. Caterson SA, Singh M, Orgill D, Ghazinouri R, Han E, Ciociolo G, Laskowski K, Greenberg JO. Development of Standardized Clinical Assessment and Management Plans (SCAMPs) in Plastic and Reconstructive Surgery. Plast Reconstr Surg Glob Open. 2015 Sep; 3(9):e510. PMID: 26495223.
    Citations: 2     
  100. Offodile AC, Pathak A, Wenger J, Orgill DP, Guo L. Prevalence and Patient-Level Risk Factors for 30-Day Readmissions Following Free Tissue Transfer for Head and Neck Cancer. JAMA Otolaryngol Head Neck Surg. 2015 Sep; 141(9):783-9. PMID: 26204558.
    Citations: 3     Fields:    Translation:Humans
  101. Min H, Morales DR, Orgill D, Smink DS, Yule S. Systematic review of coaching to enhance surgeons' operative performance. Surgery. 2015 Nov; 158(5):1168-91. PMID: 25956742.
    Citations: 4     Fields:    Translation:Humans
  102. Maruthappu M, Duclos A, Lipsitz SR, Orgill D, Carty MJ. Surgical learning curves and operative efficiency: a cross-specialty observational study. BMJ Open. 2015 Mar 13; 5(3):e006679. PMID: 25770229.
    Citations: 5     Fields:    Translation:Humans
  103. Offodile AC, Aherrera AS, Wenger J, Tsai T, Orgill DP, Guo L. Impact of Specialty Training on the Association between Flap Size and Incidence of Complications following Microvascular Head and Neck Reconstruction for Cancer. J Reconstr Microsurg. 2015 Jun; 31(5):348-54. PMID: 25769086.
    Citations:    Fields:    Translation:Humans
  104. Gobble RM, Orgill DP. Reply: Ketorolac does not increase postoperative bleeding: a meta-analysis of randomized controlled trials. Plast Reconstr Surg. 2015 Mar; 135(3):649e. PMID: 25635330.
    Citations:    Fields:    Translation:Humans
  105. Gibbons GW, Orgill DP, Serena TE, Novoung A, O'Connell JB, Li WW, Driver VR. A prospective, randomized, controlled trial comparing the effects of noncontact, low-frequency ultrasound to standard care in healing venous leg ulcers. Ostomy Wound Manage. 2015 Jan; 61(1):16-29. PMID: 25581604.
    Citations: 2     Fields:    Translation:Humans
  106. Halvorson EG, Orgill DP. Discussion: reverse lymphatic mapping: a new technique for maximizing safety in vascularized lymph node transfer. Plast Reconstr Surg. 2015 Jan; 135(1):286-8. PMID: 25539312.
    Citations:    Fields:    Translation:Humans
  107. Fairweather M, Heit YI, Buie J, Rosenberg LM, Briggs A, Orgill DP, Bertagnolli MM. Celecoxib inhibits early cutaneous wo