Harvard Catalyst Profiles

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D. Branch Moody, M.D.

Concepts

This page shows the publications D. Moody has written about Lymphocyte Activation.
Connection Strength

2.239
  1. Structural determination of lipid antigens captured at the CD1d-T-cell receptor interface. Proc Natl Acad Sci U S A. 2017 08 01; 114(31):8348-8353.
    View in: PubMed
    Score: 0.294
  2. CD1 and mycobacterial lipids activate human T cells. Immunol Rev. 2015 Mar; 264(1):138-53.
    View in: PubMed
    Score: 0.250
  3. T-cell activation by lipopeptide antigens. Curr Opin Immunol. 2005 Jun; 17(3):222-9.
    View in: PubMed
    Score: 0.127
  4. CD1d-restricted T cell activation by nonlipidic small molecules. Proc Natl Acad Sci U S A. 2004 Sep 14; 101(37):13578-83.
    View in: PubMed
    Score: 0.121
  5. T cell activation by lipopeptide antigens. Science. 2004 Jan 23; 303(5657):527-31.
    View in: PubMed
    Score: 0.116
  6. Benzofuran sulfonates and small self-lipid antigens activate type II NKT cells via CD1d. Proc Natl Acad Sci U S A. 2021 08 24; 118(34).
    View in: PubMed
    Score: 0.098
  7. CD1a selectively captures endogenous cellular lipids that broadly block T cell response. J Exp Med. 2021 07 05; 218(7).
    View in: PubMed
    Score: 0.096
  8. Lipids hide or step aside for CD1-autoreactive T cell receptors. Curr Opin Immunol. 2018 06; 52:93-99.
    View in: PubMed
    Score: 0.078
  9. CD1b Tetramers Identify T Cells that Recognize Natural and Synthetic Diacylated Sulfoglycolipids from Mycobacterium tuberculosis. Cell Chem Biol. 2018 04 19; 25(4):392-402.e14.
    View in: PubMed
    Score: 0.076
  10. How T cells grasp mycobacterial lipid antigens. Proc Natl Acad Sci U S A. 2017 12 19; 114(51):13312-13314.
    View in: PubMed
    Score: 0.076
  11. CD1b-mycolic acid tetramers demonstrate T-cell fine specificity for mycobacterial lipid tails. Eur J Immunol. 2017 09; 47(9):1525-1534.
    View in: PubMed
    Score: 0.074
  12. Molecular Analysis of Lipid-Reactive Vd1 ?d T Cells Identified by CD1c Tetramers. J Immunol. 2016 Feb 15; 196(4):1933-42.
    View in: PubMed
    Score: 0.066
  13. Human autoreactive T cells recognize CD1b and phospholipids. Proc Natl Acad Sci U S A. 2016 Jan 12; 113(2):380-5.
    View in: PubMed
    Score: 0.066
  14. CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens. Nat Immunol. 2014 Feb; 15(2):177-85.
    View in: PubMed
    Score: 0.057
  15. Cutting Edge: CD1a tetramers and dextramers identify human lipopeptide-specific T cells ex vivo. J Immunol. 2013 Nov 01; 191(9):4499-503.
    View in: PubMed
    Score: 0.057
  16. Lipoproteins are major targets of the polyclonal human T cell response to Mycobacterium tuberculosis. J Immunol. 2013 Jan 01; 190(1):278-84.
    View in: PubMed
    Score: 0.053
  17. CD1b tetramers bind aß T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans. J Exp Med. 2011 Aug 29; 208(9):1741-7.
    View in: PubMed
    Score: 0.049
  18. CD1a-autoreactive T cells are a normal component of the human aß T cell repertoire. Nat Immunol. 2010 Dec; 11(12):1102-9.
    View in: PubMed
    Score: 0.046
  19. CD1c presentation of synthetic glycolipid antigens with foreign alkyl branching motifs. Chem Biol. 2007 Nov; 14(11):1232-42.
    View in: PubMed
    Score: 0.038
  20. TLR gateways to CD1 function. Nat Immunol. 2006 Aug; 7(8):811-7.
    View in: PubMed
    Score: 0.034
  21. Role of lipid trimming and CD1 groove size in cellular antigen presentation. EMBO J. 2006 Jul 12; 25(13):2989-99.
    View in: PubMed
    Score: 0.034
  22. Mycobacterium tuberculosis pks12 produces a novel polyketide presented by CD1c to T cells. J Exp Med. 2004 Dec 20; 200(12):1559-69.
    View in: PubMed
    Score: 0.031
  23. Human ?d T cells recognize CD1b by two distinct mechanisms. Proc Natl Acad Sci U S A. 2020 09 15; 117(37):22944-22952.
    View in: PubMed
    Score: 0.023
  24. ER stress in antigen-presenting cells promotes NKT cell activation through endogenous neutral lipids. EMBO Rep. 2020 06 04; 21(6):e48927.
    View in: PubMed
    Score: 0.022
  25. Total Synthesis of a Mycolic Acid from Mycobacterium tuberculosis. Angew Chem Int Ed Engl. 2020 05 04; 59(19):7555-7560.
    View in: PubMed
    Score: 0.022
  26. CD1b presents self and Borrelia burgdorferi diacylglycerols to human T cells. Eur J Immunol. 2019 05; 49(5):737-746.
    View in: PubMed
    Score: 0.021
  27. CD1--a new paradigm for antigen presentation and T cell activation. Clin Immunol Immunopathol. 1998 Apr; 87(1):8-14.
    View in: PubMed
    Score: 0.019
  28. T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids. Nat Immunol. 2018 04; 19(4):397-406.
    View in: PubMed
    Score: 0.019
  29. A molecular basis of human T cell receptor autoreactivity toward self-phospholipids. Sci Immunol. 2017 10 20; 2(16).
    View in: PubMed
    Score: 0.019
  30. CD1b-autoreactive T cells contribute to hyperlipidemia-induced skin inflammation in mice. J Clin Invest. 2017 Jun 01; 127(6):2339-2352.
    View in: PubMed
    Score: 0.018
  31. T Cell Responses against Mycobacterial Lipids and Proteins Are Poorly Correlated in South African Adolescents. J Immunol. 2015 Nov 15; 195(10):4595-603.
    View in: PubMed
    Score: 0.016
  32. Bee venom processes human skin lipids for presentation by CD1a. J Exp Med. 2015 Feb 09; 212(2):149-63.
    View in: PubMed
    Score: 0.015
  33. Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation. J Immunol. 2014 Aug 15; 193(4):1560-6.
    View in: PubMed
    Score: 0.015
  34. A phase 1 study of adoptive transfer of autologous CD8+ T lymphocytes in patients with acquired immunodeficiency syndrome (AIDS)-related complex or AIDS. Blood. 1993 Apr 15; 81(8):2093-101.
    View in: PubMed
    Score: 0.014
  35. Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity. Nat Med. 2012 Jul; 18(7):1060-8.
    View in: PubMed
    Score: 0.013
  36. CD1-restricted adaptive immune responses to Mycobacteria in human group 1 CD1 transgenic mice. J Exp Med. 2009 Oct 26; 206(11):2497-509.
    View in: PubMed
    Score: 0.011
  37. Mycolyltransferase-mediated glycolipid exchange in Mycobacteria. J Biol Chem. 2008 Oct 24; 283(43):28835-41.
    View in: PubMed
    Score: 0.010
  38. Serum lipids regulate dendritic cell CD1 expression and function. Immunology. 2008 Nov; 125(3):289-301.
    View in: PubMed
    Score: 0.010
  39. IgG regulates the CD1 expression profile and lipid antigen-presenting function in human dendritic cells via FcgammaRIIa. Blood. 2008 May 15; 111(10):5037-46.
    View in: PubMed
    Score: 0.010
  40. Apolipoprotein-mediated pathways of lipid antigen presentation. Nature. 2005 Oct 06; 437(7060):906-10.
    View in: PubMed
    Score: 0.008
  41. Molecular mechanism of lipopeptide presentation by CD1a. Immunity. 2005 Feb; 22(2):209-19.
    View in: PubMed
    Score: 0.008
  42. T-cell responses to CD1-presented lipid antigens in humans with Mycobacterium tuberculosis infection. Infect Immun. 2003 Jun; 71(6):3076-87.
    View in: PubMed
    Score: 0.007
  43. The tyrosine-containing cytoplasmic tail of CD1b is essential for its efficient presentation of bacterial lipid antigens. Immunity. 1998 Mar; 8(3):341-51.
    View in: PubMed
    Score: 0.005
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.