Harvard Catalyst Profiles

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Toshimi Yoshida, PH.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Yoshida T, Hu Y, Zhang Z, Emmanuel AO, Galani K, Muhire B, Snippert HJ, Williams CJ, Tolstorukov MY, Gounari F, Georgopoulos K. Chromatin restriction by the nucleosome remodeler Mi-2ß and functional interplay with lineage-specific transcription regulators control B-cell differentiation. Genes Dev. 2019 May 23. PMID: 31123064.
    Citations:    
  2. Murthy V, Tebaldi T, Yoshida T, Erdin S, Calzonetti T, Vijayvargia R, Tripathi T, Kerschbamer E, Seong IS, Quattrone A, Talkowski ME, Gusella JF, Georgopoulos K, MacDonald ME, Biagioli M. Hypomorphic mutation of the mouse Huntington's disease gene orthologue. PLoS Genet. 2019 03; 15(3):e1007765. PMID: 30897080.
    Citations:    
  3. Hu Y, Yoshida T, Georgopoulos K. Transcriptional circuits in B cell transformation. Curr Opin Hematol. 2017 Jul; 24(4):345-352. PMID: 28463873.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  4. Hu Y, Zhang Z, Kashiwagi M, Yoshida T, Joshi I, Jena N, Somasundaram R, Emmanuel AO, Sigvardsson M, Fitamant J, El-Bardeesy N, Gounari F, Van Etten RA, Georgopoulos K. Superenhancer reprogramming drives a B-cell-epithelial transition and high-risk leukemia. Genes Dev. 2016 09 01; 30(17):1971-90. PMID: 27664237.
    Citations: 11     Fields:    Translation:AnimalsCells
  5. Perotti EA, Georgopoulos K, Yoshida T. An Ikaros Promoter Element with Dual Epigenetic and Transcriptional Activities. PLoS One. 2015; 10(7):e0131568. PMID: 26135129.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  6. Yoshida T, Georgopoulos K. Ikaros fingers on lymphocyte differentiation. Int J Hematol. 2014 Sep; 100(3):220-9. PMID: 25085254.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  7. Yamada T, Yang Y, Hemberg M, Yoshida T, Cho HY, Murphy JP, Fioravante D, Regehr WG, Gygi SP, Georgopoulos K, Bonni A. Promoter decommissioning by the NuRD chromatin remodeling complex triggers synaptic connectivity in the mammalian brain. Neuron. 2014 Jul 02; 83(1):122-34. PMID: 24991957.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  8. Joshi I, Yoshida T, Jena N, Qi X, Zhang J, Van Etten RA, Georgopoulos K. Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia. Nat Immunol. 2014 Mar; 15(3):294-304. PMID: 24509510.
    Citations: 43     Fields:    Translation:AnimalsCells
  9. Yoshida T, Georgopoulos K. GATA-3 controls self-renewal in stressed HSCs. Nat Immunol. 2013 Oct; 14(10):1032-3. PMID: 24048133.
    Citations: 2     Fields:    Translation:AnimalsCells
  10. Yoshida T, Landhuis E, Dose M, Hazan I, Zhang J, Naito T, Jackson AF, Wu J, Perotti EA, Kaufmann C, Gounari F, Morgan BA, Georgopoulos K. Transcriptional regulation of the Ikzf1 locus. Blood. 2013 Oct 31; 122(18):3149-59. PMID: 24002445.
    Citations: 14     Fields:    Translation:AnimalsCells
  11. Zhang J, Jackson AF, Naito T, Dose M, Seavitt J, Liu F, Heller EJ, Kashiwagi M, Yoshida T, Gounari F, Petrie HT, Georgopoulos K. Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis. Nat Immunol. 2011 Nov 13; 13(1):86-94. PMID: 22080921.
    Citations: 76     Fields:    Translation:AnimalsCells
  12. Yoshida T, Ng SY, Georgopoulos K. Awakening lineage potential by Ikaros-mediated transcriptional priming. Curr Opin Immunol. 2010 Apr; 22(2):154-60. PMID: 20299195.
    Citations: 23     Fields:    Translation:HumansAnimals
  13. Ng SY, Yoshida T, Zhang J, Georgopoulos K. Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells. Immunity. 2009 Apr 17; 30(4):493-507. PMID: 19345118.
    Citations: 102     Fields:    Translation:AnimalsCells
  14. Yoshida T, Hazan I, Zhang J, Ng SY, Naito T, Snippert HJ, Heller EJ, Qi X, Lawton LN, Williams CJ, Georgopoulos K. The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation. Genes Dev. 2008 May 01; 22(9):1174-89. PMID: 18451107.
    Citations: 74     Fields:    Translation:AnimalsCells
  15. Ng SY, Yoshida T, Georgopoulos K. Ikaros and chromatin regulation in early hematopoiesis. Curr Opin Immunol. 2007 Apr; 19(2):116-22. PMID: 17307348.
    Citations: 24     Fields:    Translation:AnimalsCells
  16. Yoshida T, Ng SY, Zuniga-Pflucker JC, Georgopoulos K. Early hematopoietic lineage restrictions directed by Ikaros. Nat Immunol. 2006 Apr; 7(4):382-91. PMID: 16518393.
    Citations: 94     Fields:    Translation:AnimalsCells
  17. Gomez-del Arco P, Naito T, Seavit J, Yoshida T, Williams C, Georgopoulos K. Zinc-finger proteins: From atomic contact to cellular function. Edited by Iuchi, Shiro, Natalie Kuld (Landes Bioscience (Austin, Texas), ISBN: 978-0-306-48229-8). The Role of the Ikaros Gene Family in Lymphocyte Development. 2004.
  18. Kaufmann C, Yoshida T, Perotti EA, Landhuis E, Wu P, Georgopoulos K. A complex network of regulatory elements in Ikaros and their activity during hemo-lymphopoiesis. EMBO J. 2003 May 01; 22(9):2211-23. PMID: 12727887.
    Citations: 13     Fields:    Translation:AnimalsCells
  19. Moon BG, Yoshida T, Shiiba M, Nakao K, Katsuki M, Takaki S, Takatsu K. Functional dissection of the cytoplasmic subregions of the interleukin-5 receptor alpha chain in growth and immunoglobulin G1 switch recombination of B cells. Immunology. 2001 Mar; 102(3):289-300. PMID: 11298827.
    Citations: 3     Fields:    Translation:AnimalsCells
  20. Hiroi T, Yanagita M, Iijima H, Iwatani K, Yoshida T, Takatsu K, Kiyono H. Deficiency of IL-5 receptor alpha-chain selectively influences the development of the common mucosal immune system independent IgA-producing B-1 cell in mucosa-associated tissues. J Immunol. 1999 Jan 15; 162(2):821-8. PMID: 9916704.
    Citations: 19     Fields:    Translation:AnimalsCells
  21. Sugaya H, Aoki M, Yoshida T, Takatsu K, Yoshimura K. Eosinophilia and intracranial worm recovery in interleukin-5 transgenic and interleukin-5 receptor alpha chain-knockout mice infected with Angiostrongylus cantonensis. Parasitol Res. 1997; 83(6):583-90. PMID: 9211511.
    Citations: 15     Fields:    Translation:Animals
  22. Yoshida T, Ikuta K, Sugaya H, Maki K, Takagi M, Kanazawa H, Sunaga S, Kinashi T, Yoshimura K, Miyazaki J, Takaki S, Takatsu K. Defective B-1 cell development and impaired immunity against Angiostrongylus cantonensis in IL-5R alpha-deficient mice. Immunity. 1996 May; 4(5):483-94. PMID: 8630733.
    Citations: 46     Fields:    Translation:AnimalsCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.