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D. Branch Moody, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Mishra VK, Buter J, Blevins MS, Witte MD, Van Rhijn I, Moody DB, Brodbelt JS, Minnaard AJ. Total Synthesis of an Immunogenic Trehalose Phospholipid from Salmonella Typhi and Elucidation of Its sn-Regiochemistry by Mass Spectrometry. Org Lett. 2019 Jul 05; 21(13):5126-5131. PMID: 31247773.
    Citations:    
  2. Joosten SA, Ottenhoff THM, Lewinsohn DM, Hoft DF, Moody DB, Seshadri C. Harnessing donor unrestricted T-cells for new vaccines against tuberculosis. Vaccine. 2019 May 21; 37(23):3022-3030. PMID: 31040086.
    Citations:    
  3. Reinink P, Souter MNT, Cheng TY, van Gorkom T, Lenz S, Kubler-Kielb J, Strle K, Kremer K, Thijsen SFT, Steere AC, Godfrey DI, Pellicci DG, Moody DB, Van Rhijn I. CD1b presents self and Borrelia burgdorferi diacylglycerols to human T cells. Eur J Immunol. 2019 May; 49(5):737-746. PMID: 30854633.
    Citations:    
  4. Reinink P, Buter J, Mishra VK, Ishikawa E, Cheng TY, Willemsen PTJ, Porwollik S, Brennan PJ, Heinz E, Mayfield JA, Dougan G, van Els CA, Cerundolo V, Napolitani G, Yamasaki S, Minnaard AJ, McClelland M, Moody DB, Van Rhijn I. Discovery of Salmonella trehalose phospholipids reveals functional convergence with mycobacteria. J Exp Med. 2019 Apr 01; 216(4):757-771. PMID: 30804000.
    Citations:    
  5. Shahine A, Reinink P, Reijneveld JF, Gras S, Holzheimer M, Cheng TY, Minnaard AJ, Altman JD, Lenz S, Prandi J, Kubler-Kielb J, Moody DB, Rossjohn J, Van Rhijn I. A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids. Nat Commun. 2019 01 04; 10(1):56. PMID: 30610190.
    Citations:    Fields:    
  6. Puffal J, Mayfield JA, Moody DB, Morita YS. Demethylmenaquinone Methyl Transferase Is a Membrane Domain-Associated Protein Essential for Menaquinone Homeostasis in Mycobacterium smegmatis. Front Microbiol. 2018; 9:3145. PMID: 30619211.
    Citations:    
  7. Cotton RN, Shahine A, Rossjohn J, Moody DB. Lipids hide or step aside for CD1-autoreactive T cell receptors. Curr Opin Immunol. 2018 06; 52:93-99. PMID: 29738961.
    Citations: 1     Fields:    
  8. Lee-Sarwar K, Kelly RS, Lasky-Su J, Moody DB, Mola AR, Cheng TY, Comstock LE, Zeiger RS, O'Connor GT, Sandel MT, Bacharier LB, Beigelman A, Laranjo N, Gold DR, Bunyavanich S, Savage JH, Weiss ST, Brennan PJ, Litonjua AA. Intestinal microbial-derived sphingolipids are inversely associated with childhood food allergy. J Allergy Clin Immunol. 2018 Jul; 142(1):335-338.e9. PMID: 29729303.
    Citations:    Fields:    
  9. Wun KS, Reijneveld JF, Cheng TY, Ladell K, Uldrich AP, Le Nours J, Miners KL, McLaren JE, Grant EJ, Haigh OL, Watkins TS, Suliman S, Iwany S, Jimenez J, Calderon R, Tamara KL, Leon SR, Murray MB, Mayfield JA, Altman JD, Purcell AW, Miles JJ, Godfrey DI, Gras S, Price DA, Van Rhijn I, Moody DB, Rossjohn J. T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids. Nat Immunol. 2018 04; 19(4):397-406. PMID: 29531339.
    Citations: 3     Fields:    
  10. Carette X, Platig J, Young DC, Helmel M, Young AT, Wang Z, Potluri LP, Moody CS, Zeng J, Prisic S, Paulson JN, Muntel J, Madduri AVR, Velarde J, Mayfield JA, Locher C, Wang T, Quackenbush J, Rhee KY, Moody DB, Steen H, Husson RN. Multisystem Analysis of Mycobacterium tuberculosis Reveals Kinase-Dependent Remodeling of the Pathogen-Environment Interface. MBio. 2018 03 06; 9(2). PMID: 29511081.
    Citations:    Fields:    Translation:Cells
  11. James CA, Yu KKQ, Gilleron M, Prandi J, Yedulla VR, Moleda ZZ, Diamanti E, Khan M, Aggarwal VK, Reijneveld JF, Reinink P, Lenz S, Emerson RO, Scriba TJ, Souter MNT, Godfrey DI, Pellicci DG, Moody DB, Minnaard AJ, Seshadri C, Van Rhijn I. CD1b Tetramers Identify T Cells that Recognize Natural and Synthetic Diacylated Sulfoglycolipids from Mycobacterium tuberculosis. Cell Chem Biol. 2018 04 19; 25(4):392-402.e14. PMID: 29398561.
    Citations: 2     Fields:    
  12. Moody DB. How T cells grasp mycobacterial lipid antigens. Proc Natl Acad Sci U S A. 2017 12 19; 114(51):13312-13314. PMID: 29217637.
    Citations:    Fields:    Translation:Cells
  13. Lehmann J, Cheng TY, Aggarwal A, Park AS, Zeiler E, Raju RM, Akopian T, Kandror O, Sacchettini JC, Moody DB, Rubin EJ, Sieber SA. An Antibacterial ß-Lactone Kills Mycobacterium tuberculosis by Disrupting Mycolic Acid Biosynthesis. Angew Chem Int Ed Engl. 2018 01 02; 57(1):348-353. PMID: 29067779.
    Citations: 1     Fields:    
  14. Moody DB, Suliman S. CD1: From Molecules to Diseases. F1000Res. 2017; 6:1909. PMID: 29152228.
    Citations:    
  15. Shahine A, Van Rhijn I, Cheng TY, Iwany S, Gras S, Moody DB, Rossjohn J. A molecular basis of human T cell receptor autoreactivity toward self-phospholipids. Sci Immunol. 2017 10 20; 2(16). PMID: 29054999.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  16. Madigan CA, Cambier CJ, Kelly-Scumpia KM, Scumpia PO, Cheng TY, Zailaa J, Bloom BR, Moody DB, Smale ST, Sagasti A, Modlin RL, Ramakrishnan L. A Macrophage Response to Mycobacterium leprae Phenolic Glycolipid Initiates Nerve Damage in Leprosy. Cell. 2017 Aug 24; 170(5):973-985.e10. PMID: 28841420.
    Citations: 7     Fields:    Translation:AnimalsCells
  17. Van Rhijn I, Iwany SK, Fodran P, Cheng TY, Gapin L, Minnaard AJ, Moody DB. CD1b-mycolic acid tetramers demonstrate T-cell fine specificity for mycobacterial lipid tails. Eur J Immunol. 2017 09; 47(9):1525-1534. PMID: 28665555.
    Citations: 5     Fields:    Translation:HumansCells
  18. Moody DB, Cotton RN. Four pathways of CD1 antigen presentation to T cells. Curr Opin Immunol. 2017 Jun; 46:127-133. PMID: 28756303.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  19. Brennan PJ, Cheng TY, Pellicci DG, Watts GFM, Veerapen N, Young DC, Rossjohn J, Besra GS, Godfrey DI, Brenner MB, Moody DB. Structural determination of lipid antigens captured at the CD1d-T-cell receptor interface. Proc Natl Acad Sci U S A. 2017 08 01; 114(31):8348-8353. PMID: 28716901.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  20. Bagchi S, He Y, Zhang H, Cao L, Van Rhijn I, Moody DB, Gudjonsson JE, Wang CR. CD1b-autoreactive T cells contribute to hyperlipidemia-induced skin inflammation in mice. J Clin Invest. 2017 Jun 01; 127(6):2339-2352. PMID: 28463230.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  21. Cheng JM, Liu L, Pellicci DG, Reddiex SJ, Cotton RN, Cheng TY, Young DC, Van Rhijn I, Moody DB, Rossjohn J, Fairlie DP, Godfrey DI, Williams SJ. Total Synthesis of Mycobacterium tuberculosis Dideoxymycobactin-838 and Stereoisomers: Diverse CD1a-Restricted T Cells Display a Common Hierarchy of Lipopeptide Recognition. Chemistry. 2017 Jan 31; 23(7):1694-1701. PMID: 27925318.
    Citations: 1     Fields:    Translation:HumansCells
  22. Jia Q, Tan C, Wang J, Zhang XQ, Zhu J, Luo H, Yang J, Westcott S, Broughton S, Moody D, Li C. Marker development using SLAF-seq and whole-genome shotgun strategy to fine-map the semi-dwarf gene ari-e in barley. BMC Genomics. 2016 11 11; 17(1):911. PMID: 27835941.
    Citations: 5     Fields:    Translation:Animals
  23. Gras S, Van Rhijn I, Shahine A, Cheng TY, Bhati M, Tan LL, Halim H, Tuttle KD, Gapin L, Le Nours J, Moody DB, Rossjohn J. T cell receptor recognition of CD1b presenting a mycobacterial glycolipid. Nat Commun. 2016 10 27; 7:13257. PMID: 27807341.
    Citations: 9     Fields:    Translation:HumansCells
  24. Huang S, Moody DB. Donor-unrestricted T cells in the human CD1 system. Immunogenetics. 2016 08; 68(8):577-96. PMID: 27502318.
    Citations: 6     Fields:    Translation:HumansCells
  25. Buter J, Heijnen D, Wan IC, Bickelhaupt FM, Young DC, Otten E, Moody DB, Minnaard AJ. Stereoselective Synthesis of 1-Tuberculosinyl Adenosine; a Virulence Factor of Mycobacterium tuberculosis. J Org Chem. 2016 08 05; 81(15):6686-96. PMID: 27398789.
    Citations: 1     Fields:    Translation:Cells
  26. Lahiri N, Shah RR, Layre E, Young D, Ford C, Murray MB, Fortune SM, Moody DB. Rifampin Resistance Mutations Are Associated with Broad Chemical Remodeling of Mycobacterium tuberculosis. J Biol Chem. 2016 Jul 01; 291(27):14248-56. PMID: 27226566.
    Citations: 6     Fields:    Translation:Cells
  27. Hayashi JM, Luo CY, Mayfield JA, Hsu T, Fukuda T, Walfield AL, Giffen SR, Leszyk JD, Baer CE, Bennion OT, Madduri A, Shaffer SA, Aldridge BB, Sassetti CM, Sandler SJ, Kinoshita T, Moody DB, Morita YS. Spatially distinct and metabolically active membrane domain in mycobacteria. Proc Natl Acad Sci U S A. 2016 May 10; 113(19):5400-5. PMID: 27114527.
    Citations: 6     Fields:    Translation:Cells
  28. Godfrey DI, Uldrich AP, McCluskey J, Rossjohn J, Moody DB. Corrigendum: The burgeoning family of unconventional T cells. Nat Immunol. 2016 Apr; 17(4):469. PMID: 27002846.
    Citations: 1     Fields:    
  29. Larrouy-Maumus G, Marino LB, Madduri AV, Ragan TJ, Hunt DM, Bassano L, Gutierrez MG, Moody DB, Pavan FR, de Carvalho LP. Cell-Envelope Remodeling as a Determinant of Phenotypic Antibacterial Tolerance in Mycobacterium tuberculosis. ACS Infect Dis. 2016 May 13; 2(5):352-360. PMID: 27231718.
    Citations: 1     Fields:    
  30. Seeliger J, Moody DB. Monstrous Mycobacterial Lipids. Cell Chem Biol. 2016 Feb 18; 23(2):207-209. PMID: 26971870.
    Citations: 1     Fields:    Translation:Cells
  31. Jarrett R, Salio M, Lloyd-Lavery A, Subramaniam S, Bourgeois E, Archer C, Cheung KL, Hardman C, Chandler D, Salimi M, Gutowska-Owsiak D, de la Serna JB, Fallon PG, Jolin H, Mckenzie A, Dziembowski A, Podobas EI, Bal W, Johnson D, Moody DB, Cerundolo V, Ogg G. Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase. Sci Transl Med. 2016 Feb 10; 8(325):325ra18. PMID: 26865566.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  32. Godfrey DI, Uldrich AP, McCluskey J, Rossjohn J, Moody DB. Corrigendum: The burgeoning family of unconventional T cells. Nat Immunol. 2016 Feb; 17(2):214. PMID: 26784266.
    Citations:    Fields:    
  33. Roy S, Ly D, Castro CD, Li NS, Hawk AJ, Altman JD, Meredith SC, Piccirilli JA, Moody DB, Adams EJ. Molecular Analysis of Lipid-Reactive Vd1 ?d T Cells Identified by CD1c Tetramers. J Immunol. 2016 Feb 15; 196(4):1933-42. PMID: 26755823.
    Citations: 9     Fields:    Translation:HumansCells
  34. Martinot AJ, Farrow M, Bai L, Layre E, Cheng TY, Tsai JH, Iqbal J, Annand JW, Sullivan ZA, Hussain MM, Sacchettini J, Moody DB, Seeliger JC, Rubin EJ. Mycobacterial Metabolic Syndrome: LprG and Rv1410 Regulate Triacylglyceride Levels, Growth Rate and Virulence in Mycobacterium tuberculosis. PLoS Pathog. 2016 Jan; 12(1):e1005351. PMID: 26751071.
    Citations: 10     Fields:    Translation:AnimalsCells
  35. Van Rhijn I, van Berlo T, Hilmenyuk T, Cheng TY, Wolf BJ, Tatituri RV, Uldrich AP, Napolitani G, Cerundolo V, Altman JD, Willemsen P, Huang S, Rossjohn J, Besra GS, Brenner MB, Godfrey DI, Moody DB. Human autoreactive T cells recognize CD1b and phospholipids. Proc Natl Acad Sci U S A. 2016 Jan 12; 113(2):380-5. PMID: 26621732.
    Citations:    
  36. Subramaniam S, Aslam A, Misbah SA, Salio M, Cerundolo V, Moody DB, Ogg G. Elevated and cross-responsive CD1a-reactive T cells in bee and wasp venom allergic individuals. Eur J Immunol. 2016 Jan; 46(1):242-52. PMID: 26518614.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  37. Godfrey DI, Uldrich AP, McCluskey J, Rossjohn J, Moody DB. The burgeoning family of unconventional T cells. Nat Immunol. 2015 Nov; 16(11):1114-23. PMID: 26482978.
    Citations: 98     Fields:    Translation:HumansAnimalsCells
  38. Seshadri C, Lin L, Scriba TJ, Peterson G, Freidrich D, Frahm N, DeRosa SC, Moody DB, Prandi J, Gilleron M, Mahomed H, Jiang W, Finak G, Hanekom WA, Gottardo R, McElrath MJ, Hawn TR. T Cell Responses against Mycobacterial Lipids and Proteins Are Poorly Correlated in South African Adolescents. J Immunol. 2015 Nov 15; 195(10):4595-603. PMID: 26466957.
    Citations: 5     Fields:    Translation:HumansCells
  39. Van Rhijn I, Godfrey DI, Rossjohn J, Moody DB. Lipid and small-molecule display by CD1 and MR1. Nat Rev Immunol. 2015 Oct; 15(10):643-54. PMID: 26388332.
    Citations: 40     Fields:    Translation:HumansCells
  40. Kasprowicz VO, Cheng TY, Ndung'u T, Sunpath H, Moody DB, Kasmar AG. HIV Disrupts Human T Cells That Target Mycobacterial Glycolipids. J Infect Dis. 2016 Feb 15; 213(4):628-33. PMID: 26374910.
    Citations: 2     Fields:    Translation:HumansCells
  41. Van Rhijn I, Moody DB. Donor Unrestricted T Cells: A Shared Human T Cell Response. J Immunol. 2015 Sep 01; 195(5):1927-32. PMID: 26297792.
    Citations: 10     Fields:    Translation:HumansCells
  42. Pan SJ, Tapley A, Adamson J, Little T, Urbanowski M, Cohen K, Pym A, Almeida D, Dorasamy A, Layre E, Young DC, Singh R, Patel VB, Wallengren K, Ndung'u T, Wilson D, Moody DB, Bishai W. Biomarkers for Tuberculosis Based on Secreted, Species-Specific, Bacterial Small Molecules. J Infect Dis. 2015 Dec 01; 212(11):1827-34. PMID: 26014799.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  43. Young DC, Layre E, Pan SJ, Tapley A, Adamson J, Seshadri C, Wu Z, Buter J, Minnaard AJ, Coscolla M, Gagneux S, Copin R, Ernst JD, Bishai WR, Snider BB, Moody DB. In vivo biosynthesis of terpene nucleosides provides unique chemical markers of Mycobacterium tuberculosis infection. Chem Biol. 2015 Apr 23; 22(4):516-526. PMID: 25910243.
    Citations: 4     Fields:    Translation:AnimalsCells
  44. Madigan CA, Martinot AJ, Wei JR, Madduri A, Cheng TY, Young DC, Layre E, Murry JP, Rubin EJ, Moody DB. Lipidomic analysis links mycobactin synthase K to iron uptake and virulence in M. tuberculosis. PLoS Pathog. 2015 Mar; 11(3):e1004792. PMID: 25815898.
    Citations: 10     Fields:    Translation:AnimalsCells
  45. Guerin L, Wu V, Houser B, Tilburgs T, de Jong A, Moody DB, Strominger JL. CD1 Antigen Presentation and Autoreactivity in the Pregnant Human Uterus. Am J Reprod Immunol. 2015 Aug; 74(2):126-35. PMID: 25739697.
    Citations: 1     Fields:    Translation:HumansCells
  46. Van Rhijn I, Moody DB. CD1 and mycobacterial lipids activate human T cells. Immunol Rev. 2015 Mar; 264(1):138-53. PMID: 25703557.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  47. Birkinshaw RW, Pellicci DG, Cheng TY, Keller AN, Sandoval-Romero M, Gras S, de Jong A, Uldrich AP, Moody DB, Godfrey DI, Rossjohn J. aß T cell antigen receptor recognition of CD1a presenting self lipid ligands. Nat Immunol. 2015 Mar; 16(3):258-66. PMID: 25642819.
    Citations: 35     Fields:    Translation:HumansCells
  48. Bourgeois EA, Subramaniam S, Cheng TY, De Jong A, Layre E, Ly D, Salimi M, Legaspi A, Modlin RL, Salio M, Cerundolo V, Moody DB, Ogg G. Bee venom processes human skin lipids for presentation by CD1a. J Exp Med. 2015 Feb 09; 212(2):149-63. PMID: 25584012.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  49. van Schaik B, Klarenbeek P, Doorenspleet M, van Kampen A, Moody DB, de Vries N, Van Rhijn I. Discovery of invariant T cells by next-generation sequencing of the human TCR a-chain repertoire. J Immunol. 2014 Nov 15; 193(10):5338-44. PMID: 25339678.
    Citations: 9     Fields:    Translation:HumansCells
  50. Roy S, Ly D, Li NS, Altman JD, Piccirilli JA, Moody DB, Adams EJ. Molecular basis of mycobacterial lipid antigen presentation by CD1c and its recognition by aß T cells. Proc Natl Acad Sci U S A. 2014 Oct 28; 111(43):E4648-57. PMID: 25298532.
    Citations: 18     Fields:    Translation:HumansCells
  51. Layre E, de Jong A, Moody DB. Human T cells use CD1 and MR1 to recognize lipids and small molecules. Curr Opin Chem Biol. 2014 Dec; 23:31-8. PMID: 25271021.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  52. Ly D, Moody DB. The CD1 size problem: lipid antigens, ligands, and scaffolds. Cell Mol Life Sci. 2014 Aug; 71(16):3069-79. PMID: 24658584.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  53. Kawasaki N, Rillahan CD, Cheng TY, Van Rhijn I, Macauley MS, Moody DB, Paulson JC. Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation. J Immunol. 2014 Aug 15; 193(4):1560-6. PMID: 25000981.
    Citations: 11     Fields:    Translation:HumansCells
  54. Van Rhijn I, Gherardin NA, Kasmar A, de Jager W, Pellicci DG, Kostenko L, Tan LL, Bhati M, Gras S, Godfrey DI, Rossjohn J, Moody DB. TCR bias and affinity define two compartments of the CD1b-glycolipid-specific T Cell repertoire. J Immunol. 2014 May 01; 192(9):4054-60. PMID: 24683194.
    Citations: 23     Fields:    Translation:HumansCells
  55. Layre E, Lee HJ, Young DC, Martinot AJ, Buter J, Minnaard AJ, Annand JW, Fortune SM, Snider BB, Matsunaga I, Rubin EJ, Alber T, Moody DB. Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c. Proc Natl Acad Sci U S A. 2014 Feb 25; 111(8):2978-83. PMID: 24516143.
    Citations: 16     Fields:    Translation:Cells
  56. Jones CM, Wells RM, Madduri AV, Renfrow MB, Ratledge C, Moody DB, Niederweis M. Self-poisoning of Mycobacterium tuberculosis by interrupting siderophore recycling. Proc Natl Acad Sci U S A. 2014 Feb 04; 111(5):1945-50. PMID: 24497493.
    Citations: 24     Fields:    Translation:Cells
  57. de Jong A, Cheng TY, Huang S, Gras S, Birkinshaw RW, Kasmar AG, Van Rhijn I, Peña-Cruz V, Ruan DT, Altman JD, Rossjohn J, Moody DB. CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens. Nat Immunol. 2014 Feb; 15(2):177-85. PMID: 24362891.
    Citations: 52     Fields:    Translation:HumansCells
  58. Kasmar AG, Van Rhijn I, Magalhaes KG, Young DC, Cheng TY, Turner MT, Schiefner A, Kalathur RC, Wilson IA, Bhati M, Gras S, Birkinshaw RW, Tan LL, Rossjohn J, Shires J, Jakobsen S, Altman JD, Moody DB. Cutting Edge: CD1a tetramers and dextramers identify human lipopeptide-specific T cells ex vivo. J Immunol. 2013 Nov 01; 191(9):4499-503. PMID: 24089190.
    Citations: 25     Fields:    Translation:HumansCells
  59. Seshadri C, Shenoy M, Wells RD, Hensley-McBain T, Andersen-Nissen E, McElrath MJ, Cheng TY, Moody DB, Hawn TR. Human CD1a deficiency is common and genetically regulated. J Immunol. 2013 Aug 15; 191(4):1586-93. PMID: 23858036.
    Citations: 15     Fields:    Translation:HumansCells
  60. Galagan JE, Minch K, Peterson M, Lyubetskaya A, Azizi E, Sweet L, Gomes A, Rustad T, Dolganov G, Glotova I, Abeel T, Mahwinney C, Kennedy AD, Allard R, Brabant W, Krueger A, Jaini S, Honda B, Yu WH, Hickey MJ, Zucker J, Garay C, Weiner B, Sisk P, Stolte C, Winkler JK, Van de Peer Y, Iazzetti P, Camacho D, Dreyfuss J, Liu Y, Dorhoi A, Mollenkopf HJ, Drogaris P, Lamontagne J, Zhou Y, Piquenot J, Park ST, Raman S, Kaufmann SH, Mohney RP, Chelsky D, Moody DB, Sherman DR, Schoolnik GK. The Mycobacterium tuberculosis regulatory network and hypoxia. Nature. 2013 Jul 11; 499(7457):178-83. PMID: 23823726.
    Citations: 119     Fields:    Translation:Cells
  61. Van Rhijn I, Kasmar A, de Jong A, Gras S, Bhati M, Doorenspleet ME, de Vries N, Godfrey DI, Altman JD, de Jager W, Rossjohn J, Moody DB. A conserved human T cell population targets mycobacterial antigens presented by CD1b. Nat Immunol. 2013 Jul; 14(7):706-13. PMID: 23727893.
    Citations: 67     Fields:    Translation:HumansCells
  62. Ly D, Kasmar AG, Cheng TY, de Jong A, Huang S, Roy S, Bhatt A, van Summeren RP, Altman JD, Jacobs WR, Adams EJ, Minnaard AJ, Porcelli SA, Moody DB. CD1c tetramers detect ex vivo T cell responses to processed phosphomycoketide antigens. J Exp Med. 2013 Apr 08; 210(4):729-41. PMID: 23530121.
    Citations: 36     Fields:    Translation:HumansCells
  63. Van Rhijn I, Ly D, Moody DB. CD1a, CD1b, and CD1c in immunity against mycobacteria. Adv Exp Med Biol. 2013; 783:181-97. PMID: 23468110.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  64. Seshadri C, Turner MT, Lewinsohn DM, Moody DB, Van Rhijn I. Lipoproteins are major targets of the polyclonal human T cell response to Mycobacterium tuberculosis. J Immunol. 2013 Jan 01; 190(1):278-84. PMID: 23197260.
    Citations: 9     Fields:    Translation:HumansCells
  65. Nguyen TK, Koets AP, Vordermeier M, Jervis PJ, Cox LR, Graham SP, Santema WJ, Moody DB, van Calenbergh S, Zajonc DM, Besra GS, Van Rhijn I. The bovine CD1D gene has an unusual gene structure and is expressed but cannot present a-galactosylceramide with a C26 fatty acid. Int Immunol. 2013 Feb; 25(2):91-8. PMID: 22968995.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  66. Layre E, Moody DB. Lipidomic profiling of model organisms and the world's major pathogens. Biochimie. 2013 Jan; 95(1):109-15. PMID: 22971440.
    Citations: 9     Fields:    Translation:HumansCells
  67. Zeissig S, Murata K, Sweet L, Publicover J, Hu Z, Kaser A, Bosse E, Iqbal J, Hussain MM, Balschun K, Röcken C, Arlt A, Günther R, Hampe J, Schreiber S, Baron JL, Moody DB, Liang TJ, Blumberg RS. Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity. Nat Med. 2012 Jul; 18(7):1060-8. PMID: 22706385.
    Citations: 92     Fields:    Translation:HumansAnimalsCells
  68. Hong S, Cheng TY, Layre E, Sweet L, Young DC, Posey JE, Butler WR, Moody DB. Ultralong C100 mycolic acids support the assignment of Segniliparus as a new bacterial genus. PLoS One. 2012; 7(6):e39017. PMID: 22720018.
    Citations: 2     Fields:    Translation:Cells
  69. León L, Tatituri RV, Grenha R, Sun Y, Barral DC, Minnaard AJ, Bhowruth V, Veerapen N, Besra GS, Kasmar A, Peng W, Moody DB, Grabowski GA, Brenner MB. Saposins utilize two strategies for lipid transfer and CD1 antigen presentation. Proc Natl Acad Sci U S A. 2012 Mar 20; 109(12):4357-64. PMID: 22331868.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  70. Madigan CA, Cheng TY, Layre E, Young DC, McConnell MJ, Debono CA, Murry JP, Wei JR, Barry CE, Rodriguez GM, Matsunaga I, Rubin EJ, Moody DB. Lipidomic discovery of deoxysiderophores reveals a revised mycobactin biosynthesis pathway in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2012 Jan 24; 109(4):1257-62. PMID: 22232695.
    Citations: 23     Fields:    Translation:Cells
  71. Layre E, Sweet L, Hong S, Madigan CA, Desjardins D, Young DC, Cheng TY, Annand JW, Kim K, Shamputa IC, McConnell MJ, Debono CA, Behar SM, Minnaard AJ, Murray M, Barry CE, Matsunaga I, Moody DB. A comparative lipidomics platform for chemotaxonomic analysis of Mycobacterium tuberculosis. Chem Biol. 2011 Dec 23; 18(12):1537-49. PMID: 22195556.
    Citations: 43     Fields:    Translation:AnimalsCells
  72. Pang JM, Layre E, Sweet L, Sherrid A, Moody DB, Ojha A, Sherman DR. The polyketide Pks1 contributes to biofilm formation in Mycobacterium tuberculosis. J Bacteriol. 2012 Feb; 194(3):715-21. PMID: 22123254.
    Citations: 26     Fields:    Translation:HumansCells
  73. Huang S, Cheng TY, Young DC, Layre E, Madigan CA, Shires J, Cerundolo V, Altman JD, Moody DB. Discovery of deoxyceramides and diacylglycerols as CD1b scaffold lipids among diverse groove-blocking lipids of the human CD1 system. Proc Natl Acad Sci U S A. 2011 Nov 29; 108(48):19335-40. PMID: 22087000.
    Citations: 23     Fields:    Translation:HumansCells
  74. Kasmar AG, van Rhijn I, Cheng TY, Turner M, Seshadri C, Schiefner A, Kalathur RC, Annand JW, de Jong A, Shires J, Leon L, Brenner M, Wilson IA, Altman JD, Moody DB. CD1b tetramers bind aß T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans. J Exp Med. 2011 Aug 29; 208(9):1741-7. PMID: 21807869.
    Citations: 52     Fields:    Translation:HumansCells
  75. Yang JS, Valente C, Polishchuk RS, Turacchio G, Layre E, Moody DB, Leslie CC, Gelb MH, Brown WJ, Corda D, Luini A, Hsu VW. COPI acts in both vesicular and tubular transport. Nat Cell Biol. 2011 Jul 03; 13(8):996-1003. PMID: 21725317.
    Citations: 44     Fields:    Translation:HumansCells
  76. Lockridge JL, Chen X, Zhou Y, Rajesh D, Roenneburg DA, Hegde S, Gerdts S, Cheng TY, Anderson RJ, Painter GF, Moody DB, Burlingham WJ, Gumperz JE. Analysis of the CD1 antigen presenting system in humanized SCID mice. PLoS One. 2011; 6(6):e21701. PMID: 21738769.
    Citations: 18     Fields:    Translation:HumansAnimals
  77. Yakimchuk K, Roura-Mir C, Magalhaes KG, de Jong A, Kasmar AG, Granter SR, Budd R, Steere A, Pena-Cruz V, Kirschning C, Cheng TY, Moody DB. Borrelia burgdorferi infection regulates CD1 expression in human cells and tissues via IL1-ß. Eur J Immunol. 2011 Mar; 41(3):694-705. PMID: 21246541.
    Citations: 20     Fields:    Translation:HumansCells
  78. Mureithi MW, Cohen K, Moodley R, Poole D, Mncube Z, Kasmar A, Moody DB, Goulder PJ, Walker BD, Altfeld M, Ndung'u T. Impairment of CD1d-restricted natural killer T cells in chronic HIV type 1 clade C infection. AIDS Res Hum Retroviruses. 2011 May; 27(5):501-9. PMID: 20942750.
    Citations: 5     Fields:    Translation:HumansCells
  79. de Jong A, Peña-Cruz V, Cheng TY, Clark RA, Van Rhijn I, Moody DB. CD1a-autoreactive T cells are a normal component of the human aß T cell repertoire. Nat Immunol. 2010 Dec; 11(12):1102-9. PMID: 21037579.
    Citations: 96     Fields:    Translation:HumansCells
  80. Drage MG, Tsai HC, Pecora ND, Cheng TY, Arida AR, Shukla S, Rojas RE, Seshadri C, Moody DB, Boom WH, Sacchettini JC, Harding CV. Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2. Nat Struct Mol Biol. 2010 Sep; 17(9):1088-95. PMID: 20694006.
    Citations: 38     Fields:    Translation:HumansCells
  81. Matsunaga I, Moody DB. Mincle is a long sought receptor for mycobacterial cord factor. J Exp Med. 2009 Dec 21; 206(13):2865-8. PMID: 20008525.
    Citations: 27     Fields:    Translation:Animals
  82. Ter Horst B, Seshadri C, Sweet L, Young DC, Feringa BL, Moody DB, Minnaard AJ. Asymmetric synthesis and structure elucidation of a glycerophospholipid from Mycobacterium tuberculosis. J Lipid Res. 2010 May; 51(5):1017-22. PMID: 19965610.
    Citations: 2     Fields:    Translation:Cells
  83. Van Rhijn I, Nguyen TK, Michel A, Cooper D, Govaerts M, Cheng TY, van Eden W, Moody DB, Coetzer JA, Rutten V, Koets AP. Low cross-reactivity of T-cell responses against lipids from Mycobacterium bovis and M. avium paratuberculosis during natural infection. Eur J Immunol. 2009 Nov; 39(11):3031-41. PMID: 19688747.
    Citations: 8     Fields:    Translation:AnimalsCells
  84. Siegrist MS, Unnikrishnan M, McConnell MJ, Borowsky M, Cheng TY, Siddiqi N, Fortune SM, Moody DB, Rubin EJ. Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition. Proc Natl Acad Sci U S A. 2009 Nov 03; 106(44):18792-7. PMID: 19846780.
    Citations: 92     Fields:    Translation:AnimalsCells
  85. Felio K, Nguyen H, Dascher CC, Choi HJ, Li S, Zimmer MI, Colmone A, Moody DB, Brenner MB, Wang CR. CD1-restricted adaptive immune responses to Mycobacteria in human group 1 CD1 transgenic mice. J Exp Med. 2009 Oct 26; 206(11):2497-509. PMID: 19808251.
    Citations: 48     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  86. Colijn C, Brandes A, Zucker J, Lun DS, Weiner B, Farhat MR, Cheng TY, Moody DB, Murray M, Galagan JE. Interpreting expression data with metabolic flux models: predicting Mycobacterium tuberculosis mycolic acid production. PLoS Comput Biol. 2009 Aug; 5(8):e1000489. PMID: 19714220.
    Citations: 115     Fields:    Translation:Cells
  87. Young DC, Kasmar A, Moraski G, Cheng TY, Walz AJ, Hu J, Xu Y, Endres GW, Uzieblo A, Zajonc D, Costello CE, Miller MJ, Moody DB. Synthesis of dideoxymycobactin antigens presented by CD1a reveals T cell fine specificity for natural lipopeptide structures. J Biol Chem. 2009 Sep 11; 284(37):25087-96. PMID: 19605355.
    Citations: 10     Fields:    Translation:HumansCells
  88. Kasmar A, Van Rhijn I, Moody DB. The evolved functions of CD1 during infection. Curr Opin Immunol. 2009 Aug; 21(4):397-403. PMID: 19541469.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  89. Van Rhijn I, Young DC, De Jong A, Vazquez J, Cheng TY, Talekar R, Barral DC, Barral D, León L, Brenner MB, Katz JT, Riese R, Ruprecht RM, O'Connor PB, Costello CE, Porcelli SA, Briken V, Moody DB. CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids. J Exp Med. 2009 Jun 08; 206(6):1409-22. PMID: 19468063.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  90. Matsunaga I, Naka T, Talekar RS, McConnell MJ, Katoh K, Nakao H, Otsuka A, Behar SM, Yano I, Moody DB, Sugita M. Mycolyltransferase-mediated glycolipid exchange in Mycobacteria. J Biol Chem. 2008 Oct 24; 283(43):28835-41. PMID: 18703502.
    Citations: 15     Fields:    Translation:AnimalsCells
  91. Relloso M, Cheng TY, Im JS, Parisini E, Roura-Mir C, DeBono C, Zajonc DM, Murga LF, Ondrechen MJ, Wilson IA, Porcelli SA, Moody DB. pH-dependent interdomain tethers of CD1b regulate its antigen capture. Immunity. 2008 Jun; 28(6):774-86. PMID: 18538591.
    Citations: 20     Fields:    Translation:HumansCells
  92. Leslie DS, Dascher CC, Cembrola K, Townes MA, Hava DL, Hugendubler LC, Mueller E, Fox L, Roura-Mir C, Moody DB, Vincent MS, Gumperz JE, Illarionov PA, Besra GS, Reynolds CG, Brenner MB. Serum lipids regulate dendritic cell CD1 expression and function. Immunology. 2008 Nov; 125(3):289-301. PMID: 18445008.
    Citations: 20     Fields:    Translation:HumansCells
  93. Smed-Sörensen A, Moll M, Cheng TY, Loré K, Norlin AC, Perbeck L, Moody DB, Spetz AL, Sandberg JK. IgG regulates the CD1 expression profile and lipid antigen-presenting function in human dendritic cells via FcgammaRIIa. Blood. 2008 May 15; 111(10):5037-46. PMID: 18337560.
    Citations: 18     Fields:    Translation:HumansCells
  94. de Jong A, Arce EC, Cheng TY, van Summeren RP, Feringa BL, Dudkin V, Crich D, Matsunaga I, Minnaard AJ, Moody DB. CD1c presentation of synthetic glycolipid antigens with foreign alkyl branching motifs. Chem Biol. 2007 Nov; 14(11):1232-42. PMID: 18022562.
    Citations: 17     Fields:    Translation:HumansCells
  95. Moody DB. Immunology: how a T cell sees sugar. Nature. 2007 Jul 05; 448(7149):36-7. PMID: 17581593.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  96. CD1 Antigen Presentation to T cells (DB Moody). 2006; in press.
  97. Raman S, Puyang X, Cheng TY, Young DC, Moody DB, Husson RN. Mycobacterium tuberculosis SigM positively regulates Esx secreted protein and nonribosomal peptide synthetase genes and down regulates virulence-associated surface lipid synthesis. J Bacteriol. 2006 Dec; 188(24):8460-8. PMID: 17028284.
    Citations: 21     Fields:    Translation:HumansCells
  98. Lee L, DeBono CA, Campagna DR, Young DC, Moody DB, Fleming MD. Loss of the acyl-CoA binding protein (Acbp) results in fatty acid metabolism abnormalities in mouse hair and skin. J Invest Dermatol. 2007 Jan; 127(1):16-23. PMID: 16902415.
    Citations: 16     Fields:    Translation:Animals
  99. Moody DB. TLR gateways to CD1 function. Nat Immunol. 2006 Aug; 7(8):811-7. PMID: 16855607.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  100. Cheng T, Relloso M, Van Rhijn I, Young DC, Besra G, Briken V, Zajonc D, Wilson IA, Porcelli S and DB Moody . Role of lipid trimming and CD1 groove size in cellular antigen presentation. EMBO Journal. 2006; in press.
  101. Lance Lee, C. Anthony Debono, Dean R. Campagna, David C. Young, D. Branch Moody, Mark D. Fleming. Loss of the acyl-CoA binding protein results in fatty acid metabolism abnormalities in mouse hair and skin. Journal of Investigative Dermatology. 2006; in press.
  102. Cheng TY, Relloso M, Van Rhijn I, Young DC, Besra GS, Briken V, Zajonc DM, Wilson IA, Porcelli S, Moody DB. Role of lipid trimming and CD1 groove size in cellular antigen presentation. EMBO J. 2006 Jul 12; 25(13):2989-99. PMID: 16794581.
    Citations: 23     Fields:    Translation:HumansCells
  103. van Summeren RP, Moody DB, Feringa BL, Minnaard AJ. Total synthesis of enantiopure beta-D-mannosyl phosphomycoketides from Mycobacterium tuberculosis. J Am Chem Soc. 2006 Apr 12; 128(14):4546-7. PMID: 16594671.
    Citations: 11     Fields:    Translation:Cells
  104. Young DC, Moody DB. T-cell recognition of glycolipids presented by CD1 proteins. Glycobiology. 2006 Jul; 16(7):103R-112R. PMID: 16597658.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  105. Cheng, T. Y., de Jong, A., van Summeren, R., Minnaard, A. J., Crick, D. C., Porcelli, S. A., and Moody, D. B. . T cell receptor fine specificity for recognition of polyketide antigens presented by CD1c. Journal of Immunology. 2006; 106:S51.
  106. Moody DB. The surprising diversity of lipid antigens for CD1-restricted T cells. Adv Immunol. 2006; 89:87-139. PMID: 16682273.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  107. van den Elzen P, Garg S, León L, Brigl M, Leadbetter EA, Gumperz JE, Dascher CC, Cheng TY, Sacks FM, Illarionov PA, Besra GS, Kent SC, Moody DB, Brenner MB. Apolipoprotein-mediated pathways of lipid antigen presentation. Nature. 2005 Oct 06; 437(7060):906-10. PMID: 16208376.
    Citations: 121     Fields:    Translation:HumansAnimalsCells
  108. D. Branch Moody Steven A. Porcelli. Antigen Presenting Cells (Kropshofer and Vogt). 2005; 129-150.
  109. Roura-Mir C, Wang L, Cheng TY, Matsunaga I, Dascher CC, Peng SL, Fenton MJ, Kirschning C, Moody DB. Mycobacterium tuberculosis regulates CD1 antigen presentation pathways through TLR-2. J Immunol. 2005 Aug 01; 175(3):1758-66. PMID: 16034117.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  110. Van Rhijn I, Zajonc DM, Wilson IA, Moody DB. T-cell activation by lipopeptide antigens. Curr Opin Immunol. 2005 Jun; 17(3):222-9. PMID: 15886110.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  111. Moody DB, Zajonc DM, Wilson IA. Anatomy of CD1-lipid antigen complexes. Nat Rev Immunol. 2005 May; 5(5):387-99. PMID: 15864273.
    Citations: 59     Fields:    Translation:HumansCells
  112. Roura-Mir C, Catálfamo M, Cheng TY, Marqusee E, Besra GS, Jaraquemada D, Moody DB. CD1a and CD1c activate intrathyroidal T cells during Graves' disease and Hashimoto's thyroiditis. J Immunol. 2005 Mar 15; 174(6):3773-80. PMID: 15749918.
    Citations: 19     Fields:    Translation:HumansCells
  113. Zajonc DM, Crispin MD, Bowden TA, Young DC, Cheng TY, Hu J, Costello CE, Rudd PM, Dwek RA, Miller MJ, Brenner MB, Moody DB, Wilson IA. Molecular mechanism of lipopeptide presentation by CD1a. Immunity. 2005 Feb; 22(2):209-19. PMID: 15723809.
    Citations: 46     Fields:    Translation:HumansCells
  114. Matsunaga I, Bhatt A, Young DC, Cheng TY, Eyles SJ, Besra GS, Briken V, Porcelli SA, Costello CE, Jacobs WR, Moody DB. Mycobacterium tuberculosis pks12 produces a novel polyketide presented by CD1c to T cells. J Exp Med. 2004 Dec 20; 200(12):1559-69. PMID: 15611286.
    Citations: 54     Fields:    Translation:HumansCells
  115. D. Branch Moody, David C. Young and Ildiko Van Rhijn. Methods and Compositions for Immunomodulation. (phenylpenatmethyldihydrobenzofuran sulfonates and nonlipidic antigens). 2004.
  116. Van Rhijn I, Young DC, Im JS, Levery SB, Illarionov PA, Besra GS, Porcelli SA, Gumperz J, Cheng TY, Moody DB. CD1d-restricted T cell activation by nonlipidic small molecules. Proc Natl Acad Sci U S A. 2004 Sep 14; 101(37):13578-83. PMID: 15342907.
    Citations: 38     Fields:    Translation:HumansCells
  117. D. Branch Moody, David C. Young and Catherine E. Costello. Methods and Compositions for Immunomodulation using CD1 antigens. (Lipopeptide antigens). 2004.
  118. Moody DB, Young DC, Cheng TY, Rosat JP, Roura-Mir C, O'Connor PB, Zajonc DM, Walz A, Miller MJ, Levery SB, Wilson IA, Costello CE, Brenner MB. T cell activation by lipopeptide antigens. Science. 2004 Jan 23; 303(5657):527-31. PMID: 14739458.
    Citations: 87     Fields:    Translation:HumansCells
  119. Roura-Mir C, Moody DB. Sorting out self and microbial lipid antigens for CD1. Microbes Infect. 2003 Oct; 5(12):1137-48. PMID: 14554256.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  120. Rauch J, Gumperz J, Robinson C, Sköld M, Roy C, Young DC, Lafleur M, Moody DB, Brenner MB, Costello CE, Behar SM. Structural features of the acyl chain determine self-phospholipid antigen recognition by a CD1d-restricted invariant NKT (iNKT) cell. J Biol Chem. 2003 Nov 28; 278(48):47508-15. PMID: 12963715.
    Citations: 40     Fields:    Translation:HumansAnimalsCells
  121. Ulrichs T, Moody DB, Grant E, Kaufmann SH, Porcelli SA. T-cell responses to CD1-presented lipid antigens in humans with Mycobacterium tuberculosis infection. Infect Immun. 2003 Jun; 71(6):3076-87. PMID: 12761085.
    Citations: 43     Fields:    Translation:HumansCells
  122. Steven A. Porcelli and D. Branch Moody. Synthetic Antigens for CD1-restricted Immune Responses. 2003.
  123. Reilly CA, Ehlhardt WJ, Jackson DA, Kulanthaivel P, Mutlib AE, Espina RJ, Moody DE, Crouch DJ, Yost GS. Metabolism of capsaicin by cytochrome P450 produces novel dehydrogenated metabolites and decreases cytotoxicity to lung and liver cells. Chem Res Toxicol. 2003 Mar; 16(3):336-49. PMID: 12641434.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  124. Moody DB, Porcelli SA. Intracellular pathways of CD1 antigen presentation. Nat Rev Immunol. 2003 Jan; 3(1):11-22. PMID: 12511872.
    Citations: 53     Fields:    Translation:HumansAnimalsCells
  125. Gurcha SS, Baulard AR, Kremer L, Locht C, Moody DB, Muhlecker W, Costello CE, Crick DC, Brennan PJ, Besra GS. Ppm1, a novel polyprenol monophosphomannose synthase from Mycobacterium tuberculosis. Biochem J. 2002 Jul 15; 365(Pt 2):441-50. PMID: 11931640.
    Citations: 37     Fields:    Translation:Cells
  126. Moody DB, Briken V, Cheng TY, Roura-Mir C, Guy MR, Geho DH, Tykocinski ML, Besra GS, Porcelli SA. Lipid length controls antigen entry into endosomal and nonendosomal pathways for CD1b presentation. Nat Immunol. 2002 May; 3(5):435-42. PMID: 11938350.
    Citations: 52     Fields:    Translation:HumansCells
  127. Colonna DM, Kilgus D, Brown W, Challa V, Stump DA, Moody DM. Acute brain fat embolization occurring after total hip arthroplasty in the absence of a patent foramen ovale. Anesthesiology. 2002 Apr; 96(4):1027-9. PMID: 11964616.
    Citations: 6     Fields:    Translation:Humans
  128. Moody DB, Porcelli SA. CD1 trafficking: invariant chain gives a new twist to the tale. Immunity. 2001 Dec; 15(6):861-5. PMID: 11754808.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  129. Moody DB, Besra GS. Glycolipid targets of CD1-mediated T-cell responses. Immunology. 2001 Nov; 104(3):243-51. PMID: 11722638.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  130. Moody DB. Polyisoprenyl glycolipids as targets of CD1-mediated T cell responses. Cell Mol Life Sci. 2001 Sep; 58(10):1461-74. PMID: 11693527.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  131. Niazi K, Chiu M, Mendoza R, Degano M, Khurana S, Moody D, Melián A, Wilson I, Kronenberg M, Porcelli S, Modlin R. The A' and F' pockets of human CD1b are both required for optimal presentation of lipid antigens to T cells. J Immunol. 2001 Feb 15; 166(4):2562-70. PMID: 11160317.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  132. Niazi K, Chiu M, Mendoza R, Degano M, Khurana S, Moody D, Melian A, Wilson I, Kronenberg M, Porcelli S, Modlin R. The A' and F' pockets of human CD1b are both required for optimal presentation of lipid antigens to T cells. Journal of Immunology. 2001; 166(4):2562-2570.
  133. Briken V, Moody DB, Porcelli SA. Diversification of CD1 proteins: sampling the lipid content of different cellular compartments. Semin Immunol. 2000 Dec; 12(6):517-25. PMID: 11145857.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  134. Moody DB, Guy MR, Grant E, Cheng TY, Brenner MB, Besra GS, Porcelli SA. CD1b-mediated T cell recognition of a glycolipid antigen generated from mycobacterial lipid and host carbohydrate during infection. J Exp Med. 2000 Oct 02; 192(7):965-76. PMID: 11015438.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  135. Geho DH, Fayen JD, Jackman RM, Moody DB, Porcelli SA, Tykocinski ML. Glycosyl-phosphatidylinositol reanchoring unmasks distinct antigen-presenting pathways for CD1b and CD1c. J Immunol. 2000 Aug 01; 165(3):1272-7. PMID: 10903726.
    Citations: 2     Fields:    Translation:HumansCells
  136. Moody DB, Ulrichs T, Mühlecker W, Young DC, Gurcha SS, Grant E, Rosat JP, Brenner MB, Costello CE, Besra GS, Porcelli SA. CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection. Nature. 2000 Apr 20; 404(6780):884-8. PMID: 10786796.
    Citations: 115     Fields:    Translation:HumansCells
  137. Moody DB, Besra GS, Wilson IA, Porcelli SA. The molecular basis of CD1-mediated presentation of lipid antigens. Immunol Rev. 1999 Dec; 172:285-96. PMID: 10631954.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  138. Moody DB, Reinhold BB, Reinhold VN, Besra GS, Porcelli SA. Uptake and processing of glycosylated mycolates for presentation to CD1b-restricted T cells. Immunol Lett. 1999 Jan; 65(1-2):85-91. PMID: 10065632.
    Citations: 8     Fields:    Translation:HumansCells
  139. Jackman RM, Moody DB, Porcelli SA. Mechanisms of lipid antigen presentation by CD1. Crit Rev Immunol. 1999; 19(1):49-63. PMID: 9987600.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  140. Sugita M, Moody DB, Jackman RM, Grant EP, Rosat JP, Behar SM, Peters PJ, Porcelli SA, Brenner MB. CD1--a new paradigm for antigen presentation and T cell activation. Clin Immunol Immunopathol. 1998 Apr; 87(1):8-14. PMID: 9576005.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  141. Jackman RM, Stenger S, Lee A, Moody DB, Rogers RA, Niazi KR, Sugita M, Modlin RL, Peters PJ, Porcelli SA. The tyrosine-containing cytoplasmic tail of CD1b is essential for its efficient presentation of bacterial lipid antigens. Immunity. 1998 Mar; 8(3):341-51. PMID: 9529151.
    Citations: 36     Fields:    Translation:HumansCells
  142. Ernst WA, Maher J, Cho S, Niazi KR, Chatterjee D, Moody DB, Besra GS, Watanabe Y, Jensen PE, Porcelli SA, Kronenberg M, Modlin RL. Molecular interaction of CD1b with lipoglycan antigens. Immunity. 1998 Mar; 8(3):331-40. PMID: 9529150.
    Citations: 44     Fields:    Translation:Cells
  143. Moody DB, Reinhold BB, Guy MR, Beckman EM, Frederique DE, Furlong ST, Ye S, Reinhold VN, Sieling PA, Modlin RL, Besra GS, Porcelli SA. Structural requirements for glycolipid antigen recognition by CD1b-restricted T cells. Science. 1997 Oct 10; 278(5336):283-6. PMID: 9323206.
    Citations: 113     Fields:    Translation:HumansCells
  144. Moody DB, Sugita M, Peters PJ, Brenner MB, Porcelli SA. The CD1-restricted T-cell response to mycobacteria. Res Immunol. 1996 Oct-Dec; 147(8-9):550-9. PMID: 9127887.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  145. Montoya JG, Lowe KE, Clayberger C, Moody D, Do D, Remington JS, Talib S, Subauste CS. Human CD4+ and CD8+ T lymphocytes are both cytotoxic to Toxoplasma gondii-infected cells. Infect Immun. 1996 Jan; 64(1):176-81. PMID: 8557337.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  146. Moody DB, Robinson JC, Ewing CM, Lazenby AJ, Isaacs WB. Interleukin-2 transfected prostate cancer cells generate a local antitumor effect in vivo. Prostate. 1994 May; 24(5):244-51. PMID: 8170837.
    Citations: 3     Fields:    Translation:AnimalsCells
  147. Ho M, Armstrong J, McMahon D, Pazin G, Huang XL, Rinaldo C, Whiteside T, Tripoli C, Levine G, Moody D, et al. A phase 1 study of adoptive transfer of autologous CD8+ T lymphocytes in patients with acquired immunodeficiency syndrome (AIDS)-related complex or AIDS. Blood. 1993 Apr 15; 81(8):2093-101. PMID: 8471768.
    Citations: 9     Fields:    Translation:HumansCellsCTClinical Trials
  148. Moody DB. Healing power in the Marian miracle books of Bavarian healing shrines, 1489-1523 A.D. J Hist Med Allied Sci. 1992 Jan; 47(1):68-90. PMID: 1556445.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.