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Jason Lyell Vassy, M.D.

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Other Positions


Available: 04/05/22, Expires: 06/01/23

Our team conducts clinical research to study the process and outcomes of integrating genetic or genomic information into the real-world practice of medicine. Current ongoing studies include a randomized controlled trial of polygenic risk scores for common diseases such as type 2 diabetes and prostate cancer. We are also leading the Million Veteran Program Return Of Actionable Results (MVP-ROAR) Study, in which MVP study participants across the country are being recontacted and invited to learn more about potentially clinically actionable genetic results identified in their study data.

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R35HG010706 (VASSY, JASON L) Sep 1, 2019 - Jun 30, 2024
    Pragmatic randomized trial of polygenic risk scoring for common diseases in primary care
    Role: Principal Investigator
  2. IK2CX001262 (VASSY, JASON L) Jan 1, 2016 - Dec 31, 2020
    Clinical safety and efficacy of pharmacogenetics in Veteran care
    Role: Principal Investigator

Featured Content

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lewis ACF, Perez EF, Prince AER, Flaxman HR, Gomez L, Brockman DG, Chandler PD, Kerman BJ, Lebo MS, Smoller JW, Weiss ST, Blout Zawatksy CL, Meigs JB, Green RC, Vassy JL, Karlson EW. Patient and provider perspectives on polygenic risk scores: implications for clinical reporting and utilization. Genome Med. 2022 10 07; 14(1):114. PMID: 36207733; PMCID: PMC9540716.
    Citations:    Fields:    Translation:Humans
  2. Alexander NVJ, Brunette CA, Guardino ET, Yi T, Kerman BJ, MacIsaac K, Harris EJ, Antwi AA, Vassy JL. Performance of EHR classifiers for patient eligibility in a clinical trial of precision screening. Contemp Clin Trials. 2022 Oct; 121:106926. PMID: 36115637.
    Citations:    Fields:    Translation:Humans
  3. Oslin DW, Lynch KG, Shih MC, Ingram EP, Wray LO, Chapman SR, Kranzler HR, Gelernter J, Pyne JM, Stone A, DuVall SL, Lehmann LS, Thase ME, Aslam M, Batki SL, Bjork JM, Blow FC, Brenner LA, Chen P, Desai S, Dieperink EW, Fears SC, Fuller MA, Goodman CS, Graham DP, Haas GL, Hamner MB, Helstrom AW, Hurley RA, Icardi MS, Jurjus GJ, Kilbourne AM, Kreyenbuhl J, Lache DJ, Lieske SP, Lynch JA, Meyer LJ, Montalvo C, Muralidhar S, Ostacher MJ, Paschall GY, Pfeiffer PN, Prieto S, Przygodzki RM, Ranganathan M, Rodriguez-Suarez MM, Roggenkamp H, Schichman SA, Schneeweis JS, Simonetti JA, Steinhauer SR, Suppes T, Umbert MA, Vassy JL, Voora D, Wiechers IR, Wood AE. Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder: The PRIME Care Randomized Clinical Trial. JAMA. 2022 07 12; 328(2):151-161. PMID: 35819423; PMCID: PMC9277497.
    Citations:    Fields:    Translation:Humans
  4. Hao L, Kraft P, Berriz GF, Hynes ED, Koch C, Korategere V Kumar P, Parpattedar SS, Steeves M, Yu W, Antwi AA, Brunette CA, Danowski M, Gala MK, Green RC, Jones NE, Lewis ACF, Lubitz SA, Natarajan P, Vassy JL, Lebo MS. Development of a clinical polygenic risk score assay and reporting workflow. Nat Med. 2022 05; 28(5):1006-1013. PMID: 35437332; PMCID: PMC9117136.
    Citations:    Fields:    Translation:Humans
  5. Lu B, Posner D, Vassy JL, Ho YL, Galloway A, Raghavan S, Honerlaw J, Tarko L, Russo J, Qazi S, Orkaby AR, Tanukonda V, Djousse L, Gaziano JM, Gagnon DR, Cho K, Wilson PWF. Prediction of Cardiovascular and All-Cause Mortality After Myocardial Infarction in US Veterans. Am J Cardiol. 2022 04 15; 169:10-17. PMID: 35063273.
    Citations: 1     Fields:    Translation:Humans
  6. Brunette CA, Dong OM, Vassy JL, Danowski ME, Alexander N, Antwi AA, Christensen KD. A Cost-Consequence Analysis of Preemptive SLCO1B1 Testing for Statin Myopathy Risk Compared to Usual Care. J Pers Med. 2021 Oct 31; 11(11). PMID: 34834475; PMCID: PMC8624003.
  7. Dong OM, Roberts MC, Wu RR, Voils CI, Sperber N, Gavin KL, Bates J, Chanfreau-Coffinier C, Naglich M, Kelley MJ, Vassy JL, Sriram P, Heise CW, Rivas S, Ribeiro M, Chapman JG, Voora D. Evaluation of the Veterans Affairs Pharmacogenomic Testing for Veterans (PHASER) clinical program at initial test sites. Pharmacogenomics. 2021 11; 22(17):1121-1133. PMID: 34704830; PMCID: PMC8592066.
    Citations:    Fields:    Translation:Humans
  8. Lewis ACF, Green RC, Vassy JL. Polygenic risk scores in the clinic: Translating risk into action. HGG Adv. 2021 Oct 14; 2(4):100047. PMID: 35047839; PMCID: PMC8756548.
    Citations: 3     
  9. Brunette CA, Vassy JL. The role of SLCO1B1 genotyping in lowering cardiovascular risk. Pharmacogenomics. 2021 07; 22(11):649-656. PMID: 34196599.
    Citations:    Fields:    Translation:Humans
  10. Tian L, Vassy JL, Ritchie CS, Lee CC, Kim DH. How to Quantify and Interpret Treatment Effects in Comparative Clinical Studies of COVID-19. Ann Intern Med. 2021 05; 174(5):731-732. PMID: 33999681.
    Citations:    Fields:    Translation:HumansCells
  11. Ho YL, Nguyen XT, Yan JQ, Vassy JL, Gagnon DR, Gaziano JM, Wilson PW, Cho K, Djoussé L. Chocolate consumption and risk of coronary artery disease: the Million Veteran Program. Am J Clin Nutr. 2021 05; 113(5):1137-1144. PMID: 34483344; PMCID: PMC8412179.
    Citations: 2     Fields:    Translation:Humans
  12. Dong OM, Bates J, Chanfreau-Coffinier C, Naglich M, Kelley MJ, Meyer LJ, Icardi M, Vassy JL, Sriram P, Heise CW, Rivas S, Ribeiro M, Jacobitz R, Rozelle S, Chapman JG, Voora D. Veterans Affairs Pharmacogenomic Testing for Veterans (PHASER) clinical program. Pharmacogenomics. 2021 02; 22(3):137-144. PMID: 33403869.
    Citations: 4     Fields:    Translation:Humans
  13. Vassy JL, Gaziano JM, Green RC, Ferguson RE, Advani S, Miller SJ, Chun S, Hage AK, Seo SJ, Majahalme N, MacMullen L, Zimolzak AJ, Brunette CA. Effect of Pharmacogenetic Testing for Statin Myopathy Risk vs Usual Care on Blood Cholesterol: A Randomized Clinical Trial. JAMA Netw Open. 2020 12 01; 3(12):e2027092. PMID: 33270123; PMCID: PMC7716196.
    Citations: 4     Fields:    Translation:Humans
  14. Smetana GW, Vassy JL, Hofstatter E, Libman H. Should You Recommend Direct-to-Consumer Genetic Testing for This Patient? : Grand Rounds Discussion From Beth Israel Deaconess Medical Center. Ann Intern Med. 2020 10 06; 173(7):563-571. PMID: 33017547.
    Citations:    Fields:    Translation:Humans
  15. Hull LE, Vassy JL, Stone A, Chanfreau-Coffinier CC, Heise CW, Pratt VM, Przygodzki R, Voils CI, Voora D, Wang-Rodriguez J, Schichman SA, Scheuner MT. Identifying End Users' Preferences about Structuring Pharmacogenetic Test Orders in an Electronic Health Record System. J Mol Diagn. 2020 10; 22(10):1264-1271. PMID: 32980074.
    Citations:    Fields:    Translation:Humans
  16. Raghavan S, Ho YL, Vassy JL, Posner D, Honerlaw J, Costa L, Phillips LS, Gagnon DR, Wilson PWF, Cho K. Optimizing Atherosclerotic Cardiovascular Disease Risk Estimation for Veterans With Diabetes Mellitus. Circ Cardiovasc Qual Outcomes. 2020 Aug 31; CIRCOUTCOMES120006528. PMID: 32862698; PMCID: PMC7914289.
    Citations:    Fields:    
  17. McCaw ZR, Tian L, Vassy JL, Ritchie CS, Lee CC, Kim DH, Wei LJ. How to Quantify and Interpret Treatment Effects in Comparative Clinical Studies of COVID-19. Ann Intern Med. 2020 10 20; 173(8):632-637. PMID: 32634024; PMCID: PMC7350552.
    Citations: 13     Fields:    Translation:HumansCellsPHPublic Health
  18. Orkaby AR, Driver JA, Ho YL, Lu B, Costa L, Honerlaw J, Galloway A, Vassy JL, Forman DE, Gaziano JM, Gagnon DR, Wilson PWF, Cho K, Djousse L. Association of Statin Use With All-Cause and Cardiovascular Mortality in US Veterans 75 Years and Older. JAMA. 2020 07 07; 324(1):68-78. PMID: 32633800; PMCID: PMC7341181.
    Citations: 30     Fields:    Translation:Humans
  19. Vassy JL, Lu B, Ho YL, Galloway A, Raghavan S, Honerlaw J, Tarko L, Russo J, Qazi S, Orkaby AR, Tanukonda V, Djousse L, Gaziano JM, Gagnon DR, Cho K, Wilson PWF. Estimation of Atherosclerotic Cardiovascular Disease Risk Among Patients in the Veterans Affairs Health Care System. JAMA Netw Open. 2020 07 01; 3(7):e208236. PMID: 32662843; PMCID: PMC7361654.
    Citations: 5     Fields:    Translation:Humans
  20. Wu P, Rybin D, Bielak LF, Feitosa MF, Franceschini N, Li Y, Lu Y, Marten J, Musani SK, Noordam R, Raghavan S, Rose LM, Schwander K, Smith AV, Tajuddin SM, Vojinovic D, Amin N, Arnett DK, Bottinger EP, Demirkan A, Florez JC, Ghanbari M, Harris TB, Launer LJ, Liu J, Liu J, Mook-Kanamori DO, Murray AD, Nalls MA, Peyser PA, Uitterlinden AG, Voortman T, Bouchard C, Chasman D, Correa A, de Mutsert R, Evans MK, Gudnason V, Hayward C, Kao L, Kardia SLR, Kooperberg C, Loos RJF, Province MM, Rankinen T, Redline S, Ridker PM, Rotter JI, Siscovick D, Smith BH, van Duijn C, Zonderman AB, Rao DC, Wilson JG, Dupuis J, Meigs JB, Liu CT, Vassy JL. Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose. PLoS One. 2020; 15(5):e0230815. PMID: 32379818; PMCID: PMC7205201.
    Citations: 2     Fields:    Translation:Humans
  21. Brunette CA, Miller SJ, Majahalme N, Hau C, MacMullen L, Advani S, Ludin SA, Zimolzak AJ, Vassy JL. Pragmatic Trials in Genomic Medicine: The Integrating Pharmacogenetics In Clinical Care (I-PICC) Study. Clin Transl Sci. 2020 03; 13(2):381-390. PMID: 31808996; PMCID: PMC7070795.
    Citations: 6     Fields:    Translation:Humans
  22. Hendricks-Sturrup RM, Linsky A, Lu CY, Vassy JL. Genomic testing is best integrated into clinical practice when it is actionable. Per Med. 2020 01; 17(1):5-8. PMID: 31795838.
    Citations: 4     Fields:    Translation:Humans
  23. Raghavan S, Ho YL, Kini V, Rhee MK, Vassy JL, Gagnon DR, Cho K, Wilson PWF, Phillips LS. Association Between Early Hypertension Control and Cardiovascular Disease Incidence in Veterans With Diabetes. Diabetes Care. 2019 10; 42(10):1995-2003. PMID: 31515207; PMCID: PMC6754236.
    Citations:    Fields:    Translation:Humans
  24. Rhee MK, Ho YL, Raghavan S, Vassy JL, Cho K, Gagnon D, Staimez LR, Ford CN, Wilson PWF, Phillips LS. Random plasma glucose predicts the diagnosis of diabetes. PLoS One. 2019; 14(7):e0219964. PMID: 31323063; PMCID: PMC6641200.
    Citations: 8     Fields:    Translation:HumansPHPublic Health
  25. Honerlaw JP, Ho YL, Nguyen XT, Cho K, Vassy JL, Gagnon DR, O'Donnell CJ, Gaziano JM, Wilson PWF, Djousse L. Fried food consumption and risk of coronary artery disease: The Million Veteran Program. Clin Nutr. 2020 04; 39(4):1203-1208. PMID: 31279615.
    Citations: 2     Fields:    Translation:Humans
  26. Hart MR, Biesecker BB, Blout CL, Christensen KD, Amendola LM, Bergstrom KL, Biswas S, Bowling KM, Brothers KB, Conlin LK, Cooper GM, Dulik MC, East KM, Everett JN, Finnila CR, Ghazani AA, Gilmore MJ, Goddard KAB, Jarvik GP, Johnston JJ, Kauffman TL, Kelley WV, Krier JB, Lewis KL, McGuire AL, McMullen C, Ou J, Plon SE, Rehm HL, Richards CS, Romasko EJ, Sagardia AM, Spinner NB, Thompson ML, Turbitt E, Vassy JL, Wilfond BS, Veenstra DL, Berg JS, Green RC, Biesecker LG, Hindorff LA. Correction: Secondary findings from clinical genomic sequencing: prevalence, patient perspectives, family history assessment, and health-care costs from a multisite study. Genet Med. 2019 May; 21(5):1261-1262. PMID: 30670880.
    Citations: 1     Fields:    
  27. Bombard Y, Brothers KB, Fitzgerald-Butt S, Garrison NA, Jamal L, James CA, Jarvik GP, McCormick JB, Nelson TN, Ormond KE, Rehm HL, Richer J, Souzeau E, Vassy JL, Wagner JK, Levy HP. The Responsibility to Recontact Research Participants after Reinterpretation of Genetic and Genomic Research Results. Am J Hum Genet. 2019 04 04; 104(4):578-595. PMID: 30951675; PMCID: PMC6451731.
    Citations: 33     Fields:    Translation:Humans
  28. Ward RE, Cho K, Nguyen XT, Vassy JL, Ho YL, Quaden RM, Gagnon DR, Wilson PWF, Gaziano JM, Djoussé L. Omega-3 supplement use, fish intake, and risk of non-fatal coronary artery disease and ischemic stroke in the Million Veteran Program. Clin Nutr. 2020 02; 39(2):574-579. PMID: 30914216.
    Citations: 2     Fields:    Translation:Humans
  29. McCaw ZR, Vassy JL, Wei LJ. Palbociclib and Fulvestrant in Breast Cancer. N Engl J Med. 2019 02 21; 380(8):796. PMID: 30789681.
    Citations: 1     Fields:    Translation:Humans
  30. Raghavan S, Vassy JL, Ho YL, Song RJ, Gagnon DR, Cho K, Wilson PWF, Phillips LS. Diabetes Mellitus-Related All-Cause and Cardiovascular Mortality in a National Cohort of Adults. J Am Heart Assoc. 2019 02 19; 8(4):e011295. PMID: 30776949; PMCID: PMC6405678.
    Citations: 70     Fields:    Translation:HumansPHPublic Health
  31. Vassy JL, Stone A, Callaghan JT, Mendes M, Meyer LJ, Pratt VM, Przygodzki RM, Scheuner MT, Wang-Rodriguez J, Schichman SA. Response to Gammal et al. Genet Med. 2019 08; 21(8):1888-1889. PMID: 30635623.
    Citations:    Fields:    Translation:Humans
  32. Brothers KB, Vassy JL, Green RC. Reconciling Opportunistic and Population Screening in Clinical Genomics. Mayo Clin Proc. 2019 01; 94(1):103-109. PMID: 30611438; PMCID: PMC6339566.
    Citations: 10     Fields:    Translation:HumansPHPublic Health
  33. Vassy JL. Estimated Filtration: The Continued Need for Expert Classification of Genetic Variants. Ann Intern Med. 2019 01 01; 170(1):64-65. PMID: 30477012.
    Citations:    Fields:    Translation:Humans
  34. Vassy JL, Brunette CA, Majahalme N, Advani S, MacMullen L, Hau C, Zimolzak AJ, Miller SJ. The Integrating Pharmacogenetics in Clinical Care (I-PICC) Study: Protocol for a point-of-care randomized controlled trial of statin pharmacogenetics in primary care. Contemp Clin Trials. 2018 12; 75:40-50. PMID: 30367991.
    Citations: 5     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  35. Vassy JL, Chun S, Advani S, Ludin SA, Smith JG, Alligood EC. Impact of SLCO1B1 Pharmacogenetic Testing on Patient and Healthcare Outcomes: A Systematic Review. Clin Pharmacol Ther. 2019 08; 106(2):360-373. PMID: 30137643; PMCID: PMC8083115.
    Citations: 8     Fields:    Translation:Humans
  36. Imran TF, Posner D, Honerlaw J, Vassy JL, Song RJ, Ho YL, Kittner SJ, Liao KP, Cai T, O'Donnell CJ, Djousse L, Gagnon DR, Gaziano JM, Wilson PW, Cho K. A phenotyping algorithm to identify acute ischemic stroke accurately from a national biobank: the Million Veteran Program. Clin Epidemiol. 2018; 10:1509-1521. PMID: 30425582; PMCID: PMC6201999.
    Citations: 9     
  37. Hart MR, Biesecker BB, Blout CL, Christensen KD, Amendola LM, Bergstrom KL, Biswas S, Bowling KM, Brothers KB, Conlin LK, Cooper GM, Dulik MC, East KM, Everett JN, Finnila CR, Ghazani AA, Gilmore MJ, Goddard KAB, Jarvik GP, Johnston JJ, Kauffman TL, Kelley WV, Krier JB, Lewis KL, McGuire AL, McMullen C, Ou J, Plon SE, Rehm HL, Richards CS, Romasko EJ, Miren Sagardia A, Spinner NB, Thompson ML, Turbitt E, Vassy JL, Wilfond BS, Veenstra DL, Berg JS, Green RC, Biesecker LG, Hindorff LA. Secondary findings from clinical genomic sequencing: prevalence, patient perspectives, family history assessment, and health-care costs from a multisite study. Genet Med. 2019 05; 21(5):1100-1110. PMID: 30287922; PMCID: PMC6450774.
    Citations: 44     Fields:    Translation:Humans
  38. Vassy JL, Stone A, Callaghan JT, Mendes M, Meyer LJ, Pratt VM, Przygodzki RM, Scheuner MT, Wang-Rodriguez J, Schichman SA. Pharmacogenetic testing in the Veterans Health Administration (VHA): policy recommendations from the VHA Clinical Pharmacogenetics Subcommittee. Genet Med. 2019 02; 21(2):382-390. PMID: 29858578; PMCID: PMC6274593.
    Citations: 7     Fields:    Translation:Humans
  39. Vassy JL, Hivert MF, Porneala B, Dauriz M, Florez JC, Dupuis J, Siscovick DS, Fornage M, Rasmussen-Torvik LJ, Bouchard C, Meigs JB. Erratum. Polygenic Type 2 Diabetes Prediction at the Limit of Common Variant Detection. Diabetes 2014;63:2172-2182. Diabetes. 2018 06; 67(6):1206. PMID: 29669744.
    Citations:    Fields:    
  40. Christensen KD, Vassy JL, Phillips KA, Blout CL, Azzariti DR, Lu CY, Robinson JO, Lee K, Douglas MP, Yeh JM, Machini K, Stout NK, Rehm HL, McGuire AL, Green RC, Dukhovny D. Short-term costs of integrating whole-genome sequencing into primary care and cardiology settings: a pilot randomized trial. Genet Med. 2018 12; 20(12):1544-1553. PMID: 29565423; PMCID: PMC6151171.
    Citations: 11     Fields:    Translation:Humans
  41. Vassy JL, Davis JK, Kirby C, Richardson IJ, Green RC, McGuire AL, Ubel PA. How Primary Care Providers Talk to Patients about Genome Sequencing Results: Risk, Rationale, and Recommendation. J Gen Intern Med. 2018 06; 33(6):877-885. PMID: 29374360.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  42. Vassy JL, He W, Florez JC, Meigs JB, Grant RW. Six-Year Diabetes Incidence After Genetic Risk Testing and Counseling: A Randomized Clinical Trial. Diabetes Care. 2018 Mar; 41(3):e25-e26. PMID: 29305403.
    Citations: 3     Fields:    
  43. Vassy JL, Ho YL, Honerlaw J, Cho K, Gaziano JM, Wilson PWF, Gagnon DR. Yield and bias in defining a cohort study baseline from electronic health record data. J Biomed Inform. 2018 02; 78:54-59. PMID: 29305952.
    Citations: 8     Fields:    Translation:Humans
  44. Hull LE, Vassy JL. Toward greater understanding of patient decision-making around genome sequencing. Per Med. 2018 01; 15(1):57-66. PMID: 29714114.
    Citations: 3     Fields:    Translation:Humans
  45. Vassy JL, Christensen KD, Schonman EF, Blout CL, Robinson JO, Krier JB, Diamond PM, Lebo M, Machini K, Azzariti DR, Dukhovny D, Bates DW, MacRae CA, Murray MF, Rehm HL, McGuire AL, Green RC. The Impact of Whole-Genome Sequencing on the Primary Care and Outcomes of Healthy Adult Patients: A Pilot Randomized Trial. Ann Intern Med. 2017 08 01; 167(3):159-169. PMID: 28654958; PMCID: PMC5856654.
    Citations: 66     Fields:    Translation:Humans
  46. Jamal L, Robinson JO, Christensen KD, Blumenthal-Barby J, Slashinski MJ, Perry DL, Vassy JL, Wycliff J, Green RC, McGuire AL. When bins blur: Patient perspectives on categories of results from clinical whole genome sequencing. AJOB Empir Bioeth. 2017 Apr-Jun; 8(2):82-88. PMID: 28949844; PMCID: PMC6647021.
    Citations: 17     Fields:    Translation:Humans
  47. Carere DA, VanderWeele TJ, Vassy JL, van der Wouden CH, Roberts JS, Kraft P, Green RC. Prescription medication changes following direct-to-consumer personal genomic testing: findings from the Impact of Personal Genomics (PGen) Study. Genet Med. 2017 05; 19(5):537-545. PMID: 27657683; PMCID: PMC5362351.
    Citations: 12     Fields:    Translation:Humans
  48. Vassy JL, Bates DW, Murray MF. Appropriateness: A Key to Enabling the Use of Genomics in Clinical Practice? Am J Med. 2016 06; 129(6):551-3. PMID: 26965302; PMCID: PMC5849057.
    Citations: 5     Fields:    Translation:Humans
  49. Lupo PJ, Robinson JO, Diamond PM, Jamal L, Danysh HE, Blumenthal-Barby J, Lehmann LS, Vassy JL, Christensen KD, Green RC, McGuire AL. Patients' perceived utility of whole-genome sequencing for their healthcare: findings from the MedSeq project. Per Med. 2016 Jan 01; 13(1):13-20. PMID: 27019659.
    Citations: 18     Fields:    
  50. Bray MS, Loos RJ, McCaffery JM, Ling C, Franks PW, Weinstock GM, Snyder MP, Vassy JL, Agurs-Collins T. NIH working group report-using genomic information to guide weight management: From universal to precision treatment. Obesity (Silver Spring). 2016 Jan; 24(1):14-22. PMID: 26692578.
    Citations: 39     Fields:    Translation:Humans
  51. Christensen KD, Vassy JL, Jamal L, Lehmann LS, Slashinski MJ, Perry DL, Robinson JO, Blumenthal-Barby J, Feuerman LZ, Murray MF, Green RC, McGuire AL. Are physicians prepared for whole genome sequencing? a qualitative analysis. Clin Genet. 2016 Feb; 89(2):228-34. PMID: 26080898; PMCID: PMC4683111.
    Citations: 61     Fields:    Translation:Humans
  52. Vassy JL, Korf BR, Green RC. How to know when physicians are ready for genomic medicine. Sci Transl Med. 2015 May 13; 7(287):287fs19. PMID: 25971999.
    Citations: 29     Fields:    Translation:Humans
  53. Dauriz M, Porneala BC, Guo X, Bielak LF, Peyser PA, Durant NH, Carnethon MR, Bonadonna RC, Bonora E, Bowden DW, Florez JC, Fornage M, Hivert MF, Jacobs DR, Kabagambe EK, Lewis CE, Murabito JM, Rasmussen-Torvik LJ, Rich SS, Vassy JL, Yao J, Carr JJ, Kardia SL, Siscovick D, O'Donnell CJ, Rotter JI, Dupuis J, Meigs JB. Association of a 62 Variants Type 2 Diabetes Genetic Risk Score With Markers of Subclinical Atherosclerosis: A Transethnic, Multicenter Study. Circ Cardiovasc Genet. 2015 Jun; 8(3):507-15. PMID: 25805414; PMCID: PMC4472563.
    Citations: 8     Fields:    Translation:Humans
  54. Vassy JL, McLaughlin HM, McLaughlin HL, MacRae CA, Seidman CE, Lautenbach D, Krier JB, Lane WJ, Kohane IS, Murray MF, McGuire AL, Rehm HL, Green RC. A one-page summary report of genome sequencing for the healthy adult. Public Health Genomics. 2015; 18(2):123-9. PMID: 25612602.
    Citations: 22     Fields:    Translation:Humans
  55. Vassy JL, Christensen KD, Slashinski MJ, Lautenbach DM, Raghavan S, Robinson JO, Blumenthal-Barby J, Feuerman LZ, Lehmann LS, Murray MF, Green RC, McGuire AL. 'Someday it will be the norm': physician perspectives on the utility of genome sequencing for patient care in the MedSeq Project. Per Med. 2015; 12(1):23-32. PMID: 25642274.
    Citations: 17     Fields:    
  56. McLaughlin HM, Ceyhan-Birsoy O, Christensen KD, Kohane IS, Krier J, Lane WJ, Lautenbach D, Lebo MS, Machini K, MacRae CA, Azzariti DR, Murray MF, Seidman CE, Vassy JL, Green RC, Rehm HL. A systematic approach to the reporting of medically relevant findings from whole genome sequencing. BMC Med Genet. 2014 Dec 14; 15:134. PMID: 25714468; PMCID: PMC4342199.
    Citations: 47     Fields:    Translation:Humans
  57. Vassy JL, Hivert MF, Dauriz M, Meigs JB. Response to comment on Vassy et al. polygenic type 2 diabetes prediction at the limit of common variant detection. Diabetes 2014;63:2172-2182. Diabetes. 2014 Jul; 63(7):e13. PMID: 24962928; PMCID: PMC6463541.
    Citations:    Fields:    Translation:Humans
  58. Walford GA, Porneala BC, Dauriz M, Vassy JL, Cheng S, Rhee EP, Wang TJ, Meigs JB, Gerszten RE, Florez JC. Metabolite traits and genetic risk provide complementary information for the prediction of future type 2 diabetes. Diabetes Care. 2014 Sep; 37(9):2508-14. PMID: 24947790.
    Citations: 38     Fields:    Translation:Humans
  59. Vassy JL, Lautenbach DM, McLaughlin HM, Kong SW, Christensen KD, Krier J, Kohane IS, Feuerman LZ, Blumenthal-Barby J, Roberts JS, Lehmann LS, Ho CY, Ubel PA, MacRae CA, Seidman CE, Murray MF, McGuire AL, Rehm HL, Green RC. The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine. Trials. 2014 Mar 20; 15:85. PMID: 24645908.
    Citations: 78     Fields:    Translation:Humans
  60. Hivert MF, Vassy JL, Meigs JB. Susceptibility to type 2 diabetes mellitus--from genes to prevention. Nat Rev Endocrinol. 2014 Apr; 10(4):198-205. PMID: 24535206; PMCID: PMC4058643.
    Citations: 24     Fields:    Translation:Humans
  61. Vassy JL, Hivert MF, Porneala B, Dauriz M, Florez JC, Dupuis J, Siscovick DS, Fornage M, Rasmussen-Torvik LJ, Bouchard C, Meigs JB. Polygenic type 2 diabetes prediction at the limit of common variant detection. Diabetes. 2014 Jun; 63(6):2172-82. PMID: 24520119; PMCID: PMC4030114.
    Citations: 66     Fields:    Translation:HumansPHPublic Health
  62. Raghavan S, Vassy JL. Do physicians think genomic medicine will be useful for patient care? Per Med. 2014; 11(4):424-433. PMID: 26161114; PMCID: PMC4494677.
    Citations: 11     Fields:    
  63. Vassy JL, Green RC, Lehmann LS. Genomic medicine in primary care: barriers and assets. Postgrad Med J. 2013 Nov; 89(1057):615-6. PMID: 24129030.
    Citations: 6     Fields:    Translation:Humans
  64. Branas CC, Dinardo AR, Puac Polanco VD, Harvey MJ, Vassy JL, Bream K. An exploration of violence, mental health and substance abuse in post-conflict Guatemala. Health (Irvine Calif). 2013 May; 5(5):825-833. PMID: 27818726; PMCID: PMC5095616.
    Citations: 7     
  65. Vassy JL, Donelan K, Hivert MF, Green RC, Grant RW. Genetic susceptibility testing for chronic disease and intention for behavior change in healthy young adults. J Community Genet. 2013 Apr; 4(2):263-71. PMID: 23435806.
    Citations: 9     
  66. Vassy JL. Can genetic information change patient behavior to reduce Type 2 diabetes risk? Per Med. 2013 Jan 01; 10(1). PMID: 24358047.
    Citations: 4     Fields:    
  67. Vassy JL, Dasmahapatra P, Meigs JB, Schork NJ, Magnussen CG, Chen W, Raitakari OT, Pencina MJ, Jamal SM, Berenson GS, Goodman E. Genotype prediction of adult type 2 diabetes from adolescence in a multiracial population. Pediatrics. 2012 Nov; 130(5):e1235-42. PMID: 23071215; PMCID: PMC3483893.
    Citations: 27     Fields:    Translation:Humans
  68. Vassy JL. Comment on: Alssema et al. One risk assessment tool for cardiovascular disease, type 2 diabetes, and chronic kidney disease. Diabetes Care 2012; 35:741-748. Diabetes Care. 2012 Oct; 35(10):e75. PMID: 22996188.
    Citations:    Fields:    Translation:Humans
  69. Grant RW, O'Brien KE, Waxler JL, Vassy JL, Delahanty LM, Bissett LG, Green RC, Stember KG, Guiducci C, Park ER, Florez JC, Meigs JB. Personalized genetic risk counseling to motivate diabetes prevention: a randomized trial. Diabetes Care. 2013 Jan; 36(1):13-9. PMID: 22933432.
    Citations: 66     Fields:    Translation:Humans
  70. Lee Y, Shin H, Vassy JL, Kim JT, Cho SI, Kang SM, Choi SH, Kim KW, Park KS, Jang HC, Lim S. Comparison of regional body composition and its relation with cardiometabolic risk between BMI-matched young and old subjects. Atherosclerosis. 2012 Sep; 224(1):258-65. PMID: 22832005.
    Citations: 8     Fields:    Translation:Humans
  71. Vassy JL, Durant NH, Kabagambe EK, Carnethon MR, Rasmussen-Torvik LJ, Fornage M, Lewis CE, Siscovick DS, Meigs JB. A genotype risk score predicts type 2 diabetes from young adulthood: the CARDIA study. Diabetologia. 2012 Oct; 55(10):2604-2612. PMID: 22782289; PMCID: PMC3434294.
    Citations: 32     Fields:    Translation:Humans
  72. Yoon JW, Kang SM, Vassy JL, Shin H, Lee YH, Ahn HY, Choi SH, Park KS, Jang HC, Lim S. Efficacy and safety of ginsam, a vinegar extract from Panax ginseng, in type 2 diabetic patients: Results of a double-blind, placebo-controlled study. J Diabetes Investig. 2012 Jun 06; 3(3):309-17. PMID: 24843582.
    Citations: 12     Fields:    
  73. Grimsby JL, Porneala BC, Vassy JL, Yang Q, Florez JC, Dupuis J, Liu T, Yesupriya A, Chang MH, Ned RM, Dowling NF, Khoury MJ, Meigs JB. Race-ethnic differences in the association of genetic loci with HbA1c levels and mortality in U.S. adults: the third National Health and Nutrition Examination Survey (NHANES III). BMC Med Genet. 2012 Apr 27; 13:30. PMID: 22540250; PMCID: PMC3433372.
    Citations: 19     Fields:    Translation:Humans
  74. Vassy JL, Meigs JB. Is genetic testing useful to predict type 2 diabetes? Best Pract Res Clin Endocrinol Metab. 2012 Apr; 26(2):189-201. PMID: 22498248; PMCID: PMC4070012.
    Citations: 28     Fields:    Translation:Humans
  75. Vassy JL, O'Brien KE, Waxler JL, Park ER, Delahanty LM, Florez JC, Meigs JB, Grant RW. Impact of literacy and numeracy on motivation for behavior change after diabetes genetic risk testing. Med Decis Making. 2012 Jul-Aug; 32(4):606-15. PMID: 22247420.
    Citations: 21     Fields:    Translation:Humans
  76. Vassy JL, Shrader P, Yang Q, Liu T, Yesupriya A, Chang MH, Dowling NF, Ned RM, Dupuis J, Florez JC, Khoury MJ, Meigs JB. Genetic associations with metabolic syndrome and its quantitative traits by race/ethnicity in the United States. Metab Syndr Relat Disord. 2011 Dec; 9(6):475-82. PMID: 21848424; PMCID: PMC3225057.
    Citations: 5     Fields:    Translation:Humans
  77. Vassy JL, Shrader P, Jonsson A, Fox CS, Lyssenko V, Isomaa B, Groop L, Meigs JB, Franks PW. Association between parental history of diabetes and type 2 diabetes genetic risk scores in the PPP-Botnia and Framingham Offspring Studies. Diabetes Res Clin Pract. 2011 Aug; 93(2):e76-e79. PMID: 21570145.
    Citations: 13     Fields:    Translation:Humans
  78. Vassy JL, Meigs JB. Despite Underestimated Familial Risk by Self-Report, Family History Correlates with Perceived Risk and Worry about Chronic Diseases Such as Coronary Heart Disease and Diabetes. Curr Cardiovasc Risk Rep. 2011 Feb; 5(1):7-9. PMID: 21339842.
    Citations: 2     
  79. Mohan V, Vassy JL, Pradeepa R, Deepa M, Subashini S. The Indian type 2 diabetes risk score also helps identify those at risk of macrovasvular disease and neuropathy (CURES-77). J Assoc Physicians India. 2010 Jul; 58:430-3. PMID: 21121208.
    Citations: 4     Fields:    Translation:Humans
  80. Selvin E, Bolen S, Yeh HC, Wiley C, Wilson LM, Marinopoulos SS, Feldman L, Vassy J, Wilson R, Bass EB, Brancati FL. Cardiovascular outcomes in trials of oral diabetes medications: a systematic review. Arch Intern Med. 2008 Oct 27; 168(19):2070-80. PMID: 18955635; PMCID: PMC2765722.
    Citations: 95     Fields:    Translation:Humans
  81. Bolen S, Feldman L, Vassy J, Wilson L, Yeh HC, Marinopoulos S, Wiley C, Selvin E, Wilson R, Bass EB, Brancati FL. Systematic review: comparative effectiveness and safety of oral medications for type 2 diabetes mellitus. Ann Intern Med. 2007 Sep 18; 147(6):386-99. PMID: 17638715.
    Citations: 191     Fields:    Translation:Humans
  82. Huang HY, Caballero B, Chang S, Alberg AJ, Semba RD, Schneyer C, Wilson RF, Cheng TY, Prokopowicz G, Barnes GJ, Vassy J, Bass EB. Multivitamin/Mineral supplements and prevention of chronic disease: executive summary. Am J Clin Nutr. 2007 Jan; 85(1):265S-268S. PMID: 17209207.
    Citations: 7     Fields:    Translation:HumansPHPublic Health
  83. Huang HY, Caballero B, Chang S, Alberg AJ, Semba RD, Schneyer CR, Wilson RF, Cheng TY, Vassy J, Prokopowicz G, Barnes GJ, Bass EB. The efficacy and safety of multivitamin and mineral supplement use to prevent cancer and chronic disease in adults: a systematic review for a National Institutes of Health state-of-the-science conference. Ann Intern Med. 2006 Sep 05; 145(5):372-85. PMID: 16880453.
    Citations: 62     Fields:    Translation:HumansPHPublic Health
  84. Huang HY, Caballero B, Chang S, Alberg A, Semba R, Schneyer C, Wilson RF, Cheng TY, Prokopowicz G, Barnes GJ, Vassy J, Bass EB. Multivitamin/mineral supplements and prevention of chronic disease. Evid Rep Technol Assess (Full Rep). 2006 May; (139):1-117. PMID: 17764205.
    Citations: 14     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.