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Elena Aikawa, Ph.D., M.D.

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Mentoring
Novel Mechanism of Atherosclerotic Plaque Rupture: Zooming in on the Genesis of Microcalcifications
Summer, 06/26/14 - 08/29/14

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL147095 (AIKAWA, ELENA) Apr 1, 2019 - Mar 31, 2023
    NIH
    New driver of fibrosis and calcification in CAVD
    Role: Principal Investigator
  2. R01HL141917 (LEVINE, ROBERT A) Apr 1, 2018 - Mar 31, 2022
    NIH
    Improving Mitral Compensation In Ischemic Regurgitation
    Role: Co-Principal Investigator
  3. R01HL136431 (AIKAWA, ELENA) Mar 24, 2017 - Feb 28, 2021
    NIH
    Macrophage-derived microcalcificaitons
    Role: Principal Investigator
  4. R01HL114805 (AIKAWA, ELENA) Aug 23, 2012 - Jun 30, 2018
    NIH
    Aortic valve microcalcification
    Role: Principal Investigator
  5. R01HL109506 (LEVINE, ROBERT A) May 15, 2012 - Apr 30, 2017
    NIH
    Improving Mitral Compensation in Ischemic Regurgitation
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Alvandi Z, Nagata Y, Passos LSA, Hashemi Gheinani A, Guerrero JL, Wylie-Sears J, Romero DC, Morris BA, Sullivan SM, Yaghoubian KM, Alvandi A, Adam RM, Aikawa E, Levine RA, Bischoff J. Wnt Site Signaling Inhibitor Secreted Frizzled-Related Protein 3 Protects Mitral Valve Endothelium From Myocardial Infarction-Induced Endothelial-to-Mesenchymal Transition. J Am Heart Assoc. 2022 Apr 05; 11(7):e023695. PMID: 35348006.
    Citations:    Fields:    
  2. Davidson SM, Boulanger CM, Aikawa E, Badimon L, Barile L, Binder CJ, Brisson A, Buzas E, Emanueli C, Jansen F, Katsur M, Lacroix R, Lim SK, Mackman N, Mayr M, Menasché P, Nieuwland R, Sahoo S, Takov K, Thum T, Vader P, Wauben MHM, Witwer K, Sluijter JPG. Methods for the identification and characterization of extracellular vesicles in cardiovascular studies - from exosomes to microvesicles. Cardiovasc Res. 2022 Mar 24. PMID: 35325061.
    Citations:    Fields:    
  3. Gomes NFA, Silva VR, Levine RA, Esteves WAM, de Castro ML, Passos LSA, Dal-Bianco JP, Pantaleão AN, da Silva JLP, Tan TC, Dutra WO, Aikawa E, Hung J, Nunes MCP. Progression of Mitral Regurgitation in Rheumatic Valve Disease: Role of Left Atrial Remodeling. Front Cardiovasc Med. 2022; 9:862382. PMID: 35360029.
    Citations:    
  4. Passos LSA, Jha PK, Becker-Greene D, Blaser MC, Romero D, Lupieri A, Sukhova GK, Libby P, Singh SA, Dutra WO, Aikawa M, Levine RA, Nunes MCP, Aikawa E. Prothymosin Alpha: A Novel Contributor to Estradiol Receptor Alpha-Mediated CD8+ T-Cell Pathogenic Responses and Recognition of Type 1 Collagen in Rheumatic Heart Valve Disease. Circulation. 2022 02 15; 145(7):531-548. PMID: 35157519.
    Citations:    Fields:    Translation:HumansCells
  5. Kraler S, Blaser MC, Aikawa E, Camici GG, Lüscher TF. Calcific aortic valve disease: from molecular and cellular mechanisms to medical therapy. Eur Heart J. 2022 02 12; 43(7):683-697. PMID: 34849696.
    Citations: 2     Fields:    
  6. Buffolo F, Monticone S, Camussi G, Aikawa E. Role of Extracellular Vesicles in the Pathogenesis of Vascular Damage. Hypertension. 2022 Feb 11; HYPERTENSIONAHA12117957. PMID: 35144490.
    Citations:    Fields:    
  7. Rogers MA, Atkins SK, Zheng KH, Singh SA, Chelvanambi S, Pham TH, Kuraoka S, Stroes ESG, Aikawa M, Aikawa E. Lipoprotein(a) Induces Vesicular Cardiovascular Calcification Revealed With Single-Extracellular Vesicle Analysis. Front Cardiovasc Med. 2022; 9:778919. PMID: 35155626.
    Citations:    
  8. Tanaka T, Asano T, Okui T, Kuraoka S, Singh SA, Aikawa M, Aikawa E. Computational Screening Strategy for Drug Repurposing Identified Niclosamide as Inhibitor of Vascular Calcification. Front Cardiovasc Med. 2021; 8:826529. PMID: 35127876.
    Citations:    
  9. Passos LSA, Becker-Greene D, Braulio R, Le TD, Gelape CL, de Almeida LFR, Rocha DPA, Gomes CAP, Esteves WAM, Passaglia LG, Dal-Bianco JP, Levine RA, Aikawa M, Hung J, Dutra WO, Nunes MCP, Aikawa E. Proinflammatory Matrix Metalloproteinase-1 Associates With Mitral Valve Leaflet Disruption Following Percutaneous Mitral Valvuloplasty. Front Cardiovasc Med. 2021; 8:804111. PMID: 35127864.
    Citations:    
  10. Human P, Bezuidenhout D, Aikawa E, Zilla P. Residual Bioprosthetic Valve Immunogenicity: Forgotten, Not Lost. Front Cardiovasc Med. 2021; 8:760635. PMID: 35059444.
    Citations:    
  11. van der Ven CFT, Tibbitt MW, Conde J, van Mil A, Hjortnaes J, Doevendans PA, Sluijter JPG, Aikawa E, Langer RS. Controlled delivery of gold nanoparticle-coupled miRNA therapeutics via an injectable self-healing hydrogel. Nanoscale. 2021 Dec 16; 13(48):20451-20461. PMID: 34817483.
    Citations:    Fields:    Translation:HumansAnimalsCells
  12. Bartoli-Leonard F, Zimmer J, Aikawa E. Innate and adaptive immunity: the understudied driving force of heart valve disease. Cardiovasc Res. 2021 11 22; 117(13):2506-2524. PMID: 34432007.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  13. Iwata H, Osborn EA, Ughi GJ, Murakami K, Goettsch C, Hutcheson JD, Mauskapf A, Mattson PC, Libby P, Singh SA, Matamalas J, Aikawa E, Tearney GJ, Aikawa M, Jaffer FA. Highly Selective PPARa (Peroxisome Proliferator-Activated Receptor a) Agonist Pemafibrate Inhibits Stent Inflammation and Restenosis Assessed by Multimodality Molecular-Microstructural Imaging. J Am Heart Assoc. 2021 10 19; 10(20):e020834. PMID: 34632804.
    Citations:    Fields:    Translation:Animals
  14. Rogers MA, Hutcheson JD, Okui T, Goettsch C, Singh SA, Halu A, Schlotter F, Higashi H, Wang L, Whelan MC, Mlynarchik AK, Daugherty A, Nomura M, Aikawa M, Aikawa E. Dynamin-related protein 1 inhibition reduces hepatic PCSK9 secretion. Cardiovasc Res. 2021 09 28; 117(11):2340-2353. PMID: 33523181.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  15. Zhang H, Chen ZB, Fredman G, Gomez D, Grumbach IM, Huang NF, Nguyen PKP, Ouimet M, Sutton NR, Aikawa E. What Makes a Great Mentor: Interviews With Recipients of the ATVB Mentor of Women Award. Arterioscler Thromb Vasc Biol. 2021 11; 41(11):2641-2647. PMID: 34547925.
    Citations:    Fields:    Translation:Humans
  16. Meerman M, Driessen R, van Engeland NCA, Bergsma I, Steenhuijsen JLG, Kozono D, Aikawa E, Hjortnaes J, Bouten CVC. Radiation Induces Valvular Interstitial Cell Calcific Response in an in vitro Model of Calcific Aortic Valve Disease. Front Cardiovasc Med. 2021; 8:687885. PMID: 34527708.
    Citations:    
  17. Lupieri A, Nagata Y, Passos LSA, Beker-Greene D, Kirkwood KA, Wylie-Sears J, Alvandi Z, Higashi H, Hung JW, Singh SA, Bischoff J, Levine RA, Aikawa E. Integration of Functional Imaging, Cytometry, and Unbiased Proteomics Reveals New Features of Endothelial-to-Mesenchymal Transition in Ischemic Mitral Valve Regurgitation in Human Patients. Front Cardiovasc Med. 2021; 8:688396. PMID: 34458332.
    Citations:    
  18. Rogers MA, Aikawa E. Unbiased omics identifies mechanistic regulators of calcific aortic valve disease. Eur Heart J. 2021 08 07; 42(30):2948-2950. PMID: 34179985.
    Citations:    Fields:    Translation:Humans
  19. Bartoli-Leonard F, Aikawa E. Recapitulating the Complex Pathology of Atherosclerosis: Which Model to Use? Circ Res. 2021 08 06; 129(4):491-493. PMID: 34351800.
    Citations: 1     Fields:    Translation:HumansCells
  20. Hutcheson JD, Schlotter F, Creager MD, Li X, Pham T, Vyas P, Higashi H, Body SC, Aikawa M, Singh SA, Kos L, Aikawa E. Elastogenesis Correlates With Pigment Production in Murine Aortic Valve Leaflets. Front Cardiovasc Med. 2021; 8:678401. PMID: 34239903.
    Citations: 1     
  21. Bartoli-Leonard F, Aikawa E. Old Drugs for an Old Pathology? Drug Repurposing for Calcific Aortic Valve Disease. Circ Res. 2021 04 30; 128(9):1317-1319. PMID: 33914606.
    Citations: 2     Fields:    Translation:Humans
  22. Blaser MC, Kraler S, Lüscher TF, Aikawa E. Multi-Omics Approaches to Define Calcific Aortic Valve Disease Pathogenesis. Circ Res. 2021 04 30; 128(9):1371-1397. PMID: 33914608.
    Citations: 6     Fields:    Translation:HumansCells
  23. Ruiz JL, Hutcheson JD, Cardoso L, Bakhshian Nik A, Condado de Abreu A, Pham T, Buffolo F, Busatto S, Federici S, Ridolfi A, Aikawa M, Bertazzo S, Bergese P, Weinbaum S, Aikawa E. Nanoanalytical analysis of bisphosphonate-driven alterations of microcalcifications using a 3D hydrogel system and in vivo mouse model. Proc Natl Acad Sci U S A. 2021 04 06; 118(14). PMID: 33795519.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  24. Decano JL, Singh SA, Gasparotto Bueno C, Ho Lee L, Halu A, Chelvanambi S, Matamalas JT, Zhang H, Mlynarchik AK, Qiao J, Sharma A, Mukai S, Wang J, Anderson DG, Ozaki CK, Libby P, Aikawa E, Aikawa M. Systems Approach to Discovery of Therapeutic Targets for Vein Graft Disease: PPARa Pivotally Regulates Metabolism, Activation, and Heterogeneity of Macrophages and Lesion Development. Circulation. 2021 06 22; 143(25):2454-2470. PMID: 33821665.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  25. de Freitas RCC, Hirata RDC, Hirata MH, Aikawa E. Circulating Extracellular Vesicles As Biomarkers and Drug Delivery Vehicles in Cardiovascular Diseases. Biomolecules. 2021 03 05; 11(3). PMID: 33808038.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  26. Kraler S, Wenzl FA, Akhmedov A, Blaser MC, Aikawa E, Lüscher TF. ApoA-I mimetics improve aortic stenosis-associated left-ventricular diastolic dysfunction but fail to benefit rabbit models with normal aortic valves. Int J Cardiol. 2021 06 01; 332:159-161. PMID: 33626387.
    Citations:    Fields:    Translation:Animals
  27. Majumdar U, Manivannan S, Basu M, Ueyama Y, Blaser MC, Cameron E, McDermott MR, Lincoln J, Cole SE, Wood S, Aikawa E, Lilly B, Garg V. Nitric oxide prevents aortic valve calcification by S-nitrosylation of USP9X to activate NOTCH signaling. Sci Adv. 2021 Feb; 7(6). PMID: 33547080.
    Citations: 7     Fields:    
  28. Silva VR, Neves EGA, Passos LSA, Cristina de Melo F, Teixeira-Carvalho A, Nassif MCL, Junqueira LL, Aikawa E, Dutra WO, Nunes MCP. Decreased Cytokine Plasma Levels and Changes in T-Cell Activation Are Associated With Hemodynamic Improvement and Clinical Outcomes After Percutaneous Mitral Commissurotomy in Patients With Rheumatic Mitral Stenosis. Front Cardiovasc Med. 2020; 7:604826. PMID: 33614739.
    Citations:    
  29. Passos LSA, Nunes MCP, Aikawa E. Rheumatic Heart Valve Disease Pathophysiology and Underlying Mechanisms. Front Cardiovasc Med. 2020; 7:612716. PMID: 33537348.
    Citations: 5     
  30. Schlotter F, de Freitas RCC, Rogers MA, Blaser MC, Wu PJ, Higashi H, Halu A, Iqbal F, Andraski AB, Rodia CN, Kuraoka S, Wen JR, Creager M, Pham T, Hutcheson JD, Body SC, Kohan AB, Sacks FM, Aikawa M, Singh SA, Aikawa E. ApoC-III is a novel inducer of calcification in human aortic valves. J Biol Chem. 2021 Jan-Jun; 296:100193. PMID: 33334888.
    Citations: 8     Fields:    Translation:HumansCells
  31. Atkins SK, Singh SA, Aikawa E. Calcific Aortic Valve Disease "Omics" Is Timely, But Are We Looking Too Late? JACC Basic Transl Sci. 2020 Dec; 5(12):1178-1180. PMID: 33427821.
    Citations: 2     
  32. Okui T, Iwashita M, Rogers MA, Halu A, Atkins SK, Kuraoka S, Abdelhamid I, Higashi H, Ramsaroop A, Aikawa M, Singh SA, Aikawa E. CROT (Carnitine O-Octanoyltransferase) Is a Novel Contributing Factor in Vascular Calcification via Promoting Fatty Acid Metabolism and Mitochondrial Dysfunction. Arterioscler Thromb Vasc Biol. 2021 02; 41(2):755-768. PMID: 33356393.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  33. Iqbal F, Lupieri A, Aikawa M, Aikawa E. Harnessing Single-Cell RNA Sequencing to Better Understand How Diseased Cells Behave the Way They Do in Cardiovascular Disease. Arterioscler Thromb Vasc Biol. 2021 02; 41(2):585-600. PMID: 33327741.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  34. Passos LSA, Nunes MCP, Zilla P, Yacoub MH, Aikawa E. Raising awareness for rheumatic mitral valve disease. Glob Cardiol Sci Pract. 2020 Nov 30; 2020(2):e202026. PMID: 33426043.
    Citations: 1     
  35. Uiterwijk M, Smits AIPM, van Geemen D, van Klarenbosch B, Dekker S, Cramer MJ, van Rijswijk JW, Lurier EB, Di Luca A, Brugmans MCP, Mes T, Bosman AW, Aikawa E, Gründeman PF, Bouten CVC, Kluin J. In Situ Remodeling Overrules Bioinspired Scaffold Architecture of Supramolecular Elastomeric Tissue-Engineered Heart Valves. JACC Basic Transl Sci. 2020 Dec; 5(12):1187-1206. PMID: 33426376.
    Citations: 4     
  36. Aikawa E, Blaser MC. 2020 Jeffrey M. Hoeg Award Lecture: Calcifying Extracellular Vesicles as Building Blocks of Microcalcifications in Cardiovascular Disorders. Arterioscler Thromb Vasc Biol. 2021 01; 41(1):117-127. PMID: 33115271.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  37. Bartoli-Leonard F, Aikawa E. Heart Valve Disease: Challenges and New Opportunities. Front Cardiovasc Med. 2020; 7:602271. PMID: 33195488.
    Citations: 2     
  38. Rogers MA, Aikawa E. An (Auto)Taxing Effort to Mechanistically Link Obesity and Calcific Aortic Valve Disease. JACC Basic Transl Sci. 2020 Sep; 5(9):898-900. PMID: 33016951.
    Citations: 1     
  39. Rogers MA, Buffolo F, Schlotter F, Atkins SK, Lee LH, Halu A, Blaser MC, Tsolaki E, Higashi H, Luther K, Daaboul G, Bouten CVC, Body SC, Singh SA, Bertazzo S, Libby P, Aikawa M, Aikawa E. Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis. Sci Adv. 2020 09; 6(38). PMID: 32938681.
    Citations: 21     Fields:    
  40. Nunes MCP, Levine RA, Braulio R, Pascoal-Xavier MA, Elmariah S, Gomes NFA, Soares JR, Esteves WAM, Zeng X, Dal-Bianco JP, Passos LSA, Passaglia LG, Ribeiro VT, Gelape CL, Costa PHN, Lodi-Junqueira L, Dutra W, Tan TC, Aikawa E, Hung J. Mitral Regurgitation After Percutaneous Mitral Valvuloplasty: Insights Into Mechanisms and Impact on Clinical Outcomes. JACC Cardiovasc Imaging. 2020 12; 13(12):2513-2526. PMID: 32950446.
    Citations: 2     Fields:    Translation:Humans
  41. Christensen JL, Tan S, Chung HE, Ghosalkar DS, Qureshi R, Chu A, Yu W, Berus J, Shah NR, Wu WC, Chun H, Aikawa E, Choudhary G, Morrison AR. Aortic valve calcification predicts all-cause mortality independent of coronary calcification and severe stenosis. Atherosclerosis. 2020 08; 307:16-20. PMID: 32702536.
    Citations: 2     Fields:    Translation:Humans
  42. Bartoli-Leonard F, Saddic L, Aikawa E. Double-edged sword of ALDH2 mutations: one polymorphism can both benefit and harm the cardiovascular system. Eur Heart J. 2020 07 07; 41(26):2453-2455. PMID: 32585692.
    Citations: 1     Fields:    Translation:Humans
  43. Kawakami R, Katsuki S, Travers R, Romero DC, Becker-Greene D, Passos LSA, Higashi H, Blaser MC, Sukhova GK, Buttigieg J, Kopriva D, Schmidt AM, Anderson DG, Singh SA, Cardoso L, Weinbaum S, Libby P, Aikawa M, Croce K, Aikawa E. S100A9-RAGE Axis Accelerates Formation of Macrophage-Mediated Extracellular Vesicle Microcalcification in Diabetes Mellitus. Arterioscler Thromb Vasc Biol. 2020 08; 40(8):1838-1853. PMID: 32460581.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  44. Passos LSA, Lupieri A, Becker-Greene D, Aikawa E. Innate and adaptive immunity in cardiovascular calcification. Atherosclerosis. 2020 08; 306:59-67. PMID: 32222287.
    Citations: 15     Fields:    Translation:HumansCells
  45. Rogers MA, Aikawa E. Complex association of lipoprotein(a) with aortic stenosis. Heart. 2020 05; 106(10):711-712. PMID: 32086294.
    Citations: 1     Fields:    Translation:Humans
  46. Marsit O, Clavel MA, Côté-Laroche C, Hadjadj S, Bouchard MA, Handschumacher MD, Clisson M, Drolet MC, Boulanger MC, Kim DH, Guerrero JL, Bartko PE, Couet J, Arsenault M, Mathieu P, Pibarot P, Aïkawa E, Bischoff J, Levine RA, Beaudoin J. Attenuated Mitral Leaflet Enlargement Contributes to Functional Mitral Regurgitation After Myocardial Infarction. J Am Coll Cardiol. 2020 02 04; 75(4):395-405. PMID: 32000951.
    Citations: 2     Fields:    Translation:AnimalsCells
  47. Rogers MA, Chen J, Nallamshetty S, Pham T, Goto S, Muehlschlegel JD, Libby P, Aikawa M, Aikawa E, Plutzky J. Retinoids Repress Human Cardiovascular Cell Calcification With Evidence for Distinct Selective Retinoid Modulator Effects. Arterioscler Thromb Vasc Biol. 2020 03; 40(3):656-669. PMID: 31852220.
    Citations: 9     Fields:    Translation:HumansCells
  48. Rogers MA, Aikawa E. MicroRNA Extracellular Vesicle Stowaways in Cell-Cell Communication and Organ Crosstalk. Arterioscler Thromb Vasc Biol. 2019 12; 39(12):2448-2450. PMID: 31770027.
    Citations: 3     Fields:    Translation:Cells
  49. Atkins SK, Aikawa E. Valve under the microscope: shining a light on emerging technologies elucidating disease mechanisms. Heart. 2019 11; 105(21):1610-1611. PMID: 31296591.
    Citations: 1     Fields:    Translation:HumansCells
  50. Zheng KH, Tsimikas S, Pawade T, Kroon J, Jenkins WSA, Doris MK, White AC, Timmers NKLM, Hjortnaes J, Rogers MA, Aikawa E, Arsenault BJ, Witztum JL, Newby DE, Koschinsky ML, Fayad ZA, Stroes ESG, Boekholdt SM, Dweck MR. Lipoprotein(a) and Oxidized Phospholipids Promote Valve Calcification in Patients With Aortic Stenosis. J Am Coll Cardiol. 2019 05 07; 73(17):2150-2162. PMID: 31047003.
    Citations: 43     Fields:    Translation:Humans
  51. Rogers MA, Aikawa E. Cardiovascular calcification: artificial intelligence and big data accelerate mechanistic discovery. Nat Rev Cardiol. 2019 05; 16(5):261-274. PMID: 30531869.
    Citations: 38     Fields:    Translation:Humans
  52. Goto S, Rogers MA, Blaser MC, Higashi H, Lee LH, Schlotter F, Body SC, Aikawa M, Singh SA, Aikawa E. Standardization of Human Calcific Aortic Valve Disease in vitro Modeling Reveals Passage-Dependent Calcification. Front Cardiovasc Med. 2019; 6:49. PMID: 31041314.
    Citations: 11     
  53. Phillippi JA, Aikawa E, Hutcheson J. Editorial: Exploring the Frontiers of Regenerative Cardiovascular Medicine. Front Cardiovasc Med. 2019; 6:13. PMID: 30873414.
    Citations:    
  54. Blaser MC, Aikawa E. Differential miRNA Loading Underpins Dual Harmful and Protective Roles for Extracellular Vesicles in Atherogenesis. Circ Res. 2019 02 15; 124(4):467-469. PMID: 30763209.
    Citations: 9     Fields:    Translation:HumansCells
  55. Hutcheson JD, Goergen CJ, Schoen FJ, Aikawa M, Zilla P, Aikawa E, Gaudette GR. After 50 Years of Heart Transplants: What Does the Next 50 Years Hold for Cardiovascular Medicine? A Perspective From the International Society for Applied Cardiovascular Biology. Front Cardiovasc Med. 2019; 6:8. PMID: 30838213.
    Citations:    
  56. Kovacic JC, Dimmeler S, Harvey RP, Finkel T, Aikawa E, Krenning G, Baker AH. Endothelial to Mesenchymal Transition in Cardiovascular Disease: JACC State-of-the-Art Review. J Am Coll Cardiol. 2019 01 22; 73(2):190-209. PMID: 30654892.
    Citations: 122     Fields:    Translation:HumansAnimalsCells
  57. Nakano T, Katsuki S, Chen M, Decano JL, Halu A, Lee LH, Pestana DVS, Kum AST, Kuromoto RK, Golden WS, Boff MS, Guimaraes GC, Higashi H, Kauffman KJ, Maejima T, Suzuki T, Iwata H, Barabási AL, Aster JC, Anderson DG, Sharma A, Singh SA, Aikawa E, Aikawa M. Uremic Toxin Indoxyl Sulfate Promotes Proinflammatory Macrophage Activation Via the Interplay of OATP2B1 and Dll4-Notch Signaling. Circulation. 2019 01 02; 139(1):78-96. PMID: 30586693.
    Citations: 49     Fields:    Translation:HumansAnimalsCells
  58. Creager MD, Hohl T, Hutcheson JD, Moss AJ, Schlotter F, Blaser MC, Park MA, Lee LH, Singh SA, Alcaide-Corral CJ, Tavares AAS, Newby DE, Kijewski MF, Aikawa M, Di Carli M, Dweck MR, Aikawa E. 18F-Fluoride Signal Amplification Identifies Microcalcifications Associated With Atherosclerotic Plaque Instability in Positron Emission Tomography/Computed Tomography Images. Circ Cardiovasc Imaging. 2019 01; 12(1):e007835. PMID: 30642216.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  59. Blaser MC, Aikawa E. Roles and Regulation of Extracellular Vesicles in Cardiovascular Mineral Metabolism. Front Cardiovasc Med. 2018; 5:187. PMID: 30622949.
    Citations: 33     
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