Harvard Catalyst Profiles

Our Genomes2Veteran Research Program (https://www.genomes2people.org/research/genomes2veterans/) studies how doctors and patients use genetic and genomic information to improve patient healthcare and health outcomes. Our research integrates genetic or genomic information into the real-world practice of medicine, including primary care settings. Current ongoing studies include a randomized controlled trial of polygenic risk scores for common diseases such as type 2 diabetes and colorectal cancer and a second large trial of precision prostate cancer screening. We are also leading the Million Veteran Program Return Of Actionable Results (MVP-ROAR) Study, in which MVP study participants across the country are being recontacted and invited to learn more about potentially clinically actionable genetic results identified in their study data (https://www.mvp.va.gov/pwa/). We collaborate widely across the larger Harvard community, including Brigham and Women's Hospital, Ariadne Labs, and the Broad Institute. Students have multiple opportunities to engage in all aspects of outcomes research and lead independent projects potentially resulting in presentation or publication.