Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

D. Branch Moody, M.D.

Concepts

This page shows the publications D. Moody has written about Animals.
Connection Strength

0.406
  1. Mycobacterium tuberculosis releases an antacid that remodels phagosomes. Nat Chem Biol. 2019 09; 15(9):889-899.
    View in: PubMed
    Score: 0.020
  2. Lipids hide or step aside for CD1-autoreactive T cell receptors. Curr Opin Immunol. 2018 06; 52:93-99.
    View in: PubMed
    Score: 0.019
  3. Four pathways of CD1 antigen presentation to T cells. Curr Opin Immunol. 2017 Jun; 46:127-133.
    View in: PubMed
    Score: 0.018
  4. Structural determination of lipid antigens captured at the CD1d-T-cell receptor interface. Proc Natl Acad Sci U S A. 2017 08 01; 114(31):8348-8353.
    View in: PubMed
    Score: 0.018
  5. The burgeoning family of unconventional T cells. Nat Immunol. 2015 Nov; 16(11):1114-23.
    View in: PubMed
    Score: 0.016
  6. In vivo biosynthesis of terpene nucleosides provides unique chemical markers of Mycobacterium tuberculosis infection. Chem Biol. 2015 Apr 23; 22(4):516-526.
    View in: PubMed
    Score: 0.015
  7. Lipidomic analysis links mycobactin synthase K to iron uptake and virulence in M. tuberculosis. PLoS Pathog. 2015 Mar; 11(3):e1004792.
    View in: PubMed
    Score: 0.015
  8. CD1 and mycobacterial lipids activate human T cells. Immunol Rev. 2015 Mar; 264(1):138-53.
    View in: PubMed
    Score: 0.015
  9. Human T cells use CD1 and MR1 to recognize lipids and small molecules. Curr Opin Chem Biol. 2014 Dec; 23:31-8.
    View in: PubMed
    Score: 0.015
  10. The CD1 size problem: lipid antigens, ligands, and scaffolds. Cell Mol Life Sci. 2014 Aug; 71(16):3069-79.
    View in: PubMed
    Score: 0.014
  11. CD1a, CD1b, and CD1c in immunity against mycobacteria. Adv Exp Med Biol. 2013; 783:181-97.
    View in: PubMed
    Score: 0.013
  12. A comparative lipidomics platform for chemotaxonomic analysis of Mycobacterium tuberculosis. Chem Biol. 2011 Dec 23; 18(12):1537-49.
    View in: PubMed
    Score: 0.012
  13. Mincle is a long sought receptor for mycobacterial cord factor. J Exp Med. 2009 Dec 21; 206(13):2865-8.
    View in: PubMed
    Score: 0.010
  14. The evolved functions of CD1 during infection. Curr Opin Immunol. 2009 Aug; 21(4):397-403.
    View in: PubMed
    Score: 0.010
  15. CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids. J Exp Med. 2009 Jun 08; 206(6):1409-22.
    View in: PubMed
    Score: 0.010
  16. Immunology: how a T cell sees sugar. Nature. 2007 Jul 05; 448(7149):36-7.
    View in: PubMed
    Score: 0.009
  17. TLR gateways to CD1 function. Nat Immunol. 2006 Aug; 7(8):811-7.
    View in: PubMed
    Score: 0.008
  18. T-cell recognition of glycolipids presented by CD1 proteins. Glycobiology. 2006 Jul; 16(7):103R-112R.
    View in: PubMed
    Score: 0.008
  19. The surprising diversity of lipid antigens for CD1-restricted T cells. Adv Immunol. 2006; 89:87-139.
    View in: PubMed
    Score: 0.008
  20. Mycobacterium tuberculosis regulates CD1 antigen presentation pathways through TLR-2. J Immunol. 2005 Aug 01; 175(3):1758-66.
    View in: PubMed
    Score: 0.008
  21. T-cell activation by lipopeptide antigens. Curr Opin Immunol. 2005 Jun; 17(3):222-9.
    View in: PubMed
    Score: 0.008
  22. Sorting out self and microbial lipid antigens for CD1. Microbes Infect. 2003 Oct; 5(12):1137-48.
    View in: PubMed
    Score: 0.007
  23. Intracellular pathways of CD1 antigen presentation. Nat Rev Immunol. 2003 Jan; 3(1):11-22.
    View in: PubMed
    Score: 0.006
  24. CD1 trafficking: invariant chain gives a new twist to the tale. Immunity. 2001 Dec; 15(6):861-5.
    View in: PubMed
    Score: 0.006
  25. Glycolipid targets of CD1-mediated T-cell responses. Immunology. 2001 Nov; 104(3):243-51.
    View in: PubMed
    Score: 0.006
  26. Polyisoprenyl glycolipids as targets of CD1-mediated T cell responses. Cell Mol Life Sci. 2001 Sep; 58(10):1461-74.
    View in: PubMed
    Score: 0.006
  27. Heterologous Production of 1-Tuberculosinyladenosine in Mycobacterium kansasii Models Pathoevolution towards the Transcellular Lifestyle of Mycobacterium tuberculosis. mBio. 2020 10 20; 11(5).
    View in: PubMed
    Score: 0.006
  28. CD1b-mediated T cell recognition of a glycolipid antigen generated from mycobacterial lipid and host carbohydrate during infection. J Exp Med. 2000 Oct 02; 192(7):965-76.
    View in: PubMed
    Score: 0.006
  29. Asymmetric Total Synthesis of Mycobacterial Diacyl Trehaloses Demonstrates a Role for Lipid Structure in Immunogenicity. ACS Chem Biol. 2020 07 17; 15(7):1835-1841.
    View in: PubMed
    Score: 0.005
  30. The molecular basis of CD1-mediated presentation of lipid antigens. Immunol Rev. 1999 Dec; 172:285-96.
    View in: PubMed
    Score: 0.005
  31. Harnessing donor unrestricted T-cells for new vaccines against tuberculosis. Vaccine. 2019 05 21; 37(23):3022-3030.
    View in: PubMed
    Score: 0.005
  32. Discovery of Salmonella trehalose phospholipids reveals functional convergence with mycobacteria. J Exp Med. 2019 04 01; 216(4):757-771.
    View in: PubMed
    Score: 0.005
  33. A molecular basis of human T cell receptor autoreactivity toward self-phospholipids. Sci Immunol. 2017 10 20; 2(16).
    View in: PubMed
    Score: 0.004
  34. A Macrophage Response to Mycobacterium leprae Phenolic Glycolipid Initiates Nerve Damage in Leprosy. Cell. 2017 Aug 24; 170(5):973-985.e10.
    View in: PubMed
    Score: 0.004
  35. CD1b-autoreactive T cells contribute to hyperlipidemia-induced skin inflammation in mice. J Clin Invest. 2017 Jun 01; 127(6):2339-2352.
    View in: PubMed
    Score: 0.004
  36. The CD1-restricted T-cell response to mycobacteria. Res Immunol. 1996 Oct-Dec; 147(8-9):550-9.
    View in: PubMed
    Score: 0.004
  37. Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase. Sci Transl Med. 2016 Feb 10; 8(325):325ra18.
    View in: PubMed
    Score: 0.004
  38. Mycobacterial Metabolic Syndrome: LprG and Rv1410 Regulate Triacylglyceride Levels, Growth Rate and Virulence in Mycobacterium tuberculosis. PLoS Pathog. 2016 Jan; 12(1):e1005351.
    View in: PubMed
    Score: 0.004
  39. Elevated and cross-responsive CD1a-reactive T cells in bee and wasp venom allergic individuals. Eur J Immunol. 2016 Jan; 46(1):242-52.
    View in: PubMed
    Score: 0.004
  40. Biomarkers for Tuberculosis Based on Secreted, Species-Specific, Bacterial Small Molecules. J Infect Dis. 2015 Dec 01; 212(11):1827-34.
    View in: PubMed
    Score: 0.004
  41. Bee venom processes human skin lipids for presentation by CD1a. J Exp Med. 2015 Feb 09; 212(2):149-63.
    View in: PubMed
    Score: 0.004
  42. Interleukin-2 transfected prostate cancer cells generate a local antitumor effect in vivo. Prostate. 1994 May; 24(5):244-51.
    View in: PubMed
    Score: 0.004
  43. The bovine CD1D gene has an unusual gene structure and is expressed but cannot present a-galactosylceramide with a C26 fatty acid. Int Immunol. 2013 Feb; 25(2):91-8.
    View in: PubMed
    Score: 0.003
  44. Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity. Nat Med. 2012 Jul; 18(7):1060-8.
    View in: PubMed
    Score: 0.003
  45. Saposins utilize two strategies for lipid transfer and CD1 antigen presentation. Proc Natl Acad Sci U S A. 2012 Mar 20; 109(12):4357-64.
    View in: PubMed
    Score: 0.003
  46. Analysis of the CD1 antigen presenting system in humanized SCID mice. PLoS One. 2011; 6(6):e21701.
    View in: PubMed
    Score: 0.003
  47. Low cross-reactivity of T-cell responses against lipids from Mycobacterium bovis and M. avium paratuberculosis during natural infection. Eur J Immunol. 2009 Nov; 39(11):3031-41.
    View in: PubMed
    Score: 0.003
  48. Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition. Proc Natl Acad Sci U S A. 2009 Nov 03; 106(44):18792-7.
    View in: PubMed
    Score: 0.003
  49. CD1-restricted adaptive immune responses to Mycobacteria in human group 1 CD1 transgenic mice. J Exp Med. 2009 Oct 26; 206(11):2497-509.
    View in: PubMed
    Score: 0.003
  50. Mycolyltransferase-mediated glycolipid exchange in Mycobacteria. J Biol Chem. 2008 Oct 24; 283(43):28835-41.
    View in: PubMed
    Score: 0.002
  51. Loss of the acyl-CoA binding protein (Acbp) results in fatty acid metabolism abnormalities in mouse hair and skin. J Invest Dermatol. 2007 Jan; 127(1):16-23.
    View in: PubMed
    Score: 0.002
  52. Apolipoprotein-mediated pathways of lipid antigen presentation. Nature. 2005 Oct 06; 437(7060):906-10.
    View in: PubMed
    Score: 0.002
  53. Structural features of the acyl chain determine self-phospholipid antigen recognition by a CD1d-restricted invariant NKT (iNKT) cell. J Biol Chem. 2003 Nov 28; 278(48):47508-15.
    View in: PubMed
    Score: 0.002
  54. Metabolism of capsaicin by cytochrome P450 produces novel dehydrogenated metabolites and decreases cytotoxicity to lung and liver cells. Chem Res Toxicol. 2003 Mar; 16(3):336-49.
    View in: PubMed
    Score: 0.002
  55. The A' and F' pockets of human CD1b are both required for optimal presentation of lipid antigens to T cells. J Immunol. 2001 Feb 15; 166(4):2562-70.
    View in: PubMed
    Score: 0.001
  56. Diversification of CD1 proteins: sampling the lipid content of different cellular compartments. Semin Immunol. 2000 Dec; 12(6):517-25.
    View in: PubMed
    Score: 0.001
  57. Mechanisms of lipid antigen presentation by CD1. Crit Rev Immunol. 1999; 19(1):49-63.
    View in: PubMed
    Score: 0.001
  58. CD1--a new paradigm for antigen presentation and T cell activation. Clin Immunol Immunopathol. 1998 Apr; 87(1):8-14.
    View in: PubMed
    Score: 0.001
  59. Human CD4+ and CD8+ T lymphocytes are both cytotoxic to Toxoplasma gondii-infected cells. Infect Immun. 1996 Jan; 64(1):176-81.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.