Harvard Catalyst Profiles

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Nick Lange, Sc.D., D.Sc.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lange N. Editorial: Brain Mediators of the Cannabis-Prodromal Psychosis Connection. J Am Acad Child Adolesc Psychiatry. 2020 May; 59(5):592-594. PMID: 31634567.
  2. Zielinski BA, Prigge MB, Nielsen JA, Froehlich AL, Abildskov TJ, Anderson JS, Fletcher PT, Zygmunt KM, Travers BG, Lange N, Alexander AL, Bigler ED, Lainhart JE. Longitudinal changes in cortical thickness in autism and typical development. Brain. 2014 Jun; 137(Pt 6):1799-812. PMID: 24755274.
    Citations: 59     Fields:    Translation:Humans
  3. Nielsen JA, Zielinski BA, Fletcher PT, Alexander AL, Lange N, Bigler ED, Lainhart JE, Anderson JS. Abnormal lateralization of functional connectivity between language and default mode regions in autism. Mol Autism. 2014 Feb 06; 5(1):8. PMID: 24502324.
    Citations: 10     Fields:    
  4. Travers BG, Bigler ED, Tromp do PM, Adluru N, Froehlich AL, Ennis C, Lange N, Nielsen JA, Prigge MB, Alexander AL, Lainhart JE. Longitudinal processing speed impairments in males with autism and the effects of white matter microstructure. Neuropsychologia. 2014 Jan; 53:137-45. PMID: 24269298.
    Citations: 14     Fields:    Translation:HumansCells
  5. Nielsen JA, Zielinski BA, Fletcher PT, Alexander AL, Lange N, Bigler ED, Lainhart JE, Anderson JS. Multisite functional connectivity MRI classification of autism: ABIDE results. Front Hum Neurosci. 2013; 7:599. PMID: 24093016.
    Citations: 38     
  6. Duffield TC, Trontel HG, Bigler ED, Froehlich A, Prigge MB, Travers B, Green RR, Cariello AN, Cooperrider J, Nielsen J, Alexander A, Anderson J, Fletcher PT, Lange N, Zielinski B, Lainhart J. Neuropsychological investigation of motor impairments in autism. J Clin Exp Neuropsychol. 2013; 35(8):867-81. PMID: 23985036.
    Citations: 10     Fields:    Translation:Humans
  7. Prigge MD, Bigler ED, Fletcher PT, Zielinski BA, Ravichandran C, Anderson J, Froehlich A, Abildskov T, Papadopolous E, Maasberg K, Nielsen JA, Alexander AL, Lange N, Lainhart J. Longitudinal Heschl's gyrus growth during childhood and adolescence in typical development and autism. Autism Res. 2013 Apr; 6(2):78-90. PMID: 23436773.
    Citations: 9     Fields:    Translation:Humans
  8. Zielinski BA, Anderson JS, Froehlich AL, Prigge MB, Nielsen JA, Cooperrider JR, Cariello AN, Fletcher PT, Alexander AL, Lange N, Bigler ED, Lainhart JE. scMRI reveals large-scale brain network abnormalities in autism. PLoS One. 2012; 7(11):e49172. PMID: 23185305.
    Citations: 25     Fields:    Translation:Humans
  9. Lange N. Perspective: Imaging autism. Nature. 2012 Nov 01; 491(7422):S17. PMID: 23136655.
    Citations: 1     Fields:    Translation:Humans
  10. Travers BG, Adluru N, Ennis C, Tromp do PM, Destiche D, Doran S, Bigler ED, Lange N, Lainhart JE, Alexander AL. Diffusion tensor imaging in autism spectrum disorder: a review. Autism Res. 2012 Oct; 5(5):289-313. PMID: 22786754.
    Citations: 110     Fields:    Translation:HumansCells
  11. Lainhart JE, Lange N. Increased neuron number and head size in autism. JAMA. 2011 Nov 09; 306(18):2031-2. PMID: 22068999.
    Citations: 9     Fields:    Translation:HumansCells
  12. Southwick JS, Bigler ED, Froehlich A, DuBray MB, Alexander AL, Lange N, Lainhart JE. Memory functioning in children and adolescents with autism. Neuropsychology. 2011 Nov; 25(6):702-710. PMID: 21843004.
    Citations: 13     Fields:    Translation:Humans
  13. Anderson JS, Nielsen JA, Froehlich AL, DuBray MB, Druzgal TJ, Cariello AN, Cooperrider JR, Zielinski BA, Ravichandran C, Fletcher PT, Alexander AL, Bigler ED, Lange N, Lainhart JE. Functional connectivity magnetic resonance imaging classification of autism. Brain. 2011 Dec; 134(Pt 12):3742-54. PMID: 22006979.
    Citations: 89     Fields:    Translation:Humans
  14. Lange N, Dubray MB, Lee JE, Froimowitz MP, Froehlich A, Adluru N, Wright B, Ravichandran C, Fletcher PT, Bigler ED, Alexander AL, Lainhart JE. Atypical diffusion tensor hemispheric asymmetry in autism. Autism Res. 2010 Dec; 3(6):350-8. PMID: 21182212.
    Citations: 56     Fields:    Translation:HumansCells
  15. Anderson JS, Druzgal TJ, Froehlich A, DuBray MB, Lange N, Alexander AL, Abildskov T, Nielsen JA, Cariello AN, Cooperrider JR, Bigler ED, Lainhart JE. Decreased interhemispheric functional connectivity in autism. Cereb Cortex. 2011 May; 21(5):1134-46. PMID: 20943668.
    Citations: 141     Fields:    Translation:HumansCells
  16. Cataldo AM, McPhie DL, Lange NT, Punzell S, Elmiligy S, Ye NZ, Froimowitz MP, Hassinger LC, Menesale EB, Sargent LW, Logan DJ, Carpenter AE, Cohen BM. Abnormalities in mitochondrial structure in cells from patients with bipolar disorder. Am J Pathol. 2010 Aug; 177(2):575-85. PMID: 20566748.
    Citations: 48     Fields:    Translation:HumansCells
  17. Forester BP, Berlow YA, Harper DG, Jensen JE, Lange N, Froimowitz MP, Ravichandran C, Iosifescu DV, Lukas SE, Renshaw PF, Cohen BM. Age-related changes in brain energetics and phospholipid metabolism. NMR Biomed. 2010 Apr; 23(3):242-50. PMID: 19908224.
    Citations: 14     Fields:    Translation:Humans
  18. Fletcher PT, Whitaker RT, Tao R, DuBray MB, Froehlich A, Ravichandran C, Alexander AL, Bigler ED, Lange N, Lainhart JE. Microstructural connectivity of the arcuate fasciculus in adolescents with high-functioning autism. Neuroimage. 2010 Jul 01; 51(3):1117-25. PMID: 20132894.
    Citations: 75     Fields:    Translation:HumansCells
  19. Pantazopoulos H, Woo TU, Lim MP, Lange N, Berretta S. Extracellular matrix-glial abnormalities in the amygdala and entorhinal cortex of subjects diagnosed with schizophrenia. Arch Gen Psychiatry. 2010 Feb; 67(2):155-66. PMID: 20124115.
    Citations: 63     Fields:    Translation:HumansCells
  20. Bigler ED, Abildskov TJ, Petrie JA, Johnson M, Lange N, Chipman J, Lu J, McMahon W, Lainhart JE. Volumetric and voxel-based morphometry findings in autism subjects with and without macrocephaly. Dev Neuropsychol. 2010; 35(3):278-95. PMID: 20446133.
    Citations: 8     Fields:    Translation:Humans
  21. Lange N, Froimowitz MP, Bigler ED, Lainhart JE. Associations between IQ, total and regional brain volumes, and demography in a large normative sample of healthy children and adolescents. Dev Neuropsychol. 2010; 35(3):296-317. PMID: 20446134.
    Citations: 25     Fields:    Translation:Humans
  22. Adluru N, Hinrichs C, Chung MK, Lee JE, Singh V, Bigler ED, Lange N, Lainhart JE, Alexander AL. Classification in DTI using shapes of white matter tracts. Annu Int Conf IEEE Eng Med Biol Soc. 2009; 2009:2719-22. PMID: 19964040.
    Citations: 8     Fields:    Translation:Humans
  23. Basu AC, Tsai GE, Ma CL, Ehmsen JT, Mustafa AK, Han L, Jiang ZI, Benneyworth MA, Froimowitz MP, Lange N, Snyder SH, Bergeron R, Coyle JT. Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior. Mol Psychiatry. 2009 Jul; 14(7):719-27. PMID: 19065142.
    Citations: 85     Fields:    Translation:AnimalsCells
  24. Sheth A, Berretta S, Lange N, Eichenbaum H. The amygdala modulates neuronal activation in the hippocampus in response to spatial novelty. Hippocampus. 2008; 18(2):169-81. PMID: 17960646.
    Citations: 9     Fields:    Translation:AnimalsCells
  25. Berretta S, Pantazopoulos H, Lange N. Neuron numbers and volume of the amygdala in subjects diagnosed with bipolar disorder or schizophrenia. Biol Psychiatry. 2007 Oct 15; 62(8):884-93. PMID: 17698040.
    Citations: 32     Fields:    Translation:HumansCells
  26. Pantazopoulos H, Lange N, Baldessarini RJ, Berretta S. Parvalbumin neurons in the entorhinal cortex of subjects diagnosed with bipolar disorder or schizophrenia. Biol Psychiatry. 2007 Mar 01; 61(5):640-52. PMID: 16950219.
    Citations: 23     Fields:    Translation:HumansCells
  27. Pantazopoulos H, Lange N, Hassinger L, Berretta S. Subpopulations of neurons expressing parvalbumin in the human amygdala. J Comp Neurol. 2006 Jun 10; 496(5):706-22. PMID: 16615121.
    Citations: 17     Fields:    Translation:HumansCells
  28. Harezlak J, Ryan LM, Giedd JN, Lange N. Individual and population penalized regression splines for accelerated longitudinal designs. Biometrics. 2005 Dec; 61(4):1037-48. PMID: 16401277.
    Citations: 10     Fields:    Translation:Humans
  29. Frazier JA, Chiu S, Breeze JL, Makris N, Lange N, Kennedy DN, Herbert MR, Bent EK, Koneru VK, Dieterich ME, Hodge SM, Rauch SL, Grant PE, Cohen BM, Seidman LJ, Caviness VS, Biederman J. Structural brain magnetic resonance imaging of limbic and thalamic volumes in pediatric bipolar disorder. Am J Psychiatry. 2005 Jul; 162(7):1256-65. PMID: 15994707.
    Citations: 100     Fields:    Translation:Humans
  30. Tsai G, Lane HY, Yang P, Chong MY, Lange N. Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to antipsychotics for the treatment of schizophrenia. Biol Psychiatry. 2004 Mar 01; 55(5):452-6. PMID: 15023571.
    Citations: 64     Fields:    Translation:HumansCTClinical Trials
  31. Lange N, Lake S, Sperling R, Brown J, Routledge C, Albert M, Heckers S. Two macroscopic and microscopic brain imaging studies of human hippocampus in early Alzheimer's disease and schizophrenia research. Stat Med. 2004 Jan 30; 23(2):327-50. PMID: 14716733.
    Citations: 1     Fields:    Translation:HumansCells
  32. Babb SM, Ke Y, Lange N, Kaufman MJ, Renshaw PF, Cohen BM. Oral choline increases choline metabolites in human brain. Psychiatry Res. 2004 Jan 15; 130(1):1-9. PMID: 14972364.
    Citations: 10     Fields:    Translation:Humans
  33. Berretta S, Lange N, Bhattacharyya S, Sebro R, Garces J, Benes FM. Long-term effects of amygdala GABA receptor blockade on specific subpopulations of hippocampal interneurons. Hippocampus. 2004; 14(7):876-94. PMID: 15382257.
    Citations: 25     Fields:    Translation:AnimalsCells
  34. Lange N. What can modern statistics offer imaging neuroscience? Stat Methods Med Res. 2003 Oct; 12(5):447-69. PMID: 14599005.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  35. Herbert MR, Ziegler DA, Deutsch CK, O'Brien LM, Lange N, Bakardjiev A, Hodgson J, Adrien KT, Steele S, Makris N, Kennedy D, Harris GJ, Caviness VS. Dissociations of cerebral cortex, subcortical and cerebral white matter volumes in autistic boys. Brain. 2003 May; 126(Pt 5):1182-92. PMID: 12690057.
    Citations: 108     Fields:    Translation:Humans
  36. Cohen BM, Cherkerzian S, Ma J, Ye N, Wager C, Lange N. Cells in midline thalamus, central amygdala, and nucleus accumbens responding specifically to antipsychotic drugs. Psychopharmacology (Berl). 2003 Jun; 167(4):403-10. PMID: 12709776.
    Citations: 5     Fields:    Translation:Animals
  37. Ma J, Ye N, Lange N, Cohen BM. Dynorphinergic GABA neurons are a target of both typical and atypical antipsychotic drugs in the nucleus accumbens shell, central amygdaloid nucleus and thalamic central medial nucleus. Neuroscience. 2003; 121(4):991-8. PMID: 14580949.
    Citations: 18     Fields:    Translation:AnimalsCells
  38. Herbert MR, Harris GJ, Adrien KT, Ziegler DA, Makris N, Kennedy DN, Lange NT, Chabris CF, Bakardjiev A, Hodgson J, Takeoka M, Tager-Flusberg H, Caviness VS. Abnormal asymmetry in language association cortex in autism. Ann Neurol. 2002 Nov; 52(5):588-96. PMID: 12402256.
    Citations: 73     Fields:    Translation:Humans
  39. Sperling R, Greve D, Dale A, Killiany R, Holmes J, Rosas HD, Cocchiarella A, Firth P, Rosen B, Lake S, Lange N, Routledge C, Albert M. Functional MRI detection of pharmacologically induced memory impairment. Proc Natl Acad Sci U S A. 2002 Jan 08; 99(1):455-60. PMID: 11756667.
    Citations: 54     Fields:    Translation:Humans
  40. Levin JM, Frederick Bde B, Ross MH, Fox JF, von Rosenberg HL, Kaufman MJ, Lange N, Mendelson JH, Cohen BM, Renshaw PF. Influence of baseline hematocrit and hemodilution on BOLD fMRI activation. Magn Reson Imaging. 2001 Oct; 19(8):1055-62. PMID: 11711229.
    Citations: 25     Fields:    Translation:Humans
  41. Henry ME, Kaufman MJ, Lange N, Schmidt ME, Purcell S, Cote J, Perron-Henry DM, Stoddard E, Cohen BM, Renshaw PF. Test-retest reliability of DSC MRI CBV mapping in healthy volunteers. Neuroreport. 2001 Jun 13; 12(8):1567-9. PMID: 11409717.
    Citations: 9     Fields:    Translation:Humans
  42. Benes FM, Lange N. Two-dimensional versus three-dimensional cell counting: a practical perspective. Trends Neurosci. 2001 Jan; 24(1):11-7. PMID: 11163882.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  43. Caviness VS, Makris N, Lange NT, Herbert M, Kennedy DN. Advanced applications of MRI in human brain science. Keio J Med. 2000 Jun; 49(2):66-73. PMID: 10900831.
    Citations:    Fields:    Translation:Humans
  44. Lange N, Strother SC, Anderson JR, Nielsen FA, Holmes AP, Kolenda T, Savoy R, Hansen LK. Plurality and resemblance in fMRI data analysis. Neuroimage. 1999 Sep; 10(3 Pt 1):282-303. PMID: 10458943.
    Citations: 19     Fields:    Translation:Humans
  45. Lange N. Statistical thinking in functional and structural magnetic resonance neuroimaging. Stat Med. 1999 Sep 15-30; 18(17-18):2401-7. PMID: 10474148.
    Citations: 1     Fields:    Translation:Humans
  46. Caviness VS, Lange NT, Makris N, Herbert MR, Kennedy DN. MRI-based brain volumetrics: emergence of a developmental brain science. Brain Dev. 1999 Jul; 21(5):289-95. PMID: 10413014.
    Citations: 15     Fields:    Translation:HumansAnimals
  47. Tsai G, Yang P, Chung LC, Lange N, Coyle JT. D-serine added to antipsychotics for the treatment of schizophrenia. Biol Psychiatry. 1998 Dec 01; 44(11):1081-9. PMID: 9836012.
    Citations: 109     Fields:    Translation:HumansCTClinical Trials
  48. Levin JM, Ross MH, Mendelson JH, Kaufman MJ, Lange N, Maas LC, Mello NK, Cohen BM, Renshaw PF. Reduction in BOLD fMRI response to primary visual stimulation following alcohol ingestion. Psychiatry Res. 1998 Jun 30; 82(3):135-46. PMID: 9754438.
    Citations: 33     Fields:    Translation:HumansCTClinical Trials
  49. Kennedy DN, Lange N, Makris N, Bates J, Meyer J, Caviness VS. Gyri of the human neocortex: an MRI-based analysis of volume and variance. Cereb Cortex. 1998 Jun; 8(4):372-84. PMID: 9651132.
    Citations: 68     Fields:    Translation:Humans
  50. Kaufman MJ, Levin JM, Ross MH, Lange N, Rose SL, Kukes TJ, Mendelson JH, Lukas SE, Cohen BM, Renshaw PF. Cocaine-induced cerebral vasoconstriction detected in humans with magnetic resonance angiography. JAMA. 1998 Feb 04; 279(5):376-80. PMID: 9459471.
    Citations: 26     Fields:    Translation:HumansCTClinical Trials
  51. Lange N, Giedd JN, Castellanos FX, Vaituzis AC, Rapoport JL. Variability of human brain structure size: ages 4-20 years. Psychiatry Res. 1997 Mar 14; 74(1):1-12. PMID: 10710158.
    Citations: 29     Fields:    Translation:Humans
  52. Lange N. Empirical and substantive models, the Bayesian paradigm, and meta-analysis in functional brain imaging. Hum Brain Mapp. 1997; 5(4):259-63. PMID: 20408226.
    Citations:    Fields:    
  53. Castellanos FX, Giedd JN, Marsh WL, Hamburger SD, Vaituzis AC, Dickstein DP, Sarfatti SE, Vauss YC, Snell JW, Lange N, Kaysen D, Krain AL, Ritchie GF, Rajapakse JC, Rapoport JL. Quantitative brain magnetic resonance imaging in attention-deficit hyperactivity disorder. Arch Gen Psychiatry. 1996 Jul; 53(7):607-16. PMID: 8660127.
    Citations: 155     Fields:    Translation:Humans
  54. Giedd JN, Snell JW, Lange N, Rajapakse JC, Casey BJ, Kozuch PL, Vaituzis AC, Vauss YC, Hamburger SD, Kaysen D, Rapoport JL. Quantitative magnetic resonance imaging of human brain development: ages 4-18. Cereb Cortex. 1996 Jul-Aug; 6(4):551-60. PMID: 8670681.
    Citations: 238     Fields:    Translation:HumansCTClinical Trials
  55. Giedd JN, Vaituzis AC, Hamburger SD, Lange N, Rajapakse JC, Kaysen D, Vauss YC, Rapoport JL. Quantitative MRI of the temporal lobe, amygdala, and hippocampus in normal human development: ages 4-18 years. J Comp Neurol. 1996 Mar 04; 366(2):223-30. PMID: 8698883.
    Citations: 187     Fields:    Translation:HumansCTClinical Trials
  56. Lange N. Statistical approaches to human brain mapping by functional magnetic resonance imaging. Stat Med. 1996 Feb 28; 15(4):389-428. PMID: 8668868.
    Citations: 2     Fields:    Translation:Humans
  57. Lange N. Some computational and statistical tools for paired comparisons of digital images. Stat Methods Med Res. 1994; 3(1):23-40. PMID: 8044351.
    Citations: 1     Fields:    Translation:Humans
  58. Cain KC, Lange NT. Approximate case influence for the proportional hazards regression model with censored data. Biometrics. 1984 Jun; 40(2):493-9. PMID: 6386066.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.