Harvard Catalyst Profiles

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Toshimi Yoshida, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Sano Y, Yoshida T, Choo MK, Jiménez-Andrade Y, Hill KR, Georgopoulos K, Park JM. Multiorgan Signaling Mobilizes Tumor-Associated Erythroid Cells Expressing Immune Checkpoint Molecules. Mol Cancer Res. 2021 03; 19(3):507-515. PMID: 33234577.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  2. Yoshida T, Hu Y, Zhang Z, Emmanuel AO, Galani K, Muhire B, Snippert HJ, Williams CJ, Tolstorukov MY, Gounari F, Georgopoulos K. Chromatin restriction by the nucleosome remodeler Mi-2ß and functional interplay with lineage-specific transcription regulators control B-cell differentiation. Genes Dev. 2019 07 01; 33(13-14):763-781. PMID: 31123064.
    Citations: 8     Fields:    Translation:AnimalsCells
  3. Murthy V, Tebaldi T, Yoshida T, Erdin S, Calzonetti T, Vijayvargia R, Tripathi T, Kerschbamer E, Seong IS, Quattrone A, Talkowski ME, Gusella JF, Georgopoulos K, MacDonald ME, Biagioli M. Hypomorphic mutation of the mouse Huntington's disease gene orthologue. PLoS Genet. 2019 03; 15(3):e1007765. PMID: 30897080.
    Citations: 6     Fields:    Translation:Animals
  4. Hu Y, Yoshida T, Georgopoulos K. Transcriptional circuits in B cell transformation. Curr Opin Hematol. 2017 Jul; 24(4):345-352. PMID: 28463873.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  5. Hu Y, Zhang Z, Kashiwagi M, Yoshida T, Joshi I, Jena N, Somasundaram R, Emmanuel AO, Sigvardsson M, Fitamant J, El-Bardeesy N, Gounari F, Van Etten RA, Georgopoulos K. Superenhancer reprogramming drives a B-cell-epithelial transition and high-risk leukemia. Genes Dev. 2016 09 01; 30(17):1971-90. PMID: 27664237.
    Citations: 29     Fields:    Translation:AnimalsCells
  6. Perotti EA, Georgopoulos K, Yoshida T. An Ikaros Promoter Element with Dual Epigenetic and Transcriptional Activities. PLoS One. 2015; 10(7):e0131568. PMID: 26135129.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  7. Yoshida T, Georgopoulos K. Ikaros fingers on lymphocyte differentiation. Int J Hematol. 2014 Sep; 100(3):220-9. PMID: 25085254.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  8. Yamada T, Yang Y, Hemberg M, Yoshida T, Cho HY, Murphy JP, Fioravante D, Regehr WG, Gygi SP, Georgopoulos K, Bonni A. Promoter decommissioning by the NuRD chromatin remodeling complex triggers synaptic connectivity in the mammalian brain. Neuron. 2014 Jul 02; 83(1):122-34. PMID: 24991957.
    Citations: 49     Fields:    Translation:HumansAnimalsCells
  9. Joshi I, Yoshida T, Jena N, Qi X, Zhang J, Van Etten RA, Georgopoulos K. Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia. Nat Immunol. 2014 Mar; 15(3):294-304. PMID: 24509510.
    Citations: 78     Fields:    Translation:AnimalsCells
  10. Yoshida T, Georgopoulos K. GATA-3 controls self-renewal in stressed HSCs. Nat Immunol. 2013 Oct; 14(10):1032-3. PMID: 24048133.
    Citations: 2     Fields:    Translation:AnimalsCells
  11. Yoshida T, Landhuis E, Dose M, Hazan I, Zhang J, Naito T, Jackson AF, Wu J, Perotti EA, Kaufmann C, Gounari F, Morgan BA, Georgopoulos K. Transcriptional regulation of the Ikzf1 locus. Blood. 2013 Oct 31; 122(18):3149-59. PMID: 24002445.
    Citations: 22     Fields:    Translation:AnimalsCells
  12. Zhang J, Jackson AF, Naito T, Dose M, Seavitt J, Liu F, Heller EJ, Kashiwagi M, Yoshida T, Gounari F, Petrie HT, Georgopoulos K. Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis. Nat Immunol. 2011 Nov 13; 13(1):86-94. PMID: 22080921.
    Citations: 100     Fields:    Translation:AnimalsCells
  13. Yoshida T, Ng SY, Georgopoulos K. Awakening lineage potential by Ikaros-mediated transcriptional priming. Curr Opin Immunol. 2010 Apr; 22(2):154-60. PMID: 20299195.
    Citations: 27     Fields:    Translation:HumansAnimals
  14. Ng SY, Yoshida T, Zhang J, Georgopoulos K. Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells. Immunity. 2009 Apr 17; 30(4):493-507. PMID: 19345118.
    Citations: 120     Fields:    Translation:AnimalsCells
  15. Yoshida T, Hazan I, Zhang J, Ng SY, Naito T, Snippert HJ, Heller EJ, Qi X, Lawton LN, Williams CJ, Georgopoulos K. The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation. Genes Dev. 2008 May 01; 22(9):1174-89. PMID: 18451107.
    Citations: 98     Fields:    Translation:AnimalsCells
  16. Ng SY, Yoshida T, Georgopoulos K. Ikaros and chromatin regulation in early hematopoiesis. Curr Opin Immunol. 2007 Apr; 19(2):116-22. PMID: 17307348.
    Citations: 25     Fields:    Translation:AnimalsCells
  17. Yoshida T, Ng SY, Zuniga-Pflucker JC, Georgopoulos K. Early hematopoietic lineage restrictions directed by Ikaros. Nat Immunol. 2006 Apr; 7(4):382-91. PMID: 16518393.
    Citations: 118     Fields:    Translation:AnimalsCells
  18. Gomez-del Arco P, Naito T, Seavit J, Yoshida T, Williams C, Georgopoulos K. Zinc-finger proteins: From atomic contact to cellular function. Edited by Iuchi, Shiro, Natalie Kuld (Landes Bioscience (Austin, Texas), ISBN: 978-0-306-48229-8). The Role of the Ikaros Gene Family in Lymphocyte Development. 2004.
  19. Kaufmann C, Yoshida T, Perotti EA, Landhuis E, Wu P, Georgopoulos K. A complex network of regulatory elements in Ikaros and their activity during hemo-lymphopoiesis. EMBO J. 2003 May 01; 22(9):2211-23. PMID: 12727887.
    Citations: 15     Fields:    Translation:AnimalsCells
  20. Moon BG, Yoshida T, Shiiba M, Nakao K, Katsuki M, Takaki S, Takatsu K. Functional dissection of the cytoplasmic subregions of the interleukin-5 receptor alpha chain in growth and immunoglobulin G1 switch recombination of B cells. Immunology. 2001 Mar; 102(3):289-300. PMID: 11298827.
    Citations: 6     Fields:    Translation:AnimalsCells
  21. Hiroi T, Yanagita M, Iijima H, Iwatani K, Yoshida T, Takatsu K, Kiyono H. Deficiency of IL-5 receptor alpha-chain selectively influences the development of the common mucosal immune system independent IgA-producing B-1 cell in mucosa-associated tissues. J Immunol. 1999 Jan 15; 162(2):821-8. PMID: 9916704.
    Citations: 25     Fields:    Translation:AnimalsCells
  22. Sugaya H, Aoki M, Yoshida T, Takatsu K, Yoshimura K. Eosinophilia and intracranial worm recovery in interleukin-5 transgenic and interleukin-5 receptor alpha chain-knockout mice infected with Angiostrongylus cantonensis. Parasitol Res. 1997; 83(6):583-90. PMID: 9211511.
    Citations: 16     Fields:    Translation:Animals
  23. Yoshida T, Ikuta K, Sugaya H, Maki K, Takagi M, Kanazawa H, Sunaga S, Kinashi T, Yoshimura K, Miyazaki J, Takaki S, Takatsu K. Defective B-1 cell development and impaired immunity against Angiostrongylus cantonensis in IL-5R alpha-deficient mice. Immunity. 1996 May; 4(5):483-94. PMID: 8630733.
    Citations: 53     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.