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Last Name

profileJason Lyell Vassy, M.D.

TitleAssistant Professor of Medicine
InstitutionBrigham and Women's Hospital
AddressBrigham & Woman's Hospital
Division of General Internal Medicine, 9 (152G)
150 S Huntington Ave
Jamaica Plain MA 02130
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IK2CX001262     (VASSY, JASON L)Jan 1, 2016 - Dec 31, 2020
Clinical safety and efficacy of pharmacogenetics in Veteran care
Role: Principal Investigator

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Christensen KD, Vassy JL, Phillips KA, Blout CL, Azzariti DR, Lu CY, Robinson JO, Lee K, Douglas MP, Yeh JM, Machini K, Stout NK, Rehm HL, McGuire AL, Green RC, Dukhovny D. Short-term costs of integrating whole-genome sequencing into primary care and cardiology settings: a pilot randomized trial. Genet Med. 2018 Mar 22. PMID: 29565423.
    View in: PubMed
  2. Vassy JL, Davis JK, Kirby C, Richardson IJ, Green RC, McGuire AL, Ubel PA. How Primary Care Providers Talk to Patients about Genome Sequencing Results: Risk, Rationale, and Recommendation. J Gen Intern Med. 2018 Jan 26. PMID: 29374360.
    View in: PubMed
  3. Vassy JL, He W, Florez JC, Meigs JB, Grant RW. Six-Year Diabetes Incidence After Genetic Risk Testing and Counseling: A Randomized Clinical Trial. Diabetes Care. 2018 Mar; 41(3):e25-e26. PMID: 29305403.
    View in: PubMed
  4. Vassy JL, Ho YL, Honerlaw J, Cho K, Gaziano JM, Wilson PWF, Gagnon DR. Yield and bias in defining a cohort study baseline from electronic health record data. J Biomed Inform. 2018 Feb; 78:54-59. PMID: 29305952.
    View in: PubMed
  5. Vassy JL, Christensen KD, Schonman EF, Blout CL, Robinson JO, Krier JB, Diamond PM, Lebo M, Machini K, Azzariti DR, Dukhovny D, Bates DW, MacRae CA, Murray MF, Rehm HL, McGuire AL, Green RC. The Impact of Whole-Genome Sequencing on the Primary Care and Outcomes of Healthy Adult Patients: A Pilot Randomized Trial. Ann Intern Med. 2017 Jun 27. PMID: 28654958.
    View in: PubMed
  6. Jamal L, Robinson JO, Christensen KD, Blumenthal-Barby J, Slashinski MJ, Perry DL, Vassy JL, Wycliff J, Green RC, McGuire AL. When bins blur: Patient perspectives on categories of results from clinical whole genome sequencing. AJOB Empir Bioeth. 2017 Apr-Jun; 8(2):82-88. PMID: 28949844.
    View in: PubMed
  7. Carere DA, VanderWeele TJ, Vassy JL, van der Wouden CH, Roberts JS, Kraft P, Green RC. Prescription medication changes following direct-to-consumer personal genomic testing: findings from the Impact of Personal Genomics (PGen) Study. Genet Med. 2017 May; 19(5):537-545. PMID: 27657683.
    View in: PubMed
  8. Vassy JL, Bates DW, Murray MF. Appropriateness: A Key to Enabling the Use of Genomics in Clinical Practice? Am J Med. 2016 06; 129(6):551-3. PMID: 26965302.
    View in: PubMed
  9. Bray MS, Loos RJ, McCaffery JM, Ling C, Franks PW, Weinstock GM, Snyder MP, Vassy JL, Agurs-Collins T. NIH working group report-using genomic information to guide weight management: From universal to precision treatment. Obesity (Silver Spring). 2016 Jan; 24(1):14-22. PMID: 26692578; PMCID: PMC4689320.
  10. Lupo PJ, Robinson JO, Diamond PM, Jamal L, Danysh HE, Blumenthal-Barby J, Lehmann LS, Vassy JL, Christensen KD, Green RC, McGuire AL. Patients' perceived utility of whole-genome sequencing for their healthcare: findings from the MedSeq project. Per Med. 2016 Jan 01; 13(1):13-20. PMID: 27019659.
    View in: PubMed
  11. Christensen KD, Vassy JL, Jamal L, Lehmann LS, Slashinski MJ, Perry DL, Robinson JO, Blumenthal-Barby J, Feuerman LZ, Murray MF, Green RC, McGuire AL. Are physicians prepared for whole genome sequencing? a qualitative analysis. Clin Genet. 2016 Feb; 89(2):228-34. PMID: 26080898; PMCID: PMC4683111 [Available on 02/01/17].
  12. Vassy JL, Korf BR, Green RC. How to know when physicians are ready for genomic medicine. Sci Transl Med. 2015 May 13; 7(287):287fs19. PMID: 25971999; PMCID: PMC4519005.
  13. Dauriz M, Porneala BC, Guo X, Bielak LF, Peyser PA, Durant NH, Carnethon MR, Bonadonna RC, Bonora E, Bowden DW, Florez JC, Fornage M, Hivert MF, Jacobs DR, Kabagambe EK, Lewis CE, Murabito JM, Rasmussen-Torvik LJ, Rich SS, Vassy JL, Yao J, Carr JJ, Kardia SL, Siscovick D, O'Donnell CJ, Rotter JI, Dupuis J, Meigs JB. Association of a 62 Variants Type 2 Diabetes Genetic Risk Score With Markers of Subclinical Atherosclerosis: A Transethnic, Multicenter Study. Circ Cardiovasc Genet. 2015 Jun; 8(3):507-15. PMID: 25805414; PMCID: PMC4472563.
  14. Vassy JL, McLaughlin HM, McLaughlin HL, MacRae CA, Seidman CE, Lautenbach D, Krier JB, Lane WJ, Kohane IS, Murray MF, McGuire AL, Rehm HL, Green RC. A one-page summary report of genome sequencing for the healthy adult. Public Health Genomics. 2015; 18(2):123-9. PMID: 25612602; PMCID: PMC4348325.
  15. Vassy JL, Christensen KD, Slashinski MJ, Lautenbach DM, Raghavan S, Robinson JO, Blumenthal-Barby J, Feuerman LZ, Lehmann LS, Murray MF, Green RC, McGuire AL. 'Someday it will be the norm': physician perspectives on the utility of genome sequencing for patient care in the MedSeq Project. Per Med. 2015; 12(1):23-32. PMID: 25642274.
    View in: PubMed
  16. McLaughlin HM, Ceyhan-Birsoy O, Christensen KD, Kohane IS, Krier J, Lane WJ, Lautenbach D, Lebo MS, Machini K, MacRae CA, Azzariti DR, Murray MF, Seidman CE, Vassy JL, Green RC, Rehm HL. A systematic approach to the reporting of medically relevant findings from whole genome sequencing. BMC Med Genet. 2014 Dec 14; 15:134. PMID: 25714468; PMCID: PMC4342199.
  17. Vassy JL, Hivert MF, Dauriz M, Meigs JB. Response to comment on Vassy et al. polygenic type 2 diabetes prediction at the limit of common variant detection. Diabetes 2014;63:2172-2182. Diabetes. 2014 Jul; 63(7):e13. PMID: 24962928.
    View in: PubMed
  18. Walford GA, Porneala BC, Dauriz M, Vassy JL, Cheng S, Rhee EP, Wang TJ, Meigs JB, Gerszten RE, Florez JC. Metabolite traits and genetic risk provide complementary information for the prediction of future type 2 diabetes. Diabetes Care. 2014 Sep; 37(9):2508-14. PMID: 24947790; PMCID: PMC4140156.
  19. Vassy JL, Lautenbach DM, McLaughlin HM, Kong SW, Christensen KD, Krier J, Kohane IS, Feuerman LZ, Blumenthal-Barby J, Roberts JS, Lehmann LS, Ho CY, Ubel PA, MacRae CA, Seidman CE, Murray MF, McGuire AL, Rehm HL, Green RC. The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine. Trials. 2014 Mar 20; 15:85. PMID: 24645908; PMCID: PMC4113228.
  20. Hivert MF, Vassy JL, Meigs JB. Susceptibility to type 2 diabetes mellitus--from genes to prevention. Nat Rev Endocrinol. 2014 Apr; 10(4):198-205. PMID: 24535206; PMCID: PMC4058643.
  21. Vassy JL, Hivert MF, Porneala B, Dauriz M, Florez JC, Dupuis J, Siscovick DS, Fornage M, Rasmussen-Torvik LJ, Bouchard C, Meigs JB. Polygenic type 2 diabetes prediction at the limit of common variant detection. Diabetes. 2014 Jun; 63(6):2172-82. PMID: 24520119; PMCID: PMC4030114.
  22. Raghavan S, Vassy JL. Do physicians think genomic medicine will be useful for patient care? Per Med. 2014; 11(4):424-433. PMID: 26161114.
    View in: PubMed
  23. Vassy JL, Green RC, Lehmann LS. Genomic medicine in primary care: barriers and assets. Postgrad Med J. 2013 Nov; 89(1057):615-6. PMID: 24129030; PMCID: PMC3951755.
  24. Branas CC, Dinardo AR, Puac Polanco VD, Harvey MJ, Vassy JL, Bream K. An exploration of violence, mental health and substance abuse in post-conflict Guatemala. Health (Irvine Calif). 2013 May; 5(5):825-833. PMID: 27818726.
    View in: PubMed
  25. Vassy JL, Donelan K, Hivert MF, Green RC, Grant RW. Genetic susceptibility testing for chronic disease and intention for behavior change in healthy young adults. J Community Genet. 2013 Apr; 4(2):263-71. PMID: 23435806; PMCID: PMC3666830.
  26. Vassy JL. Can genetic information change patient behavior to reduce Type 2 diabetes risk? Per Med. 2013 Jan 01; 10(1). PMID: 24358047.
    View in: PubMed
  27. Vassy JL, Dasmahapatra P, Meigs JB, Schork NJ, Magnussen CG, Chen W, Raitakari OT, Pencina MJ, Jamal SM, Berenson GS, Goodman E. Genotype prediction of adult type 2 diabetes from adolescence in a multiracial population. Pediatrics. 2012 Nov; 130(5):e1235-42. PMID: 23071215; PMCID: PMC3483893.
  28. Vassy JL. Comment on: Alssema et al. One risk assessment tool for cardiovascular disease, type 2 diabetes, and chronic kidney disease. Diabetes Care 2012; 35:741-748. Diabetes Care. 2012 Oct; 35(10):e75. PMID: 22996188; PMCID: PMC3447851.
  29. Grant RW, O'Brien KE, Waxler JL, Vassy JL, Delahanty LM, Bissett LG, Green RC, Stember KG, Guiducci C, Park ER, Florez JC, Meigs JB. Personalized genetic risk counseling to motivate diabetes prevention: a randomized trial. Diabetes Care. 2013 Jan; 36(1):13-9. PMID: 22933432; PMCID: PMC3526219.
  30. Lee Y, Shin H, Vassy JL, Kim JT, Cho SI, Kang SM, Choi SH, Kim KW, Park KS, Jang HC, Lim S. Comparison of regional body composition and its relation with cardiometabolic risk between BMI-matched young and old subjects. Atherosclerosis. 2012 Sep; 224(1):258-65. PMID: 22832005.
    View in: PubMed
  31. Vassy JL, Durant NH, Kabagambe EK, Carnethon MR, Rasmussen-Torvik LJ, Fornage M, Lewis CE, Siscovick DS, Meigs JB. A genotype risk score predicts type 2 diabetes from young adulthood: the CARDIA study. Diabetologia. 2012 Oct; 55(10):2604-2612. PMID: 22782289; PMCID: PMC3434294.
  32. Yoon JW, Kang SM, Vassy JL, Shin H, Lee YH, Ahn HY, Choi SH, Park KS, Jang HC, Lim S. Efficacy and safety of ginsam, a vinegar extract from Panax ginseng, in type 2 diabetic patients: Results of a double-blind, placebo-controlled study. J Diabetes Investig. 2012 Jun 06; 3(3):309-17. PMID: 24843582; PMCID: PMC4014955.
  33. Grimsby JL, Porneala BC, Vassy JL, Yang Q, Florez JC, Dupuis J, Liu T, Yesupriya A, Chang MH, Ned RM, Dowling NF, Khoury MJ, Meigs JB. Race-ethnic differences in the association of genetic loci with HbA1c levels and mortality in U.S. adults: the third National Health and Nutrition Examination Survey (NHANES III). BMC Med Genet. 2012 Apr 27; 13:30. PMID: 22540250; PMCID: PMC3433372.
  34. Vassy JL, Meigs JB. Is genetic testing useful to predict type 2 diabetes? Best Pract Res Clin Endocrinol Metab. 2012 Apr; 26(2):189-201. PMID: 22498248; PMCID: PMC4070012.
  35. Vassy JL, O'Brien KE, Waxler JL, Park ER, Delahanty LM, Florez JC, Meigs JB, Grant RW. Impact of literacy and numeracy on motivation for behavior change after diabetes genetic risk testing. Med Decis Making. 2012 Jul-Aug; 32(4):606-15. PMID: 22247420; PMCID: PMC3683460.
  36. Vassy JL, Shrader P, Yang Q, Liu T, Yesupriya A, Chang MH, Dowling NF, Ned RM, Dupuis J, Florez JC, Khoury MJ, Meigs JB. Genetic associations with metabolic syndrome and its quantitative traits by race/ethnicity in the United States. Metab Syndr Relat Disord. 2011 Dec; 9(6):475-82. PMID: 21848424; PMCID: PMC3225057.
  37. Vassy JL, Shrader P, Jonsson A, Fox CS, Lyssenko V, Isomaa B, Groop L, Meigs JB, Franks PW. Association between parental history of diabetes and type 2 diabetes genetic risk scores in the PPP-Botnia and Framingham Offspring Studies. Diabetes Res Clin Pract. 2011 Aug; 93(2):e76-9. PMID: 21570145; PMCID: PMC3156338.
  38. Vassy JL, Meigs JB. Despite Underestimated Familial Risk by Self-Report, Family History Correlates with Perceived Risk and Worry about Chronic Diseases Such as Coronary Heart Disease and Diabetes. Curr Cardiovasc Risk Rep. 2011 Feb; 5(1):7-9. PMID: 21339842.
    View in: PubMed
  39. Mohan V, Vassy JL, Pradeepa R, Deepa M, Subashini S. The Indian type 2 diabetes risk score also helps identify those at risk of macrovasvular disease and neuropathy (CURES-77). J Assoc Physicians India. 2010 Jul; 58:430-3. PMID: 21121208.
    View in: PubMed
  40. Selvin E, Bolen S, Yeh HC, Wiley C, Wilson LM, Marinopoulos SS, Feldman L, Vassy J, Wilson R, Bass EB, Brancati FL. Cardiovascular outcomes in trials of oral diabetes medications: a systematic review. Arch Intern Med. 2008 Oct 27; 168(19):2070-80. PMID: 18955635; PMCID: PMC2765722.
  41. Bolen S, Feldman L, Vassy J, Wilson L, Yeh HC, Marinopoulos S, Wiley C, Selvin E, Wilson R, Bass EB, Brancati FL. Systematic review: comparative effectiveness and safety of oral medications for type 2 diabetes mellitus. Ann Intern Med. 2007 Sep 18; 147(6):386-99. PMID: 17638715.
    View in: PubMed
  42. Huang HY, Caballero B, Chang S, Alberg AJ, Semba RD, Schneyer C, Wilson RF, Cheng TY, Prokopowicz G, Barnes GJ, Vassy J, Bass EB. Multivitamin/Mineral supplements and prevention of chronic disease: executive summary. Am J Clin Nutr. 2007 Jan; 85(1):265S-268S. PMID: 17209207.
    View in: PubMed
  43. Huang HY, Caballero B, Chang S, Alberg AJ, Semba RD, Schneyer CR, Wilson RF, Cheng TY, Vassy J, Prokopowicz G, Barnes GJ, Bass EB. The efficacy and safety of multivitamin and mineral supplement use to prevent cancer and chronic disease in adults: a systematic review for a National Institutes of Health state-of-the-science conference. Ann Intern Med. 2006 Sep 05; 145(5):372-85. PMID: 16880453.
    View in: PubMed
  44. Huang HY, Caballero B, Chang S, Alberg A, Semba R, Schneyer C, Wilson RF, Cheng TY, Prokopowicz G, Barnes GJ, Vassy J, Bass EB. Multivitamin/mineral supplements and prevention of chronic disease. Evid Rep Technol Assess (Full Rep). 2006 May; (139):1-117. PMID: 17764205; PMCID: PMC4781083.
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