Harvard Catalyst Profiles

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Daniel Francis Dwyer, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K22AI146281 (DWYER, DANIEL F) Aug 13, 2020 - Jul 31, 2022
    Oxysterol Regulation of Mast Cell Biology
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ben-Baruch Morgenstern N, Ballaban AY, Wen T, Shoda T, Caldwell JM, Kliewer K, Felton JM, Abonia JP, Mukkada VA, Putnam PE, Bolton SM, Dwyer DF, Barrett NA, Rothenberg ME. Single-cell RNA sequencing of mast cells in eosinophilic esophagitis reveals heterogeneity, local proliferation and activation that persists in remission. J Allergy Clin Immunol. 2022 Mar 15. PMID: 35304158.
    Citations:    Fields:    
  2. Balestrieri B, Di Costanzo D, Dwyer DF. Macrophage-Mediated Immune Responses: From Fatty Acids to Oxylipins. Molecules. 2021 Dec 28; 27(1). PMID: 35011385.
    Citations:    Fields:    Translation:HumansAnimalsCells
  3. Yang Y, Akhondi-Asl A, Geva A, Dwyer D, Stickney C, Kleinman ME, Madden K, Sanderson A, Mehta NM. Implementation of an Analgesia-Sedation Protocol Is Associated With Reduction in Midazolam Usage in the PICU. Pediatr Crit Care Med. 2021 10 01; 22(10):e513-e523. PMID: 33852546.
    Citations:    Fields:    Translation:Humans
  4. Dwyer DF, Austen KF. The Discovery of Discrete Developmental Pathways Directing Constitutive and Induced Mast Cells in Mice. J Immunol. 2021 07 15; 207(2):359-361. PMID: 34644258.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  5. Dwyer DF, Boyce JA. Reply. J Allergy Clin Immunol. 2021 09; 148(3):904. PMID: 34183166.
    Citations:    Fields:    
  6. Buchheit KM, Lewis E, Gakpo D, Hacker J, Sohail A, Taliaferro F, Berreondo Giron E, Asare C, Vukovic M, Bensko JC, Dwyer DF, Shalek AK, Ordovas-Montanes J, Laidlaw TM. Mepolizumab targets multiple immune cells in aspirin-exacerbated respiratory disease. J Allergy Clin Immunol. 2021 08; 148(2):574-584. PMID: 34144111.
    Citations: 3     Fields:    Translation:HumansCellsCTClinical Trials
  7. Dwyer DF, Boyce JA. Neonatal mast cells and transplacental IgE transfer: A mechanism of disease inheritance or of passive infant barrier defense? J Allergy Clin Immunol. 2021 07; 148(1):76-77. PMID: 33872654.
    Citations: 1     Fields:    Translation:HumansCells
  8. Gotlib J, George TI, Carter MC, Austen KF, Bochner B, Dwyer DF, Lyons JJ, Hamilton MJ, Butterfield J, Bonadonna P, Weiler C, Galli SJ, Schwartz LB, Elberink HO, Maitland A, Theoharides T, Ustun C, Horny HP, Orfao A, Deininger M, Radia D, Jawhar M, Kluin-Nelemans H, Metcalfe DD, Arock M, Sperr WR, Valent P, Castells M, Akin C. Proceedings from the Inaugural American Initiative in Mast Cell Diseases (AIM) Investigator Conference. J Allergy Clin Immunol. 2021 06; 147(6):2043-2052. PMID: 33745886.
    Citations: 2     Fields:    Translation:Humans
  9. Dwyer DF, Ordovas-Montanes J, Allon SJ, Buchheit KM, Vukovic M, Derakhshan T, Feng C, Lai J, Hughes TK, Nyquist SK, Giannetti MP, Berger B, Bhattacharyya N, Roditi RE, Katz HR, Nawijn MC, Berg M, van den Berge M, Laidlaw TM, Shalek AK, Barrett NA, Boyce JA. Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation. Sci Immunol. 2021 02 26; 6(56). PMID: 33637594.
    Citations: 7     Fields:    Translation:HumansCells
  10. Giannetti MP, Weller E, Alvarez-Twose I, Torrado I, Bonadonna P, Zanotti R, Dwyer DF, Foer D, Akin C, Hartmann K, Rama TA, Sperr WR, Valent P, Teodosio C, Orfao A, Castells M. COVID-19 infection in patients with mast cell disorders including mastocytosis does not impact mast cell activation symptoms. J Allergy Clin Immunol Pract. 2021 05; 9(5):2083-2086. PMID: 33631409.
    Citations: 2     Fields:    Translation:HumansCells
  11. Dwyer DF. Eicosanoid relay: Epithelial and mast cell transmetabolism in AERD. J Allergy Clin Immunol. 2021 02; 147(2):501-503. PMID: 33358894.
    Citations:    Fields:    Translation:HumansCells
  12. Derakhshan T, Samuchiwal SK, Hallen N, Bankova LG, Boyce JA, Barrett NA, Austen KF, Dwyer DF. Lineage-specific regulation of inducible and constitutive mast cells in allergic airway inflammation. J Exp Med. 2021 01 04; 218(1). PMID: 32946563.
    Citations: 3     Fields:    Translation:AnimalsCells
  13. Martin HC, Derakhshan T, Dwyer DF. Insights into mast cell hyperplasia in aspirin-exacerbated respiratory disease from transcriptional profiling of polyp mast cells. Ann Allergy Asthma Immunol. 2021 02; 126(2):120-121. PMID: 33161153.
    Citations: 1     Fields:    Translation:HumansCells
  14. Melendez E, Dwyer D, Donelly D, Currier D, Nachreiner D, Miller DM, Hurlbut J, Pepin MJ, Agus MSD, Wong J. Standardized Protocol Is Associated With a Decrease in Continuous Albuterol Use and Length of Stay in Critical Status Asthmaticus. Pediatr Crit Care Med. 2020 05; 21(5):451-460. PMID: 32084098.
    Citations: 1     Fields:    Translation:Humans
  15. Ziegler CGK, Allon SJ, Nyquist SK, Mbano IM, Miao VN, Tzouanas CN, Cao Y, Yousif AS, Bals J, Hauser BM, Feldman J, Muus C, Wadsworth MH, Kazer SW, Hughes TK, Doran B, Gatter GJ, Vukovic M, Taliaferro F, Mead BE, Guo Z, Wang JP, Gras D, Plaisant M, Ansari M, Angelidis I, Adler H, Sucre JMS, Taylor CJ, Lin B, Waghray A, Mitsialis V, Dwyer DF, Buchheit KM, Boyce JA, Barrett NA, Laidlaw TM, Carroll SL, Colonna L, Tkachev V, Peterson CW, Yu A, Zheng HB, Gideon HP, Winchell CG, Lin PL, Bingle CD, Snapper SB, Kropski JA, Theis FJ, Schiller HB, Zaragosi LE, Barbry P, Leslie A, Kiem HP, Flynn JL, Fortune SM, Berger B, Finberg RW, Kean LS, Garber M, Schmidt AG, Lingwood D, Shalek AK, Ordovas-Montanes J. SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues. Cell. 2020 05 28; 181(5):1016-1035.e19. PMID: 32413319.
    Citations: 859     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  16. Buchheit KM, Dwyer DF, Ordovas-Montanes J, Katz HR, Lewis E, Vukovic M, Lai J, Bankova LG, Bhattacharyya N, Shalek AK, Barrett NA, Boyce JA, Laidlaw TM. IL-5Ra marks nasal polyp IgG4- and IgE-expressing cells in aspirin-exacerbated respiratory disease. J Allergy Clin Immunol. 2020 06; 145(6):1574-1584. PMID: 32199912.
    Citations: 9     Fields:    Translation:HumansCells
  17. Bankova LG, Dwyer DF, Yoshimoto E, Ualiyeva S, McGinty JW, Raff H, von Moltke J, Kanaoka Y, Frank Austen K, Barrett NA. The cysteinyl leukotriene 3 receptor regulates expansion of IL-25-producing airway brush cells leading to type 2 inflammation. Sci Immunol. 2018 10 05; 3(28). PMID: 30291131.
    Citations: 39     Fields:    Translation:AnimalsCells
  18. Ordovas-Montanes J, Dwyer DF, Nyquist SK, Buchheit KM, Vukovic M, Deb C, Wadsworth MH, Hughes TK, Kazer SW, Yoshimoto E, Cahill KN, Bhattacharyya N, Katz HR, Berger B, Laidlaw TM, Boyce JA, Barrett NA, Shalek AK. Allergic inflammatory memory in human respiratory epithelial progenitor cells. Nature. 2018 08; 560(7720):649-654. PMID: 30135581.
    Citations: 90     Fields:    Translation:HumansCells
  19. Henry EK, Sy CB, Inclan-Rico JM, Espinosa V, Ghanny SS, Dwyer DF, Soteropoulos P, Rivera A, Siracusa MC. Carbonic anhydrase enzymes regulate mast cell-mediated inflammation. J Exp Med. 2016 08 22; 213(9):1663-73. PMID: 27526715.
    Citations: 11     Fields:    Translation:AnimalsCells
  20. Dwyer DF, Barrett NA, Austen KF. Expression profiling of constitutive mast cells reveals a unique identity within the immune system. Nat Immunol. 2016 Jul; 17(7):878-87. PMID: 27135604.
    Citations: 121     Fields:    Translation:AnimalsCells
  21. Bankova LG, Dwyer DF, Liu AY, Austen KF, Gurish MF. Maturation of mast cell progenitors to mucosal mast cells during allergic pulmonary inflammation in mice. Mucosal Immunol. 2015 May; 8(3):596-606. PMID: 25291985.
    Citations: 29     Fields:    Translation:AnimalsCells
  22. Dwyer DF, Woodruff MC, Carroll MC, Austen KF, Gurish MF. B cells regulate CD4+ T cell responses to papain following B cell receptor-independent papain uptake. J Immunol. 2014 Jul 15; 193(2):529-39. PMID: 24928991.
    Citations: 7     Fields:    Translation:AnimalsCellsPHPublic Health
  23. Liu AY, Dwyer DF, Jones TG, Bankova LG, Shen S, Katz HR, Austen KF, Gurish MF. Mast cells recruited to mesenteric lymph nodes during helminth infection remain hypogranular and produce IL-4 and IL-6. J Immunol. 2013 Feb 15; 190(4):1758-66. PMID: 23319739.
    Citations: 9     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.