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Barbara Burleigh, Ph.D.

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Yale University School of MedicineAssociate Research Scientist1999Molecular Parasitology
Yale University School of MedicinePost-doctoral fellow1997Host-pathogen interactions; parasitology; cell biology.
University of Western OntarioPh.D1992Molecular and Cellular Parasitology
University of Western OntarioB.Sc.1986Microbiology

Barbara Burleigh holds a joint appointment as Professor in the Departments of Immunology and Infectious Diseases as well as the Department of Molecular Metabolism. After obtaining her Ph.D. in molecular and cellular parasitology from the University of Western Ontario, Dr. Burleigh trained as a postdoctoral fellow at Yale School of Medicine, where she gained expertise in the cell biology of host-pathogen interactions.

As an obligate intracellular parasite that lives in the cytoplasm of its mammalian host cell, the Chagas' disease parasite, Trypanosoma cruzi, forges functional connections with its host cell in order to survive. In other words, T. cruzi becomes part of an integrated biological system: the 'host-parasite network'. Research in my laboratory seeks to understand how T. cruzi exploits host functions to establish intracellular infection in mammalian cells. Our general approach has been to view this relationship through the lens of the mammalian host cell, where our studies have probed mechanisms of host cell entry by T. cruzi, identified cellular pathways that support intracellular replication of the parasite and have determined the impact of infection on host gene expression and physiology. In these efforts, we have exploited a combination of genomic, transcriptomic and cell biological approaches. With the advancement of genome-scale technologies, we are now in a position to integrate parasite and host gene expression data with host functional genomic data to expose biological networks representing metabolic cross talk between host and parasite. Our recent functional genomic studies, for example, indicate critical points in host metabolic networks to which T. cruzi parasites couple their metabolic needs. The role of host cellular metabolism in supporting T. cruzi infection is a new area of investigation in the Chagas' disease field that we are excited to develop with key collaborators. These studies will provide essential insights into the fundamental basis for T. cruzi parasitism, which has the potential to be leveraged in the development of novel therapeutics for Chagas' disease.

Current projects in the lab include the study of host fatty acid metabolism and its role in fueling T. cruzi replication in myoblasts and iPSC-derived human cardiomyocytes; the role of host cytoskeletal dynamics in supporting intracellular parasite growth; and the use of transcriptomic signatures (RNA-Seq) to predict metabolic and functional adaptation in T. cruzi developmental stages and across recent parasite isolates.

The Role of Endosomal Regulators and ER-Mediated Phagocytosis in Trypanosoma cruzi Invasion and Vacuole Maturation
Summer, 05/23/05 - 07/31/06

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21AI166974 (BURLEIGH, BARBARA A) Sep 27, 2021 - Aug 31, 2023
    Exploring the potential to improve azole efficacy against Trypanosoma cruzi by targeting glutamine metabolism
    Role: Principal Investigator
  2. R21AI146815 (BURLEIGH, BARBARA A) Jun 10, 2019 - May 31, 2021
    Exploring metabolic resistance to small molecule inhibitors in Trypanosoma cruzi
    Role: Principal Investigator
  3. R21AI135520 (BURLEIGH, BARBARA A) Dec 4, 2017 - Nov 30, 2020
    Characterization of a novel interaction between intracellular T. cruzi amastigotes and host mitochondria
    Role: Principal Investigator
  4. R01AI114622 (BURLEIGH, BARBARA A) May 1, 2015 - Apr 30, 2021
    Role of host fatty acid metabolism in Trypanosoma cruzi amastigote growth
    Role: Principal Investigator
  5. R21AI113121 (BURLEIGH, BARBARA A) Jan 1, 2015 - Jun 30, 2017
    Functional characterization of Trypanosoma cruzi-host cytoskeletal interactions
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Won MM, Krüger T, Engstler M, Burleigh BA. The Intracellular Amastigote of Trypanosoma cruzi Maintains an Actively Beating Flagellum. mBio. 2023 Feb 22; e0355622. PMID: 36840555.
    Citations: 1     Fields:    
  2. Won MM, Baublis A, Burleigh BA. Proximity-dependent biotinylation and identification of flagellar proteins in Trypanosoma cruzi. bioRxiv. 2023 Feb 22. PMID: 36824716; PMCID: PMC9949143.
  3. Dumoulin PC, Vollrath J, Won MM, Wang JX, Burleigh BA. Endogenous Sterol Synthesis Is Dispensable for Trypanosoma cruzi Epimastigote Growth but Not Stress Tolerance. Front Microbiol. 2022; 13:937910. PMID: 35783434; PMCID: PMC9248972.
    Citations: 1     
  4. Calzada JE, Samudio F, de Juncá C, Pineda V, Burleigh BA, Saldaña A. Genetic Diversity of Trypanosoma cruzi in Panama Inferred by Multi-locus Sequence Typing of Mitochondrial Genes. Microorganisms. 2022 Jan 26; 10(2). PMID: 35208746; PMCID: PMC8879757.
    Citations: 1     
  5. Burleigh B, McConville M. Editorial overview: The diverse and secret lives of intracellular protist pathogens. Curr Opin Microbiol. 2021 12; 64:166-169. PMID: 34756536.
    Citations:    Fields:    Translation:Animals
  6. Dumoulin PC, Burleigh BA. Metabolic flexibility in Trypanosoma cruzi amastigotes: implications for persistence and drug sensitivity. Curr Opin Microbiol. 2021 10; 63:244-249. PMID: 34455305; PMCID: PMC8463458.
    Citations: 1     Fields:    Translation:Animals
  7. Ferreira ER, Bonfim-Melo A, Burleigh BA, Costales JA, Tyler KM, Mortara RA. Parasite-Mediated Remodeling of the Host Microfilament Cytoskeleton Enables Rapid Egress of Trypanosoma cruzi following Membrane Rupture. mBio. 2021 06 29; 12(3):e0098821. PMID: 34154418.
    Citations: 1     Fields:    Translation:AnimalsCells
  8. Talavera-López C, Messenger LA, Lewis MD, Yeo M, Reis-Cunha JL, Matos GM, Bartholomeu DC, Calzada JE, Saldaña A, Ramírez JD, Guhl F, Ocaña-Mayorga S, Costales JA, Gorchakov R, Jones K, Nolan MS, Teixeira SMR, Carrasco HJ, Bottazzi ME, Hotez PJ, Murray KO, Grijalva MJ, Burleigh B, Grisard EC, Miles MA, Andersson B. Repeat-Driven Generation of Antigenic Diversity in a Major Human Pathogen, Trypanosoma cruzi. Front Cell Infect Microbiol. 2021; 11:614665. PMID: 33747978; PMCID: PMC7966520.
    Citations: 15     Fields:    Translation:Animals
  9. Dumoulin PC, Vollrath J, Tomko SS, Wang JX, Burleigh B. Glutamine metabolism modulates azole susceptibility in Trypanosoma cruzi amastigotes. Elife. 2020 12 01; 9. PMID: 33258448.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  10. Oliveira AER, Pereira MCA, Belew AT, Ferreira LRP, Pereira LMN, Neves EGA, Nunes MDCP, Burleigh BA, Dutra WO, El-Sayed NM, Gazzinelli RT, Teixeira SMR. Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi strains unveil a role for fibroblasts in neutrophil recruitment and activation. PLoS Pathog. 2020 08; 16(8):e1008781. PMID: 32810179.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  11. Clements RL, Streva V, Dumoulin P, Huang W, Owens E, Raj DK, Burleigh B, Llinás M, Winzeler EA, Zhang Q, Dvorin JD. A Novel Antiparasitic Compound Kills Ring-Stage Plasmodium falciparum and Retains Activity Against Artemisinin-Resistant Parasites. J Infect Dis. 2020 03 02; 221(6):956-962. PMID: 31616928; PMCID: PMC7050989.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  12. Dumoulin PC, Burleigh BA. Methods for the Investigation of Trypanosoma cruzi Amastigote Proliferation in Mammalian Host Cells. Methods Mol Biol. 2020; 2116:535-554. PMID: 32221941.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  13. Dumoulin PC, Burleigh BA. Stress-Induced Proliferation and Cell Cycle Plasticity of Intracellular Trypanosoma cruzi Amastigotes. mBio. 2018 07 10; 9(4). PMID: 29991586.
    Citations: 21     Fields:    Translation:AnimalsCells
  14. Gazos-Lopes F, Martin JL, Dumoulin PC, Burleigh BA. Host triacylglycerols shape the lipidome of intracellular trypanosomes and modulate their growth. PLoS Pathog. 2017 12; 13(12):e1006800. PMID: 29281741; PMCID: PMC5760102.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  15. Belew AT, Junqueira C, Rodrigues-Luiz GF, Valente BM, Oliveira AER, Polidoro RB, Zuccherato LW, Bartholomeu DC, Schenkman S, Gazzinelli RT, Burleigh BA, El-Sayed NM, Teixeira SMR. Comparative transcriptome profiling of virulent and non-virulent Trypanosoma cruzi underlines the role of surface proteins during infection. PLoS Pathog. 2017 12; 13(12):e1006767. PMID: 29240831; PMCID: PMC5746284.
    Citations: 28     Fields:    Translation:HumansAnimals
  16. Lentini G, Dos Santos Pacheco N, Burleigh BA. Targeting host mitochondria: A role for the Trypanosoma cruzi amastigote flagellum. Cell Microbiol. 2018 02; 20(2). PMID: 29119655; PMCID: PMC5764780.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  17. Shah-Simpson S, Lentini G, Dumoulin PC, Burleigh BA. Modulation of host central carbon metabolism and in situ glucose uptake by intracellular Trypanosoma cruzi amastigotes. PLoS Pathog. 2017 Nov; 13(11):e1006747. PMID: 29176805; PMCID: PMC5720825.
    Citations: 25     Fields:    Translation:HumansAnimals
  18. Shah-Simpson S, Pereira CF, Dumoulin PC, Caradonna KL, Burleigh BA. Bioenergetic profiling of Trypanosoma cruzi life stages using Seahorse extracellular flux technology. Mol Biochem Parasitol. 2016 08; 208(2):91-5. PMID: 27392747.
    Citations: 13     Fields:    Translation:AnimalsCells
  19. Burleigh BA, Boothroyd JC. Editorial overview: Host-microbe interactions: parasites: How eukaryotic parasites meet the challenges of life in a host. Curr Opin Microbiol. 2016 08; 32:viii-xi. PMID: 27372032.
    Citations:    Fields:    Translation:AnimalsCells
  20. Li Y, Shah-Simpson S, Okrah K, Belew AT, Choi J, Caradonna KL, Padmanabhan P, Ndegwa DM, Temanni MR, Corrada Bravo H, El-Sayed NM, Burleigh BA. Transcriptome Remodeling in Trypanosoma cruzi and Human Cells during Intracellular Infection. PLoS Pathog. 2016 Apr; 12(4):e1005511. PMID: 27046031; PMCID: PMC4821583.
    Citations: 80     Fields:    Translation:HumansAnimalsCells
  21. Dotiwala F, Mulik S, Polidoro RB, Ansara JA, Burleigh BA, Walch M, Gazzinelli RT, Lieberman J. Killer lymphocytes use granulysin, perforin and granzymes to kill intracellular parasites. Nat Med. 2016 Feb; 22(2):210-6. PMID: 26752517.
    Citations: 83     Fields:    Translation:HumansAnimalsCells
  22. Costales JA, Kotton CN, Zurita-Leal AC, Garcia-Perez J, Llewellyn MS, Messenger LA, Bhattacharyya T, Burleigh BA. Chagas disease reactivation in a heart transplant patient infected by domestic Trypanosoma cruzi discrete typing unit I (TcIDOM). Parasit Vectors. 2015 Aug 25; 8:435. PMID: 26303927.
    Citations: 6     Fields:    Translation:HumansAnimals
  23. Padmanabhan PK, Polidoro RB, Barteneva NS, Gazzinelli RT, Burleigh BA. Transient transfection and expression of foreign and endogenous genes in the intracellular stages of Trypanosoma cruzi. Mol Biochem Parasitol. 2014 Dec; 198(2):100-3. PMID: 25712770.
    Citations: 3     Fields:    Translation:AnimalsCells
  24. Liu L, Xu YX, Caradonna KL, Kruzel EK, Burleigh BA, Bangs JD, Hirschberg CB. Inhibition of nucleotide sugar transport in Trypanosoma brucei alters surface glycosylation. J Biol Chem. 2013 Apr 12; 288(15):10599-615. PMID: 23443657.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  25. Caradonna KL, Engel JC, Jacobi D, Lee CH, Burleigh BA. Host metabolism regulates intracellular growth of Trypanosoma cruzi. Cell Host Microbe. 2013 Jan 16; 13(1):108-17. PMID: 23332160.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  26. Zhao X, Kumar P, Shah-Simpson S, Caradonna KL, Galjart N, Teygong C, Blader I, Wittmann T, Burleigh BA. Host microtubule plus-end binding protein CLASP1 influences sequential steps in the Trypanosoma cruzi infection process. Cell Microbiol. 2013 Apr; 15(4):571-84. PMID: 23107073.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  27. Nagajyothi F, Machado FS, Burleigh BA, Jelicks LA, Scherer PE, Mukherjee S, Lisanti MP, Weiss LM, Garg NJ, Tanowitz HB. Mechanisms of Trypanosoma cruzi persistence in Chagas disease. Cell Microbiol. 2012 May; 14(5):634-43. PMID: 22309180.
    Citations: 69     Fields:    Translation:HumansAnimals
  28. Mott GA, Costales JA, Burleigh BA. A soluble factor from Trypanosoma cruzi inhibits transforming growth factor-ß-induced MAP kinase activation and gene expression in dermal fibroblasts. PLoS One. 2011; 6(9):e23482. PMID: 21931601.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  29. Virreira Winter S, Niedelman W, Jensen KD, Rosowski EE, Julien L, Spooner E, Caradonna K, Burleigh BA, Saeij JP, Ploegh HL, Frickel EM. Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it. PLoS One. 2011; 6(9):e24434. PMID: 21931713; PMCID: PMC3169597.
    Citations: 74     Fields:    Translation:HumansAnimalsCells
  30. Andriani G, Chessler AD, Courtemanche G, Burleigh BA, Rodriguez A. Activity in vivo of anti-Trypanosoma cruzi compounds selected from a high throughput screening. PLoS Negl Trop Dis. 2011 Aug; 5(8):e1298. PMID: 21912715.
    Citations: 33     Fields:    Translation:Animals
  31. Chessler AD, Caradonna KL, Da'dara A, Burleigh BA. Type I interferons increase host susceptibility to Trypanosoma cruzi infection. Infect Immun. 2011 May; 79(5):2112-9. PMID: 21402764.
    Citations: 18     Fields:    Translation:Animals
  32. Caradonna KL, Burleigh BA. Mechanisms of host cell invasion by Trypanosoma cruzi. Adv Parasitol. 2011; 76:33-61. PMID: 21884886.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  33. Costales JA, Daily JP, Burleigh BA. Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling. BMC Genomics. 2009 May 29; 10:252. PMID: 19480704.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  34. Chessler AD, Unnikrishnan M, Bei AK, Daily JP, Burleigh BA. Trypanosoma cruzi triggers an early type I IFN response in vivo at the site of intradermal infection. J Immunol. 2009 Feb 15; 182(4):2288-96. PMID: 19201883.
    Citations: 22     Fields:    Translation:AnimalsCells
  35. Mott A, Lenormand G, Costales J, Fredberg JJ, Burleigh BA. Modulation of host cell mechanics by Trypanosoma cruzi. J Cell Physiol. 2009 Feb; 218(2):315-22. PMID: 18853412; PMCID: PMC2592505.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  36. Samanovic M, Molina-Portela MP, Chessler AD, Burleigh BA, Raper J. Trypanosome lytic factor, an antimicrobial high-density lipoprotein, ameliorates Leishmania infection. PLoS Pathog. 2009 Jan; 5(1):e1000276. PMID: 19165337.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  37. Kawashita SY, da Silva CV, Mortara RA, Burleigh BA, Briones MR. Homology, paralogy and function of DGF-1, a highly dispersed Trypanosoma cruzi specific gene family and its implications for information entropy of its encoded proteins. Mol Biochem Parasitol. 2009 May; 165(1):19-31. PMID: 19393159.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  38. Chessler AD, Ferreira LR, Chang TH, Fitzgerald KA, Burleigh BA. A novel IFN regulatory factor 3-dependent pathway activated by trypanosomes triggers IFN-beta in macrophages and fibroblasts. J Immunol. 2008 Dec 01; 181(11):7917-24. PMID: 19017982; PMCID: PMC2597000.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  39. Burleigh BA, Sinai AP. Molecular mechanisms of parasite invasion. Preface. Subcell Biochem. 2008; 47:xix-xx. PMID: 18512337.
    Citations:    Fields:    Translation:HumansAnimals
  40. Burleigh B, Soldati-Favre D. Dedication. Subcell Biochem. 2008; 47:vii-viii. PMID: 18581654.
  41. Mott GA, Burleigh BA. The role of host cell lysosomes in Trypanosoma cruzi invasion. Subcell Biochem. 2008; 47:165-73. PMID: 18512350.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  42. Fisch S, Gray S, Heymans S, Haldar SM, Wang B, Pfister O, Cui L, Kumar A, Lin Z, Sen-Banerjee S, Das H, Petersen CA, Mende U, Burleigh BA, Zhu Y, Pinto YM, Pinto Y, Liao R, Jain MK. Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy. Proc Natl Acad Sci U S A. 2007 Apr 24; 104(17):7074-9. PMID: 17438289; PMCID: PMC1855421.
    Citations: 92     Fields:    Translation:HumansAnimalsCells
  43. Petersen CA, Krumholz KA, Carmen J, Sinai AP, Burleigh BA. Trypanosoma cruzi infection and nuclear factor kappa B activation prevent apoptosis in cardiac cells. Infect Immun. 2006 Mar; 74(3):1580-7. PMID: 16495529; PMCID: PMC1418648.
    Citations: 22     Fields:    Translation:AnimalsCells
  44. Petersen CA, Krumholz KA, Burleigh BA. Toll-like receptor 2 regulates interleukin-1beta-dependent cardiomyocyte hypertrophy triggered by Trypanosoma cruzi. Infect Immun. 2005 Oct; 73(10):6974-80. PMID: 16177377; PMCID: PMC1230932.
    Citations: 24     Fields:    Translation:AnimalsCells
  45. Burleigh BA. Host cell signaling and Trypanosoma cruzi invasion: do all roads lead to lysosomes? Sci STKE. 2005 Jul 19; 2005(293):pe36. PMID: 16030288.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  46. Unnikrishnan M, Burleigh BA. Inhibition of host connective tissue growth factor expression: a novel Trypanosoma cruzi-mediated response. FASEB J. 2004 Nov; 18(14):1625-35. PMID: 15522908.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  47. Woolsey AM, Burleigh BA. Host cell actin polymerization is required for cellular retention of Trypanosoma cruzi and early association with endosomal/lysosomal compartments. Cell Microbiol. 2004 Sep; 6(9):829-38. PMID: 15272864.
    Citations: 32     Fields:    Translation:AnimalsCells
  48. Burleigh BA. Probing Trypanosoma cruzi biology with DNA microarrays. Parasitology. 2004; 128 Suppl 1:S3-10. PMID: 16454896.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  49. Petersen CA, Burleigh BA. Role for interleukin-1 beta in Trypanosoma cruzi-induced cardiomyocyte hypertrophy. Infect Immun. 2003 Aug; 71(8):4441-7. PMID: 12874323.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  50. Woolsey AM, Sunwoo L, Petersen CA, Brachmann SM, Cantley LC, Burleigh BA. Novel PI 3-kinase-dependent mechanisms of trypanosome invasion and vacuole maturation. J Cell Sci. 2003 Sep 01; 116(Pt 17):3611-22. PMID: 12876217.
    Citations: 68     Fields:    Translation:AnimalsCells
  51. Burleigh BA, Woolsey AM. Cell signalling and Trypanosoma cruzi invasion. Cell Microbiol. 2002 Nov; 4(11):701-11. PMID: 12427093.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  52. Vaena de Avalos S, Blader IJ, Fisher M, Boothroyd JC, Burleigh BA. Immediate/early response to Trypanosoma cruzi infection involves minimal modulation of host cell transcription. J Biol Chem. 2002 Jan 04; 277(1):639-44. PMID: 11668183.
    Citations: 52     Fields:    Translation:HumansAnimalsCells
  53. Kima PE, Burleigh B, Andrews NW. Surface-targeted lysosomal membrane glycoprotein-1 (Lamp-1) enhances lysosome exocytosis and cell invasion by Trypanosoma cruzi. Cell Microbiol. 2000 Dec; 2(6):477-86. PMID: 11207602.
    Citations: 22     Fields:    Translation:AnimalsCells
  54. Caler EV, Morty RE, Burleigh BA, Andrews NW. Dual role of signaling pathways leading to Ca(2+) and cyclic AMP elevation in host cell invasion by Trypanosoma cruzi. Infect Immun. 2000 Dec; 68(12):6602-10. PMID: 11083771.
    Citations: 33     Fields:    Translation:AnimalsCells
  55. Caler EV, Vaena de Avalos S, Haynes PA, Andrews NW, Burleigh BA. Oligopeptidase B-dependent signaling mediates host cell invasion by Trypanosoma cruzi. EMBO J. 1998 Sep 01; 17(17):4975-86. PMID: 9724634; PMCID: PMC1170826.
    Citations: 68     Fields:    Translation:HumansAnimalsCells
  56. Burleigh BA, Andrews NW. Signaling and host cell invasion by Trypanosoma cruzi. Curr Opin Microbiol. 1998 Aug; 1(4):461-5. PMID: 10066513.
    Citations: 33     Fields:    Translation:AnimalsCells
  57. Burleigh BA, Caler EV, Webster P, Andrews NW. A cytosolic serine endopeptidase from Trypanosoma cruzi is required for the generation of Ca2+ signaling in mammalian cells. J Cell Biol. 1997 Feb 10; 136(3):609-20. PMID: 9024691; PMCID: PMC2134300.
    Citations: 46     Fields:    Translation:AnimalsCells
  58. Gardiner PR, Nene V, Barry MM, Thatthi R, Burleigh B, Clarke MW. Characterization of a small variable surface glycoprotein from Trypanosoma vivax. Mol Biochem Parasitol. 1996 Nov 12; 82(1):1-11. PMID: 8943146.
    Citations: 6     Fields:    Translation:AnimalsCells
  59. Burleigh BA, Andrews NW. A 120-kDa alkaline peptidase from Trypanosoma cruzi is involved in the generation of a novel Ca(2+)-signaling factor for mammalian cells. J Biol Chem. 1995 Mar 10; 270(10):5172-80. PMID: 7890627.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  60. Burleigh BA, Andrews NW. The mechanisms of Trypanosoma cruzi invasion of mammalian cells. Annu Rev Microbiol. 1995; 49:175-200. PMID: 8561458.
    Citations: 55     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.