Harvard Catalyst Profiles

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Michael William Donnino, M.D.

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Overview
Dr. Michael Donnino is an attending physician in the Department of Emergency Medicine and Division of Pulmonary/Critical Care Medicine at Beth Israel Deaconess Medical Center. His clinical practice spans both the intensive care unit as well as the emergency department. Dr. Donnino was the first person in the country to train in a 6-year combined emergency medicine, internal medicine, and critical care program leading to board certification in all three areas. Dr. Donnino is also the Director of the Center for Resuscitation Science and Director of Critical Care in Emergency Medicine. Dr. Donnino’s research interests include clinical trials and clinical investigations in septic shock and cardiac arrest. In the field of cardiac arrest, Dr. Donnino is the lead investigator of a multi-center clinical trial evaluating the use of steroids in post-arrest shock and a multi-center trial evaluating thiamine as a metabolic resuscitator in septic shock. Other notable studies include an investigation in microcirculatory dysfunction post-arrest, an evaluation of the human metabolome in sepsis and post-cardiac arrest, and severity of illness scoring systems in post-cardiac arrest patients. Dr. Donnino is a member of the Advanced Cardiac Life Support (ACLS) Subcommittee at the American Heart Association and co-author of sections of the 2010 ACLS guidelines.

Mentoring
Thiamine Deficiency in Critically Ill Patients with Sepsis
Summer, 06/18/07 - 08/10/07

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. T32HL155020 (DONNINO, MICHAEL WILLIAM ;MITTLEMAN, MURRAY A;PARIKH, SAMIR M) Dec 1, 2020 - Jan 31, 2026
    NIH
    Training Program in Resuscitation Science
    Role: Principal Investigator
  2. R01DK112886 (DONNINO, MICHAEL WILLIAM) Sep 1, 2018 - Jun 30, 2023
    NIH
    Thiamine as Adjunctive Therapy for Diabetic Ketoacidosis
    Role: Principal Investigator
  3. R03AA026093 (DONNINO, MICHAEL WILLIAM) Sep 1, 2018 - Aug 31, 2021
    NIH
    Thiamine in septic shock patients with alcohol abuse
    Role: Principal Investigator
  4. R01HL136705 (DONNINO, MICHAEL WILLIAM) Apr 1, 2017 - Mar 31, 2022
    NIH
    Thiamine As A Metabolic Resuscitator In Cardiac Arrest
    Role: Principal Investigator
  5. K24HL127101 (DONNINO, MICHAEL WILLIAM) Sep 9, 2015 - Aug 31, 2025
    NIH
    Thaimine as an adjunct metabolic resuscitator in cardiac arrest
    Role: Principal Investigator

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.