Harvard Catalyst Profiles

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Edward S. Horton, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01ES024765 (OKEN, EMILY) Mar 1, 2015 - Feb 28, 2020
    NIH/NIEHS
    Longitudinal Association of PFCs with Obesity, Diabetes, and Metabolic Syndrome
    Role: Principal Investigator
  2. U01DK048437 (HORTON, EDWARD SCHURR) Aug 20, 1994 - Jan 31, 2021
    NIH/NIDDK
    07/22 Diabetes Prevention Program Outcomes Study (DPPOS)Phase 3 - Research Project
    Role: Principal Investigator
  3. P30DK036836 (KING, GEORGE L) Sep 30, 1986 - Mar 31, 2022
    NIH/NIDDK
    Diabetes Research Center
    Role: Co-Principal Investigator
  4. T32DK007523 (HORTON, EDWARD S) Jan 1, 1986 - Dec 31, 1991
    NIH/NIDDK
    TRAINING IN DIABETES, ENDOCRINOLOGY AND METABOLISM
    Role: Principal Investigator
  5. M01RR002635 (GOTTLIEB, GARY L) Dec 1, 1984 - Mar 31, 2010
    NIH/NCRR
    General Clinical Research Center
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Houston DK, Neiberg RH, Miller ME, Hill JO, Jakicic JM, Johnson KC, Gregg EW, Hubbard VS, Pi-Sunyer X, Rejeski WJ, Wing RR, Bantle JP, Beale E, Berkowitz RI, Cassidy-Begay M, Clark JM, Coday M, Delahanty LM, Dutton G, Egan C, Foreyt JP, Greenway FL, Hazuda HP, Hergenroeder A, Horton ES, Jeffery RW, Kahn SE, Kure A, Knowler WC, Lewis CE, Martin CK, Michaels S, Montez MG, Nathan DM, Patricio J, Peters A, Pownall H, Regensteiner J, Steinburg H, Wadden TA, White K, Yanovski SZ, Zhang P, Kritchevsky SB. Physical Function Following a Long-Term Lifestyle Intervention Among Middle Aged and Older Adults With Type 2 Diabetes: The Look AHEAD Study. J Gerontol A Biol Sci Med Sci. 2018 Oct 08; 73(11):1552-1559. PMID: 29053861.
    Citations: 1     Fields:    
  2. Cardenas A, Hauser R, Gold DR, Kleinman KP, Hivert MF, Fleisch AF, Lin PD, Calafat AM, Webster TF, Horton ES, Oken E. Association of Perfluoroalkyl and Polyfluoroalkyl Substances With Adiposity. JAMA Netw Open. 2018 Aug 03; 1(4):e181493. PMID: 30646133.
    Citations:    
  3. Connelly K, Gandhi S, Horton E. Lifestyle and CV Risk in Patients With Diabetes: Time to Get "Back to Basics". J Am Coll Cardiol. 2018 Jun 26; 71(25):2877-2879. PMID: 29929609.
    Citations:    Fields:    
  4. Brinkley TE, Anderson A, Soliman EZ, Bertoni AG, Greenway F, Knowler WC, Glasser SP, Horton ES, Espeland MA. Long-Term Effects of an Intensive Lifestyle Intervention on Electrocardiographic Criteria for Left Ventricular Hypertrophy: The Look AHEAD Trial. Am J Hypertens. 2018 Apr 13; 31(5):541-548. PMID: 29324968.
    Citations:    Fields:    
  5. Espeland MA, Carmichael O, Hayden K, Neiberg RH, Newman AB, Keller JN, Wadden TA, Rapp SR, Hill JO, Horton ES, Johnson KC, Wagenknecht L, Wing RR. Long-term Impact of Weight Loss Intervention on Changes in Cognitive Function: Exploratory Analyses from the Action for Health in Diabetes Randomized Controlled Clinical Trial. J Gerontol A Biol Sci Med Sci. 2018 Mar 14; 73(4):484-491. PMID: 28958022.
    Citations: 1     Fields:    
  6. Herman WH, Pan Q, Edelstein SL, Mather KJ, Perreault L, Barrett-Connor E, Dabelea DM, Horton E, Kahn SE, Knowler WC, Lorenzo C, Pi-Sunyer X, Venditti E, Ye W. Erratum. Impact of Lifestyle and Metformin Interventions on the Risk of Progression to Diabetes and Regression to Normal Glucose Regulation in Overweight or Obese People With Impaired Glucose Regulation. Diabetes Care 2017;40:1668-1677. Diabetes Care. 2018 04; 41(4):913. PMID: 29475844.
    Citations:    Fields:    
  7. Espeland MA, Luchsinger JA, Neiberg RH, Carmichael O, Laurienti PJ, Pi-Sunyer X, Wing RR, Cook D, Horton E, Casanova R, Erickson K, Nick Bryan R. Long Term Effect of Intensive Lifestyle Intervention on Cerebral Blood Flow. J Am Geriatr Soc. 2018 Jan; 66(1):120-126. PMID: 29082505.
    Citations: 2     Fields:    
  8. Herman WH, Pan Q, Edelstein SL, Mather KJ, Perreault L, Barrett-Connor E, Dabelea DM, Horton E, Kahn SE, Knowler WC, Lorenzo C, Pi-Sunyer X, Venditti E, Ye W. Impact of Lifestyle and Metformin Interventions on the Risk of Progression to Diabetes and Regression to Normal Glucose Regulation in Overweight or Obese People With Impaired Glucose Regulation. Diabetes Care. 2017 12; 40(12):1668-1677. PMID: 29021207.
    Citations: 1     Fields:    Translation:Humans
  9. Hayden KM, Baker LD, Bray G, Carvajal R, Demos-McDermott K, Hergenroeder AL, Hill JO, Horton E, Jakicic JM, Johnson KC, Neiberg RH, Rapp SR, Wadden TA, Miller ME. Long-term impact of intensive lifestyle intervention on cognitive function assessed with the National Institutes of Health Toolbox: The Look AHEAD study. Alzheimers Dement (Amst). 2018; 10:41-48. PMID: 29159267.
    Citations:    
  10. Cardenas A, Gold DR, Hauser R, Kleinman KP, Hivert MF, Calafat AM, Ye X, Webster TF, Horton ES, Oken E. Plasma Concentrations of Per- and Polyfluoroalkyl Substances at Baseline and Associations with Glycemic Indicators and Diabetes Incidence among High-Risk Adults in the Diabetes Prevention Program Trial. Environ Health Perspect. 2017 10 02; 125(10):107001. PMID: 28974480.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  11. Sylvetsky AC, Edelstein SL, Walford G, Boyko EJ, Horton ES, Ibebuogu UN, Knowler WC, Montez MG, Temprosa M, Hoskin M, Rother KI, Delahanty LM. A High-Carbohydrate, High-Fiber, Low-Fat Diet Results in Weight Loss among Adults at High Risk of Type 2 Diabetes. J Nutr. 2017 11; 147(11):2060-2066. PMID: 28954840.
    Citations: 2     Fields:    Translation:Humans
  12. Johnson KC, Bray GA, Cheskin LJ, Clark JM, Egan CM, Foreyt JP, Garcia KR, Glasser S, Greenway FL, Gregg EW, Hazuda HP, Hergenroeder A, Hill JO, Horton ES, Jakicic JM, Jeffery RW, Kahn SE, Knowler WC, Lewis CE, Miller M, Montez MG, Nathan DM, Patricio JL, Peters AL, Pi-Sunyer X, Pownall HJ, Reboussin D, Redmon JB, Steinberg H, Wadden TA, Wagenknecht LE, Wing RR, Womack CR, Yanovski SZ, Zhang P, Schwartz AV. The Effect of Intentional Weight Loss on Fracture Risk in Persons With Diabetes: Results From the Look AHEAD Randomized Clinical Trial. J Bone Miner Res. 2017 Nov; 32(11):2278-2287. PMID: 28678345.
    Citations: 3     Fields:    Translation:Humans
  13. Goldberg RB, Aroda VR, Bluemke DA, Barrett-Connor E, Budoff M, Crandall JP, Dabelea D, Horton ES, Mather KJ, Orchard TJ, Schade D, Watson K, Temprosa M. Effect of Long-Term Metformin and Lifestyle in the Diabetes Prevention Program and Its Outcome Study on Coronary Artery Calcium. Circulation. 2017 Jul 04; 136(1):52-64. PMID: 28476766.
    Citations: 4     Fields:    Translation:Humans
  14. Espeland MA, Luchsinger JA, Baker LD, Neiberg R, Kahn SE, Arnold SE, Wing RR, Blackburn GL, Bray G, Evans M, Hazuda HP, Jeffery RW, Wilson VM, Clark JM, Coday M, Demos-McDermott K, Foreyt JP, Greenway F, Hill JO, Horton ES, Jakicic JM, Johnson KC, Knowler WC, Lewis CE, Nathan DM, Peters A, Pi-Sunyer X, Pownall H, Wadden TA, Rapp SR. Effect of a long-term intensive lifestyle intervention on prevalence of cognitive impairment. Neurology. 2017 May 23; 88(21):2026-2035. PMID: 28446656.
    Citations: 5     Fields:    Translation:Humans
  15. McCaffery JM, Jablonski KA, Franks PW, Delahanty LM, Aroda V, Marrero D, Hamman RF, Horton ES, Dagogo-Jack S, Wylie-Rosett J, Barrett-Connor E, Kitabchi A, Knowler WC, Wing RR, Florez JC. Replication of the Association of BDNF and MC4R Variants With Dietary Intake in the Diabetes Prevention Program. Psychosom Med. 2017 Feb/Mar; 79(2):224-233. PMID: 27551991.
    Citations: 3     Fields:    Translation:Humans
  16. Goldberg RB, Temprosa M, Mele L, Orchard T, Mather K, Bray G, Horton E, Kitabchi A, Krakoff J, Marcovina S, Perreault L, White N. Erratum to: "Change in adiponectin explains most of the change in HDL particles induced by lifestyle intervention but not metformin treatment in the diabetes prevention program" [Metabolism (2016) 65; 764-775]. Metabolism. 2017 03; 68:184-186. PMID: 28065437.
    Citations:    Fields:    
  17. Fried PJ, Schilberg L, Brem AK, Saxena S, Wong B, Cypess AM, Horton ES, Pascual-Leone A. Humans with Type-2 Diabetes Show Abnormal Long-Term Potentiation-Like Cortical Plasticity Associated with Verbal Learning Deficits. J Alzheimers Dis. 2017; 55(1):89-100. PMID: 27636847.
    Citations: 7     Fields:    Translation:Humans
  18. Colberg SR, Sigal RJ, Yardley JE, Riddell MC, Dunstan DW, Dempsey PC, Horton ES, Castorino K, Tate DF. Physical Activity/Exercise and Diabetes: A Position Statement of the American Diabetes Association. Diabetes Care. 2016 11; 39(11):2065-2079. PMID: 27926890.
    Citations: 61     Fields:    
  19. Varga TV, Winters AH, Jablonski KA, Horton ES, Khare-Ranade P, Knowler WC, Marcovina SM, Renström F, Watson KE, Goldberg R, Florez JC, Pollin TI, Franks PW. Comprehensive Analysis of Established Dyslipidemia-Associated Loci in the Diabetes Prevention Program. Circ Cardiovasc Genet. 2016 Dec; 9(6):495-503. PMID: 27784733.
    Citations: 2     Fields:    Translation:Humans
  20. Doupis J, Papanas N, Cohen A, McFarlan L, Horton E. Pulse Wave Analysis by Applanation Tonometry for the Measurement of Arterial Stiffness. Open Cardiovasc Med J. 2016; 10:188-95. PMID: 27651842.
    Citations: 2     
  21. Gregg EW, Jakicic JM, Blackburn G, Bloomquist P, Bray GA, Clark JM, Coday M, Curtis JM, Egan C, Evans M, Foreyt J, Foster G, Hazuda HP, Hill JO, Horton ES, Hubbard VS, Jeffery RW, Johnson KC, Kitabchi AE, Knowler WC, Kriska A, Lang W, Lewis CE, Montez MG, Nathan DM, Neiberg RH, Patricio J, Peters A, Pi-Sunyer X, Pownall H, Redmon B, Regensteiner J, Rejeski J, Ribisl PM, Safford M, Stewart K, Trence D, Wadden TA, Wing RR, Yanovski SZ. Association of the magnitude of weight loss and changes in physical fitness with long-term cardiovascular disease outcomes in overweight or obese people with type 2 diabetes: a post-hoc analysis of the Look AHEAD randomised clinical trial. Lancet Diabetes Endocrinol. 2016 11; 4(11):913-921. PMID: 27595918.
    Citations: 22     Fields:    Translation:Humans
  22. Kim C, Barrett-Connor E, Aroda VR, Mather KJ, Christophi CA, Horton ES, Pi-Sunyer X, Bray GA, Labrie F, Golden SH. Testosterone and depressive symptoms among men in the Diabetes Prevention Program. Psychoneuroendocrinology. 2016 10; 72:63-71. PMID: 27371769.
    Citations: 3     Fields:    Translation:Humans
  23. Goldberg RB, Temprosa M, Mele L, Orchard T, Mather K, Bray G, Horton E, Kitabchi A, Krakoff J, Marcovina S, Perreault L, White N. Change in adiponectin explains most of the change in HDL particles induced by lifestyle intervention but not metformin treatment in the Diabetes Prevention Program. Metabolism. 2016 May; 65(5):764-75. PMID: 27085783.
    Citations: 4     Fields:    Translation:Humans
  24. Hivert MF, Christophi CA, Franks PW, Jablonski KA, Ehrmann DA, Kahn SE, Horton ES, Pollin TI, Mather KJ, Perreault L, Barrett-Connor E, Knowler WC, Florez JC. Lifestyle and Metformin Ameliorate Insulin Sensitivity Independently of the Genetic Burden of Established Insulin Resistance Variants in Diabetes Prevention Program Participants. Diabetes. 2016 Feb; 65(2):520-6. PMID: 26525880; PMCID: PMC4747453.
    Citations: 5     Fields:    Translation:Humans
  25. Munshi MN, Segal AR, Slyne C, Samur AA, Brooks KM, Horton ES. Shortfalls of the use of HbA1C-derived eAG in older adults with diabetes. Diabetes Res Clin Pract. 2015 Oct; 110(1):60-65. PMID: 26272739.
    Citations: 4     Fields:    Translation:Humans
  26. Handelsman Y, Bloomgarden ZT, Grunberger G, Umpierrez G, Zimmerman RS, Bailey TS, Blonde L, Bray GA, Cohen AJ, Dagogo-Jack S, Davidson JA, Einhorn D, Ganda OP, Garber AJ, Garvey WT, Henry RR, Hirsch IB, Horton ES, Hurley DL, Jellinger PS, Jovanovic L, Lebovitz HE, LeRoith D, Levy P, McGill JB, Mechanick JI, Mestman JH, Moghissi ES, Orzeck EA, Pessah-Pollack R, Rosenblit PD, Vinik AI, Wyne K, Zangeneh F. AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY - CLINICAL PRACTICE GUIDELINES FOR DEVELOPING A DIABETES MELLITUS COMPREHENSIVE CARE PLAN - 2015. Endocr Pract. 2015 Apr; 21 Suppl 1:1-87. PMID: 26131596.
    Citations:    
  27. Handelsman Y, Bloomgarden ZT, Grunberger G, Umpierrez G, Zimmerman RS, Bailey TS, Blonde L, Bray GA, Cohen AJ, Dagogo-Jack S, Davidson JA, Einhorn D, Ganda OP, Garber AJ, Garvey WT, Henry RR, Hirsch IB, Horton ES, Hurley DL, Jellinger PS, Jovanovic L, Lebovitz HE, LeRoith D, Levy P, McGill JB, Mechanick JI, Mestman JH, Moghissi ES, Orzeck EA, Pessah-Pollack R, Rosenblit PD, Vinik AI, Wyne K, Zangeneh F. AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY--CLINICAL PRACTICE GUIDELINES FOR DEVELOPING A DIABETES MELLITUS COMPREHENSIVE CARE PLAN--2015--EXECUTIVE SUMMARY. Endocr Pract. 2015 Apr; 21(4):413-37. PMID: 27408942.
    Citations: 11     Fields:    Translation:Humans
  28. Marrero DG, Ma Y, de Groot M, Horton ES, Price DW, Barrett-Connor E, Carnethon MR, Knowler WC. Depressive symptoms, antidepressant medication use, and new onset of diabetes in participants of the diabetes prevention program and the diabetes prevention program outcomes study. Psychosom Med. 2015 Apr; 77(3):303-10. PMID: 25775165; PMCID: PMC4397126.
    Citations:    Fields:    Translation:Humans
  29. Handelsman Y, Bloomgarden ZT, Grunberger G, Umpierrez G, Zimmerman RS, Bailey TS, Blonde L, Bray GA, Cohen AJ, Dagogo-Jack S, Davidson JA, Einhorn D, Ganda OP, Garber AJ, Garvey WT, Henry RR, Hirsch IB, Horton ES, Hurley DL, Jellinger PS, Jovanovic L, Lebovitz HE, LeRoith D, Levy P, McGill JB, Mechanick JI, Mestman JH, Moghissi ES, Orzeck EA, Pessah-Pollack R, Rosenblit PD, Vinik AI, Wyne K, Zangeneh F. American association of clinical endocrinologists and american college of endocrinology - clinical practice guidelines for developing a diabetes mellitus comprehensive care plan - 2015. Endocr Pract. 2015 Apr; 21 Suppl 1:1-87. PMID: 25869408.
    Citations: 81     Fields:    
  30. Peng C, Luttmann-Gibson H, Zanobetti A, Cohen A, De Souza C, Coull BA, Horton ES, Schwartz J, Koutrakis P, Gold DR. AIR POLLUTION INFLUENCES ON EXHALED NITRIC OXIDE AMONG PEOPLE WITH TYPE II DIABETES. Air Qual Atmos Health. 2016 Apr; 9(3):265-273. PMID: 27213020.
    Citations: 1     
  31. Hamman RF, Horton E, Barrett-Connor E, Bray GA, Christophi CA, Crandall J, Florez JC, Fowler S, Goldberg R, Kahn SE, Knowler WC, Lachin JM, Murphy MB, Venditti E. Factors affecting the decline in incidence of diabetes in the Diabetes Prevention Program Outcomes Study (DPPOS). Diabetes. 2015 Mar; 64(3):989-98. PMID: 25277389; PMCID: PMC4338587.
    Citations: 10     Fields:    Translation:Humans
  32. Espeland MA, Glick HA, Bertoni A, Brancati FL, Bray GA, Clark JM, Curtis JM, Egan C, Evans M, Foreyt JP, Ghazarian S, Gregg EW, Hazuda HP, Hill JO, Hire D, Horton ES, Hubbard VS, Jakicic JM, Jeffery RW, Johnson KC, Kahn SE, Killean T, Kitabchi AE, Knowler WC, Kriska A, Lewis CE, Miller M, Montez MG, Murillo A, Nathan DM, Nyenwe E, Patricio J, Peters AL, Pi-Sunyer X, Pownall H, Redmon JB, Rushing J, Ryan DH, Safford M, Tsai AG, Wadden TA, Wing RR, Yanovski SZ, Zhang P. Impact of an intensive lifestyle intervention on use and cost of medical services among overweight and obese adults with type 2 diabetes: the action for health in diabetes. Diabetes Care. 2014 Sep; 37(9):2548-56. PMID: 25147253; PMCID: PMC4140155.
    Citations: 40     Fields:    Translation:Humans
  33. Nicklas JM, Zera CA, England LJ, Rosner BA, Horton E, Levkoff SE, Seely EW. A web-based lifestyle intervention for women with recent gestational diabetes mellitus: a randomized controlled trial. Obstet Gynecol. 2014 Sep; 124(3):563-70. PMID: 25162257; PMCID: PMC4401073.
    Citations: 17     Fields:    Translation:Humans
  34. Rubin RR, Wadden TA, Bahnson JL, Blackburn GL, Brancati FL, Bray GA, Coday M, Crow SJ, Curtis JM, Dutton G, Egan C, Evans M, Ewing L, Faulconbridge L, Foreyt J, Gaussoin SA, Gregg EW, Hazuda HP, Hill JO, Horton ES, Hubbard VS, Jakicic JM, Jeffery RW, Johnson KC, Kahn SE, Knowler WC, Lang W, Lewis CE, Montez MG, Murillo A, Nathan DM, Patricio J, Peters A, Pi-Sunyer X, Pownall H, Rejeski WJ, Rosenthal RH, Ruelas V, Toledo K, Van Dorsten B, Vitolins M, Williamson D, Wing RR, Yanovski SZ, Zhang P. Impact of intensive lifestyle intervention on depression and health-related quality of life in type 2 diabetes: the Look AHEAD Trial. Diabetes Care. 2014 Jun; 37(6):1544-53. PMID: 24855155; PMCID: PMC4030096.
    Citations: 36     Fields:    Translation:Humans
  35. Walford GA, Ma Y, Christophi CA, Goldberg RB, Jarolim P, Horton E, Mather KJ, Barrett-Connor E, Davis J, Florez JC, Wang TJ. Circulating natriuretic peptide concentrations reflect changes in insulin sensitivity over time in the Diabetes Prevention Program. Diabetologia. 2014 May; 57(5):935-9. PMID: 24554005; PMCID: PMC4158711.
    Citations: 3     Fields:    Translation:Humans
  36. Zanobetti A, Luttmann-Gibson H, Horton ES, Cohen A, Coull BA, Hoffmann B, Schwartz JD, Mittleman MA, Li Y, Stone PH, de Souza C, Lamparello B, Koutrakis P, Gold DR. Brachial artery responses to ambient pollution, temperature, and humidity in people with type 2 diabetes: a repeated-measures study. Environ Health Perspect. 2014 Mar; 122(3):242-8. PMID: 24398072; PMCID: PMC3948021.
    Citations: 12     Fields:    Translation:HumansPHPublic Health
  37. Sacks FM, Hermans MP, Fioretto P, Valensi P, Davis T, Horton E, Wanner C, Al-Rubeaan K, Aronson R, Barzon I, Bishop L, Bonora E, Bunnag P, Chuang LM, Deerochanawong C, Goldenberg R, Harshfield B, Hernández C, Herzlinger-Botein S, Itoh H, Jia W, Jiang YD, Kadowaki T, Laranjo N, Leiter L, Miwa T, Odawara M, Ohashi K, Ohno A, Pan C, Pan J, Pedro-Botet J, Reiner Z, Rotella CM, Simo R, Tanaka M, Tedeschi-Reiner E, Twum-Barima D, Zoppini G, Carey VJ. Association between plasma triglycerides and high-density lipoprotein cholesterol and microvascular kidney disease and retinopathy in type 2 diabetes mellitus: a global case-control study in 13 countries. Circulation. 2014 Mar 04; 129(9):999-1008. PMID: 24352521.
    Citations: 41     Fields:    Translation:Humans
  38. Shen L, Shah BR, Reyes EM, Thomas L, Wojdyla D, Diem P, Leiter LA, Charbonnel B, Mareev V, Horton ES, Haffner SM, Soska V, Holman R, Bethel MA, Schaper F, Sun JL, McMurray JJ, Califf RM, Krum H. Role of diuretics, ß blockers, and statins in increasing the risk of diabetes in patients with impaired glucose tolerance: reanalysis of data from the NAVIGATOR study. BMJ. 2013 Dec 09; 347:f6745. PMID: 24322398; PMCID: PMC3898638.
    Citations: 21     Fields:    Translation:Humans
  39. Franks PW, Christophi CA, Jablonski KA, Billings LK, Delahanty LM, Horton ES, Knowler WC, Florez JC. Common variation at PPARGC1A/B and change in body composition and metabolic traits following preventive interventions: the Diabetes Prevention Program. Diabetologia. 2014 Mar; 57(3):485-90. PMID: 24317794; PMCID: PMC4154629.
    Citations: 5     Fields:    Translation:Humans
  40. Mendivil CO, Robles-Osorio L, Horton ES, Hamdy O, Caballero AE. Young Hispanics at risk of type 2 diabetes display endothelial activation, subclinical inflammation and alterations of coagulation and fibrinolysis. Diabetol Metab Syndr. 2013 Jul 19; 5(1):37. PMID: 23870459; PMCID: PMC3733973.
    Citations: 4     
  41. Wing RR, Bolin P, Brancati FL, Bray GA, Clark JM, Coday M, Crow RS, Curtis JM, Egan CM, Espeland MA, Evans M, Foreyt JP, Ghazarian S, Gregg EW, Harrison B, Hazuda HP, Hill JO, Horton ES, Hubbard VS, Jakicic JM, Jeffery RW, Johnson KC, Kahn SE, Kitabchi AE, Knowler WC, Lewis CE, Maschak-Carey BJ, Montez MG, Murillo A, Nathan DM, Patricio J, Peters A, Pi-Sunyer X, Pownall H, Reboussin D, Regensteiner JG, Rickman AD, Ryan DH, Safford M, Wadden TA, Wagenknecht LE, West DS, Williamson DF, Yanovski SZ. Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med. 2013 Jul 11; 369(2):145-54. PMID: 23796131.
    Citations: 429     Fields:    Translation:Humans
  42. Espeland MA, Rejeski WJ, West DS, Bray GA, Clark JM, Peters AL, Chen H, Johnson KC, Horton ES, Hazuda HP. Intensive weight loss intervention in older individuals: results from the Action for Health in Diabetes Type 2 diabetes mellitus trial. J Am Geriatr Soc. 2013 Jun; 61(6):912-22. PMID: 23668423; PMCID: PMC4123658.
    Citations: 10     Fields:    Translation:Humans
  43. Dobs AS, Goldstein BJ, Aschner P, Horton ES, Umpierrez GE, Duran L, Hill JS, Chen Y, Golm GT, Langdon RB, Williams-Herman DE, Kaufman KD, Amatruda JM, Ferreira JC. Efficacy and safety of sitagliptin added to ongoing metformin and rosiglitazone combination therapy in a randomized placebo-controlled 54-week trial in patients with type 2 diabetes. J Diabetes. 2013 Mar; 5(1):68-79. PMID: 22742523.
    Citations: 16     Fields:    Translation:Humans
  44. Herzlinger S, Horton ES. Extraglycemic effects of glp-1-based therapeutics: addressing metabolic and cardiovascular risks associated with type 2 diabetes. Diabetes Res Clin Pract. 2013 Apr; 100(1):1-10. PMID: 23332049.
    Citations: 3     Fields:    Translation:Humans
  45. Ribisl PM, Gaussoin SA, Lang W, Bahnson J, Connelly SA, Horton ES, Jakicic JM, Killean T, Kitzman DW, Knowler WC, Stewart KJ. Lifestyle intervention improves heart rate recovery from exercise in adults with type 2 diabetes: results from the Look AHEAD study. J Obes. 2012; 2012:309196. PMID: 23227314; PMCID: PMC3512322.
    Citations: 7     Fields:    Translation:Humans
  46. Freeman JS, Horton ES. What have we learned about the treatment of type 2 diabetes? The evolving paradigms. Am J Ther. 2012 Nov; 19(6):449-64. PMID: 23154228.
    Citations: 1     Fields:    Translation:HumansAnimals
  47. Florez JC, Jablonski KA, McAteer JB, Franks PW, Mason CC, Mather K, Horton E, Goldberg R, Dabelea D, Kahn SE, Arakaki RF, Shuldiner AR, Knowler WC. Effects of genetic variants previously associated with fasting glucose and insulin in the Diabetes Prevention Program. PLoS One. 2012; 7(9):e44424. PMID: 22984506; PMCID: PMC3439414.
    Citations: 11     Fields:    Translation:Humans
  48. Pollin TI, Isakova T, Jablonski KA, de Bakker PI, Taylor A, McAteer J, Pan Q, Horton ES, Delahanty LM, Altshuler D, Shuldiner AR, Goldberg RB, Florez JC, Franks PW. Genetic modulation of lipid profiles following lifestyle modification or metformin treatment: the Diabetes Prevention Program. PLoS Genet. 2012; 8(8):e1002895. PMID: 22951888; PMCID: PMC3431328.
    Citations: 14     Fields:    Translation:Humans
  49. Florez JC, Jablonski KA, Taylor A, Mather K, Horton E, White NH, Barrett-Connor E, Knowler WC, Shuldiner AR, Pollin TI. The C allele of ATM rs11212617 does not associate with metformin response in the Diabetes Prevention Program. Diabetes Care. 2012 Sep; 35(9):1864-7. PMID: 22751958; PMCID: PMC3425006.
    Citations: 18     Fields:    Translation:Humans
  50. Fields J, Trivedi NJ, Horton E, Mechanick JI. Vitamin D in the Persian Gulf: integrative physiology and socioeconomic factors. Curr Osteoporos Rep. 2011 Dec; 9(4):243-50. PMID: 21901427.
    Citations: 16     Fields:    Translation:Humans
  51. Hoffmann B, Luttmann-Gibson H, Cohen A, Zanobetti A, de Souza C, Foley C, Suh HH, Coull BA, Schwartz J, Mittleman M, Stone P, Horton E, Gold DR. Opposing effects of particle pollution, ozone, and ambient temperature on arterial blood pressure. Environ Health Perspect. 2012 Feb; 120(2):241-6. PMID: 22020729; PMCID: PMC3279434.
    Citations: 45     Fields:    Translation:Humans
  52. Hamdy O, Horton ES. Protein content in diabetes nutrition plan. Curr Diab Rep. 2011 Apr; 11(2):111-9. PMID: 21207203.
    Citations: 1     Fields:    Translation:Humans
  53. Handelsman Y, Mechanick JI, Blonde L, Grunberger G, Bloomgarden ZT, Bray GA, Dagogo-Jack S, Davidson JA, Einhorn D, Ganda O, Garber AJ, Hirsch IB, Horton ES, Ismail-Beigi F, Jellinger PS, Jones KL, Jovanovic L, Lebovitz H, Levy P, Moghissi ES, Orzeck EA, Vinik AI, Wyne KL. American Association of Clinical Endocrinologists Medical Guidelines for clinical practice for developing a diabetes mellitus comprehensive care plan: executive summary. Endocr Pract. 2011 Mar-Apr; 17(2):287-302. PMID: 21474421.
    Citations: 25     Fields:    Translation:Humans
  54. Handelsman Y, Mechanick JI, Blonde L, Grunberger G, Bloomgarden ZT, Bray GA, Dagogo-Jack S, Davidson JA, Einhorn D, Ganda O, Garber AJ, Hirsch IB, Horton ES, Ismail-Beigi F, Jellinger PS, Jones KL, Jovanovic L, Lebovitz H, Levy P, Moghissi ES, Orzeck EA, Vinik AI, Wyne KL. American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for developing a diabetes mellitus comprehensive care plan. Endocr Pract. 2011 Mar-Apr; 17 Suppl 2:1-53. PMID: 21474420.
    Citations: 101     Fields:    Translation:Humans
  55. Horton ES, Silberman C, Davis KL, Berria R. Weight loss, glycemic control, and changes in cardiovascular biomarkers in patients with type 2 diabetes receiving incretin therapies or insulin in a large cohort database. Diabetes Care. 2010 Aug; 33(8):1759-65. PMID: 20460445; PMCID: PMC2909058.
    Citations: 33     Fields:    Translation:Humans
  56. Davis SN, Horton ES, Battelino T, Rubin RR, Schulman KA, Tamborlane WV. STAR 3 randomized controlled trial to compare sensor-augmented insulin pump therapy with multiple daily injections in the treatment of type 1 diabetes: research design, methods, and baseline characteristics of enrolled subjects. Diabetes Technol Ther. 2010 Apr; 12(4):249-55. PMID: 20210562; PMCID: PMC2883476.
    Citations: 11     Fields:    Translation:Humans
  57. McMurray JJ, Holman RR, Haffner SM, Bethel MA, Holzhauer B, Hua TA, Belenkov Y, Boolell M, Buse JB, Buckley BM, Chacra AR, Chiang FT, Charbonnel B, Chow CC, Davies MJ, Deedwania P, Diem P, Einhorn D, Fonseca V, Fulcher GR, Gaciong Z, Gaztambide S, Giles T, Horton E, Ilkova H, Jenssen T, Kahn SE, Krum H, Laakso M, Leiter LA, Levitt NS, Mareev V, Martinez F, Masson C, Mazzone T, Meaney E, Nesto R, Pan C, Prager R, Raptis SA, Rutten GE, Sandstroem H, Schaper F, Scheen A, Schmitz O, Sinay I, Soska V, Stender S, Tamás G, Tognoni G, Tuomilehto J, Villamil AS, Vozár J, Califf RM. Effect of valsartan on the incidence of diabetes and cardiovascular events. N Engl J Med. 2010 Apr 22; 362(16):1477-90. PMID: 20228403.
    Citations: 139     Fields:    Translation:Humans
  58. Holman RR, Haffner SM, McMurray JJ, Bethel MA, Holzhauer B, Hua TA, Belenkov Y, Boolell M, Buse JB, Buckley BM, Chacra AR, Chiang FT, Charbonnel B, Chow CC, Davies MJ, Deedwania P, Diem P, Einhorn D, Fonseca V, Fulcher GR, Gaciong Z, Gaztambide S, Giles T, Horton E, Ilkova H, Jenssen T, Kahn SE, Krum H, Laakso M, Leiter LA, Levitt NS, Mareev V, Martinez F, Masson C, Mazzone T, Meaney E, Nesto R, Pan C, Prager R, Raptis SA, Rutten GE, Sandstroem H, Schaper F, Scheen A, Schmitz O, Sinay I, Soska V, Stender S, Tamás G, Tognoni G, Tuomilehto J, Villamil AS, Vozár J, Califf RM. Effect of nateglinide on the incidence of diabetes and cardiovascular events. N Engl J Med. 2010 Apr 22; 362(16):1463-76. PMID: 20228402.
    Citations: 100     Fields:    Translation:Humans
  59. Krum H, McMurray JJ, Horton E, Gerlock T, Holzhauer B, Zuurman L, Haffner SM, Bethel MA, Holman RR, Califf RM. Baseline characteristics of the Nateglinide and Valsartan Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) trial population: comparison with other diabetes prevention trials. Cardiovasc Ther. 2010 Apr; 28(2):124-32. PMID: 20184589.
    Citations: 3     Fields:    Translation:Humans
  60. Henderson GC, Nadeau D, Horton ES, Nair KS. Effects of adiposity and 30 days of caloric restriction upon protein metabolism in moderately vs. severely obese women. Obesity (Silver Spring). 2010 Jun; 18(6):1135-42. PMID: 20134416; PMCID: PMC2877146.
    Citations: 6     Fields:    Translation:HumansCellsCTClinical Trials
  61. Horton ES. Challenges and approaches to managing type 2 diabetes mellitus. Curr Diab Rep. 2010 Feb; 10(1):7-9. PMID: 20425060.
    Citations:    Fields:    Translation:Humans
  62. Curtis JM, Horton ES, Bahnson J, Gregg EW, Jakicic JM, Regensteiner JG, Ribisl PM, Soberman JE, Stewart KJ, Espeland MA. Prevalence and predictors of abnormal cardiovascular responses to exercise testing among individuals with type 2 diabetes: the Look AHEAD (Action for Health in Diabetes) study. Diabetes Care. 2010 Apr; 33(4):901-7. PMID: 20056948; PMCID: PMC2845049.
    Citations: 5     Fields:    Translation:Humans
  63. Horton ES. Effects of lifestyle changes to reduce risks of diabetes and associated cardiovascular risks: results from large scale efficacy trials. Obesity (Silver Spring). 2009 Dec; 17 Suppl 3:S43-8. PMID: 19927146.
    Citations: 24     Fields:    Translation:Humans
  64. Rodbard HW, Jellinger PS, Davidson JA, Einhorn D, Garber AJ, Grunberger G, Handelsman Y, Horton ES, Lebovitz H, Levy P, Moghissi ES, Schwartz SS. Statement by an American Association of Clinical Endocrinologists/American College of Endocrinology consensus panel on type 2 diabetes mellitus: an algorithm for glycemic control. Endocr Pract. 2009 Sep-Oct; 15(6):540-59. PMID: 19858063.
    Citations: 231     Fields:    Translation:Humans
  65. Jeremias A, Soodini G, Gelfand E, Xu Y, Stanton RC, Horton ES, Cohen DJ. Effects of N-acetyl-cysteine on endothelial function and inflammation in patients with type 2 diabetes mellitus. Heart Int. 2009 Jun 30; 4(1):e7. PMID: 21977284.
    Citations: 2     
  66. Horton ES. Defining the role of basal and prandial insulin for optimal glycemic control. J Am Coll Cardiol. 2009 Feb 03; 53(5 Suppl):S21-7. PMID: 19179213.
    Citations: 3     Fields:    Translation:HumansCells
  67. Garber AJ, Handelsman Y, Einhorn D, Bergman DA, Bloomgarden ZT, Fonseca V, Garvey WT, Gavin JR, Grunberger G, Horton ES, Jellinger PS, Jones KL, Lebovitz H, Levy P, McGuire DK, Moghissi ES, Nesto RW. Diagnosis and management of prediabetes in the continuum of hyperglycemia: when do the risks of diabetes begin? A consensus statement from the American College of Endocrinology and the American Association of Clinical Endocrinologists. Endocr Pract. 2008 Oct; 14(7):933-46. PMID: 18996826.
    Citations: 39     Fields:    Translation:Humans
  68. Friedman AN, Friedman A, Marrero D, Ma Y, Ackermann R, Narayan KM, Barrett-Connor E, Watson K, Knowler WC, Horton ES. Value of urinary albumin-to-creatinine ratio as a predictor of type 2 diabetes in pre-diabetic individuals. Diabetes Care. 2008 Dec; 31(12):2344-8. PMID: 18796622; PMCID: PMC2584193.
    Citations: 10     Fields:    Translation:Humans
  69. Rosenzweig JL, Ferrannini E, Grundy SM, Haffner SM, Heine RJ, Horton ES, Kawamori R. Primary prevention of cardiovascular disease and type 2 diabetes in patients at metabolic risk: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2008 Oct; 93(10):3671-89. PMID: 18664543.
    Citations: 39     Fields:    Translation:Humans
  70. Orasanu G, Ziouzenkova O, Devchand PR, Nehra V, Hamdy O, Horton ES, Plutzky J. The peroxisome proliferator-activated receptor-gamma agonist pioglitazone represses inflammation in a peroxisome proliferator-activated receptor-alpha-dependent manner in vitro and in vivo in mice. J Am Coll Cardiol. 2008 Sep 02; 52(10):869-81. PMID: 18755353; PMCID: PMC2633943.
    Citations: 25     Fields:    Translation:HumansAnimalsCTClinical Trials
  71. Horton E, Cefalu WT, Haines ST, Siminerio LM. Multidisciplinary interventions: mapping new horizons in diabetes care. Diabetes Educ. 2008 Jul-Aug; 34 Suppl 4:78S-89S. PMID: 18664711.
    Citations: 1     Fields:    Translation:Humans
  72. Horton ES. Can newer therapies delay the progression of type 2 diabetes mellitus? Endocr Pract. 2008 Jul-Aug; 14(5):625-38. PMID: 18753109.
    Citations: 5     Fields:    Translation:Humans
  73. Perreault L, Ma Y, Dagogo-Jack S, Horton E, Marrero D, Crandall J, Barrett-Connor E. Sex differences in diabetes risk and the effect of intensive lifestyle modification in the Diabetes Prevention Program. Diabetes Care. 2008 Jul; 31(7):1416-21. PMID: 18356403; PMCID: PMC2453677.
    Citations: 27     Fields:    Translation:Humans
  74. Caballero AE, Bousquet-Santos K, Robles-Osorio L, Montagnani V, Soodini G, Porramatikul S, Hamdy O, Nobrega AC, Horton ES. Overweight Latino children and adolescents have marked endothelial dysfunction and subclinical vascular inflammation in association with excess body fat and insulin resistance. Diabetes Care. 2008 Mar; 31(3):576-82. PMID: 18083792.
    Citations: 31     Fields:    Translation:Humans
  75. Herman WH, Ma Y, Uwaifo G, Haffner S, Kahn SE, Horton ES, Lachin JM, Montez MG, Brenneman T, Barrett-Connor E. Differences in A1C by race and ethnicity among patients with impaired glucose tolerance in the Diabetes Prevention Program. Diabetes Care. 2007 Oct; 30(10):2453-7. PMID: 17536077; PMCID: PMC2373980.
    Citations: 152     Fields:    Translation:Humans
  76. Cohen A, Horton ES. Progress in the treatment of type 2 diabetes: new pharmacologic approaches to improve glycemic control. Curr Med Res Opin. 2007 Apr; 23(4):905-17. PMID: 17407648.
    Citations: 15     Fields:    Translation:Humans
  77. Pi-Sunyer X, Blackburn G, Brancati FL, Bray GA, Bright R, Clark JM, Curtis JM, Espeland MA, Foreyt JP, Graves K, Haffner SM, Harrison B, Hill JO, Horton ES, Jakicic J, Jeffery RW, Johnson KC, Kahn S, Kelley DE, Kitabchi AE, Knowler WC, Lewis CE, Maschak-Carey BJ, Montgomery B, Nathan DM, Patricio J, Peters A, Redmon JB, Reeves RS, Ryan DH, Safford M, Van Dorsten B, Wadden TA, Wagenknecht L, Wesche-Thobaben J, Wing RR, Yanovski SZ. Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the look AHEAD trial. Diabetes Care. 2007 Jun; 30(6):1374-83. PMID: 17363746; PMCID: PMC2665929.
    Citations: 414     Fields:    Translation:Humans
  78. Middelbeek RJ, Horton ES. The role of glucose as an independent cardiovascular risk factor. Curr Diab Rep. 2007 Feb; 7(1):43-9. PMID: 17254517.
    Citations: 1     Fields:    Translation:Humans
  79. O'Neill MS, Veves A, Sarnat JA, Zanobetti A, Gold DR, Economides PA, Horton ES, Schwartz J. Air pollution and inflammation in type 2 diabetes: a mechanism for susceptibility. Occup Environ Med. 2007 Jun; 64(6):373-9. PMID: 17182639; PMCID: PMC2078522.
    Citations: 77     Fields:    Translation:HumansPHPublic Health
  80. Al-Ozairi E, Middelbeek RJ, Horton ES. Cardiovascular risk assessment in type 2 diabetes mellitus. Curr Diab Rep. 2006 Nov; 6(5):333-6. PMID: 17076992.
    Citations:    Fields:    Translation:Humans
  81. Kriska AM, Edelstein SL, Hamman RF, Otto A, Bray GA, Mayer-Davis EJ, Wing RR, Horton ES, Haffner SM, Regensteiner JG. Physical activity in individuals at risk for diabetes: Diabetes Prevention Program. Med Sci Sports Exerc. 2006 May; 38(5):826-32. PMID: 16672833; PMCID: PMC1570396.
    Citations: 23     Fields:    Translation:Humans
  82. Buras J, Reenstra WR, Orlow D, Horton ES, Veves A. Troglitazone-induced changes in adiponectin do not affect endothelial function in diabetes. Obes Res. 2005 Jul; 13(7):1167-74. PMID: 16076985.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  83. O'Neill MS, Veves A, Zanobetti A, Sarnat JA, Gold DR, Economides PA, Horton ES, Schwartz J. Diabetes enhances vulnerability to particulate air pollution-associated impairment in vascular reactivity and endothelial function. Circulation. 2005 Jun 07; 111(22):2913-20. PMID: 15927967.
    Citations: 135     Fields:    Translation:HumansPHPublic Health
  84. Haffner S, Temprosa M, Crandall J, Fowler S, Goldberg R, Horton E, Marcovina S, Mather K, Orchard T, Ratner R, Barrett-Connor E. Intensive lifestyle intervention or metformin on inflammation and coagulation in participants with impaired glucose tolerance. Diabetes. 2005 May; 54(5):1566-72. PMID: 15855347; PMCID: PMC1314967.
    Citations: 69     Fields:    Translation:HumansCTClinical Trials
  85. Economides PA, Khaodhiar L, Caselli A, Caballero AE, Keenan H, Bursell SE, King GL, Johnstone MT, Horton ES, Veves A. The effect of vitamin E on endothelial function of micro- and macrocirculation and left ventricular function in type 1 and type 2 diabetic patients. Diabetes. 2005 Jan; 54(1):204-11. PMID: 15616030.
    Citations: 17     Fields:    Translation:HumansCTClinical Trials
  86. Shetty GK, Economides PA, Horton ES, Mantzoros CS, Veves A. Circulating adiponectin and resistin levels in relation to metabolic factors, inflammatory markers, and vascular reactivity in diabetic patients and subjects at risk for diabetes. Diabetes Care. 2004 Oct; 27(10):2450-7. PMID: 15451915.
    Citations: 82     Fields:    Translation:HumansCTClinical Trials
  87. Wing RR, Hamman RF, Bray GA, Delahanty L, Edelstein SL, Hill JO, Horton ES, Hoskin MA, Kriska A, Lachin J, Mayer-Davis EJ, Pi-Sunyer X, Regensteiner JG, Venditti B, Wylie-Rosett J. Achieving weight and activity goals among diabetes prevention program lifestyle participants. Obes Res. 2004 Sep; 12(9):1426-34. PMID: 15483207; PMCID: PMC2505058.
    Citations: 173     Fields:    Translation:HumansCTClinical Trials
  88. Steppel JH, Horton ES. Beta-cell failure in the pathogenesis of type 2 diabetes mellitus. Curr Diab Rep. 2004 Jun; 4(3):169-75. PMID: 15132880.
    Citations: 6     Fields:    Translation:Humans
  89. Horton ES, Foley JE, Shen SG, Baron MA. Efficacy and tolerability of initial combination therapy with nateglinide and metformin in treatment-naïve patients with type 2 diabetes. Curr Med Res Opin. 2004 Jun; 20(6):883-9. PMID: 15200747.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  90. Heine RJ, Balkau B, Ceriello A, Del Prato S, Horton ES, Taskinen MR. What does postprandial hyperglycaemia mean? Diabet Med. 2004 Mar; 21(3):208-13. PMID: 15008828.
    Citations: 21     Fields:    Translation:Humans
  91. Economides PA, Caselli A, Tiani E, Khaodhiar L, Horton ES, Veves A. The effects of atorvastatin on endothelial function in diabetic patients and subjects at risk for type 2 diabetes. J Clin Endocrinol Metab. 2004 Feb; 89(2):740-7. PMID: 14764790.
    Citations: 25     Fields:    Translation:HumansCTClinical Trials
  92. Economides PA, Caselli A, Zuo CS, Sparks C, Khaodhiar L, Katsilambros N, Horton ES, Veves A. Kidney oxygenation during water diuresis and endothelial function in patients with type 2 diabetes and subjects at risk to develop diabetes. Metabolism. 2004 Feb; 53(2):222-7. PMID: 14767875.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  93. Nesto RW, Bell D, Bonow RO, Fonseca V, Grundy SM, Horton ES, Le Winter M, Porte D, Semenkovich CF, Smith S, Young LH, Kahn R. Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association. Diabetes Care. 2004 Jan; 27(1):256-63. PMID: 14693998.
    Citations: 100     Fields:    Translation:Humans
  94. Nesto RW, Bell D, Bonow RO, Fonseca V, Grundy SM, Horton ES, Le Winter M, Porte D, Semenkovich CF, Smith S, Young LH, Kahn R. Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association. October 7, 2003. Circulation. 2003 Dec 09; 108(23):2941-8. PMID: 14662691.
    Citations: 163     Fields:    Translation:Humans
  95. Steppel JH, Horton ES. Exercise in the management of type 1 diabetes mellitus. Rev Endocr Metab Disord. 2003 Dec; 4(4):355-60. PMID: 14618020.
    Citations: 6     Fields:    Translation:Humans
  96. Monzillo LU, Hamdy O, Horton ES, Ledbury S, Mullooly C, Jarema C, Porter S, Ovalle K, Moussa A, Mantzoros CS. Effect of lifestyle modification on adipokine levels in obese subjects with insulin resistance. Obes Res. 2003 Sep; 11(9):1048-54. PMID: 12972674.
    Citations: 75     Fields:    Translation:Humans
  97. Hamdy O, Ledbury S, Mullooly C, Jarema C, Porter S, Ovalle K, Moussa A, Caselli A, Caballero AE, Economides PA, Veves A, Horton ES. Lifestyle modification improves endothelial function in obese subjects with the insulin resistance syndrome. Diabetes Care. 2003 Jul; 26(7):2119-25. PMID: 12832323.
    Citations: 67     Fields:    Translation:Humans
  98. Varo N, Vicent D, Libby P, Nuzzo R, Calle-Pascual AL, Bernal MR, Fernández-Cruz A, Veves A, Jarolim P, Varo JJ, Goldfine A, Horton E, Schönbeck U. Elevated plasma levels of the atherogenic mediator soluble CD40 ligand in diabetic patients: a novel target of thiazolidinediones. Circulation. 2003 Jun 03; 107(21):2664-9. PMID: 12742991.
    Citations: 30     Fields:    Translation:HumansCTClinical Trials
  99. Caballero AE, Saouaf R, Lim SC, Hamdy O, Abou-Elenin K, O'Connor C, Logerfo FW, Horton ES, Veves A. The effects of troglitazone, an insulin-sensitizing agent, on the endothelial function in early and late type 2 diabetes: a placebo-controlled randomized clinical trial. Metabolism. 2003 Feb; 52(2):173-80. PMID: 12601628.
    Citations: 26     Fields:    Translation:HumansCTClinical Trials
  100. Szabó C, Zanchi A, Komjáti K, Pacher P, Krolewski AS, Quist WC, LoGerfo FW, Horton ES, Veves A. Poly(ADP-Ribose) polymerase is activated in subjects at risk of developing type 2 diabetes and is associated with impaired vascular reactivity. Circulation. 2002 Nov 19; 106(21):2680-6. PMID: 12438293.
    Citations: 55     Fields:    Translation:HumansCellsCTClinical Trials
  101. Abou-Elenin K, Xydakis A, Hamdy O, Economides PA, Horton ES, Veves A. The effect of aspirin and various iontophoresis solution vehicles on skin microvascular reactivity. Microvasc Res. 2002 Jan; 63(1):91-5. PMID: 11749076.
    Citations: 2     Fields:    Translation:Humans
  102. Matarazzo M, Giardina MG, Guardasole V, Davalli AM, Horton ES, Weir GC, Saccà L, Napoli R. Islet transplantation under the kidney capsule corrects the defects in glycogen metabolism in both liver and muscle of streptozocin-diabetic rats. Cell Transplant. 2002; 11(2):103-12. PMID: 12099634.
    Citations: 1     Fields:    Translation:Animals
  103. Hamdy O, Goodyear LJ, Horton ES. Diet and exercise in type 2 diabetes mellitus. Endocrinol Metab Clin North Am. 2001 Dec; 30(4):883-907. PMID: 11727404.
    Citations: 17     Fields:    Translation:Humans
  104. Hamdy O, Abou-Elenin K, LoGerfo FW, Horton ES, Veves A. Contribution of nerve-axon reflex-related vasodilation to the total skin vasodilation in diabetic patients with and without neuropathy. Diabetes Care. 2001 Feb; 24(2):344-9. PMID: 11213890.
    Citations: 19     Fields:    Translation:HumansCells
  105. Horton ES, Clinkingbeard C, Gatlin M, Foley J, Mallows S, Shen S. Nateglinide alone and in combination with metformin improves glycemic control by reducing mealtime glucose levels in type 2 diabetes. Diabetes Care. 2000 Nov; 23(11):1660-5. PMID: 11092289.
    Citations: 26     Fields:    Translation:HumansCTClinical Trials
  106. Stellato RK, Feldman HA, Hamdy O, Horton ES, McKinlay JB. Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men: prospective results from the Massachusetts male aging study. Diabetes Care. 2000 Apr; 23(4):490-4. PMID: 10857940.
    Citations: 105     Fields:    Translation:Humans
  107. Lim SC, Caballero AE, Arora S, Smakowski P, Bashoff EM, Brown FM, Logerfo FW, Horton ES, Veves A. The effect of hormonal replacement therapy on the vascular reactivity and endothelial function of healthy individuals and individuals with type 2 diabetes. J Clin Endocrinol Metab. 1999 Nov; 84(11):4159-64. PMID: 10566666.
    Citations: 8     Fields:    Translation:Humans
  108. Lim SC, Caballero AE, Smakowski P, LoGerfo FW, Horton ES, Veves A. Soluble intercellular adhesion molecule, vascular cell adhesion molecule, and impaired microvascular reactivity are early markers of vasculopathy in type 2 diabetic individuals without microalbuminuria. Diabetes Care. 1999 Nov; 22(11):1865-70. PMID: 10546021.
    Citations: 23     Fields:    Translation:Humans
  109. Caballero AE, Arora S, Saouaf R, Lim SC, Smakowski P, Park JY, King GL, LoGerfo FW, Horton ES, Veves A. Microvascular and macrovascular reactivity is reduced in subjects at risk for type 2 diabetes. Diabetes. 1999 Sep; 48(9):1856-62. PMID: 10480619.
    Citations: 113     Fields:    Translation:Humans
  110. Kennedy JW, Hirshman MF, Gervino EV, Ocel JV, Forse RA, Hoenig SJ, Aronson D, Goodyear LJ, Horton ES. Acute exercise induces GLUT4 translocation in skeletal muscle of normal human subjects and subjects with type 2 diabetes. Diabetes. 1999 May; 48(5):1192-7. PMID: 10331428.
    Citations: 57     Fields:    Translation:HumansCells
  111. Giorgino F, Logoluso F, Davalli AM, Napoli R, Laviola L, Hirshman MF, Horton ES, Weir GC, Smith RJ. Islet transplantation restores normal levels of insulin receptor and substrate tyrosine phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle and myocardium of streptozocin-induced diabetic rats. Diabetes. 1999 Apr; 48(4):801-12. PMID: 10102697.
    Citations: 5     Fields:    Translation:AnimalsCells
  112. Napoli R, Gibson L, Hirshman MF, Boppart MD, Dufresne SD, Horton ES, Goodyear LJ. Epinephrine and insulin stimulate different mitogen-activated protein kinase signaling pathways in rat skeletal muscle. Diabetes. 1998 Oct; 47(10):1549-54. PMID: 9753291.
    Citations: 9     Fields:    Translation:AnimalsCells
  113. Horton ES, Whitehouse F, Ghazzi MN, Venable TC, Whitcomb RW. Troglitazone in combination with sulfonylurea restores glycemic control in patients with type 2 diabetes. The Troglitazone Study Group. Diabetes Care. 1998 Sep; 21(9):1462-9. PMID: 9727892.
    Citations: 15     Fields:    Translation:HumansCTClinical Trials
  114. Veves A, Saouaf R, Donaghue VM, Mullooly CA, Kistler JA, Giurini JM, Horton ES, Fielding RA. Aerobic exercise capacity remains normal despite impaired endothelial function in the micro- and macrocirculation of physically active IDDM patients. Diabetes. 1997 Nov; 46(11):1846-52. PMID: 9356035.
    Citations: 19     Fields:    Translation:Humans
  115. de Souza CJ, Hirshman MF, Horton ES. CL-316,243, a beta3-specific adrenoceptor agonist, enhances insulin-stimulated glucose disposal in nonobese rats. Diabetes. 1997 Aug; 46(8):1257-63. PMID: 9231648.
    Citations: 21     Fields:    Translation:Animals
  116. Goodyear LJ, Hirshman MF, Napoli R, Calles J, Markuns JF, Ljungqvist O, Horton ES. Glucose ingestion causes GLUT4 translocation in human skeletal muscle. Diabetes. 1996 Aug; 45(8):1051-6. PMID: 8690151.
    Citations: 4     Fields:    Translation:HumansCells
  117. Davalli AM, Napoli R, Weitgasser R, Capotorto JV, Hirshman MF, Finegood DT, Bonner-Weir S, Horton ES, Weir GC. Long-term normalization of GLUT-4 protein content in skeletal muscle of diabetic rats following islet transplantation. J Endocrinol. 1996 Aug; 150(2):255-63. PMID: 8869592.
    Citations:    Fields:    Translation:Animals
  118. Napoli R, Cittadini A, Chow JC, Hirshman MF, Smith RJ, Douglas PS, Horton ES. Chronic growth hormone treatment in normal rats reduces post-prandial skeletal muscle plasma membrane GLUT1 content, but not glucose transport or GLUT4 expression and localization. Biochem J. 1996 May 01; 315 ( Pt 3):959-63. PMID: 8645183; PMCID: PMC1217300.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  119. Napoli R, Davalli AM, Hirshman MF, Weitgasser R, Weir GC, Horton ES. Islet transplantation under the kidney capsule fully corrects the impaired skeletal muscle glucose transport system of streptozocin diabetic rats. J Clin Invest. 1996 Mar 15; 97(6):1389-97. PMID: 8617870; PMCID: PMC507197.
    Citations: 6     Fields:    Translation:Animals
  120. Napoli R, Hirshman MF, Horton ES. Mechanisms of increased skeletal muscle glucose transport activity after an oral glucose load in rats. Diabetes. 1995 Dec; 44(12):1362-8. PMID: 7589839.
    Citations:    Fields:    Translation:AnimalsCells
  121. Horton ES. NIDDM--the devastating disease. Diabetes Res Clin Pract. 1995 Aug; 28 Suppl:S3-11. PMID: 8529517.
    Citations: 6     Fields:    Translation:Humans
  122. Napoli R, Hirshman MF, Horton ES. Mechanisms and time course of impaired skeletal muscle glucose transport activity in streptozocin diabetic rats. J Clin Invest. 1995 Jul; 96(1):427-37. PMID: 7615815; PMCID: PMC185216.
    Citations: 8     Fields:    Translation:Animals
  123. Franz MJ, Horton ES, Bantle JP, Beebe CA, Brunzell JD, Coulston AM, Henry RR, Hoogwerf BJ, Stacpoole PW. Nutrition principles for the management of diabetes and related complications. Diabetes Care. 1994 May; 17(5):490-518. PMID: 8062628.
    Citations: 17     Fields:    Translation:Humans
  124. Kahn BB, Horton ES, Cushman SW. Mechanism for enhanced glucose transport response to insulin in adipose cells from chronically hyperinsulinemic rats. Increased translocation of glucose transporters from an enlarged intracellular pool. J Clin Invest. 1987 Mar; 79(3):853-8. PMID: 3029179; PMCID: PMC424219.
    Citations: 7     Fields:    Translation:AnimalsCells
  125. Kelleher PC, Phinney SD, Sims EA, Bogardus C, Horton ES, Bistrian BR, Amatruda JM, Lockwood DH. Effects of carbohydrate-containing and carbohydrate-restricted hypocaloric and eucaloric diets on serum concentrations of retinol-binding protein, thyroxine-binding prealbumin and transferrin. Metabolism. 1983 Jan; 32(1):95-101. PMID: 6401350.
    Citations: 3     Fields:    Translation:HumansCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.