Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

D. Branch Moody, M.D.

Concepts

This page shows the publications D. Moody has written about Antigen Presentation.
Connection Strength

6.253
  1. Four pathways of CD1 antigen presentation to T cells. Curr Opin Immunol. 2017 Jun; 46:127-133.
    View in: PubMed
    Score: 0.434
  2. Donor Unrestricted T Cells: A Shared Human T Cell Response. J Immunol. 2015 Sep 01; 195(5):1927-32.
    View in: PubMed
    Score: 0.380
  3. The CD1 size problem: lipid antigens, ligands, and scaffolds. Cell Mol Life Sci. 2014 Aug; 71(16):3069-79.
    View in: PubMed
    Score: 0.353
  4. CD1a, CD1b, and CD1c in immunity against mycobacteria. Adv Exp Med Biol. 2013; 783:181-97.
    View in: PubMed
    Score: 0.316
  5. Discovery of deoxyceramides and diacylglycerols as CD1b scaffold lipids among diverse groove-blocking lipids of the human CD1 system. Proc Natl Acad Sci U S A. 2011 Nov 29; 108(48):19335-40.
    View in: PubMed
    Score: 0.292
  6. pH-dependent interdomain tethers of CD1b regulate its antigen capture. Immunity. 2008 Jun; 28(6):774-86.
    View in: PubMed
    Score: 0.230
  7. TLR gateways to CD1 function. Nat Immunol. 2006 Aug; 7(8):811-7.
    View in: PubMed
    Score: 0.202
  8. Role of lipid trimming and CD1 groove size in cellular antigen presentation. EMBO J. 2006 Jul 12; 25(13):2989-99.
    View in: PubMed
    Score: 0.201
  9. T-cell recognition of glycolipids presented by CD1 proteins. Glycobiology. 2006 Jul; 16(7):103R-112R.
    View in: PubMed
    Score: 0.198
  10. Mycobacterium tuberculosis regulates CD1 antigen presentation pathways through TLR-2. J Immunol. 2005 Aug 01; 175(3):1758-66.
    View in: PubMed
    Score: 0.189
  11. T cell activation by lipopeptide antigens. Science. 2004 Jan 23; 303(5657):527-31.
    View in: PubMed
    Score: 0.170
  12. Sorting out self and microbial lipid antigens for CD1. Microbes Infect. 2003 Oct; 5(12):1137-48.
    View in: PubMed
    Score: 0.166
  13. Intracellular pathways of CD1 antigen presentation. Nat Rev Immunol. 2003 Jan; 3(1):11-22.
    View in: PubMed
    Score: 0.158
  14. Lipid length controls antigen entry into endosomal and nonendosomal pathways for CD1b presentation. Nat Immunol. 2002 May; 3(5):435-42.
    View in: PubMed
    Score: 0.150
  15. CD1 trafficking: invariant chain gives a new twist to the tale. Immunity. 2001 Dec; 15(6):861-5.
    View in: PubMed
    Score: 0.147
  16. CD36 family members are TCR-independent ligands for CD1 antigen-presenting molecules. Sci Immunol. 2021 06 25; 6(60).
    View in: PubMed
    Score: 0.142
  17. CD1a selectively captures endogenous cellular lipids that broadly block T cell response. J Exp Med. 2021 07 05; 218(7).
    View in: PubMed
    Score: 0.141
  18. The molecular basis of CD1-mediated presentation of lipid antigens. Immunol Rev. 1999 Dec; 172:285-96.
    View in: PubMed
    Score: 0.128
  19. CD1b presents self and Borrelia burgdorferi diacylglycerols to human T cells. Eur J Immunol. 2019 05; 49(5):737-746.
    View in: PubMed
    Score: 0.121
  20. Uptake and processing of glycosylated mycolates for presentation to CD1b-restricted T cells. Immunol Lett. 1999 Jan; 65(1-2):85-91.
    View in: PubMed
    Score: 0.120
  21. Lipids hide or step aside for CD1-autoreactive T cell receptors. Curr Opin Immunol. 2018 06; 52:93-99.
    View in: PubMed
    Score: 0.114
  22. Structural requirements for glycolipid antigen recognition by CD1b-restricted T cells. Science. 1997 Oct 10; 278(5336):283-6.
    View in: PubMed
    Score: 0.110
  23. Donor-unrestricted T cells in the human CD1 system. Immunogenetics. 2016 08; 68(8):577-96.
    View in: PubMed
    Score: 0.101
  24. Molecular Analysis of Lipid-Reactive Vd1 ?d T Cells Identified by CD1c Tetramers. J Immunol. 2016 Feb 15; 196(4):1933-42.
    View in: PubMed
    Score: 0.097
  25. The burgeoning family of unconventional T cells. Nat Immunol. 2015 Nov; 16(11):1114-23.
    View in: PubMed
    Score: 0.096
  26. Lipid and small-molecule display by CD1 and MR1. Nat Rev Immunol. 2015 Oct; 15(10):643-54.
    View in: PubMed
    Score: 0.095
  27. CD1 and mycobacterial lipids activate human T cells. Immunol Rev. 2015 Mar; 264(1):138-53.
    View in: PubMed
    Score: 0.092
  28. aß T cell antigen receptor recognition of CD1a presenting self lipid ligands. Nat Immunol. 2015 Mar; 16(3):258-66.
    View in: PubMed
    Score: 0.091
  29. Bee venom processes human skin lipids for presentation by CD1a. J Exp Med. 2015 Feb 09; 212(2):149-63.
    View in: PubMed
    Score: 0.091
  30. Molecular basis of mycobacterial lipid antigen presentation by CD1c and its recognition by aß T cells. Proc Natl Acad Sci U S A. 2014 Oct 28; 111(43):E4648-57.
    View in: PubMed
    Score: 0.089
  31. Human T cells use CD1 and MR1 to recognize lipids and small molecules. Curr Opin Chem Biol. 2014 Dec; 23:31-8.
    View in: PubMed
    Score: 0.089
  32. CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens. Nat Immunol. 2014 Feb; 15(2):177-85.
    View in: PubMed
    Score: 0.084
  33. CD1c tetramers detect ex vivo T cell responses to processed phosphomycoketide antigens. J Exp Med. 2013 Apr 08; 210(4):729-41.
    View in: PubMed
    Score: 0.080
  34. The evolved functions of CD1 during infection. Curr Opin Immunol. 2009 Aug; 21(4):397-403.
    View in: PubMed
    Score: 0.062
  35. Apolipoprotein-mediated pathways of lipid antigen presentation. Nature. 2005 Oct 06; 437(7060):906-10.
    View in: PubMed
    Score: 0.048
  36. CD1a and CD1c activate intrathyroidal T cells during Graves' disease and Hashimoto's thyroiditis. J Immunol. 2005 Mar 15; 174(6):3773-80.
    View in: PubMed
    Score: 0.046
  37. Molecular mechanism of lipopeptide presentation by CD1a. Immunity. 2005 Feb; 22(2):209-19.
    View in: PubMed
    Score: 0.046
  38. Mycobacterium tuberculosis pks12 produces a novel polyketide presented by CD1c to T cells. J Exp Med. 2004 Dec 20; 200(12):1559-69.
    View in: PubMed
    Score: 0.045
  39. T-cell responses to CD1-presented lipid antigens in humans with Mycobacterium tuberculosis infection. Infect Immun. 2003 Jun; 71(6):3076-87.
    View in: PubMed
    Score: 0.041
  40. Polyisoprenyl glycolipids as targets of CD1-mediated T cell responses. Cell Mol Life Sci. 2001 Sep; 58(10):1461-74.
    View in: PubMed
    Score: 0.036
  41. Benzofuran sulfonates and small self-lipid antigens activate type II NKT cells via CD1d. Proc Natl Acad Sci U S A. 2021 08 24; 118(34).
    View in: PubMed
    Score: 0.036
  42. The A' and F' pockets of human CD1b are both required for optimal presentation of lipid antigens to T cells. J Immunol. 2001 Feb 15; 166(4):2562-70.
    View in: PubMed
    Score: 0.035
  43. Human ?d T cells recognize CD1b by two distinct mechanisms. Proc Natl Acad Sci U S A. 2020 09 15; 117(37):22944-22952.
    View in: PubMed
    Score: 0.034
  44. Glycosyl-phosphatidylinositol reanchoring unmasks distinct antigen-presenting pathways for CD1b and CD1c. J Immunol. 2000 Aug 01; 165(3):1272-7.
    View in: PubMed
    Score: 0.033
  45. A TCR ß-Chain Motif Biases toward Recognition of Human CD1 Proteins. J Immunol. 2019 12 15; 203(12):3395-3406.
    View in: PubMed
    Score: 0.032
  46. Harnessing donor unrestricted T-cells for new vaccines against tuberculosis. Vaccine. 2019 05 21; 37(23):3022-3030.
    View in: PubMed
    Score: 0.031
  47. A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids. Nat Commun. 2019 01 04; 10(1):56.
    View in: PubMed
    Score: 0.030
  48. Mechanisms of lipid antigen presentation by CD1. Crit Rev Immunol. 1999; 19(1):49-63.
    View in: PubMed
    Score: 0.030
  49. CD1--a new paradigm for antigen presentation and T cell activation. Clin Immunol Immunopathol. 1998 Apr; 87(1):8-14.
    View in: PubMed
    Score: 0.028
  50. T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids. Nat Immunol. 2018 04; 19(4):397-406.
    View in: PubMed
    Score: 0.028
  51. The tyrosine-containing cytoplasmic tail of CD1b is essential for its efficient presentation of bacterial lipid antigens. Immunity. 1998 Mar; 8(3):341-51.
    View in: PubMed
    Score: 0.028
  52. The CD1-restricted T-cell response to mycobacteria. Res Immunol. 1996 Oct-Dec; 147(8-9):550-9.
    View in: PubMed
    Score: 0.026
  53. CD1 Antigen Presentation and Autoreactivity in the Pregnant Human Uterus. Am J Reprod Immunol. 2015 Aug; 74(2):126-35.
    View in: PubMed
    Score: 0.023
  54. Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation. J Immunol. 2014 Aug 15; 193(4):1560-6.
    View in: PubMed
    Score: 0.022
  55. CD1-restricted adaptive immune responses to Mycobacteria in human group 1 CD1 transgenic mice. J Exp Med. 2009 Oct 26; 206(11):2497-509.
    View in: PubMed
    Score: 0.016
  56. Serum lipids regulate dendritic cell CD1 expression and function. Immunology. 2008 Nov; 125(3):289-301.
    View in: PubMed
    Score: 0.014
  57. Diversification of CD1 proteins: sampling the lipid content of different cellular compartments. Semin Immunol. 2000 Dec; 12(6):517-25.
    View in: PubMed
    Score: 0.009
  58. Molecular interaction of CD1b with lipoglycan antigens. Immunity. 1998 Mar; 8(3):331-40.
    View in: PubMed
    Score: 0.007
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.