Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Joel Naom Hirschhorn, M.D., Ph.D.

Title
Institution
Department
Address
Phone

Mentoring
Available: 09/01/24, Expires: 09/01/25

Our lab uses a variety of approaches, including computational analysis, clinical research, and basic wet-lab research, to understand the genetic and biological basis of disorders related to endocrinology. Specific projects include (1) computational and genomic analysis to identify causal genes, mechanisms and biological pathways by which noncoding variants affect obesity, short stature, diabetic kidney disease, or Graves Disease; (2) analysis of metabolomic and genetic data to understand the causal connections between diet, metabolite levels, and disease outcomes; (3) functional genomics to identify causal genes and delineate mechanisms by which they regulate skeletal growth or obesity; (4) helping to decipher the genetic basis of hypermobile Ehlers Danlos syndrome; (5) basic mouse and cell culture research to discover the mechanisms by which topiramate suppresses appetite


Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DK132299 (HIRSCHHORN, JOEL N) Aug 1, 2022 - May 31, 2027
    NIH
    A functional genomics pipeline for genetic discovery in diabetic kidney disease
    Role: Principal Investigator
  2. R01DK125273 (HIRSCHHORN, JOEL N) Aug 12, 2020 - Apr 30, 2025
    NIH
    Metabolomics from a Controlled Feeding Study and Large Cohorts to Identify Diet-Associated Biomarkers, Augmented by Genetics to Infer Causality for Cardiometabolic Outcomes
    Role: Principal Investigator
  3. R01HD089521 (CHAN, YEE-MING) Sep 10, 2016 - May 31, 2021
    NIH
    Exome Sequencing in Disorders of Sex Development: Impact on Patients and Families
    Role: Principal Investigator
  4. R01DK105154 (HIRSCHHORN, JOEL N) Dec 23, 2015 - Nov 30, 2020
    NIH
    Integrative genomic, epigenetic and functional studies in diabetic kidney disease
    Role: Co-Principal Investigator
  5. R01DK081923 (HIRSCHHORN, JOEL N) May 15, 2009 - Apr 30, 2014
    NIH
    Genome-Wide Association Studies of Diabetic Nephropathy
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Updating...
This operation might take several minutes to complete. Please do not close your browser.
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Hirschhorn's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (873)
Explore
_
Co-Authors (226)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Physical Neighbors
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.