Harvard Catalyst Profiles

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Jason Lyell Vassy, M.D.

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Overview

Mentoring
Available: 06/01/23, Expires: 05/31/25

Our Genomes2Veteran Research Program (https://www.genomes2people.org/research/genomes2veterans/) studies how doctors and patients use genetic and genomic information to improve patient healthcare and health outcomes. Our research integrates genetic or genomic information into the real-world practice of medicine, including primary care settings. Current ongoing studies include a randomized controlled trial of polygenic risk scores for common diseases such as type 2 diabetes and colorectal cancer and a second large trial of precision prostate cancer screening. We are also leading the Million Veteran Program Return Of Actionable Results (MVP-ROAR) Study, in which MVP study participants across the country are being recontacted and invited to learn more about potentially clinically actionable genetic results identified in their study data (https://www.mvp.va.gov/pwa/). We collaborate widely across the larger Harvard community, including Brigham and Women's Hospital, Ariadne Labs, and the Broad Institute. Students have multiple opportunities to engage in all aspects of outcomes research and lead independent projects potentially resulting in presentation or publication.


Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. I01CX002635 (VASSY, JASON L) Oct 1, 2023 - Sep 30, 2028
    NIH
    The Prostate Cancer, Genetic Risk, and Equitable Screening Study (ProGRESS): A pragmatic trial of precision prostate cancer screening
    Role: Principal Investigator
  2. I01HX003627 (CLAYMAN, MARLA L.) Oct 1, 2023 - Sep 30, 2026
    NIH
    Building a shared decision making implementation strategy for the emerging paradigm of precision cancer screening
    Role: Co-Principal Investigator
  3. R35HG010706 (VASSY, JASON L) Sep 1, 2019 - Jun 30, 2024
    NIH
    Pragmatic randomized trial of polygenic risk scoring for common diseases in primary care
    Role: Principal Investigator
  4. IK2CX001262 (VASSY, JASON L) Jan 1, 2016 - Dec 31, 2020
    NIH
    Clinical safety and efficacy of pharmacogenetics in Veteran care
    Role: Principal Investigator

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.