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profileAruna Das Pradhan, M.D.

TitleAssistant Professor of Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressBrigham and Women's Hospital
Cardiology
75 Francis St
Boston MA 02115
Phone617/732-4965
Fax617/731-3843
vCardDownload vCard (login for email)

Collapse Mentoring 
Collapse completed student projects
Epidemiology Cardiovascular Research
Summer, 06/23/14 - 08/15/14

Collapse Research 
Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R01HL122158     (PRADHAN, ARUNA DAS)Aug 15, 2014 - May 31, 2018
NIH/NHLBI
Anti-inflammatory Therapy with Low Dose Methotrexate for Reduction of PAD
Role: Principal Investigator

R01DK088078     (PRADHAN, ARUNA DAS)Sep 15, 2010 - Jun 30, 2015
NIH/NIDDK
Diabetes Prevention in the Vitamin D and Omega-3 Trial
Role: Principal Investigator

R01HL103742     (PRADHAN, ARUNA DAS)Aug 14, 2010 - Jun 30, 2014
NIH/NHLBI
Mechanisms of Statin-Induced DM in JUPITER (Rosuvasatin for CVD Prevention)
Role: Principal Investigator

K08HL082740     (PRADHAN, ARUNA DAS)Mar 20, 2006 - Feb 28, 2012
NIH/NHLBI
Novel and Traditional Risk Factors for Symptomatic PAD in Women
Role: Principal Investigator

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Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Patel RB, Moorthy MV, Chiuve SE, Pradhan AD, Cook NR, Albert CM. Hemoglobin A1c levels and risk of sudden cardiac death: A nested case-control study. Heart Rhythm. 2017 Jan; 14(1):72-78. PMID: 27591826.
    View in: PubMed
  2. Kilpeläinen TO, Carli JF, Skowronski AA, Sun Q, Kriebel J, Feitosa MF, Hedman ÅK, Drong AW, Hayes JE, Zhao J, Pers TH, Schick U, Grarup N, Kutalik Z, Trompet S, Mangino M, Kristiansson K, Beekman M, Lyytikäinen LP, Eriksson J, Henneman P, Lahti J, Tanaka T, Luan J, Del Greco M F, Pasko D, Renström F, Willems SM, Mahajan A, Rose LM, Guo X, Liu Y, Kleber ME, Pérusse L, Gaunt T, Ahluwalia TS, Ju Sung Y, Ramos YF, Amin N, Amuzu A, Barroso I, Bellis C, Blangero J, Buckley BM, Böhringer S, I Chen YD, de Craen AJ, Crosslin DR, Dale CE, Dastani Z, Day FR, Deelen J, Delgado GE, Demirkan A, Finucane FM, Ford I, Garcia ME, Gieger C, Gustafsson S, Hallmans G, Hankinson SE, Havulinna AS, Herder C, Hernandez D, Hicks AA, Hunter DJ, Illig T, Ingelsson E, Ioan-Facsinay A, Jansson JO, Jenny NS, Jørgensen ME, Jørgensen T, Karlsson M, Koenig W, Kraft P, Kwekkeboom J, Laatikainen T, Ladwig KH, LeDuc CA, Lowe G, Lu Y, Marques-Vidal P, Meisinger C, Menni C, Morris AP, Myers RH, Männistö S, Nalls MA, Paternoster L, Peters A, Pradhan AD, Rankinen T, Rasmussen-Torvik LJ, Rathmann W, Rice TK, Brent Richards J, Ridker PM, Sattar N, Savage DB, Söderberg S, Timpson NJ, Vandenput L, van Heemst D, Uh HW, Vohl MC, Walker M, Wichmann HE, Widén E, Wood AR, Yao J, Zeller T, Zhang Y, Meulenbelt I, Kloppenburg M, Astrup A, Sørensen TI, Sarzynski MA, Rao DC, Jousilahti P, Vartiainen E, Hofman A, Rivadeneira F, Uitterlinden AG, Kajantie E, Osmond C, Palotie A, Eriksson JG, Heliövaara M, Knekt PB, Koskinen S, Jula A, Perola M, Huupponen RK, Viikari JS, Kähönen M, Lehtimäki T, Raitakari OT, Mellström D, Lorentzon M, Casas JP, Bandinelli S, März W, Isaacs A, van Dijk KW, van Duijn CM, Harris TB, Bouchard C, Allison MA, Chasman DI, Ohlsson C, Lind L, Scott RA, Langenberg C, Wareham NJ, Ferrucci L, Frayling TM, Pramstaller PP, Borecki IB, Waterworth DM, Bergmann S, Waeber G, Vollenweider P, Vestergaard H, Hansen T, Pedersen O, Hu FB, Eline Slagboom P, Grallert H, Spector TD, Jukema JW, Klein RJ, Schadt EE, Franks PW, Lindgren CM, Leibel RL, Loos RJ. Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. Nat Commun. 2016 Feb 01; 7:10494. PMID: 26833098; PMCID: PMC4740377.
  3. Srivastava PK, Pradhan AD, Cook NR, Ridker PM, Everett BM. Impact of Modifiable Risk Factors on B-type Natriuretic Peptide and Cardiac Troponin T Concentrations. Am J Cardiol. 2016 Feb 01; 117(3):376-81. PMID: 26739393; PMCID: PMC4743250 [Available on 02/01/17].
  4. Everett BM, Ridker PM, Cook NR, Pradhan AD. Usefulness of B-type Natriuretic Peptides to Predict Cardiovascular Events in Women (from the Women's Health Study). Am J Cardiol. 2015 Aug 15; 116(4):532-7. PMID: 26081066; PMCID: PMC4586028 [Available on 08/15/16].
  5. Akinkuolie AO, Pradhan AD, Buring JE, Ridker PM, Mora S. Novel protein glycan side-chain biomarker and risk of incident type 2 diabetes mellitus. Arterioscler Thromb Vasc Biol. 2015 Jun; 35(6):1544-50. PMID: 25908766; PMCID: PMC4441588 [Available on 06/01/16].
  6. Pradhan AD, Manson JE. Update on the Vitamin D and OmegA-3 trial (VITAL). J Steroid Biochem Mol Biol. 2016 Jan; 155(Pt B):252-6. PMID: 25864623.
    View in: PubMed
  7. Sandhu RK, Conen D, Tedrow UB, Fitzgerald KC, Pradhan AD, Ridker PM, Glynn RJ, Albert CM. Predisposing factors associated with development of persistent compared with paroxysmal atrial fibrillation. J Am Heart Assoc. 2014 May 01; 3(3):e000916. PMID: 24786144; PMCID: PMC4309092.
  8. Pradhan AD. Sex differences in the metabolic syndrome: implications for cardiovascular health in women. Clin Chem. 2014 Jan; 60(1):44-52. PMID: 24255079.
    View in: PubMed
  9. Everett BM, Pradhan AD, Solomon DH, Paynter N, Macfadyen J, Zaharris E, Gupta M, Clearfield M, Libby P, Hasan AA, Glynn RJ, Ridker PM. Rationale and design of the Cardiovascular Inflammation Reduction Trial: a test of the inflammatory hypothesis of atherothrombosis. Am Heart J. 2013 Aug; 166(2):199-207.e15. PMID: 23895801; PMCID: PMC3888829.
  10. Everett BM, Cook NR, Chasman DI, Magnone MC, Bobadilla M, Rifai N, Ridker PM, Pradhan AD. Prospective evaluation of B-type natriuretic peptide concentrations and the risk of type 2 diabetes in women. Clin Chem. 2013 Mar; 59(3):557-65. PMID: 23288489; PMCID: PMC3694412.
  11. Schoen T, Pradhan AD, Albert CM, Conen D. Type 2 diabetes mellitus and risk of incident atrial fibrillation in women. J Am Coll Cardiol. 2012 Oct 09; 60(15):1421-8. PMID: 22981550; PMCID: PMC4277997.
  12. Ridker PM, Pradhan A, MacFadyen JG, Libby P, Glynn RJ. Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from the JUPITER trial. Lancet. 2012 Aug 11; 380(9841):565-71. PMID: 22883507; PMCID: PMC3774022.
  13. Burch RC, Rist PM, Winter AC, Buring JE, Pradhan AD, Loder EW, Kurth T. Migraine and risk of incident diabetes in women: a prospective study. Cephalalgia. 2012 Oct; 32(13):991-7. PMID: 22807568; PMCID: PMC3460043.
  14. de Koning L, Liptak C, Shkreta A, Bradwin G, Hu FB, Pradhan AD, Rifai N, Kellogg MD. A multiplex immunoassay gives different results than singleplex immunoassays which may bias epidemiologic associations. Clin Biochem. 2012 Jul; 45(10-11):848-51. PMID: 22537455.
    View in: PubMed
  15. Lee TC, Glynn RJ, Peña JM, Paynter NP, Conen D, Ridker PM, Pradhan AD, Buring JE, Albert MA. Socioeconomic status and incident type 2 diabetes mellitus: data from the Women's Health Study. PLoS One. 2011; 6(12):e27670. PMID: 22194788; PMCID: PMC3237410.
  16. Ho DY, Cook NR, Britton KA, Kim E, Creager MA, Ridker PM, Pradhan AD. High-molecular-weight and total adiponectin levels and incident symptomatic peripheral artery disease in women: a prospective investigation. Circulation. 2011 Nov 22; 124(21):2303-11. PMID: 22025604; PMCID: PMC3256987.
  17. Paynter NP, Mazer NA, Pradhan AD, Gaziano JM, Ridker PM, Cook NR. Cardiovascular risk prediction in diabetic men and women using hemoglobin A1c vs diabetes as a high-risk equivalent. Arch Intern Med. 2011 Oct 24; 171(19):1712-8. PMID: 21788538; PMCID: PMC3202025.
  18. Powell TM, Glynn RJ, Buring JE, Creager MA, Ridker PM, Pradhan AD. The relative importance of systolic versus diastolic blood pressure control and incident symptomatic peripheral artery disease in women. Vasc Med. 2011 Aug; 16(4):239-46. PMID: 21730007; PMCID: PMC3154540.
  19. Conen D, Everett BM, Kurth T, Creager MA, Buring JE, Ridker PM, Pradhan AD. Smoking, smoking cessation, [corrected] and risk for symptomatic peripheral artery disease in women: a cohort study. Ann Intern Med. 2011 Jun 07; 154(11):719-26. PMID: 21646555; PMCID: PMC3111942.
  20. Everett BM, Cook NR, Magnone MC, Bobadilla M, Kim E, Rifai N, Ridker PM, Pradhan AD. Sensitive cardiac troponin T assay and the risk of incident cardiovascular disease in women with and without diabetes mellitus: the Women's Health Study. Circulation. 2011 Jun 21; 123(24):2811-8. PMID: 21632491; PMCID: PMC3144564.
  21. Britton KA, Pradhan AD, Gaziano JM, Manson JE, Ridker PM, Buring JE, Sesso HD. Hemoglobin A1c, body mass index, and the risk of hypertension in women. Am J Hypertens. 2011 Mar; 24(3):328-34. PMID: 21151012; PMCID: PMC3113494.
  22. Mora S, Otvos JD, Rosenson RS, Pradhan A, Buring JE, Ridker PM. Lipoprotein particle size and concentration by nuclear magnetic resonance and incident type 2 diabetes in women. Diabetes. 2010 May; 59(5):1153-60. PMID: 20185808; PMCID: PMC2857895.
  23. Pradhan AD, Everett BM, Cook NR, Rifai N, Ridker PM. Effects of initiating insulin and metformin on glycemic control and inflammatory biomarkers among patients with type 2 diabetes: the LANCET randomized trial. JAMA. 2009 Sep 16; 302(11):1186-94. PMID: 19755697.
    View in: PubMed
  24. Conen D, Rexrode KM, Creager MA, Ridker PM, Pradhan AD. Metabolic syndrome, inflammation, and risk of symptomatic peripheral artery disease in women: a prospective study. Circulation. 2009 Sep 22; 120(12):1041-7. PMID: 19738135; PMCID: PMC2763563.
  25. Goulart AC, Zee RY, Pradhan A, Rexrode KM. Associations of the estrogen receptors 1 and 2 gene polymorphisms with the metabolic syndrome in women. Metab Syndr Relat Disord. 2009 Apr; 7(2):111-7. PMID: 19032032; PMCID: PMC2674981.
  26. Pradhan AD, Cook NR, Manson JE, Ridker PM, Buring JE. A randomized trial of low-dose aspirin in the prevention of clinical type 2 diabetes in women. Diabetes Care. 2009 Jan; 32(1):3-8. PMID: 18835953; PMCID: PMC2606820.
  27. Neilan TG, Pradhan AD, King ME, Weyman AE. Derivation of a size-independent variable for scaling of cardiac dimensions in a normal paediatric population. Eur J Echocardiogr. 2009 Jan; 10(1):50-5. PMID: 18490317; PMCID: PMC2724882.
  28. Neilan TG, Pradhan AD, Weyman AE. Derivation of a size-independent variable for scaling of cardiac dimensions in a normal adult population. J Am Soc Echocardiogr. 2008 Jul; 21(7):779-85. PMID: 18329846.
    View in: PubMed
  29. Pradhan AD, Shrivastava S, Cook NR, Rifai N, Creager MA, Ridker PM. Symptomatic peripheral arterial disease in women: nontraditional biomarkers of elevated risk. Circulation. 2008 Feb 12; 117(6):823-31. PMID: 18227386.
    View in: PubMed
  30. Pradhan A. Obesity, metabolic syndrome, and type 2 diabetes: inflammatory basis of glucose metabolic disorders. Nutr Rev. 2007 Dec; 65(12 Pt 2):S152-6. PMID: 18240540.
    View in: PubMed
  31. Morrow DA, Wang Y, Croce K, Sakuma M, Sabatine MS, Gao H, Pradhan AD, Healy AM, Buros J, McCabe CH, Libby P, Cannon CP, Braunwald E, Simon DI. Myeloid-related protein 8/14 and the risk of cardiovascular death or myocardial infarction after an acute coronary syndrome in the Pravastatin or Atorvastatin Evaluation and Infection Therapy: Thrombolysis in Myocardial Infarction (PROVE IT-TIMI 22) trial. Am Heart J. 2008 Jan; 155(1):49-55. PMID: 18082488; PMCID: PMC2645040.
  32. Ding EL, Song Y, Manson JE, Pradhan AD, Buring JE, Liu S. Accuracy of administrative coding for type 2 diabetes in children, adolescents, and young adults. Diabetes Care. 2007 Sep; 30(9):e98; author reply e99. PMID: 17726188.
    View in: PubMed
  33. Pradhan AD, Rifai N, Buring JE, Ridker PM. Hemoglobin A1c predicts diabetes but not cardiovascular disease in nondiabetic women. Am J Med. 2007 Aug; 120(8):720-7. PMID: 17679132; PMCID: PMC2585540.
  34. Jassal DS, Neilan TG, Pradhan AD, Lynch KE, Vlahakes G, Agnihotri AK, Picard MH. Surgical management of infective endocarditis: early predictors of short-term morbidity and mortality. Ann Thorac Surg. 2006 Aug; 82(2):524-9. PMID: 16863755.
    View in: PubMed
  35. Wang L, Liu S, Pradhan AD, Manson JE, Buring JE, Gaziano JM, Sesso HD. Plasma lycopene, other carotenoids, and the risk of type 2 diabetes in women. Am J Epidemiol. 2006 Sep 15; 164(6):576-85. PMID: 16801375.
    View in: PubMed
  36. Neilan TG, Jassal DS, Perez-Sanz TM, Raher MJ, Pradhan AD, Buys ES, Ichinose F, Bayne DB, Halpern EF, Weyman AE, Derumeaux G, Bloch KD, Picard MH, Scherrer-Crosbie M. Tissue Doppler imaging predicts left ventricular dysfunction and mortality in a murine model of cardiac injury. Eur Heart J. 2006 Aug; 27(15):1868-75. PMID: 16717080.
    View in: PubMed
  37. Healy AM, Pickard MD, Pradhan AD, Wang Y, Chen Z, Croce K, Sakuma M, Shi C, Zago AC, Garasic J, Damokosh AI, Dowie TL, Poisson L, Lillie J, Libby P, Ridker PM, Simon DI. Platelet expression profiling and clinical validation of myeloid-related protein-14 as a novel determinant of cardiovascular events. Circulation. 2006 May 16; 113(19):2278-84. PMID: 16682612.
    View in: PubMed
  38. Ndumele CE, Pradhan AD, Ridker PM. Interrelationships between inflammation, C-reactive protein, and insulin resistance. J Cardiometab Syndr. 2006; 1(3):190-6. PMID: 17679826.
    View in: PubMed
  39. Pradhan AD, Manson JE, Hendrix SL, Johnson KC, Wagenknecht LE, Haan MN, Weidner G, Lacroix AZ, Cook NR. Cross-sectional correlates of fasting hyperinsulinaemia in post-menopausal women of different ethnic origin. Diabet Med. 2006 Jan; 23(1):77-85. PMID: 16409570.
    View in: PubMed
  40. Lin J, Ridker PM, Pradhan A, Lee IM, Manson JE, Cook NR, Buring JE, Zhang SM. Hemoglobin A1c concentrations and risk of colorectal cancer in women. Cancer Epidemiol Biomarkers Prev. 2005 Dec; 14(12):3010-2. PMID: 16365028; PMCID: PMC1351341.
  41. Langer RD, Pradhan AD, Lewis CE, Manson JE, Rossouw JE, Hendrix SL, LaCroix AZ, Ridker PM. Baseline associations between postmenopausal hormone therapy and inflammatory, haemostatic, and lipid biomarkers of coronary heart disease. The Women's Health Initiative Observational Study. Thromb Haemost. 2005 Jun; 93(6):1108-16. PMID: 15968396.
    View in: PubMed
  42. Pradhan AD, LaCroix AZ, Langer RD, Trevisan M, Lewis CE, Hsia JA, Oberman A, Kotchen JM, Ridker PM. Tissue plasminogen activator antigen and D-dimer as markers for atherothrombotic risk among healthy postmenopausal women. Circulation. 2004 Jul 20; 110(3):292-300. PMID: 15238458.
    View in: PubMed
  43. Blake GJ, Pradhan AD, Manson JE, Williams GR, Buring J, Ridker PM, Glynn RJ. Hemoglobin A1c level and future cardiovascular events among women. Arch Intern Med. 2004 Apr 12; 164(7):757-61. PMID: 15078645.
    View in: PubMed
  44. Rexrode KM, Pradhan A, Manson JE, Buring JE, Ridker PM. Relationship of total and abdominal adiposity with CRP and IL-6 in women. Ann Epidemiol. 2003 Nov; 13(10):674-82. PMID: 14599731.
    View in: PubMed
  45. Pradhan AD, Manson JE, Meigs JB, Rifai N, Buring JE, Liu S, Ridker PM. Insulin, proinsulin, proinsulin:insulin ratio, and the risk of developing type 2 diabetes mellitus in women. Am J Med. 2003 Apr 15; 114(6):438-44. PMID: 12727576.
    View in: PubMed
  46. Pradhan AD, Cook NR, Buring JE, Manson JE, Ridker PM. C-reactive protein is independently associated with fasting insulin in nondiabetic women. Arterioscler Thromb Vasc Biol. 2003 Apr 01; 23(4):650-5. PMID: 12692007.
    View in: PubMed
  47. Pradhan AD, Skerrett PJ, Manson JE. Obesity, diabetes, and coronary risk in women. J Cardiovasc Risk. 2002 Dec; 9(6):323-30. PMID: 12478201.
    View in: PubMed
  48. Pradhan AD, Manson JE, Rossouw JE, Siscovick DS, Mouton CP, Rifai N, Wallace RB, Jackson RD, Pettinger MB, Ridker PM. Inflammatory biomarkers, hormone replacement therapy, and incident coronary heart disease: prospective analysis from the Women's Health Initiative observational study. JAMA. 2002 Aug 28; 288(8):980-7. PMID: 12190368.
    View in: PubMed
  49. Pradhan AD, Rifai N, Ridker PM. Soluble intercellular adhesion molecule-1, soluble vascular adhesion molecule-1, and the development of symptomatic peripheral arterial disease in men. Circulation. 2002 Aug 13; 106(7):820-5. PMID: 12176954.
    View in: PubMed
  50. Pradhan AD, Ridker PM. Do atherosclerosis and type 2 diabetes share a common inflammatory basis? Eur Heart J. 2002 Jun; 23(11):831-4. PMID: 12042000.
    View in: PubMed
  51. Ridker PM, Shih J, Cook TJ, Clearfield M, Downs JR, Pradhan AD, Weis SE, Gotto AM. Plasma homocysteine concentration, statin therapy, and the risk of first acute coronary events. Circulation. 2002 Apr 16; 105(15):1776-9. PMID: 11956118.
    View in: PubMed
  52. Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM. C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA. 2001 Jul 18; 286(3):327-34. PMID: 11466099.
    View in: PubMed
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