Harvard Catalyst Profiles

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George L. Mutter, M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01CA100833 (MUTTER, GEORGE L) Jun 1, 2004 - Apr 30, 2010
    Hormonal modulation of latent endometrial precancers
    Role: Principal Investigator
  2. R01CA092301 (MUTTER, GEORGE L) Aug 1, 2002 - Jul 31, 2008
    Biomarkers and Chemoprevention of Endometrial Cancer
    Role: Principal Investigator
  3. R29CA049859 (MUTTER, GEORGE L) Apr 1, 1989 - Mar 31, 1995
    Role: Principal Investigator
  4. F32HD006959 (MUTTER, GEORGE L) Dec 6, 1986
    Role: Principal Investigator
  5. S07RR005950 (HOLMAN, B LEONARD) Apr 1, 1985 - Sep 29, 1992
    Role: Co-Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Mutter GL, Milstone DS, Hwang DH, Siegmund S, Bruce A. Measuring Digital Pathology Throughput and Tissue Dropouts. J Pathol Inform. 2022; 13:8. PMID: 35136675; PMCID: PMC8794031.
  2. Watkins JC, Downing MJ, Crous-Bou M, Busch EL, Chen M, De Vivo I, Mutter GL. Endometrial Tumor Classification by Histomorphology and Biomarkers in the Nurses' Health Study. J Cancer Epidemiol. 2021; 2021:8884364. PMID: 33986807; PMCID: PMC8093077.
  3. Papke DJ, Lohmann S, Downing M, Hufnagl P, Mutter GL. Computational augmentation of neoplastic endometrial glands in digital pathology displays. J Pathol. 2021 03; 253(3):258-267. PMID: 33165914.
    Citations: 1     Fields:    Translation:Humans
  4. Yu KH, Hu V, Wang F, Matulonis UA, Mutter GL, Golden JA, Kohane IS. Deciphering serous ovarian carcinoma histopathology and platinum response by convolutional neural networks. BMC Med. 2020 08 18; 18(1):236. PMID: 32807164.
    Citations: 3     Fields:    Translation:Humans
  5. Downing MJ, Papke DJ, Tyekucheva S, Mutter GL. A New Classification of Benign, Premalignant, and Malignant Endometrial Tissues Using Machine Learning Applied to 1413 Candidate Variables. Int J Gynecol Pathol. 2020 Jul; 39(4):333-343. PMID: 31157686.
    Citations:    Fields:    Translation:HumansCells
  6. Ditzel HM, Strickland KC, Meserve EE, Stover E, Konstantinopoulos PA, Matulonis UA, Muto MG, Liu JF, Feltmate C, Horowitz N, Berkowitz RS, Gupta M, Hecht JL, Lin DI, Jochumsen KM, Welch WR, Hirsch MS, Quade BJ, Lee KR, Crum CP, Mutter GL, Nucci MR, Howitt BE. Assessment of a Chemotherapy Response Score (CRS) System for Tubo-Ovarian High-Grade Serous Carcinoma (HGSC). Int J Gynecol Pathol. 2019 May; 38(3):230-240. PMID: 29750700.
    Citations: 7     Fields:    Translation:Humans
  7. Rabban JT, Gilks CB, Malpica A, Matias-Guiu X, Mittal K, Mutter GL, Oliva E, Parkash V, Ronnett BM, Staats P, Stewart CJR, McCluggage WG. Issues in the Differential Diagnosis of Uterine Low-grade Endometrioid Carcinoma, Including Mixed Endometrial Carcinomas: Recommendations from the International Society of Gynecological Pathologists. Int J Gynecol Pathol. 2019 Jan; 38 Suppl 1:S25-S39. PMID: 30550482; PMCID: PMC6296831.
    Citations: 7     Fields:    Translation:Humans
  8. Siregar P, Julen N, Hufnagl P, Mutter G. A general framework dedicated to computational morphogenesis Part II - Knowledge representation and architecture. Biosystems. 2018 Nov; 173:314-334. PMID: 30009873.
    Citations: 2     Fields:    Translation:HumansAnimals
  9. Herrmann MD, Clunie DA, Fedorov A, Doyle SW, Pieper S, Klepeis V, Le LP, Mutter GL, Milstone DS, Schultz TJ, Kikinis R, Kotecha GK, Hwang DH, Andriole KP, Iafrate AJ, Brink JA, Boland GW, Dreyer KJ, Michalski M, Golden JA, Louis DN, Lennerz JK. Implementing the DICOM Standard for Digital Pathology. J Pathol Inform. 2018; 9:37. PMID: 30533276; PMCID: PMC6236926.
    Citations: 27     
  10. Siregar P, Julen N, Hufnagl P, Mutter G. A general framework dedicated to computational morphogenesis Part I - Constitutive equations. Biosystems. 2018 Nov; 173:298-313. PMID: 30005999.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  11. Siregar P, Julen N, Hufnagl P, Mutter GL. Computational morphogenesis - Embryogenesis, cancer research and digital pathology. Biosystems. 2018 Jul; 169-170:40-54. PMID: 29859766.
    Citations: 1     Fields:    Translation:Humans
  12. Busch EL, Crous-Bou M, Prescott J, Downing MJ, Rosner BA, Mutter GL, De Vivo I. Adiponectin, Leptin, and Insulin-Pathway Receptors as Endometrial Cancer Subtyping Markers. Horm Cancer. 2018 02; 9(1):33-39. PMID: 29297146.
    Citations: 6     Fields:    Translation:Humans
  13. Longacre TA, Broaddus R, Chuang LT, Cohen MB, Jarboe EA, Mutter GL, Otis CN, Zaino RJ. Template for Reporting Results of Biomarker Testing of Specimens From Patients With Carcinoma of the Endometrium. Arch Pathol Lab Med. 2017 11; 141(11):1508-1512. PMID: 28301227.
    Citations: 6     Fields:    Translation:Humans
  14. Busch EL, Crous-Bou M, Prescott J, Chen MM, Downing MJ, Rosner BA, Mutter GL, De Vivo I. Endometrial Cancer Risk Factors, Hormone Receptors, and Mortality Prediction. Cancer Epidemiol Biomarkers Prev. 2017 05; 26(5):727-735. PMID: 28052940; PMCID: PMC5413416.
    Citations: 18     Fields:    Translation:Humans
  15. Saglam A, Usubütün A, Dolgun A, Mutter GL, Salman MC, Kurtulan O, Akyol A, Özkan EA, Baykara S, Bülbül D, Calay Z, Eren F, Gümürdülü D, Haberal N, Ilvan S, Karaveli S, Koyuncuoglu M, Müezzinoglu B, Müftüoglu KH, Özen Ö, Özdemir N, Pestereli E, Ulukus Ç, Zekioglu O. Diagnostic and Treatment Reproducibility of Cervical Intraepithelial Neoplasia / Squamous Intraepithelial Lesion and Factors Affecting the Diagnosis. Turk Patoloji Derg. 2017; 1(1):177-191. PMID: 28832077.
    Citations: 2     Fields:    Translation:HumansCells
  16. Asghar W, Shafiee H, Velasco V, Sah VR, Guo S, El Assal R, Inci F, Rajagopalan A, Jahangir M, Anchan RM, Mutter GL, Ozkan M, Ozkan CS, Demirci U. Toxicology Study of Single-walled Carbon Nanotubes and Reduced Graphene Oxide in Human Sperm. Sci Rep. 2016 08 19; 6:30270. PMID: 27538480.
    Citations: 16     Fields:    Translation:HumansCells
  17. Rappa KL, Rodriguez HF, Hakkarainen GC, Anchan RM, Mutter GL, Asghar W. Sperm processing for advanced reproductive technologies: Where are we today? Biotechnol Adv. 2016 Sep-Oct; 34(5):578-587. PMID: 26845061.
    Citations: 37     Fields:    Translation:HumansCells
  18. Howitt BE, Monte NM, Elvin J, Mutter GL. Dyssynchronous secretory endometrial glands often show sporadically acquired progesterone nonresponsiveness. Int J Gynecol Pathol. 2015 May; 34(3):239-44. PMID: 25844547.
    Citations:    Fields:    Translation:Humans
  19. Yang EJ, Mutter GL. Biomarker resolution of uterine smooth muscle tumor necrosis as benign vs malignant. Mod Pathol. 2015 Jun; 28(6):830-5. PMID: 25698060.
    Citations: 2     Fields:    Translation:Humans
  20. Nagymanyoki Z, Mutter GL, Hornick JL, Cibas ES. ARID1A is a useful marker of malignancy in peritoneal washings for endometrial carcinoma. Cancer Cytopathol. 2015 Apr; 123(4):253-7. PMID: 25557364.
    Citations: 4     Fields:    Translation:Humans
  21. Asghar W, Velasco V, Kingsley JL, Shoukat MS, Shafiee H, Anchan RM, Mutter GL, Tüzel E, Demirci U. Selection of functional human sperm with higher DNA integrity and fewer reactive oxygen species. Adv Healthc Mater. 2014 Oct; 3(10):1671-9. PMID: 24753434.
    Citations: 29     Fields:    Translation:HumansCells
  22. Mutter GL, Monte NM, Neuberg D, Ferenczy A, Eng C. Emergence, involution, and progression to carcinoma of mutant clones in normal endometrial tissues. Cancer Res. 2014 May 15; 74(10):2796-802. PMID: 24662919.
    Citations: 17     Fields:    Translation:Humans
  23. Parra-Herran CE, Monte NM, Mutter GL. Endometrial intraepithelial neoplasia with secretory differentiation: diagnostic features and underlying mechanisms. Mod Pathol. 2013 Jun; 26(6):868-73. PMID: 23328979.
    Citations:    Fields:    Translation:Humans
  24. Trimble CL, Method M, Leitao M, Lu K, Ioffe O, Hampton M, Higgins R, Zaino R, Mutter GL. Management of endometrial precancers. Obstet Gynecol. 2012 Nov; 120(5):1160-75. PMID: 23090535; PMCID: PMC3800154.
    Citations: 40     Fields:    Translation:Humans
  25. Quick CM, Laury AR, Monte NM, Mutter GL. Utility of PAX2 as a marker for diagnosis of endometrial intraepithelial neoplasia. Am J Clin Pathol. 2012 Nov; 138(5):678-84. PMID: 23086768.
    Citations: 7     Fields:    Translation:Humans
  26. Usubutun A, Mutter GL, Saglam A, Dolgun A, Ozkan EA, Ince T, Akyol A, Bulbul HD, Calay Z, Eren F, Gumurdulu D, Haberal AN, Ilvan S, Karaveli S, Koyuncuoglu M, Muezzinoglu B, Muftuoglu KH, Ozdemir N, Ozen O, Baykara S, Pestereli E, Ulukus EC, Zekioglu O. Reproducibility of endometrial intraepithelial neoplasia diagnosis is good, but influenced by the diagnostic style of pathologists. Mod Pathol. 2012 Jun; 25(6):877-84. PMID: 22301705.
    Citations: 4     Fields:    Translation:Humans
  27. Semere LG, Ko E, Johnson NR, Vitonis AF, Phang LJ, Cramer DW, Mutter GL. Endometrial intraepithelial neoplasia: clinical correlates and outcomes. Obstet Gynecol. 2011 Jul; 118(1):21-28. PMID: 21691159; PMCID: PMC3155976.
    Citations: 3     Fields:    Translation:Humans
  28. Jarboe EA, Mutter GL. Endometrial intraepithelial neoplasia. Semin Diagn Pathol. 2010 Nov; 27(4):215-25. PMID: 21309257.
    Citations: 10     Fields:    Translation:Humans
  29. Chen EY, Mehra K, Mehrad M, Ning G, Miron A, Mutter GL, Monte N, Quade BJ, McKeon FD, Yassin Y, Xian W, Crum CP. Secretory cell outgrowth, PAX2 and serous carcinogenesis in the Fallopian tube. J Pathol. 2010 Sep; 222(1):110-6. PMID: 20597068.
    Citations: 59     Fields:    Translation:Humans
  30. Huang EC, Mutter GL, Crum CP, Nucci MR. Clinical outcome in diagnostically ambiguous foci of 'gland crowding' in the endometrium. Mod Pathol. 2010 Nov; 23(11):1486-91. PMID: 20676062.
    Citations: 2     Fields:    Translation:Humans
  31. Monte NM, Webster KA, Neuberg D, Dressler GR, Mutter GL. Joint loss of PAX2 and PTEN expression in endometrial precancers and cancer. Cancer Res. 2010 Aug 01; 70(15):6225-32. PMID: 20631067.
    Citations: 35     Fields:    Translation:Humans
  32. Roh MH, Yassin Y, Miron A, Mehra KK, Mehrad M, Monte NM, Mutter GL, Nucci MR, Ning G, Mckeon FD, Hirsch MS, Wa X, Crum CP. High-grade fimbrial-ovarian carcinomas are unified by altered p53, PTEN and PAX2 expression. Mod Pathol. 2010 Oct; 23(10):1316-24. PMID: 20562848.
    Citations: 40     Fields:    Translation:Humans
  33. Jarboe EA, Miron A, Carlson JW, Hirsch MS, Kindelberger D, Mutter GL, Crum CP, Nucci MR. Coexisting intraepithelial serous carcinomas of the endometrium and fallopian tube: frequency and potential significance. Int J Gynecol Pathol. 2009 Jul; 28(4):308-15. PMID: 19483636.
    Citations: 26     Fields:    Translation:Humans
  34. Lin MC, Burkholder KA, Viswanathan AN, Neuberg D, Mutter GL. Involution of latent endometrial precancers by hormonal and nonhormonal mechanisms. Cancer. 2009 May 15; 115(10):2111-8. PMID: 19280590; PMCID: PMC2745907.
    Citations: 9     Fields:    Translation:Humans
  35. Jarboe EA, Pizer ES, Miron A, Monte N, Mutter GL, Crum CP. Evidence for a latent precursor (p53 signature) that may precede serous endometrial intraepithelial carcinoma. Mod Pathol. 2009 Mar; 22(3):345-50. PMID: 19151662.
    Citations: 17     Fields:    Translation:Humans
  36. Ioffe OB, Zaino RJ, Mutter GL. Endometrial changes from short-term therapy with CDB-4124, a selective progesterone receptor modulator. Mod Pathol. 2009 Mar; 22(3):450-9. PMID: 19136935.
    Citations: 21     Fields:    Translation:HumansCTClinical Trials
  37. Lacey JV, Mutter GL, Nucci MR, Ronnett BM, Ioffe OB, Rush BB, Glass AG, Richesson DA, Chatterjee N, Langholz B, Sherman ME. Risk of subsequent endometrial carcinoma associated with endometrial intraepithelial neoplasia classification of endometrial biopsies. Cancer. 2008 Oct 15; 113(8):2073-81. PMID: 18720479; PMCID: PMC2587088.
    Citations: 15     Fields:    Translation:Humans
  38. Lin MC, Lomo L, Baak JP, Eng C, Ince TA, Crum CP, Mutter GL. Squamous morules are functionally inert elements of premalignant endometrial neoplasia. Mod Pathol. 2009 Feb; 22(2):167-74. PMID: 19180120.
    Citations: 9     Fields:    Translation:Humans
  39. Carlson JW, Mutter GL. Endometrial intraepithelial neoplasia is associated with polyps and frequently has metaplastic change. Histopathology. 2008 Sep; 53(3):325-32. PMID: 18637968.
    Citations: 9     Fields:    Translation:HumansCells
  40. Lacey JV, Mutter GL, Ronnett BM, Ioffe OB, Duggan MA, Rush BB, Glass AG, Richesson DA, Chatterjee N, Langholz B, Sherman ME. PTEN expression in endometrial biopsies as a marker of progression to endometrial carcinoma. Cancer Res. 2008 Jul 15; 68(14):6014-20. PMID: 18632658.
    Citations: 23     Fields:    Translation:Humans
  41. Lomo L, Nucci MR, Lee KR, Lin MC, Hirsch MS, Crum CP, Mutter GL. Histologic and immunohistochemical decision-making in endometrial adenocarcinoma. Mod Pathol. 2008 Aug; 21(8):937-42. PMID: 18500258.
    Citations: 7     Fields:    Translation:Humans
  42. Mutter GL, Kauderer J, Baak JP, Alberts D. Biopsy histomorphometry predicts uterine myoinvasion by endometrial carcinoma: a Gynecologic Oncology Group study. Hum Pathol. 2008 Jun; 39(6):866-74. PMID: 18436277.
    Citations: 13     Fields:    Translation:Humans
  43. Mutter GL, Bergeron C, Deligdisch L, Ferenczy A, Glant M, Merino M, Williams AR, Blithe DL. The spectrum of endometrial pathology induced by progesterone receptor modulators. Mod Pathol. 2008 May; 21(5):591-8. PMID: 18246050.
    Citations: 53     Fields:    Translation:Humans
  44. Patocs A, Zhang L, Xu Y, Weber F, Caldes T, Mutter GL, Platzer P, Eng C. Breast-cancer stromal cells with TP53 mutations and nodal metastases. N Engl J Med. 2007 Dec 20; 357(25):2543-51. PMID: 18094375.
    Citations: 140     Fields:    Translation:HumansCells
  45. Fukino K, Shen L, Patocs A, Mutter GL, Eng C. Genomic instability within tumor stroma and clinicopathological characteristics of sporadic primary invasive breast carcinoma. JAMA. 2007 May 16; 297(19):2103-11. PMID: 17507346.
    Citations: 53     Fields:    Translation:HumansCells
  46. Mutter GL, Zaino RJ, Baak JP, Bentley RC, Robboy SJ. Benign endometrial hyperplasia sequence and endometrial intraepithelial neoplasia. Int J Gynecol Pathol. 2007 Apr; 26(2):103-14. PMID: 17413975.
    Citations: 30     Fields:    Translation:Humans
  47. Berman JJ, Albores-Saavedra J, Bostwick D, Delellis R, Eble J, Hamilton SR, Hruban RH, Mutter GL, Page D, Rohan T, Travis W, Henson DE. Precancer: a conceptual working definition -- results of a Consensus Conference. Cancer Detect Prev. 2006; 30(5):387-94. PMID: 17079091.
    Citations: 25     Fields:    Translation:Humans
  48. Hecht JL, Mutter GL. Molecular and pathologic aspects of endometrial carcinogenesis. J Clin Oncol. 2006 Oct 10; 24(29):4783-91. PMID: 17028294.
    Citations: 152     Fields:    Translation:Humans
  49. Ørbo A, Rise CE, Mutter GL. Regression of latent endometrial precancers by progestin infiltrated intrauterine device. Cancer Res. 2006 Jun 01; 66(11):5613-7. PMID: 16740697; PMCID: PMC2573866.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  50. Weber F, Shen L, Fukino K, Patocs A, Mutter GL, Caldes T, Eng C. Total-genome analysis of BRCA1/2-related invasive carcinomas of the breast identifies tumor stroma as potential landscaper for neoplastic initiation. Am J Hum Genet. 2006 Jun; 78(6):961-72. PMID: 16685647.
    Citations: 36     Fields:    Translation:HumansCells
  51. Baak JP, Mutter GL, Robboy S, van Diest PJ, Uyterlinde AM, Orbo A, Palazzo J, Fiane B, Løvslett K, Burger C, Voorhorst F, Verheijen RH. The molecular genetics and morphometry-based endometrial intraepithelial neoplasia classification system predicts disease progression in endometrial hyperplasia more accurately than the 1994 World Health Organization classification system. Cancer. 2005 Jun 01; 103(11):2304-12. PMID: 15856484; PMCID: PMC2600877.
    Citations: 35     Fields:    Translation:Humans
  52. Weber F, Fukino K, Sawada T, Williams N, Sweet K, Brena RM, Plass C, Caldes T, Mutter GL, Villalona-Calero MA, Eng C. Variability in organ-specific EGFR mutational spectra in tumour epithelium and stroma may be the biological basis for differential responses to tyrosine kinase inhibitors. Br J Cancer. 2005 May 23; 92(10):1922-6. PMID: 15841079; PMCID: PMC2361765.
    Citations: 27     Fields:    Translation:HumansCells
  53. Baak JP, Van Diermen B, Steinbakk A, Janssen E, Skaland I, Mutter GL, Fiane B, Løvslett K. Lack of PTEN expression in endometrial intraepithelial neoplasia is correlated with cancer progression. Hum Pathol. 2005 May; 36(5):555-61. PMID: 15948123.
    Citations: 14     Fields:    Translation:Humans
  54. Hecht JL, Ince TA, Baak JP, Baker HE, Ogden MW, Mutter GL. Prediction of endometrial carcinoma by subjective endometrial intraepithelial neoplasia diagnosis. Mod Pathol. 2005 Mar; 18(3):324-30. PMID: 15529181; PMCID: PMC2573865.
    Citations: 21     Fields:    Translation:Humans
  55. Baak JP, Mutter GL. EIN and WHO94. J Clin Pathol. 2005 Jan; 58(1):1-6. PMID: 15623473; PMCID: PMC1770545.
    Citations: 18     Fields:    Translation:Humans
  56. Mutter GL, Zahrieh D, Liu C, Neuberg D, Finkelstein D, Baker HE, Warrington JA. Comparison of frozen and RNALater solid tissue storage methods for use in RNA expression microarrays. BMC Genomics. 2004 Nov 10; 5:88. PMID: 15537428.
    Citations: 64     Fields:    Translation:HumansCells
  57. Fukino K, Shen L, Matsumoto S, Morrison CD, Mutter GL, Eng C. Combined total genome loss of heterozygosity scan of breast cancer stroma and epithelium reveals multiplicity of stromal targets. Cancer Res. 2004 Oct 15; 64(20):7231-6. PMID: 15492239.
    Citations: 60     Fields:    Translation:HumansCells
  58. Quade BJ, Wang TY, Sornberger K, Dal Cin P, Mutter GL, Morton CC. Molecular pathogenesis of uterine smooth muscle tumors from transcriptional profiling. Genes Chromosomes Cancer. 2004 Jun; 40(2):97-108. PMID: 15101043.
    Citations: 46     Fields:    Translation:HumansCells
  59. Zheng W, Baker HE, Mutter GL. Involution of PTEN-null endometrial glands with progestin therapy. Gynecol Oncol. 2004 Mar; 92(3):1008-13. PMID: 14984979.
    Citations: 11     Fields:    Translation:Humans
  60. Crum CP, Hornstein MD, Nucci MR, Mutter GL. Hertig and beyond: a systematic and practical approach to the endometrial biopsy. Adv Anat Pathol. 2003 Nov; 10(6):301-18. PMID: 14581820.
    Citations: 2     Fields:    Translation:Humans
  61. Styer AK, Cekleniak NA, Legedza A, Mutter GL, Hornstein MD. Factors associated with disposition of cryopreserved reproductive tissue. Fertil Steril. 2003 Sep; 80(3):584-9. PMID: 12969702.
    Citations: 3     Fields:    Translation:Humans
  62. Tadesse MG, Ibrahim JG, Mutter GL. Identification of differentially expressed genes in high-density oligonucleotide arrays accounting for the quantification limits of the technology. Biometrics. 2003 Sep; 59(3):542-54. PMID: 14601755.
    Citations: 4     Fields:    Translation:Humans
  63. Nucci MR, Castrillon DH, Bai H, Quade BJ, Ince TA, Genest DR, Lee KR, Mutter GL, Crum CP. Biomarkers in diagnostic obstetric and gynecologic pathology: a review. Adv Anat Pathol. 2003 Mar; 10(2):55-68. PMID: 12605088.
    Citations: 11     Fields:    Translation:Humans
  64. Ince TA, Cviko AP, Quade BJ, Yang A, McKeon FD, Mutter GL, Crum CP. p63 Coordinates anogenital modeling and epithelial cell differentiation in the developing female urogenital tract. Am J Pathol. 2002 Oct; 161(4):1111-7. PMID: 12368184; PMCID: PMC1867285.
    Citations: 23     Fields:    Translation:AnimalsCells
  65. Wright TC, Holinka CF, Ferenczy A, Gatsonis CA, Mutter GL, Nicosia S, Richart RM. Estradiol-induced hyperplasia in endometrial biopsies from women on hormone replacement therapy. Am J Surg Pathol. 2002 Oct; 26(10):1269-75. PMID: 12360041.
    Citations: 1     Fields:    Translation:Humans
  66. Mutter GL. Diagnosis of premalignant endometrial disease. J Clin Pathol. 2002 May; 55(5):326-31. PMID: 11986334; PMCID: PMC1769645.
    Citations: 18     Fields:    Translation:Humans
  67. Hsiao LL, Dangond F, Yoshida T, Hong R, Jensen RV, Misra J, Dillon W, Lee KF, Clark KE, Haverty P, Weng Z, Mutter GL, Frosch MP, MacDonald ME, Milford EL, Crum CP, Bueno R, Pratt RE, Mahadevappa M, Warrington JA, Stephanopoulos G, Stephanopoulos G, Gullans SR. A compendium of gene expression in normal human tissues. Physiol Genomics. 2001 Dec 21; 7(2):97-104. PMID: 11773596.
    Citations: 172     Fields:    Translation:Humans
  68. Mutter GL, Baak JP, Fitzgerald JT, Gray R, Neuberg D, Kust GA, Gentleman R, Gullans SR, Wei LJ, Wilcox M. Global expression changes of constitutive and hormonally regulated genes during endometrial neoplastic transformation. Gynecol Oncol. 2001 Nov; 83(2):177-85. PMID: 11606070.
    Citations: 40     Fields:    Translation:HumansCells
  69. Johnson EB, Muto MG, Yanushpolsky EH, Mutter GL. Phytoestrogen supplementation and endometrial cancer. Obstet Gynecol. 2001 Nov; 98(5 Pt 2):947-50. PMID: 11704216.
    Citations: 2     Fields:    Translation:HumansAnimals
  70. Mutter GL. Pten, a protean tumor suppressor. Am J Pathol. 2001 Jun; 158(6):1895-8. PMID: 11395362; PMCID: PMC1891981.
    Citations: 31     Fields:    Translation:Humans
  71. Mutter GL, Ince TA, Baak JP, Kust GA, Zhou XP, Eng C. Molecular identification of latent precancers in histologically normal endometrium. Cancer Res. 2001 Jun 01; 61(11):4311-4. PMID: 11389050.
    Citations: 47     Fields:    Translation:Humans
  72. O'Connell JT, Mutter GL, Cviko A, Nucci M, Quade BJ, Kozakewich HP, Neffen E, Sun D, Yang A, McKeon FD, Crum CP. Identification of a basal/reserve cell immunophenotype in benign and neoplastic endometrium: a study with the p53 homologue p63. Gynecol Oncol. 2001 Jan; 80(1):30-6. PMID: 11136566.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  73. Biswas DK, Cruz A, Pettit N, Mutter GL, Pardee AB. A therapeutic target for hormone-independent estrogen receptor-positive breast cancers. Mol Med. 2001 Jan; 7(1):59-67. PMID: 11474128; PMCID: PMC1949989.
    Citations: 2     Fields:    Translation:HumansCells
  74. Mutter GL. Histopathology of genetically defined endometrial precancers. Int J Gynecol Pathol. 2000 Oct; 19(4):301-9. PMID: 11109157.
    Citations: 24     Fields:    Translation:Humans
  75. Faquin WC, Fitzgerald JT, Boynton KA, Mutter GL. Intratumoral genetic heterogeneity and progression of endometrioid type endometrial adenocarcinomas. Gynecol Oncol. 2000 Aug; 78(2):152-7. PMID: 10926795.
    Citations: 4     Fields:    Translation:HumansCells
  76. Mutter GL, Lin MC, Fitzgerald JT, Kum JB, Baak JP, Lees JA, Weng LP, Eng C. Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers. J Natl Cancer Inst. 2000 Jun 07; 92(11):924-30. PMID: 10841828.
    Citations: 213     Fields:    Translation:Humans
  77. Mutter GL, Lin MC, Fitzgerald JT, Kum JB, Eng C. Changes in endometrial PTEN expression throughout the human menstrual cycle. J Clin Endocrinol Metab. 2000 Jun; 85(6):2334-8. PMID: 10852473.
    Citations: 26     Fields:    Translation:HumansCells
  78. Gimm O, Perren A, Weng LP, Marsh DJ, Yeh JJ, Ziebold U, Gil E, Hinze R, Delbridge L, Lees JA, Mutter GL, Robinson BG, Komminoth P, Dralle H, Eng C. Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumors. Am J Pathol. 2000 May; 156(5):1693-700. PMID: 10793080; PMCID: PMC1876937.
    Citations: 102     Fields:    Translation:HumansCells
  79. Martin KJ, Kritzman BM, Price LM, Koh B, Kwan CP, Zhang X, Mackay A, O'Hare MJ, Kaelin CM, Mutter GL, Pardee AB, Sager R. Linking gene expression patterns to therapeutic groups in breast cancer. Cancer Res. 2000 Apr 15; 60(8):2232-8. PMID: 10786689.
    Citations: 18     Fields:    Translation:HumansCells
  80. Yeh JJ, Lunetta KL, van Orsouw NJ, Moore FD, Mutter GL, Vijg J, Dahia PL, Eng C. Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours. Oncogene. 2000 Apr 13; 19(16):2060-6. PMID: 10803467.
    Citations: 53     Fields:    Translation:Humans
  81. Faquin WC, Fitzgerald JT, Lin MC, Boynton KA, Muto MG, Mutter GL. Sporadic microsatellite instability is specific to neoplastic and preneoplastic endometrial tissues. Am J Clin Pathol. 2000 Apr; 113(4):576-82. PMID: 10787358.
    Citations: 5     Fields:    Translation:HumansCells
  82. Mutter GL. Endometrial intraepithelial neoplasia (EIN): will it bring order to chaos? The Endometrial Collaborative Group. Gynecol Oncol. 2000 Mar; 76(3):287-90. PMID: 10684697.
    Citations: 43     Fields:    Translation:Humans
  83. Mutter GL, Baak JP, Crum CP, Richart RM, Ferenczy A, Faquin WC. Endometrial precancer diagnosis by histopathology, clonal analysis, and computerized morphometry. J Pathol. 2000 Mar; 190(4):462-9. PMID: 10699996.
    Citations: 33     Fields:    Translation:Humans
  84. Nucci MR, Prasad CJ, Crum CP, Mutter GL. Mucinous endometrial epithelial proliferations: a morphologic spectrum of changes with diverse clinical significance. Mod Pathol. 1999 Dec; 12(12):1137-42. PMID: 10619266.
    Citations: 12     Fields:    Translation:HumansCells
  85. Esteller M, Catasus L, Matias-Guiu X, Mutter GL, Prat J, Baylin SB, Herman JG. hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis. Am J Pathol. 1999 Nov; 155(5):1767-72. PMID: 10550333; PMCID: PMC1866976.
    Citations: 51     Fields:    Translation:HumansCells
  86. Mutter GL, Wada H, Faquin WC, Enomoto T. K-ras mutations appear in the premalignant phase of both microsatellite stable and unstable endometrial carcinogenesis. Mol Pathol. 1999 Oct; 52(5):257-62. PMID: 10748874; PMCID: PMC395707.
    Citations: 13     Fields:    Translation:HumansCells
  87. Perren A, Weng LP, Boag AH, Ziebold U, Thakore K, Dahia PL, Komminoth P, Lees JA, Mulligan LM, Mutter GL, Eng C. Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast. Am J Pathol. 1999 Oct; 155(4):1253-60. PMID: 10514407; PMCID: PMC1867038.
    Citations: 118     Fields:    Translation:HumansCells
  88. Pinto AP, Lin MC, Mutter GL, Sun D, Villa LL, Crum CP. Allelic loss in human papillomavirus-positive and -negative vulvar squamous cell carcinomas. Am J Pathol. 1999 Apr; 154(4):1009-15. PMID: 10233839; PMCID: PMC1866571.
    Citations: 11     Fields:    Translation:HumansCells
  89. Ford HL, Kabingu EN, Bump EA, Mutter GL, Pardee AB. Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: a possible mechanism of breast carcinogenesis. Proc Natl Acad Sci U S A. 1998 Oct 13; 95(21):12608-13. PMID: 9770533; PMCID: PMC22878.
    Citations: 77     Fields:    Translation:HumansCells
  90. Lin MC, Mutter GL, Trivijisilp P, Boynton KA, Sun D, Crum CP. Patterns of allelic loss (LOH) in vulvar squamous carcinomas and adjacent noninvasive epithelia. Am J Pathol. 1998 May; 152(5):1313-8. PMID: 9588899; PMCID: PMC1858564.
    Citations: 6     Fields:    Translation:HumansCells
  91. Mutter GL. Role of imprinting in abnormal human development. Mutat Res. 1997 Dec 12; 396(1-2):141-7. PMID: 9434865.
    Citations: 4     Fields:    Translation:Humans
  92. Quade BJ, McLachlin CM, Soto-Wright V, Zuckerman J, Mutter GL, Morton CC. Disseminated peritoneal leiomyomatosis. Clonality analysis by X chromosome inactivation and cytogenetics of a clinically benign smooth muscle proliferation. Am J Pathol. 1997 Jun; 150(6):2153-66. PMID: 9176406; PMCID: PMC1858338.
    Citations: 10     Fields:    Translation:HumansCells
  93. Stewart CL, Pedersen R, Rotwein P, Bestor T, Rastan S, Hastie N, Nichols R, Mutter G. NIEHS/EPA Workshops. Genomic imprinting. Reprod Toxicol. 1997 Mar-Jun; 11(2-3):309-16. PMID: 9100305.
    Citations:    Fields:    Translation:HumansAnimalsCells
  94. Crum CP, McLachlin CM, Tate JE, Mutter GL. Pathobiology of vulvar squamous neoplasia. Curr Opin Obstet Gynecol. 1997 Feb; 9(1):63-9. PMID: 9090485.
    Citations: 15     Fields:    Translation:HumansCells
  95. Menke DB, Mutter GL, Page DC. Expression of DAZ, an azoospermia factor candidate, in human spermatogonia. Am J Hum Genet. 1997 Jan; 60(1):237-41. PMID: 8981970; PMCID: PMC1712565.
    Citations: 19     Fields:    Translation:HumansCells
  96. Tate JE, Mutter GL, Boynton KA, Crum CP. Monoclonal origin of vulvar intraepithelial neoplasia and some vulvar hyperplasias. Am J Pathol. 1997 Jan; 150(1):315-22. PMID: 9006346; PMCID: PMC1858508.
    Citations: 6     Fields:    Translation:HumansCells
  97. Sinnock KL, Perez-Atayde AR, Boynton KA, Mutter GL. Clonal analysis of sacrococcygeal "teratomas". Pediatr Pathol Lab Med. 1996 Nov-Dec; 16(6):865-75. PMID: 9025885.
    Citations: 1     Fields:    Translation:Humans
  98. Mutter GL, Boynton KA, Faquin WC, Ruiz RE, Jovanovic AS. Allelotype mapping of unstable microsatellites establishes direct lineage continuity between endometrial precancers and cancer. Cancer Res. 1996 Oct 01; 56(19):4483-6. PMID: 8813144.
    Citations: 19     Fields:    Translation:HumansCells
  99. Jovanovic AS, Boynton KA, Mutter GL. Uteri of women with endometrial carcinoma contain a histopathological spectrum of monoclonal putative precancers, some with microsatellite instability. Cancer Res. 1996 Apr 15; 56(8):1917-21. PMID: 8620514.
    Citations: 19     Fields:    Translation:HumansCells
  100. Mutter GL, Boynton KA. X chromosome inactivation in the normal female genital tract: implications for identification of neoplasia. Cancer Res. 1995 Nov 01; 55(21):5080-4. PMID: 7585555.
    Citations: 10     Fields:    Translation:HumansCells
  101. Mutter GL, Boynton KA. PCR bias in amplification of androgen receptor alleles, a trinucleotide repeat marker used in clonality studies. Nucleic Acids Res. 1995 Apr 25; 23(8):1411-8. PMID: 7753634; PMCID: PMC306870.
    Citations: 44     Fields:    Translation:HumansCells
  102. Mutter GL, Chaponot ML, Fletcher JA. A polymerase chain reaction assay for non-random X chromosome inactivation identifies monoclonal endometrial cancers and precancers. Am J Pathol. 1995 Feb; 146(2):501-8. PMID: 7856759; PMCID: PMC1869842.
    Citations: 21     Fields:    Translation:HumansCells
  103. Borriello F, Weinberg DS, Mutter GL. Evaluation of gene deletions by quantitative polymerase chain reaction. Experience with the alpha-thalassemia model. Diagn Mol Pathol. 1994 Dec; 3(4):246-54. PMID: 7866634.
    Citations: 2     Fields:    Translation:HumansCells
  104. McLachlin CM, Mutter GL, Crum CP. Multinucleated atypia of the vulva. Report of a distinct entity not associated with human papillomavirus. Am J Surg Pathol. 1994 Dec; 18(12):1233-9. PMID: 7977946.
    Citations: 1     Fields:    Translation:HumansCells
  105. Zitz JC, McLachlin CM, Tate JE, Mutter GL, Crum CP. Restriction fragment length polymorphism analysis of isotype-labeled polymerase chain reaction-amplified human papillomavirus DNA combines sensitivity with built-in contaminant detection. Mod Pathol. 1994 Apr; 7(3):407-11. PMID: 7914697.
    Citations: 2     Fields:    Translation:HumansCells
  106. Tate JE, Mutter GL, Prasad CJ, Berkowitz R, Goodman H, Crum CP. Analysis of HPV-positive and -negative vulvar carcinomas for alterations in c-myc, Ha-, Ki-, and N-ras genes. Gynecol Oncol. 1994 Apr; 53(1):78-83. PMID: 8175026.
    Citations: 1     Fields:    Translation:HumansCells
  107. Roberts DJ, Mutter GL. Advances in the molecular biology of gestational trophoblastic disease. J Reprod Med. 1994 Mar; 39(3):201-8. PMID: 8035375.
    Citations: 2     Fields:    Translation:HumansAnimals
  108. Mutter GL, Stewart CL, Chaponot ML, Pomponio RJ. Oppositely imprinted genes H19 and insulin-like growth factor 2 are coexpressed in human androgenetic trophoblast. Am J Hum Genet. 1993 Nov; 53(5):1096-102. PMID: 7692725; PMCID: PMC1682317.
    Citations: 13     Fields:    Translation:HumansCells
  109. Iwaoki Y, Matsuda H, Mutter GL, Watrin F, Wolgemuth DJ. Differential expression of the proto-oncogenes c-abl and c-mos in developing mouse germ cells. Exp Cell Res. 1993 Jun; 206(2):212-9. PMID: 7684693.
    Citations: 4     Fields:    Translation:AnimalsCells
  110. Mutter GL, Pomponio RJ, Berkowitz RS, Genest DR. Sex chromosome composition of complete hydatidiform moles: relationship to metastasis. Am J Obstet Gynecol. 1993 May; 168(5):1547-51. PMID: 8498441.
    Citations: 1     Fields:    Translation:HumansCells
  111. Lobel SM, Pomponio RJ, Mutter GL. The sex ratio of normal and manipulated human sperm quantitated by the polymerase chain reaction. Fertil Steril. 1993 Feb; 59(2):387-92. PMID: 8425636.
    Citations: 5     Fields:    Translation:HumansCells
  112. Hornstein MD, Cohen JN, Thomas PP, Gleason RE, Friedman AJ, Mutter GL. The effect of consecutive day inseminations on semen characteristics in an intrauterine insemination program. Fertil Steril. 1992 Aug; 58(2):433-5. PMID: 1633917.
    Citations: 2     Fields:    Translation:Humans
  113. Mutter GL, Pomponio RJ. Molecular diagnosis of sex chromosome aneuploidy using quantitative PCR. Nucleic Acids Res. 1991 Aug 11; 19(15):4203-7. PMID: 1678507; PMCID: PMC328563.
    Citations: 3     Fields:    Translation:HumansCells
  114. Robertson NG, Pomponio RJ, Mutter GL, Morton CC. Testis-specific expression of the human MYCL2 gene. Nucleic Acids Res. 1991 Jun 11; 19(11):3129-37. PMID: 1711681; PMCID: PMC328281.
    Citations: 5     Fields:    Translation:HumansCells
  115. Martin DI, Zon LI, Mutter G, Orkin SH. Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages. Nature. 1990 Mar 29; 344(6265):444-7. PMID: 2320112.
    Citations: 125     Fields:    Translation:HumansAnimalsCells
  116. Balling R, Mutter G, Gruss P, Kessel M. Craniofacial abnormalities induced by ectopic expression of the homeobox gene Hox-1.1 in transgenic mice. Cell. 1989 Jul 28; 58(2):337-47. PMID: 2568891.
    Citations: 40     Fields:    Translation:AnimalsCells
  117. Mutter GL, Grills GS, Wolgemuth DJ. Evidence for the involvement of the proto-oncogene c-mos in mammalian meiotic maturation and possibly very early embryogenesis. EMBO J. 1988 Mar; 7(3):683-9. PMID: 2840283; PMCID: PMC454373.
    Citations: 13     Fields:    Translation:Cells
  118. Mutter GL. Teratoma genetics and stem cells: a review. Obstet Gynecol Surv. 1987 Nov; 42(11):661-70. PMID: 3317165.
    Citations: 4     Fields:    Translation:HumansCells
  119. Mutter GL, Wolgemuth DJ. Distinct developmental patterns of c-mos protooncogene expression in female and male mouse germ cells. Proc Natl Acad Sci U S A. 1987 Aug; 84(15):5301-5. PMID: 3474657; PMCID: PMC298843.
    Citations: 33     Fields:    Translation:AnimalsCells
  120. Dee GJ, Austin JH, Mutter GL. Bleomycin-associated pulmonary fibrosis: rapidly fatal progression without chest radiotherapy. J Surg Oncol. 1987 Jun; 35(2):135-8. PMID: 2438515.
    Citations:    Fields:    Translation:Humans
  121. Mutter GL, Stacey A, Wolgemuth DJ. Differential expression in murine somatic and germinal tissues of transcripts homologous to an abundant embryonal-carcinoma-cell mRNA. Differentiation. 1987; 34(2):126-30. PMID: 3622950.
    Citations:    Fields:    Translation:AnimalsCells
  122. Wolgemuth DJ, Engelmyer E, Duggal RN, Gizang-Ginsberg E, Mutter GL, Ponzetto C, Viviano C, Zakeri ZF. Isolation of a mouse cDNA coding for a developmentally regulated, testis-specific transcript containing homeo box homology. EMBO J. 1986 Jun; 5(6):1229-35. PMID: 2426103; PMCID: PMC1166932.
    Citations: 28     Fields:    Translation:AnimalsCells
  123. Keen M, Conley J, McBride T, Mutter G, Silver J. Pseudotumor of the pterygomaxillary space presenting as anesthesia of the mandibular nerve. Laryngoscope. 1986 May; 96(5):560-3. PMID: 3702571.
    Citations: 3     Fields:    Translation:Humans
  124. Mutter G. School health education in Canada: an interview with Gordon Mutter. J Sch Health. 1986 Feb; 56(2):48-51. PMID: 3633362.
    Citations:    Fields:    Translation:Humans
  125. Kensler TW, Mutter G, Hankerson JG, Reck LJ, Harley C, Han N, Ardalan B, Cysyk RL, Johnson RK, Jayaram HN, Cooney DA. Mechanism of resistance of variants of the Lewis lung carcinoma to N-(phosphonacetyl)-L-aspartic acid. Cancer Res. 1981 Mar; 41(3):894-904. PMID: 7459875.
    Citations: 3     Fields:    Translation:AnimalsCells
  126. Archer J, Kaye R, Mutter G. Control of streptozotocin diabetes in Chinese hamsters by cultured mouse islet cells without immunosuppression: a preliminary report. J Surg Res. 1980 Jan; 28(1):77-85. PMID: 6767141.
    Citations: 6     Fields:    Translation:AnimalsCells
  127. Mutter G. Barriers to the establishment of a regular dental program for elementary schools. Dent J. 1978 Jul-Aug; 44(7):316, 319. PMID: 279457.
    Citations:    Fields:    Translation:HumansPHPublic Health
  128. Mutter G. Smoking in the school environment. Can J Public Health. 1978 May-Jun; 69(3):197-8. PMID: 667765.
    Citations:    Fields:    Translation:Humans
  129. Mutter G. Effects of teacher training. Dent J. 1976 Feb; 42(2):78-9. PMID: 1062374.
    Citations:    Fields:    Translation:PHPublic Health
  130. Mutter GL. Jivaro tsantsas, authentic and forged: a study of two shrunken heads in the Mütter Museum. Trans Stud Coll Physicians Phila. 1975 Oct; 43(2):78-82. PMID: 45773.
    Citations: 1     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.