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Manoj Bhasin, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL086741 (LOGERFO, FRANK W) Feb 1, 2007 - Dec 31, 2022
    NIH/NHLBI
    Genetic Engineering of Vein Bypass Grafts in Vascular and Cardiovascular Surgery
    Role: Co-Principal Investigator
This researcher has shared information about their research resources in the eagle-i Network. To update or add resource records, contact eagle-i@hms.harvard.edu.
BIDMC Genomics, Proteomics, Bioinformatics and Systems Biology Center - Core services (6), Instruments (18), Microarrays (1), Protocols (8) and Software (23)
Bioinformatics & Systems Biology Core (BIDMC) - Core services (1) and Software (16)

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Mugoni V, Panella R, Cheloni G, Chen M, Pozdnyakova O, Stroopinsky D, Guarnerio J, Monteleone E, Lee JD, Mendez L, Menon AV, Aster JC, Lane AA, Stone RM, Galinsky I, Zamora JC, Lo-Coco F, Bhasin MK, Avigan D, Longo L, Clohessy JG, Pandolfi PP. Vulnerabilities in mIDH2 AML confer sensitivity to APL-like targeted combination therapy. Cell Res. 2019 Jun; 29(6):446-459. PMID: 31024166.
    Citations:    
  2. Lynch MR, Tran MT, Ralto KM, Zsengeller ZK, Raman V, Bhasin SS, Sun N, Chen X, Brown D, Rovira II, Taguchi K, Brooks CR, Stillman IE, Bhasin MK, Finkel T, Parikh SM. TFEB-driven lysosomal biogenesis is pivotal for PGC1a-dependent renal stress resistance. JCI Insight. 2019 Mar 14; 5. PMID: 30870143.
    Citations:    
  3. Chen CH, Bhasin S, Khanna P, Joshi M, Joslin PM, Saxena R, Amin S, Liu S, Sindhu S, Walker SR, Catalano P, Frank DA, Alper SL, Bhasin M, Bhatt RS. Study of Cathepsin B inhibition in VEGFR TKI treated human renal cell carcinoma xenografts. Oncogenesis. 2019 Feb 22; 8(3):15. PMID: 30796200.
    Citations:    
  4. Khatri I, Ganguly K, Sharma S, Carmicheal J, Kaur S, Batra SK, Bhasin MK. Systems Biology Approach to Identify Novel Genomic Determinants for Pancreatic Cancer Pathogenesis. Sci Rep. 2019 Jan 15; 9(1):123. PMID: 30644396.
    Citations:    Fields:    
  5. Arya AK, Bhadada SK, Singh P, Dahiya D, Kaur G, Sharma S, Saikia UN, Behera A, Rao SD, Bhasin M. Quantitative proteomics analysis of sporadic parathyroid adenoma tissue samples. J Endocrinol Invest. 2019 May; 42(5):577-590. PMID: 30284223.
    Citations:    Fields:    
  6. Russo JW, Gao C, Bhasin SS, Voznesensky OS, Calagua C, Arai S, Nelson PS, Montgomery B, Mostaghel EA, Corey E, Taplin ME, Ye H, Bhasin M, Balk SP. Downregulation of Dipeptidyl Peptidase 4 Accelerates Progression to Castration-Resistant Prostate Cancer. Cancer Res. 2018 Nov 15; 78(22):6354-6362. PMID: 30242112.
    Citations:    Fields:    
  7. Skibsted S, Bhasin MK, Henning DJ, Jaminet SC, Lewandowski J, Kirkegaard H, Aird WC, Shapiro NI. Leukocyte Transcriptional Response in Sepsis. Shock. 2018 Sep 11. PMID: 30211758.
    Citations:    Fields:    
  8. Prete A, Lo AS, Sadow PM, Bhasin SS, Antonello ZA, Vodopivec DM, Ullas S, Sims JN, Clohessy J, Dvorak AM, Sciuto T, Bhasin M, Murphy-Ullrich JE, Lawler J, Karumanchi SA, Nucera C. Pericytes Elicit Resistance to Vemurafenib and Sorafenib Therapy in Thyroid Carcinoma via the TSP-1/TGFß1 Axis. Clin Cancer Res. 2018 Dec 01; 24(23):6078-6097. PMID: 30076136.
    Citations:    Fields:    
  9. Singh PK, Khatri I, Jha A, Pretto CD, Spindler KR, Arumugaswami V, Giri S, Kumar A, Bhasin MK. Determination of system level alterations in host transcriptome due to Zika virus (ZIKV) Infection in retinal pigment epithelium. Sci Rep. 2018 Jul 25; 8(1):11209. PMID: 30046058.
    Citations: 1     Fields:    
  10. Chang J, Bhasin SS, Bielenberg DR, Sukhatme VP, Bhasin M, Huang S, Kieran MW, Panigrahy D. Chemotherapy-generated cell debris stimulates colon carcinoma tumor growth via osteopontin. FASEB J. 2019 Jan; 33(1):114-125. PMID: 29957058.
    Citations:    Fields:    
  11. Sowalsky AG, Ye H, Bhasin M, Van Allen EM, Loda M, Lis RT, Montaser-Kouhsari L, Calagua C, Ma F, Russo JW, Schaefer RJ, Voznesensky OS, Zhang Z, Bubley GJ, Montgomery B, Mostaghel EA, Nelson PS, Taplin ME, Balk SP. Neoadjuvant-Intensive Androgen Deprivation Therapy Selects for Prostate Tumor Foci with Diverse Subclonal Oncogenic Alterations. Cancer Res. 2018 Aug 15; 78(16):4716-4730. PMID: 29921690.
    Citations:    Fields:    
  12. Bhasin MK, Denninger JW, Huffman JC, Joseph MG, Niles H, Chad-Friedman E, Goldman R, Buczynski-Kelley B, Mahoney BA, Fricchione GL, Dusek JA, Benson H, Zusman RM, Libermann TA. Specific Transcriptome Changes Associated with Blood Pressure Reduction in Hypertensive Patients After Relaxation Response Training. J Altern Complement Med. 2018 May; 24(5):486-504. PMID: 29616846.
    Citations:    Fields:    Translation:HumansCellsCTClinical Trials
  13. Antonello ZA, Hsu N, Bhasin M, Roti G, Joshi M, Van Hummelen P, Ye E, Lo AS, Karumanchi SA, Bryke CR, Nucera C. Vemurafenib-resistance via de novo RBM genes mutations and chromosome 5 aberrations is overcome by combined therapy with palbociclib in thyroid carcinoma with BRAFV600E. Oncotarget. 2017 Oct 17; 8(49):84743-84760. PMID: 29156680.
    Citations: 1     Fields:    
  14. Koppe T, Patchen B, Cheng A, Bhasin M, Vulpe C, Schwartz RE, Moreno-Navarrete JM, Fernandez-Real JM, Pissios P, Fraenkel PG. Nicotinamide N-methyltransferase expression decreases in iron overload, exacerbating toxicity in mouse hepatocytes. Hepatol Commun. 2017 10; 1(8):803-815. PMID: 29404495.
    Citations:    
  15. Jeganathan J, Saraf R, Mahmood F, Pal A, Bhasin MK, Huang T, Mittel A, Knio Z, Simons R, Khabbaz K, Senthilnathan V, Liu D, Sellke F, Matyal R. Mitochondrial Dysfunction in Atrial Tissue of Patients Developing Postoperative Atrial Fibrillation. Ann Thorac Surg. 2017 Nov; 104(5):1547-1555. PMID: 28760472.
    Citations: 1     Fields:    Translation:HumansCells
  16. Herzog R, Kuster L, Becker J, Gluexam T, Pils D, Spittler A, Bhasin MK, Alper SL, Vychytil A, Aufricht C, Kratochwill K. Functional and Transcriptomic Characterization of Peritoneal Immune-Modulation by Addition of Alanyl-Glutamine to Dialysis Fluid. Sci Rep. 2017 07 24; 7(1):6229. PMID: 28740213.
    Citations:    Fields:    
  17. Kuo B, Bhasin M, Jacquart J, Scult MA, Slipp L, Riklin EI, Lepoutre V, Comosa N, Norton BA, Dassatti A, Rosenblum J, Thurler AH, Surjanhata BC, Hasheminejad NN, Kagan L, Slawsby E, Rao SR, Macklin EA, Fricchione GL, Benson H, Libermann TA, Korzenik J, Denninger JW. Correction: Genomic and Clinical Effects Associated with a Relaxation Response Mind-Body Intervention in Patients with Irritable Bowel Syndrome and Inflammatory Bowel Disease. PLoS One. 2017; 12(2):e0172872. PMID: 28222181.
    Citations:    Fields:    
  18. Dusek JA, Otu HH, Wohlhueter AL, Bhasin M, Zerbini LF, Joseph MG, Benson H, Libermann TA. Correction: Genomic Counter-Stress Changes Induced by the Relaxation Response. PLoS One. 2017; 12(2):e0172845. PMID: 28222131.
    Citations:    Fields:    
  19. Bhasin MK, Dusek JA, Chang BH, Joseph MG, Denninger JW, Fricchione GL, Benson H, Libermann TA. Correction: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion and Inflammatory Pathways. PLoS One. 2017; 12(2):e0172873. PMID: 28222196.
    Citations: 1     Fields:    
  20. Thomas C, Henry W, Cuiffo BG, Collmann AY, Marangoni E, Benhamo V, Bhasin MK, Fan C, Fuhrmann L, Baldwin AS, Perou C, Vincent-Salomon A, Toker A, Karnoub AE. Pentraxin-3 is a PI3K signaling target that promotes stem cell-like traits in basal-like breast cancers. Sci Signal. 2017 02 21; 10(467). PMID: 28223411.
    Citations:    Fields:    Translation:HumansCells
  21. Cavalli RC, Cerdeira AS, Pernicone E, Korkes HA, Burke SD, Rajakumar A, Thadhani RI, Roberts DJ, Bhasin M, Karumanchi SA, Kopcow HD. Induced Human Decidual NK-Like Cells Improve Utero-Placental Perfusion in Mice. PLoS One. 2016; 11(10):e0164353. PMID: 27736914.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  22. McKay RR, Werner L, Mostaghel EA, Lis R, Voznesensky O, Zhang Z, Marck BT, Matsumoto AM, Domachevsky L, Zukotynski KA, Bhasin M, Bubley GJ, Montgomery B, Kantoff PW, Balk SP, Taplin ME. A Phase II Trial of Abiraterone Combined with Dutasteride for Men with Metastatic Castration-Resistant Prostate Cancer. Clin Cancer Res. 2017 Feb 15; 23(4):935-945. PMID: 27683182.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  23. Wang X, Solban N, Khanna P, Callea M, Song J, Alsop DC, Pearsall RS, Atkins MB, Mier JW, Signoretti S, Alimzhanov M, Kumar R, Bhasin MK, Bhatt RS. Inhibition of ALK1 signaling with dalantercept combined with VEGFR TKI leads to tumor stasis in renal cell carcinoma. Oncotarget. 2016 Jul 05; 7(27):41857-41869. PMID: 27248821.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  24. Perry CJ, Blake P, Buettner C, Papavassiliou E, Schain AJ, Bhasin MK, Burstein R. Upregulation of inflammatory gene transcripts in periosteum of chronic migraineurs: Implications for extracranial origin of headache. Ann Neurol. 2016 06; 79(6):1000-13. PMID: 27091721.
    Citations: 6     Fields:    Translation:Humans
  25. Rajamani D, Bhasin MK. Identification of key regulators of pancreatic cancer progression through multidimensional systems-level analysis. Genome Med. 2016 05 03; 8(1):38. PMID: 27137215.
    Citations: 6     Fields:    Translation:HumansCells
  26. Bhasin MK, Ndebele K, Bucur O, Yee EU, Otu HH, Plati J, Bullock A, Gu X, Castan E, Zhang P, Najarian R, Muraru MS, Miksad R, Khosravi-Far R, Libermann TA. Meta-analysis of transcriptome data identifies a novel 5-gene pancreatic adenocarcinoma classifier. Oncotarget. 2016 Apr 26; 7(17):23263-81. PMID: 26993610.
    Citations: 9     Fields:    Translation:HumansCells
  27. Tran MT, Zsengeller ZK, Berg AH, Khankin EV, Bhasin MK, Kim W, Clish CB, Stillman IE, Karumanchi SA, Rhee EP, Parikh SM. PGC1a drives NAD biosynthesis linking oxidative metabolism to renal protection. Nature. 2016 Mar 24; 531(7595):528-32. PMID: 26982719.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  28. Rajamani D, Singh PK, Rottmann BG, Singh N, Bhasin MK, Kumar A. Temporal retinal transcriptome and systems biology analysis identifies key pathways and hub genes in Staphylococcus aureus endophthalmitis. Sci Rep. 2016 Feb 11; 6:21502. PMID: 26865111.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  29. Wang F, Kaplan JL, Gold BD, Bhasin MK, Ward NL, Kellermayer R, Kirschner BS, Heyman MB, Dowd SE, Cox SB, Dogan H, Steven B, Ferry GD, Cohen SA, Baldassano RN, Moran CJ, Garnett EA, Drake L, Otu HH, Mirny LA, Libermann TA, Winter HS, Korolev KS. Detecting Microbial Dysbiosis Associated with Pediatric Crohn Disease Despite the High Variability of the Gut Microbiota. Cell Rep. 2016 Feb 02; 14(4):945-955. PMID: 26804920.
    Citations: 5     Fields:    Translation:Humans
  30. Ohguchi H, Hideshima T, Bhasin MK, Gorgun GT, Santo L, Cea M, Samur MK, Mimura N, Suzuki R, Tai YT, Carrasco RD, Raje N, Richardson PG, Munshi NC, Harigae H, Sanda T, Sakai J, Anderson KC. The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival. Nat Commun. 2016 Jan 05; 7:10258. PMID: 26728187.
    Citations: 16     Fields:    Translation:HumansCells
  31. Raof NA, Rajamani D, Chu HC, Gurav A, Johnson JM, LoGerfo FW, Pradhan-Nabzdyk L, Bhasin M. The effects of transfection reagent polyethyleneimine (PEI) and non-targeting control siRNAs on global gene expression in human aortic smooth muscle cells. BMC Genomics. 2016 Jan 05; 17:20. PMID: 26728506.
    Citations: 5     Fields:    Translation:Humans
  32. Cea M, Cagnetta A, Adamia S, Acharya C, Tai YT, Fulciniti M, Ohguchi H, Munshi A, Acharya P, Bhasin MK, Zhong L, Carrasco R, Monacelli F, Ballestrero A, Richardson P, Gobbi M, Lemoli RM, Munshi N, Hideshima T, Nencioni A, Chauhan D, Anderson KC. Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells. Blood. 2016 Mar 03; 127(9):1138-50. PMID: 26675349.
    Citations: 13     Fields:    Translation:HumansCells
  33. de Vasconcellos JF, Laranjeira AB, Leal PC, Bhasin MK, Zenatti PP, Nunes RJ, Yunes RA, Nowill AE, Libermann TA, Zerbini LF, Yunes JA. SB225002 Induces Cell Death and Cell Cycle Arrest in Acute Lymphoblastic Leukemia Cells through the Activation of GLIPR1. PLoS One. 2015; 10(8):e0134783. PMID: 26302043.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  34. Starling RC, Stehlik J, Baran DA, Armstrong B, Stone JR, Ikle D, Morrison Y, Bridges ND, Putheti P, Strom TB, Bhasin M, Guleria I, Chandraker A, Sayegh M, Daly KP, Briscoe DM, Heeger PS. Multicenter Analysis of Immune Biomarkers and Heart Transplant Outcomes: Results of the Clinical Trials in Organ Transplantation-05 Study. Am J Transplant. 2016 Jan; 16(1):121-36. PMID: 26260101.
    Citations: 8     Fields:    Translation:Humans
  35. Owais K, Huang T, Mahmood F, Hubbard J, Saraf R, Bardia A, Khabbaz KR, Li Y, Bhasin M, Sabe AA, Sellke F, Matyal R. Cardiopulmonary Bypass Decreases Activation of the Signal Transducer and Activator of Transcription 3 (STAT3) Pathway in Diabetic Human Myocardium. Ann Thorac Surg. 2015 Nov; 100(5):1636-45; discussion 1645. PMID: 26228595.
    Citations: 4     Fields:    Translation:HumansCells
  36. Studer P, da Silva CG, Revuelta Cervantes JM, Mele A, Csizmadia E, Siracuse JJ, Damrauer SM, Peterson CR, Candinas D, Stroka DM, Ma A, Bhasin M, Ferran C. Significant lethality following liver resection in A20 heterozygous knockout mice uncovers a key role for A20 in liver regeneration. Cell Death Differ. 2015 Dec; 22(12):2068-77. PMID: 25976305.
    Citations: 6     Fields:    Translation:AnimalsCells
  37. Kuo B, Bhasin M, Jacquart J, Scult MA, Slipp L, Riklin EI, Lepoutre V, Comosa N, Norton BA, Dassatti A, Rosenblum J, Thurler AH, Surjanhata BC, Hasheminejad NN, Kagan L, Slawsby E, Rao SR, Macklin EA, Fricchione GL, Benson H, Libermann TA, Korzenik J, Denninger JW. Genomic and clinical effects associated with a relaxation response mind-body intervention in patients with irritable bowel syndrome and inflammatory bowel disease. PLoS One. 2015; 10(4):e0123861. PMID: 25927528.
    Citations: 13     Fields:    Translation:HumansCellsCTClinical Trials
  38. Jedinak A, Curatolo A, Zurakowski D, Dillon S, Bhasin MK, Libermann TA, Roy R, Sachdev M, Loughlin KR, Moses MA. Novel non-invasive biomarkers that distinguish between benign prostate hyperplasia and prostate cancer. BMC Cancer. 2015 Apr 11; 15:259. PMID: 25884438.
    Citations: 8     Fields:    Translation:Humans
  39. de Carvalho Cavalli R, Cerdeira AS, Korkes H, Burke S, Rajakumar A, Bhasin M, Karumanchi SA, Kopcow H. [31-OR]: Modeling an NK cell based immunotherapy for preeclampsia. Pregnancy Hypertens. 2015 Jan; 5(1):15. PMID: 25787381.
    Citations:    
  40. Zhang L, Wang X, Bullock AJ, Callea M, Shah H, Song J, Moreno K, Visentin B, Deutschman D, Alsop DC, Atkins MB, Mier JW, Signoretti S, Bhasin M, Sabbadini RA, Bhatt RS. Anti-S1P Antibody as a Novel Therapeutic Strategy for VEGFR TKI-Resistant Renal Cancer. Clin Cancer Res. 2015 Apr 15; 21(8):1925-1934. PMID: 25589614.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  41. Cuiffo BG, Campagne A, Bell GW, Lembo A, Orso F, Lien EC, Bhasin MK, Raimo M, Hanson SE, Marusyk A, El-Ashry D, Hematti P, Polyak K, Mechta-Grigoriou F, Mariani O, Volinia S, Vincent-Salomon A, Taverna D, Karnoub AE. MSC-regulated microRNAs converge on the transcription factor FOXP2 and promote breast cancer metastasis. Cell Stem Cell. 2014 Dec 04; 15(6):762-74. PMID: 25515522.
    Citations: 34     Fields:    Translation:HumansCells
  42. Dahlke C, Angin M, Müller C, Sharma S, Bhasin MK, Zhuang Y, Addo MM. A Distinct Treg Transcriptome Signature in HIV-1 Elite Controllers Might Contribute to Improved Disease Outcome. AIDS Res Hum Retroviruses. 2014 Oct; 30 Suppl 1:A180. PMID: 25357505.
    Citations:    
  43. Moll HP, Lee A, Minussi DC, da Silva CG, Csizmadia E, Bhasin M, Ferran C. A20 regulates atherogenic interferon (IFN)-? signaling in vascular cells by modulating basal IFNß levels. J Biol Chem. 2014 Nov 07; 289(45):30912-24. PMID: 25217635.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  44. Ramesh N, Massaad MJ, Kumar L, Koduru S, Sasahara Y, Anton I, Bhasin M, Libermann T, Geha R. Binding of the WASP/N-WASP-interacting protein WIP to actin regulates focal adhesion assembly and adhesion. Mol Cell Biol. 2014 Jul; 34(14):2600-10. PMID: 24797074.
    Citations: 5     Fields:    Translation:AnimalsCells
  45. Koulmanda M, Sampathkumar RS, Bhasin M, Qipo A, Fan Z, Singh G, Movahedi B, Duggan M, Chipashvili V, Strom TB. Prevention of nonimmunologic loss of transplanted islets in monkeys. Am J Transplant. 2014 Jul; 14(7):1543-51. PMID: 24913821.
    Citations: 7     Fields:    Translation:Animals
  46. Zerbini LF, Bhasin MK, de Vasconcellos JF, Paccez JD, Gu X, Kung AL, Libermann TA. Computational repositioning and preclinical validation of pentamidine for renal cell cancer. Mol Cancer Ther. 2014 Jul; 13(7):1929-1941. PMID: 24785412.
    Citations: 12     Fields:    Translation:HumansAnimals
  47. Denninger JW, Bhasin M, Huffman J, Niles H, Creager M, Pande R, Liberman T, Fricchione G, Benson H, Zusman R. Clinical and genomic effects of a relaxation response-based mind-body intervention in stage I hypertension. J Altern Complement Med. 2014 May; 20(5):A54. PMID: 24805639.
    Citations:    
  48. Angin M, Sharma S, King M, Murooka TT, Ghebremichael M, Mempel TR, Walker BD, Bhasin MK, Addo MM. HIV-1 infection impairs regulatory T-cell suppressive capacity on a per-cell basis. J Infect Dis. 2014 Sep 15; 210(6):899-903. PMID: 24664171.
    Citations: 12     Fields:    Translation:HumansCells
  49. Arredouani MS, Bhasin MK, Sage DR, Dunn LK, Gill MB, Agnani D, Libermann TA, Fingeroth JD. Analysis of host gene expression changes reveals distinct roles for the cytoplasmic domain of the Epstein-Barr virus receptor/CD21 in B-cell maturation, activation, and initiation of virus infection. J Virol. 2014 May; 88(10):5559-77. PMID: 24600013.
    Citations: 3     Fields:    Translation:HumansCells
  50. Niles H, Mehta DH, Corrigan AA, Bhasin MK, Denninger JW. Functional genomics in the study of mind-body therapies. Ochsner J. 2014; 14(4):681-95. PMID: 25598735.
    Citations: 7     
  51. Black KM, Masuzawa A, Hagberg RC, Khabbaz KR, Trovato ME, Rettagliati VM, Bhasin MK, Dillon ST, Libermann TA, Toumpoulis IK, Levitsky S, McCully JD. Preliminary biomarkers for identification of human ascending thoracic aortic aneurysm. J Am Heart Assoc. 2013 Nov 14; 2(6):e000138. PMID: 24231657.
    Citations: 1     Fields:    Translation:Humans
  52. Skibsted S, Bhasin MK, Aird WC, Shapiro NI. Bench-to-bedside review: future novel diagnostics for sepsis - a systems biology approach. Crit Care. 2013 Oct 04; 17(5):231. PMID: 24093155.
    Citations: 15     Fields:    Translation:Humans
  53. Dillon ST, Bhasin MK, Feng X, Koh DW, Daoud SS. Quantitative proteomic analysis in HCV-induced HCC reveals sets of proteins with potential significance for racial disparity. J Transl Med. 2013 Oct 01; 11:239. PMID: 24283668.
    Citations: 9     Fields:    Translation:HumansCells
  54. Keslar KS, Lin M, Zmijewska AA, Sigdel TK, Tran TQ, Ma L, Bhasin M, Rao P, Ding R, Iklé DN, Mannon RB, Sarwal MM, Strom TB, Reed EF, Heeger PS, Suthanthiran M, Fairchild RL. Multicenter evaluation of a standardized protocol for noninvasive gene expression profiling. Am J Transplant. 2013 Jul; 13(7):1891-7. PMID: 23802725.
    Citations: 12     Fields:    Translation:Humans
  55. Bhasin MK, Dusek JA, Chang BH, Joseph MG, Denninger JW, Fricchione GL, Benson H, Libermann TA. Relaxation response induces temporal transcriptome changes in energy metabolism, insulin secretion and inflammatory pathways. PLoS One. 2013; 8(5):e62817. PMID: 23650531.
    Citations: 56     Fields:    Translation:HumansCells
  56. Reimold FR, Braun N, Zsengellér ZK, Stillman IE, Karumanchi SA, Toka HR, Latus J, Fritz P, Biegger D, Segerer S, Alscher MD, Bhasin MK, Alper SL. Transcriptional patterns in peritoneal tissue of encapsulating peritoneal sclerosis, a complication of chronic peritoneal dialysis. PLoS One. 2013; 8(2):e56389. PMID: 23418565.
    Citations: 4     Fields:    Translation:HumansCells
  57. Friehs I, Cowan DB, Choi YH, Black KM, Barnett R, Bhasin MK, Daly C, Dillon SJ, Libermann TA, McGowan FX, del Nido PJ, Levitsky S, McCully JD. Pressure-overload hypertrophy of the developing heart reveals activation of divergent gene and protein pathways in the left and right ventricular myocardium. Am J Physiol Heart Circ Physiol. 2013 Mar 01; 304(5):H697-708. PMID: 23262132.
    Citations: 4     Fields:    Translation:AnimalsCells
  58. Black KM, Barnett RJ, Bhasin MK, Daly C, Dillon ST, Libermann TA, Levitsky S, McCully JD. Microarray and proteomic analysis of the cardioprotective effects of cold blood cardioplegia in the mature and aged male and female. Physiol Genomics. 2012 Nov 01; 44(21):1027-41. PMID: 22968637.
    Citations: 6     Fields:    Translation:AnimalsCells
  59. Koulmanda M, Bhasin M, Fan Z, Hanidziar D, Goel N, Putheti P, Movahedi B, Libermann TA, Strom TB. Alpha 1-antitrypsin reduces inflammation and enhances mouse pancreatic islet transplant survival. Proc Natl Acad Sci U S A. 2012 Sep 18; 109(38):15443-8. PMID: 22949661.
    Citations: 18     Fields:    Translation:Animals
  60. Carracedo A, Weiss D, Leliaert AK, Bhasin M, de Boer VC, Laurent G, Adams AC, Sundvall M, Song SJ, Ito K, Finley LS, Egia A, Libermann T, Gerhart-Hines Z, Puigserver P, Haigis MC, Maratos-Flier E, Richardson AL, Schafer ZT, Pandolfi PP. A metabolic prosurvival role for PML in breast cancer. J Clin Invest. 2012 Sep; 122(9):3088-100. PMID: 22886304.
    Citations: 68     Fields:    Translation:HumansAnimalsCells
  61. Bhasin M, Huang Z, Pradhan-Nabzdyk L, Malek JY, LoGerfo PJ, Contreras M, Guthrie P, Csizmadia E, Andersen N, Kocher O, Ferran C, LoGerfo FW. Temporal network based analysis of cell specific vein graft transcriptome defines key pathways and hub genes in implantation injury. PLoS One. 2012; 7(6):e39123. PMID: 22720046.
    Citations: 13     Fields:    Translation:AnimalsCells
  62. Koulmanda M, Bhasin M, Awdeh Z, Qipo A, Fan Z, Hanidziar D, Putheti P, Shi H, Csizuadia E, Libermann TA, Strom TB. The role of TNF-a in mice with type 1- and 2- diabetes. PLoS One. 2012; 7(5):e33254. PMID: 22606220.
    Citations: 13     Fields:    Translation:AnimalsCells
  63. Paccez JD, Vasques GJ, Correa RG, Vasconcellos JF, Duncan K, Gu X, Bhasin M, Libermann TA, Zerbini LF. The receptor tyrosine kinase Axl is an essential regulator of prostate cancer proliferation and tumor growth and represents a new therapeutic target. Oncogene. 2013 Feb 07; 32(6):689-98. PMID: 22410775.
    Citations: 35     Fields:    Translation:HumansCells
  64. Wang X, Zhang L, Goldberg SN, Bhasin M, Brown V, Alsop DC, Signoretti S, Mier JW, Atkins MB, Bhatt RS. High dose intermittent sorafenib shows improved efficacy over conventional continuous dose in renal cell carcinoma. J Transl Med. 2011 Dec 21; 9:220. PMID: 22188900.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  65. Yamada Y, Boskovic S, Aoyama A, Murakami T, Putheti P, Smith RN, Ochiai T, Nadazdin O, Koyama I, Boenisch O, Najafian N, Bhasin MK, Colvin RB, Madsen JC, Strom TB, Sachs DH, Benichou G, Cosimi AB, Kawai T. Overcoming memory T-cell responses for induction of delayed tolerance in nonhuman primates. Am J Transplant. 2012 Feb; 12(2):330-40. PMID: 22053723.
    Citations: 39     Fields:    Translation:AnimalsCells
  66. Zerbini LF, Tamura RE, Correa RG, Czibere A, Cordeiro J, Bhasin M, Simabuco FM, Wang Y, Gu X, Li L, Sarkar D, Zhou JR, Fisher PB, Libermann TA. Combinatorial effect of non-steroidal anti-inflammatory drugs and NF-?B inhibitors in ovarian cancer therapy. PLoS One. 2011; 6(9):e24285. PMID: 21931671.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  67. Tran M, Tam D, Bardia A, Bhasin M, Rowe GC, Kher A, Zsengeller ZK, Akhavan-Sharif MR, Khankin EV, Saintgeniez M, David S, Burstein D, Karumanchi SA, Stillman IE, Arany Z, Parikh SM. PGC-1a promotes recovery after acute kidney injury during systemic inflammation in mice. J Clin Invest. 2011 Oct; 121(10):4003-14. PMID: 21881206.
    Citations: 90     Fields:    Translation:AnimalsCells
  68. Yuan L, Sacharidou A, Stratman AN, Le Bras A, Zwiers PJ, Spokes K, Bhasin M, Shih SC, Nagy JA, Molema G, Aird WC, Davis GE, Oettgen P. RhoJ is an endothelial cell-restricted Rho GTPase that mediates vascular morphogenesis and is regulated by the transcription factor ERG. Blood. 2011 Jul 28; 118(4):1145-53. PMID: 21628409.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  69. Zhang L, Bhasin M, Schor-Bardach R, Wang X, Collins MP, Panka D, Putheti P, Signoretti S, Alsop DC, Libermann T, Atkins MB, Mier JW, Goldberg SN, Bhatt RS. Resistance of renal cell carcinoma to sorafenib is mediated by potentially reversible gene expression. PLoS One. 2011 Apr 29; 6(4):e19144. PMID: 21559452.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  70. Damrauer SM, Studer P, da Silva CG, Longo CR, Ramsey HE, Csizmadia E, Shrikhande GV, Scali ST, Libermann TA, Bhasin MK, Ferran C. A20 modulates lipid metabolism and energy production to promote liver regeneration. PLoS One. 2011 Mar 17; 6(3):e17715. PMID: 21437236.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  71. Horst D, Gu X, Bhasin M, Yang Q, Verzi M, Lin D, Joseph M, Zhang X, Chen W, Li YP, Shivdasani RA, Libermann TA. Requirement of the epithelium-specific Ets transcription factor Spdef for mucous gland cell function in the gastric antrum. J Biol Chem. 2010 Nov 05; 285(45):35047-55. PMID: 20801882.
    Citations: 12     Fields:    Translation:Animals
  72. Juengel E, Bhasin M, Libermann T, Barth S, Michaelis M, Cinatl J, Jones J, Hudak L, Jonas D, Blaheta RA. Alterations of the gene expression profile in renal cell carcinoma after treatment with the histone deacetylase-inhibitor valproic acid and interferon-alpha. World J Urol. 2011 Dec; 29(6):779-86. PMID: 20640575.
    Citations: 5     Fields:    Translation:HumansCells
  73. O'Brien KB, Alberich-Jordà M, Yadav N, Kocher O, Diruscio A, Ebralidze A, Levantini E, Sng NJ, Bhasin M, Caron T, Kim D, Steidl U, Huang G, Halmos B, Rodig SJ, Bedford MT, Tenen DG, Kobayashi S. CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells. Development. 2010 Jul; 137(13):2147-56. PMID: 20530543.
    Citations: 25     Fields:    Translation:AnimalsCells
  74. Afkarian M, Bhasin M, Dillon ST, Guerrero MC, Nelson RG, Knowler WC, Thadhani R, Libermann TA. Optimizing a proteomics platform for urine biomarker discovery. Mol Cell Proteomics. 2010 Oct; 9(10):2195-204. PMID: 20511394.
    Citations: 18     Fields:    Translation:Humans
  75. Bhasin M, Yuan L, Keskin DB, Otu HH, Libermann TA, Oettgen P. Bioinformatic identification and characterization of human endothelial cell-restricted genes. BMC Genomics. 2010 May 28; 11:342. PMID: 20509943.
    Citations: 23     Fields:    Translation:HumansCells
  76. Konstantinopoulos PA, Fountzilas E, Goldsmith JD, Bhasin M, Pillay K, Francoeur N, Libermann TA, Gebhardt MC, Spentzos D. Analysis of multiple sarcoma expression datasets: implications for classification, oncogenic pathway activation and chemotherapy resistance. PLoS One. 2010 Apr 01; 5(4):e9747. PMID: 20368975.
    Citations: 7     Fields:    Translation:Humans
  77. Nikolova-Krstevski V, Yuan L, Le Bras A, Vijayaraj P, Kondo M, Gebauer I, Bhasin M, Carman CV, Oettgen P. ERG is required for the differentiation of embryonic stem cells along the endothelial lineage. BMC Dev Biol. 2009 Dec 23; 9:72. PMID: 20030844.
    Citations: 20     Fields:    Translation:AnimalsCells
  78. Arredouani MS, Lu B, Bhasin M, Eljanne M, Yue W, Mosquera JM, Bubley GJ, Li V, Rubin MA, Libermann TA, Sanda MG. Identification of the transcription factor single-minded homologue 2 as a potential biomarker and immunotherapy target in prostate cancer. Clin Cancer Res. 2009 Sep 15; 15(18):5794-802. PMID: 19737960.
    Citations: 53     Fields:    Translation:HumansAnimalsCells
  79. McCully JD, Bhasin MK, Daly C, Guerrero MC, Dillon S, Liberman TA, Cowan DB, Mably JD, McGowan FX, Levitsky S. Transcriptomic and proteomic analysis of global ischemia and cardioprotection in the rabbit heart. Physiol Genomics. 2009 Jul 09; 38(2):125-37. PMID: 19454556.
    Citations: 9     Fields:    Translation:AnimalsCells
  80. Lata S, Bhasin M, Raghava GP. MHCBN 4.0: A database of MHC/TAP binding peptides and T-cell epitopes. BMC Res Notes. 2009 Apr 20; 2:61. PMID: 19379493.
    Citations: 24     Fields:    
  81. Yuan L, Nikolova-Krstevski V, Zhan Y, Kondo M, Bhasin M, Varghese L, Yano K, Carman CV, Aird WC, Oettgen P. Antiinflammatory effects of the ETS factor ERG in endothelial cells are mediated through transcriptional repression of the interleukin-8 gene. Circ Res. 2009 May 08; 104(9):1049-57. PMID: 19359602.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  82. Koulmanda M, Bhasin M, Hoffman L, Fan Z, Qipo A, Shi H, Bonner-Weir S, Putheti P, Degauque N, Libermann TA, Auchincloss H, Flier JS, Strom TB. Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice. Proc Natl Acad Sci U S A. 2008 Oct 21; 105(42):16242-7. PMID: 18852471.
    Citations: 67     Fields:    Translation:AnimalsCells
  83. Haram KM, Peltier HJ, Lu B, Bhasin M, Otu HH, Choy B, Regan M, Libermann TA, Latham GJ, Sanda MG, Arredouani MS. Gene expression profile of mouse prostate tumors reveals dysregulations in major biological processes and identifies potential murine targets for preclinical development of human prostate cancer therapy. Prostate. 2008 Oct 01; 68(14):1517-30. PMID: 18668517.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  84. Dusek JA, Otu HH, Wohlhueter AL, Bhasin M, Zerbini LF, Joseph MG, Benson H, Libermann TA. Genomic counter-stress changes induced by the relaxation response. PLoS One. 2008 Jul 02; 3(7):e2576. PMID: 18596974.
    Citations: 65     Fields:    Translation:HumansCells
  85. Nikolova-Krstevski V, Bhasin M, Otu HH, Libermann T, Oettgen P. Gene expression analysis of embryonic stem cells expressing VE-cadherin (CD144) during endothelial differentiation. BMC Genomics. 2008 May 22; 9:240. PMID: 18498633.
    Citations: 6     Fields:    Translation:AnimalsCells
  86. Nautiyal J, Garg ML, Kumar MS, Khan AA, Thakur JS, Kumar R. Air pollution and cardiovascular health in Mandi-Gobindgarh, Punjab, India - a pilot study. Int J Environ Res Public Health. 2007 Dec; 4(4):268-82. PMID: 18180537.
    Citations:    Fields:    Translation:HumansPHPublic Health
  87. Touma M, Antonini V, Kumar M, Osborn SL, Bobenchik AM, Keskin DB, Connolly JE, Grusby MJ, Reinherz EL, Clayton LK. Functional role for I kappa BNS in T cell cytokine regulation as revealed by targeted gene disruption. J Immunol. 2007 Aug 01; 179(3):1681-92. PMID: 17641034.
    Citations: 12     Fields:    Translation:AnimalsCells
  88. Gu X, Zerbini LF, Otu HH, Bhasin M, Yang Q, Joseph MG, Grall F, Onatunde T, Correa RG, Libermann TA. Reduced PDEF expression increases invasion and expression of mesenchymal genes in prostate cancer cells. Cancer Res. 2007 May 01; 67(9):4219-26. PMID: 17483333.
    Citations: 30     Fields:    Translation:HumansCells
  89. Bhasin M, Lata S, Raghava GP. Searching and mapping of T-cell epitopes, MHC binders, and TAP binders. Methods Mol Biol. 2007; 409:95-112. PMID: 18449994.
    Citations: 1     Fields:    Translation:HumansCells
  90. Bhasin M, Raghava GP. A hybrid approach for predicting promiscuous MHC class I restricted T cell epitopes. J Biosci. 2007 Jan; 32(1):31-42. PMID: 17426378.
    Citations: 33     Fields:    Translation:HumansAnimals
  91. Bhasin M, Lata S, Raghava GP. TAPPred prediction of TAP-binding peptides in antigens. Methods Mol Biol. 2007; 409:381-6. PMID: 18450016.
    Citations: 6     Fields:    Translation:Cells
  92. Lata S, Bhasin M, Raghava GP. Application of machine learning techniques in predicting MHC binders. Methods Mol Biol. 2007; 409:201-15. PMID: 18450002.
    Citations: 17     Fields:    Translation:HumansCells
  93. Sharma VM, Calvo JA, Draheim KM, Cunningham LA, Hermance N, Beverly L, Krishnamoorthy V, Bhasin M, Capobianco AJ, Kelliher MA. Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc. Mol Cell Biol. 2006 Nov; 26(21):8022-31. PMID: 16954387.
    Citations: 112     Fields:    Translation:HumansAnimalsCells
  94. Shank-Calvo JA, Draheim K, Bhasin M, Kelliher MA. p16Ink4a or p19Arf loss contributes to Tal1-induced leukemogenesis in mice. Oncogene. 2006 May 18; 25(21):3023-31. PMID: 16407836.
    Citations: 14     Fields:    Translation:AnimalsCells
  95. Bhasin M, Reinherz EL, Reche PA. Recognition and classification of histones using support vector machine. J Comput Biol. 2006 Jan-Feb; 13(1):102-12. PMID: 16472024.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  96. Bhasin M, Zhang H, Reinherz EL, Reche PA. Prediction of methylated CpGs in DNA sequences using a support vector machine. FEBS Lett. 2005 Aug 15; 579(20):4302-8. PMID: 16051225.
    Citations: 20     Fields:    Translation:HumansCells
  97. Bhasin M, Raghava GP. Pcleavage: an SVM based method for prediction of constitutive proteasome and immunoproteasome cleavage sites in antigenic sequences. Nucleic Acids Res. 2005 Jul 01; 33(Web Server issue):W202-7. PMID: 15988831.
    Citations: 21     Fields:    
  98. Bhasin M, Raghava GP. GPCRsclass: a web tool for the classification of amine type of G-protein-coupled receptors. Nucleic Acids Res. 2005 Jul 01; 33(Web Server issue):W143-7. PMID: 15980444.
    Citations: 13     Fields:    
  99. Kumar M, Bhasin M, Natt NK, Raghava GP. BhairPred: prediction of beta-hairpins in a protein from multiple alignment information using ANN and SVM techniques. Nucleic Acids Res. 2005 Jul 01; 33(Web Server issue):W154-9. PMID: 15988830.
    Citations: 14     Fields:    Translation:Cells
  100. Saha S, Bhasin M, Raghava GP. Bcipep: a database of B-cell epitopes. BMC Genomics. 2005 May 29; 6:79. PMID: 15921533.
    Citations: 51     Fields:    Translation:HumansCells
  101. Bhasin M, Garg A, Raghava GP. PSLpred: prediction of subcellular localization of bacterial proteins. Bioinformatics. 2005 May 15; 21(10):2522-4. PMID: 15699023.
    Citations: 55     Fields:    Translation:Cells
  102. Garg A, Bhasin M, Raghava GP. Support vector machine-based method for subcellular localization of human proteins using amino acid compositions, their order, and similarity search. J Biol Chem. 2005 Apr 15; 280(15):14427-32. PMID: 15647269.
    Citations: 61     Fields:    Translation:HumansCells
  103. Bhasin M, Raghava GP. Prediction of CTL epitopes using QM, SVM and ANN techniques. Vaccine. 2004 Aug 13; 22(23-24):3195-204. PMID: 15297074.
    Citations: 45     Fields:    Translation:HumansCells
  104. Bhasin M, Raghava GP. ESLpred: SVM-based method for subcellular localization of eukaryotic proteins using dipeptide composition and PSI-BLAST. Nucleic Acids Res. 2004 Jul 01; 32(Web Server issue):W414-9. PMID: 15215421.
    Citations: 85     Fields:    Translation:Cells
  105. Bhasin M, Raghava GP. GPCRpred: an SVM-based method for prediction of families and subfamilies of G-protein coupled receptors. Nucleic Acids Res. 2004 Jul 01; 32(Web Server issue):W383-9. PMID: 15215416.
    Citations: 32     Fields:    
  106. Bhasin M, Raghava GP. Classification of nuclear receptors based on amino acid composition and dipeptide composition. J Biol Chem. 2004 May 28; 279(22):23262-6. PMID: 15039428.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  107. Bhasin M, Raghava GP. Analysis and prediction of affinity of TAP binding peptides using cascade SVM. Protein Sci. 2004 Mar; 13(3):596-607. PMID: 14978300.
    Citations: 33     Fields:    Translation:HumansCells
  108. Bhasin M, Raghava GP. SVM based method for predicting HLA-DRB1*0401 binding peptides in an antigen sequence. Bioinformatics. 2004 Feb 12; 20(3):421-3. PMID: 14960470.
    Citations: 38     Fields:    Translation:Cells
  109. Bhasin M, Raghava GP. Prediction of promiscuous and high-affinity mutated MHC binders. Hybrid Hybridomics. 2003 Aug; 22(4):229-34. PMID: 14511568.
    Citations: 4     Fields:    Translation:Cells
  110. Bhasin M, Singh H, Raghava GP. MHCBN: a comprehensive database of MHC binding and non-binding peptides. Bioinformatics. 2003 Mar 22; 19(5):665-6. PMID: 12651731.
    Citations: 57     Fields:    Translation:Cells
  111. Kumar V, Kumar R, Mathur VN, Raina N, Bhasin M, Chakravarty A. Neonatal tetanus mortality in a rural community of Haryana. Indian Pediatr. 1988 Feb; 25(2):167-9. PMID: 3246396.
    Citations: 5     Fields:    Translation:Humans
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.