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profileRaymond Taeyong Chung, M.D.

TitleAssociate Professor of Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
WRN 1007C, GI Unit
55 Fruit St
Boston MA 02114
Phone617/724-7562
Fax617/643-0446
vCardDownload vCard (login for email)

Collapse Mentoring 
Collapse current student opportunities
Available: 07/27/17, Expires: 07/26/18

The MGH Gastroenterology Division and NIDDK are offering one-year NIH-funded Pre-doctoral Research Fellowships at MGH for post-baccalaureate students enrolled in a program leading to a Ph.D. in science or in an equivalent research doctoral degree program or health-professional students, graduate students in the quantitative sciences, or individuals in postgraduate clinical training who wish to interrupt their studies for a year or more to engage in full-time research training before competing their formal training programs. This is an ideal opportunity for students interested in exploring fundamental, translational, or clinical research in gastrointestinal and liver diseases as a possible career. Those accepted will engage in a hands-on research project under the mentorship of a leading investigator within the GI Division at MGH. A stipend is provided. Funds to support attendance at national meetings are also provided. Applications will be accepted on a rolling basis with the planned Fellowship year to begin after July 2014, based on arrangements with the mentor.

The individual to be trained must be a citizen or a noncitizen national of the United States or have been lawfully admitted for permanent residence at the time of appointment. All trainees are required to pursue their research training full time, normally defined as 40 hours per week, or as specified by the sponsoring institution in accordance with its own policies. Appointments are normally made in 12-month increments, and no less than 9 months. Additional details on citizenship, training period, and aggregate duration of support are available in the NIH Grants Policy Statement.

Students from underrepresented minority groups are strongly encouraged to apply. Additional information is available by contacting Dr. Raymond Chung at rtchung@partners.org (telephone 617-724-7562).

Collapse completed student projects
Evaluating the Prognostic Power of Three SNP Loci for Patients with Early Chronic Hepatitis C
Summer, 06/12/14 - 08/01/14
Retrospective Review of Acetaminophen/ Diphenhydramine Overdose: Toxicity Features and Outcomes Reported to California Poison Control System Over 15 Years
Summer, 06/23/14 - 08/11/14
Pilot Protocol of Antiviral Prophylaxis Against HIV Recurrence in Orthotopic Liver Transplantation Recipients PASTEUR
Part Time/Continuation, 01/01/02 - 03/01/02
The Liver Health Project - Addressing Hepatitis B Infections in Boston
Community Service, 05/01/10 - 05/07/11
The Role of Intermittent Hypoxia in the Pathogenesis of Non-Alcoholic Fatty Liver Disease
Summer, 06/15/15 - 08/14/15
Investigation of the Effect of Hepatitis C Virus Infection on Serum Cholesterol Levels
Summer, 06/18/07 - 08/10/07
Effects of n-acetylcysteine on clinical outcomes in acute liver failure
Summer, 06/16/08 - 08/11/08
Analysis of the Quasispecies Diversity of Hepatitis C Infection in HIV Co-infected Patients Undergoing Highly Active Antiretroviral Therapy PASTEUR
Summer, 06/26/00 - 08/18/00
Pilot Protocol of Antiviral Prophylaxis Against HIV Recurrence in Orthotopic Liver Transplantation Recipients PASTEUR
Part Time/Continuation, 09/17/01 - 12/21/01
A Preliminary Trial of Oral Ribavirin to Reduce the Frequency of Liver Allograft Rejection in Subjects Undergoing Transplant for Hepatitis C-related Cirrhosis PASTEUR
Summer, 06/25/01 - 08/17/01

Collapse Research 
Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R01DK108370     (CHUNG, RAYMOND T)Sep 23, 2015 - Aug 31, 2020
NIH/NIDDK
HIV-Associated Macrophage Alterations and Progressive Liver Disease
Role: Principal Investigator

R43AA023707     (PATEL, SURAJ J)Sep 20, 2014 - Aug 31, 2015
NIH/NIAAA
Development of Gap Junction Inhibition Therapy for Alcoholic Liver Disease
Role: Principal Investigator

R01DK098079     (CHUNG, RAYMOND T)Sep 1, 2013 - Aug 31, 2017
NIH/NIDDK
HIV-Hepatitis C Virus Cooperative Interactions and Liver Disease Progression
Role: Principal Investigator

R56DK098079     (CHUNG, RAYMOND T)Sep 24, 2012 - Aug 31, 2013
NIH/NIDDK
HIV-Hepatitis C Virus Cooperative Interactions and Liver Disease Progression
Role: Principal Investigator

R01DA033541     (CHUNG, RAYMOND T)Sep 15, 2011 - Aug 31, 2016
NIH/NIDA
Discovery and Assessment of Genetic Determinants of HCV and HIV Control
Role: Principal Investigator

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Samur S, Bethea ED, Chung RT, Chhatwal J. Cost-effectiveness of pre- vs post-liver transplant hepatitis C treatment: Robustness of results. Clin Gastroenterol Hepatol. 2017 Aug 29. PMID: 28864272.
    View in: PubMed
  2. Colpitts CC, Chung RT, Baumert TF. Entry Inhibitors: A Perspective for Prevention of Hepatitis C Virus Infection in Organ Transplantation. ACS Infect Dis. 2017 Sep 08; 3(9):620-623. PMID: 28812869.
    View in: PubMed
  3. Simon TG, Bamira DG, Chung RT, Weiner RB, Corey KE. Nonalcoholic Steatohepatitis is Associated with Cardiac Remodeling and Dysfunction. Obesity (Silver Spring). 2017 Aug; 25(8):1313-1316. PMID: 28745025.
    View in: PubMed
  4. Chhatwal J, Samur S, Bethea E, Chung RT. Reply. Hepatology. 2017 Sep; 66(3):1005-1006. PMID: 28586089.
    View in: PubMed
  5. Rosen HR, Ghany MG, Chung RT, Lok ASF. NAM 2017 report: A national plan to eliminate hepatitis B and C in the United States by 2030 and the AASLD's response. Hepatology. 2017 Jul 17. PMID: 28714210.
    View in: PubMed
  6. Lok AS, Chung RT, Vargas HE, Kim AY, Naggie S, Powderly WG. Comments on cochrane review on direct-acting antivirals for hepatitis C. Hepatology. 2017 Jul 16. PMID: 28714142.
    View in: PubMed
  7. Goossens N, Singal AG, King LY, Andersson KL, Fuchs BC, Besa C, Taouli B, Chung RT, Hoshida Y. Cost-Effectiveness of Risk Score-Stratified Hepatocellular Carcinoma Screening in Patients with Cirrhosis. Clin Transl Gastroenterol. 2017 Jun 22; 8(6):e101. PMID: 28640287.
    View in: PubMed
  8. Hogan JJ, Lim MA, Palmer MB, Bloom RD, Chung RT, Sise ME. Development of proteinuria and focal segmental glomerulosclerosis during direct-acting antiviral therapy for hepatitis C virus infection. Hepatology. 2017 Aug; 66(2):658-660. PMID: 28211090.
    View in: PubMed
  9. Samur S, Kues B, Ayer T, Roberts MS, Kanwal F, Hur C, Donnell DMS, Chung RT, Chhatwal J. Cost Effectiveness of Pre- vs Post-Liver Transplant Hepatitis C Treatment With Direct-Acting Antivirals. Clin Gastroenterol Hepatol. 2017 Jun 17. PMID: 28634131.
    View in: PubMed
  10. Holmes JA, Yu ML, Chung RT. Hepatitis B reactivation during or after direct acting antiviral therapy - implication for susceptible individuals. Expert Opin Drug Saf. 2017 Jun; 16(6):651-672. PMID: 28471314.
    View in: PubMed
  11. Tsai WL, Cheng JS, Shu CW, Lai KH, Chan HH, Wu CC, Wu JM, Hsu PI, Chung RT, Chang TH. Asunaprevir Evokes Hepatocytes Innate Immunity to Restrict the Replication of Hepatitis C and Dengue Virus. Front Microbiol. 2017; 8:668. PMID: 28473813.
    View in: PubMed
  12. Naggie S, Marks KM, Hughes M, Fierer DS, Macbrayne C, Kim A, Hollabaugh K, Roa J, Symonds B, Brainard DM, McHutchison JG, Peters MG, Kiser JJ, Chung R. Sofosbuvir Plus Ribavirin Without Interferon for Treatment of Acute Hepatitis C Virus Infection in HIV-1-Infected Individuals: SWIFT-C. Clin Infect Dis. 2017 04 15; 64(8):1035-1042. PMID: 28329053.
    View in: PubMed
  13. Dhyani M, Grajo JR, Bhan AK, Corey K, Chung R, Samir AE. Validation of Shear Wave Elastography Cutoff Values on the Supersonic Aixplorer for Practical Clinical Use in Liver Fibrosis Staging. Ultrasound Med Biol. 2017 Jun; 43(6):1125-1133. PMID: 28341490.
    View in: PubMed
  14. Chen JY, Newcomb B, Zhou C, Pondick JV, Ghoshal S, York SR, Motola DL, Coant N, Yi JK, Mao C, Tanabe KK, Bronova I, Berdyshev EV, Fuchs BC, Hannun Y, Chung RT, Mullen AC. Tricyclic Antidepressants Promote Ceramide Accumulation to Regulate Collagen Production in Human Hepatic Stellate Cells. Sci Rep. 2017 Mar 21; 7:44867. PMID: 28322247.
    View in: PubMed
  15. Chan J, Chung RT. Perspectives on HCV: Current Therapeutic Regimens and Drug-Drug Interactions. Clin Pharmacol Drug Dev. 2017 Mar; 6(2):147-163. PMID: 28263458.
    View in: PubMed
  16. Klebanoff MJ, Corey KE, Chhatwal J, Kaplan LM, Chung RT, Hur C. Bariatric surgery for nonalcoholic steatohepatitis: A clinical and cost-effectiveness analysis. Hepatology. 2017 Apr; 65(4):1156-1164. PMID: 27880977.
    View in: PubMed
  17. Fusco DN, Pratt H, Kandilas S, Cheon SS, Lin W, Cronkite DA, Basavappa M, Jeffrey KL, Anselmo A, Sadreyev R, Yapp C, Shi X, O'Sullivan JF, Gerszten RE, Tomaru T, Yoshino S, Satoh T, Chung RT. HELZ2 Is an IFN Effector Mediating Suppression of Dengue Virus. Front Microbiol. 2017; 8:240. PMID: 28265266.
    View in: PubMed
  18. Davis BC, Tillman H, Chung RT, Stravitz RT, Reddy R, Fontana RJ, McGuire B, Davern T, Lee WM. Heat stroke leading to acute liver injury & failure: A case series from the Acute Liver Failure Study Group. Liver Int. 2017 Apr; 37(4):509-513. PMID: 28128878.
    View in: PubMed
  19. Kalinich M, Bhan I, Kwan TT, Miyamoto DT, Javaid S, LiCausi JA, Milner JD, Hong X, Goyal L, Sil S, Choz M, Ho U, Kapur R, Muzikansky A, Zhang H, Weitz DA, Sequist LV, Ryan DP, Chung RT, Zhu AX, Isselbacher KJ, Ting DT, Toner M, Maheswaran S, Haber DA. An RNA-based signature enables high specificity detection of circulating tumor cells in hepatocellular carcinoma. Proc Natl Acad Sci U S A. 2017 Jan 31; 114(5):1123-1128. PMID: 28096363.
    View in: PubMed
  20. Chhatwal J, Samur S, Kues B, Ayer T, Roberts MS, Kanwal F, Hur C, Donnell DM, Chung RT. Optimal timing of hepatitis C treatment for patients on the liver transplant waiting list. Hepatology. 2017 Mar; 65(3):777-788. PMID: 27906468.
    View in: PubMed
  21. Bility MT, Nio K, Li F, McGivern DR, Lemon SM, Feeney ER, Chung RT, Su L. Chronic hepatitis C infection-induced liver fibrogenesis is associated with M2 macrophage activation. Sci Rep. 2016 Dec 21; 6:39520. PMID: 28000758.
    View in: PubMed
  22. Nakagawa S, Wei L, Song WM, Higashi T, Ghoshal S, Kim RS, Bian CB, Yamada S, Sun X, Venkatesh A, Goossens N, Bain G, Lauwers GY, Koh AP, El-Abtah M, Ahmad NB, Hoshida H, Erstad DJ, Gunasekaran G, Lee Y, Yu ML, Chuang WL, Dai CY, Kobayashi M, Kumada H, Beppu T, Baba H, Mahajan M, Nair VD, Lanuti M, Villanueva A, Sangiovanni A, Iavarone M, Colombo M, Llovet JM, Subramanian A, Tager AM, Friedman SL, Baumert TF, Schwarz ME, Chung RT, Tanabe KK, Zhang B, Fuchs BC, Hoshida Y. Molecular Liver Cancer Prevention in Cirrhosis by Organ Transcriptome Analysis and Lysophosphatidic Acid Pathway Inhibition. Cancer Cell. 2016 Dec 12; 30(6):879-890. PMID: 27960085.
    View in: PubMed
  23. Shukha K, Mueller JL, Chung RT, Curry MP, Friedman DJ, Pollak MR, Berg AH. Most ApoL1 Is Secreted by the Liver. J Am Soc Nephrol. 2017 Apr; 28(4):1079-1083. PMID: 27932478.
    View in: PubMed
  24. Schaefer EA, Meixiong J, Mark C, Deik A, Motola DL, Fusco D, Yang A, Brisac C, Salloum S, Lin W, Clish CB, Peng LF, Chung RT. Apolipoprotein B100 is required for hepatitis C infectivity and Mipomersen inhibits hepatitis C. World J Gastroenterol. 2016 Dec 07; 22(45):9954-9965. PMID: 28018102.
    View in: PubMed
  25. Goto K, Kato N, Chung RT. Anti-hepatocellular carcinoma properties of the anti-alcoholism drug disulfiram discovered to enzymatically inhibit the AMPK-related kinase SNARK in vitro. Oncotarget. 2016 Nov 15; 7(46):74987-74999. PMID: 27602492.
    View in: PubMed
  26. Wang X, Zheng Z, Caviglia JM, Corey KE, Herfel TM, Cai B, Masia R, Chung RT, Lefkowitch JH, Schwabe RF, Tabas I. Hepatocyte TAZ/WWTR1 Promotes Inflammation and Fibrosis in Nonalcoholic Steatohepatitis. Cell Metab. 2016 Dec 13; 24(6):848-862. PMID: 28068223.
    View in: PubMed
  27. Sen DR, Kaminski J, Barnitz RA, Kurachi M, Gerdemann U, Yates KB, Tsao HW, Godec J, LaFleur MW, Brown FD, Tonnerre P, Chung RT, Tully DC, Allen TM, Frahm N, Lauer GM, Wherry EJ, Yosef N, Haining WN. The epigenetic landscape of T cell exhaustion. Science. 2016 12 02; 354(6316):1165-1169. PMID: 27789799.
    View in: PubMed
  28. Ma J, Hwang SJ, Pedley A, Massaro JM, Hoffmann U, Chung RT, Benjamin EJ, Levy D, Fox CS, Long MT. Bi-directional analysis between fatty liver and cardiovascular disease risk factors. J Hepatol. 2017 Feb; 66(2):390-397. PMID: 27729222.
    View in: PubMed
  29. Simon TG, Corey KE, Chung RT, Giugliano R. Cardiovascular Risk Reduction in Patients with Nonalcoholic Fatty Liver Disease: The Potential Role of Ezetimibe. Dig Dis Sci. 2016 Dec; 61(12):3425-3435. PMID: 27714510.
    View in: PubMed
  30. Salloum S, Holmes JA, Jindal R, Bale SS, Brisac C, Alatrakchi N, Lidofsky A, Kruger AJ, Fusco DN, Luther J, Schaefer EA, Lin W, Yarmush ML, Chung RT. Exposure to human immunodeficiency virus/hepatitis C virus in hepatic and stellate cell lines reveals cooperative profibrotic transcriptional activation between viruses and cell types. Hepatology. 2016 Dec; 64(6):1951-1968. PMID: 27531241.
    View in: PubMed
  31. Allegretti AS, Ortiz G, Kalim S, Wibecan J, Zhang D, Shan HY, Xu D, Chung RT, Karumanchi SA, Thadhani RI. Siglec-7 as a Novel Biomarker to Predict Mortality in Decompensated Cirrhosis and Acute Kidney Injury. Dig Dis Sci. 2016 Dec; 61(12):3609-3620. PMID: 27655105.
    View in: PubMed
  32. Rajbhandari R, Chung RT. Treatment of Hepatitis B: A Concise Review. Clin Transl Gastroenterol. 2016 Sep 15; 7(9):e190. PMID: 27628420.
    View in: PubMed
  33. Sise ME, Wisocky J, Rosales IA, Chute D, Holmes JA, Corapi KM, Babitt JL, Tangren JS, Hashemi N, Lundquist AL, Williams WW, Mount DB, Andersson KL, Rennke HG, Smith RN, Colvin R, Thadhani RI, Chung RT. Lupus-like Immune Complex-mediated Glomerulonephritis in Patients with Hepatitis C Virus Infection Treated with Oral, Interferon-free, Direct-acting Antiviral Therapy. Kidney Int Rep. 2016 Sep; 1(3):135-143. PMID: 27990496.
    View in: PubMed
  34. Jourdain G, Ngo-Giang-Huong N, Cressey TR, Hua L, Harrison L, Tierney C, Salvadori N, Decker L, Traisathit P, Sirirungsi W, Khamduang W, Bowonwatanuwong C, Puthanakit T, Siberry GK, Watts DH, Murphy TV, Achalapong J, Hongsiriwon S, Klinbuayaem V, Thongsawat S, Chung RT, Pol S, Chotivanich N. Prevention of mother-to-child transmission of hepatitis B virus: a phase III, placebo-controlled, double-blind, randomized clinical trial to assess the efficacy and safety of a short course of tenofovir disoproxil fumarate in women with hepatitis B virus e-antigen. BMC Infect Dis. 2016 Aug 09; 16:393. PMID: 27506549; PMCID: PMC4977630.
  35. Rajbhandari R, Simon RE, Chung RT, Ananthakrishnan AN. Racial Disparities in Inhospital Outcomes for Hepatocellular Carcinoma in the United States. Mayo Clin Proc. 2016 Sep; 91(9):1173-82. PMID: 27497857.
    View in: PubMed
  36. Gane EJ, Kowdley KV, Pound D, Stedman CA, Davis M, Etzkorn K, Gordon SC, Bernstein D, Everson G, Rodriguez-Torres M, Tsai N, Khalid O, Yang JC, Lu S, Dvory-Sobol H, Stamm LM, Brainard DM, McHutchison JG, Tong M, Chung RT, Beavers K, Poulos JE, Kwo PY, Nguyen MH. Efficacy of Sofosbuvir, Velpatasvir, and GS-9857 in Patients With Hepatitis C Virus Genotype 2, 3, 4, or 6 Infections in an Open-Label, Phase 2 Trial. Gastroenterology. 2016 Nov; 151(5):902-909. PMID: 27486033.
    View in: PubMed
  37. Lin MV, Sise ME, Pavlakis M, Amundsen BM, Chute D, Rutherford AE, Chung RT, Curry MP, Hanifi JM, Gabardi S, Chandraker A, Heher EC, Elias N, Riella LV. Efficacy and Safety of Direct Acting Antivirals in Kidney Transplant Recipients with Chronic Hepatitis C Virus Infection. PLoS One. 2016; 11(7):e0158431. PMID: 27415632; PMCID: PMC4945034.
  38. Brisac C, Salloum S, Yang V, Schaefer EA, Holmes JA, Chevaliez S, Hong J, Carlton-Smith C, Alatrakchi N, Kruger A, Lin W, Chung RT. IQGAP2 is a novel interferon-alpha antiviral effector gene acting non-conventionally through the NF-?B pathway. J Hepatol. 2016 Nov; 65(5):972-979. PMID: 27401546.
    View in: PubMed
  39. Chhatwal J, Wang X, Ayer T, Kabiri M, Chung RT, Hur C, Donohue JM, Roberts MS, Kanwal F. Hepatitis C Disease Burden in the United States in the era of oral direct-acting antivirals. Hepatology. 2016 Nov; 64(5):1442-1450. PMID: 27015107.
    View in: PubMed
  40. Felmlee DJ, Coilly A, Chung RT, Samuel D, Baumert TF. New perspectives for preventing hepatitis C virus liver graft infection. Lancet Infect Dis. 2016 Jun; 16(6):735-745. PMID: 27301929; PMCID: PMC4911897 [Available on 06/01/17].
  41. Chawla A, Bosco J, Lim TC, Gaikwad V, Chung R. Systemic-pulmonary artery shunt: A rare cause of false-positive filling defect in the pulmonary arteries. J Med Imaging Radiat Oncol. 2017 Feb; 61(1):82-84. PMID: 27162167.
    View in: PubMed
  42. Mukherjee P, Chawla A, Singh D, Chung R. The "gallbladder pearl necklace" sign. Abdom Radiol (NY). 2016 May; 41(5):1001-2. PMID: 27193797.
    View in: PubMed
  43. Reuben A, Tillman H, Fontana RJ, Davern T, McGuire B, Stravitz RT, Durkalski V, Larson AM, Liou I, Fix O, Schilsky M, McCashland T, Hay JE, Murray N, Shaikh OS, Ganger D, Zaman A, Han SB, Chung RT, Smith A, Brown R, Crippin J, Harrison ME, Koch D, Munoz S, Reddy KR, Rossaro L, Satyanarayana R, Hassanein T, Hanje AJ, Olson J, Subramanian R, Karvellas C, Hameed B, Sherker AH, Robuck P, Lee WM. Outcomes in Adults With Acute Liver Failure Between 1998 and 2013: An Observational Cohort Study. Ann Intern Med. 2016 Jun 07; 164(11):724-32. PMID: 27043883.
    View in: PubMed
  44. Guimaraes AR, Siqueira L, Uppal R, Alford J, Fuchs BC, Yamada S, Tanabe K, Chung RT, Lauwers G, Chew ML, Boland GW, Sahani DV, Vangel M, Hahn PF, Caravan P. T2 relaxation time is related to liver fibrosis severity. Quant Imaging Med Surg. 2016 Apr; 6(2):103-14. PMID: 27190762; PMCID: PMC4858462.
  45. Simon TG, Bonilla H, Yan P, Chung RT, Butt AA. Atorvastatin and fluvastatin are associated with dose-dependent reductions in cirrhosis and hepatocellular carcinoma, among patients with hepatitis C virus: Results from ERCHIVES. Hepatology. 2016 Jul; 64(1):47-57. PMID: 26891205; PMCID: PMC4917438 [Available on 07/01/17].
  46. Saxena V, Koraishy FM, Sise ME, Lim JK, Schmidt M, Chung RT, Liapakis A, Nelson DR, Fried MW, Terrault NA. Safety and efficacy of sofosbuvir-containing regimens in hepatitis C-infected patients with impaired renal function. Liver Int. 2016 Jun; 36(6):807-16. PMID: 26923436.
    View in: PubMed
  47. Butt AA, Yan P, Shaikh OS, Chung RT, Sherman KE. Treatment adherence and virological response rates in hepatitis C virus infected persons treated with sofosbuvir-based regimens: results from ERCHIVES. Liver Int. 2016 Sep; 36(9):1275-83. PMID: 26928927.
    View in: PubMed
  48. Holmes JA, Chung RT. Viral hepatitis: HCV compartmentalization in HCC: driver, passenger or both? Nat Rev Gastroenterol Hepatol. 2016 May; 13(5):254-6. PMID: 27006254.
    View in: PubMed
  49. Zhou C, York SR, Chen JY, Pondick JV, Motola DL, Chung RT, Mullen AC. Long noncoding RNAs expressed in human hepatic stellate cells form networks with extracellular matrix proteins. Genome Med. 2016 Mar 23; 8(1):31. PMID: 27007663; PMCID: PMC4804564.
  50. Patel SJ, Luther J, Bohr S, Iracheta-Vellve A, Li M, King KR, Chung RT, Yarmush ML. A Novel Resolvin-Based Strategy for Limiting Acetaminophen Hepatotoxicity. Clin Transl Gastroenterol. 2016 Mar 17; 7:e153. PMID: 26986653; PMCID: PMC4822092.
  51. Allegretti AS, Ortiz G, Cui J, Wenger J, Bhan I, Chung RT, Thadhani RI, Irani Z. Changes in Kidney Function After Transjugular Intrahepatic Portosystemic Shunts Versus Large-Volume Paracentesis in Cirrhosis: A Matched Cohort Analysis. Am J Kidney Dis. 2016 Sep; 68(3):381-91. PMID: 26994685; PMCID: PMC5002241 [Available on 09/01/17].
  52. Chusri P, Kumthip K, Hong J, Zhu C, Duan X, Jilg N, Fusco DN, Brisac C, Schaefer EA, Cai D, Peng LF, Maneekarn N, Lin W, Chung RT. HCV induces transforming growth factor ß1 through activation of endoplasmic reticulum stress and the unfolded protein response. Sci Rep. 2016 Mar 01; 6:22487. PMID: 26927933; PMCID: PMC4772380.
  53. Mueller JL, King LY, Johnson KB, Gao T, Nephew LD, Kothari D, Simpson MA, Zheng H, Wei L, Corey KE, Misdraji J, Lee JH, Lin MV, Gogela NA, Fuchs BC, Tanabe KK, Gordon FD, Curry MP, Chung RT. Impact of EGF, IL28B, and PNPLA3 polymorphisms on the outcome of allograft hepatitis C: a multicenter study. Clin Transplant. 2016 Apr; 30(4):452-60. PMID: 26854475; PMCID: PMC4868041.
  54. Corey KE, Kartoun U, Zheng H, Chung RT, Shaw SY. Using an Electronic Medical Records Database to Identify Non-Traditional Cardiovascular Risk Factors in Nonalcoholic Fatty Liver Disease. Am J Gastroenterol. 2016 May; 111(5):671-6. PMID: 26925881; PMCID: PMC4864030.
  55. DePeralta DK, Wei L, Ghoshal S, Schmidt B, Lauwers GY, Lanuti M, Chung RT, Tanabe KK, Fuchs BC. Metformin prevents hepatocellular carcinoma development by suppressing hepatic progenitor cell activation in a rat model of cirrhosis. Cancer. 2016 Apr 15; 122(8):1216-27. PMID: 26914713; PMCID: PMC4828262 [Available on 04/15/17].
  56. Corey KE, Klebanoff MJ, Tramontano AC, Chung RT, Hur C. Screening for Nonalcoholic Steatohepatitis in Individuals with Type 2 Diabetes: A Cost-Effectiveness Analysis. Dig Dis Sci. 2016 Jul; 61(7):2108-17. PMID: 26825843; PMCID: PMC4920690.
  57. Butt AA, Yan P, Shaikh OS, Chung RT, Sherman KE. Sofosbuvir-based regimens in clinical practice achieve SVR rates closer to clinical trials: results from ERCHIVES. Liver Int. 2016 May; 36(5):651-8. PMID: 26616353.
    View in: PubMed
  58. Bertero T, Cottrill KA, Annis S, Bhat B, Gochuico BR, Osorio JC, Rosas I, Haley KJ, Corey KE, Chung RT, Nelson Chau B, Chan SY. A YAP/TAZ-miR-130/301 molecular circuit exerts systems-level control of fibrosis in a network of human diseases and physiologic conditions. Sci Rep. 2015 Dec 15; 5:18277. PMID: 26667495; PMCID: PMC4678880.
  59. Sise ME, Bloom AK, Wisocky J, Lin MV, Gustafson JL, Lundquist AL, Steele D, Thiim M, Williams WW, Hashemi N, Kim AY, Thadhani R, Chung RT. Treatment of hepatitis C virus-associated mixed cryoglobulinemia with direct-acting antiviral agents. Hepatology. 2016 Feb; 63(2):408-17. PMID: 26474537; PMCID: PMC4718772 [Available on 02/01/17].
  60. Simon TG, Chung RT. Reply. Hepatology. 2016 Jun; 63(6):2066-7. PMID: 26316092.
    View in: PubMed
  61. Butt AA, Yan P, Simon TG, Chung RT, Abou-Samra AB. Changes in circulating lipids level over time after acquiring HCV infection: results from ERCHIVES. BMC Infect Dis. 2015 Nov 11; 15:510. PMID: 26558512; PMCID: PMC4642733.
  62. Chawla A, Shenoy J, Chokkappan K, Chung R. Imaging Features of Sinonasal Inverted Papilloma: A Pictorial Review. Curr Probl Diagn Radiol. 2016 Sep-Oct; 45(5):347-53. PMID: 26632214.
    View in: PubMed
  63. Everson GT, Towner WJ, Davis MN, Wyles DL, Nahass RG, Thuluvath PJ, Etzkorn K, Hinestrosa F, Tong M, Rabinovitz M, McNally J, Brainard DM, Han L, Doehle B, McHutchison JG, Morgan T, Chung RT, Tran TT. Sofosbuvir With Velpatasvir in Treatment-Naive Noncirrhotic Patients With Genotype 1 to 6 Hepatitis C Virus Infection: A Randomized Trial. Ann Intern Med. 2015 Dec 01; 163(11):818-26. PMID: 26551051.
    View in: PubMed
  64. Liang HC, Russell C, Mitra V, Chung R, Hye A, Bazenet C, Lovestone S, Pike I, Ward M. Glycosylation of Human Plasma Clusterin Yields a Novel Candidate Biomarker of Alzheimer's Disease. J Proteome Res. 2015 Dec 04; 14(12):5063-76. PMID: 26488311.
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  65. Wagschal A, Najafi-Shoushtari SH, Wang L, Goedeke L, Sinha S, deLemos AS, Black JC, Ramírez CM, Li Y, Tewhey R, Hatoum I, Shah N, Lu Y, Kristo F, Psychogios N, Vrbanac V, Lu YC, Hla T, de Cabo R, Tsang JS, Schadt E, Sabeti PC, Kathiresan S, Cohen DE, Whetstine J, Chung RT, Fernández-Hernando C, Kaplan LM, Bernards A, Gerszten RE, Näär AM. Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis. Nat Med. 2015 Nov; 21(11):1290-7. PMID: 26501192; PMCID: PMC4993048.
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  149. Ding Q, Lee YK, Schaefer EA, Peters DT, Veres A, Kim K, Kuperwasser N, Motola DL, Meissner TB, Hendriks WT, Trevisan M, Gupta RM, Moisan A, Banks E, Friesen M, Schinzel RT, Xia F, Tang A, Xia Y, Figueroa E, Wann A, Ahfeldt T, Daheron L, Zhang F, Rubin LL, Peng LF, Chung RT, Musunuru K, Cowan CA. A TALEN genome-editing system for generating human stem cell-based disease models. Cell Stem Cell. 2013 Feb 07; 12(2):238-51. PMID: 23246482; PMCID: PMC3570604.
  150. Shao RX, Zhang L, Hong Z, Goto K, Cheng D, Chen WC, Jilg N, Kumthip K, Fusco DN, Peng LF, Chung RT. SOCS1 abrogates IFN's antiviral effect on hepatitis C virus replication. Antiviral Res. 2013 Feb; 97(2):101-7. PMID: 23237992; PMCID: PMC3764487.
  151. Chen JY, Chung RT. Future classes of hepatitis C virus therapeutic agents. Infect Dis Clin North Am. 2012 Dec; 26(4):949-66. PMID: 23083826; PMCID: PMC4624290.
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  154. Huang YW, Chung RT. Management of hepatitis B reactivation in patients receiving cancer chemotherapy. Therap Adv Gastroenterol. 2012 Sep; 5(5):359-70. PMID: 22973419; PMCID: PMC3437537.
  155. Sahani DV, Agarwal S, Chung RT. The double-edged sword of functional liver imaging. Radiology. 2012 Sep; 264(3):621-3. PMID: 22919034.
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  156. Chung R. Magnetic resonance imaging of the axial structures of the brain. BMJ. 2012 Aug 10; 345:e5268. PMID: 22885398.
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  157. Chung R. Magnetic resonance imaging of sagittal structures in the knee. BMJ. 2012 Aug 09; 345:e5266. PMID: 22879635.
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  158. Chung R. Coronal oblique proton density weighted magnetic resonance imaging of the right shoulder. BMJ. 2012 Aug 09; 345:e5270. PMID: 22879636.
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  159. Rutherford A, King LY, Hynan LS, Vedvyas C, Lin W, Lee WM, Chung RT. Development of an accurate index for predicting outcomes of patients with acute liver failure. Gastroenterology. 2012 Nov; 143(5):1237-43. PMID: 22885329; PMCID: PMC3480539.
  160. Chung RT, Stravitz RT, Fontana RJ, Schiodt FV, Mehal WZ, Reddy KR, Lee WM. Pathogenesis of liver injury in acute liver failure. Gastroenterology. 2012 Sep; 143(3):e1-e7. PMID: 22796239; PMCID: PMC3641754.
  161. Delgado-Borrego A, Smith L, Jonas MM, Hall CA, Negre B, Jordan SH, Ogrodowicz M, Raza R, Ludwig DA, Miller T, Lipshultz SE, Gonzalez-Peralta R, Chung RT. Expected and actual case ascertainment and treatment rates for children infected with hepatitis C in Florida and the United States: epidemiologic evidence from statewide and nationwide surveys. J Pediatr. 2012 Nov; 161(5):915-21. PMID: 22765955.
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  163. Butt AA, Umbleja T, Andersen JW, Sherman KE, Chung RT. Impact of peginterferon alpha and ribavirin treatment on lipid profiles and insulin resistance in Hepatitis C virus/HIV-coinfected persons: the AIDS Clinical Trials Group A5178 Study. Clin Infect Dis. 2012 Sep; 55(5):631-8. PMID: 22563020; PMCID: PMC3491848.
  164. Schaefer EA, Chung RT. Anti-hepatitis C virus drugs in development. Gastroenterology. 2012 May; 142(6):1340-1350.e1. PMID: 22537441.
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  165. Rodgers MA, Villareal VA, Schaefer EA, Peng LF, Corey KE, Chung RT, Yang PL. Lipid metabolite profiling identifies desmosterol metabolism as a new antiviral target for hepatitis C virus. J Am Chem Soc. 2012 Apr 25; 134(16):6896-9. PMID: 22480142; PMCID: PMC3375380.
  166. Chung RT, Umbleja T, Chen JY, Andersen JW, Butt AA, Sherman KE. Extended therapy with pegylated interferon and weight-based ribavirin for HCV-HIV coinfected patients. HIV Clin Trials. 2012 Mar-Apr; 13(2):70-82. PMID: 22510354; PMCID: PMC3367320.
  167. Corey KE, Zheng H, Mendez-Navarro J, Delgado-Borrego A, Dienstag JL, Chung RT. Serum vitamin D levels are not predictive of the progression of chronic liver disease in hepatitis C patients with advanced fibrosis. PLoS One. 2012; 7(2):e27144. PMID: 22359532; PMCID: PMC3281016.
  168. Zhang L, Hong Z, Lin W, Shao RX, Goto K, Hsu VW, Chung RT. ARF1 and GBF1 generate a PI4P-enriched environment supportive of hepatitis C virus replication. PLoS One. 2012; 7(2):e32135. PMID: 22359663; PMCID: PMC3281116.
  169. Corey KE, Lai M, Gelrud LG, Misdraji J, Barlow LL, Zheng H, Andersson KL, Thiim M, Pratt DS, Chung RT. Non-high-density lipoprotein cholesterol as a biomarker for nonalcoholic steatohepatitis. Clin Gastroenterol Hepatol. 2012 Jun; 10(6):651-6. PMID: 22330232; PMCID: PMC3360815.
  170. John S, Chung RT. Early liver transplantation for severe alcoholic hepatitis. N Engl J Med. 2012 Feb 02; 366(5):478; author reply 479. PMID: 22296090.
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  171. Chung RT. A watershed moment in the treatment of hepatitis C. N Engl J Med. 2012 Jan 19; 366(3):273-5. PMID: 22256811.
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  172. Schulze Zur Wiesch J, Ciuffreda D, Lewis-Ximenez L, Kasprowicz V, Nolan BE, Streeck H, Aneja J, Reyor LL, Allen TM, Lohse AW, McGovern B, Chung RT, Kwok WW, Kim AY, Lauer GM. Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence. J Exp Med. 2012 Jan 16; 209(1):61-75. PMID: 22213804; PMCID: PMC3260872.
  173. Opravil M, Rodriguez-Torres M, Rockstroh J, Snoeck E, Chung RT, Tietz A, Torriani FJ. The dose-response relationship of peginterferon alfa-2a and ribavirin in the treatment of patients coinfected with HIV-HCV. HIV Clin Trials. 2012 Jan-Feb; 13(1):33-45. PMID: 22306586.
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  174. Schaefer EA, Chung RT. The impact of human gene polymorphisms on HCV infection and disease outcome. Semin Liver Dis. 2011 Nov; 31(4):375-86. PMID: 22189977.
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  175. Sherman KE, Thomas DL, Chung RT. Human immunodeficiency virus and liver disease forum 2010: conference proceedings. Hepatology. 2011 Dec; 54(6):2245-53. PMID: 21898501; PMCID: PMC3795389.
  176. Dayyeh BK, Gupta N, Sherman KE, de Bakker PI, Chung RT. IL28B alleles exert an additive dose effect when applied to HCV-HIV coinfected persons undergoing peginterferon and ribavirin therapy. PLoS One. 2011; 6(10):e25753. PMID: 22003405; PMCID: PMC3189209.
  177. Taylor RM, Tujios S, Jinjuvadia K, Davern T, Shaikh OS, Han S, Chung RT, Lee WM, Fontana RJ. Short and long-term outcomes in patients with acute liver failure due to ischemic hepatitis. Dig Dis Sci. 2012 Mar; 57(3):777-85. PMID: 21948394.
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  178. Fusco DN, Chung RT. Novel therapies for hepatitis C: insights from the structure of the virus. Annu Rev Med. 2012; 63:373-87. PMID: 21942423.
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  179. Zhao H, Lin W, Kumthip K, Cheng D, Fusco DN, Hofmann O, Jilg N, Tai AW, Goto K, Zhang L, Hide W, Jang JY, Peng LF, Chung RT. A functional genomic screen reveals novel host genes that mediate interferon-alpha's effects against hepatitis C virus. J Hepatol. 2012 Feb; 56(2):326-33. PMID: 21888876; PMCID: PMC3261326.
  180. Peng LF, Schaefer EA, Maloof N, Skaff A, Berical A, Belon CA, Heck JA, Lin W, Frick DN, Allen TM, Miziorko HM, Schreiber SL, Chung RT. Ceestatin, a novel small molecule inhibitor of hepatitis C virus replication, inhibits 3-hydroxy-3-methylglutaryl-coenzyme A synthase. J Infect Dis. 2011 Aug 15; 204(4):609-16. PMID: 21791663; PMCID: PMC3144167.
  181. Patwardhan V, Paul S, Corey KE, Mazhar SM, Richter JM, Thiim M, Chung RT. Hepatocellular carcinoma screening rates vary by etiology of cirrhosis and involvement of gastrointestinal sub-specialists. Dig Dis Sci. 2011 Nov; 56(11):3316-22. PMID: 21805170; PMCID: PMC3773181.
  182. Jilg N, Chung RT. Adding to the toolbox: receptor tyrosine kinases as potential targets in the treatment of hepatitis C. J Hepatol. 2012 Jan; 56(1):282-4. PMID: 21784050.
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  183. O'Brien TR, Everhart JE, Morgan TR, Lok AS, Chung RT, Shao Y, Shiffman ML, Dotrang M, Sninsky JJ, Bonkovsky HL, Pfeiffer RM. An IL28B genotype-based clinical prediction model for treatment of chronic hepatitis C. PLoS One. 2011; 6(7):e20904. PMID: 21760886; PMCID: PMC3132753.
  184. Jang JY, Chung RT. Chronic hepatitis C. Gut Liver. 2011 Jun; 5(2):117-32. PMID: 21814590; PMCID: PMC3140655.
  185. Abu Dayyeh BK, Yang M, Fuchs BC, Karl DL, Yamada S, Sninsky JJ, O'Brien TR, Dienstag JL, Tanabe KK, Chung RT. A functional polymorphism in the epidermal growth factor gene is associated with risk for hepatocellular carcinoma. Gastroenterology. 2011 Jul; 141(1):141-9. PMID: 21440548; PMCID: PMC3129453.
  186. Rogal SS, Landsittel D, Surman O, Chung RT, Rutherford A. Pretransplant depression, antidepressant use, and outcomes of orthotopic liver transplantation. Liver Transpl. 2011 Mar; 17(3):251-60. PMID: 21384507; PMCID: PMC3078692.
  187. Goldwasser J, Cohen PY, Lin W, Kitsberg D, Balaguer P, Polyak SJ, Chung RT, Yarmush ML, Nahmias Y. Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism. J Hepatol. 2011 Nov; 55(5):963-71. PMID: 21354229; PMCID: PMC3197749.
  188. Chen JY, Chung RT. Can we use the "C" word with confidence? Cure for chronic hepatitis C. Gastroenterology. 2011 Mar; 140(3):766-8. PMID: 21256845.
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  189. Fusco DN, Chung RT. New protease inhibitors for HCV--help is on the way. J Hepatol. 2011 Jun; 54(6):1087-9. PMID: 21232563.
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  190. Sherman KE, Andersen JW, Butt AA, Umbleja T, Alston B, Koziel MJ, Peters MG, Sulkowski M, Goodman ZD, Chung RT. Sustained long-term antiviral maintenance therapy in HCV/HIV-coinfected patients (SLAM-C). J Acquir Immune Defic Syndr. 2010 Dec 15; 55(5):597-605. PMID: 20921898; PMCID: PMC3017670.
  191. Zhang L, Jilg N, Shao RX, Lin W, Fusco DN, Zhao H, Goto K, Peng LF, Chen WC, Chung RT. IL28B inhibits hepatitis C virus replication through the JAK-STAT pathway. J Hepatol. 2011 Aug; 55(2):289-98. PMID: 21147189; PMCID: PMC3068235.
  192. Abu Dayyeh BK, Yang M, Dienstag JL, Chung RT. The effects of angiotensin blocking agents on the progression of liver fibrosis in the HALT-C Trial cohort. Dig Dis Sci. 2011 Feb; 56(2):564-8. PMID: 21136163; PMCID: PMC3142358.
  193. Lin W, Wu G, Li S, Weinberg EM, Kumthip K, Peng LF, Méndez-Navarro J, Chen WC, Jilg N, Zhao H, Goto K, Zhang L, Brockman MA, Schuppan D, Chung RT. HIV and HCV cooperatively promote hepatic fibrogenesis via induction of reactive oxygen species and NFkappaB. J Biol Chem. 2011 Jan 28; 286(4):2665-74. PMID: 21098019; PMCID: PMC3024762.
  194. Han SH, Reddy KR, Keeffe EB, Soldevila-Pico C, Gish R, Chung RT, Degertekin B, Lok A. Clinical outcomes of liver transplantation for HBV-related hepatocellular carcinoma: data from the NIH HBV OLT study. Clin Transplant. 2011 Mar-Apr; 25(2):E152-62. PMID: 21077950; PMCID: PMC3771871.
  195. Chung RT, Poordad FF, Hassanein T, Zhou X, Lentz E, Prabhakar A, Di Bisceglie AM. Association of host pharmacodynamic effects with virologic response to pegylated interferon alfa-2a/ribavirin in chronic hepatitis C. Hepatology. 2010 Dec; 52(6):1906-14. PMID: 21064034; PMCID: PMC3731377.
  196. Jang JY, Shao RX, Lin W, Weinberg E, Chung WJ, Tsai WL, Zhao H, Goto K, Zhang L, Mendez-Navarro J, Jilg N, Peng LF, Brockman MA, Chung RT. HIV infection increases HCV-induced hepatocyte apoptosis. J Hepatol. 2011 Apr; 54(4):612-20. PMID: 21146890; PMCID: PMC3060969.
  197. Kim AY, Kuntzen T, Timm J, Nolan BE, Baca MA, Reyor LL, Berical AC, Feller AJ, Johnson KL, Schulze zur Wiesch J, Robbins GK, Chung RT, Walker BD, Carrington M, Allen TM, Lauer GM. Spontaneous control of HCV is associated with expression of HLA-B 57 and preservation of targeted epitopes. Gastroenterology. 2011 Feb; 140(2):686-696.e1. PMID: 20875418; PMCID: PMC3021586.
  198. Moriguchi H, Chung RT, Mihara M, Sato C. Generation of human induced pluripotent stem cells from liver progenitor cells by only small molecules. Hepatology. 2010 Sep; 52(3):1169; author reply 1169-70. PMID: 20812362.
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  199. Jang JY, Chung RT. New treatments for chronic hepatitis C. Korean J Hepatol. 2010 Sep; 16(3):263-77. PMID: 20924208; PMCID: PMC3304602.
  200. Méndez-Navarro J, Corey KE, Zheng H, Barlow LL, Jang JY, Lin W, Zhao H, Shao RX, McAfee SL, Chung RT. Hepatitis B screening, prophylaxis and re-activation in the era of rituximab-based chemotherapy. Liver Int. 2011 Mar; 31(3):330-9. PMID: 20738779; PMCID: PMC3736143.
  201. Delgado-Borrego A, Healey D, Negre B, Christofi M, Sabharwal S, Ludwig DA, Chung RT, Jonas MM. Influence of body mass index on outcome of pediatric chronic hepatitis C virus infection. J Pediatr Gastroenterol Nutr. 2010 Aug; 51(2):191-7. PMID: 20531022; PMCID: PMC2910782.
  202. King LY, Chung RT. When treating cancer, please don't forget hepatitis B. Oncologist. 2010; 15(8):826-9. PMID: 20647389; PMCID: PMC3228019.
  203. Shao RX, Zhang L, Peng LF, Sun E, Chung WJ, Jang JY, Tsai WL, Hyppolite G, Chung RT. Suppressor of cytokine signaling 3 suppresses hepatitis C virus replication in an mTOR-dependent manner. J Virol. 2010 Jun; 84(12):6060-9. PMID: 20375166; PMCID: PMC2876663.
  204. Chung RT. Reaping the early harvest of the genomics revolution. Gastroenterology. 2010 May; 138(5):1653-4. PMID: 20332044.
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  205. Tsai WL, Chung RT. Viral hepatocarcinogenesis. Oncogene. 2010 Apr 22; 29(16):2309-24. PMID: 20228847; PMCID: PMC3148694.
  206. Lin W, Tsai WL, Shao RX, Wu G, Peng LF, Barlow LL, Chung WJ, Zhang L, Zhao H, Jang JY, Chung RT. Hepatitis C virus regulates transforming growth factor beta1 production through the generation of reactive oxygen species in a nuclear factor kappaB-dependent manner. Gastroenterology. 2010 Jun; 138(7):2509-18, 2518.e1. PMID: 20230822; PMCID: PMC2883661.
  207. Sherman KE, Soriano V, Chung RT. Human immunodeficiency virus and liver disease: conference proceedings. Hepatology. 2010 Mar; 51(3):1046-54. PMID: 20041404.
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  208. Moriguchi H, Chung RT, Sato C. An indicator for evaluating the risk of cancerous transformations of human induced pluripotent stem cells. Hepatology. 2010 Mar; 51(3):1085-6. PMID: 19957369.
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  209. Moriguchi H, Chung RT, Sato C. Tumorigenicity of human induced pluripotent stem cells depends on the balance of gene expression between p21 and p53. Hepatology. 2010 Mar; 51(3):1088-9. PMID: 19957368.
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  210. Sherman KE, Rouster SD, Stanford S, Blackard JT, Shire N, Koziel M, Peters M, Chung RT. Hepatitis C virus (HCV) quasispecies complexity and selection in HCV/HIV-coinfected subjects treated with interferon-based regimens. J Infect Dis. 2010 Mar; 201(5):712-9. PMID: 20105080; PMCID: PMC2827649.
  211. Moriguchi H, Chung RT, Sato C. An identification of novel therapy for human hepatocellular carcinoma by using human induced pluripotent stem cells. Hepatology. 2010 Mar; 51(3):1090-1. PMID: 20041407.
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  212. Delgado-Borrego A, Jordan SH, Negre B, Healey D, Lin W, Kamegaya Y, Christofi M, Ludwig DA, Lok AS, Chung RT. Reduction of insulin resistance with effective clearance of hepatitis C infection: results from the HALT-C trial. Clin Gastroenterol Hepatol. 2010 May; 8(5):458-62. PMID: 20156586; PMCID: PMC2856733.
  213. Monto A, Schooley RT, Lai JC, Sulkowski MS, Chung RT, Pawlotsky JM, McHutchison JG, Jacobson IM. Lessons from HIV therapy applied to viral hepatitis therapy: summary of a workshop. Am J Gastroenterol. 2010 May; 105(5):989-1004; quiz 988, 1005. PMID: 20087331.
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  214. Contreras AM, Ochoa-Jiménez RJ, Celis A, Méndez C, Olivares L, Rebolledo CE, Hernandez-Lugo I, Aguirre-Zavala AI, Jiménez-Méndez R, Chung RT. High antibody level: an accurate serologic marker of viremia in asymptomatic people with hepatitis C infection. Transfusion. 2010 Jun; 50(6):1335-43. PMID: 20088833.
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  215. Moriguchi H, Chung RT, Sato C. New translational research on novel drugs for hepatitis C virus 1b infection by using a replicon system and human induced pluripotent stem cells. Hepatology. 2010 Jan; 51(1):344-5; author reply 345. PMID: 19957377.
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  216. Moriguchi H, Chung RT, Sato C. An identification of the novel combination therapy for hepatitis C virus 1b infection by using a replicon system and human induced pluripotent stem cells. Hepatology. 2010 Jan; 51(1):351-2. PMID: 20034040.
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  217. Schwarze-Zander C, Neibecker M, Othman S, Tural C, Clotet B, Blackard JT, Kupfer B, Luechters G, Chung RT, Rockstroh JK, Spengler U. GB virus C coinfection in advanced HIV type-1 disease is associated with low CCR5 and CXCR4 surface expression on CD4(+) T-cells. Antivir Ther. 2010; 15(5):745-52. PMID: 20710056; PMCID: PMC3210471.
  218. Méndez-Navarro J, Chirino RA, Corey KE, Gorospe EC, Zheng H, Morán S, Juarez JA, Chung RT, Dehesa-Violante M. A randomized controlled trial of double versus triple therapy with amantadine for genotype 1 chronic hepatitis C in Latino patients. Dig Dis Sci. 2010 Sep; 55(9):2629-35. PMID: 19960257; PMCID: PMC3747563.
  219. Schiødt FV, Chung RT, Schilsky ML, Hay JE, Christensen E, Lee WM. Outcome of acute liver failure in the elderly. Liver Transpl. 2009 Nov; 15(11):1481-7. PMID: 19877205; PMCID: PMC3123453.
  220. Corey KE, Servoss JC, Casson DR, Kim AY, Robbins GK, Franzini J, Twitchell K, Loomis SC, Abraczinskas DR, Terella AM, Dienstag JL, Chung RT. Pilot study of postexposure prophylaxis for hepatitis C virus in healthcare workers. Infect Control Hosp Epidemiol. 2009 Oct; 30(10):1000-5. PMID: 19743901; PMCID: PMC4331129.
  221. Corey KE, Kane E, Munroe C, Barlow LL, Zheng H, Chung RT. Hepatitis C virus infection and its clearance alter circulating lipids: implications for long-term follow-up. Hepatology. 2009 Oct; 50(4):1030-7. PMID: 19787818; PMCID: PMC4330996.
  222. McGovern BH, Birch CE, Bowen MJ, Reyor LL, Nagami EH, Chung RT, Kim AY. Improving the diagnosis of acute hepatitis C virus infection with expanded viral load criteria. Clin Infect Dis. 2009 Oct 01; 49(7):1051-60. PMID: 19725787; PMCID: PMC2741541.
  223. McGovern BH, Nagami EH, Birch CE, Bowen MJ, Reyor LL, Chung RT, Kim AY. Rate of sustained virologic response in relation to baseline hepatitis C virus (HCV) RNA level and rapid virologic clearance in persons with acute HCV infection. J Infect Dis. 2009 Sep 15; 200(6):877-81. PMID: 19673649; PMCID: PMC2762747.
  224. Corey KE, Mendez-Navarro J, Gorospe EC, Zheng H, Chung RT. Early treatment improves outcomes in acute hepatitis C virus infection: a meta-analysis. J Viral Hepat. 2010 Mar; 17(3):201-7. PMID: 19674285; PMCID: PMC3769693.
  225. Rodriguez-Torres M, Sulkowski MS, Chung RT, Hamzeh FM, Jensen DM. Factors associated with rapid and early virologic response to peginterferon alfa-2a/ribavirin treatment in HCV genotype 1 patients representative of the general chronic hepatitis C population. J Viral Hepat. 2010 Feb 01; 17(2):139-47. PMID: 19674282; PMCID: PMC2810441.
  226. Deshpande V, Sainani NI, Chung RT, Pratt DS, Mentha G, Rubbia-Brandt L, Lauwers GY. IgG4-associated cholangitis: a comparative histological and immunophenotypic study with primary sclerosing cholangitis on liver biopsy material. Mod Pathol. 2009 Oct; 22(10):1287-95. PMID: 19633647.
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  227. Zúñiga J, Romero V, Azocar J, Terreros D, Vargas-Rojas MI, Torres-García D, Jiménez-Alvarez L, Vargas-Alarcón G, Granados-Montiel J, Husain Z, Chung RT, Alper CA, Yunis EJ. Protective KIR-HLA interactions for HCV infection in intravenous drug users. Mol Immunol. 2009 Aug; 46(13):2723-7. PMID: 19552960; PMCID: PMC2813779.
  228. Kim AY, Chung RT. Coinfection with HIV-1 and HCV--a one-two punch. Gastroenterology. 2009 Sep; 137(3):795-814. PMID: 19549523; PMCID: PMC3146750.
  229. Lok AS, Everhart JE, Chung RT, Kim HY, Everson GT, Hoefs JC, Greenson JK, Sterling RK, Lindsay KL, Lee WM, Di Bisceglie AM, Bonkovsky HL, Ghany MG, Morishima C. Evolution of hepatic steatosis in patients with advanced hepatitis C: results from the hepatitis C antiviral long-term treatment against cirrhosis (HALT-C) trial. Hepatology. 2009 Jun; 49(6):1828-37. PMID: 19291787; PMCID: PMC2692566.
  230. Nelson AL, Millington TM, Sahani D, Chung RT, Bauer C, Hertl M, Warshaw AL, Conrad C. Hepatic portal venous gas: the ABCs of management. Arch Surg. 2009 Jun; 144(6):575-81; discussion 581. PMID: 19528392.
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  231. Welzel TM, Morgan TR, Bonkovsky HL, Naishadham D, Pfeiffer RM, Wright EC, Hutchinson AA, Crenshaw AT, Bashirova A, Carrington M, Dotrang M, Sterling RK, Lindsay KL, Fontana RJ, Lee WM, Di Bisceglie AM, Ghany MG, Gretch DR, Chanock SJ, Chung RT, O'Brien TR. Variants in interferon-alpha pathway genes and response to pegylated interferon-Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long-term treatment against cirrhosis trial. Hepatology. 2009 Jun; 49(6):1847-58. PMID: 19434718; PMCID: PMC2692559.
  232. Everhart JE, Lok AS, Kim HY, Morgan TR, Lindsay KL, Chung RT, Bonkovsky HL, Ghany MG. Weight-related effects on disease progression in the hepatitis C antiviral long-term treatment against cirrhosis trial. Gastroenterology. 2009 Aug; 137(2):549-57. PMID: 19445938; PMCID: PMC3148692.
  233. Zhao HT, Endo S, Ishikura S, Chung R, Hogg PJ, Hara A, El-Kabbani O. Structure/function analysis of a critical disulfide bond in the active site of L-xylulose reductase. Cell Mol Life Sci. 2009 May; 66(9):1570-9. PMID: 19337691.
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  234. Andersson KL, Chung RT. Monitoring during and after antiviral therapy for hepatitis B. Hepatology. 2009 May; 49(5 Suppl):S166-73. PMID: 19399793; PMCID: PMC2679854.
  235. Tai AW, Chung RT. Racial differences in response to interferon-based antiviral therapy for hepatitis C virus infection: a hardwiring issue? J Infect Dis. 2009 Apr 15; 199(8):1101-3. PMID: 19284288.
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  236. Tai AW, Benita Y, Peng LF, Kim SS, Sakamoto N, Xavier RJ, Chung RT. A functional genomic screen identifies cellular cofactors of hepatitis C virus replication. Cell Host Microbe. 2009 Mar 19; 5(3):298-307. PMID: 19286138; PMCID: PMC2756022.
  237. Kim KA, Lin W, Tai AW, Shao RX, Weinberg E, De Sa Borges CB, Bhan AK, Zheng H, Kamegaya Y, Chung RT. Hepatic SOCS3 expression is strongly associated with non-response to therapy and race in HCV and HCV/HIV infection. J Hepatol. 2009 Apr; 50(4):705-11. PMID: 19231005; PMCID: PMC3146466.
  238. Corey KE, Shah N, Misdraji J, Abu Dayyeh BK, Zheng H, Bhan AK, Chung RT. The effect of angiotensin-blocking agents on liver fibrosis in patients with hepatitis C. Liver Int. 2009 May; 29(5):748-53. PMID: 19220742; PMCID: PMC3151254.
  239. Shire NJ, Rao MB, Succop P, Buncher CR, Andersen JA, Butt AA, Chung RT, Sherman KE. Improving noninvasive methods of assessing liver fibrosis in patients with hepatitis C virus/human immunodeficiency virus co-infection. Clin Gastroenterol Hepatol. 2009 Apr; 7(4):471-80, 480.e1-2. PMID: 19268724; PMCID: PMC3159915.
  240. Tai AW, Chung RT. Treatment failure in hepatitis C: mechanisms of non-response. J Hepatol. 2009 Feb; 50(2):412-20. PMID: 19070928; PMCID: PMC2743341.
  241. Kuntzen T, Timm J, Berical A, Lennon N, Berlin AM, Young SK, Lee B, Heckerman D, Carlson J, Reyor LL, Kleyman M, McMahon CM, Birch C, Schulze Zur Wiesch J, Ledlie T, Koehrsen M, Kodira C, Roberts AD, Lauer GM, Rosen HR, Bihl F, Cerny A, Spengler U, Liu Z, Kim AY, Xing Y, Schneidewind A, Madey MA, Fleckenstein JF, Park VM, Galagan JE, Nusbaum C, Walker BD, Lake-Bakaar GV, Daar ES, Jacobson IM, Gomperts ED, Edlin BR, Donfield SM, Chung RT, Talal AH, Marion T, Birren BW, Henn MR, Allen TM. Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients. Hepatology. 2008 Dec; 48(6):1769-78. PMID: 19026009; PMCID: PMC2645896.
  242. McGovern BH, Abu Dayyeh BK, Chung RT. Avoiding therapeutic pitfalls: the rational use of specifically targeted agents against hepatitis C infection. Hepatology. 2008 Nov; 48(5):1700-12. PMID: 18972443.
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  244. Miller JC, Hahn PF, Chung RT, Thrall JH, Lee SI. Screening for hepatocellular carcinoma in cirrhotic patients. J Am Coll Radiol. 2008 Sep; 5(9):1012-4. PMID: 18755444.
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  245. Andersson KL, Salomon JA, Goldie SJ, Chung RT. Cost effectiveness of alternative surveillance strategies for hepatocellular carcinoma in patients with cirrhosis. Clin Gastroenterol Hepatol. 2008 Dec; 6(12):1418-24. PMID: 18848905; PMCID: PMC4340842.
  246. Martin NM, Abu Dayyeh BK, Chung RT. Anabolic steroid abuse causing recurrent hepatic adenomas and hemorrhage. World J Gastroenterol. 2008 Jul 28; 14(28):4573-5. PMID: 18680242; PMCID: PMC2731289.
  247. Hiasa Y, Kuzuhara H, Tokumoto Y, Konishi I, Yamashita N, Matsuura B, Michitaka K, Chung RT, Onji M. Hepatitis C virus replication is inhibited by 22beta-methoxyolean-12-ene-3beta, 24(4beta)-diol (ME3738) through enhancing interferon-beta. Hepatology. 2008 Jul; 48(1):59-69. PMID: 18459156.
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  248. Morgan TR, Lambrecht RW, Bonkovsky HL, Chung RT, Naishadham D, Sterling RK, Fontana RJ, Lee WM, Ghany MG, Wright EC, O'Brien TR. DNA polymorphisms and response to treatment in patients with chronic hepatitis C: results from the HALT-C trial. J Hepatol. 2008 Oct; 49(4):548-56. PMID: 18619701; PMCID: PMC3903339.
  249. Abu Dayyeh BK, Chung RT. Broadly neutralizing antibodies against hepatitis C virus: new hope for immunization? Gastroenterology. 2008 Jun; 134(7):2184-6. PMID: 18482587.
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  250. Rutherford A, Chung RT. Acute liver failure: mechanisms of hepatocyte injury and regeneration. Semin Liver Dis. 2008 May; 28(2):167-74. PMID: 18452116.
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  251. Nahmias Y, Goldwasser J, Casali M, van Poll D, Wakita T, Chung RT, Yarmush ML. Apolipoprotein B-dependent hepatitis C virus secretion is inhibited by the grapefruit flavonoid naringenin. Hepatology. 2008 May; 47(5):1437-45. PMID: 18393287; PMCID: PMC4500072.
  252. Swan T, Chung RT. Development of novel agents for the treatment of hepatitis C virus. Hepatology. 2008 Apr; 47(4):1426. PMID: 18322936.
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  253. Xia Y, Babitt JL, Sidis Y, Chung RT, Lin HY. Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin. Blood. 2008 May 15; 111(10):5195-204. PMID: 18326817; PMCID: PMC2384142.
  254. Romero V, Azocar J, Zúñiga J, Clavijo OP, Terreros D, Gu X, Husain Z, Chung RT, Amos C, Yunis EJ. Interaction of NK inhibitory receptor genes with HLA-C and MHC class II alleles in Hepatitis C virus infection outcome. Mol Immunol. 2008 May; 45(9):2429-36. PMID: 18289678; PMCID: PMC2387047.
  255. Delgado-Borrego A, Liu YS, Jordan SH, Agrawal S, Zhang H, Christofi M, Casson D, Cosimi AB, Chung RT. Prospective study of liver transplant recipients with HCV infection: evidence for a causal relationship between HCV and insulin resistance. Liver Transpl. 2008 Feb; 14(2):193-201. PMID: 18236394; PMCID: PMC4301430.
  256. Lin W, Weinberg EM, Tai AW, Peng LF, Brockman MA, Kim KA, Kim SS, Borges CB, Shao RX, Chung RT. HIV increases HCV replication in a TGF-beta1-dependent manner. Gastroenterology. 2008 Mar; 134(3):803-11. PMID: 18325393.
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  257. Tanabe KK, Lemoine A, Finkelstein DM, Kawasaki H, Fujii T, Chung RT, Lauwers GY, Kulu Y, Muzikansky A, Kuruppu D, Lanuti M, Goodwin JM, Azoulay D, Fuchs BC. Epidermal growth factor gene functional polymorphism and the risk of hepatocellular carcinoma in patients with cirrhosis. JAMA. 2008 Jan 02; 299(1):53-60. PMID: 18167406.
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  258. O'Leary JG, Zachary K, Misdraji J, Chung RT. De novo autoimmune hepatitis during immune reconstitution in an HIV-infected patient receiving highly active antiretroviral therapy. Clin Infect Dis. 2008 Jan 01; 46(1):e12-4. PMID: 18171203.
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  259. Chung RT, Gale M, Polyak SJ, Lemon SM, Liang TJ, Hoofnagle JH. Mechanisms of action of interferon and ribavirin in chronic hepatitis C: Summary of a workshop. Hepatology. 2008 Jan; 47(1):306-20. PMID: 18161743; PMCID: PMC2799164.
  260. Kasprowicz V, Schulze Zur Wiesch J, Kuntzen T, Nolan BE, Longworth S, Berical A, Blum J, McMahon C, Reyor LL, Elias N, Kwok WW, McGovern BG, Freeman G, Chung RT, Klenerman P, Lewis-Ximenez L, Walker BD, Allen TM, Kim AY, Lauer GM. High level of PD-1 expression on hepatitis C virus (HCV)-specific CD8+ and CD4+ T cells during acute HCV infection, irrespective of clinical outcome. J Virol. 2008 Mar; 82(6):3154-60. PMID: 18160439; PMCID: PMC2258997.
  261. Andersson KL, Chung RT. Hepatic schistosomiasis. Curr Treat Options Gastroenterol. 2007 Dec; 10(6):504-12. PMID: 18221611.
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  262. Corey KE, Chung RT. Treating difficult-to-treat hepatitis C virus infection: we may still need to push the ribavirin envelope. Gastroenterology. 2007 Dec; 133(6):2062-3. PMID: 18054581.
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  263. Kim AY, Chung RT. Sex, drugs, and hepatitis C virus in men who have sex with men: evidence for permucosal transmission. Gastroenterology. 2007 Nov; 133(5):1734-6; discussion 1736-7. PMID: 17983821.
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  264. Kang M, Chung RT. The role of early viral decline in the treatment of hepatitis C in HIV-1-coinfected persons. J Acquir Immune Defic Syndr. 2007 Nov 01; 46(3):371-3. PMID: 18090301.
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  265. Rutherford AE, Hynan LS, Borges CB, Forcione DG, Blackard JT, Lin W, Gorman AR, Shaikh OS, Reuben A, Harrison E, Reddy KR, Le WM, Chung RT. Serum apoptosis markers in acute liver failure: a pilot study. Clin Gastroenterol Hepatol. 2007 Dec; 5(12):1477-83. PMID: 17967565.
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  266. Tai AW, Chung RT. The hepatitis C virus plot thickens: enter claudin-1. Gastroenterology. 2007 Sep; 133(3):1041-2. PMID: 17854608.
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  267. Kuntzen T, Timm J, Berical A, Lewis-Ximenez LL, Jones A, Nolan B, Schulze zur Wiesch J, Li B, Schneidewind A, Kim AY, Chung RT, Lauer GM, Allen TM. Viral sequence evolution in acute hepatitis C virus infection. J Virol. 2007 Nov; 81(21):11658-68. PMID: 17699568; PMCID: PMC2168804.
  268. Peng LF, Kim SS, Matchacheep S, Lei X, Su S, Lin W, Runguphan W, Choe WH, Sakamoto N, Ikeda M, Kato N, Beeler AB, Porco JA, Schreiber SL, Chung RT. Identification of novel epoxide inhibitors of hepatitis C virus replication using a high-throughput screen. Antimicrob Agents Chemother. 2007 Oct; 51(10):3756-9. PMID: 17682098; PMCID: PMC2043288.
  269. Tokumoto Y, Hiasa Y, Horiike N, Michitaka K, Matsuura B, Chung RT, Onji M. Hepatitis C virus expression and interferon antiviral action is dependent on PKR expression. J Med Virol. 2007 Aug; 79(8):1120-7. PMID: 17596833.
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  270. Timm J, Li B, Daniels MG, Bhattacharya T, Reyor LL, Allgaier R, Kuntzen T, Fischer W, Nolan BE, Duncan J, Schulze zur Wiesch J, Kim AY, Frahm N, Brander C, Chung RT, Lauer GM, Korber BT, Allen TM. Human leukocyte antigen-associated sequence polymorphisms in hepatitis C virus reveal reproducible immune responses and constraints on viral evolution. Hepatology. 2007 Aug; 46(2):339-49. PMID: 17559151.
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  271. Tai AW, Chung RT. p53 restoration leads to tumor senescence and regression: implications for cancer therapy. Gastroenterology. 2007 Aug; 133(2):722-3. PMID: 17681193.
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  272. Aweeka FT, Kang M, Yu JY, Lizak P, Alston B, Chung RT. Pharmacokinetic evaluation of the effects of ribavirin on zidovudine triphosphate formation: ACTG 5092s Study Team. HIV Med. 2007 Jul; 8(5):288-94. PMID: 17561874.
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  273. Pekow JR, Bhan AK, Zheng H, Chung RT. Hepatic steatosis is associated with increased frequency of hepatocellular carcinoma in patients with hepatitis C-related cirrhosis. Cancer. 2007 Jun 15; 109(12):2490-6. PMID: 17487861.
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  274. Blackard JT, Hiasa Y, Smeaton L, Jamieson DJ, Rodriguez I, Mayer KH, Chung RT. Compartmentalization of hepatitis C virus (HCV) during HCV/HIV coinfection. J Infect Dis. 2007 Jun 15; 195(12):1765-73. PMID: 17492592; PMCID: PMC3210030.
  275. Schulze Zur Wiesch J, Lauer GM, Timm J, Kuntzen T, Neukamm M, Berical A, Jones AM, Nolan BE, Longworth SA, Kasprowicz V, McMahon C, Wurcel A, Lohse AW, Lewis-Ximenez LL, Chung RT, Kim AY, Allen TM, Walker BD. Immunologic evidence for lack of heterologous protection following resolution of HCV in patients with non-genotype 1 infection. Blood. 2007 Sep 01; 110(5):1559-69. PMID: 17475911; PMCID: PMC1975840.
  276. Timm J, Neukamm M, Kuntzen T, Kim AY, Chung RT, Brander C, Lauer GM, Walker BD, Allen TM. Characterization of full-length hepatitis C virus genotype 4 sequences. J Viral Hepat. 2007 May; 14(5):330-7. PMID: 17439522.
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  277. Behler CM, Vittinghoff E, Lin F, Chung RT, Peters MG, Robbins GK, Volberding PA. Hematologic toxicity associated with interferon-based hepatitis C therapy in HIV type 1-coinfected subjects. Clin Infect Dis. 2007 May 15; 44(10):1375-83. PMID: 17443478; PMCID: PMC4075655.
  278. Lauer GM, Chung RT. Vaccine-induced T-cell responses against HCV: one step taken, more to follow. Gastroenterology. 2007 Apr; 132(4):1626-8. PMID: 17418169.
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  279. O'Leary JG, Chan JL, McMahon CM, Chung RT. Atorvastatin does not exhibit antiviral activity against HCV at conventional doses: a pilot clinical trial. Hepatology. 2007 Apr; 45(4):895-8. PMID: 17393518.
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  280. Blackard JT, Kang M, St Clair JB, Lin W, Kamegaya Y, Sherman KE, Koziel MJ, Peters MG, Andersen J, Chung RT. Viral factors associated with cytokine expression during HCV/HIV co-infection. J Interferon Cytokine Res. 2007 Apr; 27(4):263-9. PMID: 17477814; PMCID: PMC4066618.
  281. Billington J, Hickling TP, Munro GH, Halai C, Chung R, Dodson GG, Daniels RS. Stability of a receptor-binding active human immunodeficiency virus type 1 recombinant gp140 trimer conferred by intermonomer disulfide bonding of the V3 loop: differential effects of protein disulfide isomerase on CD4 and coreceptor binding. J Virol. 2007 May; 81(9):4604-14. PMID: 17301129; PMCID: PMC1900172.
  282. Yachimski P, Shah N, Chung RT. Porphyria cutanea tarda. Clin Gastroenterol Hepatol. 2007 Feb; 5(2):e6. PMID: 17296523.
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  283. Lok AS, Everhart JE, Chung RT, Padmanabhan L, Greenson JK, Shiffman ML, Everson GT, Lindsay KL, Bonkovsky HL, Di Bisceglie AM, Lee WM, Morgan TR, Ghany MG, Morishima C. Hepatic steatosis in hepatitis C: comparison of diabetic and nondiabetic patients in the hepatitis C antiviral long-term treatment against cirrhosis trial. Clin Gastroenterol Hepatol. 2007 Feb; 5(2):245-54. PMID: 17296533.
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  284. Kim AY, Schulze zur Wiesch J, Kuntzen T, Timm J, Kaufmann DE, Duncan JE, Jones AM, Wurcel AG, Davis BT, Gandhi RT, Robbins GK, Allen TM, Chung RT, Lauer GM, Walker BD. Impaired hepatitis C virus-specific T cell responses and recurrent hepatitis C virus in HIV coinfection. PLoS Med. 2006 Dec; 3(12):e492. PMID: 17194190; PMCID: PMC1705826.
  285. Andrade-Sierra J, Contreras AM, Monteon FJ, Celis A, Gutierrez R, Montañez JL, Ruelas S, Baid-Agrawal S, Chung RT. Risk factors and incidence of posttransplant diabetes mellitus in Mexican kidney recipients. Arch Med Res. 2006 Nov; 37(8):961-6. PMID: 17045111.
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  286. Servoss JC, Kitch DW, Andersen JW, Reisler RB, Chung RT, Robbins GK. Predictors of antiretroviral-related hepatotoxicity in the adult AIDS Clinical Trial Group (1989-1999). J Acquir Immune Defic Syndr. 2006 Nov 01; 43(3):320-3. PMID: 16967041.
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  287. Blackard JT, Kang M, Sherman KE, Koziel MJ, Peters MG, Chung RT. Effects of HCV treatment on cytokine expression during HCV/HIV coinfection. J Interferon Cytokine Res. 2006 Nov; 26(11):834-8. PMID: 17115902; PMCID: PMC4113398.
  288. Chung RT, Misdraji J, Sahani DV. Case records of the Massachusetts General Hospital. Case 33-2006. A 43-year-old man with diabetes, hypogonadism, cirrhosis, arthralgias, and fatigue. N Engl J Med. 2006 Oct 26; 355(17):1812-9. PMID: 17065644.
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  289. Kim SS, Peng LF, Lin W, Choe WH, Sakamoto N, Kato N, Ikeda M, Schreiber SL, Chung RT. A cell-based, high-throughput screen for small molecule regulators of hepatitis C virus replication. Gastroenterology. 2007 Jan; 132(1):311-20. PMID: 17241881.
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  290. Rutherford A, Davern T, Hay JE, Murray NG, Hassanein T, Lee WM, Chung RT. Influence of high body mass index on outcome in acute liver failure. Clin Gastroenterol Hepatol. 2006 Dec; 4(12):1544-9. PMID: 16996806.
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  291. Lin W, Kim SS, Yeung E, Kamegaya Y, Blackard JT, Kim KA, Holtzman MJ, Chung RT. Hepatitis C virus core protein blocks interferon signaling by interaction with the STAT1 SH2 domain. J Virol. 2006 Sep; 80(18):9226-35. PMID: 16940534; PMCID: PMC1563912.
  292. Corey KE, Ross AS, Wurcel A, Schulze Zur Wiesch J, Kim AY, Lauer GM, Chung RT. Outcomes and treatment of acute hepatitis C virus infection in a United States population. Clin Gastroenterol Hepatol. 2006 Oct; 4(10):1278-82. PMID: 16931171; PMCID: PMC1828916.
  293. Bonkovsky HL, Naishadham D, Lambrecht RW, Chung RT, Hoefs JC, Nash SR, Rogers TE, Banner BF, Sterling RK, Donovan JA, Fontana RJ, Di Bisceglie AM, Ghany MG, Morishima C. Roles of iron and HFE mutations on severity and response to therapy during retreatment of advanced chronic hepatitis C. Gastroenterology. 2006 Nov; 131(5):1440-51. PMID: 17101320.
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  294. Schwarze-Zander C, Blackard JT, Zheng H, Addo MM, Lin W, Robbins GK, Sherman KE, Zdunek D, Hess G, Chung RT. GB virus C (GBV-C) infection in hepatitis C virus (HCV)/HIV-coinfected patients receiving HCV treatment: importance of the GBV-C genotype. J Infect Dis. 2006 Aug 15; 194(4):410-9. PMID: 16845623.
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  295. Basavapathruni A, Vingerhoets J, de Béthune MP, Chung R, Bailey CM, Kim J, Anderson KS. Modulation of human immunodeficiency virus type 1 synergistic inhibition by reverse transcriptase mutations. Biochemistry. 2006 Jun 13; 45(23):7334-40. PMID: 16752922.
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  296. O'Leary JG, Chung RT. Management of hepatitis C virus coinfection in HIV-infected persons. AIDS Read. 2006 Jun; 16(6):313-6, 318-20. PMID: 16795921.
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  297. Chung RT. Hepatitis C and B viruses: the new opportunists in HIV infection. Top HIV Med. 2006 Jun-Jul; 14(2):78-83. PMID: 16835462.
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  298. Chung RT, Iafrate AJ, Amrein PC, Sahani DV, Misdraji J. Case records of the Massachusetts General Hospital. Case 15-2006. A 46-year-old woman with sudden onset of abdominal distention. N Engl J Med. 2006 May 18; 354(20):2166-75. PMID: 16707754.
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  299. Andersson K, Chung RT. Hepatitis C Virus in the HIV-infected patient. Clin Liver Dis. 2006 May; 10(2):303-20, viii. PMID: 16971263.
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  300. Pekow J, Chung RT. Treatment of type II cryoglobulinemia associated with hepatitis C with rituximab. J Clin Gastroenterol. 2006 May-Jun; 40(5):450. PMID: 16721231.
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  301. Fontana RJ, Sanyal AJ, Mehta S, Doherty MC, Neuschwander-Tetri BA, Everson GT, Kahn JA, Malet PF, Sheikh MY, Chung RT, Ghany MG, Gretch DR. Portal hypertensive gastropathy in chronic hepatitis C patients with bridging fibrosis and compensated cirrhosis: results from the HALT-C trial. Am J Gastroenterol. 2006 May; 101(5):983-92. PMID: 16573786.
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  302. Babitt JL, Huang FW, Wrighting DM, Xia Y, Sidis Y, Samad TA, Campagna JA, Chung RT, Schneyer AL, Woolf CJ, Andrews NC, Lin HY. Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nat Genet. 2006 May; 38(5):531-9. PMID: 16604073.
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  303. Graham CS, Wells A, Liu T, Sherman KE, Peters M, Chung RT, Bhan AK, Andersen J, Koziel MJ. Relationships between cellular immune responses and treatment outcomes with interferon and ribavirin in HIV/hepatitis C virus co-infection. AIDS. 2006 Feb 14; 20(3):345-51. PMID: 16439867; PMCID: PMC4060610.
  304. Blackard JT, Komurian-Pradel F, Perret M, Sodoyer M, Smeaton L, St Clair JB, Chapman S, Taylor LE, Paranhos-Baccalà G, Chung RT. Intrahepatic cytokine expression is downregulated during HCV/HIV co-infection. J Med Virol. 2006 Feb; 78(2):202-7. PMID: 16372286.
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  305. Kotton CN, Marconi VC, Fishman JA, Chung RT, Elias N, Hertl M. Coccidioidal meningitis after liver transplantation in a nonendemic region: a case report. Transplantation. 2006 Jan 15; 81(1):132-4. PMID: 16421490.
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  306. Yeung E, Chung RT. Microarrays and prediction of interferon response in chronic hepatitis C: not yet ready for prime time. Clin Gastroenterol Hepatol. 2005 Dec; 3(12):1192-4. PMID: 16361043.
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  307. Schiano TD, Gutierrez JA, Walewski JL, Fiel MI, Cheng B, Bodenheimer H, Thung SN, Chung RT, Schwartz ME, Bodian C, Branch AD. Accelerated hepatitis C virus kinetics but similar survival rates in recipients of liver grafts from living versus deceased donors. Hepatology. 2005 Dec; 42(6):1420-8. PMID: 16317672.
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  308. McGuire BM, Bonkovsky HL, Carithers RL, Chung RT, Goldstein LI, Lake JR, Lok AS, Potter CJ, Rand E, Voigt MD, Davis PR, Bloomer JR. Liver transplantation for erythropoietic protoporphyria liver disease. Liver Transpl. 2005 Dec; 11(12):1590-6. PMID: 16315313.
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  309. Chung RT. Assessment of efficacy of treatment in HCV: infection and disease. J Hepatol. 2006; 44(1 Suppl):S56-9. PMID: 16343683.
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  310. Hiasa Y, Blackard JT, Lin W, Kamegaya Y, Horiike N, Onji M, Schmidt EV, Chung RT. Cell-based models of sustained, interferon-sensitive hepatitis C virus genotype 1 replication. J Virol Methods. 2006 Mar; 132(1-2):195-203. PMID: 16313977; PMCID: PMC2865175.
  311. Morgan L, Neame SJ, Child H, Chung R, Shah B, Barden L, Staddon JM, Patel TR. Development of a pentylenetetrazole-induced seizure model to evaluate kinase inhibitor efficacy in the central nervous system. Neurosci Lett. 2006 Mar 06; 395(2):143-8. PMID: 16300886.
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  312. Graczyk PP, Khan A, Bhatia GS, Palmer V, Medland D, Numata H, Oinuma H, Catchick J, Dunne A, Ellis M, Smales C, Whitfield J, Neame SJ, Shah B, Wilton D, Morgan L, Patel T, Chung R, Desmond H, Staddon JM, Sato N, Inoue A. The neuroprotective action of JNK3 inhibitors based on the 6,7-dihydro-5H-pyrrolo[1,2-a]imidazole scaffold. Bioorg Med Chem Lett. 2005 Nov 01; 15(21):4666-70. PMID: 16153829.
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  313. Schiødt FV, Rossaro L, Stravitz RT, Shakil AO, Chung RT, Lee WM. Gc-globulin and prognosis in acute liver failure. Liver Transpl. 2005 Oct; 11(10):1223-7. PMID: 16184570.
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  314. Lauer GM, Lucas M, Timm J, Ouchi K, Kim AY, Day CL, Schulze Zur Wiesch J, Paranhos-Baccala G, Sheridan I, Casson DR, Reiser M, Gandhi RT, Li B, Allen TM, Chung RT, Klenerman P, Walker BD. Full-breadth analysis of CD8+ T-cell responses in acute hepatitis C virus infection and early therapy. J Virol. 2005 Oct; 79(20):12979-88. PMID: 16189000; PMCID: PMC1235828.
  315. Sekhon JS, Chung RT, Epstein M, Kaplan MM. Steroid-responsive (autoimmune?) sclerosing cholangitis. Dig Dis Sci. 2005 Oct; 50(10):1839-43. PMID: 16187184.
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  316. Schulze zur Wiesch J, Lauer GM, Day CL, Kim AY, Ouchi K, Duncan JE, Wurcel AG, Timm J, Jones AM, Mothe B, Allen TM, McGovern B, Lewis-Ximenez L, Sidney J, Sette A, Chung RT, Walker BD. Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes. J Immunol. 2005 Sep 15; 175(6):3603-13. PMID: 16148104.
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  317. Di Bisceglie AM, Sterling RK, Chung RT, Everhart JE, Dienstag JL, Bonkovsky HL, Wright EC, Everson GT, Lindsay KL, Lok AS, Lee WM, Morgan TR, Ghany MG, Gretch DR. Serum alpha-fetoprotein levels in patients with advanced hepatitis C: results from the HALT-C Trial. J Hepatol. 2005 Sep; 43(3):434-41. PMID: 16136646.
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  318. Yeung E, Chung RT. Rethinking hepatitis C viral kinetics: Insights into host-virus interactions in 'difficult-to-treat' groups and implications for novel treatment approaches. J Hepatol. 2005 Nov; 43(5):748-50. PMID: 16171895.
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  319. Tanabe KK, Blaszkowsky LS, Chung RT, Blake MA, Lauwers GY. Case records of the Massachusetts General Hospital. Case 23-2005. A 57-year-old man with a mass in the liver. N Engl J Med. 2005 Jul 28; 353(4):401-10. PMID: 16049213.
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  320. Chung RT. Acute hepatitis C virus infection. Clin Infect Dis. 2005 Jul 01; 41 Suppl 1:S14-7. PMID: 16265608.
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  321. Yachimski P, Chung RT. Update on Hepatitis B and C Coinfection in HIV. Curr Infect Dis Rep. 2005 Jul; 7(4):299-308. PMID: 15963332.
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  322. Blackard JT, Smeaton L, Hiasa Y, Horiike N, Onji M, Jamieson DJ, Rodriguez I, Mayer KH, Chung RT. Detection of hepatitis C virus (HCV) in serum and peripheral-blood mononuclear cells from HCV-monoinfected and HIV/HCV-coinfected persons. J Infect Dis. 2005 Jul 15; 192(2):258-65. PMID: 15962220.
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  323. Graham CS, Wells A, Liu T, Sherman KE, Peters M, Chung RT, Bhan AK, Andersen J, Koziel MJ. Antigen-specific immune responses and liver histology in HIV and hepatitis C coinfection. AIDS. 2005 May 20; 19(8):767-73. PMID: 15867490; PMCID: PMC4050654.
  324. Yachimski P, Chung RT. Hepatitis B virus infection in liver transplant candidates and recipients. MedGenMed. 2005 Apr 18; 7(2):20. PMID: 16369399; PMCID: PMC1681606.
  325. Lin W, Choe WH, Hiasa Y, Kamegaya Y, Blackard JT, Schmidt EV, Chung RT. Hepatitis C virus expression suppresses interferon signaling by degrading STAT1. Gastroenterology. 2005 Apr; 128(4):1034-41. PMID: 15825084.
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  326. Kamegaya Y, Hiasa Y, Zukerberg L, Fowler N, Blackard JT, Lin W, Choe WH, Schmidt EV, Chung RT. Hepatitis C virus acts as a tumor accelerator by blocking apoptosis in a mouse model of hepatocarcinogenesis. Hepatology. 2005 Mar; 41(3):660-7. PMID: 15723444.
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  327. Chung RT. Cytokine polymorphisms and hepatocellular carcinoma: to B or not to B. Cancer. 2005 Feb 15; 103(4):654-6. PMID: 15641028.
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  328. Sherman KE, Shire NJ, Rouster SD, Peters MG, James Koziel M, Chung RT, Horn PS. Viral kinetics in hepatitis C or hepatitis C/human immunodeficiency virus-infected patients. Gastroenterology. 2005 Feb; 128(2):313-27. PMID: 15685543; PMCID: PMC4036101.
  329. Eichbaum QG, Dzik WH, Chung RT, Szczepiorkowski ZM. Red blood cell exchange transfusion in two patients with advanced erythropoietic protoporphyria. Transfusion. 2005 Feb; 45(2):208-13. PMID: 15660829.
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  330. Yeo H, Li Y, Fu L, Zhu JL, Gullen EA, Dutschman GE, Lee Y, Chung R, Huang ES, Austin DJ, Cheng YC. Synthesis and antiviral activity of helioxanthin analogues. J Med Chem. 2005 Jan 27; 48(2):534-46. PMID: 15658867.
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  331. Hoehne F, Ozaeta M, Chung R. Routine chest X-ray after percutaneous tracheostomy is unnecessary. Am Surg. 2005 Jan; 71(1):51-3. PMID: 15757057.
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  332. Torriani FJ, Chung RT. Peginterferon alpha-2a improved the hepatitis C virologic response in concurrent HIV and chronic hepatitis C virus infections. ACP J Club. 2005 Jan-Feb; 142(1):A12; author reply A13. PMID: 15656540.
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  333. Timm J, Lauer GM, Kavanagh DG, Sheridan I, Kim AY, Lucas M, Pillay T, Ouchi K, Reyor LL, Schulze zur Wiesch J, Gandhi RT, Chung RT, Bhardwaj N, Klenerman P, Walker BD, Allen TM. CD8 epitope escape and reversion in acute HCV infection. J Exp Med. 2004 Dec 20; 200(12):1593-604. PMID: 15611288; PMCID: PMC2212005.
  334. Leung JY, Zhu AX, Gordon FD, Pratt DS, Mithoefer A, Garrigan K, Terella A, Hertl M, Cosimi AB, Chung RT. Liver transplantation outcomes for early-stage hepatocellular carcinoma: results of a multicenter study. Liver Transpl. 2004 Nov; 10(11):1343-54. PMID: 15497158.
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  335. Yachimski P, Chung RT. Editorial comment: erythropoietin for treatment-related anemia in persons with hepatitis C--questions remain. AIDS Read. 2004 Oct; 14(10):568-9. PMID: 15510393.
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  336. Kim AY, Lauer GM, Ouchi K, Addo MM, Lucas M, Schulze Zur Wiesch J, Timm J, Boczanowski M, Duncan JE, Wurcel AG, Casson D, Chung RT, Draenert R, Klenerman P, Walker BD. The magnitude and breadth of hepatitis C virus-specific CD8+ T cells depend on absolute CD4+ T-cell count in individuals coinfected with HIV-1. Blood. 2005 Feb 01; 105(3):1170-8. PMID: 15459014.
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  337. Lauer GM, Barnes E, Lucas M, Timm J, Ouchi K, Kim AY, Day CL, Robbins GK, Casson DR, Reiser M, Dusheiko G, Allen TM, Chung RT, Walker BD, Klenerman P. High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection. Gastroenterology. 2004 Sep; 127(3):924-36. PMID: 15362047.
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  338. Cardarelli F, Pascual M, Chung RT, Tolkoff-Rubin N, Wong W, Cosimi AB, Saidman SL. Interferon-alpha therapy in liver transplant recipients: lack of association with increased production of anti-HLA antibodies. Am J Transplant. 2004 Aug; 4(8):1352-6. PMID: 15268739.
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  339. Chung RT, Andersen J, Volberding P, Robbins GK, Liu T, Sherman KE, Peters MG, Koziel MJ, Bhan AK, Alston B, Colquhoun D, Nevin T, Harb G, van der Horst C. Peginterferon Alfa-2a plus ribavirin versus interferon alfa-2a plus ribavirin for chronic hepatitis C in HIV-coinfected persons. N Engl J Med. 2004 Jul 29; 351(5):451-9. PMID: 15282352; PMCID: PMC4113392.
  340. Ross AS, Bhan AK, Pascual M, Thiim M, Benedict Cosimi A, Chung RT. Pegylated interferon alpha-2b plus ribavirin in the treatment of post-liver transplant recurrent hepatitis C. Clin Transplant. 2004 Apr; 18(2):166-73. PMID: 15016131.
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  341. O'Leary J, Chung RT. New antiviral therapies for hepatitis C. Expert Rev Anti Infect Ther. 2004 Apr; 2(2):235-43. PMID: 15482189.
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  342. Blackard JT, Yang Y, Bordoni P, Sherman KE, Chung RT. Hepatitis C virus (HCV) diversity in HIV-HCV-coinfected subjects initiating highly active antiretroviral therapy. J Infect Dis. 2004 Apr 15; 189(8):1472-81. PMID: 15073685.
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  343. Delgado-Borrego A, Casson D, Schoenfeld D, Somsouk M, Terella A, Jordan SH, Bhan A, Baid S, Cosimi AB, Pascual M, Chung RT. Hepatitis C virus is independently associated with increased insulin resistance after liver transplantation. Transplantation. 2004 Mar 15; 77(5):703-10. PMID: 15021833.
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  344. Kuo A, Dienstag JL, Chung RT. Tenofovir disoproxil fumarate for the treatment of lamivudine-resistant hepatitis B. Clin Gastroenterol Hepatol. 2004 Mar; 2(3):266-72. PMID: 15017612.
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  345. Chung RT, Casson DR, Murray G, Song S, Grinspoon S, Hadigan C. Alanine aminotransferase levels predict insulin resistance in HIV lipodystrophy. J Acquir Immune Defic Syndr. 2003 Dec 15; 34(5):534-6. PMID: 14657767.
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  346. O'Leary J, Chung RT. New antiviral therapies for hepatitis C. Taehan Kan Hakhoe Chi. 2003 Dec; 9(4):265-74. PMID: 14695693.
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  347. Hiasa Y, Kamegaya Y, Nuriya H, Onji M, Kohara M, Schmidt EV, Chung RT. Protein kinase R is increased and is functional in hepatitis C virus-related hepatocellular carcinoma. Am J Gastroenterol. 2003 Nov; 98(11):2528-34. PMID: 14638359.
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  348. Moriguchi H, Chung RT, Contreras AM, Izumi N, Uemura T, Kobayashi M, Sato C. The interferon sensitivity determining region in the era of combination therapies and the rational use of such therapies for patients with HCV genotype 1b infection. Gastroenterology. 2003 Oct; 125(4):1284-6. PMID: 14552320.
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  349. Day CL, Seth NP, Lucas M, Appel H, Gauthier L, Lauer GM, Robbins GK, Szczepiorkowski ZM, Casson DR, Chung RT, Bell S, Harcourt G, Walker BD, Klenerman P, Wucherpfennig KW. Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers. J Clin Invest. 2003 Sep; 112(6):831-42. PMID: 12975468; PMCID: PMC193667.
  350. Zhu AX, Chung RT. Hepatic steatosis in patients with chronic hepatitis C virus infection. Another risk factor for hepatocellular carcinoma? Cancer. 2003 Jun 15; 97(12):2948-50. PMID: 12784328.
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  351. Somsouk M, Lauer GM, Casson D, Terella A, Day CL, Walker BD, Chung RT. Spontaneous resolution of chronic hepatitis C virus disease after withdrawal of immunosuppression. Gastroenterology. 2003 Jun; 124(7):1946-9. PMID: 12806627.
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  352. Leung JY, Abraczinskas DR, Bhan AK, Terella AM, Pascual M, Cosimi AB, Chung RT. Recurrent allograft HCV presenting as acute cellular rejection: successful management with interferon and ribavirin alone. Clin Transplant. 2003 Jun; 17(3):275-83. PMID: 12780680.
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  353. Glehen O, Mithieux F, Traverse-Glehen A, Isaac S, Bienvenu J, François Y, Chung R, Gilly FN. Enteral immunotherapy in the treatment of chronic enterocolitis in interleukin-10-deficient mice. Hepatogastroenterology. 2003 May-Jun; 50(51):670-5. PMID: 12828057.
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  354. Moriguchi H, Kobayashi M, Chung RT, Sato C. Optimal IFN therapy for 40-year-old patients with severe HCV-1b infection. Gastroenterology. 2003 Apr; 124(4):1166-7. PMID: 12671922.
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  355. Baid S, Tolkoff-Rubin N, Saidman S, Chung R, Williams WW, Auchincloss H, Colvin RB, Delmonico FL, Cosimi AB, Pascual M. Acute humoral rejection in hepatitis C-infected renal transplant recipients receiving antiviral therapy. Am J Transplant. 2003 Jan; 3(1):74-8. PMID: 12492714.
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  356. Sikaneta T, Williams WW, Chung RT, Cosimi AB, Pascual AM. Remission of hepatitis C virus-associated cryoglobulinemic glomerulonephritis with interferon alfa-2b and ribavirin combination therapy after liver transplantation. Transplantation. 2002 Dec 27; 74(12):1767-8. PMID: 12499895.
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  357. Goessling W, Chung RT. Amebic Liver Abscess. Curr Treat Options Gastroenterol. 2002 Dec; 5(6):443-449. PMID: 12408781.
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  358. Day CL, Lauer GM, Robbins GK, McGovern B, Wurcel AG, Gandhi RT, Chung RT, Walker BD. Broad specificity of virus-specific CD4+ T-helper-cell responses in resolved hepatitis C virus infection. J Virol. 2002 Dec; 76(24):12584-95. PMID: 12438584; PMCID: PMC136690.
  359. Contreras AM, Chung RT. Hepatitis C virus in solid organ transplantation: not always a bad thing? Gastroenterology. 2002 Nov; 123(5):1729-33. PMID: 12404247.
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  360. Chung RT, Evans SR, Yang Y, Theodore D, Valdez H, Clark R, Shikuma C, Nevin T, Sherman KE. Immune recovery is associated with persistent rise in hepatitis C virus RNA, infrequent liver test flares, and is not impaired by hepatitis C virus in co-infected subjects. AIDS. 2002 Sep 27; 16(14):1915-23. PMID: 12351951.
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  361. Chung RT. New developments in the management of hepatitis B virus/HIV coinfection. MedGenMed. 2002 Sep 03; 4(3):20. PMID: 12466763.
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  362. Contreras AM, Hiasa Y, He W, Terella A, Schmidt EV, Chung RT. Viral RNA mutations are region specific and increased by ribavirin in a full-length hepatitis C virus replication system. J Virol. 2002 Sep; 76(17):8505-17. PMID: 12163570; PMCID: PMC136407.
  363. Moriguchi H, Uemura T, Kobayashi M, Chung RT, Sato C. Management strategies using pharmacogenomics in patients with severe HCV-1b infection: a decision analysis. Hepatology. 2002 Jul; 36(1):177-85. PMID: 12085363.
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  364. Lauer GM, Ouchi K, Chung RT, Nguyen TN, Day CL, Purkis DR, Reiser M, Kim AY, Lucas M, Klenerman P, Walker BD. Comprehensive analysis of CD8(+)-T-cell responses against hepatitis C virus reveals multiple unpredicted specificities. J Virol. 2002 Jun; 76(12):6104-13. PMID: 12021343; PMCID: PMC136241.
  365. Dellon ES, Szczepiorkowski ZM, Dzik WH, Graeme-Cook F, Ades A, Bloomer JR, Cosimi AB, Chung RT. Treatment of recurrent allograft dysfunction with intravenous hematin after liver transplantation for erythropoietic protoporphyria. Transplantation. 2002 Mar 27; 73(6):911-5. PMID: 11923691.
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  366. Lauer GM, Nguyen TN, Day CL, Robbins GK, Flynn T, McGowan K, Rosenberg ES, Lucas M, Klenerman P, Chung RT, Walker BD. Human immunodeficiency virus type 1-hepatitis C virus coinfection: intraindividual comparison of cellular immune responses against two persistent viruses. J Virol. 2002 Mar; 76(6):2817-26. PMID: 11861849; PMCID: PMC135971.
  367. Ross AS, Graeme-Cook F, Cosimi AB, Chung RT. Combined liver and kidney transplantation in a patient with sickle cell disease. Transplantation. 2002 Feb 27; 73(4):605-8. PMID: 11889439.
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  368. Sherman KE, Rouster SD, Chung RT, Rajicic N. Hepatitis C Virus prevalence among patients infected with Human Immunodeficiency Virus: a cross-sectional analysis of the US adult AIDS Clinical Trials Group. Clin Infect Dis. 2002 Mar 15; 34(6):831-7. PMID: 11833007.
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  369. Rosenberg PM, Farrell JJ, Abraczinskas DR, Graeme-Cook FM, Dienstag JL, Chung RT. Rapidly progressive fibrosing cholestatic hepatitis--hepatitis C virus in HIV coinfection. Am J Gastroenterol. 2002 Feb; 97(2):478-83. PMID: 11866292.
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  370. Baid S, Cosimi AB, Farrell ML, Schoenfeld DA, Feng S, Chung RT, Tolkoff-Rubin N, Pascual M. Posttransplant diabetes mellitus in liver transplant recipients: risk factors, temporal relationship with hepatitis C virus allograft hepatitis, and impact on mortality. Transplantation. 2001 Sep 27; 72(6):1066-72. PMID: 11579302.
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  371. Chung RT, He W, Saquib A, Contreras AM, Xavier RJ, Chawla A, Wang TC, Schmidt EV. Hepatitis C virus replication is directly inhibited by IFN-alpha in a full-length binary expression system. Proc Natl Acad Sci U S A. 2001 Aug 14; 98(17):9847-52. PMID: 11493707; PMCID: PMC55541.
  372. Chung RT, Feng S, Delmonico FL. Approach to the management of allograft recipients following the detection of hepatitis B virus in the prospective organ donor. Am J Transplant. 2001 Jul; 1(2):185-91. PMID: 12099368.
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  373. Wong DK, Dudley DD, Dohrenwend PB, Lauer GM, Chung RT, Thomas DL, Walker BD. Detection of diverse hepatitis C virus (HCV)-specific cytotoxic T lymphocytes in peripheral blood of infected persons by screening for responses to all translated proteins of HCV. J Virol. 2001 Feb; 75(3):1229-35. PMID: 11152496; PMCID: PMC114029.
  374. Chung RT, Kim AY, Polsky B. HIV/Hepatitis B and C co-infection: pathogenic interactions, natural history and therapy. Antivir Chem Chemother. 2001; 12 Suppl 1:73-91. PMID: 11594692.
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  375. Lo SC, Levin L, Ribas J, Chung R, Wang RY, Wear D, Shih JW. Lack of serological evidence for Mycoplasma fermentans infection in army Gulf War veterans: a large scale case-control study. Epidemiol Infect. 2000 Dec; 125(3):609-16. PMID: 11218212; PMCID: PMC2869645.
  376. Abraczinskas DR, Chung RT. Allograft dysfunction and hyperbilirubinemia in a liver transplant recipient. Transpl Infect Dis. 2000 Dec; 2(4):186-93. PMID: 11429030.
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  377. Farrell JJ, Cosimi AB, Chung RT. Idiopathic giant esophageal ulcers in a renal transplant patient responsive to steroid therapy. Transplantation. 2000 Jul 15; 70(1):230-2. PMID: 10919611.
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  378. Lechner F, Wong DK, Dunbar PR, Chapman R, Chung RT, Dohrenwend P, Robbins G, Phillips R, Klenerman P, Walker BD. Analysis of successful immune responses in persons infected with hepatitis C virus. J Exp Med. 2000 May 01; 191(9):1499-512. PMID: 10790425; PMCID: PMC2213430.
  379. Abrahamian GA, Cosimi AB, Farrell ML, Schoenfeld DA, Chung RT, Pascual M. Prevalence of hepatitis C virus-associated mixed cryoglobulinemia after liver transplantation. Liver Transpl. 2000 Mar; 6(2):185-90. PMID: 10719018.
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  380. Kim AY, Chung RT, Polsky B. Human immunodeficiency virus and hepatitis B and C coinfection: pathogenic interactions, natural history, and therapy. AIDS Clin Rev. 2000-2001; 263-306. PMID: 10999223.
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  381. Baid S, Pascual M, Cosimi AB, Chung RT, Colvin RB, Tolkoff-Rubin N. Viruses and thrombotic microangiopathy. Transplantation. 1999 Sep 15; 68(5):710-1. PMID: 10507496.
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  382. Chung RT, Monto A, Dienstag JL, Kaplan LM. Mutations in the NS5A region do not predict interferon-responsiveness in american patients infected with genotype 1b hepatitis C virus. J Med Virol. 1999 Aug; 58(4):353-8. PMID: 10421401.
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  383. Chung RT, Kaplan LM. Heterogeneous nuclear ribonucleoprotein I (hnRNP-I/PTB) selectively binds the conserved 3' terminus of hepatitis C viral RNA. Biochem Biophys Res Commun. 1999 Jan 19; 254(2):351-62. PMID: 9918842.
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  384. Baid S, Pascual M, Williams WW, Tolkoff-Rubin N, Johnson SM, Collins B, Chung RT, Delmonico FL, Cosimi AB, Colvin RB. Renal thrombotic microangiopathy associated with anticardiolipin antibodies in hepatitis C-positive renal allograft recipients. J Am Soc Nephrol. 1999 Jan; 10(1):146-53. PMID: 9890320.
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  385. Chung WS, Cho C, Kim S, Wang Y, Lee S, Tarin T, Chung R, Housman L, Jamieson SW. Review of significant microvascular surgical breakthroughs involving the heart and lungs in rats. Microsurgery. 1999; 19(2):71-7. PMID: 10188829.
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  386. Toth CM, Pascual M, Chung RT, Graeme-Cook F, Dienstag JL, Bhan AK, Cosimi AB. Hepatitis C virus-associated fibrosing cholestatic hepatitis after renal transplantation: response to interferon-alpha therapy. Transplantation. 1998 Nov 15; 66(9):1254-8. PMID: 9825826.
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  387. Oldfield EC, Fessel WJ, Dunne MW, Dickinson G, Wallace MR, Byrne W, Chung R, Wagner KF, Paparello SF, Craig DB, Melcher G, Zajdowicz M, Williams RF, Kelly JW, Zelasky M, Heifets LB, Berman JD. Once weekly azithromycin therapy for prevention of Mycobacterium avium complex infection in patients with AIDS: a randomized, double-blind, placebo-controlled multicenter trial. Clin Infect Dis. 1998 Mar; 26(3):611-9. PMID: 9524832.
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  388. Pascual M, Thadhani R, Chung RT, Williams WW, Meehan S, Tolkoff-Rubin N, Colvin R, Cosimi AB. Nephrotic syndrome after liver transplantation in a patient with hepatitis C virus-associated glomerulonephritis. Transplantation. 1997 Oct 15; 64(7):1073-6. PMID: 9381532.
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  389. Kawamura T, Furusaka A, Koziel MJ, Chung RT, Wang TC, Schmidt EV, Liang TJ. Transgenic expression of hepatitis C virus structural proteins in the mouse. Hepatology. 1997 Apr; 25(4):1014-21. PMID: 9096613.
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  390. Jaffe DL, Chung RT, Friedman LS. Management of portal hypertension and its complications. Med Clin North Am. 1996 Sep; 80(5):1021-34. PMID: 8804373.
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  391. Obeid F, Saba A, Fath J, Guslits B, Chung R, Sorensen V, Buck J, Horst M. Increases in intra-abdominal pressure affect pulmonary compliance. Arch Surg. 1995 May; 130(5):544-7; discussion 547-8. PMID: 7748095.
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  392. Brown AE, Lane JR, Wagner KF, Zhou S, Chung R, Ray KL, Blatt SP, Burke DS. Rates of p24 antigenemia and viral isolation in comparable white and black HIV-infected subjects. Military Medical Consortium for Applied Retroviral Research. AIDS. 1995 Apr; 9(4):325-8. PMID: 7794537.
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  393. Chung RT, Jaffe DL, Friedman LS. Complications of chronic liver disease. Crit Care Clin. 1995 Apr; 11(2):431-63. PMID: 7788540.
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  394. Chung RT. Just say "NO" to viral hepatitis? Hepatology. 1994 Mar; 19(3):790-2. PMID: 7509773.
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  395. Mayers DL, Japour AJ, Arduino JM, Hammer SM, Reichman R, Wagner KF, Chung R, Lane J, Crumpacker CS, McLeod GX, et al. Dideoxynucleoside resistance emerges with prolonged zidovudine monotherapy. The RV43 Study Group. Antimicrob Agents Chemother. 1994 Feb; 38(2):307-14. PMID: 8192457; PMCID: PMC284445.
  396. Schmaier AH, Dahl LD, Rozemuller AJ, Roos RA, Wagner SL, Chung R, Van Nostrand WE. Protease nexin-2/amyloid beta protein precursor. A tight-binding inhibitor of coagulation factor IXa. J Clin Invest. 1993 Nov; 92(5):2540-5. PMID: 8227367; PMCID: PMC288440.
  397. Chung RT, Schapiro RH, Warshaw AL. Intraluminal pancreatic candidiasis presenting as recurrent pancreatitis. Gastroenterology. 1993 May; 104(5):1532-4. PMID: 8482466.
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  398. Chung RT, Kaplan LM. Parenterally transmitted hepatitis: viruses, vaccines, and antiviral therapy. Compr Ther. 1993; 19(4):163-73. PMID: 7505215.
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  399. Agnello V, Chung RT, Kaplan LM. A role for hepatitis C virus infection in type II cryoglobulinemia. N Engl J Med. 1992 Nov 19; 327(21):1490-5. PMID: 1383822.
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  400. Chung R, Whaley J, Kley N, Anderson K, Louis D, Menon A, Hettlich C, Freiman R, Hedley-Whyte ET, Martuza R, et al. TP53 gene mutations and 17p deletions in human astrocytomas. Genes Chromosomes Cancer. 1991 Sep; 3(5):323-31. PMID: 1686725.
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  401. Tramont EC, Chung R, Berman S, Keren D, Kapfer C, Formal SB. Safety and antigenicity of typhoid-Shigella sonnei vaccine (strain 5076-1C). J Infect Dis. 1984 Feb; 149(2):133-6. PMID: 6366077.
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  402. Chung R, Lewis JW. Cost of treatment of bleeding esophageal varices. Arch Surg. 1983 Apr; 118(4):482-5. PMID: 6830439.
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