Harvard Catalyst Profiles

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Michael Eldon Greenberg, Ph.D.

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Mentoring
Characterization of Activity-dependent Phosphorylation of S86 on MeCP2
Summer, 05/31/10 - 08/13/10
Development of a Bacterial Two-Hybrid System to Study Phosphorylation-Dependent Protein Interactions in the CNS
Summer, 05/19/00 - 08/31/00

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. RF1MH114081 (GREENBERG, MICHAEL E) Aug 9, 2017 - Aug 8, 2020
    NIH/NIMH
    A General Approach for the Development of New Cell-Type-Specific Viral Vectors
    Role: Principal Investigator
  2. P30NS072030 (SABATINI, BERNARDO L) Sep 30, 2011 - Aug 31, 2021
    NIH/NINDS
    HMS/BCH Center for Neuroscience Research
    Role: Principal Investigator
  3. R01MH094663 (GREENBERG, MICHAEL E) Sep 1, 2011 - Jun 30, 2016
    NIH/NIMH
    Neuronal Epigenomic Changes in Neurodevelopment and Disease
    Role: Principal Investigator
  4. R01NS048276 (GREENBERG, MICHAEL E) Mar 1, 2004 - Jun 30, 2020
    NIH/NINDS
    Neuronal Activity-Dependent Regulation of MeCP2
    Role: Principal Investigator
  5. P01NS047572 (STILES, CHARLES) Dec 1, 2003 - Aug 31, 2014
    NIH/NINDS
    Molecular Mechanisms of Fate Choice in Neural Stem Cells (P01)
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Andzelm MM, Vanness D, Greenberg ME, Linden DJ. A Late Phase of Long-Term Synaptic Depression in Cerebellar Purkinje Cells Requires Activation of MEF2. Cell Rep. 2019 Jan 29; 26(5):1089-1097.e3. PMID: 30699340.
    Citations:    Fields:    
  2. Renthal W, Boxer LD, Hrvatin S, Li E, Silberfeld A, Nagy MA, Griffith EC, Vierbuchen T, Greenberg ME. Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing. Nat Neurosci. 2018 Dec; 21(12):1670-1679. PMID: 30455458.
    Citations:    Fields:    
  3. Yap EL, Greenberg ME. Activity-Regulated Transcription: Bridging the Gap between Neural Activity and Behavior. Neuron. 2018 Oct 24; 100(2):330-348. PMID: 30359600.
    Citations:    Fields:    
  4. Van Schil K, Naessens S, Van de Sompele S, Carron M, Aslanidis A, Van Cauwenbergh C, Mayer AK, Van Heetvelde M, Bauwens M, Verdin H, Coppieters F, Greenberg ME, Yang MG, Karlstetter M, Langmann T, De Preter K, Kohl S, Cherry TJ, Leroy BP, De Baere E. Correction: Mapping the genomic landscape of inherited retinal disease genes prioritizes genes prone to coding and noncoding copy-number variations. Genet Med. 2018 Oct 08. PMID: 30297699.
    Citations:    Fields:    
  5. Cheadle L, Tzeng CP, Kalish BT, Harmin DA, Rivera S, Ling E, Nagy MA, Hrvatin S, Hu L, Stroud H, Burkly LC, Chen C, Greenberg ME. Visual Experience-Dependent Expression of Fn14 Is Required for Retinogeniculate Refinement. Neuron. 2018 Aug 08; 99(3):525-539.e10. PMID: 30033152.
    Citations: 1     Fields:    
  6. Hrvatin S, Hochbaum DR, Nagy MA, Cicconet M, Robertson K, Cheadle L, Zilionis R, Ratner A, Borges-Monroy R, Klein AM, Sabatini BL, Greenberg ME. Publisher Correction: Single-cell analysis of experience-dependent transcriptomic states in the mouse visual cortex. Nat Neurosci. 2018 Jul; 21(7):1017. PMID: 29752482.
    Citations:    Fields:    
  7. Kalish BT, Cheadle L, Hrvatin S, Nagy MA, Rivera S, Crow M, Gillis J, Kirchner R, Greenberg ME. Single-cell transcriptomics of the developing lateral geniculate nucleus reveals insights into circuit assembly and refinement. Proc Natl Acad Sci U S A. 2018 01 30; 115(5):E1051-E1060. PMID: 29343640.
    Citations: 1     Fields:    Translation:AnimalsCells
  8. Vierbuchen T, Ling E, Cowley CJ, Couch CH, Wang X, Harmin DA, Roberts CWM, Greenberg ME. AP-1 Transcription Factors and the BAF Complex Mediate Signal-Dependent Enhancer Selection. Mol Cell. 2017 12 21; 68(6):1067-1082.e12. PMID: 29272704.
    Citations: 9     Fields:    Translation:AnimalsCells
  9. Hrvatin S, Hochbaum DR, Nagy MA, Cicconet M, Robertson K, Cheadle L, Zilionis R, Ratner A, Borges-Monroy R, Klein AM, Sabatini BL, Greenberg ME. Single-cell analysis of experience-dependent transcriptomic states in the mouse visual cortex. Nat Neurosci. 2018 Jan; 21(1):120-129. PMID: 29230054.
    Citations: 9     Fields:    
  10. Hardingham GE, Pruunsild P, Greenberg ME, Bading H. Lineage divergence of activity-driven transcription and evolution of cognitive ability. Nat Rev Neurosci. 2018 Jan; 19(1):9-15. PMID: 29167525.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  11. Stroud H, Su SC, Hrvatin S, Greben AW, Renthal W, Boxer LD, Nagy MA, Hochbaum DR, Kinde B, Gabel HW, Greenberg ME. Early-Life Gene Expression in Neurons Modulates Lasting Epigenetic States. Cell. 2017 Nov 16; 171(5):1151-1164.e16. PMID: 29056337.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  12. Susman MW, Karuna EP, Kunz RC, Gujral TS, Cantú AV, Choi SS, Jong BY, Okada K, Scales MK, Hum J, Hu LS, Kirschner MW, Nishinakamura R, Yamada S, Laird DJ, Jao LE, Gygi SP, Greenberg ME, Ho HH. Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates. Elife. 2017 09 08; 6. PMID: 28885975.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  13. Kamizaki K, Doi R, Hayashi M, Saji T, Kanagawa M, Toda T, Fukada SI, Ho HH, Greenberg ME, Endo M, Minami Y. The Ror1 receptor tyrosine kinase plays a critical role in regulating satellite cell proliferation during regeneration of injured muscle. J Biol Chem. 2017 09 22; 292(38):15939-15951. PMID: 28790171.
    Citations: 2     Fields:    Translation:AnimalsCells
  14. Van Schil K, Naessens S, Van de Sompele S, Carron M, Aslanidis A, Van Cauwenbergh C, Kathrin Mayer A, Van Heetvelde M, Bauwens M, Verdin H, Coppieters F, Greenberg ME, Yang MG, Karlstetter M, Langmann T, De Preter K, Kohl S, Cherry TJ, Leroy BP, De Baere E. Mapping the genomic landscape of inherited retinal disease genes prioritizes genes prone to coding and noncoding copy-number variations. Genet Med. 2018 02; 20(2):202-213. PMID: 28749477.
    Citations: 4     Fields:    Translation:HumansCells
  15. Hamilton AM, Lambert JT, Parajuli LK, Vivas O, Park DK, Stein IS, Jahncke JN, Greenberg ME, Margolis SS, Zito K. A dual role for the RhoGEF Ephexin5 in regulation of dendritic spine outgrowth. Mol Cell Neurosci. 2017 04; 80:66-74. PMID: 28185854.
    Citations: 1     Fields:    Translation:AnimalsCells
  16. Kinde B, Wu DY, Greenberg ME, Gabel HW. DNA methylation in the gene body influences MeCP2-mediated gene repression. Proc Natl Acad Sci U S A. 2016 12 27; 113(52):15114-15119. PMID: 27965390.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  17. Ataman B, Boulting GL, Harmin DA, Yang MG, Baker-Salisbury M, Yap EL, Malik AN, Mei K, Rubin AA, Spiegel I, Durresi E, Sharma N, Hu LS, Pletikos M, Griffith EC, Partlow JN, Stevens CR, Adli M, Chahrour M, Sestan N, Walsh CA, Berezovskii VK, Livingstone MS, Greenberg ME. Evolution of Osteocrin as an activity-regulated factor in the primate brain. Nature. 2016 11 10; 539(7628):242-247. PMID: 27830782.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  18. O'Neill AK, Kindberg AA, Niethamer TK, Larson AR, Ho HH, Greenberg ME, Bush JO. Unidirectional Eph/ephrin signaling creates a cortical actomyosin differential to drive cell segregation. J Cell Biol. 2016 Oct 24; 215(2):217-229. PMID: 27810913.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  19. Hrvatin S, Nagy MA, Greenberg ME. Catching the Brain in the Act. Cell. 2016 06 16; 165(7):1570-1571. PMID: 27315474.
    Citations:    Fields:    Translation:AnimalsCells
  20. Mardinly AR, Spiegel I, Patrizi A, Centofante E, Bazinet JE, Tzeng CP, Mandel-Brehm C, Harmin DA, Adesnik H, Fagiolini M, Greenberg ME. Sensory experience regulates cortical inhibition by inducing IGF1 in VIP neurons. Nature. 2016 Mar 17; 531(7594):371-5. PMID: 26958833; PMCID: PMC4823817.
    Citations: 23     Fields:    Translation:AnimalsCells
  21. Loebrich S, Rathje M, Hager E, Ataman B, Harmin DA, Greenberg ME, Nedivi E. Genomic mapping and cellular expression of human CPG2 transcripts in the SYNE1 gene. Mol Cell Neurosci. 2016 Mar; 71:46-55. PMID: 26704904.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  22. Robichaux MA, Chenaux G, Ho HY, Soskis MJ, Greenberg ME, Henkemeyer M, Cowan CW. EphB1 and EphB2 intracellular domains regulate the formation of the corpus callosum and anterior commissure. Dev Neurobiol. 2016 Apr; 76(4):405-20. PMID: 26148571.
    Citations: 3     Fields:    Translation:AnimalsCells
  23. Sharma N, Gabel HW, Greenberg ME. A Shortcut to Activity-Dependent Transcription. Cell. 2015 Jun 18; 161(7):1496-8. PMID: 26091031.
    Citations:    
  24. Mandel-Brehm C, Salogiannis J, Dhamne SC, Rotenberg A, Greenberg ME. Seizure-like activity in a juvenile Angelman syndrome mouse model is attenuated by reducing Arc expression. Proc Natl Acad Sci U S A. 2015 Apr 21; 112(16):5129-34. PMID: 25848016; PMCID: PMC4413330.
    Citations: 17     Fields:    Translation:Animals
  25. Eisner A, Pazyra-Murphy MF, Durresi E, Zhou P, Zhao X, Chadwick EC, Xu PX, Hillman RT, Scott MP, Greenberg ME, Segal RA. The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis. Dev Cell. 2015 Apr 06; 33(1):22-35. PMID: 25816987; PMCID: PMC4418443.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  26. Andzelm MM, Cherry TJ, Harmin DA, Boeke AC, Lee C, Hemberg M, Pawlyk B, Malik AN, Flavell SW, Sandberg MA, Raviola E, Greenberg ME. MEF2D drives photoreceptor development through a genome-wide competition for tissue-specific enhancers. Neuron. 2015 Apr 08; 86(1):247-63. PMID: 25801704; PMCID: PMC4393375.
    Citations: 15     Fields:    Translation:AnimalsCells
  27. Gabel HW, Kinde B, Stroud H, Gilbert CS, Harmin DA, Kastan NR, Hemberg M, Ebert DH, Greenberg ME. Disruption of DNA-methylation-dependent long gene repression in Rett syndrome. Nature. 2015 Jun 04; 522(7554):89-93. PMID: 25762136; PMCID: PMC4480648.
    Citations: 119     Fields:    Translation:HumansAnimalsCells
  28. Kinde B, Gabel HW, Gilbert CS, Griffith EC, Greenberg ME. Reading the unique DNA methylation landscape of the brain: Non-CpG methylation, hydroxymethylation, and MeCP2. Proc Natl Acad Sci U S A. 2015 Jun 02; 112(22):6800-6. PMID: 25739960; PMCID: PMC4460470.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  29. Malik AN, Vierbuchen T, Hemberg M, Rubin AA, Ling E, Couch CH, Stroud H, Spiegel I, Farh KK, Harmin DA, Greenberg ME. Genome-wide identification and characterization of functional neuronal activity-dependent enhancers. Nat Neurosci. 2014 Oct; 17(10):1330-9. PMID: 25195102; PMCID: PMC4297619.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  30. Spiegel I, Mardinly AR, Gabel HW, Bazinet JE, Couch CH, Tzeng CP, Harmin DA, Greenberg ME. Npas4 regulates excitatory-inhibitory balance within neural circuits through cell-type-specific gene programs. Cell. 2014 May 22; 157(5):1216-29. PMID: 24855953; PMCID: PMC4089405.
    Citations: 72     Fields:    Translation:AnimalsCells
  31. Deng JV, Wan Y, Wang X, Cohen S, Wetsel WC, Greenberg ME, Kenny PJ, Calakos N, West AE. MeCP2 phosphorylation limits psychostimulant-induced behavioral and neuronal plasticity. J Neurosci. 2014 Mar 26; 34(13):4519-27. PMID: 24671997; PMCID: PMC3965780.
    Citations: 18     Fields:    Translation:AnimalsCells
  32. Robichaux MA, Chenaux G, Ho HY, Soskis MJ, Dravis C, Kwan KY, Šestan N, Greenberg ME, Henkemeyer M, Cowan CW. EphB receptor forward signaling regulates area-specific reciprocal thalamic and cortical axon pathfinding. Proc Natl Acad Sci U S A. 2014 Feb 11; 111(6):2188-93. PMID: 24453220; PMCID: PMC3926086.
    Citations: 13     Fields:    Translation:AnimalsCells
  33. Bloodgood BL, Sharma N, Browne HA, Trepman AZ, Greenberg ME. The activity-dependent transcription factor NPAS4 regulates domain-specific inhibition. Nature. 2013 Nov 07; 503(7474):121-5. PMID: 24201284; PMCID: PMC4169177.
    Citations: 69     Fields:    Translation:AnimalsCells
  34. Wrann CD, White JP, Salogiannnis J, Laznik-Bogoslavski D, Wu J, Ma D, Lin JD, Greenberg ME, Spiegelman BM. Exercise induces hippocampal BDNF through a PGC-1a/FNDC5 pathway. Cell Metab. 2013 Nov 05; 18(5):649-59. PMID: 24120943; PMCID: PMC3980968.
    Citations: 103     Fields:    Translation:HumansAnimalsCells
  35. Gabel HW, Greenberg ME. Genetics. The maturing brain methylome. Science. 2013 Aug 09; 341(6146):626-7. PMID: 23929975; PMCID: PMC4445635.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  36. Ebert DH, Gabel HW, Robinson ND, Kastan NR, Hu LS, Cohen S, Navarro AJ, Lyst MJ, Ekiert R, Bird AP, Greenberg ME. Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR. Nature. 2013 Jul 18; 499(7458):341-5. PMID: 23770587.
    Citations: 67     Fields:    Translation:HumansAnimalsCells
  37. Lyst MJ, Ekiert R, Ebert DH, Merusi C, Nowak J, Selfridge J, Guy J, Kastan NR, Robinson ND, de Lima Alves F, Rappsilber J, Greenberg ME, Bird A. Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor. Nat Neurosci. 2013 Jul; 16(7):898-902. PMID: 23770565.
    Citations: 90     Fields:    Translation:AnimalsCells
  38. Veeramah KR, Johnstone L, Karafet TM, Wolf D, Sprissler R, Salogiannis J, Barth-Maron A, Greenberg ME, Stuhlmann T, Weinert S, Jentsch TJ, Pazzi M, Restifo LL, Talwar D, Erickson RP, Hammer MF. Exome sequencing reveals new causal mutations in children with epileptic encephalopathies. Epilepsia. 2013 Jul; 54(7):1270-81. PMID: 23647072; PMCID: PMC3700577.
    Citations: 70     Fields:    Translation:HumansAnimalsCells
  39. Yu TW, Chahrour MH, Coulter ME, Jiralerspong S, Okamura-Ikeda K, Ataman B, Schmitz-Abe K, Harmin DA, Adli M, Malik AN, D'Gama AM, Lim ET, Sanders SJ, Mochida GH, Partlow JN, Sunu CM, Felie JM, Rodriguez J, Nasir RH, Ware J, Joseph RM, Hill RS, Kwan BY, Al-Saffar M, Mukaddes NM, Hashmi A, Balkhy S, Gascon GG, Hisama FM, LeClair E, Poduri A, Oner O, Al-Saad S, Al-Awadi SA, Bastaki L, Ben-Omran T, Teebi AS, Al-Gazali L, Eapen V, Stevens CR, Rappaport L, Gabriel SB, Markianos K, State MW, Greenberg ME, Taniguchi H, Braverman NE, Morrow EM, Walsh CA. Using whole-exome sequencing to identify inherited causes of autism. Neuron. 2013 Jan 23; 77(2):259-73. PMID: 23352163; PMCID: PMC3694430.
    Citations: 129     Fields:    Translation:HumansAnimalsCells
  40. Ebert DH, Greenberg ME. Activity-dependent neuronal signalling and autism spectrum disorder. Nature. 2013 Jan 17; 493(7432):327-37. PMID: 23325215; PMCID: PMC3576027.
    Citations: 169     Fields:    Translation:HumansCells
  41. Trauer JM, Bandaranayake D, Booy R, Chen MI, Cretikos M, Dowse GK, Dwyer DE, Greenberg ME, Huang QS, Khandaker G, Kok J, Laurie KL, Lee VJ, McVernon J, Walter S, Markey PG. Seroepidemiologic effects of influenza A(H1N1)pdm09 in Australia, New Zealand, and Singapore. Emerg Infect Dis. 2013 Jan; 19(1):92-101. PMID: 23260059; PMCID: PMC3557971.
    Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
  42. Yun J, Nagai T, Furukawa-Hibi Y, Kuroda K, Kaibuchi K, Greenberg ME, Yamada K. Neuronal Per Arnt Sim (PAS) domain protein 4 (NPAS4) regulates neurite outgrowth and phosphorylation of synapsin I. J Biol Chem. 2013 Jan 25; 288(4):2655-64. PMID: 23172225; PMCID: PMC3554932.
    Citations: 10     Fields:    Translation:AnimalsCells
  43. Soskis MJ, Ho HY, Bloodgood BL, Robichaux MA, Malik AN, Ataman B, Rubin AA, Zieg J, Zhang C, Shokat KM, Sharma N, Cowan CW, Greenberg ME. A chemical genetic approach reveals distinct EphB signaling mechanisms during brain development. Nat Neurosci. 2012 Dec; 15(12):1645-54. PMID: 23143520; PMCID: PMC3509236.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  44. Hemberg M, Gray JM, Cloonan N, Kuersten S, Grimmond S, Greenberg ME, Kreiman G. Integrated genome analysis suggests that most conserved non-coding sequences are regulatory factor binding sites. Nucleic Acids Res. 2012 Sep; 40(16):7858-69. PMID: 22684627; PMCID: PMC3439890.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  45. Schafer DP, Lehrman EK, Kautzman AG, Koyama R, Mardinly AR, Yamasaki R, Ransohoff RM, Greenberg ME, Barres BA, Stevens B. Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner. Neuron. 2012 May 24; 74(4):691-705. PMID: 22632727; PMCID: PMC3528177.
    Citations: 560     Fields:    Translation:AnimalsCells
  46. Chahrour MH, Yu TW, Lim ET, Ataman B, Coulter ME, Hill RS, Stevens CR, Schubert CR, Greenberg ME, Gabriel SB, Walsh CA. Whole-exome sequencing and homozygosity analysis implicate depolarization-regulated neuronal genes in autism. PLoS Genet. 2012; 8(4):e1002635. PMID: 22511880; PMCID: PMC3325173.
    Citations: 69     Fields:    Translation:HumansCells
  47. Ho HY, Susman MW, Bikoff JB, Ryu YK, Jonas AM, Hu L, Kuruvilla R, Greenberg ME. Wnt5a-Ror-Dishevelled signaling constitutes a core developmental pathway that controls tissue morphogenesis. Proc Natl Acad Sci U S A. 2012 Mar 13; 109(11):4044-51. PMID: 22343533; PMCID: PMC3306699.
    Citations: 74     Fields:    Translation:AnimalsCells
  48. Wills ZP, Mandel-Brehm C, Mardinly AR, McCord AE, Giger RJ, Greenberg ME. The nogo receptor family restricts synapse number in the developing hippocampus. Neuron. 2012 Feb 09; 73(3):466-81. PMID: 22325200; PMCID: PMC3532882.
    Citations: 49     Fields:    Translation:AnimalsCells
  49. Ross SE, McCord AE, Jung C, Atan D, Mok SI, Hemberg M, Kim TK, Salogiannis J, Hu L, Cohen S, Lin Y, Harrar D, McInnes RR, Greenberg ME. Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly. Neuron. 2012 Jan 26; 73(2):292-303. PMID: 22284184; PMCID: PMC3269007.
    Citations: 36     Fields:    Translation:AnimalsCells
  50. Goffin D, Allen M, Zhang L, Amorim M, Wang IT, Reyes AR, Mercado-Berton A, Ong C, Cohen S, Hu L, Blendy JA, Carlson GC, Siegel SJ, Greenberg ME, Zhou Z. Rett syndrome mutation MeCP2 T158A disrupts DNA binding, protein stability and ERP responses. Nat Neurosci. 2011 Nov 27; 15(2):274-83. PMID: 22119903; PMCID: PMC3267879.
    Citations: 66     Fields:    Translation:HumansAnimalsCells
  51. Soskis M, Salogiannis J, Greenberg M. EphrinBs send mixed messages. Nat Neurosci. 2011 Oct 26; 14(11):1356-8. PMID: 22030542.
    Citations: 1     Fields:    Translation:AnimalsCells
  52. Cohen S, Gabel HW, Hemberg M, Hutchinson AN, Sadacca LA, Ebert DH, Harmin DA, Greenberg RS, Verdine VK, Zhou Z, Wetsel WC, West AE, Greenberg ME. Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function. Neuron. 2011 Oct 06; 72(1):72-85. PMID: 21982370; PMCID: PMC3226708.
    Citations: 104     Fields:    Translation:AnimalsCells
  53. Odajima J, Wills ZP, Ndassa YM, Terunuma M, Kretschmannova K, Deeb TZ, Geng Y, Gawrzak S, Quadros IM, Newman J, Das M, Jecrois ME, Yu Q, Li N, Bienvenu F, Moss SJ, Greenberg ME, Marto JA, Sicinski P. Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation. Dev Cell. 2011 Oct 18; 21(4):655-68. PMID: 21944720; PMCID: PMC3199337.
    Citations: 49     Fields:    Translation:AnimalsCells
  54. West AE, Greenberg ME. Neuronal activity-regulated gene transcription in synapse development and cognitive function. Cold Spring Harb Perspect Biol. 2011 Jun 01; 3(6). PMID: 21555405; PMCID: PMC3098681.
    Citations: 157     Fields:    Translation:HumansCells
  55. Margolis SS, Salogiannis J, Lipton DM, Mandel-Brehm C, Wills ZP, Mardinly AR, Hu L, Greer PL, Bikoff JB, Ho HY, Soskis MJ, Sahin M, Greenberg ME. EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation. Cell. 2010 Oct 29; 143(3):442-55. PMID: 21029865; PMCID: PMC2967209.
    Citations: 89     Fields:    Translation:HumansAnimalsCells
  56. Kim TK, Hemberg M, Gray JM, Costa AM, Bear DM, Wu J, Harmin DA, Laptewicz M, Barbara-Haley K, Kuersten S, Markenscoff-Papadimitriou E, Kuhl D, Bito H, Worley PF, Kreiman G, Greenberg ME. Widespread transcription at neuronal activity-regulated enhancers. Nature. 2010 May 13; 465(7295):182-7. PMID: 20393465; PMCID: PMC3020079.
    Citations: 787     Fields:    Translation:AnimalsCells
  57. Ross SE, Mardinly AR, McCord AE, Zurawski J, Cohen S, Jung C, Hu L, Mok SI, Shah A, Savner EM, Tolias C, Corfas R, Chen S, Inquimbert P, Xu Y, McInnes RR, Rice FL, Corfas G, Ma Q, Woolf CJ, Greenberg ME. Loss of inhibitory interneurons in the dorsal spinal cord and elevated itch in Bhlhb5 mutant mice. Neuron. 2010 Mar 25; 65(6):886-98. PMID: 20346763; PMCID: PMC2856621.
    Citations: 129     Fields:    Translation:AnimalsCells
  58. Greer PL, Hanayama R, Bloodgood BL, Mardinly AR, Lipton DM, Flavell SW, Kim TK, Griffith EC, Waldon Z, Maehr R, Ploegh HL, Chowdhury S, Worley PF, Steen J, Greenberg ME. The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc. Cell. 2010 Mar 05; 140(5):704-16. PMID: 20211139; PMCID: PMC2843143.
    Citations: 200     Fields:    Translation:HumansAnimalsCells
  59. Cohen S, Greenberg ME. A bird's-eye view of MeCP2 binding. Mol Cell. 2010 Feb 26; 37(4):451-2. PMID: 20188662.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  60. Shi L, Butt B, Ip FC, Dai Y, Jiang L, Yung WH, Greenberg ME, Fu AK, Ip NY. Ephexin1 is required for structural maturation and neurotransmission at the neuromuscular junction. Neuron. 2010 Jan 28; 65(2):204-16. PMID: 20152127; PMCID: PMC3718047.
    Citations: 15     Fields:    Translation:AnimalsCells
  61. Greenberg ME, Xu B, Lu B, Hempstead BL. New insights in the biology of BDNF synthesis and release: implications in CNS function. J Neurosci. 2009 Oct 14; 29(41):12764-7. PMID: 19828787; PMCID: PMC3091387.
    Citations: 171     Fields:    Translation:AnimalsCells
  62. Bracaglia G, Conca B, Bergo A, Rusconi L, Zhou Z, Greenberg ME, Landsberger N, Soddu S, Kilstrup-Nielsen C. Methyl-CpG-binding protein 2 is phosphorylated by homeodomain-interacting protein kinase 2 and contributes to apoptosis. EMBO Rep. 2009 Dec; 10(12):1327-33. PMID: 19820693; PMCID: PMC2799202.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  63. Wood L, Gray NW, Zhou Z, Greenberg ME, Shepherd GM. Synaptic circuit abnormalities of motor-frontal layer 2/3 pyramidal neurons in an RNA interference model of methyl-CpG-binding protein 2 deficiency. J Neurosci. 2009 Oct 07; 29(40):12440-8. PMID: 19812320; PMCID: PMC2782478.
    Citations: 54     Fields:    Translation:AnimalsCells
  64. Greenberg ME, Smith JD, Sehayek E. Moderately decreased cholesterol absorption rates are associated with a large atheroprotective effect. Arterioscler Thromb Vasc Biol. 2009 Nov; 29(11):1745-50. PMID: 19661480; PMCID: PMC2766672.
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  66. Pazyra-Murphy MF, Hans A, Courchesne SL, Karch C, Cosker KE, Heerssen HM, Watson FL, Kim T, Greenberg ME, Segal RA. A retrograde neuronal survival response: target-derived neurotrophins regulate MEF2D and bcl-w. J Neurosci. 2009 May 20; 29(20):6700-9. PMID: 19458239; PMCID: PMC2709981.
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  67. Fiore R, Khudayberdiev S, Christensen M, Siegel G, Flavell SW, Kim TK, Greenberg ME, Schratt G. Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels. EMBO J. 2009 Mar 18; 28(6):697-710. PMID: 19197241; PMCID: PMC2647767.
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  69. Flavell SW, Kim TK, Gray JM, Harmin DA, Hemberg M, Hong EJ, Markenscoff-Papadimitriou E, Bear DM, Greenberg ME. Genome-wide analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity-dependent polyadenylation site selection. Neuron. 2008 Dec 26; 60(6):1022-38. PMID: 19109909; PMCID: PMC2630178.
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  70. Hong EJ, McCord AE, Greenberg ME. A biological function for the neuronal activity-dependent component of Bdnf transcription in the development of cortical inhibition. Neuron. 2008 Nov 26; 60(4):610-24. PMID: 19038219; PMCID: PMC2873221.
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  71. Greenberg MJ, Watt JD, Jones M, Kazmierczak K, Szczesna-Cordary D, Moore JR. Regulatory light chain mutations associated with cardiomyopathy affect myosin mechanics and kinetics. J Mol Cell Cardiol. 2009 Jan; 46(1):108-15. PMID: 18929571; PMCID: PMC2675789.
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  72. Greer PL, Greenberg ME. From synapse to nucleus: calcium-dependent gene transcription in the control of synapse development and function. Neuron. 2008 Sep 25; 59(6):846-60. PMID: 18817726.
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  73. Lin Y, Bloodgood BL, Hauser JL, Lapan AD, Koon AC, Kim TK, Hu LS, Malik AN, Greenberg ME. Activity-dependent regulation of inhibitory synapse development by Npas4. Nature. 2008 Oct 30; 455(7217):1198-204. PMID: 18815592; PMCID: PMC2637532.
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  74. Zieg J, Greer PL, Greenberg ME. SnapShot: Ca(2+)-dependent transcription in neurons. Cell. 2008 Sep 19; 134(6):1080-1080.e2. PMID: 18805099.
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  75. Morrow EM, Yoo SY, Flavell SW, Kim TK, Lin Y, Hill RS, Mukaddes NM, Balkhy S, Gascon G, Hashmi A, Al-Saad S, Ware J, Joseph RM, Greenblatt R, Gleason D, Ertelt JA, Apse KA, Bodell A, Partlow JN, Barry B, Yao H, Markianos K, Ferland RJ, Greenberg ME, Walsh CA. Identifying autism loci and genes by tracing recent shared ancestry. Science. 2008 Jul 11; 321(5886):218-23. PMID: 18621663; PMCID: PMC2586171.
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  76. Cohen S, Zhou Z, Greenberg ME. Medicine. Activating a repressor. Science. 2008 May 30; 320(5880):1172-3. PMID: 18511680; PMCID: PMC2857976.
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  77. Ma YC, Song MR, Park JP, Henry Ho HY, Hu L, Kurtev MV, Zieg J, Ma Q, Pfaff SL, Greenberg ME. Regulation of motor neuron specification by phosphorylation of neurogenin 2. Neuron. 2008 Apr 10; 58(1):65-77. PMID: 18400164; PMCID: PMC2587148.
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  78. Kim DS, Ross SE, Trimarchi JM, Aach J, Greenberg ME, Cepko CL. Identification of molecular markers of bipolar cells in the murine retina. J Comp Neurol. 2008 Apr 10; 507(5):1795-810. PMID: 18260140; PMCID: PMC2665264.
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  79. Singh KK, Park KJ, Hong EJ, Kramer BM, Greenberg ME, Kaplan DR, Miller FD. Developmental axon pruning mediated by BDNF-p75NTR-dependent axon degeneration. Nat Neurosci. 2008 Jun; 11(6):649-58. PMID: 18382462.
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  81. Flavell SW, Greenberg ME. Signaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous system. Annu Rev Neurosci. 2008; 31:563-90. PMID: 18558867; PMCID: PMC2728073.
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  83. Ogier M, Wang H, Hong E, Wang Q, Greenberg ME, Katz DM. Brain-derived neurotrophic factor expression and respiratory function improve after ampakine treatment in a mouse model of Rett syndrome. J Neurosci. 2007 Oct 03; 27(40):10912-7. PMID: 17913925.
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  84. Zhou P, Porcionatto M, Pilapil M, Chen Y, Choi Y, Tolias KF, Bikoff JB, Hong EJ, Greenberg ME, Segal RA. Polarized signaling endosomes coordinate BDNF-induced chemotaxis of cerebellar precursors. Neuron. 2007 Jul 05; 55(1):53-68. PMID: 17610817; PMCID: PMC2661852.
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  85. Tolias KF, Bikoff JB, Kane CG, Tolias CS, Hu L, Greenberg ME. The Rac1 guanine nucleotide exchange factor Tiam1 mediates EphB receptor-dependent dendritic spine development. Proc Natl Acad Sci U S A. 2007 Apr 24; 104(17):7265-70. PMID: 17440041; PMCID: PMC1855368.
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  86. Greenberg ME, Bender TP. Identification of newly transcribed RNA. Curr Protoc Mol Biol. 2007 Apr; Chapter 4:Unit 4.10. PMID: 18265405.
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  87. Paradis S, Harrar DB, Lin Y, Koon AC, Hauser JL, Griffith EC, Zhu L, Brass LF, Chen C, Greenberg ME. An RNAi-based approach identifies molecules required for glutamatergic and GABAergic synapse development. Neuron. 2007 Jan 18; 53(2):217-32. PMID: 17224404; PMCID: PMC1950560.
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  88. Fu WY, Chen Y, Sahin M, Zhao XS, Shi L, Bikoff JB, Lai KO, Yung WH, Fu AK, Greenberg ME, Ip NY. Cdk5 regulates EphA4-mediated dendritic spine retraction through an ephexin1-dependent mechanism. Nat Neurosci. 2007 Jan; 10(1):67-76. PMID: 17143272.
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  89. Greenberg ME, Sun M, Zhang R, Febbraio M, Silverstein R, Hazen SL. Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells. J Exp Med. 2006 Nov 27; 203(12):2613-25. PMID: 17101731; PMCID: PMC2118161.
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  91. Marinescu VD, Kohane IS, Kim TK, Harmin DA, Greenberg ME, Riva A. START: an automated tool for serial analysis of chromatin occupancy data. Bioinformatics. 2006 Apr 15; 22(8):999-1001. PMID: 16500934.
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  92. Flavell SW, Cowan CW, Kim TK, Greer PL, Lin Y, Paradis S, Griffith EC, Hu LS, Chen C, Greenberg ME. Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number. Science. 2006 Feb 17; 311(5763):1008-12. PMID: 16484497.
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  97. Egea J, Nissen UV, Dufour A, Sahin M, Greer P, Kullander K, Mrsic-Flogel TD, Greenberg ME, Kiehn O, Vanderhaeghen P, Klein R. Regulation of EphA 4 kinase activity is required for a subset of axon guidance decisions suggesting a key role for receptor clustering in Eph function. Neuron. 2005 Aug 18; 47(4):515-28. PMID: 16102535.
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  98. Cowan CW, Shao YR, Sahin M, Shamah SM, Lin MZ, Greer PL, Gao S, Griffith EC, Brugge JS, Greenberg ME. Vav family GEFs link activated Ephs to endocytosis and axon guidance. Neuron. 2005 Apr 21; 46(2):205-17. PMID: 15848800.
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